Lung Resection and Pulmonary Rehabilitation
Outcomes of Pulmonary Rehabilitation After Lung Resection in Patients With Non-Small Cell Lung Cancer
Lung cancer is the most common cancer in the world and surgical resection remains the gold standard curative treatment in early stage non-small cell lung cancer. However, surgery itself is the direct cause of pulmonary function impairment, which dramatically reduces patients tolerance to exercise and their quality of life. Pulmonary rehabilitation (PR) complements surgical treatment and improves patients' exercise and functional capacity, decreases dyspnea, improves health status.
Our aim is to examine the effectiveness of PR applied after lung resection in patients with lung cancer, 2- To determine whether the respiratory exercise training given to patients who could not participate in the PR program is effective.
調査の概要
詳細な説明
Pulmonary rehabilitation (PR) is an evidence-based, interdisciplinary, comprehensive exercise program that targets patients with symptomatic chronic respiratory disease. PR integrates exercise and training interventions into a personalized treatment program. PR has become an important component of the general treatment strategy in patients with high-risk surgical diseases such as lung resection. It helps patients return to normal not only physically, but also emotionally and mentally. In patients with lung cancer, preoperative PR increases exercise capacity, decreases post-operative morbidity and mortality. Although it is reported that the PR program applied in the post-operative period increases physical performance and improves the quality of life, referral of patients in need of the PR unit is less than 25%. There is a need to increase the awareness of both pulmonologists and thoracic surgeons about the benefits of the PR program, which is a non-pharmacological and effective intervention.
The investigators have had two objectives in this study. 1- To examine the effectiveness of PR applied after lung resection in patients with lung cancer, 2- To determine whether the respiratory exercise training given to patients who could not participate in the PR program is effective.
An 8-week comprehensive outpatient PR program will applied to half of 66 patients with non-small cell lung cancer who underwent lung resection, and the other half received respiratory exercise training. After the intervention, the results of both groups will compare.
研究の種類
入学 (実際)
段階
- 適用できない
連絡先と場所
研究場所
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-
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İzmir、七面鳥、35620
- İlknur Naz Gürşan
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参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
説明
Inclusion Criteria:
- Patients who had undergone surgery for non-small cell lung cancer in the last two years
- Patients who had no chemotherapy or radiotherapy
Exclusion Criteria:
- Patients who were found unsuitable with the cardiology consultation
- Patients with psychiatric problems
- Patients with severe joint diseases
- Reluctant patients
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：処理
- 割り当て：非ランダム化
- 介入モデル：並列代入
- マスキング：なし（オープンラベル）
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
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実験的：Pulmonary Rehabilitation Group
An 8-week comprehensive outpatient PR program including respiratory exercises, aerobic and strengthening training
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Exercise training
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他の：Control Group
Respiratory exercises
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Exercise training
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Exercise Capacity
時間枠：up to 8 weeks
|
Six minutes walk test
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up to 8 weeks
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Respiratory Functions
時間枠：up to 8 weeks
|
Pulmonary Function Test Pulmonary function test (PFT) which is noninvasive tests that show how well the lungs are working. The tests will measure FEV1; It is the volume of air (in liters) exhaled in the first second during forced exhalation after maximal inspiration. FVC: It s the amount of air that can be forcibly exhaled from your lungs after taking the deepest breath possible, as measured by spirometry FEV1/FVC: It represents the proportion of a person's vital capacity that they are able to expire in the first second of forced expiration (FEV1) to the full, forced vital capacity (FVC). |
up to 8 weeks
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|
Dyspnea Sensation
時間枠：up to 8 weeks
|
Modified Medical Research Council (MMRC)" dyspnea scale, which consists of 5 items ranging between 1 and 5, to determine the severity of patients' shortness of breath.
Higher scores mean a worse outcome.
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up to 8 weeks
|
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Disease Specific Quality of Life
時間枠：up to 8 weeks
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St. George's Respiratory Questionnaire (SGRQ) to determine disease-specific quality of life.
At this scale, high scores define worsened disease and increased symptoms.
Higher scores mean a worse outcome.
|
up to 8 weeks
|
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Anxiety
時間枠：up to 8 weeks
|
Hospital Anxiety and Depression (HAD) Inventory for assessment of anxiety and depression.
In this scale; scores of anxiety and depression are calculated separately.
The maximum score for both is 21 and high scores correspond to high degree anxiety and depression.
Cut-off scores for anxiety and depression were determined as 10/11 and 7/8 respectively.
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up to 8 weeks
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Depression
時間枠：up to 8 weeks
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Hospital Anxiety and Depression (HAD) Inventory for assessment of anxiety and depression.
In this scale; scores of anxiety and depression are calculated separately.
The maximum score for both is 21 and high scores correspond to high degree anxiety and depression.
Cut-off scores for anxiety and depression were determined as 10/11 and 7/8 respectively.
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up to 8 weeks
|
|
Body Mass Index
時間枠：up to 8 weeks
|
Body mass index is calculated by dividing body mass by the square of length in meters
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up to 8 weeks
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協力者と研究者
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
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