Search clinical trials for: endpoint driven

Total 687 results

Novartis Pharmaceuticals

Completed

Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure (ATMOSPHERE)

Chronic Heart Failure

China, United States, Belgium, Colombia, India, Korea, Republic of, Poland, Romania, Italy, Spain, Austria, Estonia, France, Germany, Japan, Taiwan, Turkey, Netherlands, Sweden, Switzerland, United Kingdom, Thailand, Australia, Ireland, Russian Federation and more
Novartis Pharmaceuticals

Completed

Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure (ASTRONAUT)

Acute Decompensated Heart Failure | Congestive Heart Failure

Colombia, Czech Republic, India, Italy, Belgium, Turkey, Argentina, France, Germany, Israel, Spain, Canada, Taiwan, United States, Singapore, Russian Federation, Philippines, Slovakia, Sweden, Hungary, Finland, Poland, Romania, Brazil
Lithuanian University of Health Sciences
Sligo General Hospital; KlaipÄ-da University

Recruiting

BMI-Driven Tolerability and Efficacy of Entresto in Heart Failure Patients (BETTER-HF)

Heart Failure | Obesity

Lithuania
National University Hospital, Singapore

Not yet recruiting

A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers (VALUE-CHECK)

Carcinoma, Hepatocellular | Gastric Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Oesophageal Cancer | GastroEsophageal Cancer

Singapore
Istanbul Demiroglu Bilim University

Not yet recruiting

Assessing the Impact of Monitor Maintenance Package Utilization

Patient Safety | Alarm Fatigue

Turkey
Ray Therapeutics, Inc.
The Vision Research and Assessment Institute (VRAI)

Recruiting

Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Retinitis Pigmentosa Patients

Retinitis Pigmentosa

United States
Gitte Fredberg Persson MD PhD

Recruiting

Longitudinal Study of Local Ablative Therapy in Oligometastatic Disease (OLIGO-DK)

Surgery | Oligometastatic Disease | Radiotherapy | Metastases | Stereotactic Radiation | Ablation Techniques

Denmark
Lirio
Cone Health

Not yet recruiting

Precision Nudging for Hypertension Management: Observational Study

Hypertension
Kansas City Heart Rhythm Research Foundation

Recruiting

Dynamic Data-Driven Management of Atrial Fibrillation Using Implantable Cardiac Monitors: The MONITOR-AF Study

Atrial Fibrillation

United States
AbbVie

Recruiting

A Study to Learn How Safe and Effective Risankizumab is When Compared to Deucravacitinib to Treat Participants With Moderate Plaque Psoriasis and Who Need to Try Systemic Treatment (Works Throughout the Whole Body)

Moderate Plaque Psoriasis

United States, Puerto Rico
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome (DRIVENT)

Acute Respiratory Distress Syndrome ARDS
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Effect of Vericiguat on Endpoint Events in Acute Coronary Syndrome( ACS）Patients With Ejection Fraction <45%

Acute Coronary Syndrome | Heart Failure With Reduced Ejection Fraction

China
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Setting a PERSONalized Outcome in ASthma: the PERSONAS Study. A Patient Driven Outcome (PDO) Study (PERSONAS)

Bronchial Asthma

Italy
Istituto Auxologico Italiano
Azienda Ospedaliera Città della Salute e della Scienza di Torino; Ospedale...

Recruiting

Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral Sclerosis (DRIVEALS)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis

Italy
University of Chicago

Recruiting

Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation

Obstructive Sleep Apnea

United States
National University Hospital, Singapore

Recruiting

Comparison of Pacing Lead Design on Left Bundle Branch Pacing Outcomes (LEAD-LBP)

Pacemaker DDD

Singapore
Zhujiang Hospital

Not yet recruiting

Effectiveness of Atorvastatin in Preventing Cerebrovascular Events After Flow Diverter Implantation

Efficacy Endpoint: no New Cerebrovascular Adverse Events Within 1 Year | Safety Endpoint: no New Moderate or Serious Adverse Events Within 1 Year | All-cause Mortality Events (Within 1 Year) | Incident Ischemic Stroke Events (Within 1 Year) | New Hemorrhagic Stroke Events (Within 1 Year) | New... and other conditions
Istituto Nazionale di Ricovero e Cura per Anziani
European Union

Recruiting

engAGE: Managing cognitivE decliNe throuGh Theatre Therapy, Artificial Intelligence and Social Robots drivEn Interventions (engAGE)

Mild Cognitive Impairment | Older Adults

Italy, Norway, Switzerland
Zhejiang Cancer Hospital

Recruiting

Genotype-driven Weekly Irinotecan Liposomes in Combination With Capecitabine-based Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer

Rectal Cancer

China
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Biomarker Driven Patient Selection Neoadjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma

Melanoma | Advanced Melanoma | Melanoma Stage IV | Melanoma Stage III

United States
Deciphera Pharmaceuticals LLC

Recruiting

Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway

Melanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene Mutation

United States
Kessler Foundation

Not yet recruiting

Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and MCI

Aging

United States
Bristol-Myers Squibb

Recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease (TargetTau-1)

Alzheimer Disease, Early Onset

United States, Australia, Belgium, Canada, France, Japan, Korea, Republic of, Netherlands, Singapore, Spain, Sweden, United Kingdom, Denmark, Germany, Italy, Poland
Amneal Pharmaceuticals, LLC
CBCC Global Inc.; Amneal EU, Limited

Not yet recruiting

A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

Ocular Hypertension | Open-angle Glaucoma

United States
Coloplast A/S

Recruiting

TFL Driven Urinary System Treatment Study (TFL-DUST)

