Search clinical trials for: Positive controlled

Total 21791 results

Jazz Pharmaceuticals

Not yet recruiting

A Phase 3, Randomized, Open-label, Controlled Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

Metastatic HER2-positive Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Randomized, Open, Controlled, Multicenter Phase III Clinical Study of Fluzoparib in Combination With Apatinib Versus Investigator-Selected Chemotherapy for HRD-Positive/HER2-negative Advanced Breast Cancer

Breast Cancer

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Impact on Mortality of a Strategy Including Continuous Positive Airway Pressure Plus High Flow Nasal Cannula Oxygen Therapy Versus High Flow Nasal Cannula Oxygen Therapy Alone in Patients With de Novo Acute Hypoxemic Respiratory Failure: a Prospective, Randomized Controlled Trial. (HighCPAP)

De Novo Hypoxemic Acute Respiratory Failure (hARF)
Liverpool School of Tropical Medicine
Fred Hutchinson Cancer Center; University of Oxford; University of Liverpool; Malawi-Liverpool-Wellcome... and other collaborators

Not yet recruiting

A Controlled Human Infection Model (CHIM) With Intradermal BCG in Malawi (MLWBCGCHIM)

Tuberculosis

Malawi
CanSino Biologics Inc.

Recruiting

A Clinical Trial to Evaluate the Immunogenicity and Safety of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) in Adults Aged 18 to 55 Years

Meningococcal Meningitis

Indonesia
CanSino Biologics Inc.

Recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over

Tetanus

China
G. d'Annunzio University

Not yet recruiting

Probiotics in Special Needs Patients at High Risk for Tooth Decay: a Randomized Controlled Trial.

Intellectual Disability | Caries,Dental | Tooth Decay

Italy
Templeton World Charity Foundation

Recruiting

Character-Strengths Based Coaching For Work-Stress Reduction For Health Workers

Burnout, Psychological | Work Related Stress | Mental Health Issue

India
HRYZ Biotech Co.

Recruiting

HRYZ-T101 Injection for HPV18 Positive Solid Tumor

Cervical Cancer | Head and Neck Squamous Cell Carcinoma | Anal Cancer | Carcinoma of Penis | Carcinoma of Vulva | Carcinoma of Vagina

China
Frieder Schaumburg

Not yet recruiting

Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled Trial (SoTiClin)

Staphylococcal Infections | Staphylococcus Aureus Infection | Skin Infection
Liverpool School of Tropical Medicine
University of Oxford

Recruiting

Using BCG Vaccine to Understand Tuberculosis Infection (Pilot BCG CHIM)

Tuberculosis

United Kingdom
HRYZ Biotech Co.

Recruiting

HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid Tumor

Cervical Cancer | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Cancer | Anal Carcinoma | Vagina Tumor | Carcinoma of Penis | Carcinoma of Vulva

China
Beijing Friendship Hospital

Not yet recruiting

L-DEP Regimen Combined With PD-1 Antibody as Induction Therapy for Epstein-Barr Virus-positive LA-HLH

Lymphoma | Hemophagocytic Lymphohistiocytosis | PD-1 Antibody | Epstein-Barr Virus

China
Mahidol University

Recruiting

Efficacy of N-acetylcysteine to Prevent Anti-tuberculosis Drug-induced Liver Injury: A Randomized Controlled Trial

Hepatitis | Tuberculosis | Drug Induced Liver Injury

Thailand
Western Sydney Local Health District
Centre Of Research Excellence in Tuberculosis Control

Recruiting

The BLAST- 1 Trial - Cephalexin+Amoxicillin-clavulanate for Tuberculosis (BLAST)

Tuberculosis, Pulmonary

Australia
Shanghai Pudong Hospital
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

To Evaluate the Cardiac Safety of Pegylated Liposomal Doxorubicin Concurrently Plus Trastuzumab and Pertuzumab in the Adjuvant Setting for Early-stage HER-2-positive Breast Cancer: a Multicenter, Randomized Controlled Clinical Study (easy laugh)

Breast Cancer

China
Columbia University
Centre for the AIDS Programme of Research in South Africa

