Pan Tumor Rollover Study

June 2, 2026 updated by: Bristol-Myers Squibb

Pan-Tumor Study for Long-term Treatment of Cancer Patients Who Have Participated in BMS Sponsored Trials Investigating Nivolumab and Other Cancer Therapies

Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

1500

Phase

  • Phase 2

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

  • Name: First line of the email MUST contain NCT # and Site #.

Study Contact Backup

  • Name: BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
  • Phone Number: 855-907-3286
  • Email: Clinical.Trials@bms.com

Study Locations

  • Argentina
      • Buenos Aires, Argentina, C1199 ABH
        • Withdrawn
        • Local Institution - 0201
      • Buenos Aires, Argentina, C1426ANZ
        • Recruiting
        • Instituto Fleming
        • Contact:
          • Matias Chacon, Site 0030
          • Phone Number: +541138850425
      • CABA, Argentina, C1426ANZ
        • Withdrawn
        • Local Institution
      • Córdoba, Argentina, X 5002HWE
        • Recruiting
        • Fundacion Richardet Longo - IONC
        • Contact:
          • Martin Richardet, Site 0349
          • Phone Number: 5493516165267
      • Córdoba, Argentina, X5004FHP
        • Withdrawn
        • Local Institution - 0170
    • Buenos Aires
      • Berazategui, Buenos Aires, Argentina, 1880
        • Completed
        • Local Institution - 0199
    • Córdoba Province
      • Río Cuarto, Córdoba Province, Argentina, 5800
        • Recruiting
        • Instituto Médico Río Cuarto
        • Contact:
          • Alejo Lingua, Site 0415
          • Phone Number: 54351153819050
    • Río Negro Province
      • Viedma, Río Negro Province, Argentina, 8500
        • Recruiting
        • Centro de Investigaciones Clinicas. Clinica Viedma S.A.
        • Contact:
          • Ruben Kowalyszyn, Site 0405
          • Phone Number: 5492920601693
    • Santa Fe Province
      • Rosario, Santa Fe Province, Argentina, 2000
        • Recruiting
        • Sanatorio Parque
        • Contact:
          • Gaston Lucas Martinengo, Site 0407
    • Tucumán Province
      • San Miguel de Tucumán, Tucumán Province, Argentina, 4000
        • Recruiting
        • CAIPO Centro para la Atencion Integral del Paciente Oncologico
        • Contact:
          • Felipe Salvador Palazzo, Site 0376
          • Phone Number: 543814018300
      • San Miguel de Tucumán, Tucumán Province, Argentina, 4000
        • Completed
        • Local Institution - 0191
  • Australia
    • New South Wales
      • Coffs Harbour, New South Wales, Australia, 2450
        • Completed
        • Local Institution - 0045
      • North Sydney, New South Wales, Australia, 2060
        • Recruiting
        • Melanoma Institute Australia
        • Contact:
          • Georgina Long, Site 0062
          • Phone Number: 61299117336
      • Sydney, New South Wales, Australia, 2050
        • Completed
        • Local Institution - 0009
      • Waratah, New South Wales, Australia, 2298
        • Completed
        • Local Institution - 0193
      • Westmead, New South Wales, Australia, 2145
        • Completed
        • Local Institution - 0208
    • Queensland
      • Greenslopes, Queensland, Australia, 4120
        • Recruiting
        • Gallipoli Medical Foundation
        • Contact:
          • Victoria Atkinson, Site 0021
          • Phone Number: 0448632604
      • Greenslopes, Queensland, Australia, 4120
        • Withdrawn
        • Local Institution - 0372
      • South Brisbane, Queensland, Australia, 4101
        • Withdrawn
        • Local Institution
      • Southport, Queensland, Australia, 4215
        • Recruiting
        • Tasman Oncology Research Ltd
        • Contact:
          • Andrew Hill, Site 0347
          • Phone Number: +61756132480
    • South Australia
      • Adelaide, South Australia, Australia, 5000
        • Withdrawn
        • Local Institution
      • Elizabeth Vale, South Australia, Australia, 05112
        • Completed
        • Local Institution - 0196
    • Victoria
      • Ballarat, Victoria, Australia, 3350
        • Recruiting
        • BRICC - Ballarat Health Services
        • Contact:
          • Wasek Faisal, Site 0411
      • Fitzroy, Victoria, Australia, 3065
        • Completed
        • Local Institution - 0365
      • Malvern, Victoria, Australia, 3144
        • Recruiting
        • Cabrini Hospital Malvern
        • Contact:
          • Benjamin Brady, Site 0005
          • Phone Number: 0395086161
    • Western Australia
      • Murdoch, Western Australia, Australia, 6150
        • Withdrawn
        • Local Institution - 0174
  • Austria
      • Vienna, Austria, 1090
        • Completed
        • Local Institution - 0104
      • Vienna, Austria, 1090
        • Recruiting
        • Allgemeines Krankenhaus Wien
        • Contact:
          • Matthias Pinter, Site 0321
          • Phone Number: 4314040047440
      • Wels, Austria, 4600
        • Completed
        • Local Institution - 0145
    • Styria
      • Graz, Styria, Austria, 8036
        • Completed
        • Local Institution - 0254
    • Upper Austria
      • Linz, Upper Austria, Austria, 4020
        • Recruiting
        • Ordensklinikum Linz GmbH Elisabethinen
        • Contact:
          • Clemens Mayr, Site 0149
          • Phone Number: 4373276764600
  • Belgium
      • Brussels, Belgium, 1000
        • Withdrawn
        • Local Institution - 0329
      • Ghent, Belgium, 9000
        • Completed
        • Local Institution - 0232
      • Jette, Belgium, 1090
        • Completed
        • Local Institution - 0139
      • Liège, Belgium, 4000
        • Withdrawn
        • Local Institution - 0261
      • Sint-Niklaas, Belgium, 9100
        • Withdrawn
        • Local Institution - 0293
      • Yvoir, Belgium, 5530
        • Completed
        • Local Institution - 0157
  • Brazil
      • Rio de Janeiro, Brazil, 20220-280
        • Completed
        • Local Institution - 0266
      • Rio de Janeiro, Brazil, 22775-001
        • Completed
        • Local Institution - 0258
      • São Paulo, Brazil, 01308-060
        • Withdrawn
        • Local Institution - 0340
    • Minas Gerais
      • Belo Horizonte, Minas Gerais, Brazil, 30130090
        • Completed
        • Local Institution - 0260
    • Rio Grande do Sul
      • Ijuí, Rio Grande do Sul, Brazil, 98700-000
        • Recruiting
        • ONCOSITE - Centro de Pesquisa Clinica em Oncologia
        • Contact:
          • Fabio Franke, Site 0155
          • Phone Number: +5555991592101
      • Passo Fundo, Rio Grande do Sul, Brazil, 99010-080
        • Withdrawn
        • Local Institution - 0379
      • Porto Alegre, Rio Grande do Sul, Brazil, 90610-000
        • Recruiting
        • Hospital Sao Lucas da PUCRS
        • Contact:
          • Carlos Barrios, Site 0331
          • Phone Number: +555133203039
      • Porto Alegre, Rio Grande do Sul, Brazil, 90050-170
        • Recruiting
        • Irmandade da Santa Casa de Misericórdia de Porto Alegre
        • Contact:
          • Rodrigo Pereira, Site 0113
          • Phone Number: 555133598619
      • Porto Alegre, Rio Grande do Sul, Brazil, 90035-903
        • Not yet recruiting
        • Local Institution - 0093
        • Contact:
          • Site 0093
      • Porto Alegre, Rio Grande do Sul, Brazil, 91350-250
        • Withdrawn
        • Local Institution - 0399
    • São Paulo
      • Barretos, São Paulo, Brazil, 14784-400
        • Completed
        • Local Institution - 0264
      • São José do Rio Preto, São Paulo, Brazil, 15090-000
        • Completed
