Prediction of Coronary Artery Disease Severity by Epicardial Adipose Tissue Thickness
Predictive Value of Epicardial Fat Thickness for Disease Severity in Coronary Artery Disease Patients
研究概览
详细说明
epicardial adipose tissue is defined as the adipose tissue between the visceral pericardium and the outer margin of the myocardium which can be considered an endocrine organ that secretes pro-inflammatory and anti-inflammatory cytokines and chemokines including adiponectin.as investigators know, inflammatory response is an important factor in the coronary atherogenesis. Therefore,epicardial adipose tissue is likely to be connected with the severity of coronary artery disease.Recent studies showed that the thickness of the epicardial adipose tissue in patients with coronary artery disease was greater than that with normal coronary arteries.
epicardial adipose tissue will be assessed using transthoracic echocardiography and cardiac magnetic resonance which allows for an accurate volumetric quantification of epicardial fat.
研究类型
注册 (预期的)
联系人和位置
学习地点
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Single
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Assiut、Single、埃及
- 招聘中
- Jacqueline George
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接触：
- hosam hassan, professor doctor
- 电话号码：01223971327
- 邮箱：hosam_hasan@hotmail.com
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接触：
- heba el nagar, lecturer
- 电话号码：01001963100
- 邮箱：Heba_M_elnagar@yahoo.com
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria
- Normal thoracic shape
- Sinus rhythm
- without severe respiratory diseases
Exclusion Criteria:
- contraindication for cardiac magnetic resonance.
- Patients who previously underwent coronary artery bypass grafting or percutaneous coronary angiography prior to admission
- history of chronic kidney disease with glomerular filtration rate <30 mL/min
- pericardial and/or pleural effusion.
学习计划
研究是如何设计的？
设计细节
- 观测模型：病例对照
- 时间观点：横截面
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
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myocardial infarction patients
transthoracic echocardiography and cardiac magnetic resonance
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transthoracic echocardiography and magnetic resonance imaging of the heart
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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measurement of epicardial adipose tissue as marker of severity of coronary artery disease in myocardial infarction patients.
大体时间：one year
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epicardial adipose tissue measurement using transthoracic echocardiography and cardiac magnetic resonance
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one year
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合作者和调查者
赞助
出版物和有用的链接
研究记录日期
研究主要日期
学习开始 (预期的)
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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