Search clinical trials for: Dose Reduction

Total 25105 results

Cambridge University Hospitals NHS Foundation Trust

Recruiting

Low-Dose IL-2 For The Reduction Of Vascular Inflammation In ACS -Clinical Outcomes & Follow-up Study (IVORY-FINALE)

Acute Coronary Syndromes

United Kingdom
Brazilian Clinical Research Institute
Alliança Diagnostic

Not yet recruiting

Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke (ARCHIMEDES)

Ischemic Stroke
Jessica Merlin
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment (TREETOP)

Chronic Pain | Opioid Use Disorder

United States
Kathelijn Fischer
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Pharmacokinetic-guided Dosing of Emicizumab (DosEmi)

Adolescent | Child | Hemophilia A With Inhibitor | Adult | Hemophilia A Without Inhibitor | Hemophilia A, Severe

Netherlands
Leiden University Medical Center
Dutch Colorectal Cancer Group; Stichting Darmkanker

Not yet recruiting

DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients With Metastatic Colorectal Cancer (DOSAGE)

Colorectal Cancer | Metastatic Cancer | Older Patients | Candidates for Palliative Chemotherapy

Netherlands
Wenzhou Central Hospital

Not yet recruiting

A Randomized Controlled Trial of Auricular Acupressure in Treating Estazolam-dependent Insomnia (ESAAEDI)

Estazolam-dependent Insomnia
University of Liege

Not yet recruiting

Impact of Protamine Dose Reduction on Platelet Aggregation After Extracorporeal Circulation for Minimally Invasive Aortic Valve Replacement Surgery

Protamine Adverse Reaction | Protamine Dose
National Cancer Institute (NCI)

Not yet recruiting

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

Breast Carcinoma | Breast Ductal Carcinoma In Situ | Breast Lobular Carcinoma In Situ | Breast Atypical Hyperplasia

United States
National Cancer Institute (NCI)

Not yet recruiting

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

Breast Carcinoma | Breast Ductal Carcinoma In Situ | Breast Lobular Carcinoma In Situ | Estrogen Receptor-Positive Breast Carcinoma

United States
Johns Hopkins University
Doris Duke Charitable Foundation

Recruiting

Dupilumab De-escalation in Pediatric Atopic Dermatitis

Atopic Dermatitis

United States
YourChoice Therapeutics, Inc.

Recruiting

First in Human Study Evaluating Single Ascending Oral Doses of YCT-529 in Healthy Males

Male Contraception

United Kingdom
VA Office of Research and Development

Recruiting

Dynamic Treatment Regiments for Glucocorticoid Tapering (SMART-RA)

Rheumatoid Arthritis

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Erasmus Medical Center; Prothya Biosolutions

Recruiting

DUPIlumab Dose REDUCtion in Patients With Controlled Atopic Eczema (DUPI REDUCE)

Atopic Dermatitis | Atopic Dermatitis Eczema

Netherlands
Universitaire Ziekenhuizen KU Leuven
Fonds voor Wetenschappelijk Reumaonderzoek (FWRO)

Not yet recruiting

Tapering of Rituximab Based on Interval Prolongation Compared to Disease Activity-guided Dose Reduction in Patients With Rheumatoid Arthritis (RITUXERA)

Rheumatoid Arthritis

Belgium
Silvia Gomez Ordonez

Recruiting

Evaluation of Pain Level Reduction After Low-dose Radiation in Symptomatic Facet Joint Arthritis (LORAFA)

Osteoarthritis, Spine | Lower Back Pain Chronic | Facet Joint Arthrosis

Switzerland
Beijing Tiantan Hospital

Recruiting

Multi-center Study of Artificial Intelligence Model for Gadolinium-based Contrast Agent Reduction in Brain MRI (MAGNET) (MAGNET)

Brain Diseases

China
Centre de recherche du Centre hospitalier universitaire...

