Search clinical trials for: COMT polymorphism

Total 1424 results

University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Recruiting

Correlation Between COMT Val158Met Polymorphism and Dopaminergic Transporter Density (DAT) in Obese Women

Obesity

Brazil
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Pharmacogenetics of Cannabinoid Response

COMT Gene Polymorphism

United States
Assistance Publique - Hôpitaux de Paris

Completed

Compensation Mechanisms in Parkinson's Disease (DATACOMT)

Parkinson Disease

France
University of California, San Diego

Completed

Pharmacologically-augmented Cognitive Therapies (PACTs) for Schizophrenia.

Schizophrenia

United States
Kunming Medical University
National Natural Science Foundation of China

Completed

5-HTR2A, DRD2,and COMT Genes Polymorphisms and Olanzapine Plasma Concentration in Treatment of Early-onset Schizophrenia

Early-onset Schizophrenia

China
Sheffield Hallam University

Unknown

Mod of Cognitive Flexibility by tDCS, Tyrosine Polymorphisms in the COMT Gene

Modulation of Cognitive Flexibility by Transcranial Direct Current Stimulation, Tyrosine Administration and Polymorphisms in the COMT Gene

United Kingdom
Assistance Publique - Hôpitaux de Paris

Completed

Variation of COMT Val158Met Polymorphism Between COM-ON Patients and METHADOSE Patients (COM-ON)

Opioid-related Disorders | Opiate Dependence | Opiate Addiction | Opiate Abuse

France
Manhattan Psychiatric Center
National Institute of Mental Health (NIMH); Albert Einstein College of Medicine

Unknown

Relation of Catechol-O-methyltransferase (COMT) Genotype and Response to Cognitive Remediation Schizophrenia (COMT)

Chronic Schizophrenia

United States
National Institute on Drug Dependence, China
Bronx VA Medical Center

Completed

Association of Functional COMT Val108/Met Polymorphism With Smoking Cessation in Nicotine Replacement Therapy

Nicotine Dependence
Parc de Salut Mar
National Institute on Drug Abuse (NIDA)

Completed

-Methylenedioxymethamphetamine (MDMA, Ecstasy) Induced Changes in Drug Metabolism: Gender and Genetic Polymorphisms

Metabolism | Interaction

Spain
University of Sao Paulo

Unknown

Genetic Association Study Between Single Nucleotide Polymorphisms (SNPs) and Cognitive Performance in Young Bipolar Type I Patients: LICAVALGENE (Licavalgene)

Bipolar

Brazil
Assistance Publique - Hôpitaux de Paris

Completed

COMT Polymorphism and Entacapone Efficacy (COMT)

Parkinson's Disease

France
East Tallinn Central Hospital

Unknown

MOR and COMT SNP Polymorphism and Pain

Pain Relief

Estonia
Austin Health

Completed

Catecholamine-O-Methyl-Transferase(COMT)-Polymorphism in Cardiac Surgery

Cardiac Surgery

Australia
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Predictive Determinants of Nephrotic Syndrome Remission in Patients With At-risk Polymorphism of APOL1 (NEPHROL1)

Focal Segmental Glomerulosclerosis | Nephrotic Syndrome | APOL1 Associated Kidney Disease

France
University of Medicine and Pharmacy "Victor Babes...
Iuliu Hatieganu University of Medicine and Pharmacy; Grigore T. Popa University... and other collaborators

Recruiting

Oral Health and Dental Caries Prevention Intervention for Children in Romania (Smilebright)

Quality of Life | Dental Caries | Early Childhood Caries

Romania
University of Franche-Comté

Not yet recruiting

Physical Activity and Cardiovascular Risk (PACaR)

Chronic Kidney Diseases | Rheumatoid Arthritis | Exercise | Endothelial Dysfunction | Arterial Stiffness
Yi Han
Qianfoshan Hospital

Recruiting

Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency

Renal Insufficiency | Gene Polymorphism | Edoxaban

China
Centre Hospitalier Universitaire de Besancon
Groupement Interrégional de Recherche Clinique et d'Innovation

Not yet recruiting

Regorafenib in Combination With Multimodal Metronomic Chemotherapy for Chemo-resistant Metastatic Colorectal Cancers (CARE)

Metastatic Colorectal Cancer

France
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Evaluation of an E-tool Designed to Facilitate Communication Between Allophone Patients and Pediatricians in Emergency Departments. (ENTENTE)

Language Barrier

France
Ospedale San Raffaele

Recruiting

Genetics in the Progression of Nephropathies

Hypertension | AKI | CKD | Hematologic Malignancy | Ckd-Mbd | ADPKD | Bone Marrow Transplant Complications | CKD (Chronic Kidney Disease) Stage 5D

Italy
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Identification of Biomarkers Associated With the Presence of Malignant Pancreatic Lesions Compared to Benign Lesions. (PANORAMA)

Benign Pancreatic Lesion

France
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
Institute of Liver and Biliary Sciences, India

Recruiting

Prevalence of CYP3A5 Polymorphisms in the Donors and ABCB1 Polymorphisms in the Recipients Undergoing Pediatric Liver Transplant and Their Influence on Tacrolimus Levels and Graft Function.

Pediatric Liver Transplant

India
Helwan University

Not yet recruiting

Palbociclib in Metastatic Breast Cancer: Gene Polymorphism-based Study in Egyptian Patients. (Palbociclib)

Metastatic Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Hormone-receptor-positive Breast Cancer
Mahidol University

Not yet recruiting

The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD.

