Tumor Landscape Pathological Diagnosis by Large Tissue Sections

The aim of this study is to establish large tissue sections for 10 kinds of tumors. in order to observe the tumor landscape on microscope. The tumors including esophageal carcinoma,gastric carcinoma,hepatocellular carcinoma etc.200 cases of each tumor will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .

Study Overview

• Status: Unknown
• Conditions: Pathology
• Intervention / Treatment: Diagnostic test: landscape sample method

• Study Type: Observational
• Enrollment (Anticipated): 2000

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 15 years and older (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

ZhongShan Hospital，FuDan University

Description

Inclusion Criteria:

1. Older than 15-year-old
2. Did not receive preoperative preoperative chemotherapy or radiotherapy

Exclusion Criteria:

patients undergoing preoperative chemotherapy or radiotherapy

Study Plan

How is the study designed?

Number of groups / cohorts

20

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
prostate ,traditional sample method; Samples from 100 patients with prostate carcinoma were obtained by traditional sampling method
prostate ,landscape sample method; Samples from 100 patients with prostate carcinoma were obtained by landscape sampling method to testify the clinical value and significance of tumor landscape pathological diagnosis .	Diagnostic test: landscape sample method; 200 cases of different tumor tissues will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .; Other Names: traditional sample method
liver, traditional sample method; Samples from 100 patients with liver cancer were obtained by traditional sampling method.
liver,landscape sample method; Samples from 100 patients with liver cancer were obtained by landscape sampling method to testify the clinical value and significance of tumor landscape pathological diagnosis .	Diagnostic test: landscape sample method; 200 cases of different tumor tissues will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .; Other Names: traditional sample method
esophageal ,traditional sample method; Samples from 100 patients with esophageal carcinoma were obtained by traditional sampling method.
esophageal ,landscape sample method; Samples from 100 patients with esophageal carcinoma were obtained by landscape sampling method to testify the clinical value and significance of tumor landscape pathological diagnosis .	Diagnostic test: landscape sample method; 200 cases of different tumor tissues will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .; Other Names: traditional sample method
GIST,traditional sample method; Samples from 100 patients with gastrointestinal stromal tumor were obtained by traditional sampling method.
GIST,landscape sample method; Samples from 100 patients with gastrointestinal stromal tumor were obtained by landscape sampling method to testify the clinical value and significance of tumor landscape pathological diagnosis .	Diagnostic test: landscape sample method; 200 cases of different tumor tissues will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .; Other Names: traditional sample method
colorectal ,traditional sample method; Samples from 100 patients with colorectal carcinoma were obtained by traditional sampling method.
colorectal ,landscape sample method; Samples from 100 patients with colorectal carcinoma were obtained by landscape sampling method to testify the clinical value and significance of tumor landscape pathological diagnosis .	Diagnostic test: landscape sample method; 200 cases of different tumor tissues will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .; Other Names: traditional sample method
pancreatic ,traditional sample method; Samples from 100 patients with pancreatic carcinoma were obtained by traditional sampling method.
pancreatic,landscape sample method; Samples from 100 patients with pancreatic carcinoma were obtained by landscape sampling method to testify the clinical value and significance of tumor landscape pathological diagnosis .	Diagnostic test: landscape sample method; 200 cases of different tumor tissues will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .; Other Names: traditional sample method
lung cancer,traditional sample method; Samples from 100 patients with lung cancer were obtained by traditional sampling method.
lung cancer,landscape sample method; Samples from 100 patients with lung cancer were obtained by landscape sampling method to testify the clinical value and significance of tumor landscape pathological diagnosis .	Diagnostic test: landscape sample method; 200 cases of different tumor tissues will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .; Other Names: traditional sample method
Renal ,traditional sample method; Samples from 100 patients with renal carcinoma were obtained by traditional sampling method.
Renal carcinoma,landscape sample method; Samples from 100 patients with renal carcinoma were obtained by landscape sampling method to testify the clinical value and significance of tumor landscape pathological diagnosis .	Diagnostic test: landscape sample method; 200 cases of different tumor tissues will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .; Other Names: traditional sample method
Breast cancer,traditional sample method; Samples from 100 patients with breast cancer were obtained by traditional sampling method.
Breast cancer,landscape sample method; Samples from 100 patients with breast cancer were obtained by landscape sampling method to testify the clinical value and significance of tumor landscape pathological diagnosis .	Diagnostic test: landscape sample method; 200 cases of different tumor tissues will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .; Other Names: traditional sample method
cervical ,traditional sample method; Samples from 100 patients with cervical carcinoma were obtained by traditional sampling method.
cervical ,landscape sample method; Samples from 100 patients with cervical carcinoma were obtained by landscape sampling method to testify the clinical value and significance of tumor landscape pathological diagnosis .	Diagnostic test: landscape sample method; 200 cases of different tumor tissues will be compared by traditional sample method and landscape sample method to testify the clinical value and significance of tumor landscape pathological diagnosis .; Other Names: traditional sample method

