Search clinical trials for: Locoregional Control

Total 45970 results

University Hospital A Coruña
Complejo Hospitalario Universitario de Vigo; Complejo Hospitalario Universitario... and other collaborators

Recruiting

Locoregional Control With Radiotherapy of Breast Cancer Patients With MACrometastases Treated With MAstectomy (MACMA) (MACMA)

Breast Cancer

Spain
The Netherlands Cancer Institute
Merck Sharp & Dohme LLC

Not yet recruiting

Carboplatin/Paclitaxel + Pembrolizumab for Locoregionally Advanced Penile Cancer (PRIAM)

Urologic Neoplasms | Urogenital Neoplasms | Penile Cancer | Male Urogenital Diseases | Penile Squamous Cell Carcinoma | Locally Advanced Penile Carcinoma
Sun Yat-sen University

Recruiting

Locoregional Therapy Combined With Bevacizumab and PD1/L1 Inhibitor in Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma | Bevacizumab | Anti-PD1/PDL1 Antibody

China
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Biomarker Driven Patient Selection Neoadjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma

Melanoma | Advanced Melanoma | Melanoma Stage IV | Melanoma Stage III

United States
CHU de Reims

Recruiting

Superiority Randomized Controlled Trial of Ultrasound-guided PENG Block Compared to Surgical Infiltration in the Analgesia of Posterior Total Hip Arthroplasty Surgery (PENGORINF)

Hip Arthrosis | Hip Arthropathy

France
Ascendis Pharma Oncology Division A/S

Recruiting

TransCon (TC) TLR7/8 Agonist, TC IL-2 β/γ, Pembrolizumab Prior to Surgery for Advanced Head and Neck Squamous Cell Carcinoma (BelieveIT-201)

Head and Neck Neoplasms

United States, Spain, Georgia, Hungary, Germany, Italy, Taiwan
National Cancer Institute (NCI)

Recruiting

Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer

Gastric Adenocarcinoma | Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Gastroesophageal Junction Adenocarcinoma | Clinical Stage I Gastric Cancer AJCC v8 | Clinical Stage II Gastric Cancer AJCC v8 | Clinical Stage IVA Gastric... and other conditions

United States
Cancer Hospital of Guangxi Medical University

Recruiting

Sintilimab in Combination With Chemoradiotherapy in High-risk Locoregionally-advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Sintilimab

China
Instituto Brasileiro de Controle do Cancer

Recruiting

Efficacy and Safety of Ultra_HYPofractionated RadiotHerapy in Women With BrEast CaNcer Receiving Regional Nodal Radiation vs Nodal Moderate Hypofractionated Radiotherapy (HYPHEN)

Malignant Breast Neoplasm

Brazil
Sun Yat-sen University

Not yet recruiting

Immune Checkpoint Inhibitor Monotherapy or Combined With Molecular Targeted Drugs / Locoregional Therapy in the Treatment of Hepatocellular Carcinoma

Immune Checkpoint Inhibitor Monotherapy or Combined With Molecular Targeting Drugs / Locoregional Therapy for Hepatocellular Carcinoma

China
University of Texas Southwestern Medical Center
Genentech, Inc.

Recruiting

LOcoregional vs Systemic Therapy in Patients With BCLC Stage B HCC (LOST-B)

Hepatocellular Carcinoma

United States
Wake Forest University Health Sciences

Recruiting

Randomized Control Trial, Cryoablation as an Adjunct to Surgical Stabilization of Rib Fractures

Pain, Postoperative | Rib Fracture Multiple

United States
University Hospital, Angers
Fondation Apicil

Not yet recruiting

Chest Wall Block After Sternotomy: Randomized Controlled Trial in Cardiac Surgery: (PABLOS Study) (PABLOS)

Pain, Postoperative | Cardiac Surgery
Guangxi Medical University
Wuzhou Red Cross Hospital; Wuhan Union Hospital, China; Yunnan Cancer Hospital; Hainan People's Hospital and other collaborators

Not yet recruiting

PD-1 Inhibitor Plus GP as Neoadjuvant Therapy for Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Neoadjuvant Therapy | PD-1 Inhibitor
Sun Yat-sen University

Recruiting

Chemoradiotherapy Plus Anti-PD1 in Recurrent NPC: A Multicenter, Open-label, Randomised, Controlled, Phase III Trial

Nasopharyngeal Carcinoma

China
National Cancer Institute (NCI)

Recruiting

Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

Metastatic Renal Cell Carcinoma | Metastatic Melanoma | Advanced Locoregional Melanoma | Clear Cell Histology

