Following the Sound of Music
2026年8月14日 更新者：Susanne Jaeggi、Northeastern University
Comparing the Effects of Music vs. Non-Music Based Interventions on Auditory and Cognitive Processing in Older Adults
The proposed study will enroll healthy older adult participants to examine the effectiveness of music listening activities to promote hearing and cognition.
Participants will be randomized into one of four experimental groups and can expect to participate for up to 21 hours of research distributed over 20 weeks.
研究概览
地位
招聘中
研究类型
介入性
注册 (估计的)
216
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习联系方式
- 姓名：Audrey Carrillo, MA
- 电话号码：626-482-8091
- 邮箱：a.carrillo@northeastern.edu
学习地点
-
-
Massachusetts
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Boston、Massachusetts、美国、02115
- 招聘中
- Northeastern University
-
接触：
- Audrey Carrillo, MA
- 电话号码：626-482-8091
- 邮箱：a.carrillo@northeastern.edu
-
-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
是的
描述
Inclusion Criteria:
- Age: 60+
- No self-reported auditory difficulties and normal or near-normal hearing sensitivity as measured by SRTs.
- Should have no more than typical hearing loss for their age and no evidence of dementia.
- Fluent in English and/or Spanish
- No more than two years of formal music training in childhood OR in the past 20 years
Exclusion Criteria:
- Abnormal vision or hearing prohibitive of training
- History of seizures, focal brain lesion, or head injury with loss of consciousness
- Physical handicap (motor or perceptual) that would impede training procedures
- Social, educational or economic hardship prohibitive to training schedule Concurrent enrollment in other cognitive training studies
- History of major psychiatric illness, including psychosis, bipolar disorder, depression, alcohol or substance abuse, recent bereavement
- Geriatric Depression Scale-15 (GDS-15) score of 6 or higher, indicating clinically significant depressive symptoms
- Not being proficient enough in English or Spanish that would prevent following and understanding all instructions and completing all testing sessions
- Diagnosis of dementia or other neurological disease, including mild cognitive impairment (MCI)
- Telephone-Montreal Cognitive Assessment (t-MoCA) score of 16 or less
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：基础科学
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：双倍的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Sound of Music Plus Attention
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Participants will listen to musical excerpts, and guided instructions will be provided to tell the participants what aspect of the music to pay attention to and how to respond.
Participants will log responses on an interactive tablet-based interface.
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实验性的：Sound of Music
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Participants will listen to musical excerpts and will be provided with guided instructions directing their attention to specific aspects of the music.
Participants will report when they perceive a noticeable change in the music (e.g., changes in instrumentation, rhythm, texture, or intensity).
Participants will log responses on an interactive tablet-based interface.
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实验性的：Sound of Tones Plus Attention
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Participants will be asked to attend to auditory stimuli and respond to them according to guided instructions.
Participants will log responses on an interactive tablet-based interface.
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无干预：Business as usual Control
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Digits-in-Noise Task
大体时间：Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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The Digits-in-Noise (DIN) test presents trials of three sequential spoken digits against a broad-band, speech-shaped masker.
Signal/noise ratio is varied adaptively to track 50% correct.
The dependent variable is the threshold noise tolerance in dB.
Lower scores indicate better performance.
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Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Spatial Release From Masking Task
大体时间：Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Tests the ability to distinguish speech from competing speech.
Collocated condition uses target and two competing maskers all located directly in front of the listener, and spatially separated condition uses two masking sentences sent from 45 degrees to the left and right of center.
Sentences are correctly identified as part of a series of test trials in which TMR progressively reduced every two trials.
The dependent variable is the threshold target-to-masker ratio (TMR) as estimated based on the number of sentences correctly identified.
Lower scores indicate better performance.
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Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Dichotic Sentence Identification Task
大体时间：Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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The DSI test simultaneously presents two nonsense sentences, one to each ear.
Participants indicate two sentences heard from a list of alternatives.
DSI sentences are presented at a comfortable listening level, usually 50 dB above pure-tone average of each ear.
The dependent variable is the percentage of sentences correctly identified.
Higher scores indicate better performance.
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Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Revised Hearing Handicap Inventory for the Elderly (RHHI)
大体时间：Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
|
Survey that assesses the perceived level of hearing ability under different environmental or social situations, and participants also self-report ear surgeries or known ear pathologies.
The dependent variable is total score (summed).
Higher scores indicate greater perceived handicap.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Speech Recognition Threshold using Coordinate Response Measure
大体时间：Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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SRT stimuli from the Coordinate Response Measure are sentences that participants hear that contain a color and number (e.g., "Ready Charlie, go to blue three now").
Participants select one of 36 colored/numbered squares that matches the color-number combination of the sentence.
The dependent variable is the threshold target-to-masker ratio (TMR) as estimated based on the number of sentences correctly identified as part of a series of 20 test trials in which TMR progressively reduced every two trials.
Lower scores indicate better performance.
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Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Gap Detection Task
大体时间：Pre-test (week 1), Post-test (week 10)
|
Temporal sensitivity to silent gaps between pairs of brief (4 ms) bandlimited stimuli.
The gap duration will start at 6 ms, and be reduced from there using a staircase procedure.
The dependent variable is the threshold (in ms) at which participants stop responding accurately.
Lower scores indicate better performance.
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Pre-test (week 1), Post-test (week 10)
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Spectrotemporal Sensitivity Task
大体时间：Pre-test (week 1), Post-test (week 10)
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Stimuli are either unmodulated or are spectrotemporally modulated in amplitude using two cycles/octave for the spectral modulation and 4 Hz for the temporal modulation.
Modulation depth in decibels (dB) will be adaptively varied to estimate threshold.
The dependent variable is the threshold (in dB) at which participants stop responding accurately.
