Search clinical trials for: additional doses

Total 5599 results

Boehringer Ingelheim

Recruiting

A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

Neoplasm Metastasis | Non-Small Cell Lung Cancer

United States, Hong Kong, Spain, Korea, Republic of, China, Israel, Germany, Japan, Singapore, Australia, United Kingdom, Austria, Netherlands, France, Portugal, Sweden, Italy, Belgium
Boehringer Ingelheim

Recruiting

A Study Evaluating Different Doses of BI 765049 When Given Alone and When Given With Ezabenlimab to Patients With Advanced Solid Tumors Expressing the Protein B7-H6 on the Cell Surface

Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung, Pancreatic Neoplasms, Carcinoma, Hepatocellular, Head and Neck Neoplasms, Gastrointestinal Neoplasms

United States, Canada
University Hospital Muenster
Deutsche Krebshilfe e.V., Bonn (Germany)

Recruiting

Treatment Protocol of the NHL-BFM and the NOPHO Study Groups for Mature Aggressive B-cell Lymphoma and Leukemia in Children and Adolescents (B-NHL 2013)

Mature B-cell Non-Hodgkin Lymphoma

Austria, Czechia, Denmark, Finland, Germany, Norway, Sweden, Switzerland
Boehringer Ingelheim

Active, not recruiting

A Study in Patients With Different Types of Advanced Cancer (Solid Tumors) to Test Different Doses of BI 907828 in Combination With BI 754091 (Ezabenlimab) and BI 754111 or BI 907828 in Combination With BI 754091 (Ezabenlimab)

Neoplasms

Spain, United States, Belgium, Germany, Netherlands, Australia, France, Japan, United Kingdom, Singapore, Hungary
GlaxoSmithKline

Completed

Study to Evaluate Immunogenicity and Safety of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine at 9 and 10 Years After Vaccine Administration and Assessment of Re-vaccination With 2 Additional Doses at 10 Years After Initial Vaccination, in Healthy Subjects Aged 60 Years of Age(YOA) and Older

Herpes Zoster

Germany, Czechia, Sweden
GlaxoSmithKline

Completed

A Long-term Follow-up Study (ZOE-LTFU) of Two Studies 110390 (ZOSTER-006) and 113077 (ZOSTER-022) to Assess the Efficacy, Safety, and Immunogenicity Persistence of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine and Assessment of 1 or 2 Additional Doses in Two Subgroups of Older Adults

Herpes Zoster

United States, Australia, Spain, Finland, Germany, Japan, Taiwan, Sweden, Korea, Republic of, Brazil, Mexico, Canada, Italy, France, Czechia, Estonia, Hong Kong, United Kingdom
GlaxoSmithKline

Active, not recruiting

A Study to Test GlaxoSmithKline's (GSK) Herpes Zoster (HZ) Subunit Vaccine's Long-term Immune Response in Previously Vaccinated Kidney Transplant Adults and Then to Test if 2 Additional Doses of the Vaccine Are Safe and Able to Generate an Immune Response

Herpes Zoster

Spain, Canada, Belgium, Finland, Korea, Republic of, Panama, Taiwan
ReAlta Life Sciences, Inc.
FGK Clinical Research GmbH

Completed

A Clinical Study to Determine the Safety, Tolerability and Effect of RLS-0071 Doses When Given to Healthy Adults After Inhaling LPS

Healthy

Germany
BioNTech SE

Completed

A Trial Investigating the Safety and Effects of One or Two Additional Doses of Comirnaty or One Dose of BNT162b2s01 in BNT162-01 or BNT162-04 Trial Subjects

COVID-19 | SARS-CoV-2 Infection

Germany
Fresenius Medical Care Deutschland GmbH

Terminated

Observation of the Immune Response After COVID-19 Additional Vaccine Doses in Chronic Patients in Hemodialysis Therapy (COVID-thIRd)

COVID-19 | Chronic Kidney Diseases | Hemodialysis

Spain, Portugal
AMAG Pharmaceuticals, Inc.