United States
American Hospital of Paris

Not yet recruiting

MUSIC-CARE and Locoregional Anesthesia for Orthopedic Surgery

Music | Regional Anesthesia | Forearm; Injury, Superficial, Multiple (With Elbow)

France
Translational Research in Oncology
Bayer

Recruiting

Regorafenib-pembrolizumab vs. TACE/TARE in Intermediate Stage HCC Beyond Up-to-7 (REPLACE)

Carcinoma, Hepatocellular

Korea, Republic of, United States, Taiwan, Spain, Japan, France, Georgia, Belgium, Germany, Turkey, Italy, Hong Kong, Serbia
UNICANCER
National Cancer Institute, France; GORTEC

Recruiting

Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers (PembroMetaRT)

Squamous Cell Carcinoma of Head and Neck

France
Dr. Paul Buderath

Recruiting

European Collaborative Multicenter Observational Study: Modular Treatment With PMMR and Targeted Compartmental Pelvic Lymphadenectomy Followed by Therapeutic Pelvic and Paraaortic Lymphadenectomy in Node Positive Disease for Locoregional Control in Endometrial Cancer FIGO Stages I-III (PMMR)

Endometrial Cancer

Germany
The University of Hong Kong

Recruiting

Concurrent Chemoradiation and Durvalumab for Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

Hong Kong
Lund University Hospital

Recruiting

Photon Therapy Versus Proton Therapy in Early Tonsil Cancer. (ARTSCAN V)

Tonsil Cancer

Sweden
Dr M. B. Breebaart

Recruiting

Lumbar Erector Spinae Plane Block for Back Surgery (LUMBES)

Pain, Postoperative | Back Pain | Anaesthesia | Anesthesia, Local | Surgery | Spinal Fusion | Nerve Block

Belgium
Astellas Pharma Global Development, Inc.

Recruiting

A Study to Assess the Antitumor Activity, Safety, Pharmacokinetics and Biomarkers of Zolbetuximab (IMAB362) in Participants With Claudin (CLDN) 18.2 Positive, Metastatic or Advanced Unresectable Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma and Locoregional Gastric or GEJ Adenocarcinoma (ILUSTRO)

Gastric Cancer | Pharmacokinetics of Zolbetuximab | Gastro-esophageal Junction (GEJ) Cancer | Pharmacokinetics of Oxaliplatin | Pharmacokinetics of Fluorouracil Bolus (5-FU)

United States, Japan, Italy, Korea, Republic of, Taiwan, France
Technical University of Munich

Recruiting

Impact of Selective Radiation Dose Escalation and Tumour Hypoxia Status on Locoregional Tumour Control After Radiochemotherapy of HNT (Escalox)

Locally Advanced Head and Neck Cancer

Germany
Hoffmann-La Roche

Completed

A Study of Atezolizumab in Combination With Bevacizumab in Spanish Patients With Unresectable or Unsuitable for Locoregional Treatments Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy

Carcinoma, Hepatocellular

Spain
Sun Yat-sen University

Active, not recruiting

PD-1 Antibody Versus Best Supportive Care After Chemoradiation in Locoregionally Advanced Nasopharyngeal Carcinoma (DIPPER)

Nasopharyngeal Neoplasms

China
Gulam Manji
Merck Sharp & Dohme LLC

Completed

Perioperative Chemo and Pembrolizumab in Gastric Cancer

Gastric Cancer | Adenocarcinoma of the Gastroesophageal Junction

United States
Dan Zandberg
Merck Sharp & Dohme LLC

Active, not recruiting

Reirradiation With Pembrolizumab in Locoregional Inoperable Recurrence or Second Primary Squamous Cell CA of the Head and Neck

Recurrent Head and Neck Cancer | Carcinoma, Squamous Cell of Head and Neck

United States
Replimune Inc.
Bristol-Myers Squibb

Withdrawn

Study of RP3 in Combination With Nivolumab and Other Therapy in Patients With Locoregionally Advanced or Recurrent SCCHN

Squamous Cell Carcinoma of Head and Neck | Recurrent Head and Neck Squamous Cell Carcinoma | Locally Advanced Head and Neck Squamous Cell Carcinoma

United States, Spain, United Kingdom, Czechia, France, Germany, Greece, Poland
Dana-Farber Cancer Institute
Bristol-Myers Squibb

Completed

Induction TPN Followed by Nivolumab With Radiation in Locoregionally Advanced Laryngeal and Hypopharyngeal Cancer

Head and Neck Cancer

United States
M.D. Anderson Cancer Center

Withdrawn

Re-irradiation With NBTXR3 in Combination With Pembrolizumab for the Treatment of Inoperable Locoregional Recurrent Head and Neck Squamous Cell Cancer

Recurrent Head and Neck Squamous Cell Carcinoma | Unresectable Head and Neck Squamous Cell Carcinoma
University of Chicago