Recruiting

Impact in Older Adults of Reducing Anticholinergic and Sedative Rx Burden on Physical Function Measured by Wearables

Physical Function | Deprescribing Anticholinergic and Sedative Medications

Canada
Megan Bradley
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Randomized Trial of Culture Directed Versus Empiric Antibiotics for Urinary Tract Infections in Older Women (REDUCTION)

UTI

United States
Emory University
National Cancer Institute (NCI)

Recruiting

Biomarker-Driven Radiation Therapy Dose Reduction After Transoral Robotic Surgery for the Treatment of HPV-Positive Oropharyngeal Cancer

Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Oropharyngeal HPV-Positive Squamous Cell Carcinoma

United States
xuna

Recruiting

A Study on the Withdrawal of Second-generation Tyrosine Kinase Inhibitors After Dose Reduction in Patients With CML

MMR on 12 Month

China
Iuliu Hatieganu University of Medicine and Pharmacy

Recruiting

Lidocaine Infusion for Propofol Dose Reduction in ERCP Procedure

Sedation

Romania
dafna yahav

Not yet recruiting

Booster Dose of COVID-19 Vaccine for Kidney Transplant Recipients Without Adequate Humoral Response (WHO)

Immunosuppression | COVID-19 Acute Respiratory Distress Syndrome
Massachusetts General Hospital
Cambridge Health Alliance; MaineHealth

Recruiting

Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain

Pain | Marijuana Use | Opioid Use

United States
Kinepict Health Ltd.
Semmelweis University; Bács-Kiskun County Teaching Hospital

Recruiting

Digital Variance Angiography for Contrast Media Dose Reduction in Carotid Artery Stenting

Carotid Artery Diseases

Hungary
Lutris Pharma Ltd.

Recruiting

LUT014 for the Reduction of Dose-Limiting Acneiform Lesions Associated With EGFRI Treatment of mCRC

EGFRI Induced Acneiform Lesions

United States, Israel
Perrigo CSCI
Analyze & Realize

Recruiting

Effects of Arterin Cholesterol for Reduction of Lipid Levels

Blood Cholesterol Lowers | LDL-C

Germany
Memorial Sloan Kettering Cancer Center
National Institutes of Health (NIH)

Recruiting

Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs

Soft Tissue Sarcoma

United States
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Recruiting

Adalimumab Drug Optimisation in Rheumatoid Arthritis Using Therapeutic Drug Monitoring (ADDORA)

Rheumatoid Arthritis

Netherlands
Daniela Francescato Veiga

Recruiting

Single Dose Versus 24 Hours Antibiotic Prophylaxis in Reduction Mammaplasty

Wound Infection | Anti-bacterial Agents | Mammaplasty | Prophylaxis | Plastic Surgery

Brazil
Assistance Publique - Hôpitaux de Paris

Recruiting

BETAmethasone Dose Reduction: Non-Inferiority on the Neurocognitive Outcomes of Children Born Before 32 Weeks of Gestation (BETANINO)

Premature Childbirth

France
Eyenovia Inc.

Recruiting

Microdosed Atropine 0.1% and 0.01% Ophthalmic Solutions for Reduction of Pediatric Myopia Progression

Myopia

United States
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Use of Tocilizumab Drug Levels to Optimize Treatment in RA (TODORA)

Rheumatoid Arthritis

Netherlands
Medical University of Vienna
M.D. Anderson Cancer Center; Odense University Hospital; Radboud University Medical... and other collaborators

Recruiting

Image Guided IMRT, Radiochemotherapy and MRI-based IGABT in Locally Advanced Cervical Cancer (EMBRACEII)

Uterine Cervical Neoplasms

Austria
McMaster University
Canadian Institutes of Health Research (CIHR); David Braley and Nancy Gordon... and other collaborators

Recruiting

Team Approach to Polypharmacy Evaluation and Reduction (Pharmacy)

Polypharmacy | Multi-morbidity | Medication Therapy Management

Canada
University of Alabama at Birmingham
National Heart, Lung, and Blood Institute (NHLBI); University of Pittsburgh; Brigham... and other collaborators

