Search clinical trials for: Moderate severity

Total 6920 results

Finnish Institute for Health and Welfare
University of Helsinki; Tampere University; University of Eastern Finland; Strategic...

Recruiting

Adolescent Interpersonal Counseling in Primary Care

Major Depressive Disorder | Depressive Symptoms Mild to Moderate in Severity

Finland
Sir Salimullah Medical College Mitford Hospital

Recruiting

Outcome of Moderate Severity in OPC Poisoning Patients When Treated With Pralidoxime (OPC)

Organophosphorus Poisoning

Bangladesh
Assistance Publique - Hôpitaux de Paris
Gustave Roussy, Cancer Campus, Grand Paris

Not yet recruiting

Calprotectin, a Biomarker of COVID-19 Severity (CALPRO) (CALPRO)

Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia | Old Age | Severe/Moderate Coronavirus

France
University of Central Lancashire

Recruiting

The Effects of Claudication Severity on Functional Outcomes

Intermittent Claudication

United Kingdom
Parc Sanitari Pere Virgili
Consorci Sanitari Integral; Vall d'Hebron Institute of Research; Health and Ageing... and other collaborators

Recruiting

IMAGINE Study Protocol (IMAGINE)

Patients (>=60 Years Old) Suffering From Mild-moderate Stroke (Ischemic or Hemorrhagic, Stroke Severity Assessed by NIHSS <16 Points)

Spain, Sweden
Amgen

Completed

A Comparative Study Between ABP 501 and Humira® in Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

United States, Poland, Canada, Germany, Estonia, Latvia
Novartis Pharmaceuticals

Completed

Study of the Efficacy of Early Intervention With Secukinumab 300 mg s.c. Compared to Narrow-band UVB in Patients With New-onset Moderate to Severe Plaque Psoriasis (STEPin)

Plaque Psoriasis

Spain, United Kingdom, Estonia, Germany, Bulgaria, Finland, Hungary, Poland, Argentina, Canada, Denmark, Switzerland, Sweden
Amgen

Completed

A Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Psoriasis

United States, Poland, Canada, Germany, Estonia, Georgia, Hungary, Latvia
Amgen

Completed

A Study to Investigate ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

United States, Canada, Poland, Estonia, Germany, Hungary, Latvia, Lithuania
Nantes University Hospital

Terminated

A Multicenter Randomized Control Trial in Children With Moderate to Severe Atopic Dermatitis to Assess the Benefit of a Nurse-led One-to-one Education Program in Addition to Standard Care Compared to Standard Care Alone on the Long Term Control of Disease Severity at 6 Months (EDUDA)

Dermatitis, Atopic

France
Iran University of Medical Sciences

Withdrawn

The Effect of a New Antioxidant Combination (ASTED) on Moderate to Severe Thyroid Eye Disease

Thyroid Eye Disease

Iran, Islamic Republic of
SolAeroMed Inc.

Suspended

Safety, Tolerability and Efficacy Of S-1226 in Moderate Severity Covid-19 Bronchiolitis/Pneumonia

Covid19 | SARS-CoV-2 Infection

Canada
Yooyoung Pharmaceutical Co., Ltd.

Completed

Clinical Trial of YYD701-2 for Treatment of Nasolabial Folds

Wrinkle Severity Rating Scale(WSRS) Grade 3 (Moderate) or 4 (Severe) of Nasolabial Folds

Korea, Republic of
Clinical Research Center of the Carolinas
Pfizer

Completed

Improvement of Short Term Outcome of Mild to Moderate Atopic Dermatitis Using a Combination of Crisaborole and a Concomitant Topical Corticosteroid Over a 8 Week Period

Atopic Dermatitis

United States
Novartis Pharmaceuticals

Completed

A Dose Finding Study of AEB071 Assessing Psoriasis Area and Severity Index in Patients With Plaque Psoriasis

Moderate and Severe Plaque Psoriasis

United States, Argentina, Germany, Belgium, Italy, United Kingdom, Turkey, Guatemala, Australia
Astellas Pharma Singapore Pte. Ltd.

