- ICH GCP
- USA klinikai vizsgálatok nyilvántartása
- Klinikai vizsgálat NCT00363415
Study of Pemetrexed and Carboplatin Compared With Etoposide Carboplatin to Treat Extensive-Stage Small Cell Lung Cancer
2009. október 20. frissítette: Eli Lilly and Company
A Randomized Phase 3 Trial of Alimta (Pemetrexed) and Carboplatin Versus Etoposide and Carboplatin in Extensive-Stage Small Cell Lung Cancer
This study is a Phase 3, global, multi-center, open-label study of patients with extensive-stage small cell lung cancer.
Eligible patients will be randomly assigned to receive either pemetrexed plus carboplatin or etoposide plus carboplatin.
It is anticipated that pemetrexed plus carboplatin will offer similar survival benefits as compared to etoposide plus carboplatin.
A tanulmány áttekintése
Állapot
Befejezve
Körülmények
Beavatkozás / kezelés
Tanulmány típusa
Beavatkozó
Beiratkozás (Tényleges)
908
Fázis
- 3. fázis
Kapcsolatok és helyek
Ez a rész a vizsgálatot végzők elérhetőségeit, valamint a vizsgálat lefolytatásának helyére vonatkozó információkat tartalmazza.
Tanulmányi helyek
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Bahia Blanca, Argentína
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Buenos Aires, Argentína, 1427
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Mar Del Plata, Argentína, 7600
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Rosario, Argentína, 2000
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Tucumain, Argentína, 4000
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Graz, Ausztria, 8036
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Linz, Ausztria, A-4010
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Wien, Ausztria, A-1140
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New South Wales
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Camperdown, New South Wales, Ausztrália, 2050
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Coffs Harbour, New South Wales, Ausztrália, 2450
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Port Macquarie, New South Wales, Ausztrália, 2444
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Wollongong, New South Wales, Ausztrália, 2500
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Queensland
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Brisbane, Queensland, Ausztrália, 4029
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Chermisdie, Queensland, Ausztrália, 4032
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Redcliffe, Queensland, Ausztrália, 4020
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South Brisbane, Queensland, Ausztrália, 4101
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Townsville, Queensland, Ausztrália, 4810
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South Australia
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Adelaide, South Australia, Ausztrália, 5000
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Woodville, South Australia, Ausztrália, 5011
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Tasmania
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Hobart, Tasmania, Ausztrália, 7001
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Victoria
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Frankston, Victoria, Ausztrália, 3199
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Geelong, Victoria, Ausztrália, 3220
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Wodonga, Victoria, Ausztrália, 3690
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Brussels, Belgium, 1090
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Edegem, Belgium, 2650
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Leuven, Belgium, 3000
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Liege, Belgium, 4000
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Liège, Belgium, 4000
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Florianópolis, Brazília, 88034000
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Fortaleza, Brazília, 60430-230
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Jau, Brazília, 17210-120
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Sao Paulo, Brazília, 01277-900
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Cape Town, Dél-Afrika, 7925
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Durban, Dél-Afrika, 4091
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Parktown, Dél-Afrika, 2193
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Manchester, Egyesült Királyság, M20 4BX
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Avon
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Bristol, Avon, Egyesült Királyság, BS2 8ED
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Cornwall
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Truro, Cornwall, Egyesült Királyság, TR1 3LJ
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Essex
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Chelmsford, Essex, Egyesült Királyság, CM1 7ET
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Scotland
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Aberdeen, Scotland, Egyesült Királyság, AB25 2ZN
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Glasgow, Scotland, Egyesült Királyság, G12 0YN
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West Midlands
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Birmingham, West Midlands, Egyesült Királyság, B15 2TH
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Wolverhampton, West Midlands, Egyesült Királyság, WV10 0QP
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Alabama
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Huntsville, Alabama, Egyesült Államok, 35805
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Alaska
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Anchorage, Alaska, Egyesült Államok, 99508
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Arkansas
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Fayetteville, Arkansas, Egyesült Államok, 72703
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California
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Burbank, California, Egyesült Államok, 91505
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La Jolla, California, Egyesült Államok, 92093
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Los Angeles, California, Egyesült Államok, 90095
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Mission Hills, California, Egyesült Államok, 91345
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Orange, California, Egyesült Államok, 92868
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Poway, California, Egyesült Államok, 92064
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Florida
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Fort Myers, Florida, Egyesült Államok, 33916
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Jacksonville, Florida, Egyesült Államok, 32256
