- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00131001
CARMEDAS: Cost-Effectiveness Analysis of Imaging Strategies in Symptomatic Carotid Stenosis
Cost-Effectiveness Analysis of Imaging Strategies in Symptomatic Carotid Stenosis
PURPOSE: The purpose of this clinical trial is to study the cost-effectiveness ratios of diagnostic strategies for the imaging assessment of symptomatic carotid stenosis.
MATERIALS AND METHODS: The diagnostic accuracies of Doppler ultrasound (DUS), contrast-enhanced magnetic resonance angiography (CEMRA) and computed tomography angiography (CTA) were compared with digital subtraction angiography (DSA) in a multicenter study (CARMEDAS; 206 patients assessable) and in a meta-analysis (for CEMRA and CTA). The direct costs of each imaging method were calculated in 2 university medical centers. Eight hypothetical models were studied with DUS considered as the first-line imaging method and either CEMRA or CTA or DSA as the second or third line method. The effectiveness criterion was the number of potential avoided strokes for each strategy and for 1000 patients.
Study Overview
Status
Conditions
Intervention / Treatment
Study Type
Enrollment
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
-
Bron, France, 69677
- Hopital Louis Pradel
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
Carotid artery stenosis > 50%
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Diagnostic
- Allocation: Non-Randomized
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
---|
To study the cost-effectiveness ratios of diagnostic strategies for the imaging assessment of symptomatic carotid stenosis
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Philippe DOUEK, MD, Hospices Civils de Lyon
Study record dates
Study Major Dates
Study Start
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 99.203
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Carotid Stenosis
-
Heinrich-Heine University, DuesseldorfRecruitingCarotid Artery Plaque | Carotid Artery Diseases | Carotid Artery Stenosis Asymptomatic | Carotid Artery StenosisGermany
-
Xuanwu Hospital, BeijingChanghai Hospital; Peking Union Medical College Hospital; The Second Hospital... and other collaboratorsRecruitingCarotid Artery Stenting | Carotid Endarterectomy | Best Medical Treatment | Carotid Artery Stenosis AsymptomaticChina
-
Xuanwu Hospital, BeijingRecruitingRadiation-induced Carotid Artery StenosisChina
-
Centre Hospitalier St AnneHôpitaux Universitaires Paris Ile-de-Franc OuestNot yet recruiting
-
Ochsner Health SystemWithdrawnTCD | Symptomatic Carotid Stenosis | Asymptomatic Carotid Stenosis | HITSUnited States
-
University of BolognaActive, not recruiting
-
W.L.Gore & AssociatesCompleted
-
Washington University School of MedicineNational Heart, Lung, and Blood Institute (NHLBI); Cedars-Sinai Medical Center and other collaboratorsRecruitingCarotid Atherosclerosis | Asymptomatic Carotid Artery Stenosis | Carotid Artery AtheromaUnited States
-
Mayo ClinicRecruitingPatients With Any Degree of Carotid Artery Stenosis and Vulnerable Features in the Carotid Artery PlaqueUnited States
-
Aesculap AGEnrolling by invitationCarotid Artery Stenosis | Iliac Artery Stenosis | Femoral Artery StenosisGermany
Clinical Trials on contrast-enhanced magnetic resonance angiography
-
Johns Hopkins UniversityCanon Medical Systems, USAActive, not recruitingMagnetic Resonance AngiographyUnited States
-
Sichuan Provincial People's HospitalNot yet recruiting
-
Mario Negri Institute for Pharmacological ResearchEC-DG ResearchCompleted
-
University of CincinnatiActive, not recruiting
-
Vanderbilt-Ingram Cancer CenterNational Cancer Institute (NCI)CompletedBreast CancerUnited States
-
Rutgers, The State University of New JerseyNational Cancer Institute (NCI); Rutgers Cancer Institute of New JerseyActive, not recruitingStage III Renal Cell Cancer | Stage IV Renal Cell Cancer | Stage I Renal Cell Cancer | Stage II Renal Cell CancerUnited States
-
Mario Negri Institute for Pharmacological ResearchAarhus University Hospital; Heidelberg University; Clinica Universidad de Navarra...RecruitingHealthy | Chronic Kidney DiseasesSpain, Denmark, Germany, Italy
-
Yale UniversityTerminatedGlioblastoma MultiformeUnited States
-
American College of Radiology Imaging NetworkNational Cancer Institute (NCI)CompletedBreast CancerUnited States
-
Vanderbilt-Ingram Cancer CenterNational Cancer Institute (NCI)TerminatedUnspecified Adult Solid Tumor, Protocol Specific | Tumors Metastatic to BrainUnited States