Recruiting

Autoantibody Reduction for Acute Exacerbations of Idiopathic Pulmonary Fibrosis (STRIVE-IPF)

Idiopathic Pulmonary Fibrosis, Acute Fatal Form

United States
McMaster University
Canadian Institutes of Health Research (CIHR); David Braley and Nancy Gordon... and other collaborators

Recruiting

Team Approach to Polypharmacy Evaluation and Reduction (TAPER-RCT)

Polypharmacy | Multi-morbidity | Medication Therapy Management

Canada
Cambridge University Hospitals NHS Foundation Trust

Completed

Low-dose Interleukin-2 for the Reduction of Vascular Inflammation in Acute Coronary Syndromes - IVORY (IVORY)

Acute Coronary Syndromes

United Kingdom
Centers for Disease Control and Prevention
Mayo Clinic; Baylor College of Medicine; University of Alabama at Birmingham; Emory... and other collaborators

Completed

Anthrax Vaccine Clinical Trial to Assess Dose Reduction and Route Change (AVRP)

Healthy

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Low Dose Versus Standard Dose Dexamethasone for Reduction of Swelling in Patients With Primary or Metastatic Brain Tumors

Metastatic Malignant Neoplasm in the Brain | Malignant Brain Neoplasm | Recurrent Malignant Brain Neoplasm

United States
VA Office of Research and Development

Active, not recruiting

Reducing Use of Sleep Medications Assisted by a Digital Insomnia Intervention (SEDATIVE)

Insomnia

United States
Janssen Research & Development, LLC

Completed

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Depressive Disorder, Major

United States, France, Italy, Spain, Hungary, Belgium, Brazil, Bulgaria, Poland
Indiana University

Completed

Radiosurgery Dose Reduction for Brain Metastases on Immunotherapy (RADREMI): A Prospective Pilot Study (RADREMI)

Brain Cancer | Brain Tumor | Brain Metastases

United States
Radboud University Medical Center
UMC Utrecht; Amsterdam UMC, location VUmc; Maastro Clinic, The Netherlands; Rad...

Completed

Uniform FDG-PET Guided Gradient Dose Prescription to Reduce Late Radiation Toxicity (UPGRADE-RT)

Head and Neck Neoplasms | Carcinoma, Squamous Cell

Netherlands
University of Alabama at Birmingham
Bracco Corporate

Active, not recruiting

Evaluating the Performance of AI in Evaluating Breast MRI Performed With Dose Reduction

Breast Malignant Tumor | Breast Benign Tumor

United States
M.D. Anderson Cancer Center

Active, not recruiting

Lesion Detection Assessment in the Liver: Standard vs Low Radiation Dose Using Varied Post-Processing Techniques

Liver Metastases | Colorectal Carcinoma | Colon Carcinoma | Diseases of Liver

United States
Spruce Biosciences

Active, not recruiting

A Ph2b to Evaluate Tildacerfont in the Reduction of Glucocorticoid Steroid Doses in Adult CAH

Congenital Adrenal Hyperplasia

United States, Australia, Brazil, Estonia, Germany, Korea, Republic of, Latvia, Lithuania, Poland, Romania, Spain, Sweden, Turkey, Canada, Italy, United Kingdom
Radboud University Medical Center
University Hospital, Ghent; ZonMw: The Netherlands Organisation for Health... and other collaborators

Active, not recruiting

Dose Reduction of IL17 and IL23 Inhibitors in Psoriasis (BeNeBio)

Psoriasis | Psoriasis Vulgaris

Netherlands, Belgium
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Monkeypox Vaccine

Monkeypox

United States
Abramson Cancer Center at Penn Medicine

Active, not recruiting

TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck

Oropharyngeal Cancer | Human Papilloma Virus | Squamous Cell Carcinoma

United States
Pakistan Institute of Medical Sciences

Completed

In Vivo Comparative Study of Calcium Hydroxide and Triple Antibiotic Paste in Intracanal Medicament in Emergency Pain Reduction

Pain

Pakistan

Search clinical trials for: Dose Reduction

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