A Study to Describe Pediatric Influenza Vaccine Coverage

An Observational Study to Describe Pediatric Influenza Vaccine Coverage Among Pediatricians in the United States

The purpose of this study is to describe flu vaccine coverage in children under 18 years of age and to examine correlations between in-office flu vaccine coverage and the use of various tactics to increase vaccine coverage.

Study Overview

• Status: Completed
• Conditions: Healthy
• Intervention / Treatment: Biological: Influenza vaccination

Detailed Description

To describe influenza vaccine coverage in children less than 18 years of age in practicing pediatricians' offices and family medicine physicians' offices and to examine correlations between in-office influenza vaccine coverage and the use of various tactics to increase vaccine coverage.

• Study Type: Observational
• Enrollment (Actual): 147494

Contacts and Locations

Study Locations

• United States
  • Alabama
    • Birmingham, Alabama, United States, 35242
      • Ark-La-Tex Pediatric Research
    • Daphne, Alabama, United States, 36526
      • Jordan Ridge Kids and Teens
    • Daphne, Alabama, United States, 36526
      • Pediatrics by the Bay
    • Montgomery, Alabama, United States, 36117
      • Montgomery Pediatric Associates, PA
    • Sheffield, Alabama, United States, 35660
      • Tennessee Valley Pediatric Associates
    • Wetumpka, Alabama, United States, 36092
      • Carlile Pediatrics
  • Alaska
    • Wasilla, Alaska, United States, 99654
      • Adventures in Pediatrics
  • Arizona
    • Chandler, Arizona, United States, 85224
      • Pendleton Pediatrics
    • Phoenix, Arizona, United States, 85003
      • Armadillo Pediatrics
    • Scottsdale, Arizona, United States, 85255
      • Grayhawk Pediatrics
    • Scottsdale, Arizona, United States, 85258
      • North Scottsdale Pediatrics Associates
    • Scottsdale, Arizona, United States, 85258
      • Papago Buttes Pediatric Center PC
    • Tucson, Arizona, United States, 85741
      • Cholla Pediatrics
  • Arkansas
    • Benton, Arkansas, United States, 72019
      • Central Arkansas Pediatric Clinic
    • Bentonville, Arkansas, United States, 72712
      • Children's Investigational Research Program
    • Bentonville, Arkansas, United States, 72172
      • Bentonville Pediatrics
    • N. Little Rock, Arkansas, United States, 72117
      • The Pediatric Clinic
    • Wasilla, Arkansas, United States, 99654
      • Adventures in Pediatrics
  • California
    • Bell Gardens, California, United States, 90201
      • Gardens Medical Center
    • Covina, California, United States, 91723
      • Pratima Patel, MD
    • Folsom, California, United States, 95630
      • Mission Care Pediatrics
    • Fresno, California, United States, 93726
      • Razia Sheikh
    • Huntington Park, California, United States, 90255
      • Del Rosario Medical Clinic, Inc.
    • Oceanside, California, United States, 92054
      • Ching Ti, M.D.
    • Poway, California, United States, 92064
      • Providence Pediatrics
    • San Francisco, California, United States, 94132
      • Stonestown Pediatrics
    • Santa Ana, California, United States, 92705
      • Eugene I Litwer
    • Van Nuys, California, United States, 91405
      • Louella Peckson, MD
  • Colorado
    • Durango, Colorado, United States, 81301
      • Pediatric Partners of the Southwest
    • Evergreen, Colorado, United States, 80439
      • Evergreen Pediatrics
    • Pueblo, Colorado, United States, 81003
      • Children's Clinic of Pueblo
  • Connecticut
    • Darien, Connecticut, United States, 06820
      • Darien Pediatric Associates
    • Norwich, Connecticut, United States, 06360
      • Norwich Pediatric Group PC
    • Prospect, Connecticut, United States, 06712
      • Prospect Family Practice
    • Westport, Connecticut, United States, 06880
      • Bay Street Pediatrics
  • Florida
    • Atlantis, Florida, United States, 33462
      • JFK Pediatrics
    • Bradenton, Florida, United States, 34207
      • Giangreco, Scarano & Taylor Pediatrics
    • Brandon, Florida, United States, 33511
      • Kids and More Pediatric Care
    • Coral Springs, Florida, United States, 33065