Active, not recruiting

Chemotherapy and Locoregional Therapy Trial (Surgery or Radiation) for Patients With Head and Neck Cancer (OPTIMA-II)

HNSCC | HPV-Related Squamous Cell Carcinoma

United States
Assistance Publique - Hôpitaux de Paris

Completed

Loco-regional Complications of Pharyngitis in Children: a National Case-Control Study (CAPE)

Pharyngitis

France
Mayo Clinic

Terminated

Study of Proton SBRT and Immunotherapy for Recurrent/Progressive Locoregional or Metastatic Head and Neck Cancer

Head and Neck Cancer

United States
M.D. Anderson Cancer Center
National Institute of Dental and Craniofacial Research (NIDCR)

Active, not recruiting

Neuropathic Pain in Head and Neck Cancer

Head and Neck Cancer

United States
Hospices Civils de Lyon

Completed

Comparison of Two Techniques of Locoregional Analgesia in Total Knee Prosthesis Surgery : Block to the Adductor Channel Versus Peri-articular Local Infiltrations (SALIA)

Analgesic

France
National Cancer Institute, Egypt

Unknown

RCT Comparing 2 Radiotherapy HypoFractionation Schedules In Breast Cancer Patients (Breastcancer)

Radiotherapy Side Effect | Locoregional Recurrence

Egypt
University of Trieste
Cliniche Humanitas Gavazzeni; A.O.U. Città della Salute e della Scienza - Molinette...

Unknown

SAP Versus ESP Block in Multimodal Pain Management in Mini-invasive Thoracic Surgery: an Observational Prospective Multicentric Study

Pain, Postoperative | SAP Block Versus ESP Block | Evaluation of Locoregional Techniques | Multimodal Pain Management

Italy
National Cancer Institute (NCI)

Withdrawn

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

Cervical Carcinoma | Recurrent Melanoma | Vaginal Carcinoma | Esophageal Carcinoma | Mucosal Melanoma | Mucosal Melanoma of the Head and Neck | Oral Cavity Mucosal Melanoma | Stage II Vulvar Cancer AJCC v7 | Stage III Vulvar Cancer AJCC v7 | Stage IIIA Vulvar Cancer AJCC v7 | Stage IIIB Vulvar Cancer AJCC v7 and other conditions

United States
Sun Yat-sen University

Unknown

Mild-dose IMRT for Early-staged Extranodal Nasal-type NK/T-cell Lymphoma With CR Tumor After GELOX Chemotherapy

Lymphoma, | Non-Hodgkin Lymphoma, | Extranodal NK/T-cell Lymphoma,Nasal-type,

China
Sun Yat-sen University
Guangdong Provincial People's Hospital; Affiliated Cancer Hospital of Shantou... and other collaborators

Unknown

A Multicenter Trial Comparing Multi-course Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
University Hospital, Clermont-Ferrand

Completed

Ropivacaine Though Laterosternal Catheters After Cardiac Surgery

Cardiac Surgery

France
Jagiellonian University

Completed

Prophylactic Central Neck Dissection for Papillary Thyroid Cancer

Papillary Thyroid Cancer

Poland
Institute of Oncology Ljubljana

Unknown

Treatment Selection According to Skin Reaction to Cetuximab

Head and Neck Cancer

Slovenia
University Hospital, Tours
Fondation Ildys

Not yet recruiting

Impact of a Coordinated Dietetic-adapted Physical Activity Program on the Percentage of Lean Body Mass in Adults With Cystic Fibrosis Treated With Elexacaftor-Tezacaftor-Ivacaftor: Multicentre Randomised Controlled Trial (DIAPASOM)

Cystic Fibrosis

France
University of Chicago

Not yet recruiting

IntraCERvical Balloon Catheter in the Setting of Induction of Labor for Fetal Loss or Abortion (CERBI)

Fetal Death | Induction of Labor Affected Fetus / Newborn | Abortion, Complete
Cancer Institute and Hospital, Chinese Academy...

Recruiting

SRS/SRT/Hypo-RT Versus HA-WBRT for No More Than 10 Brain Metastases in SCLC (SHARP)

Small-cell Lung Cancer | Brain Metastases | SRS | Stereotactic Radiotherapy | Whole Brain Radiotherpay | Hippocampal-avoidance

China
Northwestern University

Not yet recruiting

Adaptive Messaging to Support Depression Self-Management

Depression

United States
Bradley Nindl
U.S. Army Medical Research and Development Command

Not yet recruiting

Adaptions and Resiliency to Multi-Stressor OpeRations (ARMOR)

Hypogonadism | Musculoskeletal Injury

United States

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