- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00509314
The Mechanism of Melanocyte Self-Assembly on Biomaterials and the Functional Analysis
July 29, 2007 updated by: National Taiwan University Hospital
The aim of this study is to survey melanocytes in the ability of self-assembly on biomaterials and functional analysis in vitro.
Also, this study may provide a better way for treatment of vitiligo after understanding the functional aspects of melanocytes.
Study Overview
Status
Unknown
Conditions
Intervention / Treatment
Detailed Description
Vitiligo is a chronic disease that causes loss of melanocyte and pigment of the skin.
Traditional treatments for vitiligo including topical corticosteroids and phototherapy lead to limited clinical effects.
Autologous melanocyte transplantation is another way to treat vitiligo.
However, the effect is largely affected by whether cultivated melanocytes are successfully uptaken by vitiliginous skin.
The aim of this study is to survey the self-assembly on biomaterials and functional analysis.
In the long run, this study may provide a better way for treatment of vitiligo.
Study Type
Observational
Enrollment (Anticipated)
400
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Taipei, Taiwan, 100
- Recruiting
- National Taiwan University Hospital
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Principal Investigator:
- Sung-Jan Lin, MD PhD
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 60 years (Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Patients receiving cosmetic removal of moles
Exclusion Criteria:
- No special exclusion criteria
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Lin SJ, Jee SH, Hsaio WC, Lee SJ, Young TH. Formation of melanocyte spheroids on the chitosan-coated surface. Biomaterials. 2005 Apr;26(12):1413-22. doi: 10.1016/j.biomaterials.2004.05.002.
- Lin SJ, Jee SH, Hsiao WC, Yu HS, Tsai TF, Chen JS, Hsu CJ, Young TH. Enhanced cell survival of melanocyte spheroids in serum starvation condition. Biomaterials. 2006 Mar;27(8):1462-9. doi: 10.1016/j.biomaterials.2005.08.031. Epub 2005 Sep 19.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
May 1, 2006
Study Completion (Anticipated)
December 1, 2016
Study Registration Dates
First Submitted
July 29, 2007
First Submitted That Met QC Criteria
July 29, 2007
First Posted (Estimate)
July 31, 2007
Study Record Updates
Last Update Posted (Estimate)
July 31, 2007
Last Update Submitted That Met QC Criteria
July 29, 2007
Last Verified
May 1, 2006
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 9561703036
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.