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Miami, Florida, Egyesült Államok, 33136
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Orlando, Florida, Egyesült Államok, 32806
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Illinois
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Chicago, Illinois, Egyesült Államok, 60637
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Springfield, Illinois, Egyesült Államok, 62701
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Kansas
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Wichita, Kansas, Egyesült Államok, 67214
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Kentucky
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Lexington, Kentucky, Egyesült Államok, 40536
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Louisville, Kentucky, Egyesült Államok, 40402
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Maine
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Scarborough, Maine, Egyesült Államok, 04074
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Massachusetts
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Boston, Massachusetts, Egyesült Államok, 02118
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Michigan
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Detroit, Michigan, Egyesült Államok, 48201
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Minnesota
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Minneapolis, Minnesota, Egyesült Államok, 55455
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Missouri
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Kansas City, Missouri, Egyesült Államok, 64111
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St Louis, Missouri, Egyesült Államok, 63110
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Nebraska
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Lincoln, Nebraska, Egyesült Államok, 68510
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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New Jersey
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Sparta, New Jersey, Egyesült Államok, 07871
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New Mexico
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Albuquerque, New Mexico, Egyesült Államok, 87106
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Santa Fe, New Mexico, Egyesült Államok, 87505
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North Carolina
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Chapel Hill, North Carolina, Egyesült Államok, 27599
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Concord, North Carolina, Egyesült Államok, 28025
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Ohio
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Cincinnati, Ohio, Egyesült Államok, 45267
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Columbus, Ohio, Egyesült Államok, 43221
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Zanesville, Ohio, Egyesült Államok, 43701
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Oregon
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Portland, Oregon, Egyesült Államok, 97213
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Pennsylvania
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Dunmore, Pennsylvania, Egyesült Államok, 18512
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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East Stroudsburg, Pennsylvania, Egyesült Államok, 18301
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Ephrata, Pennsylvania, Egyesült Államok, 17522
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Media, Pennsylvania, Egyesült Államok, 19063
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Philadelphia, Pennsylvania, Egyesült Államok, 19141
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Wilkes-Barre, Pennsylvania, Egyesült Államok, 18711
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South Carolina
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Charleston, South Carolina, Egyesült Államok, 29406
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Columbia, South Carolina, Egyesült Államok, 29210
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Tennessee
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Chattanooga, Tennessee, Egyesült Államok, 37404
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Knoxville, Tennessee, Egyesült Államok, 37920
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Memphis, Tennessee, Egyesült Államok, 38120
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Nashville, Tennessee, Egyesült Államok, 37203
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Texas
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Austin, Texas, Egyesült Államok, 78705
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Dallas, Texas, Egyesült Államok, 75237
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Fort Worth, Texas, Egyesült Államok, 76104
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Houston, Texas, Egyesült Államok, 77060
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San Antonio, Texas, Egyesült Államok, 78258
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Virginia
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Richmond, Virginia, Egyesült Államok, 23298
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Washington
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Everett, Washington, Egyesült Államok, 98201
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Wisconsin
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Madison, Wisconsin, Egyesült Államok, 53792
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Brest, Franciaország, 29609
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Caen, Franciaország, 14033
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Clichy, Franciaország, 92118
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Grenoble, Franciaország, 38043
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Lille, Franciaország, 59020
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Lyon, Franciaország, 69317
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Marseille, Franciaország, 13009
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Montpellier, Franciaország, 34295
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Athens, Görögország, 11527
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Heraklion, Görögország, 71110
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Marousi Attikis, Görögország, 15126
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Pylaia/Thessaloniki, Görögország, 57001
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Amsterdam, Hollandia, 1081 HV
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Arnhem, Hollandia, 6815 AD
