Search clinical trials for: Randomized trials

Total 20574 results

VA Office of Research and Development

Not yet recruiting

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

Depression | Chronic Low Back Pain

United States
University of California, San Francisco

Not yet recruiting

Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP (DOT-Doxy-PEP)

Sexually Transmitted Diseases, Bacterial

United States
JHSPH Center for Clinical Trials
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Multi-Center Clean Air Randomized Controlled Trial in COPD (Clean Air)

Chronic Obstructive Pulmonary Disease (COPD)

United States
GlaxoSmithKline

Recruiting

Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma

Asthma

United States, Canada, Argentina, Australia, Japan, Korea, Republic of, Taiwan
Tor Biering-Sørensen

Not yet recruiting

Nationwide Utilization of Danish Government Electronic Letter System for Increasing Guideline-directed Medical Therapy in Chronic Kidney Disease (NUDGE-CKD)

Chronic Kidney Diseases | Behavior and Behavior Mechanisms

Denmark
McMaster University
Canadian Chiropractic Research Foundation; Surgical Methods Centre, McMaster... and other collaborators

Not yet recruiting

The Effect of Chiropractic Care on Opioid Use for Chronic Spinal Pain: A Feasibility Study

Back Pain

Canada
Novartis Pharmaceuticals

Recruiting

A Proof of Concept and Dose-finding Study of XXB750 in Patients With Heart Failure

Heart Failure

Italy, Spain, United States, Japan, China, Germany, Taiwan, Bulgaria, Denmark, France, Portugal, Slovakia
Tor Biering-Sørensen
Boston Scientific Corporation

Not yet recruiting

Danish Pragmatic Randomized Trial to Evaluate the Effect of HeartLogic-Guided Management on Heart Failure Outcomes (DANLOGIC-HF)

Heart Failure

Denmark
Pliant Therapeutics, Inc.

Recruiting

Randomized, Double-blind Study of Efficacy and Safety of Bexotegrast (PLN-74809) for Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

United States, Australia, Taiwan, Korea, Republic of, Portugal, Germany, Israel, Denmark, New Zealand, Netherlands, Canada, Chile, Czechia, France, Greece, Italy, Poland
Tor Biering-Sørensen

Recruiting

The COLchicine HEART Failure PRESERVED Trial (COLHEART-PRESERVED)

Heart Failure With Preserved Ejection Fraction

Denmark
Escient Pharmaceuticals, Inc

Recruiting

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria (CALM-CSU)

Chronic Spontaneous Urticaria

Spain, United States, Germany, Canada, Poland, Netherlands
Viridian Therapeutics, Inc.

Recruiting

A Randomized, Double-masked, Placebo-controlled Safety, Tolerability, and Efficacy Study of VRDN-001, a Humanized Monoclonal Antibody Directed Against the IGF-1 Receptor, in Participants With Chronic Thyroid Eye Disease (TED)

Thyroid Eye Disease

United States, Turkey
Tor Biering-Sørensen

Recruiting

Coronary Computed Tomography AngioGraphy Prior to Catheter Ablation in Patients With Atrial FIBrillation (FIBCAG)

Atrial Fibrillation

Denmark
Mayo Clinic

Recruiting

Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning vs Standard Radiation Treatment Planning

Cancer Head Neck | Cancer Neck | Cancer, Head

United States
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Technische Universität Dresden; Canadian Critical Care Trials Group and other collaborators

Recruiting

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock (UC-CISSII)

Pathologic Processes | Infections | Sepsis | Systemic Inflammatory Response Syndrome | Inflammation | Shock | Septic Shock

Canada
Shionogi

Recruiting

A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke (REvive)

Acute Ischemic Stroke

Japan, Israel, United States, Australia, Hong Kong
Centre Leon Berard
National Cancer Institute, France

Recruiting

PASCA-MM Study. Impact of the PASCA (PArcours de Santé au Cours du CAncer) Program on Complications Associated With Multiple Myeloma and/or Its Treatments in the Context of a First Hematopoietic Stem Cell Autograft, in Adults Aged 18 to 70. (PASCA -MM)