Completed

Compare Efficacy/Safety of Repeat Doses of Ferumoxytol With Iron Sucrose in CKD Subjects With IDA and on Hemodialysis

Iron Deficiency Anemia Treatment | Chronic Kidney Disease(CKD)

United States, Canada, United Kingdom
Memorial Sloan Kettering Cancer Center

Completed

Busulfan, Melphalan, and Fludarabine With Peri-transplant Palifermin, Followed by a T-Cell Depleted Hematopoietic Stem Cell Transplant From HLA Matched or Mismatched Related or Unrelated Donors in Patients With Advanced Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia | Advanced Myelodysplastic Syndromes

United States
Sormland County Council, Sweden
Karolinska Institutet; Helsingfors university

Completed

New Study - Humoral Response to Tick-borne Encephalitis Vaccine in Elderly

Tick-borne Encephalitis

Sweden, Finland
Novartis Pharmaceuticals

Completed

To Evaluate the Effects of Multiple Doses of Nilotinib on the Pharmacokinetics and Metabolism of Midazolam in CML Patients With Additional Extension Phase to Evaluate the Safety of Nilotinib

Chronic Myeloid Leukemia

United Kingdom, Germany
Eli Lilly and Company
Locemia Solutions ULC

Terminated

A Study of Single and Repeated Doses of Glucagon Administered to Participants With Diabetes

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

Canada
Eli Lilly and Company
Locemia Solutions ULC

Completed

A Study of Single or Repeated Doses of Glucagon in Participants With Diabetes

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

Canada
Eli Lilly and Company

Completed

A Study of Investigational Dulaglutide Doses in Participants With Type 2 Diabetes on Metformin Monotherapy

Type 2 Diabetes

United States, Czechia, Poland, Mexico, Puerto Rico, Romania
Eli Lilly and Company

Completed

A Safety Study of LY2886721 Single Doses in Healthy Subjects

Alzheimer's Disease

United States
Eli Lilly and Company

Completed

A Comparison of Two Doses of Pemetrexed in Patients Who Have Lung Cancer

Non-Small Cell Lung Cancer

Turkey
Eli Lilly and Company

Completed

Notch Inhibitor in Advanced Cancer

Advanced Cancer

United States
Eli Lilly and Company

Completed

A Safety Study of LY2886721 Multiple Doses in Healthy Subjects

Alzheimer's Disease

United States
Eli Lilly and Company

Completed

A Study of Multiple Doses of LY3305677 in Healthy Participants

Healthy

United Kingdom
Eli Lilly and Company

Completed

A Study of Multiple Doses of LY2922470 in Participants With Diabetes

Diabetes Mellitus, Type 2

United States
Memorial Sloan Kettering Cancer Center
Pfizer; Dana-Farber Cancer Institute; University of Pittsburgh; University of Virginia

Completed

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

Neurofibromatosis | Meningioma | CNS Cancer | Hemangioblastoma | Intracranial Hemangiopericytoma

United States
Sormland County Council, Sweden

Completed

Humoral Response to Tick-borne Encephalitis Vaccine in Elderly

Tick-borne Encephalitis

Finland, Sweden
Groupe Francophone des Myelodysplasies
Celgene Corporation

Unknown

A Study of the Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q (GFM-Chimio-Rev)

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome

France
Pfizer

Completed

A Global Phase 3 Safety Study of 120 mcg rLP2086 Vaccine in Adolescents and Young Adults Aged 10 to 25 Years

Meningitis, Meningococcal

United States, Australia, Spain, Chile, Finland, Denmark, Estonia, Czech Republic, Germany, Lithuania, Poland, Sweden
Capstone Therapeutics

Completed

A Study to Evaluate the Safety and Efficacy of Additional Doses of AZX100 Drug Product Following Excision of Keloid Scars

