Following the Sound of Music
14 августа 2026 г. обновлено: Susanne Jaeggi, Northeastern University
Comparing the Effects of Music vs. Non-Music Based Interventions on Auditory and Cognitive Processing in Older Adults
The proposed study will enroll healthy older adult participants to examine the effectiveness of music listening activities to promote hearing and cognition.
Participants will be randomized into one of four experimental groups and can expect to participate for up to 21 hours of research distributed over 20 weeks.
Обзор исследования
Статус
Рекрутинг
Тип исследования
Интервенционный
Регистрация (Оцененный)
216
Фаза
- Непригодный
Контакты и местонахождение
В этом разделе приведены контактные данные лиц, проводящих исследование, и информация о том, где проводится это исследование.
Контакты исследования
- Имя: Audrey Carrillo, MA
- Номер телефона: 626-482-8091
- Электронная почта: a.carrillo@northeastern.edu
Места учебы
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Massachusetts
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Boston, Massachusetts, Соединенные Штаты, 02115
- Рекрутинг
- Northeastern University
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Контакт:
- Audrey Carrillo, MA
- Номер телефона: 626-482-8091
- Электронная почта: a.carrillo@northeastern.edu
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Критерии участия
Исследователи ищут людей, которые соответствуют определенному описанию, называемому критериям приемлемости. Некоторыми примерами этих критериев являются общее состояние здоровья человека или предшествующее лечение.
Критерии приемлемости
Возраст, подходящий для обучения
- Взрослый
- Пожилой взрослый
Принимает здоровых добровольцев
Да
Описание
Inclusion Criteria:
- Age: 60+
- No self-reported auditory difficulties and normal or near-normal hearing sensitivity as measured by SRTs.
- Should have no more than typical hearing loss for their age and no evidence of dementia.
- Fluent in English and/or Spanish
- No more than two years of formal music training in childhood OR in the past 20 years
Exclusion Criteria:
- Abnormal vision or hearing prohibitive of training
- History of seizures, focal brain lesion, or head injury with loss of consciousness
- Physical handicap (motor or perceptual) that would impede training procedures
- Social, educational or economic hardship prohibitive to training schedule Concurrent enrollment in other cognitive training studies
- History of major psychiatric illness, including psychosis, bipolar disorder, depression, alcohol or substance abuse, recent bereavement
- Geriatric Depression Scale-15 (GDS-15) score of 6 or higher, indicating clinically significant depressive symptoms
- Not being proficient enough in English or Spanish that would prevent following and understanding all instructions and completing all testing sessions
- Diagnosis of dementia or other neurological disease, including mild cognitive impairment (MCI)
- Telephone-Montreal Cognitive Assessment (t-MoCA) score of 16 or less
Учебный план
В этом разделе представлена подробная информация о плане исследования, в том числе о том, как планируется исследование и что оно измеряет.
Как устроено исследование?
Детали дизайна
- Основная цель: Фундаментальная наука
- Распределение: Рандомизированный
- Интервенционная модель: Параллельное назначение
- Маскировка: Двойной
Оружие и интервенции
Группа участников / Армия |
Вмешательство/лечение |
|---|---|
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Экспериментальный: Sound of Music Plus Attention
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Participants will listen to musical excerpts, and guided instructions will be provided to tell the participants what aspect of the music to pay attention to and how to respond.
Participants will log responses on an interactive tablet-based interface.
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Экспериментальный: Sound of Music
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Participants will listen to musical excerpts and will be provided with guided instructions directing their attention to specific aspects of the music.
Participants will report when they perceive a noticeable change in the music (e.g., changes in instrumentation, rhythm, texture, or intensity).
Participants will log responses on an interactive tablet-based interface.
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Экспериментальный: Sound of Tones Plus Attention
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Participants will be asked to attend to auditory stimuli and respond to them according to guided instructions.
Participants will log responses on an interactive tablet-based interface.
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Без вмешательства: Business as usual Control
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Что измеряет исследование?
Первичные показатели результатов
Мера результата |
Мера Описание |
Временное ограничение |
|---|---|---|
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Digits-in-Noise Task
Временное ограничение: Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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The Digits-in-Noise (DIN) test presents trials of three sequential spoken digits against a broad-band, speech-shaped masker.
Signal/noise ratio is varied adaptively to track 50% correct.
The dependent variable is the threshold noise tolerance in dB.
Lower scores indicate better performance.
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Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Spatial Release From Masking Task
Временное ограничение: Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Tests the ability to distinguish speech from competing speech.
Collocated condition uses target and two competing maskers all located directly in front of the listener, and spatially separated condition uses two masking sentences sent from 45 degrees to the left and right of center.
Sentences are correctly identified as part of a series of test trials in which TMR progressively reduced every two trials.