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Den Bosch, Hollandia, 5211 NL
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Groningen, Hollandia, 9713 GZ
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Harderwijk, Hollandia, 3844 DG
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Heerlen, Hollandia, 4619 PC
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Ahmedabad, India, 380016
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Bangalore, India, 560027
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Kolkata, India, 700053
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Ludhiana, India, 141001
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Mumbai, India, 400 012
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New Delhi, India, 110029
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Pune, India, 411001
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Trivandrum, India, 695 011
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Seoul, Koreai Köztársaság, 138-736
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Beijing, Kína, 100021
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Guang Zhou, Kína, 510080
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Shanghai, Kína, 200433
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Gdansk, Lengyelország, 80-211
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Krakow-Nowa Huta, Lengyelország, PL-31-826
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Otwock, Lengyelország, 05-400
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Szczecin-Zdunowo, Lengyelország
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Zabrze-Biskupice, Lengyelország, 41-803
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Deszk, Magyarország, 6772
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Pecs, Magyarország, 7623
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Szekesfehervar, Magyarország, 8000
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Szombathely, Magyarország, 9700
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Torokbalint, Magyarország, 2045
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Zalaegerszeg, Magyarország, 8900
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Borstel, Németország, 23845
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Freiburg, Németország, 79106
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Gauting, Németország, D-82131
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Großhansdorf, Németország, D-22927
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Hamburg, Németország, D-21075
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Heidelberg, Németország, 69126
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Hemer, Németország, D-58675
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kassel, Németország, 34125
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Köln, Németország, D-51109
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Nürnberg, Németország, 90419
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Regensburg, Németország, D-93049
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Rostock, Németország, 18057
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Stralsund, Németország, 18435
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Bergamo, Olaszország, 24128
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Livorno, Olaszország, 57128
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Monteforte Irpino, Olaszország, 83024
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Orbassano, Olaszország, 10043
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Parma, Olaszország, 43100
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Ravenna, Olaszország, 48020
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Rome, Olaszország, 00149
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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San Sisto, Olaszország, 06156
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Chelyabinsk, Orosz Föderáció, 454087
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Engels, Orosz Föderáció, 413115
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Kazan, Orosz Föderáció, 420029
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Murmansk, Orosz Föderáció, 183047
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Saint Petersburg, Orosz Föderáció, 198255
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Stavropol, Orosz Föderáció, 355047
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Coimbra, Portugália, 3040-853
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Lisbon, Portugália, 1649-035
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Porto, Portugália, 4200-072
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Santa Maria Da Feira, Portugália, 4520-211
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Vila Nova De Gaia, Portugália, 4434-502
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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San Juan, Puerto Rico, 00921
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Besevler/Ankara, Pulyka, 06500
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Gaziantep, Pulyka
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Istanbul, Pulyka, 34760
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Izmir, Pulyka, 35100
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Samsun, Pulyka, 55139
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Bucharest, Románia, 022328
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Cluj-Napoca, Románia, 3400
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Alicante, Spanyolország, 03010
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Badalona, Spanyolország, 08915
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Barakaldo, Spanyolország, 48903
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Barcelona, Spanyolország, 08907
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Madrid, Spanyolország, 28041
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Zaragoza, Spanyolország, 50009
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Niao Sung Hsiang, Tajvan, 833
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Taichung, Tajvan, 407
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Taipei, Tajvan, 100
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Auckland, Új Zéland, 1030
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Christchurch, Új Zéland, 8020
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Wellington, Új Zéland, 6002
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Részvételi kritériumok
A kutatók olyan embereket keresnek, akik megfelelnek egy bizonyos leírásnak, az úgynevezett jogosultsági kritériumoknak. Néhány példa ezekre a kritériumokra a személy általános egészségi állapota vagy a korábbi kezelések.