Multiple Myeloma | Complication

France
Tor Biering-Sørensen

Recruiting

Randomized Comparison of Morning Versus Bedtime Administration of Aspirin: A Cardiovascular Circadian Chronotherapy (C3) Trial (ASPIRIN-C3)

Cardiovascular Diseases | Atherosclerosis | Drug Effect

Denmark
Herlev and Gentofte Hospital

Recruiting

The COLchicine and Atrial FIBrillation Trial (COLFIB)

Atrial Fibrillation

Denmark
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

Focal Onset Seizures

United States, Spain, Italy, Croatia, Portugal, Poland, Chile, Argentina, Austria, Czechia
Sustained Therapeutics Inc.

Recruiting

A Randomized, Controlled Study of Repeat Dose Sustained Release Lidocaine for Treatment of Chronic Scrotal Pain

Chronic Pain

Canada
Peter Siesjö
Lund University

Recruiting

Antisecretory Factor Glioblastoma Phase 2 (AFGB2)

Glioblastoma

Sweden
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE2)

Focal Onset Seizures

United States, Spain, Australia, Poland, Canada, Bulgaria, Italy, United Kingdom
Luzerner Kantonsspital
Stryker SA; Kantonsspital Obwalden; Spital Schwyz

Not yet recruiting

Double Plating Versus Single Plating Techniques in Midshaft Clavicle Fractures

Clavicle Fracture
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation on Radiotherapy-Related Neuropathic Pain (RELAX)

Neuropathic Pain | Radiotherapy Side Effect

China
Marina Klein
University Health Network, Toronto; University of British Columbia; McGill University... and other collaborators

Recruiting

Tecovirimat in Non-hospitalized Patients With Monkeypox (PLATINUM-CAN)

Monkeypox

Canada
AriBio Co., Ltd.

Recruiting

Phase 3, Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of AR1001 in Participants With Early Alzheimer's Disease (Polaris-AD)

Alzheimer Disease

Korea, Republic of, United States, United Kingdom
ACADIA Pharmaceuticals Inc.

Recruiting

Pimavanserin for the Treatment of Irritability Associated With Autism Spectrum Disorder

Irritability Associated With Autism Spectrum Disorder

United States, Spain, France, Australia, Poland, Italy, Serbia, Hungary
Tor Biering-Sørensen
Sanofi; Statens Serum Institut

Recruiting

A Pragmatic Randomized Trial to Evaluate the Effectiveness of High-Dose Quadrivalent Influenza Vaccine vs. Standard-Dose Quadrivalent Influenza Vaccine in Older Adults (DANFLU-2)

Influenza

Denmark
General Administration of Military Health, Tunisia
B. Braun Medical International Trading Company Ltd.

Recruiting

Drug Eluting Balloon Angioplasty Versus Everolimus Platinum Chrome Stent (DEBATE)

Coronary Artery Disease (CAD) | De Novo Stenosis | Percutaneous Coronary Intervention (PCI)

Tunisia
Novartis Pharmaceuticals

Recruiting

An Extension Study of Long-term Efficacy, Safety and Tolerability of Remibrutinib in Chronic Spontaneous Urticaria Patients Who Completed Preceding Studies With Remibrutinib

Chronic Spontaneous Urticaria

United States, Korea, Republic of, Spain, France, Germany, Bulgaria, United Kingdom, China, Hungary, Czechia, Turkey, Argentina, Colombia, Italy, Denmark, Japan, Taiwan, Australia, Singapore, Switzerland, Russian Federation, Thailand and more
University of Sharjah

Not yet recruiting

Pharmacists Interventions on Patients Diabetic, and Obese Patients in the UAE: Randomized Controlled Trials.

