Observational Study of Patients With Moderate to Severe Chronic Plaque Psoriasis (VALUE)

Multi-Country Prospective ObserVAtionaL, Cohort Study of Patients With Moderate to Severe Chronic PlaqUE Psoriasis (VALUE)

This study will assess the use of risankizumab in adult patients with moderate to severe chronic plaque psoriasis and compare risankizumab to other commonly used biologics.

Study Overview

• Status: Completed
• Conditions: Chronic Plaque Psoriasis

• Study Type: Observational
• Enrollment (Actual): 2759

Contacts and Locations

Study Locations

• Argentina
  • Buenos Aires, Argentina, 1024
    • Professional Skin Care /ID# 218514
  • CABA, Argentina, C1199ABB
    • Hospital Italiano /ID# 217000
  • Buenos Aires
    • Lomas de Zamora, Buenos Aires, Argentina, 1832
      • Emiliano Baccarini Priv Practice /ID# 218581
    • Pilar, Buenos Aires, Argentina, 1629
      • Hospital Universitario Austral /ID# 217540
  • Buenos Aires F.D.
    • Ciudad Autonoma Buenos Aires, Buenos Aires F.D., Argentina, 1114
      • Stringa Dermatologia /ID# 218450
    • Ciudad Autonoma Buenos Aires, Buenos Aires F.D., Argentina, 1425
      • Private Office Cristina Echeverria /ID# 222082
    • Ciudad Autonoma de Buenos Aire, Buenos Aires F.D., Argentina, 1023
      • Stat Research /ID# 217185
    • Ciudad Autonoma de Buenos Aire, Buenos Aires F.D., Argentina, 1055
      • Buenos Aires Skin /ID# 217657
    • Ciudad Autonoma de Buenos Aire, Buenos Aires F.D., Argentina, 1425
      • CEDIC Centro de Investigaciones Clinicas /ID# 217184
    • Ciudad Autonoma de Buenos Aire, Buenos Aires F.D., Argentina, 1425
      • Instituto de Neumonologia y Dermatologia /ID# 217429
    • Ciudad Autonoma de Buenos Aire, Buenos Aires F.D., Argentina, 1425
      • Psoriahue Med Interdisciplinar /ID# 217182
• Australia
  • New South Wales
    • Kogarah, New South Wales, Australia, 2217
      • Premier Specialist /ID# 218158
    • Miranda, New South Wales, Australia, 2228
      • Kingsway Dermatology & Aesthetics /ID# 217616
  • Queensland
    • Chermside, Queensland, Australia, 4032
      • Northern Dermatology /ID# 218374
    • Woolloongabba, Queensland, Australia, 4102
      • Veracity Clinical Research /ID# 217618
  • Victoria
    • Carlton, Victoria, Australia, 3053
      • Skin Health Institute Inc /ID# 217619
  • Western Australia
    • Fremantle, Western Australia, Australia, 6160
      • Fremantle Dermatology /ID# 217617
• Austria
  • Hainfeld, Austria, 3170
    • Haut Trattner Dermatologie /ID# 216138
  • Styria
    • Graz, Styria, Austria, 8010
      • Medizinische Universitaet Graz /ID# 217702
  • Upper Austria
    • Wels, Upper Austria, Austria, 4600
      • Klinikum Wels-Grieskirchen GmbH /ID# 216140
  • Vienna
    • Vienna, Vienna, Austria, 1030
      • Klinik Landstrasse /ID# 217684
    • Vienna, Vienna, Austria, 1100
      • Medizin am Hauptbahnhof /ID# 218837
    • Vienna, Vienna, Austria, 1130
      • EZW HAUT Entzuendungszentrum Wien /ID# 215488
    • Vienna, Vienna, Austria, 1130
      • Klinik Hietzing /ID# 217685
    • Vienna, Vienna, Austria, 1220
      • Klinik Donaustadt /ID# 218842
  • Vorarlberg
    • Dornbirn, Vorarlberg, Austria, 6850
      • Hautarzt Dr. Lukas Kraus /ID# 216139
• Canada
  • Alberta
    • Calgary, Alberta, Canada, T3A 2N1
      • Beacon Dermatology Inc /ID# 213524
    • Edmonton, Alberta, Canada, T6G 1C3
      • Alberta DermaSurgery Centre /ID# 230114
    • Edmonton, Alberta, Canada, T5K 1X3
      • Duplicate_Stratica Medical /ID# 213526
  • British Columbia
    • Vancouver, British Columbia, Canada, V5Z 3N9
      • University of British Columbia - Eye Care Centre, Vancouver General Hospital /ID# 213507
  • Manitoba
    • Brandon, Manitoba, Canada, R7A 0L5
      • SKIN Clinics /ID# 213082
    • Winnipeg, Manitoba, Canada, R3C 0N2
      • Winnipeg Clinic /ID# 212134
  • New Brunswick
    • Fredericton, New Brunswick, Canada, E3B 1G9
