- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01128010
Role of CCL2 in Alcoholic Liver Diseases
Study Overview
Status
Conditions
Study Type
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Consecutive patients undergoing transjugular liver biopsy for alcoholic liver disease will be include in the study to measure plasma levels and hepatic expression of CCL2. We determine also the rs1024611 polymorphism of these patients. All these parameters are correlated to severity of the disease.
The frequency of the presence of this polymorphism was also compared to a population of healthy subjects.
Description
ALD patients
Inclusion Criteria:
- Excess alcohol intake
- Abnormality of liver biopsy compatible with alcoholic aetiology
- Caucasian ethnicity
Exclusion Criteria:
- Presence of any other chronic liver disease
- co-infection with HIV Controls Inclusion criteria
- Caucasian ethnicity
- presence of a disease
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
---|
alcoholic liver disease
alcoholic liver disease patients undergoing a transjugular liver biopsy in our institution
|
controls
Healthy controls patients recruited from the Occupational Medicine Department during a routine physical examination
|
Collaborators and Investigators
Sponsor
Study record dates
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- DD-CCL2
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