Not yet recruiting

An Adaptive Randomized Controlled Trial (ADAP-TIV)

HIV Infections | Multi Drug Resistant Tuberculosis

South Africa
Tilburg University

Recruiting

Parents' Differential Susceptibility to Microtrial

Parent-Child Relations | Parenting | Child Behavior

Netherlands
The First People's Hospital of Lianyungang

Not yet recruiting

B7-H3 Targeting CAR-T Cells Therapy for B7-H3 Positive Solid Tumors

Advanced Solid Tumor

China
Chinese University of Hong Kong
Hong Kong Children's Hospital; Hong Kong Young Women's Christian Association

Recruiting

PACT Programme for Parents of Children With SHCN

Gastrointestinal Diseases | Vascular Diseases | Urologic Diseases | Neurodevelopmental Disorders | Autism Spectrum Disorder | Cleft Lip and Palate | Attention Deficit Hyperactivity Disorder | Developmental Delay

Hong Kong
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c in Combination With Fluvestrant ± Goseraline Versus Placebo Combined With Fulvestrant ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c Versus Placebo in Combination With Letrozole or Anastrozole ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Precise Therapy for Refractory HER2 Positive Advanced Breast Cancer

HER2+ Breast Cancer

China
Institut Pasteur de Madagascar
Centre de Recherche du Centre Hospitalier de l'Université de Montréal; The...

Recruiting

Whole Genome Sequencing of Tuberculosis for Disease Control in Madagascar (TB_WGS_cRCT)

Tuberculosis

Madagascar
Centre Hospitalier Universitaire de la Réunion

Not yet recruiting

Evaluation of the Early Use of the Pressure Relaxer in the Respiratory Impairment of Patients With Amyotrophic Lateral Sclerosis: Multicenter Randomized Controlled Study. (RELAX SLA)

Amyotrophic Lateral Sclerosis
Jan Frystyk
Region of Southern Denmark; Region Zealand; Steno Diabetes Center Sjaelland; Steno...

Recruiting

Home-based Intervention With Semaglutide Treatment Of Neuroleptica-Related Prediabetes (HISTORI)

Schizophrenia | Prediabetic State

Denmark
Xijing Hospital

Not yet recruiting

RC48 for Neoadjuvant Chemotherapy of HER2 Positive Breast Cancer

Breast Cancer | HER2-positive Breast Cancer
Drug Induced Liver Disease Study Group
Beijing Union Pharmaceutical Factory

Recruiting

The Multi-Center, Randomized, Double-blind, Positive Controlled Clinical Trial of Bicyclol in the Treatment of Acute DILI

Drug-Induced Acute Liver Injury

China
Shenzhen People's Hospital

Not yet recruiting

Clinical Study of Clevidipine Butyrate Injection in the Treatment of Hypertensive Emergency and Sub-emergency

Hypertensive Emergency

China
National Cancer Institute (NCI)

Recruiting

T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers

Kita-kyushu Lung Cancer Antigen 1, Human

United States
Hugo Galindo

Not yet recruiting

High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial. (HDIVC)

Covid19
Huiqiang Huang

Recruiting

Tislelizumab in Combination With Lenalidomide in Refractory and Relapsed Elderly Patients With Non-GCB DLBCL

High-grade B-cell Lymphoma | Transformed Lymphoma | EBV-Positive DLBCL, Nos | ALK-Positive Anaplastic Large Cell Lymphoma | Non-GCB/ABC Diffuse Large B-Cell Lymphoma | Follicular Lymphoma Grade IIIb

China
Beijing Chest Hospital

Recruiting

Randomized Controlled Multi-center Short Course Treatment for Rifampicin Resistant Tuberculosis

Tuberculosis

China
University Hospital, Clermont-Ferrand

Recruiting

Effects of End-expiratory Positive Pressure Optimization in Intubated Patients With Healthy Lung or Acute Respiratory Distress Syndrome (PEEP-Réa)

ICU Patients | ARDS | Healthy Lung | Positive End-Expiratory Pressure | Alveolar Recruitment Maneuver

France
GlaxoSmithKline

Recruiting

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of GSK2556286 in Healthy Adult Participants

Tuberculosis

United Kingdom, Netherlands
Acepodia Biotech, Inc.