      • Sawgrass Pediatrics
    • Homestead, Florida, United States, 33030
      • Ramon Maldonado, MD
    • Merrit Island, Florida, United States, 32953
      • Atlantic Coast Pediatrics
    • Miami, Florida, United States, 33176
      • Guillermo S. Llosa, MD PA
    • New Port Richey, Florida, United States, 34655
      • The Pediatric Specialists Medical Group
    • Orange Park, Florida, United States, 32073
      • Orange Park Pediatrics
    • Plantation, Florida, United States, 33324
      • Childrens Medical Association
    • Saint Pete Beach, Florida, United States, 33709
      • St Pete Pediatrics
    • St. Petersburg, Florida, United States, 33705
      • Lynne Ellis
    • Wesley Chapel, Florida, United States, 33544
      • Wesley Chapel Internal Medicine & Pediatrics PA
  • Georgia
    • College Park, Georgia, United States, 30349
      • KidCare Pediatrics, LLC
    • Jesup, Georgia, United States, 31545
      • Jesup Pediatrics
    • Marietta, Georgia, United States, 30068
      • Pediatric and Adolescent Healthcare, PC
    • Ringgold, Georgia, United States, 30736
      • Sandy Plains Pediatrics
    • Snellville, Georgia, United States, 30078
      • Zaman Pediatric Center
  • Illinois
    • Darien, Illinois, United States, 60561
      • DuPage Pediatrics
    • Evergreen Park, Illinois, United States, 60805
      • Alzein Pediatrics
    • LaGrange, Illinois, United States, 60525
      • Mary E. Lewis MD. PC
    • Libertyville, Illinois, United States, 60048
      • Lake Shore Pediatrics
    • Muskegon, Illinois, United States, 49444
      • Port City Pediatrics
    • Vernon Hills, Illinois, United States, 60061
      • North Suburban Family Healthcare
  • Indiana
    • Fort Wayne, Indiana, United States, 46804
      • Pediatric Associates Inc
    • Indianapolis, Indiana, United States, 46256
      • Northpoint Pediatrics
    • Jeffersonville, Indiana, United States, 47130
      • Jeffersonville Pediatrics
    • Mishawaka, Indiana, United States, 46545
      • Del Pilar Medical & Urgent Care Center
    • Rushville, Indiana, United States, 46173
      • RMH Pediatrics
  • Iowa
    • Cedar Rapids, Iowa, United States, 52404
      • MercyCare Edgewood
    • Council Bluffs, Iowa, United States, 51503
      • Alegent Health Clinic
  • Kansas
    • Leavenworth, Kansas, United States, 66048
      • St. John's Pediatrics
  • Kentucky
    • Florence, Kentucky, United States, 41042
      • Paul J. Janson, MD
    • La Grange, Kentucky, United States, 40031
      • Oldham County Pediatrics
  • Louisiana
    • Baton Rouge, Louisiana, United States, 70806
      • Associates in Pediatrics
    • Bossier City, Louisiana, United States, 71111
      • Ark-La-Tex Pediatric Research
    • Lake Providence, Louisiana, United States, 71254
      • Family Practice Pediatric Clinic
    • Leesville, Louisiana, United States, 71446
      • Allstar Pediatrics (LEESVILLE, LA)
    • Slidell, Louisiana, United States, 70461
      • Pearl Acres Pediatrics
  • Michigan
    • Big Rapids, Michigan, United States, 49307
      • Mecosta Health Services
    • Deckerville, Michigan, United States, 48427
      • Deckerville Health Services
    • Muskegon, Michigan, United States, 49444
      • Port City Pediatrics
    • Royal Oak, Michigan, United States, 48067
      • Merrillwood Pediatrics
  • Minnesota
    • Vadnais Heights, Minnesota, United States, 55110
      • Northern Lights Pediatrics
  • Missouri
    • Bridgeton, Missouri, United States, 63044
      • Tots Thru Teens
    • Kansas City, Missouri, United States, 64155
      • Priority Care Pediatrics
    • Lee's Summit, Missouri, United States, 64086
      • Preferred Pediatrics
    • Mount Vernon, Missouri, United States, 65712
      • Country Corner Family Medical Center
  • Nebraska
    • Omaha, Nebraska, United States, 68130
      • Midwest Allergy and Asthma Clinic
  • Nevada
    • Henderson, Nevada, United States, 89015
      • Henderson Pediatrics
    • Henderson, Nevada, United States, 89052
      • Anthem Pediatrics
    • Las Vegas, Nevada, United States, 89128
      • Harold Naiman, MD
  • New Jersey
    • East Orange, New Jersey, United States, 07018