BMI | Metabolic Syndrome | Insulin Resistance | NAFLD | Genetic Polymorphism | Cardiovascular Disease (CVD) | MASLD | Daily Step Count
Augusto Vaglio

Recruiting

GWAS and EWAS in Patients With Erdheim-Chester Disease

Erdheim-Chester Disease

France, Italy, Spain
Lebanese University
Haykel Hospital

Recruiting

Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA (PTST_PALBEVA)

Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Chemotherapy | Solid Tumor | Immunotherapy | Targeted Therapy | Precision Therapy

Lebanon
Karolinska Institutet

Recruiting

COronary Microcirculation and Troponin Elevation in Septic Shock (COMTESS)

Sepsis | Myocardial Injury | Endothelial Dysfunction | Coronary Microvascular Dysfunction

Sweden
University of Évora
Universidade Nova de Lisboa; Comprehensive Health Research Centre; Unidade Local... and other collaborators

Recruiting

Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome (VitDTracking)

Vitamin D Deficiency | Pregnancy

Portugal
University of Virginia
American Heart Association

Recruiting

Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke (ORCA-AIS)

Ischemic Stroke | CYP2C19 Polymorphism

United States
Zunyi Medical College

Recruiting

CYP2C19 Genotype-Guided P2Y12 Receptor Inhibitor Selection After Complex Percutaneous Coronary Intervention

ACS - Acute Coronary Syndrome | CYP2C19 Polymorphism

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls

Type 2 Diabetes Mellitus | Genetic Mutations | Gene Polymorphisms | Susceptibility, Genetic

China
S.LAB (SOLOWAYS)
Center of New Medical Technologies

Not yet recruiting

Trial to Evaluate the Efficacy of a Zinc, Selenium, and L-Tyrosine Supplement in the Prevention of Thyrotoxicosis in Subjects With r25191G/A SEPP1 Polymorphism (ZEST-PREP)

Thyrotoxicosis

Russian Federation
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DM

Type 2 Diabetes Mellitus | Susceptibility, Genetic

China
Centre Hospitalier Universitaire de Besancon
University of Franche-Comté

Recruiting

Impact of Perceptive, Executive and Emotional Factors on Decision-making of Pedestrian Face to Autonomous Vehicles. (VASIS)

Decision-making

France
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Hyperlactacidemia in Major Abdominal Surgery and Monocarboxylate Receptors (NETTUNO)

Postoperative Complications | Surgical Procedure, Unspecified | Hyperlactatemia | Abdomen Disease

Italy
Novosibirsk Scientific Research Institute for Circulatory...

Recruiting

The Effect of Polymorphism of the GUCY1A3 rs7692387 Gene on Cardiovascular Events After Coronary Artery Bypass Grafting.

to Evaluate the Association of GUCY1A3 rs7692387 Gene Polymorphism Carrier on the Development of Cardiovascular Events After Coronary Artery Bypass Grafting

Russian Federation
Centre Oscar Lambret
Canceropôle Nord Ouest

Recruiting

Superiority Trial Evaluating Digitalized Information Media for Patients With Advanced Sarcomas Receiving Second Line Treatment. (ePPS-2202)

Sarcoma Metastatic | Locally Advanced Soft Tissue Sarcoma

France
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
October 6 University
University of Florida; Beni-Suef University; National Heart Institute, Egypt

Recruiting

Effect of Genetic Polymorphisms on the Clinical Response to SGLT2 Inhibitors in Heart Failure Patients

Heart Failure | Genetic Polymorphisms

United States
Instituto Bernabeu

Not yet recruiting

TRAP Study: Testosterone for Androgen Receptor Polymorphism (TRAP)

Fertility Disorders

Spain
Hopital Nord Franche-Comte

Recruiting

Therapeutic Education Consultations With Diabetic Patients Treated With Intensified Insulin Therapy (DIABETE COACH)

Diabete Mellitus | Insulin Dependent Diabetes

France
Marmara University

Not yet recruiting

Single Gene Polymorphisms Associated With Molar-Incisor Hypomineralization

Molar-Incisor Hypomineralization
Assiut University

Not yet recruiting

Association Between ABO Polymorphism and Gastric/Colorectal Cancers

Gastric Cancer | Colo-rectal Cancer
The Republican Research and Practical Center for...
Belarusian State Medical University

Recruiting

To Develop an Algorithm for Predicting the Unfavorable Course of Sepsis in Children Based on a Comprehensive Assessment of Immunological, Biochemical and Molecular Genetic Markers

Sepsis

Belarus
LI YAN

Not yet recruiting

Study on the Association of GSTP1 and Other Gene Polymorphisms With Platinum-induced Myelosuppression

Non-small Cell Lung Cancer
Janssen Research & Development, LLC

Recruiting

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib (COCOON)

Carcinoma, Non-Small-Cell Lung

United States, Taiwan, Korea, Republic of, Malaysia, Turkey, France, Spain, China, Germany, Argentina
Affiliated Hospital of Nantong University

Not yet recruiting

CYP1A2, ABCB1, CYP2C9 and Plasma Concentration of Agomelatine in Adult Patients With Depression

Depression | Polymerase Chain Reaction | Polymorphism, Genetic | CYP1A2 Polymorphism | Plasma Concentration | CYP2C9 Polymorphism
Technical University of Madrid

Recruiting

Erythrocyte Transport of Lactate During Exercise (TELE Project) (TELE)

Energy Metabolism

Spain

Search clinical trials for: COMT polymorphism

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