Long-term Cardiovascular Risk in Cured Cushing's Patients

August 31, 2020 updated by: Karen Klahr Miller, MD, Massachusetts General Hospital

Role of Adipokines in Long-term Cardiovascular Risk in Cured Cushing's Patients

The purpose of this study is to determine whether subjects who have been affected by Cushing's disease in the past maintain some different characteristics compared with subjects who have never been diagnosed with the disease.

Study Overview

Status

Terminated

Conditions

Cushing's Disease

Study Type

Observational

Enrollment (Actual)

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

United States
- Massachusetts
  - Boston, Massachusetts, United States, 02114
    - Neuroendocrine Clinical Center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

35 years to 55 years (Adult)

Accepts Healthy Volunteers

Genders Eligible for Study

Female

Sampling Method

Probability Sample

Study Population

Cured Cushing's disease

Description

Inclusion Criteria:

patients who have been cured of Cushing's disease at least 5 years ago.

Exclusion Criteria:

patients who have been cured of Cushing's disease more than 15 years ago.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort
cured Cushing's disease

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
adipokine measurements Time Frame: baseline	baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Massachusetts General Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 8, 2008

Primary Completion (Actual)

March 30, 2010

Study Completion (Actual)

March 30, 2010

Study Registration Dates

First Submitted

April 13, 2009

First Submitted That Met QC Criteria