Jogosultsági kritériumok
Tanulmányozható életkorok
18 év és régebbi (Felnőtt, Idősebb felnőtt)
Egészséges önkénteseket fogad
Nem
Tanulmányozható nemek
Összes
Leírás
Inclusion Criteria:
- Clinical diagnosis of extensive stage small cell lung cancer (SCLC)
- Capable of self-care but may be unable to carry out any work activities.
- No prior anticancer therapy for SCLC
Exclusion Criteria:
- have previously participated in a study involving pemetrexed
- have received treatment within the last 30 days with a drug that has not received regulatory approval for any indication
Tanulási terv
Ez a rész a vizsgálati terv részleteit tartalmazza, beleértve a vizsgálat megtervezését és a vizsgálat mérését.
Hogyan készül a tanulmány?
Tervezési részletek
- Elsődleges cél: Kezelés
- Kiosztás: Véletlenszerűsített
- Beavatkozó modell: Párhuzamos hozzárendelés
- Maszkolás: Nincs (Open Label)
Fegyverek és beavatkozások
Résztvevő csoport / kar |
Beavatkozás / kezelés |
---|---|
Aktív összehasonlító: B
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Area under the curve (AUC) 5, intravenous (IV), every 21 days x 6 cycles
100 mg/m2, intravenous (IV), days 1-3 x 6 cycles
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Kísérleti: A
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500 mg/m2, intravénás (IV), 21 naponként x 6 ciklus
Más nevek:
Area under the curve (AUC) 5, intravenous (IV), every 21 days x 6 cycles
|
Mit mér a tanulmány?
Elsődleges eredményintézkedések
Eredménymérő |
Intézkedés leírása |
Időkeret |
---|---|---|
Overall Survival
Időkeret: baseline to date of death from any cause (up to 19.6 months)
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Overall survival is the duration from enrollment to death.
For patients who are alive, overall survival is censored at the last contact.
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baseline to date of death from any cause (up to 19.6 months)
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Másodlagos eredményintézkedések
Eredménymérő |
Intézkedés leírása |
Időkeret |
---|---|---|
Overall Survival (Subgroups)
Időkeret: baseline to date of death from any cause (up to 19.6 months)
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The effects of individual baseline factors (sex, race, Eastern Cooperative Oncology Group (ECOG) performance, region, lactate dehydrogenase (LDH), age, number of metastatic sites, and history of brain metastases) on overall survival are reported.
For two subgroups - LDH<=upper limit of normal and brain metastases=yes, the upper limits of the 95% confidence interval were not calculable for the etoposide+carboplatin group - instead the number of participants in these two subgroups are presented as a post-hoc outcome measure.
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baseline to date of death from any cause (up to 19.6 months)
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Progression Free Survival
Időkeret: baseline to measured progressive disease (up to 14.7 months)
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The period from study entry until disease progression, death or date of last contact.
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baseline to measured progressive disease (up to 14.7 months)
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Change From Baseline to Each Cycle in Functional Assessment of Cancer Therapy - Lung (FACT-L)
Időkeret: baseline and 6 cycles (21-day cycles)
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FACT-L measures following domains of health-related quality of life (HR-QL): physical well-being, social/family well-being, emotional well-being, functional well-being, and additional concerns of lung cancer.
Total scores range from 0 to 136, with higher scores representing better HR-QL.
A clinically meaningful change is considered to be 5 points.
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baseline and 6 cycles (21-day cycles)
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Overall Survival (Subgroups: LDH<=Upper Limit of Normal and History of Brain Metastases=Yes)
Időkeret: baseline to date of death due to any cause (up to 19.6 months)
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The effects of individual baseline factors (lactate dehydrogenase (LDH) and history of brain metastases) on overall survival are reported.
