Search clinical trials for: Protective Immunity

Total 11427 results

National Institute of Allergy and Infectious Diseases...

Recruiting

A Longitudinal Study of COVID-19 Sequelae and Immunity

COVID-19

United States
ImmunityBio, Inc.

Terminated

QUILT-3.039: NANT Pancreatic Cancer Vaccine: Combination Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

Pancreatic Cancer

United States
ImmunityBio, Inc.

Terminated

QUILT-3.070:Pancreatic Cancer Vaccine: Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

Pancreatic Cancer

United States
National Institute of Allergy and Infectious Diseases...
Moderna TX, Inc

Active, not recruiting

Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy Adults

Nipah Virus Infection

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System

Childhood Atypical Teratoid/Rhabdoid Tumor

United States, Canada, Australia
Milton S. Hershey Medical Center

Withdrawn

Effect of Protocatechuic Acid on Biochemical Markers of Immunity Status in Healthy Adults

Immunity

United States
University Hospital, Akershus
Oslo University Hospital; Haukeland University Hospital; Trondheim University... and other collaborators

Active, not recruiting

METIMMOX: Colorectal Cancer METastasis - Shaping Anti-tumor IMMunity by OXaliplatin (METIMMOX)

Colorectal Cancer Metastatic

Norway
USANA Health Sciences
Elegant And Olive Health Clinic, Canada

Completed

A Follow-up Trial of Proglucamune® in the Treatment of Protective Qi Deficiency, a TCM Condition

Protective Qi Insufficiency (a Condition Term From TCM)

Canada
ImmunityBio, Inc.

Active, not recruiting

Combination Immunotherapy Plus Standard-of-Care Chemotherapy Versus Standard-of-Care Chemotherapy for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer

Pancreatic Cancer

United States
Walter Reed National Military Medical Center
Naval Medical Research Center

Active, not recruiting

Melatonin and Vaccine Response, Immunity, and Chronobiology Study (MAVRICS)

Sleep | Vaccine Response | Circadian Rhythm Disorders

United States
ImmunityBio, Inc.

Active, not recruiting

QUILT-3.067: NANT Triple Negative Breast Cancer (TNBC) Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With TNBC Who Have Progressed on or After Standard-of-care Therapy.

Triple Negative Breast Cancer

United States
Weill Medical College of Cornell University
The New York Community Trust

Completed

Impact of Beta-blockers on Physical Function in HFpEF

Heart Failure | Heart Disease | Heart Failure, Diastolic | Heart Failure With Preserved Ejection Fraction | Cardiac Failure

United States
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID)

Active, not recruiting

The Effect of Inflammation and Damage to Lymph Node Structures on Durable Protective Immunity Following Yellow Fever Vaccination

Yellow Fever

United States, Uganda
Moscow Department of Health
Moscow State University of Medicine and Dentistry; National Research Center... and other collaborators

Completed

The Evaluation of Cellular and Humoral Immunity to COVID-19 in Moscow Residents

Covid19 | Respiratory Viral Infection

Russian Federation
National Institute of Allergy and Infectious Diseases...

Completed

Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa...

Malaria

Mali
Imperial College London
Medical Research Council; Wellcome Trust; National Institute for Health Research...

Terminated

A Study of Protective Immunity Against RSV and Influenza in Experimental Human Challenge of Volunteers

Influenza, Human | Respiratory Syncytial Virus Infections

United Kingdom
University of Virginia

Completed

Hallmarks of Protective Immunity in Sequential Rhinovirus Infections in Humans

Healthy Volunteers

United States
Chonbuk National University Hospital

Active, not recruiting

the Efficacy and Safety of Curcuma Longa Extract Mixture on Immune Enhancement

Immunity

Korea, Republic of
ImmunityBio, Inc.

Withdrawn

QUILT-3.057: NANT Neoadjuvant Triple- Negative Breast Cancer (TNBC) Vaccine (TNBC)

Triple Negative Breast Cancer (TNBC)

United States
ImmunityBio, Inc.

Active, not recruiting

QUILT 3.071: NANT Colorectal Cancer (CRC) Vaccine

Colorectal Cancer Metastatic | mCRC

United States
National Institute of Allergy and Infectious Diseases...

Completed

Development of Childhood Anti-Influenza Immunity

Influenza | Influenza Immunisation

United States
Immunoflex Therapeutics Inc.
University of British Columbia; Dicentra Inc.

Completed

Immune Diversity Response to Oral Dosing of Nutritional Health Products in Healthy Participants

Immunity Disorders

Canada
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized Phase I Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV vCP205 Delivered by Alternate Mucosal Routes in HIV-1 Uninfected Adult Volunteers

HIV Infections

United States
USANA Health Sciences
Elegant And Olive Health Clinic, Canada

Completed

An Evaluation of Proglucamune in the Treatment of Protective Qi Insufficiency

Protective Qi Insufficiency

Canada
Hospices Civils de Lyon

Completed

Micronutrient Status Involved in Immunity in Elderly Patients With COVID-19 (MicroCovAging)

Covid19

France
ImmunityBio, Inc.

Withdrawn

QUILT-3.046: NANT Melanoma Vaccine: Combination Immunotherapy in Subjects With Melanoma Who Have Progressed On or After Chemotherapy and PD-1/PD-L1 Therapy

Melanoma
ImmunityBio, Inc.