        • Local Institution - 0262
      • São Paulo, São Paulo, Brazil, 01246-000
        • Recruiting
        • ICESP - Instituto do Cancer do Estado de Soo Paulo
        • Contact:
          • Olavo Feher, Site 0302
          • Phone Number: 551138932684
      • São Paulo, São Paulo, Brazil, 01308-050
        • Withdrawn
        • Local Institution - 0263
      • São Paulo, São Paulo, Brazil, 01327-001
        • Recruiting
        • Hospital Alemao Oswaldo Cruz
        • Contact:
          • Ariel Kann, Site 0355
          • Phone Number: +551135490665
  • Canada
    • Alberta
      • Edmonton, Alberta, Canada, T6G 1Z2
        • Recruiting
        • Cross Cancer Institute
        • Contact:
          • Quincy Chu, Site 0111
          • Phone Number: 7804328248
    • British Columbia
      • Vancouver, British Columbia, Canada, V5Z 1L3
        • Withdrawn
        • Local Institution
    • Nova Scotia
      • Halifax, Nova Scotia, Canada, B3H1V7
        • Withdrawn
        • Local Institution
    • Ontario
      • Oshawa, Ontario, Canada, L1G 2B9
        • Completed
        • Local Institution - 0168
      • Toronto, Ontario, Canada, M5G 2M9
        • Recruiting
        • Princess Margaret Cancer Centre
        • Contact:
          • Marcus Butler, Site 0280
          • Phone Number: 4169464628
    • Quebec
      • Montreal, Quebec, Canada, H4A 3J1
        • Withdrawn
        • Local Institution - 0040
      • Montreal, Quebec, Canada, H4J 1C5
        • Withdrawn
        • Local Institution - 0308
  • Chile
      • Viña del Mar, Chile, 2540364
        • Withdrawn
        • Local Institution - 0079
    • Araucania
      • Temuco, Araucania, Chile, 4780000
        • Completed
        • Local Institution - 0363
    • Santiago Metropolitan
      • Providencia, Santiago Metropolitan, Chile, 7500713
        • Recruiting
        • Orlandi Oncología
        • Contact:
          • Francisco Orlandi Jorquera, Site 0398
          • Phone Number: 5656224339699
      • Santiago, Santiago Metropolitan, Chile
        • Recruiting
        • Bradford Hill Centro de Investigacion Clinica
        • Contact:
          • Mauricio Burotto, Site 0101
      • Santiago, Santiago Metropolitan, Chile, 7500921
        • Recruiting
        • Fundación Arturo López Pérez
        • Contact:
          • Mauricio Mahave, Site 0019
          • Phone Number: 5624205100
      • Santiago, Santiago Metropolitan, Chile, 7500921
        • Withdrawn
        • Local Institution
  • China
      • Hangzhou, China, 310003
        • Completed
        • Local Institution - 0306
      • Nanjing, China, 210009
        • Recruiting
        • Jiangsu Cancer Hospital
        • Contact:
          • Qing Zou, Site 0390
          • Phone Number: 13905173337
    • Anhui
      • Hefei, Anhui, China, 230031
        • Withdrawn
        • Local Institution - 0169
    • Beijing Municipality
      • Beijing, Beijing Municipality, China, 100853
        • Withdrawn
        • Local Institution - 0198
    • Guangdong
      • Guangzhou, Guangdong, China, 510080
        • Withdrawn
        • Local Institution
      • Guangzhou, Guangdong, China, 510515
        • Recruiting
        • Nanfang Hospital; Southern Medical University
        • Contact:
          • Ya-Bing Guo, Site 0383
          • Phone Number: 862061641945
    • Heilongjiang
      • Harbin, Heilongjiang, China, 150040
        • Withdrawn
        • Local Institution - 0245
      • Harbin, Heilongjiang, China, 150081
        • Recruiting
        • Harbin Medical University - Cancer Hospital
        • Contact:
          • Yuxian Bai, Site 0317
          • Phone Number: 8613945095085
      • Harbin, Heilongjiang, China, 150081
        • Completed
        • Local Institution - 0160
    • Hunan
      • Changsha, Hunan, China, 410008
        • Recruiting
        • Xiangya Hospital Central South University
        • Contact:
          • Min Li, Site 0309
          • Phone Number: 8613787103054
      • Changsha, Hunan, China, 410000
        • Withdrawn
        • Local Institution - 0172
      • Changsha, Hunan, China, 410011
        • Recruiting
        • Hunan Cancer Hospital
        • Contact:
          • Shanzhi Gu, Site 0316
          • Phone Number: +73188651669
    • Jiangsu
      • Nanjing, Jiangsu, China, 210009
        • Withdrawn
        • Local Institution - 0348
    • Jilin
      • Changchun, Jilin, China, 130103
        • Recruiting
        • Jilin Cancer Hospital
        • Contact:
          • Ying Liu, Site 0194
      • Changchun, Jilin, China, 130061
        • Recruiting
        • Jilin University (JLU) - First Affiliated Hospital - Cancer Center
        • Contact:
          • Wei Li, Site 0307
          • Phone Number: 8613756661267
    • Shaanxi
      • Xi'an, Shaanxi, China, 710038
        • Recruiting
        • Tangdu Hospital of Fourth Military Medical University
        • Contact:
          • Haichuan Su, Site 0318
    • Shan3XI
      • Xi'an, Shan3XI, China, 710700
        • Recruiting
        • Xian International Medical Center Hospital
        • Contact:
          • Guohong Han, Site 0395
          • Phone Number: 86+8613991969930
    • Shanghai Municipality
      • Shanghai, Shanghai Municipality, China, 200032
        • Recruiting
        • Fudan University - Shanghai Cancer Center FUSCC
        • Contact:
          • Xianghua Wu, Site 0305
          • Phone Number: 8613482888167
      • Shanghai, Shanghai Municipality, China, 200032
        • Withdrawn
        • Local Institution - 0278
      • Shanghai, Shanghai Municipality, China, 200032
        • Withdrawn
        • Local Institution - 0325
      • Shanghai, Shanghai Municipality, China, 200433
        • Completed
        • Local Institution - 0188
      • Shanghai, Shanghai Municipality, China, 200025
        • Completed
        • Local Institution - 0223
    • Zhejiang
      • Hangzhou, Zhejiang, China, 310016
        • Recruiting
        • Sir Run Run Shaw Hospital
        • Contact:
          • Enguo Chen, Site 0304
          • Phone Number: 13588706779
  • Czechia
      • Brno, Czechia, 656 53
        • Withdrawn
        • Local Institution - 0371
      • Hradec Králové, Czechia, 500 05
        • Recruiting
        • FNHK Klinika onkologie a radioterapie
        • Contact:
          • Jindrich Kopecky, Site 0243
          • Phone Number: +420495832176
      • Olomouc, Czechia, 779 00
        • Withdrawn
        • Local Institution - 0150
      • Prague, Czechia, 128 00
        • Completed
        • Local Institution - 0275
      • Prague, Czechia, 11000
        • Withdrawn
        • Local Institution - 0253
  • Denmark
      • Odense C, Denmark, 5000
        • Withdrawn
        • Local Institution
  • Finland
      • Helsinki, Finland, 00029
        • Withdrawn
        • Local Institution
  • France
      • Clermont-Ferrand, France, 63011
        • Recruiting
        • Centre Jean Perrin
        • Contact:
          • Hakim Mahammedi, Site 0345
          • Phone Number: 33473278131
      • Créteil, France, 94010
        • Completed
        • Local Institution - 0107
      • Dijon, France, 21000
        • Completed
        • Local Institution - 0074
      • Dijon, France, 21079
        • Completed
        • Local Institution - 0109
      • La Tronche, France, 38700
        • Recruiting
        • CHU Grenobles Alpes
        • Contact:
          • Julie Charles, Site 0010
          • Phone Number: +33476766493
      • Lille, France, 59037
        • Recruiting
        • Pole Biologie Pathologie Genetique - CHU de Lille
        • Contact:
