Study of Pemetrexed and Carboplatin Compared With Etoposide Carboplatin to Treat Extensive-Stage Small Cell Lung Cancer
2009년 10월 20일 업데이트: Eli Lilly and Company
A Randomized Phase 3 Trial of Alimta (Pemetrexed) and Carboplatin Versus Etoposide and Carboplatin in Extensive-Stage Small Cell Lung Cancer
This study is a Phase 3, global, multi-center, open-label study of patients with extensive-stage small cell lung cancer.
Eligible patients will be randomly assigned to receive either pemetrexed plus carboplatin or etoposide plus carboplatin.
It is anticipated that pemetrexed plus carboplatin will offer similar survival benefits as compared to etoposide plus carboplatin.
연구 개요
연구 유형
중재적
등록 (실제)
908
단계
- 3단계
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 장소
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Athens, 그리스, 11527
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Heraklion, 그리스, 71110
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Marousi Attikis, 그리스, 15126
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Pylaia/Thessaloniki, 그리스, 57001
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Cape Town, 남아프리카, 7925
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Durban, 남아프리카, 4091
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Parktown, 남아프리카, 2193
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Amsterdam, 네덜란드, 1081 HV
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Arnhem, 네덜란드, 6815 AD
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Den Bosch, 네덜란드, 5211 NL
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Groningen, 네덜란드, 9713 GZ
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Harderwijk, 네덜란드, 3844 DG
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Heerlen, 네덜란드, 4619 PC
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Auckland, 뉴질랜드, 1030
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Christchurch, 뉴질랜드, 8020
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Wellington, 뉴질랜드, 6002
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Niao Sung Hsiang, 대만, 833
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Taichung, 대만, 407
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Taipei, 대만, 100
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Seoul, 대한민국, 138-736
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Borstel, 독일, 23845
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Freiburg, 독일, 79106
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Gauting, 독일, D-82131
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Großhansdorf, 독일, D-22927
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Hamburg, 독일, D-21075
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Heidelberg, 독일, 69126
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Hemer, 독일, D-58675
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Kassel, 독일, 34125
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Köln, 독일, D-51109
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Nürnberg, 독일, 90419
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Regensburg, 독일, D-93049
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Rostock, 독일, 18057
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Stralsund, 독일, 18435
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Chelyabinsk, 러시아 연방, 454087
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Engels, 러시아 연방, 413115
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Kazan, 러시아 연방, 420029
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Murmansk, 러시아 연방, 183047
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Saint Petersburg, 러시아 연방, 198255
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Stavropol, 러시아 연방, 355047
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Bucharest, 루마니아, 022328
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Cluj-Napoca, 루마니아, 3400
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Alabama
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Huntsville, Alabama, 미국, 35805
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Alaska
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Anchorage, Alaska, 미국, 99508
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Arkansas
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Fayetteville, Arkansas, 미국, 72703
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California
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Burbank, California, 미국, 91505
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La Jolla, California, 미국, 92093
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Los Angeles, California, 미국, 90095
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Mission Hills, California, 미국, 91345
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Orange, California, 미국, 92868
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Poway, California, 미국, 92064
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Florida
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Fort Myers, Florida, 미국, 33916
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Jacksonville, Florida, 미국, 32256
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Miami, Florida, 미국, 33136
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Orlando, Florida, 미국, 32806
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Illinois
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Chicago, Illinois, 미국, 60637
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Springfield, Illinois, 미국, 62701
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Kansas
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Wichita, Kansas, 미국, 67214
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Kentucky
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Lexington, Kentucky, 미국, 40536
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Louisville, Kentucky, 미국, 40402
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Maine
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Scarborough, Maine, 미국, 04074
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Massachusetts
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Boston, Massachusetts, 미국, 02118
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Michigan
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Detroit, Michigan, 미국, 48201
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Minnesota
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Minneapolis, Minnesota, 미국, 55455
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Missouri
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Kansas City, Missouri, 미국, 64111
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St Louis, Missouri, 미국, 63110
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Nebraska
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Lincoln, Nebraska, 미국, 68510
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New Jersey
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Sparta, New Jersey, 미국, 07871
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New Mexico
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Albuquerque, New Mexico, 미국, 87106
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Santa Fe, New Mexico, 미국, 87505
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North Carolina
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Chapel Hill, North Carolina, 미국, 27599
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Concord, North Carolina, 미국, 28025
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Ohio
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Cincinnati, Ohio, 미국, 45267
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Columbus, Ohio, 미국, 43221
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Zanesville, Ohio, 미국, 43701
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Oregon
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Portland, Oregon, 미국, 97213
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Pennsylvania
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Dunmore, Pennsylvania, 미국, 18512
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East Stroudsburg, Pennsylvania, 미국, 18301
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Ephrata, Pennsylvania, 미국, 17522
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Media, Pennsylvania, 미국, 19063
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Philadelphia, Pennsylvania, 미국, 19141
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Wilkes-Barre, Pennsylvania, 미국, 18711
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South Carolina
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Charleston, South Carolina, 미국, 29406
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Columbia, South Carolina, 미국, 29210
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Tennessee
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Chattanooga, Tennessee, 미국, 37404
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Knoxville, Tennessee, 미국, 37920
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Memphis, Tennessee, 미국, 38120
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Nashville, Tennessee, 미국, 37203
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Texas
