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Modeling and Testing Change in Mental Abilities in Childhood

2017年4月14日 更新者:University of Southern California

Modeling and Testing Change in Mental Abilities in Childhood Through Computer-based Interventions

Children with low executive function, working memory and attention skills in childhood not only do poorly at school, but also go on to do poorly on social, health, and financial indicators in adulthood.

The rate of executive function disorders in children is vastly underestimated at 17% , even when taking into account two of the more widely known disorders of Attention Deficit Hyperactivity Disorder (11%) and Fetal Alcohol Spectrum Disorders (6%), but children of lower socioeconomic status are especially vulnerable due to reduced resource availability.

As executive function, working memory and attention skills are central to success in later life, if children with low skills can be given targeted training to improve the skills they fall short on, there is potential to both improve their short-term academic performance, and influence long-term achievement. In fact, poor executive function skills and poor attention and working memory is a large predictor of poor performance even in typically developing children who are doing poorly academically.

Hypothesis 1. Those with lower working memory will also have lower problem solving skills and lower indices of other executive functioning skills such as reasoning/problem solving.

Hypothesis 2. Children that start with lower WM and PS will show the highest gains in training related performance, and such high gains on WM and PS will lead to better performance post-intervention compared to baseline measures of cognitive function.

Hypothesis 3: Those who make the largest gains in WM and PS with training will show more retention of training gains at 6 months compared those who show lower gains.

Aim 1. Assess working memory (WM) and processing speed (PS) skills in children and their inter-relationships with executive functioning skills Aim 2. Examine change in cognitive function in WM and PS after intensive training in WM and PS, during and immediately post-intervention Aim 3. Examine long-term retention of training effects on WM, PS, and executive functions.

The purpose of this study is to establish an effective and targeted working memory and processing speed intervention in children ages 7-10 with low to average executive function skills, by utilizing home-based computer games specifically designed to appeal to children.

Following institution approved consents, 60 low socioeconomic status children from Los Angeles will be recruited and enrolled in the study and be asked to play specific fun, but targeted cognitive computer games for 10 weeks.

The results of this pilot study will establish a protocol for feasibility of improving executive function skills in children with underdeveloped skills and inform on sufficiency of sample sizes, length of interventions, and directly impact computer-based intervention research and cost-effective techniques in children's cognitive development within the next 3-5 years.

研究概览

研究类型

介入性

注册 (实际的)

20

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • California
      • Los Angeles、California、美国、90089
        • University of Southern California

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

7年 至 11年 (孩子)

接受健康志愿者

是的

有资格学习的性别

全部

描述

Inclusion Criteria:

  • Understands and speaks English

Exclusion Criteria:

  • Diagnosed psychological disorder
  • Head trauma with loss of consciousness of >5 minutes

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:基础科学
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:双倍的

武器和干预

参与者组/臂
干预/治疗
实验性的:Computer games to assess change in executive function skills
Children in Intervention group get to train using executive function games at more difficult levels.
Children get access to computer games for 10 weeks for an hour each week.
其他名称:
  • Difficult / Easy games
有源比较器:Easy games as active comparators for executive function skills
Children in Non-intervention group get to play executive function games at an easy level.
Children get access to computer games for 10 weeks for an hour each week.
其他名称:
  • Difficult / Easy games

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Change in working memory skills assessed through Executive Function Battery and NIH ToolBox
大体时间:3 months
Children will be assessed both on Executive Function Battery and the NIH Toolbox battery to examine change in working memory skills.
3 months
Change in processing speed skills assessed through Executive Function Battery and NIH ToolBox
大体时间:3 months
Children will be assessed both on Executive Function Battery and the NIH Toolbox battery to examine change in processing speed skills.
3 months

次要结果测量

结果测量
措施说明
大体时间
Change in school grades in science, reading and math.
大体时间:3-6 months
Parents will be asked for children's school grades at the beginning of the study, during the study, and at the end of the study to assess the effects of the intervention
3-6 months
Change in parent reported behavior as assessed through BRIEF and CBCL questionnaires
大体时间:3-6 months
Parental reports on BRIEF (Behavior Rating Inventory of Executive Function) and CBCL (Child Behavior Checklist) questionnaires will be used to assess change in behavior
3-6 months

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Prapti Gautam, PhD、University of Southern California

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2015年6月1日

初级完成 (实际的)

2016年8月31日

研究完成 (实际的)

2016年8月31日

研究注册日期

首次提交

2015年5月27日

首先提交符合 QC 标准的

2015年6月1日

首次发布 (估计)

2015年6月2日

研究记录更新

最后更新发布 (实际的)

2017年4月18日

上次提交的符合 QC 标准的更新

2017年4月14日

最后验证

2017年4月1日

更多信息

与本研究相关的术语

其他研究编号

  • 15-01767

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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