The dependent variable is the threshold target-to-masker ratio (TMR) as estimated based on the number of sentences correctly identified.
Lower scores indicate better performance.
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Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Dichotic Sentence Identification Task
Временное ограничение: Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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The DSI test simultaneously presents two nonsense sentences, one to each ear.
Participants indicate two sentences heard from a list of alternatives.
DSI sentences are presented at a comfortable listening level, usually 50 dB above pure-tone average of each ear.
The dependent variable is the percentage of sentences correctly identified.
Higher scores indicate better performance.
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Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Вторичные показатели результатов
Мера результата |
Мера Описание |
Временное ограничение |
|---|---|---|
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Revised Hearing Handicap Inventory for the Elderly (RHHI)
Временное ограничение: Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Survey that assesses the perceived level of hearing ability under different environmental or social situations, and participants also self-report ear surgeries or known ear pathologies.
The dependent variable is total score (summed).
Higher scores indicate greater perceived handicap.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Speech Recognition Threshold using Coordinate Response Measure
Временное ограничение: Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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SRT stimuli from the Coordinate Response Measure are sentences that participants hear that contain a color and number (e.g., "Ready Charlie, go to blue three now").
Participants select one of 36 colored/numbered squares that matches the color-number combination of the sentence.
The dependent variable is the threshold target-to-masker ratio (TMR) as estimated based on the number of sentences correctly identified as part of a series of 20 test trials in which TMR progressively reduced every two trials.
Lower scores indicate better performance.
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Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Gap Detection Task
Временное ограничение: Pre-test (week 1), Post-test (week 10)
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Temporal sensitivity to silent gaps between pairs of brief (4 ms) bandlimited stimuli.
The gap duration will start at 6 ms, and be reduced from there using a staircase procedure.
The dependent variable is the threshold (in ms) at which participants stop responding accurately.
Lower scores indicate better performance.
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Pre-test (week 1), Post-test (week 10)
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Spectrotemporal Sensitivity Task
Временное ограничение: Pre-test (week 1), Post-test (week 10)
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Stimuli are either unmodulated or are spectrotemporally modulated in amplitude using two cycles/octave for the spectral modulation and 4 Hz for the temporal modulation.
Modulation depth in decibels (dB) will be adaptively varied to estimate threshold.
The dependent variable is the threshold (in dB) at which participants stop responding accurately.
Lower scores indicate better performance.
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Pre-test (week 1), Post-test (week 10)
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Monaural and Binaural Sensitivity to Frequency Modulation Task
Временное ограничение: Pre-test (week 1), Post-test (week 10)
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The stimulus is a pure tone that is modulated sinusoidally and varies at a rate of 2 Hz.
The task is to detect differences between modulated and unmodulated tones, and the modulated "depth" in Hz is tracked adaptively.
The BFM stimuli are identical to MFM except for presentation to both ears with increasing frequency in one ear and decreasing in the other.
The dependent variable is the threshold (in Hz) at which participants stop responding accurately.
Lower scores indicate better performance.
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Pre-test (week 1), Post-test (week 10)
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Audio Visual Divided Attention Task
Временное ограничение: Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Participants are presented with auditory sequences of spoken digits and visual sequences of written letters.
Participants will be instructed to recall a particular sequence either in advance (assesses selective attention) or only afterwards (assesses divided attention).
The dependent variable is the fall-off of reaction time and accuracy across a the single-stream task.
Higher scores indicate better performance.
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Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
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Paced Serial Addition Task
Временное ограничение: Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Participants are shown a series of numbers one at a time.
Their goal is to add the last two numbers presented and select the answer that correctly adds the two numbers.
Participants are shown single digit numbers and are required to answer on a number pad .
The dependent variable is the total number of correct responses.
Higher scores indicate better performance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Letter-Number Sequencing Task
Временное ограничение: Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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The participant is presented with a mixed order of letters and numbers and must remember and sort them numerically and alphabetically.
Set size starts at 2 and increases until the participants fail to recall both trials at a given set size.
The dependent variable is Score (total number of correct trials).
Higher scores indicate better performance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Auditory N-back Task
Временное ограничение: Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Participants are presented with a consecutive stream of tones through headphones, and are asked to tap on the screen every time the currently presented item matches the one presented N items earlier.
The dependent variable consists of accuracy on each of the levels calculated as hits/(hits+misses+false alarms).
Higher scores indicate better performance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Другие показатели результатов
Мера результата |
Мера Описание |
Временное ограничение |
|---|---|---|
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POMS 2-A
Временное ограничение: Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Self report measure assessing current mood states in adults.
Participants rate descriptive mood words according to how they feel during the specified assessment timeframe using a 5-point response scale.