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Austin, Texas, 미국, 78705
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Dallas, Texas, 미국, 75237
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Fort Worth, Texas, 미국, 76104
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Houston, Texas, 미국, 77060
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San Antonio, Texas, 미국, 78258
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Virginia
-
Richmond, Virginia, 미국, 23298
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Washington
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Everett, Washington, 미국, 98201
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Wisconsin
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Madison, Wisconsin, 미국, 53792
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Brussels, 벨기에, 1090
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Edegem, 벨기에, 2650
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-
Leuven, 벨기에, 3000
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Liege, 벨기에, 4000
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Liège, 벨기에, 4000
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Florianópolis, 브라질, 88034000
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Fortaleza, 브라질, 60430-230
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Jau, 브라질, 17210-120
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Sao Paulo, 브라질, 01277-900
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Alicante, 스페인, 03010
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Badalona, 스페인, 08915
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Barakaldo, 스페인, 48903
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Barcelona, 스페인, 08907
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Madrid, 스페인, 28041
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Zaragoza, 스페인, 50009
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Bahia Blanca, 아르헨티나
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Buenos Aires, 아르헨티나, 1427
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Mar Del Plata, 아르헨티나, 7600
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Rosario, 아르헨티나, 2000
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Tucumain, 아르헨티나, 4000
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Manchester, 영국, M20 4BX
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Avon
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Bristol, Avon, 영국, BS2 8ED
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Cornwall
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Truro, Cornwall, 영국, TR1 3LJ
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Essex
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Chelmsford, Essex, 영국, CM1 7ET
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Scotland
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Aberdeen, Scotland, 영국, AB25 2ZN
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Glasgow, Scotland, 영국, G12 0YN
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West Midlands
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Birmingham, West Midlands, 영국, B15 2TH
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Wolverhampton, West Midlands, 영국, WV10 0QP
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Graz, 오스트리아, 8036
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-
Linz, 오스트리아, A-4010
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Wien, 오스트리아, A-1140
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Bergamo, 이탈리아, 24128
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Livorno, 이탈리아, 57128
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Monteforte Irpino, 이탈리아, 83024
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Orbassano, 이탈리아, 10043
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Parma, 이탈리아, 43100
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Ravenna, 이탈리아, 48020
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Rome, 이탈리아, 00149
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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San Sisto, 이탈리아, 06156
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Ahmedabad, 인도, 380016
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Bangalore, 인도, 560027
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Kolkata, 인도, 700053
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Ludhiana, 인도, 141001
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Mumbai, 인도, 400 012
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New Delhi, 인도, 110029
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Pune, 인도, 411001
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Trivandrum, 인도, 695 011
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Beijing, 중국, 100021
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Guang Zhou, 중국, 510080
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Shanghai, 중국, 200433
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Besevler/Ankara, 칠면조, 06500
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Gaziantep, 칠면조
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Istanbul, 칠면조, 34760
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Izmir, 칠면조, 35100
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Samsun, 칠면조, 55139
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Coimbra, 포르투갈, 3040-853
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Lisbon, 포르투갈, 1649-035
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Porto, 포르투갈, 4200-072
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Santa Maria Da Feira, 포르투갈, 4520-211
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Vila Nova De Gaia, 포르투갈, 4434-502
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Gdansk, 폴란드, 80-211
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Krakow-Nowa Huta, 폴란드, PL-31-826
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Otwock, 폴란드, 05-400
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Szczecin-Zdunowo, 폴란드
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Zabrze-Biskupice, 폴란드, 41-803
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San Juan, 푸에르토 리코, 00921
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Brest, 프랑스, 29609
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Caen, 프랑스, 14033
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Clichy, 프랑스, 92118
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Grenoble, 프랑스, 38043
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Lille, 프랑스, 59020
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Lyon, 프랑스, 69317
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Marseille, 프랑스, 13009
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Montpellier, 프랑스, 34295
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Deszk, 헝가리, 6772
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Pecs, 헝가리, 7623
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Szekesfehervar, 헝가리, 8000
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Szombathely, 헝가리, 9700
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Torokbalint, 헝가리, 2045
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Zalaegerszeg, 헝가리, 8900
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
-
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New South Wales
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Camperdown, New South Wales, 호주, 2050
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Coffs Harbour, New South Wales, 호주, 2450
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Port Macquarie, New South Wales, 호주, 2444
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Wollongong, New South Wales, 호주, 2500
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Queensland
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Brisbane, Queensland, 호주, 4029
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Chermisdie, Queensland, 호주, 4032
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Redcliffe, Queensland, 호주, 4020
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
South Brisbane, Queensland, 호주, 4101
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Townsville, Queensland, 호주, 4810
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
South Australia
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Adelaide, South Australia, 호주, 5000
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Woodville, South Australia, 호주, 5011
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Tasmania
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Hobart, Tasmania, 호주, 7001
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Victoria
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Frankston, Victoria, 호주, 3199
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Geelong, Victoria, 호주, 3220
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Wodonga, Victoria, 호주, 3690
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
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참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
18년 이상 (성인, 고령자)
건강한 자원 봉사자를 받아들입니다
아니
연구 대상 성별
모두
설명
Inclusion Criteria:
- Clinical diagnosis of extensive stage small cell lung cancer (SCLC)
- Capable of self-care but may be unable to carry out any work activities.