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Prostate，traditional and landscape sample method	200 cases of prostate carcinoma sampled by traditional method and landscape method will be compared for precise and comprehensive pathological analysis.	1st January, 2018 ~30th June, 2018
liver,traditional and landscape sample method	200 cases of liver cancer sampled by traditional method and landscape method will be compared for precise and comprehensive pathological analysis.	1st January, 2018 ~30th June, 2018
esophageal,traditional and landscape sample method	200 cases of esophageal carcinoma sampled by traditional method and landscape method will be compared for precise and comprehensive pathological analysis.	1st January, 2018 ~30th June, 2018
GIST,traditional and landscape sample method	200 cases of gastrointestinal stromal tumor (GIST)sampled by traditional method and landscape method will be compared for precise and comprehensive pathological analysis.	1st July, 2018 ~31st December, 2018
colorectal,traditional and landscape sample method	200 cases of colorectal carcinoma sampled by traditional method and landscape method will be compared for precise and comprehensive pathological analysis.	1st July, 2018 ~31st December, 2018
pancreatic,traditional and landscape sample method	200 cases of pancreatic carcinoma sampled by traditional method and landscape method will be compared for precise and comprehensive pathological analysis.	1st July, 2018 ~31st December, 2018
lung, traditional and landscape sample method	200 cases of lung cancer sampled by traditional method and landscape method will be compared for precise and comprehensive pathological analysis.	1st July, 2018 ~31st December, 2018
renal,traditional and landscape sample method	200 cases of renal carcinoma sampled by traditional method and landscape method will be compared for precise and comprehensive pathological analysis.	1st July, 2018 ~31st December, 2018
breast,traditional and landscape sample method	200 cases of breast cancer sampled by traditional method and landscape method will be compared for precise and comprehensive pathological analysis.	1st July, 2018 ~31st December, 2018
cervical,traditional and landscape sample method	200 cases of cervical carcinoma sampled by traditional method and landscape method will be compared for precise and comprehensive pathological analysis.	1st July, 2018 ~31st December, 2018

Collaborators and Investigators

• Sponsor: Shanghai Zhongshan Hospital

Study record dates

Study Major Dates

• Study Start (Anticipated): January 1, 2018
• Primary Completion (Anticipated): December 31, 2019
• Study Completion (Anticipated): June 30, 2021

Study Registration Dates

• First Submitted: November 9, 2017
• First Submitted That Met QC Criteria: December 12, 2017
• First Posted (Actual): December 19, 2017

Study Record Updates

• Last Update Posted (Actual): December 19, 2017
• Last Update Submitted That Met QC Criteria: December 12, 2017
• Last Verified: December 1, 2017

More Information

Terms related to this study

• Keywords: Tumor ,landscape ,pathological diagnosis
• Additional Relevant MeSH Terms: Pathologic Processes; Disease
• Other Study ID Numbers: B2017-113R

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No