Scar Prevention | Scar Reduction

United States
Eli Lilly and Company

Completed

A Study of Multiple Increasing Doses of LY2409021 in Participants With Type 2 Diabetes

Diabetes Mellitus, Type 2

Singapore, United Kingdom
Solvay Pharmaceuticals

Completed

Safety and Efficacy of PROMETRIUM® Capsules in Induction of Secretory Conversion

Secondary Amenorrhea

United States
Eli Lilly and Company

Completed

A Safety Study of LY2811376 Single Doses in Healthy Subjects

Alzheimer's Disease

United States
Eli Lilly and Company

Completed

Guiding Dose Increases in Patients Incompletely Responsive to Usual Doses of Atomoxetine

Attention Deficit Hyperactivity Disorder

Canada, United States
Eli Lilly and Company
ICOS Corporation

Completed

To Determine How Different Doses of Tadalafil Work on Getting and Keeping an Erection 26 or 36 Hours After Taking

Impotence

United States
Eli Lilly and Company

Completed

A Comparison of Tolerability and Efficacy of Different Doses of Duloxetine for the Treatment of Major Depressive Disorder

Depressive Disorder

United States
Cairo University

Recruiting

Effects of Different Doses of Intravenous Lidocaine Infusion on Peri-operative Pain and Incidence of Postoperative Chronic Pain Within ERAS Protocols, a Dose Finding Study.

Perioperative Pain Management

Egypt
Boehringer Ingelheim

Not yet recruiting

A Study in Healthy Men to Test How Well Different Doses of BI 3731579 Are Tolerated

Healthy
Third Harmonic Bio, Inc.

Recruiting

A First in Human Trial Evaluating THB335 in Healthy Participants

Healthy

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Preoxygenation for Tracheal Aspirations in Intensive Care (POXTRA)

ICU Patients Under Invasive Mechanical Ventilation

France
N.N. Petrov National Medical Research Center of...

Recruiting

High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell Tumors (GERMAN)

Germ Cell Tumor

Russian Federation
Bronx VA Medical Center

Not yet recruiting

Dose Optimization of MDMA-Assisted Therapy for PTSD (DosOp)

Posttraumatic Stress Disorder
Anqing Municipal Hospital

Recruiting

The Effect of Dexmedetomidine and Esketamine Combined Infusion Quality of Sleep Undergoing Modified Radical Mastectomy

Dexmedetomidine Plus Esketamine Affect Postoperative Sleep Quality

China
Vaxxas Pty Ltd
Biomedical Advanced Research and Development Authority

Not yet recruiting

Influenza A (H7N9) Vaccine Delivered Intradermally by High-density Microarray Patch (HD-MAP) (HD-MAP)

H7N9 Influenza

Australia
Theodor Bilharz Research Institute

Recruiting

The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study

Procedural Sedation | GIT Endoscopy

Egypt
Osel, Inc.
City of Hope Comprehensive Cancer Center; Miyarisan Pharmaceutical Co., Ltd.

Recruiting

Dose Finding Study of CBM588 in Combination With Nivolumab/Ipilimumab in Advanced Stage Renal Cell Carcinoma

Advanced or Metastatic Renal Cell Carcinoma

United States
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
Wuxi People's Hospital

Recruiting

Low-dose Chemotherapy Under Hypoglycaemia for the Treatment of Relapsed Refractory Advanced Solid Tumours

Solid Tumors, Adult

China
Wave Life Sciences Ltd.

Not yet recruiting

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (RestorAATion-2)

Alpha-1 Antitrypsin Deficiency
Traws Pharma, Inc.

Recruiting

Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers

Healthy Volunteers Only

Australia
Semmelweis University

Recruiting

The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate (NEOKOFF22)

Premature Birth | Respiratory Failure | Apnea of Prematurity

Hungary
Eilean Therapeutics

Recruiting

Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers

AML

Australia

3

Subscribe