Search clinical trials for: Digestive system

Total 250411 results

Zhongda Hospital

Recruiting

Efficacy and Safety of 90Y Microsphere Combined With FOLFIRI and Bevacizumab in Second-line Treatment of CRLM

Colorectal Cancer Metastatic

China
London North West Healthcare NHS Trust

Not yet recruiting

PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome (PSYLIVED)

Lynch Syndrome | Polyposis Syndrome, Hereditary Mixed, 1 | Polyposis Syndrome, Hereditary Mixed, 2

United Kingdom
Fudan University

Not yet recruiting

Perioperative Surufatinib Plus Sintilimab Combined With Chemotherapy in Gastric/Gastroesophageal Junction Adenocarcinoma

Gastric Cancer | Gastro Esophageal Junction Cancer

China
Pfizer

Recruiting

A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination (LTbR)

Melanoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Urothelial Cancer | Advanced or Metastatic Solid Tumors

United States, Puerto Rico
Nanfang Hospital, Southern Medical University

Recruiting

Research on the Mechanisms of Treatment Non-response in Inflammatory Bowel Disease Based on Multi-omics Technology

Inflammatory Bowel Diseases

China
Gulab Devi Hospital

Recruiting

Comparison Between Low Pressure Pneumoperitoneum With High Pressure Pneumoperitoneum in Post-operative Pain, Shoulder Tip Pain and Common Bile Duct Injuries in Patients Undergoing Laparoscopic Cholecystectomy

Pneumoperitoneum | Pain, Postoperative | Cholecystectomy

Pakistan
Pfizer

Not yet recruiting

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Carcinoma, Pancreatic Ductal
Shanghai Zhongshan Hospital

Recruiting

Effects of Growth Hormone Therapy on Metabolic Function in Fatty Liver Post-Pituitary Adenoma Surgery

Growth Hormone Treatment

China
Merck Sharp & Dohme LLC

Not yet recruiting

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

Esophageal Cancer | Esophageal Neoplasms | Gastroesophageal Adenocarcinoma | Gastroesophageal Junction
Shanghai East Hospital

Recruiting

Chemokine and Co-stimulatory Molecule-modified Mesenchymal Stem Cells for the Treatment of Advanced Colorectal Cancer

Advanced Colorectal Cancer

China
Sichuan University

Not yet recruiting

Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
University Hospital, Rouen

Not yet recruiting

De-scalation or swItch of Treatment According to Circulating tuMOr DNA Variation After 2 Cycles of Doublet Chemotherapy Plus Targeted Agent in Metastatic Unresectable Colorectal Cancer (DIAMOND)

Metastatic Colon Cancer
KTO Karatay University

Recruiting

Yoga-Based Breathing Exercise, Colorectal Cancer Surgery

Symptoms and Signs

Turkey
Imperial College London
University of Central Lancashire; University of Nottingham; Cancer Research UK; University of Birmingham and other collaborators

Recruiting

Cancer Loyalty Card Study 2 (CLOCS-2) ((CLOCS-2))

Stomach Cancer | Pancreatic Cancer | Ovarian Cancer | Vulvar Cancer | Bladder Cancer | Endometrial Cancer | Colon Cancer | Liver Cancer | Oesophageal Cancer | Uterine Cancer

United Kingdom
Hopital Montfort

Not yet recruiting

Acceptability and Feasibility of a New Approach to Engage Patients With Steatotic Liver Disease in Physical Activity

Liver Steatosis | MASLD | MASH
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Semiflex Assisted Vacuum Therapy for Perianal Abscesses/Sinuses and Fistula: a Pilot Study (Semiflex Pilot)

Perianal Abscess | Perianal Fistula | Perianal Fistula Due to Crohn's Disease

Netherlands
Ziekenhuis Oost-Limburg

Recruiting

Prevalence of NAFLD in T1DM Patients (PAD1ZOL)

Type 1 Diabetes | NAFLD | Fatty Liver, Nonalcoholic

Belgium
University of Nottingham
Nottingham University Hospitals NHS Trust; Ipsen; National Institute for Health... and other collaborators

Recruiting

Drug-induced Liver Injury: Itching Study

Pruritus | Drug Induced Liver Injury

United Kingdom
University of Tartu

Recruiting

The Feasibility of a Radiological Score Based on CT Signs for Recognizing Salvageable Bowel in Acute Mesenteric Ischemia (AMESIradiol)

Acute Mesenteric Ischemia

Estonia
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of New Post Kasai ILBS Protocol in Biliary Atresia.

Biliary Atresia

India
Ipsen

Not yet recruiting

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment (ELFINITY)

Primary Biliary Cholangitis
Assiut University

Recruiting

Lap Adhesiolysis in Intestinal Obstruction

Adhesions Bowel

Egypt
Revolution Medicines, Inc.

Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Colorectal Cancer | Pancreatic Ductal Adenocarcinoma | Gastrointestinal Cancer | CRC | Metastatic Pancreatic Ductal Adenocarcinoma | PDAC

United States
Sun Yat-sen University

Not yet recruiting

FOLFOX Chemotherapy Plus Fruquintinib and Sintilimab After First-line Treatment in Unresectable Hepatocellular Carcinoma (FOLFOX)

Hepatocellular Carcinoma | Immunotherapy | Second-line Treatment | Anti-angiogenic Therapy | FOLFOX Systemic Chemotherapy
University Rovira i Virgili

Not yet recruiting

Design and Development of a Functional Plant-based Beverage Formulated According to the Main Nutritional Guides for Early Elderly Requirements to Improve Nutritional Status and Immunity for the Early Elderly People to Get Well-healthy Ageing (IMMUGOLD)

Deglutition Disorders
IRCCS San Raffaele

Not yet recruiting

Prospective Registry of EoSinophilic esOphagitis (PRESO)

Eosinophilic Esophagitis
Nanfang Hospital, Southern Medical University

Not yet recruiting

Long-term Outcomes of Duodenal Adenocarcinoma From a Large Cohort

Gastrointestinal Disease
Milton S. Hershey Medical Center
Guardant Health, Inc.; HealthLinc, Inc; PCC Community Wellness Center

Not yet recruiting

Understanding Patient Preference on Colorectal Cancer Screening Options-PSU (U-Screen)

Colo-rectal Cancer

United States
Takeda

Not yet recruiting

A Study to Learn About the Safety of Vedolizumab and How Well it Works in Children and Teenagers With Active Chronic Pouchitis

Pouchitis

Belgium, Spain, Czechia, Italy, Israel, Croatia, Greece, Poland
Peking University Cancer Hospital & Institute

Not yet recruiting

Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer (PKUCH-R09)

Rectal Cancer

China
Peking University

Recruiting

Real-world Study to Evaluate the Efficacy and Safety of Liposome Irinotecan

Colorectal Cancer | Solid Tumor

China
Weill Medical College of Cornell University
Intuitive Surgical

Not yet recruiting

Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair

Hiatal Hernia

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy (BEZURSO 2)

BPC | Non Optimal Response to UDCA

France
University Hospital of Ferrara

Recruiting

Multimodal Prehabilitation in Colorectal Cancer Patients

Colon Cancer | Prehabilitation

Italy
Fudan University

Recruiting

Exploration of Therapeutic Strategies for NeoRAS Wild-type Metastatic Colorectal Cancer Based on Circulating Tumor DNA

Colorectal Cancer Metastatic

China
Shanghai Municipal Hospital of Traditional Chinese...

Not yet recruiting

A Clinical Trial of Chazhu Xiaozhi Decoction Against Non-alcoholic Fatty Liver Disease

Hepatic Steatosis | Symptoms and Signs

China
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

Hepatic Impairment (HI)
Xijing Hospital

Recruiting

Preoperative Adjuvant SOX Plus PL-1 Antibody and FLOT Plus PD-1 Antibody for Locally Advanced dMMR Gastric Cancer

Gastric Cancer | Chemotherapeutic Toxicity | Immune-related Adverse Event

China
Fudan University

Not yet recruiting

Efficacy and Safety of HAIC in Combination With TQB2868 and Ramucirumab for Second-line Treatment of Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma，Bispecific Antibodies, HAIC, Ramucirumab

China
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Not yet recruiting

mPATH-Cloud for Colorectal Cancer Screening (mPATH-Cloud)

Colorectal Cancer

United States
Sun Yat-sen University

Recruiting

Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer

Colorectal Cancer

China
Institut d'Investigació Biomèdica de Girona Dr....

Recruiting

Selection of Surgical Technique in Rectal Cancer (TECARE)

Rectal Neoplasms

Spain
The First Affiliated Hospital of Zhengzhou University

Not yet recruiting

Adjuvant Treatment With Serplulimab，Trastuzumab and SOX in the HER-2 Positive GC/GEJC

HER2-positive Gastric Cancer
CHU de Reims

Not yet recruiting

Prevalence and Factors Associated With Sleep Disorders in Inflammatory Bowel Disease (SOMMICI)

Sleep Disorder | Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis

France
Angiex, Inc.

Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Cancer | Pancreatic Adenocarcinoma | Triple Negative Breast Cancer | Metastatic Solid Tumor | Advanced Cancer | Pancreas Cancer | Locally Advanced Carcinoma

United States
Nanjing First Hospital, Nanjing Medical University

Recruiting

99mTc Labeled FAP Targeted Molecular Probe in Early Diagnosis of Tumors

Pancreatic Cancer | Lung Cancer | Head and Neck Tumor

China
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Recruiting

Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE) (VALUE)

Oesophageal Cancer

United Kingdom
Singlera Genomics Inc.
Fudan University; Beijing Friendship Hospital; Shanxi Provincial Cancer Hospital and other collaborators

Not yet recruiting

INSPIRE: A Multi-Cancer Early Detection Study (INSPIRE)

Cervical Cancer | Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Cholangiocarcinoma | Bladder Cancer | Endometrial Cancer | Liver Cancer
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Recurrence and Bleeding in Colorectal Cancer Patients With Cancer-associated Venous Thrombembolism

Bleeding | Colo-rectal Cancer | Major Bleed | Thrombosis, Venous

China
Ankara Yildirim Beyazıt University

Not yet recruiting

The 4-7-8 Breathing Technique on Pain and Nausea-Vomiting (Pain)

Pain | Nausea | Vomiting | Post Operative Pain | Nausea, Postoperative | Vomiting, Postoperative

Turkey

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