      • Mediterranean Pediatrics
    • Green Brook, New Jersey, United States, 08812
      • Ronald M. Frank, MD, PA
    • N. Brunswick, New Jersey, United States, 08902
      • Plaza Pediatrics
    • Phillipsburg, New Jersey, United States, 08865
      • New Beginnings Pediatrics
    • Vineland, New Jersey, United States, 08360
      • Pediatric Associates of New Jersey
  • New York
    • Clifton Park, New York, United States, 12065
      • Four Seasons Pediatrics
    • Delmar, New York, United States, 12054
      • Delmar Family Medicine
    • Delmar, New York, United States, 12054
      • Prime Care Physicians
    • Fairport, New York, United States, 14450
      • Perinton Pediatrics
    • Floral Park, New York, United States, 11001
      • Park Pediatrics
    • Garden City, New York, United States, 11530
      • Garden City Pediatric
    • Levittown, New York, United States, 11564
      • ProKids, LLP
    • New City, New York, United States, 10956
      • Clarkstown Pediatrics
    • North Syracuse, New York, United States, 13212
      • North Court Pediatrics
    • Orchard Park, New York, United States, 14127
      • Orchard Park Pediatrics
    • Pomona, New York, United States, 10970
      • Pomona Pediatrics
    • Rochester, New York, United States, 14618
      • Edward Lewis, M.D., P.C.
  • North Carolina
    • Asheboro, North Carolina, United States, 27203
      • Asheboro Research Associates
    • Asheville, North Carolina, United States, 28803
      • Asheville Pediatric Association
    • Beone, North Carolina, United States, 28607
      • Blue Ridge Pediatric and Adolescent Medicine
    • Burlington, North Carolina, United States, 27215
      • Cornerstone Medical Center
    • Cary, North Carolina, United States, 27518
      • Cary Medical Research
    • Clyde, North Carolina, United States, 28721
      • Haywood Pediatrics
    • Greensboro, North Carolina, United States, 27405-6930
      • Lucas Pediatrics
    • Greensboro, North Carolina, United States, 27410
      • Briargate Medical Associates
    • Greensboro, North Carolina, United States, 27410
      • Northwest Pediatrics, Inc.
    • Henderson, North Carolina, United States, 28739
      • Rainbow Pediatrics
    • Hendersonville, North Carolina, United States, 28792
      • Blue Ridge Community Health Services
    • Morganton, North Carolina, United States, 28655
      • Mountain View Pediatrics, P.A.
    • Rockingham, North Carolina, United States, 28379
      • Masoud Ahdieh MD
    • Whiteville, North Carolina, United States, 28472
      • Columbus Pediatrics and Adolescent Care
    • Winston-Salem, North Carolina, United States, 27103
      • Piedmont Medical Research
  • Ohio
    • Canfield, Ohio, United States, 44406
      • Kids First Pediatrics
    • Canton, Ohio, United States, 44704
      • Shipley Child Health Clinic
    • Canton, Ohio, United States, 44708
      • Stark Pediatrics Inc.
    • Cincinnati, Ohio, United States, 45245
      • Pediatric Associates of Mt. Carmel
    • Cincinnati, Ohio, United States, 45230
      • Anderson Hills Pediatrics, Inc.
    • Fairfield, Ohio, United States, 45014
      • Pediatric Associates of Fairfield
    • Mason, Ohio, United States, 45040
      • Landen Lake Pediatrics
    • Mentor, Ohio, United States, 44060
      • Euclid Pediatrics
    • Milford, Ohio, United States, 45150
      • ESD Pediatric Group
    • Toledo, Ohio, United States, 43617
      • Crown Point Pediatrics
    • Youngstown, Ohio, United States, 44505
      • Pediatric Associates of Youngstown
  • Oregon
    • Gresham, Oregon, United States, 97030
      • Pediatric Associates of Gresham
    • McMinnville, Oregon, United States, 97218
      • PMC
    • Medford, Oregon, United States, 97504
      • Johnson Pediatrics
    • Oregon City, Oregon, United States, 97045
      • Jo Anne Nielsen, MD
  • Pennsylvania
    • Bellevue, Pennsylvania, United States, 15202
      • Bellevue Pediatrics
    • Collegeville, Pennsylvania, United States, 19426
      • PMA Medical Specialists, LLC
    • Johnstown, Pennsylvania, United States, 15905
      • Franklin Street Pediatrics
    • Lancaster, Pennsylvania, United States, 17601
      • Eden Park Pediatric