Completed

A Survey Evaluating Prevalence, Severity and Associated Factors in East Asian Women With Moderate-to-severe Menopause-related Vasomotor Symptoms (MR-VMS)

Menopause

Korea, Republic of, China, Taiwan
Istanbul Gelisim University

Completed

The Effect of Aerobic Exercise on Immune Biomarkers and Symptoms Severity and Progression in Patients With COVID-19: A Pilot Randomized Control Trial

Covid19

Turkey
Kuopio University Hospital
Business Finland; 4Pharma Ltd.; Finnsusp Ltd.

Completed

Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry Eye

Dry Eye Syndrome

Finland
Bayer

Completed

A Study to Assess Menstrual Cramp Pain Associated With Primary Dysmenorrhea

Dysmenorrhea

United States
Oregon Health and Science University
Allergan

Completed

Botox Cosmetic and the Young Patient With Glabellar Furrows

Glabellar Furrows
Novartis Pharmaceuticals

Completed

Study to Evaluate Psoriasis Severity and Its Psychosocial Impact Using the Simplified Psoriasis Index (SPI), as Well as Long-term Safety, Tolerability and Efficacy of Secukinumab Administered Subcutaneously in Patients With Moderate to Severe Psoriasis (IPSI-PSO)

Psoriasis

France
Novartis Pharmaceuticals

Completed

Extension Study of Secukinumab Prefilled Syringes in Subjects With Moderate to Severe Chronic Plaque-type Psoriasis Completing Preceding Psoriasis Phase III Studies With Secukinumab

Moderate to Severe Plaque-type Psoriasis

Germany, United States, Belgium, Colombia, Spain, Estonia, Hungary, Japan, Lithuania, Taiwan, Australia, Korea, Republic of, Canada, Singapore, Italy, Israel, Sweden, Guatemala, United Kingdom, Argentina, France, Poland, Latvia, Iceland, Finla... and more
The Hong Kong Polytechnic University
Manchester Metropolitan University

Completed

Whole Body Vibration for Children and Young Adults With Moderate Severity of Cerebral Palsy

Cerebral Palsy

Hong Kong
UCB Pharma

Completed

Effect on RLS Symptom Severity After Switching to Neupro® in Patients Who Previously Experienced Augmentation (AURORA)

Restless Legs Syndrome

Germany
AbbVie (prior sponsor, Abbott)
Raffeiner GmbH

Completed

Effectiveness of Adalimumab in Moderate to Severe Plaque Psoriasis Patients With Distinct Co-morbidities (EPIC)

Moderate to Severe Plaque Psoriasis
Hoffmann-La Roche

Completed

A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease Therapy (MAyflOwer RoAD)

Alzheimer's Disease

United States, Spain, France, Korea, Republic of, Australia, Poland, Canada, United Kingdom, Czechia, Italy, Germany, Sweden
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mindfulness-based Personalized Health Planning for Reducing Risk of Heart Disease and Diabetes (AWARENESS)

Prediabetes | Depressive Symptoms Mild to Moderate in Severity

United States
Eisai Inc.

Completed

A Phase 1, Open-Label, Single-Dose, Pharmacokinetic and Safety Study of E7080 (24 mg) Administered to Subjects With Mild, Moderate, and Severe Renal Impairment and to Healthy Subjects

Renal Impairment | Disease Severity

United States
Merck Sharp & Dohme LLC

Completed

Observational Study of Disease Severity in Participants Diagnosed With Crohn's Disease and Long Term Impact of Treatment Strategies in Participants With Moderate to Severe Crohn's Disease (Protocol P06484)

Crohn Disease
Bayer

Completed

Comparative Safety and Efficacy Study of New Bifonazol Spray vs Terbinafine Solution vs Placebo (Porsche)

Tinea Pedis

Germany
Belarusian Medical Academy of Post-Graduate Education
Dr. Reddy's Laboratories Limited

Unknown

Research of Efficient Use of Omeprazole in Combination With Domperidone in Gastroesophageal Reflux Disease of Mild to Moderate Severity

GERD

Belarus
Abbott
Assign Data Management and Biostatistics GmbH

Completed

Quality of Life in Adalimumab Treated Psoriasis Patients Failing Other Biologic Disease Modifying Anti-rheumatic Drugs (QUALITY)

Psoriasis Chronic

Austria
IASO Pharma Inc.