          • Laurent Mortier, Site 0011
      • Marseille, France, 13385
        • Recruiting
        • APHM - Hôpital de la Timone
        • Contact:
          • Caroline Gaudy, Site 0125
          • Phone Number: 33491387991
      • Marseille, France, 13915
        • Completed
        • Local Institution - 0153
      • Montpellier, France, 34090
        • Recruiting
        • CHU Montpellier
        • Contact:
          • Franciane PAUL, Site 0182
      • Montpellier, France, 34295
        • Withdrawn
        • Local Institution
      • Nantes, France, 44093
        • Withdrawn
        • Local Institution - 0300
      • Nantes, France, 44093
        • Completed
        • Local Institution - 0341
      • Paris, France, 75018
        • Withdrawn
        • Local Institution - 0301
      • Paris, France, 75010
        • Completed
        • Local Institution - 0028
      • Paris, France, 75908
        • Completed
        • Local Institution - 0167
      • Pierre-Bénite, France, 69495
        • Recruiting
        • Centre Hospitalier Lyon Sud
        • Contact:
          • Stephane Dalle, Site 0084
          • Phone Number: 3333478861679
      • Rennes, France, 35033
        • Withdrawn
        • Local Institution
      • Saint-Priest-en-Jarez, France, 42270
        • Recruiting
        • CHU de Saint-Étienne - Hôpital Nord
        • Contact:
          • Pierre CORNILLON, Site 0401
          • Phone Number: +477917000
      • Suresnes, France, 92151
        • Recruiting
        • Hopital Foch
        • Contact:
          • CHRISTINE ABRAHAM, Site 0392
          • Phone Number: +33676018749
      • Toulon, France, 83 056
        • Completed
        • Local Institution - 0156
      • Toulouse, France, 31059
        • Withdrawn
        • Local Institution
      • Villejuif, France, 94805
        • Recruiting
        • Institut Gustave Roussy
        • Contact:
          • Caroline Robert, Site 0029
          • Phone Number: 33142114210
    • Gironde
      • Bordeaux, Gironde, France, 33075
        • Completed
        • Local Institution - 0006
    • Meurthe-Et-Moselle
      • Vandœuvre-lès-Nancy, Meurthe-Et-Moselle, France, 54500
        • Active, not recruiting
        • Local Institution - 0362
    • Île-de-France Region
      • Paris, Île-de-France Region, France, 75005
        • Withdrawn
        • Local Institution - 0387
  • Germany
      • Aachen, Germany, 52074
        • Recruiting
        • Universitaetsklinikum Aachen
        • Contact:
          • Matthias Saar, Site 0163
          • Phone Number: 0049241800
      • Berlin, Germany, 10117
        • Completed
        • Local Institution - 0248
      • Buxtehude, Germany, 21614
        • Completed
        • Local Institution - 0249
      • Cologne, Germany, 50937
        • Withdrawn
        • Local Institution
      • Cologne, Germany, 50937
        • Withdrawn
        • Local Institution - 0296
      • Freiburg im Breisgau, Germany, 79106
        • Recruiting
        • University of Freiburg
        • Contact:
          • Roland Roelz, Site 0315
          • Phone Number: 004976127050230
      • Gera, Germany, 07548
        • Withdrawn
        • Local Institution
      • Gera, Germany, 07548
        • Recruiting
        • SRH Wald-Klinikum Gera GmbH
        • Contact:
          • Sabine Sell, Site 0080
          • Phone Number: 493658287758
      • Göttingen, Germany, 37075
        • Completed
        • Local Institution - 0076
      • Göttingen, Germany, 37075
        • Withdrawn
        • Local Institution
      • Hamburg, Germany, 20246
        • Completed
        • Local Institution - 0241
      • Heidelberg, Germany, 69120
        • Withdrawn
        • Local Institution
      • Heidelberg, Germany, 69126
        • Recruiting
        • Thoraxklinik
        • Contact:
          • Helge Bischoff, Site 0148
          • Phone Number: 4962213961304
      • Heidelberg, Germany, D-69120
        • Completed
        • Local Institution - 0342
      • Heilbronn, Germany, 74078
        • Recruiting
        • SLK-Kliniken Heilbronn GmbH
        • Contact:
          • Uwe Martens, Site 0285
          • Phone Number: 4971314928700
      • Jena, Germany, 07747
        • Recruiting
        • Universitaetsklinikum Jena - Klinik und Poliklinik fuer Urologie
        • Contact:
          • Marc-Oliver Grimm, Site 0216
          • Phone Number: +49(0)36419329901
      • Kassel, Germany, 34125
        • Completed
        • Local Institution - 0288
      • Kiel, Germany, 24105
        • Withdrawn
        • Local Institution
      • Kiel, Germany, 24105
        • Completed
        • Local Institution - 0072
      • Löwenstein, Germany, 74245
        • Withdrawn
        • Local Institution - 0298
      • Lübeck, Germany, 23538
        • Withdrawn
        • Local Institution - 0098
      • Mainz, Germany, 55131
        • Withdrawn
        • Local Institution
      • Mainz, Germany, 55131
        • Completed
        • Local Institution - 0089
      • Tübingen, Germany, 72076
        • Completed
        • Local Institution - 0017
      • Tübingen, Germany, 72076
        • Withdrawn
        • Local Institution - 0277
    • Baden-Wurttemberg
      • Löwenstein, Baden-Wurttemberg, Germany, 74245
        • Withdrawn
        • Local Institution - 0386
    • Bavaria
      • Munich, Bavaria, Germany, 80337
        • Completed
        • Local Institution - 0276
      • Nuremberg, Bavaria, Germany, 90419
        • Withdrawn
        • Local Institution - 0332
    • North Rhine-Westphalia
      • Essen, North Rhine-Westphalia, Germany, 45147
        • Completed
        • Local Institution - 0250
      • Essen, North Rhine-Westphalia, Germany, 45147
        • Withdrawn
        • Local Institution - 0375
      • Essen, North Rhine-Westphalia, Germany, 45136
        • Recruiting
        • Evangelische Kliniken Essen Mitte. Evang. Huyssens-Stiftung Essen-Huttrop
        • Contact:
          • Sebastian Ertl, Site 0402
          • Phone Number: 4920117424001
  • Greece
      • Athens, Greece, 18547
        • Withdrawn
        • Local Institution - 0295
      • Athens, Greece, 11528
        • Completed
        • Local Institution - 0171
      • Athens, Greece, 11527
        • Completed
        • Local Institution - 0126
      • Athens, Greece, 18547
        • Completed
        • Local Institution - 0042
      • Athens, Greece, 11527
        • Completed
        • Local Institution - 0022
      • Pátrai, Greece, 26504
        • Withdrawn
        • Local Institution
      • Thessaloniki, Greece, 57001
        • Completed
        • Local Institution - 0215
    • Attica
      • Athens, Attica, Greece, 11528
        • Recruiting
        • Alexandra Hospital
        • Contact:
          • Michail Liontos, Site 0381
          • Phone Number: 3021232162845
    • Crete
      • Heraklion, Crete, Greece, 710 03
        • Withdrawn
        • Local Institution - 0244
  • Hong Kong
      • Hong Kong, Hong Kong, 000000
        • Recruiting
        • Queen Mary Hospital
        • Contact:
          • Thomas Yau, Site 0339
          • Phone Number: 85222554249
  • Hungary
      • Budapest, Hungary, 1121
        • Completed
        • Local Institution - 0159
      • Budapest, Hungary, 1121
        • Withdrawn
        • Local Institution - 0226
      • Debrecen, Hungary, 4032
        • Completed
        • Local Institution - 0187
    • Heves County
      • Gyöngyössolymos, Heves County, Hungary, 3233
        • Completed
        • Local Institution - 0290
  • Ireland
      • Dublin, Ireland, Dublin 7
        • Withdrawn
        • Local Institution - 0227