- No prior anticancer therapy for SCLC
Exclusion Criteria:
- have previously participated in a study involving pemetrexed
- have received treatment within the last 30 days with a drug that has not received regulatory approval for any indication
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 치료
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
|
활성 비교기: 비
|
Area under the curve (AUC) 5, intravenous (IV), every 21 days x 6 cycles
100 mg/m2, intravenous (IV), days 1-3 x 6 cycles
|
|
실험적: ㅏ
|
500 mg/m2, 정맥 주사(IV), 매 21일 x 6주기
다른 이름들:
Area under the curve (AUC) 5, intravenous (IV), every 21 days x 6 cycles
|
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Overall Survival
기간: baseline to date of death from any cause (up to 19.6 months)
|
Overall survival is the duration from enrollment to death.
For patients who are alive, overall survival is censored at the last contact.
|
baseline to date of death from any cause (up to 19.6 months)
|
2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Overall Survival (Subgroups)
기간: baseline to date of death from any cause (up to 19.6 months)
|
The effects of individual baseline factors (sex, race, Eastern Cooperative Oncology Group (ECOG) performance, region, lactate dehydrogenase (LDH), age, number of metastatic sites, and history of brain metastases) on overall survival are reported.
For two subgroups - LDH<=upper limit of normal and brain metastases=yes, the upper limits of the 95% confidence interval were not calculable for the etoposide+carboplatin group - instead the number of participants in these two subgroups are presented as a post-hoc outcome measure.
|
baseline to date of death from any cause (up to 19.6 months)
|
|
Progression Free Survival
기간: baseline to measured progressive disease (up to 14.7 months)
|
The period from study entry until disease progression, death or date of last contact.
|
baseline to measured progressive disease (up to 14.7 months)
|
|
Change From Baseline to Each Cycle in Functional Assessment of Cancer Therapy - Lung (FACT-L)
기간: baseline and 6 cycles (21-day cycles)
|
FACT-L measures following domains of health-related quality of life (HR-QL): physical well-being, social/family well-being, emotional well-being, functional well-being, and additional concerns of lung cancer.
Total scores range from 0 to 136, with higher scores representing better HR-QL.
A clinically meaningful change is considered to be 5 points.
|
baseline and 6 cycles (21-day cycles)
|
|
Overall Survival (Subgroups: LDH<=Upper Limit of Normal and History of Brain Metastases=Yes)
기간: baseline to date of death due to any cause (up to 19.6 months)
|
The effects of individual baseline factors (lactate dehydrogenase (LDH) and history of brain metastases) on overall survival are reported.
The Upper Limits of the 95% Confidence Intervals were not calculable for these factors in the Etoposide+Carboplatin group.
The number of participants in these subgroup are instead presented as a Post-Hoc Outcome Measure.
|
baseline to date of death due to any cause (up to 19.6 months)
|
공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
수사관
- 연구 책임자: Call 1-877-CTLILLY(1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST), Eli Lilly and Company
간행물 및 유용한 링크
연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작
2006년 8월 1일
기본 완료 (실제)
2008년 6월 1일
연구 완료 (실제)
2008년 6월 1일
연구 등록 날짜
최초 제출
2006년 8월 10일
QC 기준을 충족하는 최초 제출
2006년 8월 10일
처음 게시됨 (추정)
2006년 8월 15일
연구 기록 업데이트
마지막 업데이트 게시됨 (추정)
2009년 10월 28일
QC 기준을 충족하는 마지막 업데이트 제출
2009년 10월 20일
마지막으로 확인됨
2009년 10월 1일
추가 정보
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .