VEGF as a Prognostic Factor for White Matter Damage in Preterm Infants

We hypothesize that misexpression of vascular endothelial growth factor (VEGF) in the Cerebrospinal fluid of preterm infants can be used as a biomarker to predict the risk for developing white matter damage.

Study Overview

• Status: Withdrawn
• Conditions: Preterm Infants With White Matter Damage; Preterm Infants Developing Normally

• Study Type: Observational

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 5 months to 9 months (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

preterm infants.

Description

Inclusion Criteria:

• Preterm infants undergoing lumbar puncture.

Exclusion Criteria:

• Preterm with IVH or known infection or meningitis.

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
1
2

Collaborators and Investigators

• Sponsor: Hadassah Medical Organization
• Investigators: Principal Investigator: Talya Dor, MD, Hadassah Medical Organization

Study record dates

Study Major Dates

• Study Start: January 1, 2008
• Study Completion (Anticipated): January 1, 2009

Study Registration Dates

• First Submitted: November 25, 2007
• First Submitted That Met QC Criteria: November 26, 2007
• First Posted (Estimate): November 27, 2007

Study Record Updates

• Last Update Posted (Estimate): September 2, 2016
• Last Update Submitted That Met QC Criteria: September 1, 2016
• Last Verified: November 1, 2007

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pregnancy Complications; Obstetric Labor Complications; Obstetric Labor, Premature; Premature Birth
• Other Study ID Numbers: 606060-HMO-CTIL