Transcranial and Rapid Magnetic Stimulation for Gait Apraxia Due to Normal Pressure Hydrocephalus and Cerebral Ischemia

June 28, 2007 updated by: Devathasan Neurology Practice Pte Ltd
The investigator(neurologist) has published a study in International Congress Series, in the 15th International Conference of Biomagnetism Vancouver Proceedings 2006,and Science Direct website, of 15 patients with brain ischemia and dilated ventricles who improve when treated with transcranial monitoring or low ultrasound wave intensity (milliwatts) and with rapid magnetic stimulation which is also a diagnostic tool routinely used by many neurophysiologists. Before, these patients will progress and may need a brain shunt called Ventriculo-peritoneal shunt. He and collaborators now would like to do a double study as this appears to be a cheap and effective alternative treatment and help patients to walk again.

Study Overview

Status

Unknown

Conditions

Detailed Description

The transcranial monitoring intensity would be equivalent to the well known CLOTBUST study (<300mw/sq cm)for one hour, using two probes.

All will be treated as an outpatient and there is no form of infusion or interventional treatment.

The rapid magnetic stimulation is at about 50a/us, 15Hz, 1000 pulses with 10 sec pause for ten days along the skull vault. Informed consent will be obtained. 30 patients will be recruited and sham treatment would be just applying probe without power for transcranial and for magnetic stimulation coil will be angled away. Data will be compiled by a separate blinded investigator and so with the statistics. VP shunt failure patients, which is common, will be included. Barthel's daily living index and standard cognitive tests will be used to assess results.

Study Type

Observational

Enrollment (Anticipated)

30

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

  • Name: Devathasan Gobinathan, FRCP,MD
  • Phone Number: 65-67330311
  • Email: devathasan@msn.com

Study Contact Backup

  • Name: Weng Kiong Ow Yong, Bsc
  • Phone Number: 65-97970966
  • Email: gdeva@yahoo.com

Study Locations

  • Singapore
      • Singapore, Singapore, 228510
        • Recruiting
        • Devathasan Neurology Practice #11-16 MEMC
        • Principal Investigator:
          • Devathasan Gobinathan, FRCP MD
      • Singapore, Singapore, 228510
        • Recruiting
        • Devathasan Neurology Practice
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • cerebral ischemia with our without hydrocephalus and gait apraxia

Exclusion Criteria:

  • all other conditions which contribute to walking difficulty e.g. bad knees; or spondylosis; parkinson's or paralytic strokes

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Devathasan Neurology Practice Pte Ltd

Investigators

  • Study Chair: Weng Kiong Aw Yong, Bsc (QUT), Freelancer Computer Programmer and data control

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

  • Devathasan G, Dinesh D. Rapid magnetic stimulation with sonolysis for gait apraxia due to to normal pressure hyprocephalus and cerebral ischemia. International Congress Series xx (2007)xxx-xxx( in press)

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2002

Study Completion (Anticipated)

June 1, 2007

Study Registration Dates

First Submitted

June 28, 2007

First Submitted That Met QC Criteria

June 28, 2007

First Posted (Estimate)

July 2, 2007

Study Record Updates

Last Update Posted (Estimate)

July 2, 2007

Last Update Submitted That Met QC Criteria

June 28, 2007

Last Verified

June 1, 2007

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 02

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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