Evaluation of an AI-Assisted Tool for CLABSI Surveillance at VA Medical Centers (VA-AI-CLABSI)
VA National AI Initiative (NAII) Evaluation of an AI-Assisted CLABSI Surveillance Tool: A Prospective Cluster-Randomized Trial
Infection prevention and control programs at US hospitals perform surveillance to detect and publicly report hospital-onset central line-associated bloodstream infections (CLABSI) using standards set by CDC's National Healthcare Safety Network (NHSN). Because this process requires time-consuming review of the medical record by dedicated infection preventionists, VA has developed a generative artificial intelligence (AI) tool that applies the NHSN CLABSI standard to clinical data from the medical record. In this quality improvement initiative, we will evaluate the tool as it is implemented operationally across a cohort of VA medical centers in 3 randomized waves. The purpose of this evaluation is (1) to determine whether the tool reduces the time required for CLABSI surveillance, (2) to assess the objectivity and trustworthiness of the tool from the perspective of infection preventionists, and (3) to detect patient safety events.
研究概览
详细说明
This study is being conducted from a VA operational perspective as quality improvement. This will proceed regardless of research approvals. This was submitted to the University of Maryland / Baltimore VA joint IRB/VA Research & Development committees and determined to be non-human subjects research.
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名：Jonathan D Baghdadi, MD, PhD
- 电话号码：410-706-0066
- 邮箱：jbaghdadi@som.umaryland.edu
研究联系人备份
- 姓名：Daniel J Morgan, MD, MS
- 电话号码：410-706-0066
- 邮箱：dmorgan@som.umaryland.edu
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Infection preventionists will participate in this study if their VA medical center is eligible based on the inclusion and exclusion criteria below. At participating sites, all positive blood culture events reviewed as potential central line-associated bloodstream infections (CLABSI) during the study period will be included in the analysis.
Inclusion Criteria:
- VA medical center that provides short- or long-term acute care
- CLABSI surveillance is performed by a local infection prevention team who agree to complete all study assessments
Exclusion Criteria:
1. VA medical center planned for conversion to the Cerner electronic health record within the anticipated study period
学习计划
研究是如何设计的？
设计细节
- 主要用途：卫生服务研究
- 分配：随机化
- 介入模型：交叉作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：Post-implementation of an AI for CLABSI surveillance
Infection preventionists (reviewers) at participating VA medical centers will use the generative artificial intelligence (AI) tool while reviewing cases of bacteremia to adjudicate the presence of a central line-associated bloodstream infection (CLABSI). The tool operationalizes the CDC's National Healthcare Safety Network definition of CLABSI as discrete steps. Reviewers will be allowed to flexibly implement the tool within their workflow, will not be restricted from performing independent review of the medical record to clarify tool output when necessary, and will retain final authority regarding all CLABSI determinations for event reporting. |
The intervention involves implementation of a generative artificial intelligence (AI) tool that operationalizes the CDC National Healthcare Safety Network definition for central line-associated bloodstream infections (CLABSI) to support CLABSI surveillance. The tool reviews the medical record to confirm the presence and duration of a central line, identify competing or secondary sources of infection, exclude commensal organisms and bloodstream infections due to mucosal barrier injury, and provide supporting quotations from the medical record. |
|
无干预：Standard CLABSI surveillance
Infection preventionists at participating VA medical centers will use their pre-intervention approach to surveillance for central line-associated bloodstream infections (CLABSI), which involves manual review of the medical record and reporting per the CDC National Healthcare Safety Network CLABSI definition. |
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Time per bacteremia case review
大体时间：At completion of each bacteremia case review performed during the study period beginning 1 month prior to implementation until 6 months post-implementation.
|
Time in elapsed minutes captured automatically by start and end time of the per-case review form. Assessed at time of completion of the bacteremia case review. |
At completion of each bacteremia case review performed during the study period beginning 1 month prior to implementation until 6 months post-implementation.
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Difficulty of bacteremia case review
大体时间：At completion of each bacteremia case review performed during the study period beginning 1 month prior to implementation until 6 months post-implementation.
|
Measured using the Single Ease Question, a validated single-item 7-level scale. |
At completion of each bacteremia case review performed during the study period beginning 1 month prior to implementation until 6 months post-implementation.
|
|
Objectivity of case review
大体时间：At completion of each bacteremia case review performed during the study period beginning 1 month prior to implementation until 6 months post-implementation.
|
Measured using a question on the case review form ("How objective is the case to review? (1=not at all objective to 7=very objective)"). |
At completion of each bacteremia case review performed during the study period beginning 1 month prior to implementation until 6 months post-implementation.
|
|
Reviewer confidence in case review
大体时间：At completion of each bacteremia case review performed during the study period beginning 1 month prior to implementation until 6 months post-implementation.
|
Measured using a question on the case review form ("How confident are you with your review of this case? (1=not confident to 7=very confident)"). |
At completion of each bacteremia case review performed during the study period beginning 1 month prior to implementation until 6 months post-implementation.
|
|
Infection preventionist-identified safety problems
大体时间：Assessed monthly during each facility's 6-month post-implementation period
|
Reported using a binary question (yes/no) on the monthly survey administered to all sites during the post-implementation period. |
Assessed monthly during each facility's 6-month post-implementation period
|
|
Infection preventionist-identified direct patient harm
大体时间：Assessed monthly during each facility's 6-month post-implementation period
|
Reported using a binary question (yes/no) on the monthly survey administered to all sites during the post-implementation period. |
Assessed monthly during each facility's 6-month post-implementation period
|
合作者和调查者
调查人员
- 首席研究员：Daniel J Morgan, MD, MS、University of Maryland, Baltimore
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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