      • Limerick, Ireland, V94 F858
        • Withdrawn
        • Local Institution
  • Israel
      • Haifa, Israel, 3109601
        • Completed
        • Local Institution - 0190
      • Jerusalem, Israel, 91120
        • Completed
        • Local Institution - 0270
      • Petah Tikva, Israel, 49100
        • Withdrawn
        • Local Institution
      • Ramat Gan, Israel, 52621
        • Completed
        • Local Institution - 0052
      • Tiqwa, Israel, 49100
        • Withdrawn
        • Local Institution - 0350
  • Italy
      • Bari, Italy, 70124
        • Completed
        • Local Institution - 0034
      • Bergamo, Italy, 24127
        • Completed
        • Local Institution - 0002
      • Candiolo, Italy, 10060
        • Withdrawn
        • Local Institution - 0326
      • Catania, Italy, 95123
        • Recruiting
        • "Azienda Ospedaliero - Universitaria ""Policlinico-Vittorio Emanuele"" - Ospedale Gaspare Rodolico"
        • Contact:
          • HECTOR SOTO PARRA, Site 0359
          • Phone Number: 0953782426
      • Genova, Italy, 16132
        • Withdrawn
        • Local Institution
      • Genova, Italy, 16132
        • Completed
        • Local Institution - 0251
      • Meldola, Italy, 47014
        • Withdrawn
        • Local Institution - 0303
      • Meldola, Italy, 47014
        • Withdrawn
        • Local Institution - 0108
      • Milan, Italy, 20133
        • Withdrawn
        • Local Institution - 0351
      • Milan, Italy, 20133
        • Recruiting
        • Fondazione IRCCS istituto Neurologico Carlo Besta;
        • Contact:
          • Elena Anghileri, Site 0312
          • Phone Number: 00390223942285
      • Milan, Italy, 20133
        • Completed
        • Local Institution - 0096
      • Milan, Italy, 20133
        • Withdrawn
        • Local Institution
      • Milan, Italy, 20141
        • Completed
        • Local Institution - 0071
      • Milan, Italy, 20141
        • Withdrawn
        • Local Institution
      • Milan, Italy, 20141
        • Completed
        • Local Institution - 0267
      • Modena, Italy, 41124
        • Withdrawn
        • Local Institution - 0327
      • Naples, Italy, 80131
        • Completed
        • Local Institution - 0218
      • Naples, Italy, 80138
        • Withdrawn
        • Local Institution - 0292
      • Naples, Italy, 80131
        • Completed
        • Local Institution - 0073
      • Padova, Italy, 35128
        • Recruiting
        • Istituto Oncologico Veneto
        • Contact:
          • Umberto Basso, Site 0067
          • Phone Number: +39-049-8215953
      • Ravenna, Italy, 48121
        • Completed
        • Local Institution - 0180
      • Siena, Italy, 53100
        • Completed
        • Local Institution - 0003
      • Terni, Italy, 05100
        • Withdrawn
        • Local Institution - 0291
      • Torino, Italy, 10126
        • Recruiting
        • Azienda Ospedaliera Citta della Salute e della Scienza
        • Contact:
          • Alessia Pellerino, Site 0313
          • Phone Number: +390116334904
    • Fc
      • Meldola, Fc, Italy, 47014
        • Recruiting
        • IRCCS - Istituto Scientifico Romagnolo per lo Studio dei Tumori - Dino Amadori - Srl
        • Contact:
          • Angelo Delmonte, Site 0361
          • Phone Number: +393487469100
    • MI
      • Rozzano, MI, Italy, 20089
        • Withdrawn
        • Local Institution - 0333
    • RM
      • Roma, RM, Italy, 00144
        • Recruiting
        • Istituto Nazionale dei Tumori Regina Elena
        • Contact:
          • Michelangelo Russillo, Site 0033
          • Phone Number: 0652662745
  • Japan
      • Fukuoka, Japan, 11111
        • Withdrawn
        • Local Institution - 0224
      • Hiroshima, Japan, 7348551
        • Recruiting
        • Hiroshima University Hospital
        • Contact:
          • Tomokazu Kawaoka, Site 0319
          • Phone Number: 81822575555
      • Niigata, Japan, 951-8520
        • Completed
        • Local Institution - 0236
    • Aomori
      • Hirosaki-shi, Aomori, Japan, 036-8563
        • Completed
        • Local Institution - 0242
    • Chiba
      • Chiba, Chiba, Japan, 2608717
        • Recruiting
        • Chiba cancer center
        • Contact:
          • Atsushi Komaru, Site 0409
          • Phone Number: 81432645431
      • Kashiwa-Shi, Chiba, Japan, 2778577
        • Recruiting
        • National Cancer Center Hospital East
        • Contact:
          • Toshihiko Doi, Site 0356
          • Phone Number: 81335422511
    • Ehime
      • Matsuyama, Ehime, Japan, 7900024
        • Recruiting
        • Ehime Prefectural Central Hospital
        • Contact:
          • Fujimasa Tada, Site 0394
      • Matsuyama, Ehime, Japan, 7910280
        • Recruiting
        • National Hospital Organization Shikoku Cancer Center
        • Contact:
          • Katsuyoshi Hashine, Site 0397
          • Phone Number: 81899991111
    • Fukuoka
      • Fukuoka, Fukuoka, Japan, 812-8582
        • Recruiting
        • Kyushu University Hospital
        • Contact:
          • Takashi Matsumoto, Site 0393
          • Phone Number: 81926425603
    • Hyōgo
      • Kobe, Hyōgo, Japan, 6500047
        • Completed
        • Local Institution - 0211
    • Ibaraki
      • Tsukuba, Ibaraki, Japan, 305-8576
        • Completed
        • Local Institution - 0240
    • Ishikawa-ken
      • Kanazawa, Ishikawa-ken, Japan, 920-8641
        • Withdrawn
        • Local Institution - 0219
    • Kanagawa
      • Yokohama, Kanagawa, Japan, 2320024
        • Recruiting
        • Yokohama City University Medical Center
        • Contact:
          • Manabu Morimoto, Site 0368
          • Phone Number: 81452615656
    • Miyagi
      • Natori-shi, Miyagi, Japan, 981-1293
        • Completed
        • Local Institution - 0222
    • Niigata
      • Niigata, Niigata, Japan, 9518566
        • Completed
        • Local Institution - 0230
    • Osaka
      • Sayama, Osaka, Japan, 5898511
        • Completed
        • Local Institution - 0214
      • Takatsuki, Osaka, Japan, 569-8686
        • Completed
        • Local Institution - 0212
    • Shizuoka
      • Hamamatsu, Shizuoka, Japan, 431-3192
        • Recruiting
        • Hamamatsu University Hospital
        • Contact:
          • Teruo Inamoto, Site 0391
          • Phone Number: 0534362306
    • Tokyo
      • Adachi-Ku, Tokyo, Japan, 1238558
        • Recruiting
        • Tokyo Women's Medical University - Adachi Medical Center
        • Contact:
          • Tsunenori Kondo, Site 0406
      • Bunkyo-Ku, Tokyo, Japan, 1138519
        • Recruiting
        • Institute of Science Tokyo Hospital
        • Contact:
          • Shohei Fukuda, Site 0404
          • Phone Number: 81358035295
      • Chuo-ku, Tokyo, Japan, 1040045
        • Completed
        • Local Institution - 0235
      • Koto-Ku, Tokyo, Japan, 135-8550
        • Completed
        • Local Institution - 0217
      • Shinjuku, Tokyo, Japan, 160-8582
        • Completed
        • Local Institution - 0239
  • Mexico
      • Mexico City, Mexico, 14080
        • Recruiting
        • Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
        • Contact:
          • Maria Bourlon, Site 0344
          • Phone Number: 5215554386271
      • Mexico City, Mexico, 03810
        • Withdrawn
        • Local Institution - 0410
      • México, Mexico, 14080
        • Recruiting
        • Instituto Nacional De Cancerologia
        • Contact:
          • Nora Sobrevilla Moreno, Site 0346
          • Phone Number: 525555734772
      • San Luis Potosí City, Mexico, 78250