    • Lock Haven, Pennsylvania, United States, 17745
      • Praful Bhatt, MD
    • McMurray, Pennsylvania, United States, 15317
      • McMurray Pediatric & Adolescent Medicine
    • Mckees Rock, Pennsylvania, United States, 15136
      • Pediatrics South- Robinson
    • Philadelphia, Pennsylvania, United States, 19114
      • Red Lion Pediatrics
    • Philadelphia, Pennsylvania, United States, 19119
      • Mt. Airy Pediatrics, LLP
    • Quakertown, Pennsylvania, United States, 18951
      • Cevallos & Moise Pediatrics
    • Sellersville, Pennsylvania, United States, 18960
      • Pennridge Pediatric Associates
    • Williamsport, Pennsylvania, United States, 17701
      • Susquehanna Int. Med. Pediatrics
  • Rhode Island
    • Providence, Rhode Island, United States, 02906
      • Lake Area Pediatrics
  • South Carolina
    • Charleston, South Carolina, United States, 29414
      • Coastal Pediatric Associates
    • Mt. Pleasant, South Carolina, United States, 29464
      • Palmetto Medical Research, LLC
  • Tennessee
    • Crossville, Tennessee, United States, 38555
      • Plateau Pediatrics
    • Crossville, Tennessee, United States, 38555
      • Siskiyou Pediatric Clinic, LLP
    • Franklin, Tennessee, United States, 37067
      • Cool Springs Pediatrics
    • Lebanon, Tennessee, United States, 37087
      • Cumberland Pediatric Associates
    • Maryville, Tennessee, United States, 37803
      • Cedar Creek Pediatrics & Adolescent Medicine
    • Memphis, Tennessee, United States, 38104
      • Sheffield Pediatrics
    • Soddy Daisy, Tennessee, United States, 37379
      • Soddy Daisy Pediatrics
    • Tullahoma, Tennessee, United States, 37388
      • Pediatric Clinical Trials, LLC
  • Texas
    • Brownsville, Texas, United States, 78526
      • Jorge A Patino MD PA
    • Coppell, Texas, United States, 75019
      • Coppell Pediatrics
    • Dallas, Texas, United States, 75208
      • Sarah L. Helfand, M.D.
    • Dallas, Texas, United States, 75230
      • Healthy Texan Pediatrics and Family Medicine
    • Frisco, Texas, United States, 75034
      • Iresh Kumar MD
    • Houston, Texas, United States, 77087
      • Pediatric Associates
    • Houston, Texas, United States, 77054
      • Texas Childrens Pediatric Associates
    • Houston, Texas, United States, 77205
      • VIP Pediatrics
    • Lubbock, Texas, United States, 79424
      • Pediatric Associates of Lubbock
    • Montgomery, Texas, United States, 77356
      • Pediatric Care Associates, LLC
    • Mount Pleasant, Texas, United States, 75455
      • The Pediatric Clinic, P.A.
    • Plano, Texas, United States, 75075
      • Pediatric Associates of North Texas
    • San Antonio, Texas, United States, 78229
      • Southwest Children's Research Associates, P.A.
    • San Antonio, Texas, United States, 78212
      • ChildCare Associates
    • Tejas, Texas, United States, 78258
      • Tejas Pediatrics
    • Webster, Texas, United States, 77598
      • A Brighter Tomorrow Pediatrics
    • Webster, Texas, United States, 77598
      • Sunshine Kids Medical Associates
  • Utah
    • Odgen, Utah, United States, 84404
      • Jean Brown Research-Odgen Clinic
    • Orem, Utah, United States, 84057
      • Utah Valley Pediatrics
    • West Jordan, Utah, United States, 84088
      • Valle Verde Pediatrics
  • Virginia
    • Alexandria, Virginia, United States, 22302
      • Van Dorn Pediatrics
    • King George, Virginia, United States, 22485
      • King George Pediatrics
    • Midlothian, Virginia, United States, 23112
      • Woodlake Village Pediatrics
    • Richmond, Virginia, United States, 23233
      • Richmond Pediatric Associates
    • Stafford, Virginia, United States, 22554-1545
      • Stafford Pediatrics, P.C.
  • Washington
    • Redmond, Washington, United States, 98052
      • Redmond Pediatrics
    • Spokane, Washington, United States, 99208
      • Elizabeth A. Tomeo, MD
  • Wisconsin
    • Beaver Dam, Wisconsin, United States, 53916
      • Community Pediatrics
    • Muskego, Wisconsin, United States, 53150
      • Pro Health Care Medical Associates
    • Oconomowoc, Wisconsin, United States, 53066
      • Lake Country Pediatrics

