- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00533754
Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population
The aim of the study is to show a higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals.
Additionaly a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD.
Study Overview
Status
Conditions
Intervention / Treatment
Study Type
Phase
- Not Applicable
Contacts and Locations
Study Locations
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-
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Vienna, Austria, 1030
- Rudoulf foundation Clinic
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- man and women over 18 years old
- Filled out informed consentBereitschaft zur Teilnahme
- Diagnosis of non-exudative/ exudative age related macular dgeneneration
Exclusion Criteria:
- inherited retinal diseases
- other aquired retinal/ macular
- missing informed consent
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: Single
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
---|
higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals
|
Secondary Outcome Measures
Outcome Measure |
---|
a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD
|
Collaborators and Investigators
Sponsor
Investigators
- Study Chair: Susanne Binder, M.D., Rudoulf foundation Clinic
Study record dates
Study Major Dates
Study Start
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- EK 06-076-VK
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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