        • Recruiting
        • Centro Potosino de Investigacion Medica S.C.
        • Contact:
          • Pedro Figueroa Martinez, Site 0367
          • Phone Number: 4444479873
    • Guanajuato
      • León, Guanajuato, Mexico, 37000
        • Withdrawn
        • Local Institution - 0152
    • Jalisco
      • Zapopan, Jalisco, Mexico, 45070
        • Recruiting
        • Investigación Biomédica para el Desarrollo de Fármacos S.A de C.V
        • Contact:
          • EMILIO MURILLO, Site 0338
          • Phone Number: +523311938595
    • Mexico City
      • Cuauhtémoc, Mexico City, Mexico, 06100
        • Recruiting
        • Cryptex Investigacion Clinica Sa de Cv
        • Contact:
          • Daniel Motola Kuba, Site 0337
          • Phone Number: 5215585815263
      • Tlalpan, Mexico City, Mexico, 14050
        • Withdrawn
        • Local Institution - 0181
    • Michoacán
      • Morelia, Michoacán, Mexico, 58240
        • Completed
        • Local Institution - 0007
    • Nuevo León
      • Monterrey, Nuevo León, Mexico, 64040
        • Withdrawn
        • Local Institution - 0286
      • Monterrey, Nuevo León, Mexico, 64460
        • Withdrawn
        • Local Institution - 0354
      • Monterrey, Nuevo León, Mexico, 64710
        • Recruiting
        • i Can Oncology Center
        • Contact:
          • Yamil Alonso Lopez Chuken, Site 0396
    • Oaxaca
      • Oaxaca City, Oaxaca, Mexico, CP68020
        • Recruiting
        • Centro de Investigacion Clinica de Oaxaca
        • Contact:
          • Roberto Romero Diaz, Site 0369
          • Phone Number: +529512570569
    • Querétaro
      • Querétaro City, Querétaro, Mexico, 76000
        • Withdrawn
        • Local Institution - 0343
  • Netherlands
      • Rotterdam, Netherlands, 3015 CE
        • Withdrawn
        • Local Institution
    • North Holland
      • Amsterdam, North Holland, Netherlands, 1066 CX
        • Withdrawn
        • Local Institution - 0335
  • New Zealand
      • Auckland, New Zealand, 1142
        • Recruiting
        • Auckland City Hospital
        • Contact:
          • Edward Gane, Site 0370
          • Phone Number: 6921548371
      • Christchurch, New Zealand, 8011
        • Withdrawn
        • Local Institution - 0271
      • Dunedin, New Zealand, 9016
        • Completed
        • Local Institution - 0268
      • Tauranga, New Zealand, 3112
        • Completed
        • Local Institution - 0269
  • Norway
      • Bergen, Norway, 5021
        • Completed
        • Local Institution - 0213
      • Oslo, Norway, N-0379
        • Completed
        • Local Institution - 0048
  • Peru
      • Lima, Peru, 15076
        • Not yet recruiting
        • Local Institution - 0385
        • Contact:
          • Site 0385
    • Lima region
      • Santiago de Surco, Lima region, Peru, 15023
        • Completed
        • Local Institution - 0179
  • Poland
      • Biała Podlaska, Poland, 21-500
        • Withdrawn
        • Local Institution - 0336
      • Gdansk, Poland, 80219
        • Recruiting
        • Wojewodzkie Centrum Onkologii
        • Contact:
          • Joanna Wojcik-Tomaszewska, Site 0069
          • Phone Number: 4858505993747
      • Gdansk, Poland, 80-214
        • Completed
        • Local Institution - 0120
      • Krakow, Poland, 31-501
        • Withdrawn
        • Local Institution - 0373
      • Krakow, Poland, 30-510
        • Withdrawn
        • Local Institution - 0377
      • Krakow, Poland, 31-115
        • Completed
        • Local Institution - 0252
      • Lodz, Poland, 90-302
        • Recruiting
        • Instytut MSF Sp zoo
        • Contact:
          • Ewa Kalinka, Site 0031
      • Lublin, Poland, 20-064
        • Completed
        • Local Institution - 0118
      • Poznan, Poland, 60-185
        • Completed
        • Local Institution - 0178
      • Warsaw, Poland, 02-781
        • Withdrawn
        • Local Institution
      • Warsaw, Poland, 0 4-141
        • Recruiting
        • Wojskowy Instytut Medyczny
        • Contact:
          • Renata Duchnowska, Site 0132
          • Phone Number: +48602609988
      • Warsaw, Poland, 02-776
        • Withdrawn
        • Local Institution - 0328
      • Warsaw, Poland, 02-781
        • Recruiting
        • Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
        • Contact:
          • Dariusz Kowalski, Site 0151
          • Phone Number: 48225463066
    • Kuyavian-Pomeranian Voivodeship
      • Bydgoszcz, Kuyavian-Pomeranian Voivodeship, Poland, 85-796
        • Recruiting
        • Centrum Onkologii im. Prof. Franciszka Lukaszczyka
        • Contact:
          • Bogdan Zurawski, Site 0358
          • Phone Number: +48501446778
    • Warmian-Masurian Voivodeship
      • Olsztyn, Warmian-Masurian Voivodeship, Poland, 10-357
        • Recruiting
        • Warminsko-Mazurskie Centrum Chorob Pluc w Olsztynie
        • Contact:
          • Andrzej Kazarnowicz, Site 0414
          • Phone Number: 48895322973
  • Portugal
      • Lisbon, Portugal, 4200-072
        • Completed
        • Local Institution - 0177
      • Lisbon, Portugal, 1769-001
        • Completed
        • Local Institution - 0184
      • Porto, Portugal, 4200319
        • Withdrawn
        • Local Institution - 0142
  • Puerto Rico
      • San Juan, Puerto Rico, 918
        • Not yet recruiting
        • Local Institution - 0416
        • Contact:
          • Site 0416
    • PR
      • San Juan, PR, Puerto Rico, 00927
        • Recruiting
        • FDI Clinical Research
        • Contact:
          • Mirelis Acosta-Rivera, Site 0334
          • Phone Number: 7877520003545
  • Romania
      • Bucharest, Romania, 022328
        • Recruiting
        • Institutul Oncologic Bucuresti IOB
        • Contact:
          • Aurelia Alexandru, Site 0129
          • Phone Number: 40723289606
      • Cluj-Napoca, Romania, 400015
        • Completed
        • Local Institution - 0189
      • Cluj-Napoca, Romania, 400-641
        • Completed
        • Local Institution - 0127
      • Cluj-Napoca, Romania, 400015
        • Recruiting
        • Institutul Oncologic Prof. Dr. I. Chiricuta
        • Contact:
          • Tudor Ciuleanu, Site 0135
          • Phone Number: 40745646368
      • Oradea, Romania, 410469
        • Completed
        • Local Institution - 0133
      • Suceava, Romania, 720214
        • Recruiting
        • Sc Sigmedical Srl
        • Contact:
          • Doina Ganea, Site 0374
          • Phone Number: +40722423653
    • Dolj
      • Craiova, Dolj, Romania, 200508
        • Recruiting
        • Onco Clinic Consult SA
        • Contact:
          • Patricia Visan, Site 0378
          • Phone Number: +40724280084
      • Craiova, Dolj, Romania, 200542
        • Recruiting
        • Centrul de Oncologie Sf Nectarie
        • Contact:
          • Michael Schenker, Site 0265
          • Phone Number: 40727774974
    • Sector 2
      • Bucharest, Sector 2, Romania, 021389
        • Completed
        • Local Institution - 0310
  • Russia
      • Krasnoyarsk, Russia, 660133
        • Withdrawn
        • Local Institution - 0256
      • Moscow, Russia, 115478
        • Terminated
        • N.N. Blokhin National Medical Research Center of Oncology
      • Moscow, Russia, 121309
        • Terminated
        • VitaMed LLC
    • Krasnodarskiy Kray
      • Krasnodar, Krasnodarskiy Kray, Russia, 350040
        • Withdrawn
        • Local Institution - 0257
  • South Korea
      • Gyeonggi-do, South Korea, 10408
        • Recruiting
        • National Cancer Center
        • Contact:
          • BoHyun Kim, Site 0320