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 6 months and older (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Physician offices that were selected to participate in the study

Description

Sites selected to participate were required to be able to accurately identify the number of patients under their care by age group and provide influenza vaccine at their location.

Study Plan

How is the study designed?

Number of groups / cohorts

4

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Participants 6 to 23 months; Pediatric influenza vaccine coverage within practicing pediatricians' offices for participants 6 to 23 months of age	Biological: Influenza vaccination; This non-interventional study prospectively captured vaccine coverage and practices of participating physician offices through use of surveys during the influenza vaccination season.
Participants 24 to 59 months; Pediatric influenza vaccine coverage within practicing pediatricians' offices for participants 24 to 59 months of age	Biological: Influenza vaccination; This non-interventional study prospectively captured vaccine coverage and practices of participating physician offices through use of surveys during the influenza vaccination season.
Participants 5 to 8 years; Pediatric influenza vaccine coverage within practicing pediatricians' offices for participants 5 to 8 years of age	Biological: Influenza vaccination; This non-interventional study prospectively captured vaccine coverage and practices of participating physician offices through use of surveys during the influenza vaccination season.
Participants 9 to 17 years; Pediatric influenza vaccine coverage within practicing pediatricians' offices for participants 9 to 17 years of age	Biological: Influenza vaccination; This non-interventional study prospectively captured vaccine coverage and practices of participating physician offices through use of surveys during the influenza vaccination season.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Influenza Vaccine Coverage in Participants <18 Years of Age by Age Group in Pediatric Practices	Vaccine coverage was calculated from the number of participants vaccinated in each group, divided by the total number of participants under the practice's care in that specific age group.	Seasonal: 2007-2011

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Compliance With the Recommended Two-dose Regimen in Vaccinated Participants	Compliance was calculated from the total number of participants receiving 2 doses divided by the total number of participants identified as requiring a second dose.	Seasonal: 2007-2011
Correlation of Office Vaccination-related Attitudes and Activities With Actual Vaccine Coverage	Correlation of office attitudes related to influenza vaccination and actual vaccine coverage was explored. Sites were asked to indicate level of agreement with the following recommendations: vaccinating children with high-risk medical conditions, patients 6 months to 5 years of age should be vaccinated against influenza each year, patients 5 to 18 years of age without high-risk medical conditions should be vaccinated against influenza each year, and previously unvaccinated patients less than 9 years of age receive 2 doses of vaccine.	Seasonal: 2007-2011

Collaborators and Investigators

• Sponsor: MedImmune LLC
• Investigators: Study Director: Chris Ambrose, M.D., MedImmune LLC

Publications and helpful links

General Publications

• Toback SL, Carr W, Hackell J, Bhatt P, Ryan A, Ambrose CS. Influenza vaccination of parents and guardians by US pediatricians. Hum Vaccin. 2011 Apr;7(4):436-40. doi: 10.4161/hv.7.4.14171. Epub 2011 Apr 1.
• Bhatt P, Block SL, Toback SL, Ambrose CS. Timing of the availability and administration of influenza vaccine through the vaccines for children program. Pediatr Infect Dis J. 2011 Feb;30(2):100-6. doi: 10.1097/INF.0b013e3181efff54.
• Bhatt P, Block SL, Toback SL, Ambrose CS. A prospective observational study of US in-office pediatric influenza vaccination during the 2007 to 2009 influenza seasons: use and factors associated with increased vaccination rates. Clin Pediatr (Phila). 2010 Oct;49(10):954-63. doi: 10.1177/0009922810370868. Epub 2010 Jun 3.

Study record dates

Study Major Dates

• Study Start: August 1, 2007
• Primary Completion (Actual): March 1, 2011
• Study Completion (Actual): June 1, 2011

Study Registration Dates

• First Submitted: March 4, 2008
• First Submitted That Met QC Criteria: March 19, 2008
• First Posted (Estimate): March 20, 2008

Study Record Updates

• Last Update Posted (Estimate): September 15, 2014
• Last Update Submitted That Met QC Criteria: September 12, 2014
• Last Verified: September 1, 2014

More Information

Terms related to this study

• Other Study ID Numbers: MI-MA156