Recruiting

ACE1702 in Subjects With Advanced or Metastatic HER2-expressing Solid Tumors

Solid Tumor | Metastatic Cancer | HER2-positive Gastric Cancer | HER2-positive Metastatic Breast Cancer | Locally Advanced Solid Tumor

United States, Taiwan
University of La Laguna

Recruiting

Retrieval of Hepatitis C Patients Lost to Follow-up

Hepatitis C

Spain
Dana-Farber Cancer Institute
Puma Biotechnology, Inc.; Translational Breast Cancer Research Consortium

Active, not recruiting

HKI-272 for HER2-Positive Breast Cancer and Brain Metastases

Breast Cancer

United States
IrsiCaixa
José Moltó Marhuenda, PhD, MD; Beatriz Mothe Pujadas PhD,MD; Susana Benet Garrabé... and other collaborators

Completed

A Phase I, Randomized, Double-Blind, Placebo-Controlled Safety, Tolerability and Immunogenicity Study of Candidate HIV-1 Vaccines ChAdOx1.HTI and MVA.HTI With Recombinant HIV-1 Envelope Protein ConM SOSIP.v7 gp140 Vaccine, Adjuvanted With MPLA Liposomes in ART-Suppressed HIV-1 Positive Individuals

HIV Infection

Spain
Eskisehir Osmangazi University

Completed

Investigation of the Effects of Pressure Support Ventilation and Positive Airway Pressure Modes During Extubation

Anesthesia

Turkey
Oxford University Clinical Research Unit, Vietnam
Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam; Hospital for Tropical... and other collaborators

Completed

Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial)

HIV | Tuberculosis | Drug-Induced Liver Injury | Tuberculous Meningitis | IRIS

Indonesia, Vietnam
Dana-Farber Cancer Institute
The Comprehensive and Integrative Medicine Institute of South Korea

Active, not recruiting

Acupuncture for Hot Flashes in Hormone Receptor-Positive Breast Cancer, a Randomized Controlled Trial

Breast Cancer

United States
Aminu Kano Teaching Hospital
NIH Office of AIDS Research (OAR); Fogarty International Center of the National...

Completed

An Educational Intervention Program to Improve the Oral Health of HIV-Positive Children in Kano, Nigeria.

Quality of Life | Dental Caries | HIV | Oral Disease | Oral Infection | Oral Manifestations

Nigeria
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Active, not recruiting

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Lymphoblastic Lymphoma | Childhood Acute Myeloid Leukemia in Remission | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | Childhood Acute Lymphoblastic Leukemia in Remission | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI); Mustang Bio, Inc.

Active, not recruiting

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Refractory Acute Myeloid Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm | Minimal Residual Disease | Acute... and other conditions

United States
University of Alabama at Birmingham

Completed

CPAP Or Nasal Cannula Oxygen for Preterm Infants: A Randomized Controlled Trial (COCO)

Hypoxia | Respiratory Distress Syndrome | Bronchopulmonary Dysplasia | Infant, Newborn, Disease

United States
Kite, A Gilead Company

Terminated

A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

Multiple Myeloma | Ovarian Cancer | Fallopian Tube Cancer | Non-Small Cell Lung Cancer | Triple Negative Breast Cancer | Pancreatic Ductal Adenocarcinoma

United States
CanSino Biologics Inc.

Active, not recruiting

A Study to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over

Tetanus

China
Sarepta Therapeutics, Inc.

Completed

A Randomized, Double-blind, Placebo-controlled Study of Delandistrogene Moxeparvovec (SRP-9001) for Duchenne Muscular Dystrophy (DMD)

Muscular Dystrophy, Duchenne

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Juno Therapeutics, Inc.

Completed

Immunotherapy With BCMA CAR-T Cells in Treating Patients With BCMA Positive Relapsed or Refractory Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma

United States

Search clinical trials for: Positive controlled

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