      • Seongnam-si, South Korea, 463-707
        • Completed
        • Local Institution - 0221
      • Seoul, South Korea, 03722
        • Completed
        • Local Institution - 0206
      • Seoul, South Korea, 110 - 744
        • Completed
        • Local Institution - 0324
      • Suwon, South Korea, 16499
        • Completed
        • Local Institution - 0207
    • Gyeonggi-do
      • Seongnam-si, Gyeonggi-do, South Korea, 13532
        • Withdrawn
        • Local Institution - 0389
    • Songpa-gu
      • Seoul, Songpa-gu, South Korea, 05505
        • Recruiting
        • Asan Medical Center
        • Contact:
          • Min-Hee Ryu, Site 0322
          • Phone Number: 82230105935
  • Spain
      • A Coruña, Spain, 15006
        • Completed
        • Local Institution - 0122
      • A Coruña, Spain, 15706
        • Withdrawn
        • Local Institution - 0382
      • Alicante, Spain, 03010
        • Completed
        • Local Institution - 0173
      • Badalona, Spain, 08916
        • Recruiting
        • Catalan Institute of Badalona Hospital Germans Trias i Pujol ICO
        • Contact:
          • Enric Carcereny, Site 0123
          • Phone Number: 34934978925
      • Barcelona, Spain, 08036
        • Recruiting
        • Hospital Clinic De Barcelona
        • Contact:
          • Maria Reig, Site 0323
          • Phone Number: 34932279803
      • Barcelona, Spain, 08025
        • Recruiting
        • Hospital De La Santa Creu I Sant Pau
        • Contact:
          • Margarita Majem Tarruella, Site 0384
          • Phone Number: 34935565651
      • Barcelona, Spain, 08035
        • Recruiting
        • Hospital Universitari Vall d Hebron
        • Contact:
          • Eva Munoz, Site 0091
          • Phone Number: +34932746085
      • Barcelona, Spain, 8025
        • Withdrawn
        • Local Institution
      • Barcelona, Spain, 08036
        • Completed
        • Local Institution - 0026
      • Barcelona, Spain, 08908
        • Completed
        • Local Institution - 0225
      • Burgos, Spain, 09006
        • Completed
        • Local Institution - 0146
      • Granada, Spain, 18014
        • Withdrawn
        • Local Institution - 0144
      • Madrid, Spain, 28041
        • Recruiting
        • Hospital Universitario 12 de Octubre
        • Contact:
          • Luis Paz-Ares Rodriguez, Site 0116
          • Phone Number: 3491434914692313
      • Madrid, Spain, 28040
        • Recruiting
        • Hospital Universitario Fundacion Jimenez Diaz
        • Contact:
          • Manuel Domine Gomez, Site 0112
          • Phone Number: 34915504800
      • Madrid, Spain, 28050
        • Recruiting
        • Hospital Universitario HM Sanchinarro
        • Contact:
          • Juan Rodriguez Moreno, Site 0097
          • Phone Number: 34917567984
      • Madrid, Spain, 28027
        • Recruiting
        • Clinica Universidad de Navarra Madrid
        • Contact:
          • Ignacio Melero Bermejo, Site 0360
          • Phone Number: 34948255400
      • Madrid, Spain, 28007
        • Withdrawn
        • Local Institution - 0273
      • Madrid, Spain, 28033
        • Withdrawn
        • Local Institution
      • Madrid, Spain, 28046
        • Withdrawn
        • Local Institution
      • Madrid, Spain, 28009
        • Withdrawn
        • Local Institution - 0357
      • Madrid, Spain, 28033
        • Completed
        • Local Institution - 0008
      • Madrid, Spain, 28034
        • Completed
        • Local Institution - 0027
      • Madrid, Spain, 28046
        • Active, not recruiting
        • Local Institution - 0380
      • Málaga, Spain, 29010
        • Completed
        • Local Institution - 0192
      • Santa Cruz de Tenerife, Spain, 38230
        • Withdrawn
        • Local Institution
      • Santander, Spain, 39008
        • Recruiting
        • Hospital Universitario Marques de Valdecilla
        • Contact:
          • Ignacio Jose Duran Martinez, Site 0352
          • Phone Number: 34942202515
      • Seville, Spain, 41009
        • Completed
        • Local Institution - 0274
      • Seville, Spain, 41013
        • Completed
        • Local Institution - 0294
      • Valencia, Spain, 46014
        • Recruiting
        • Hospital General Universitario de Valencia
        • Contact:
          • Alfonso Berrocal, Site 0020
      • Valencia, Spain, 46026
        • Recruiting
        • Hospital Universitario y Politecnico de la Fe
        • Contact:
          • Oscar Juan Vidal, Site 0117
          • Phone Number: 34961245877
    • Guipuzcoa
      • Donostia / San Sebastian, Guipuzcoa, Spain, 20014
        • Completed
        • Local Institution - 0047
    • Madrid
      • Majadahonda, Madrid, Spain, 28220
        • Completed
        • Local Institution - 0287
    • Navarre
      • Pamplona, Navarre, Spain, 31008
        • Recruiting
        • Clinica Universidad de Navarra
        • Contact:
          • Ignacio Melero Bermejo, Site 0353
          • Phone Number: 34948255400
  • Sweden
      • Gothenburg, Sweden, SE-41345
        • Withdrawn
        • Local Institution
      • Malmö, Sweden, 205 02
        • Withdrawn
        • Local Institution - 0036
      • Umeå, Sweden, 901 85
        • Withdrawn
        • Local Institution
  • Switzerland
      • Basel, Switzerland, 4031
        • Completed
        • Local Institution - 0119
      • Sankt Gallen, Switzerland, 9007
        • Withdrawn
        • Local Institution - 0403
      • Zurich, Switzerland, CH - 8058
        • Completed
        • Local Institution - 0083
  • Taiwan
      • Taichung, Taiwan, 40705
        • Recruiting
        • Taichung Veterans General Hospital
        • Contact:
          • Teng-Yu Lee, Site 0388
          • Phone Number: 8864235925253309
      • Tainan, Taiwan, 704
        • Completed
        • Local Institution - 0197
      • Taipei, Taiwan, 11217
        • Recruiting
        • Taipei Veterans General Hospital TPVGH
        • Contact:
          • Yi-Hsiang Huang, Site 0366
          • Phone Number: +886938590872
      • Taipei, Taiwan, 10002
        • Completed
        • Local Institution - 0412
  • Turkey (Türkiye)
      • Ankara, Turkey (Türkiye), 06010
        • Withdrawn
        • Local Institution - 0330
  • United Kingdom
      • Glasgow, United Kingdom, G12 0YN
        • Withdrawn
        • Local Institution - 0259
    • Greater London
      • London, Greater London, United Kingdom, NW1 2PG
        • Recruiting
        • University College Hospital
        • Contact:
          • Paul Mulholland, Site 0314
          • Phone Number: 000-000-0000
      • London, Greater London, United Kingdom, SW3 6JJ
        • Completed
        • Local Institution - 0086
      • London, Greater London, United Kingdom, SM2 5PT
        • Completed
        • Local Institution - 0272
      • London, Greater London, United Kingdom, N18 1QX
        • Completed
        • Local Institution - 0141
    • Greater Manchester
      • Manchester, Greater Manchester, United Kingdom, M20 4BX
        • Completed
        • Local Institution - 0115
    • Hampshire
      • Southampton, Hampshire, United Kingdom, SO16 6YD
        • Completed
        • Local Institution - 0195
    • Kent
      • Maidstone, Kent, United Kingdom, ME16 9QQ
        • Withdrawn
        • Local Institution - 0231
    • Middlesex
      • Northwood, Middlesex, United Kingdom, HA6 2RN
        • Completed
        • Local Institution - 0161
    • Scotland
      • Edinburgh, Scotland, United Kingdom, EH4 2XU
        • Withdrawn
        • Local Institution - 0299
  • United States
    • Alabama