Withdrawn

QUILT-3.047: NANT Head and Neck Squamous Cell Carcinoma (HNSCC) Vaccine: Combination Immunotherapy in Subjects With HNSCC Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy

Head and Neck Squamous Cell Carcinoma
ImmunityBio, Inc.

Withdrawn

QUILT-3.045: NANT Merkel Cell Carcinoma (MCC) Vaccine: Combination Immunotherapy in Subjects With MCC Who Have Progressed on or After PD-L1 Therapy

Merkel Cell Carcinoma
ImmunityBio, Inc.

Withdrawn

QUILT-3.044: NANT Non-small Cell Lung Cancer (NSCLC) Vaccine: Combination Immunotherapy in Subjects With NSCLC Who Have Progressed After Treatment With PD-1/PD-L1 Inhibitors

Non-small Cell Lung Cancer
ImmunityBio, Inc.

Withdrawn

QUILT-3.049: NANT Triple Negative Breast Cancer (TNBC) Vaccine: Combination Immunotherapy in Subjects With TNBC Who Have Progressed on or After Anthracycline-based Chemotherapy

Triple Negative Breast Cancer
ImmunityBio, Inc.

Withdrawn

QUILT-3.050: NANT Colorectal Cancer (CRC) Vaccine: Combination Immunotherapy in Subjects With Recurrent or Metastatic CRC

Colorectal Cancer
ImmunityBio, Inc.

Withdrawn

QUILT-3.088: NANT Pancreatic Cancer Vaccine

Metastatic Pancreatic Cancer

United States
ImmunityBio, Inc.

Withdrawn

QUILT-3.051: NANT Ovarian Cancer Vaccine: Combination Immunotherapy in Subjects With Epithelial Ovarian Cancer Who Have Progressed on or After Standard-of-care (SoC) Therapy

Ovarian Cancer
ImmunityBio, Inc.

Withdrawn

QUILT-3.072: NANT Hepatocellular Carcinoma (HCC) Vaccine

Hepatocellular Carcinoma Non-resectable | Hepatocellular Carcinoma Recurrent

United States
ImmunityBio, Inc.

Withdrawn

QUILT-3.052: NANT Non-Hodgkin Lymphoma (NHL) Vaccine: Combination Immunotherapy in Subjects With Relapsed CD20-positive NHL

Non Hodgkin Lymphoma
ImmunityBio, Inc.

Withdrawn

QUILT-3.048: NANT Urothelial Cancer Vaccine: Combination Immunotherapy in Subjects With Urothelial Cancer Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy

Urothelial Carcinoma
ImmunityBio, Inc.

Unknown

QUILT-3.090: NANT Squamous Cell Carcinoma (SCC) Vaccine: Subjects With SCC Who Have Progressed

Squamous Cell Carcinoma

United States
ImmunityBio, Inc.

Unknown

QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

Pancreatic Cancer

United States
ImmunityBio, Inc.

Unknown

QUILT-3.080: NANT Pancreatic Cancer Vaccine

Pancreatic Cancer

United States
Immodulon Therapeutics Ltd

Terminated

Study of IMM 101 in Combination With Standard of Care in Patients With Metastatic or Unresectable Cancer (MODULATE)

Metastatic Cancer

France, United Kingdom
Astellas Pharma Inc

Completed

A Study in Kidney Transplant Subjects to Investigate the Optimal Suppression of Immunity to Help Prevent Kidney Rejection (OSAKA)

Kidney Transplantation

Belgium, France, Germany, Italy, Spain, Greece, Switzerland, United Kingdom, Ireland, South Africa, Romania, Sweden, Russian Federation, Austria, Hungary, Poland, Portugal, Netherlands, Argentina, Czechia, Norway, Slovakia
Mayo Clinic

Completed

Analysis of the Mechanisms of Protective Humoral Immunity in Response to the Pneumococcal Vaccine

Healthy

United States
DynPort Vaccine Company LLC, A GDIT Company

Withdrawn

Safety, Tolerability and Immunogenicity of the Venezuelan Equine Encephalitis (VEE) Attenuated Live-Virus Vaccine

Venezuelan Equine Encephalitis

United States
University of Oxford

Completed

A Challenge Study to Assess the Protective Efficacy of Two Malaria Vaccine Candidates (VAC045)

Plasmodium Falciparum Malaria

United Kingdom
Brugmann University Hospital

Completed

Effect of Anti-Inflammatory Agents on Biological Responses to Endotoxin Inhalation in Healthy Subjects

Innate Immunity
Emory University

Completed

Protective Immunity Project 02 (PIP-02)

Immunology | Immunosuppression | Kidney Transplant

United States
Emory University

Completed

Protective Immunity Project 01 (PIP-01)

Kidney Transplantation | Immunity | Immunosuppression

United States
National Institute of Allergy and Infectious Diseases...

Completed

Protective Immunity to Human Cholera in Bangladesh

Cholera

Bangladesh
Shiraz University of Medical Sciences

Completed

Immunomodulatory Effects of Silymarin in Patients With Beta-Thalassemia Major

Immune Abnormalities

Iran, Islamic Republic of
Ain Shams University
King Salman International university

Not yet recruiting

The Effect of Piracetam on Diabetic Peripheral Neuropathy Patients (DPN)

Diabetic Peripheral Neuropathy

3

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