Urologic Diseases

France, Spain
Pro-Change Behavior Systems

Recruiting

Compass for Care: A Theory-driven Mobile Solution to Promote Well-being Among Caregivers of Individuals With ADRD (Compass4Care)

Dementia | Mental Health

United States
AstraZeneca

Recruiting

A Study to Assess Multidomain Endpoints of an ECG Patch

Acute Decompensated Heart Failure

United Kingdom
Amsterdam UMC, location VUmc
University of Bergen; University of Oxford; Centre Hospitalier Universitaire... and other collaborators

Recruiting

Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression (VASCULAIDRETRO)

Peripheral Arterial Disease | Aneurysm Abdominal

Netherlands, United Kingdom, Finland, Germany, Portugal, Serbia
Zheng Liu ENT
Zhejiang Xianju Pharma Tech. Co., Ltd

Recruiting

A Multicenter, Randomized, Double-blind, Three-arm, Parallel Clinical Endpoint Bioequivalence Study of Monometasone Furoate Nasal Spray in Patients With Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

China
London North West Healthcare NHS Trust

Recruiting

SECURE Trial: Stress Echocardiography With Carotid Ultrasound vs Routine CT Coronary Angiography in Chronic Coronary Syndrome for Endpoints (SECURE)

Coronary Artery Disease | Coronary Disease | Chronic Coronary Syndrome

United Kingdom
McGill University Health Centre/Research Institute...
Heart and Stroke Foundation of Canada

Recruiting

Canagliflozin in Advanced Renal Disease With MRI Endpoints (CARe-MRI)

ESRD, CKD Stage 4, CKD Stage 5

Canada
Eli Lilly and Company

Recruiting

A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis

Plaque Psoriasis

United States
Boston University
Takeda

Recruiting

Respiratory Microbiota and Immune Response in CVID

CVID

United States
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

Korea, Republic of, United Kingdom, United States, Poland, Germany, Brazil, Spain, Taiwan, Hungary, Japan, Canada, Argentina, Australia
Xueqin Yang

Recruiting

RecistTM Criteria in Evaluating the Efficacy of Targeted Therapy for NSCLC

NSCLC | Targeted Therapy | Evaluation

China
MRC/UVRI and LSHTM Uganda Research Unit
London School of Hygiene and Tropical Medicine; Assistance Publique - Hôpitaux... and other collaborators

Not yet recruiting

Implementing Oral (Event-driven and Daily) and Long-acting Pre-Exposure Prophylaxis in Mobile Men in Sub-Saharan Africa (MOBILEMEN)

HIV
State University of New York at Buffalo
National Institute on Aging (NIA)

Recruiting

The Role of Neutrophils in the Age-driven Decline in Anti-pneumococcal Vaccine Responses

Aging

United States
Incyte Corporation

Recruiting

A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V2)

NonSegmental Vitiligo

Germany, United States, Poland, Italy, Canada, France, Bulgaria, Hungary, United Kingdom
University of Minnesota

Not yet recruiting

Quantifying tACS-driven Improvement of Working Memory in Depression

Depression
DermBiont, Inc.

Recruiting

A Trial to Evaluate the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratosis

Seborrheic Keratosis

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA); Maryland Department of Health and...

Not yet recruiting

Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

HIV Infections | Addiction | Substance Use Disorders | Opioid Use | Drug Use | Intravenous Drug Usage

United States
University Hospital Tuebingen
Cooperative Weichteilsarkom Study Group; Deutsches Konsortium fürTranslationale... and other collaborators

Recruiting

Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision) (PerVision)

Ewing Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma

Germany
Takeda

Recruiting

A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 52 Weeks of Treatment

Plaque Psoriasis

United States, Canada, Poland, Italy, Japan
Chinese University of Hong Kong
Hong Kong Young Women's Christian Association; Hong Kong Christian Service; Hong... and other collaborators

Recruiting

Pai.ACT - An Artificial Intelligence Driven Chatbot Assisted ACT

Intellectual Disability | Neurodevelopmental Disorders | Autism Spectrum Disorder | Attention Deficit Hyperactivity Disorder | Communication Disorders | Specific Learning Disorder | Motor Disorders

Hong Kong
Rigshospitalet, Denmark
University of Copenhagen

Recruiting

Human Mitochondrial Stress-driven Obesity Resistance (MITO-OB-RES)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Disorder

Denmark
Sanofi

Recruiting

A Study to Evaluate Efficacy and Safety of SAR441566 in Adults With Plaque Psoriasis (SPECIFI-PSO)

Psoriasis

Chile, Germany, Mauritius, Japan, Canada, United States, Georgia, Turkey, Spain, Czechia, Hungary, Poland, Portugal, United Kingdom, China, Argentina
Children's National Research Institute

Recruiting

Therapeutic Endpoint in Pediatric IBD Conditions

Inflammatory Bowel Diseases | Crohn Disease | Colitis, Ulcerative

United States
Chinese University of Hong Kong

Recruiting

Pilot Study of Motor-cable-driven System for Stroke Wrist and Forearm Rehabilitation

Stroke

Hong Kong
Chinese University of Hong Kong

Recruiting

Computer Aided Diagnosis (CADx) for Colorectal Polyps Resect-and-Discard Strategy (CADx)

Colonic Polyp

Hong Kong
Centro di Riferimento Oncologico - Aviano

Recruiting

Prostate Oligometastatic Cancer Management Driven by Disease Biology et/or Immunoactivity (PROMETEO) (PROMETEO)

Oligometastatic Prostate Cancer

Italy

Search clinical trials for: endpoint driven

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