      • Huntsville, Alabama, United States, 35801
        • Completed
        • Local Institution - 0220
    • Arizona
      • Tucson, Arizona, United States, 85724
        • Withdrawn
        • University of Arizona College of Medicine
    • California
      • Lynwood, California, United States, 90262
        • Withdrawn
        • Innovative Clinical Research Institute
      • San Francisco, California, United States, 94115
        • Withdrawn
        • Local Institution
      • San Francisco, California, United States, 94143
        • Completed
        • Local Institution - 0099
    • Colorado
      • Aurora, Colorado, United States, 80045
        • Completed
        • Local Institution - 0233
    • Connecticut
      • New Haven, Connecticut, United States, 06520
        • Withdrawn
        • Local Institution - 0095
    • District of Columbia
      • Washington D.C., District of Columbia, United States, 20007-2113
        • Completed
        • Local Institution - 0088
    • Florida
      • Ocala, Florida, United States, 34474
        • Withdrawn
        • Florida Cancer Affiliates
      • Orlando, Florida, United States, 32806
        • Withdrawn
        • Local Institution
      • Tampa, Florida, United States, 33612
        • Completed
        • Local Institution - 0024
    • Illinois
      • Chicago, Illinois, United States, 60637
        • Completed
        • Local Institution - 0105
      • Maywood, Illinois, United States, 60153
        • Withdrawn
        • Local Institution
      • Park Ridge, Illinois, United States, 60068
        • Completed
        • Local Institution - 0279
    • Kansas
      • Westwood, Kansas, United States, 66205
        • Completed
        • Local Institution - 0186
      • Wichita, Kansas, United States, 67214-3728
        • Completed
        • Local Institution - 0165
    • Kentucky
      • Louisville, Kentucky, United States, 40202
        • Recruiting
        • University of Louisville-James Graham Brown Cancer Center
        • Contact:
          • Jason Chesney, Site 0059
          • Phone Number: 502-562-2280
    • Maryland
      • Baltimore, Maryland, United States, 21287
        • Completed
        • Local Institution - 0092
    • Massachusetts
      • Boston, Massachusetts, United States, 02215
        • Recruiting
        • Dana_Farber Cancer Institute (DFCI)
        • Contact:
          • David Reardon, Site 0082
          • Phone Number: 617-632-2166
      • Boston, Massachusetts, United States, 02215
        • Withdrawn
        • Local Institution - 0081
      • Boston, Massachusetts, United States, 02114
        • Completed
        • Local Institution - 0039
    • Michigan
      • Ann Arbor, Michigan, United States, 48109-5008
        • Completed
        • Local Institution - 0143
    • Minnesota
      • Minneapolis, Minnesota, United States, 55407-3723
        • Completed
        • Local Institution - 0100
    • Missouri
      • St Louis, Missouri, United States, 63110
        • Withdrawn
        • Local Institution
    • Nebraska
      • Omaha, Nebraska, United States, 68130
        • Completed
        • Local Institution - 0205
    • New Hampshire
      • Lebanon, New Hampshire, United States, 03756
        • Completed
        • Local Institution - 0014
    • New Mexico
      • Albuquerque, New Mexico, United States, 87131
        • Withdrawn
        • Local Institution
    • New York
      • Buffalo, New York, United States, 14263
        • Recruiting
        • Roswell Park Cancer Institute
        • Contact:
          • Saby George, Site 0128
          • Phone Number: 716-845-8387
      • Mineola, New York, United States, 11501
        • Recruiting
        • NYU Langone Hematology Oncology Associates-Mineola
        • Contact:
          • Jeffery Schneider, Site 0413
          • Phone Number: 516-578-2408
      • New York, New York, United States, 10065
        • Withdrawn
        • Local Institution
      • New York, New York, United States, 10016
        • Withdrawn
        • Local Institution
      • New York, New York, United States, 10065
        • Completed
        • Local Institution - 0185
      • New York, New York, United States, 10065
        • Withdrawn
        • Local Institution - 0202
    • North Carolina
      • Charlotte, North Carolina, United States, 28204
        • Completed
        • Local Institution - 0204
      • Durham, North Carolina, United States, 27705
        • Completed
        • Local Institution - 0016
    • Ohio
      • Cincinnati, Ohio, United States, 45242
        • Recruiting
        • Oncology Hematology Care
        • Contact:
          • Patrick Ward, Site 0085
          • Phone Number: 513-751-2273
      • Cincinnati, Ohio, United States, 45267
        • Active, not recruiting
        • Local Institution - 0408
      • Cleveland, Ohio, United States, 44106
        • Withdrawn
        • Local Institution
      • Columbus, Ohio, United States, 43210
        • Recruiting
        • The Ohio University
        • Contact:
          • Asrar Alahmadi, Site 0103
          • Phone Number: 202-361-4528
    • Oklahoma
      • Tulsa, Oklahoma, United States, 74146
        • Withdrawn
        • Local Institution - 0246
    • Pennsylvania
      • Allentown, Pennsylvania, United States, 18103
        • Completed
        • Local Institution - 0037
      • Easton, Pennsylvania, United States, 18045
        • Completed
        • Local Institution - 0054
      • Lancaster, Pennsylvania, United States, 17601
        • Recruiting
        • Lancaster General Health
        • Contact:
          • Samuel Kerr, Site 0400
          • Phone Number: 717-215-9561
      • Natrona Heights, Pennsylvania, United States, 15065
        • Withdrawn
        • Allegheny Valley Hospital
      • Philadelphia, Pennsylvania, United States, 19104
        • Withdrawn
        • Local Institution
      • Philadelphia, Pennsylvania, United States, 19111
        • Withdrawn
        • Local Institution - 0162
      • Pittsburgh, Pennsylvania, United States, 15213
        • Completed
        • Local Institution - 0110
    • South Carolina
      • Charleston, South Carolina, United States, 29414
        • Completed
        • Local Institution - 0228
      • Greenville, South Carolina, United States, 29615
        • Withdrawn
        • Local Institution
    • Tennessee
      • Chattanooga, Tennessee, United States, 37404
        • Withdrawn
        • Local Institution
      • Nashville, Tennessee, United States, 37232
        • Withdrawn
        • Vanderbilt University Medical Center
      • Nashville, Tennessee, United States, 37203
        • Recruiting
        • Tennesse Oncology
        • Contact:
          • David Spigel, Site 0130
          • Phone Number: 615-320-5090
    • Texas
      • Dallas, Texas, United States, 75390
        • Withdrawn
        • Local Institution
      • Houston, Texas, United States, 77030-4000
        • Withdrawn
        • Local Institution - 0364
    • Utah
      • Salt Lake City, Utah, United States, 84112-5550
        • Completed
        • Local Institution - 0055
    • Virginia
      • Charlottesville, Virginia, United States, 22908
        • Withdrawn
        • Local Institution
    • Washington
      • Renton, Washington, United States, 98055
        • Withdrawn
        • Public Hospital of King County District 1 Valley Medical Center
    • Wisconsin
      • Madison, Wisconsin, United States, 53792
        • Withdrawn
        • Local Institution - 0124
      • Madison, Wisconsin, United States, 53792
        • Completed
        • Local Institution - 0065