The dependent variable is Total Mood Disturbance (TMD) score, with higher values indicating greater overall mood disturbance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Ryff's Scale of Psychological Well-being Score
Временное ограничение: Pre-test (week 1), Follow-up (week 18), Follow-up (week 18)
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Self-report questionnaire that assesses six domains of well-being (self-acceptance, environmental mastery, positive relations, purpose in life, personal growth, and autonomy).
Higher scores indicate greater perceived well-being.
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Pre-test (week 1), Follow-up (week 18), Follow-up (week 18)
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Short Warwick-Edinburgh Mental Wellbeing Scale (SWEMWBS)
Временное ограничение: Pre-test (week 1), Follow-up (week 18), Follow-up (week 18)
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A 7-item self-report measure assessing positive mental well-being.
Participants rate statements about their thoughts and feelings over the specified assessment period using a 5-point response scale.
The dependent variable is the total well-being score, with higher values indicating greater mental well-being.
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Pre-test (week 1), Follow-up (week 18), Follow-up (week 18)
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Musicality Survey
Временное ограничение: Pre-test (week 1), Follow-up (week 18)
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Self-report survey of participants' past musical experiences, with items including the Active Engagement, Perceptual Abilities, and Emotions factors from the Goldsmith's Music Sophistication Index, the Absorption factor from the Extended Barcelona Music Reward Questionnaire, and selected items from the Ollen Music Sophistication Index.
Higher scores indicate greater self-reported musical involvement and ability.
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Pre-test (week 1), Follow-up (week 18)
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Short-Musical Ear Test
Временное ограничение: Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Participants will listen to a series of short rhythmic and melodic sequences and determine whether each pair is identical or different from one another.
The dependent variable is percentage correct.
Higher scores indicate better performance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Older Adult Cognitive Battery
Временное ограничение: Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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This digitally administered battery includes a word list learning and complex figure drawing task, a revised version of the Boston Naming Task, a vocabulary task (Shipley), the Trail Making Task (parts A and B), and an older-adult version of the University of California Matrix Reasoning Task.
The dependent variables are percentage correct for Boston Naming Shipley, and Matrix Reasoning where, higher scores indicate better performance.
For the Trail Making Task, the dependent variable is the time difference between parts A and B, and lower scores indicate better performance.
For the word-list learning task, the dependent variable is the total number of words correctly recalled across the learning trials, with higher values indicating better performance.
For the complex figure task, the dependent variable is the total accuracy score based on correctly reproduced figure elements, with higher values indicating better performance.
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Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
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Соавторы и исследователи
Здесь вы найдете людей и организации, участвующие в этом исследовании.
Спонсор
Следователи
- Главный следователь: Susanne Jaeggi, PhD, Northeastern University
- Главный следователь: Aaron Seitz, PhD, Northeastern University
Даты записи исследования
Эти даты отслеживают ход отправки отчетов об исследованиях и сводных результатов на сайт ClinicalTrials.gov. Записи исследований и сообщаемые результаты проверяются Национальной медицинской библиотекой (NLM), чтобы убедиться, что они соответствуют определенным стандартам контроля качества, прежде чем публиковать их на общедоступном веб-сайте.
Изучение основных дат
Начало исследования (Оцененный)
14 августа 2026 г.
Первичное завершение (Оцененный)
31 мая 2027 г.
Завершение исследования (Оцененный)
31 августа 2027 г.
Даты регистрации исследования
Первый отправленный
14 августа 2026 г.
Впервые представлено, что соответствует критериям контроля качества
14 августа 2026 г.
Первый опубликованный (Действительный)
19 августа 2026 г.
Обновления учебных записей
Последнее опубликованное обновление (Действительный)
19 августа 2026 г.
Последнее отправленное обновление, отвечающее критериям контроля качества
14 августа 2026 г.
Последняя проверка
1 августа 2026 г.
Дополнительная информация
Термины, связанные с этим исследованием
Ключевые слова
Другие идентификационные номера исследования
- 26-06-08
Планирование данных отдельных участников (IPD)
Планируете делиться данными об отдельных участниках (IPD)?
ДА
Описание плана IPD
All individual participant data (anonymized)
Сроки обмена IPD
Data will be available persistently at the conclusion of the study.
Критерии совместного доступа к IPD
There are no access criteria.
Совместное использование IPD Поддерживающий тип информации
- САП
- МКФ
Информация о лекарствах и устройствах, исследовательские документы
Изучает лекарственный продукт, регулируемый FDA США.
Нет
Изучает продукт устройства, регулируемый Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов США.
Нет
Эта информация была получена непосредственно с веб-сайта clinicaltrials.gov без каких-либо изменений. Если у вас есть запросы на изменение, удаление или обновление сведений об исследовании, обращайтесь по адресу register@clinicaltrials.gov. Как только изменение будет реализовано на clinicaltrials.gov, оно будет автоматически обновлено и на нашем веб-сайте. .