Hypertension | Obesity | Pharmacist-Patient Relations | Diabete Type 2
University Health Network, Toronto
University Health Network, Toronto

Recruiting

Platform of Randomized Adaptive Clinical Trials in Critical Illness (PRACTICAL)

Respiratory Insufficiency | Extracorporeal Membrane Oxygenation Complication | Mechanical Ventilation Pressure High

Canada
Wex Pharmaceuticals Inc.

Recruiting

A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain

Chemotherapy-induced Peripheral Neuropathy | Chemotherapy-induced Neuropathic Pain

United States
Code Pharma

Recruiting

Phase IIa Randomized Placebo Controlled Clinical Study of Codivir in Hospitalized Patients With Moderate COVID-19

COVID-19

South Africa
Anthony Tang

Recruiting

Randomized Ablation-based AF Rhythm-control Versus Rate-control in Patients With HF and High-burden AF Extend (RAFT-AF Extend)

Heart Failure | Atrial Fibrillation

Canada
Prestige Biopharma Limited

Recruiting

To Compare the Pharmacokinetics and Safety of PBP1502 and Humira in Healthy Subjects

Healthy Volunteers

Spain
Universität des Saarlandes
Interdisciplinary Center Clinical Trials (IZKS), University Medical Center...

Recruiting

A Prospective, Multicenter, Randomized, Blinded, Sham-controlled, Feasibility Study of Renal Denervation in Patients With Chronic Heart Failure (RE-ADAPT-HF)

Chronic Heart Failure | Cardio-Renal Syndrome

Germany
NovoCure GmbH
Merck Sharp & Dohme LLC

Recruiting

EF-36/Keynote B36: A Pilot, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With Pembrolizumab for First Line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer (KEYNOTE B36)

Non-small Cell Lung Cancer

United States
John Sievenpiper

Not yet recruiting

Meta-analyses of Soy Protein and Its Food Sources for Cholesterol Reduction

Dyslipidemias | Cardiovascular Risk Factor | Dysglycemia

Canada
ProQR Therapeutics

Recruiting

An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene. (BRIGHTEN)

Eye Diseases | Neurologic Manifestations | Retinal Degeneration | Retinal Dystrophies | Sensation Disorders | Vision Disorders | Blindness | Leber Congenital Amaurosis | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

Belgium, Brazil, Canada, Germany, Italy, Netherlands, United Kingdom
Memorial University of Newfoundland
Canadian Institutes of Health Research (CIHR); Eastern Health; Government of... and other collaborators

Recruiting

SurgeCon: An Emergency Department Surge Management Platform (SurgeCon)

Emergency Departments | Length of Stay

Canada
Duke University
National Institute of Mental Health (NIMH)

Recruiting

Comprehensive Adaptive Multisite Prevention of University Student Suicide (CAMPUS)

Suicide

United States
Pfizer

Recruiting

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

Pediatric Migraine

United States, Spain, Canada, China, Poland, United Kingdom, Mexico, Japan, Sweden
University College Dublin
University of Oslo; Universitaire Ziekenhuizen KU Leuven; St Vincent's University... and other collaborators

Recruiting

European Blood Pressure Intensive Control After Stroke (EPICS-Pilot)

Ischemic Stroke | Transient Ischemic Attack

Ireland
University Hospital Tuebingen
Federal Ministry of Health, Germany; University of Ulm; Department of Psychiatry... and other collaborators

Recruiting

Treatment of Major Depressive Disorder With Bilateral Theta Burst Stimulation (TBS-D)

Major Depressive Disorder

Germany
Masonic Cancer Center, University of Minnesota

Recruiting

RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial

Lung Cancer | Adenocarcinoma of Lung

United States
LivaNova

Recruiting

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression (RECOVER)

Treatment Resistant Depression

United States
Organogenesis

Recruiting

Randomized Clinical Study Assessing NuShield Versus Standard of Care in Diabetic Foot Ulcers (DFUs)

Diabetic Foot Ulcer

United States
Oregon Health and Science University
National Institutes of Health (NIH); Indiana University

Recruiting

Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation (VCSIP-ECHO)

Asthma | Pulmonary Function | Wheezing | In Utero Nicotine

United States

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