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Description

Inclusion Criteria

  • Signed Written Informed Consent.
  • Eligible to receive continued study treatment per the Parent Study, including treatment beyond progression per investigator assessment in the Parent Study.
  • On treatment hold in the Parent Study following long-lasting response or are eligible for treatment rechallenge as defined in the Parent Study.
  • WOCBP and male participants who are sexually active must agree to follow instructions for method(s) of contraception as described below and included in the ICF.

Exclusion Criteria

  • Participant is not eligible for study treatment per the Parent Study eligibility criteria.
  • Participants not receiving clinical benefit as assessed by the Investigator.
  • Any clinical adverse event (AE), laboratory abnormality, or intercurrent illness which, in the opinion of the Investigator, indicates that participation in the study is not in the best interest of the participant.
  • Other protocol-defined Inclusion/Exclusion Criteria apply

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: A1: Nivolumab Monotherapy Dose 1
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Experimental: A2: Nivolumab Monotherapy Dose 2
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Experimental: B1: Nivolumab + Ipilimumab
Drug: Ipilimumab
Specified dose on specified days
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Experimental: B2: Nivolumab + Ipilimumab + Cabozantinib
Drug: Ipilimumab
Specified dose on specified days
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Cabozantinib
Specified dose on specified days
Experimental: B3: Nivolumab + Ipilimumab + Trametinib
Drug: Trametinib
Specified dose on specified days
Drug: Ipilimumab
Specified dose on specified days
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Experimental: C1: Relatlimab + Nivolumab Fixed Dose Combination Dose 1
Drug: Nivolumab + Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986213
Experimental: C3: Relatlimab + Nivolumab Fixed Dose Combination Dose 2
Drug: Nivolumab + Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986213
Experimental: C2: Relatlimab + Nivolumab Single Agent Vial (SAV) Dose 1
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986016-01
Experimental: C4: Relatlimab + Nivolumab SAV Dose 2
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986016-01
Experimental: C5: Relatlimab + Nivolumab + Ipilimumab
Drug: Ipilimumab
Specified dose on specified days
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Experimental: C6: Relatlimab + Nivolumab + Capecitabine
Drug: Capecitabine
Specified dose on specified days
Drug: Nivolumab + Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986213
Experimental: C7: Relatlimab + Nivolumab SAV Dose 3
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986016-01
Experimental: C10: Relatlimab + Nivolumab SAV Dose 4
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986016-01
Experimental: C12: Relatlimab + Nivolumab SAV Dose 5
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986016-01
Experimental: C8: Relatlimab + Nivolumab SAV + PDCT Dose 1
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986016-01
Experimental: C9: Relatlimab + Nivolumab SAV + Bevacizumab
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Bevacizumab
Specified dose on specified days
Drug: Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986016-01
Experimental: C11: Relatlimab + Nivolumab SAV + PDCT Dose 2
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Relatlimab
Specified dose on specified days
Other Names:
  • BMS-986016-01
Experimental: D1: Nivolumab + Temozolomide
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Temozolomide
Specified dose on specified days
Experimental: D2: Nivolumab + Rucaparib
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Rucaparib
Specified dose on specified days
Experimental: D3: Nivolumab + Daratumumab
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Drug: Daratumumab
Specified dose on specified days
Experimental: D4: Nivolumab + Bevacizumab
Drug: Nivolumab
Specified dose on specified days
Other Names:
  • BMS-936558-01
Experimental: E1: Bevacizumab Monotherapy
Drug: Bevacizumab
Specified dose on specified days
Experimental: E2: Regorafinib Monotherapy
Drug: Regorafinib
Specified dose on specified days
Experimental: E4: Leucovorin + Oxaliplatin + Fluorouracil
Drug: Fluorouracil
Specified dose on specified days
Drug: Oxaliplatin
Specified dose on specified days
Drug: Leucovorin
Specified dose on specified days
Experimental: E5: Enzalutamide Monotherapy
Drug: Enzalutamide
Specified dose on specified days
Experimental: E6: Sunitinib Monotherapy
Drug: Sunitinib
Specified dose on specified days
Experimental: E7: Rucaparib Monotherapy
Drug: Rucaparib
Specified dose on specified days
Experimental: E8: Capecitabine Monotherapy
Drug: Capecitabine
Specified dose on specified days
Experimental: E9: Cabozantinib Monotherapy
Drug: Cabozantinib
Specified dose on specified days
Experimental: E10: Pemetrexed Monotherapy
Drug: Pemetrexed
Specified dose on specified days
Experimental: E11: Pembrolizumab Monotherapy
Drug: Pembrolizumab
Specified dose on specified days
Experimental: E3: Leucovorin + Fluorouracil
Drug: Leucovorin
Specified dose on specified days

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Incidence of Adverse Events (AEs)
Time Frame: From Day 1 up to 135 Days after discontinuation of treatment
From Day 1 up to 135 Days after discontinuation of treatment
Incidence of drug related AEs
Time Frame: From Day 1 up to 135 Days after discontinuation of treatment
From Day 1 up to 135 Days after discontinuation of treatment
Incidence of AEs leading to Discontinuation
Time Frame: From Day 1 up to 135 Days after discontinuation of treatment
From Day 1 up to 135 Days after discontinuation of treatment
Incidence of Serious Adverse Events (SAEs)
Time Frame: From signature of Informed Consent up to 135 Days after discontinuation of treatment
From signature of Informed Consent up to 135 Days after discontinuation of treatment
Incidence of Select AEs
Time Frame: From Day 1 up to 135 Days after discontinuation of treatment
From Day 1 up to 135 Days after discontinuation of treatment
Incidence of Immune-Mediated AEs
Time Frame: From Day 1 up to 135 Days after discontinuation of treatment
From Day 1 up to 135 Days after discontinuation of treatment
Incidence of Death
Time Frame: From signature of Informed Consent up to 135 Days after discontinuation of treatment
From signature of Informed Consent up to 135 Days after discontinuation of treatment

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Bristol-Myers Squibb

Collaborators

Novartis
Clovis Oncology, Inc.
Janssen Pharmaceuticals
Exelixis

Investigators

  • Study Director: Bristol-Myers Squibb, Bristol-Myers Squibb

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 9, 2019

Primary Completion (Estimated)

August 25, 2029

Study Completion (Estimated)

August 25, 2029

Study Registration Dates

First Submitted

April 1, 2019

First Submitted That Met QC Criteria

April 1, 2019

First Posted (Actual)

April 2, 2019

Study Record Updates

Last Update Posted (Actual)

June 3, 2026

Last Update Submitted That Met QC Criteria

June 2, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • CA209-8TT
  • 2018-004362-34 (EudraCT Number)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

BMS will provide access to individual anonymized participant data upon request from qualified researchers, and subject to certain criteria. Additional information regarding Bristol Myer Squibb's data sharing policy and process can be found at https://www.bms.com/researchers-and-partners/clinical-trials-and-research.html

IPD Sharing Time Frame

See Plan Description

IPD Sharing Access Criteria

See Plan Description

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL
  • SAP
  • CSR

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

Yes

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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