Terminated

Safety and Efficacy Study of Oral Zabofloxacin in Community Acquired Pneumonia

Community Acquired Pneumonia

United States
Hospital Universitari Son Dureta
Espen; This research prize was funded by Nestle Nutrition Institute and by...

Completed

Effect of Gutamine Administration in the Innate Immune System Response in ICU Patients.

Moderate to Severe Trauma, as Defined by an | Injury Severity Score (ISS) > 12 Points Were Included in the Study.

Spain
Anuradha Baminiwatta
University of Melbourne; Curtin University

Recruiting

A Pilot Study Comparing the Efficacy of Traditional Buddhist Mindfulness Training Versus Secular Mindfulness-based Cognitive Therapy for Patients Having Residual Depressive Symptoms

Depression Moderate | Depression Mild

Sri Lanka
RemeGen Co., Ltd.

Not yet recruiting

A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-2)

Systemic Lupus Erythematosus
Abivax S.A.

Not yet recruiting

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease (ENHANCE-CD)

Moderately to Severely Active Crohn Disease
Celldex Therapeutics

Not yet recruiting

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU) (EMBARQ-CSU2)

Chronic Spontaneous Urticaria
University Hospital, Bordeaux

Recruiting

Grade Analysis of Veins by MRI and CT in Post-Thrombotic Syndrome (GrAVITSPT)

Lower Limb Venous Thrombosis

France
Assiut University

Not yet recruiting

TyG Index as a Marker to Predict Severity of Coronary Artery Disease

Coronary Artery Disease
Medical University of Lodz
Poznan University of Medical Sciences; Medical Research Agency, Poland; Clinical... and other collaborators

Not yet recruiting

Comparison of Ustekinumab, Infliximab and Combination Therapy in Moderately to Severely Active Ulcerative Colitis (COMBO-UC)

Inflammatory Bowel Diseases | Ulcerative Colitis
AstraZeneca

Not yet recruiting

Phase IIa Study Evaluating AZD7798 in Crohn's Disease (AMALTHEA)

Moderate to Severe Crohn's Disease

United States, Vietnam, Turkey, Malaysia, Taiwan, Spain, Germany, Italy, Chile, Slovakia, Brazil, Japan, Bulgaria, Ukraine, South Africa, Argentina, Australia, Romania, Austria, Mexico, Sweden
Postgraduate Institute of Dental Sciences Rohtak

Recruiting

COMPARATIVE EVALUATION OF DIRECT PULP CAPPING AND COMPLETE PULPOTOMY IN MATURE PERMANENT MANDIBULAR MOLARS WITH CLINICAL SIGNS INDICATIVE OF MODERATE PULPITIS

Moderate Pulpitis

India
Assiut University

Recruiting

The Significance of Remnant Cholesterol and Carotid Intima Media Thickness in Patients With MAFLD (MAFLD)

Detect the Significance of Remnant Cholesterol in Detection Severity of MAFLD

Egypt
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Randomized Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color Patients (ETHNIC)

Acne Vulgaris

France
Celldex Therapeutics

Not yet recruiting

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (EMBARQ-CSU1)

Chronic Spontaneous Urticaria
Qilu Pharmaceutical (Hainan) Co., Ltd.

Recruiting

Phase 3 Study of QLG2198 in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus

Uremic Pruritus

China
AbbVie

Recruiting

An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)

Dry Eye

United States
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

Hepatic Impairment (HI)
Matthew R. Hoffman

Not yet recruiting

Characterizing the Impact of Presbyphonia on Social Interaction

Presbyphonia

3

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