Measuring the Electrical Properties of Malignant Tissues In Vivo
2018年10月11日 更新者:Sherman Xuegang Xin、Southern Medical University, China
Measuring the Electrical Properties of the Malignant Tissues During Cancer Surgeries
Previously published studies have indicated that there exist difference in electrical properties (EPs), i.e., the conductivity and relative permittivity, between malignant and adjacent normal tissue, which will be useful in the early detection of cancers.
However the EP information mainly based on ex vivo measurement of cancer tissues, and few data in vivo were published.
The purpose of this study is to in vivo measure the electrical properties of the malignant tissues.
研究概览
详细说明
The measurements were safety guaranteed and were conducted during the cancer surgeries.
Before the tissue was excised from the patient,the pathologist assisted the operator (already at the operating room) responsible for the measurement.The measurement of malignant and corresponding normal tissues were both performed.
The tissues for dielectric properties measurement were classified as normal or malignant by the pathologist based on his own expertise and decision criteria (visual inspection, anatomy) and the per-operative histological examination.
The measurements were directly performed on the tissue before excision.The sites of the measured malignant tissues were marked,doubletracked according to the pathological report to make sure the marked sites are malignant.
The patient age and tissue temperature at the time of measurement were recorded.
研究类型
观察性的
注册 (预期的)
50
联系人和位置
本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。
学习地点
-
-
Guangdong
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Guangzhou、Guangdong、中国、510515
- Southern Medical University
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-
参与标准
研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 孩子
- 成人
- 年长者
接受健康志愿者
不
有资格学习的性别
全部
取样方法
概率样本
研究人群
The patients who are diagnosed with cancer disease and about to have an operation to excise the cancer tissues.
描述
Inclusion Criteria:
- Clinical diagnosis of cancer Disease
Exclusion Criteria:
- None
学习计划
本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。
研究是如何设计的?
设计细节
研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
|---|---|
|
Conductivity of the Malignant Tissues measured In Vivo
大体时间:one year
|
one year
|
|
Relative Permittivity of the Malignant Tissues measured In Vivo
大体时间:one year
|
one year
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员:Sherman X Xin, professor、School of Biomedical Engineering,Southern Medical University
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- Surowiec AJ, Stuchly SS, Barr JB, Swarup A. Dielectric properties of breast carcinoma and the surrounding tissues. IEEE Trans Biomed Eng. 1988 Apr;35(4):257-63. doi: 10.1109/10.1374. No abstract available.
- Athey T W, Stuchly M A and Stuchly S S. Measurement of radio frequency permittivity of biological tissues with an open-ended coaxial line: Part I. Microwave Theory and Techniques, IEEE Transactions on IEEE Trans 30(1): 82-86, 1982.
- Bobowski Jake S, Johnson Thomas. Permittivity measurements of biological samples by an open-ended coaxial line. Progress In Electromagnetics Research B 40: 159-183, 2012.
- Smith SR, Foster KR, Wolf GL. Dielectric properties of VX-2 carcinoma versus normal liver tissue. IEEE Trans Biomed Eng. 1986 May;33(5):522-4. doi: 10.1109/TBME.1986.325740. No abstract available.
- Mehta P, Chand K, Narayanswamy D, Beetner D G, Zoughi R and Stoecker W V. Microwave reflectometry as a novel diagnostic tool for detection of skin cancers IEEE Trans. Instrum. Meas. 55: 1309-16, 2006
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (预期的)
2018年12月1日
初级完成 (预期的)
2019年6月1日
研究完成 (预期的)
2020年12月1日
研究注册日期
首次提交
2016年2月22日
首先提交符合 QC 标准的
2016年4月18日
首次发布 (估计)
2016年4月21日
研究记录更新
最后更新发布 (实际的)
2018年10月12日
上次提交的符合 QC 标准的更新
2018年10月11日
最后验证
2018年10月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.