The Upper Limits of the 95% Confidence Intervals were not calculable for these factors in the Etoposide+Carboplatin group.
The number of participants in these subgroup are instead presented as a Post-Hoc Outcome Measure.
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baseline to date of death due to any cause (up to 19.6 months)
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Együttműködők és nyomozók
Itt találhatja meg a tanulmányban érintett személyeket és szervezeteket.
Szponzor
Nyomozók
- Tanulmányi igazgató: Call 1-877-CTLILLY(1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST), Eli Lilly and Company
Publikációk és hasznos linkek
A vizsgálattal kapcsolatos információk beviteléért felelős személy önkéntesen bocsátja rendelkezésre ezeket a kiadványokat. Ezek bármiről szólhatnak, ami a tanulmányhoz kapcsolódik.
Tanulmányi rekorddátumok
Ezek a dátumok nyomon követik a ClinicalTrials.gov webhelyre benyújtott vizsgálati rekordok és összefoglaló eredmények benyújtásának folyamatát. A vizsgálati feljegyzéseket és a jelentett eredményeket a Nemzeti Orvostudományi Könyvtár (NLM) felülvizsgálja, hogy megbizonyosodjon arról, hogy megfelelnek-e az adott minőség-ellenőrzési szabványoknak, mielőtt közzéteszik őket a nyilvános weboldalon.
Tanulmány főbb dátumok
Tanulmány kezdete
2006. augusztus 1.
Elsődleges befejezés (Tényleges)
2008. június 1.
A tanulmány befejezése (Tényleges)
2008. június 1.
Tanulmányi regisztráció dátumai
Először benyújtva
2006. augusztus 10.
Először nyújtották be, amely megfelel a minőségbiztosítási kritériumoknak
2006. augusztus 10.
Első közzététel (Becslés)
2006. augusztus 15.
Tanulmányi rekordok frissítései
Utolsó frissítés közzétéve (Becslés)
2009. október 28.
Az utolsó frissítés elküldve, amely megfelel a minőségbiztosítási kritériumoknak
2009. október 20.
Utolsó ellenőrzés
2009. október 1.
Több információ
A tanulmányhoz kapcsolódó kifejezések
További vonatkozó MeSH feltételek
- Légúti betegségek
- Neoplazmák
- Tüdőbetegségek
- Neoplazmák webhelyenként
- Légúti neoplazmák
- Mellkasi neoplazmák
- Karcinóma, bronchogén
- Bronchiális neoplazmák
- Tüdő neoplazmák
- Kissejtes tüdőkarcinóma
- A farmakológiai hatás molekuláris mechanizmusai
- Nukleinsav szintézis gátlók
- Enzim gátlók
- Antineoplasztikus szerek
- Daganatellenes szerek, fitogén
- Topoizomeráz II inhibitorok
- Topoizomeráz gátlók
- Folsav antagonisták
- Carboplatin
- Etoposide
- Pemetrexed
Egyéb vizsgálati azonosító számok
- 9691
- H3E-MC-JMHO
Ezt az információt közvetlenül a clinicaltrials.gov webhelyről szereztük be, változtatás nélkül. Ha bármilyen kérése van vizsgálati adatainak módosítására, eltávolítására vagy frissítésére, kérjük, írjon a következő címre: register@clinicaltrials.gov. Amint a változás bevezetésre kerül a clinicaltrials.gov oldalon, ez a webhelyünkön is automatikusan frissül. .
Klinikai vizsgálatok a Kissejtes tüdőrák
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Jonsson Comprehensive Cancer CenterEli Lilly and Company; Genentech, Inc.ToborzásÁttétes tüdő nem kissejtes karcinóma | Tűzálló tüdő nem kissejtes karcinóma | Stage IV Lung Cancer American Joint Committee on Cancer (AJCC) v8 | IVA stádiumú tüdőrák AJCC v8 | IVB stádiumú tüdőrák AJCC v8Egyesült Államok