Lower scores indicate better performance.
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Pre-test (week 1), Post-test (week 10)
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Monaural and Binaural Sensitivity to Frequency Modulation Task
大体时间：Pre-test (week 1), Post-test (week 10)
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The stimulus is a pure tone that is modulated sinusoidally and varies at a rate of 2 Hz.
The task is to detect differences between modulated and unmodulated tones, and the modulated "depth" in Hz is tracked adaptively.
The BFM stimuli are identical to MFM except for presentation to both ears with increasing frequency in one ear and decreasing in the other.
The dependent variable is the threshold (in Hz) at which participants stop responding accurately.
Lower scores indicate better performance.
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Pre-test (week 1), Post-test (week 10)
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Audio Visual Divided Attention Task
大体时间：Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
|
Participants are presented with auditory sequences of spoken digits and visual sequences of written letters.
Participants will be instructed to recall a particular sequence either in advance (assesses selective attention) or only afterwards (assesses divided attention).
The dependent variable is the fall-off of reaction time and accuracy across a the single-stream task.
Higher scores indicate better performance.
|
Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Paced Serial Addition Task
大体时间：Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Participants are shown a series of numbers one at a time.
Their goal is to add the last two numbers presented and select the answer that correctly adds the two numbers.
Participants are shown single digit numbers and are required to answer on a number pad .
The dependent variable is the total number of correct responses.
Higher scores indicate better performance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Letter-Number Sequencing Task
大体时间：Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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The participant is presented with a mixed order of letters and numbers and must remember and sort them numerically and alphabetically.
Set size starts at 2 and increases until the participants fail to recall both trials at a given set size.
The dependent variable is Score (total number of correct trials).
Higher scores indicate better performance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Auditory N-back Task
大体时间：Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Participants are presented with a consecutive stream of tones through headphones, and are asked to tap on the screen every time the currently presented item matches the one presented N items earlier.
The dependent variable consists of accuracy on each of the levels calculated as hits/(hits+misses+false alarms).
Higher scores indicate better performance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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其他结果措施
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
POMS 2-A
大体时间：Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
|
Self report measure assessing current mood states in adults.
Participants rate descriptive mood words according to how they feel during the specified assessment timeframe using a 5-point response scale.
The dependent variable is Total Mood Disturbance (TMD) score, with higher values indicating greater overall mood disturbance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Ryff's Scale of Psychological Well-being Score
大体时间：Pre-test (week 1), Follow-up (week 18), Follow-up (week 18)
|
Self-report questionnaire that assesses six domains of well-being (self-acceptance, environmental mastery, positive relations, purpose in life, personal growth, and autonomy).
Higher scores indicate greater perceived well-being.
|
Pre-test (week 1), Follow-up (week 18), Follow-up (week 18)
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Short Warwick-Edinburgh Mental Wellbeing Scale (SWEMWBS)
大体时间：Pre-test (week 1), Follow-up (week 18), Follow-up (week 18)
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A 7-item self-report measure assessing positive mental well-being.
Participants rate statements about their thoughts and feelings over the specified assessment period using a 5-point response scale.
The dependent variable is the total well-being score, with higher values indicating greater mental well-being.
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Pre-test (week 1), Follow-up (week 18), Follow-up (week 18)
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Musicality Survey
大体时间：Pre-test (week 1), Follow-up (week 18)
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Self-report survey of participants' past musical experiences, with items including the Active Engagement, Perceptual Abilities, and Emotions factors from the Goldsmith's Music Sophistication Index, the Absorption factor from the Extended Barcelona Music Reward Questionnaire, and selected items from the Ollen Music Sophistication Index.
Higher scores indicate greater self-reported musical involvement and ability.
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Pre-test (week 1), Follow-up (week 18)
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Short-Musical Ear Test
大体时间：Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Participants will listen to a series of short rhythmic and melodic sequences and determine whether each pair is identical or different from one another.
The dependent variable is percentage correct.
Higher scores indicate better performance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Older Adult Cognitive Battery
大体时间：Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
|
This digitally administered battery includes a word list learning and complex figure drawing task, a revised version of the Boston Naming Task, a vocabulary task (Shipley), the Trail Making Task (parts A and B), and an older-adult version of the University of California Matrix Reasoning Task.
The dependent variables are percentage correct for Boston Naming Shipley, and Matrix Reasoning where, higher scores indicate better performance.
For the Trail Making Task, the dependent variable is the time difference between parts A and B, and lower scores indicate better performance.
For the word-list learning task, the dependent variable is the total number of words correctly recalled across the learning trials, with higher values indicating better performance.
For the complex figure task, the dependent variable is the total accuracy score based on correctly reproduced figure elements, with higher values indicating better performance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Susanne Jaeggi, PhD、Northeastern University
- 首席研究员：Aaron Seitz, PhD、Northeastern University
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (估计的)
2026年8月14日
初级完成 (估计的)
2027年5月31日
研究完成 (估计的)
2027年8月31日
研究注册日期
首次提交
2026年8月14日
首先提交符合 QC 标准的
2026年8月14日
首次发布 (实际的)
2026年8月19日
研究记录更新
最后更新发布 (实际的)
2026年8月19日
上次提交的符合 QC 标准的更新
2026年8月14日
最后验证
2026年8月1日
更多信息
与本研究相关的术语
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
是的
IPD 计划说明
All individual participant data (anonymized)
IPD 共享时间框架
Data will be available persistently at the conclusion of the study.
IPD 共享访问标准
There are no access criteria.
IPD 共享支持信息类型
- 树液
- 国际碳纤维联合会
药物和器械信息、研究文件
研究美国 FDA 监管的药品
不
研究美国 FDA 监管的设备产品
不
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.