      • Dr. Irina Turchin PC Inc. /ID# 212128
  • Newfoundland and Labrador
    • St. John's, Newfoundland and Labrador, Canada, A1A 4Y3
      • Karma Clinical Trials /ID# 213522
    • St. John's, Newfoundland and Labrador, Canada, A1C 2H5
      • NewLab Clinical Research Inc. /ID# 213521
    • St. John's, Newfoundland and Labrador, Canada, A1E 1V4
      • Dr. Brown-Maher PMC INC. /ID# 212136
  • Ontario
    • Ajax, Ontario, Canada, L1S 7K8
      • CCA Medical Research /ID# 214446
    • Barrie, Ontario, Canada, L4M 7G1
      • SimcoDerm Medical and Surgical Dermatology Center /ID# 213081
    • Hamilton, Ontario, Canada, L8L 3C3
      • LEADER Research /ID# 249701
    • Hamilton, Ontario, Canada, L8L 8E7
      • Hamilton Health Sciences Corporation /ID# 214053
    • Hamilton, Ontario, Canada, L8N 1Y2
      • Dermatrials Research /ID# 213523
    • Hamilton, Ontario, Canada, L8L 3C3
      • Lima's Excellence in Allergy and Dermatology Research Inc /ID# 231973
    • Markham, Ontario, Canada, L3P 1X2
      • Lynderm Research Inc /ID# 212124
    • Mississauga, Ontario, Canada, L4W 0C2
      • Al-Mohammedi Medicine Professional Corporation /ID# 215408
    • Mississauga, Ontario, Canada, L4Y 4C5
      • DermEdge - Queensway East /ID# 213525
    • Ottawa, Ontario, Canada, K1H 7X3
      • Angela Montgomery Medicine Professional Corporation /ID# 213615
    • Peterborough, Ontario, Canada, K9J 5K2
      • Dr Melinda Gooderham Medicine Professional Corporation /ID# 212133
    • Stoney Creek, Ontario, Canada, L8G 1H1
      • Farheen Mussani Medicine Professional Corporation /ID# 213811
    • Toronto, Ontario, Canada, M2N 3A6
      • North York Research Inc /ID# 213486
    • Waterloo, Ontario, Canada, N2J 1C4
      • Private Practice - Dr. Kim Papp Clinical Research /ID# 212130
    • Whitby, Ontario, Canada, L1N 8M7
      • Dr Maksym Breslavets Medicine Professional Corporation /ID# 213338
  • Quebec
    • Laval, Quebec, Canada, H7N 6L2
      • Clinique D /ID# 212126
    • Québec, Quebec, Canada, G1W 4R4
      • Centre de Recherche St-Louis /ID# 216325
• Colombia
  • Barranqulla, Colombia, 080016
    • Ciensalud IPS S.A.S /ID# 244608
  • Antioquia
    • Medellín, Antioquia, Colombia, 050010
      • Fundacion hospitalaria San Vicente de Paul /ID# 222680
    • Medellín, Antioquia, Colombia, 055422
      • Centro de Inmunología y Genética CIGE SAS /ID# 222685
    • Medellín, Antioquia, Colombia, 50010
      • IPS Universitaria /ID# 241832
  • Atlántico
    • Soledad, Atlántico, Colombia, 83001
      • Fundacion Hospital Universidad del Norte /ID# 223428
  • Cundinamarca
    • Bogota, Cundinamarca, Colombia, 111711
      • Sociedad de Cirugía de Bogotá- Hospital de San José /ID# 222683
    • Bogotá, Cundinamarca, Colombia, 110221
      • Caja de Compensación Familiar Cafam, Sede Centro de Atención En Salud Cafam Flor /ID# 222660
    • Bogotá, Cundinamarca, Colombia, 111511
      • Centro Dermatológico Federico Lleras Acosta E.S.E /ID# 222686
    • Zipaquirá, Cundinamarca, Colombia, 250252
      • Healthy Medical Center S.A.S /ID# 231909
• Czechia
  • Olomouc, Czechia, 779 00
    • Fakultni nemocnice Olomouc /ID# 215901
  • Prague, Czechia, 150 00
    • Duplicate_Fakultni Nemocnice v Motole /ID# 215484
  • Prague, Czechia, 100 34
    • Fakultni nemocnice Kralovske Vinohrady /ID# 233184
  • Prague, Czechia, 110 00
    • Sanatorium profesora Arenbergera /ID# 215489
  • České Budějovice, Czechia, 370 01
    • Nemocnice Ceske Budejovice a.s. /ID# 216310
  • Hradec Kralove
    • Hradec Králové, Hradec Kralove, Czechia, 500 05
      • Fakultní nemocnice Hradec Králové - Sokolská /ID# 222670
• France
  • Aix-en-Provence, France, 13616
    • CH du Pays d'AIX /ID# 216440
  • Angers, France, 49933
    • Chu Angers /Id# 216244
  • Boulogne-Billancourt, France, 92104
    • Hopital Ambroise Pare /ID# 216439
  • Cannes, France, 06400
    • Cabinet Dermatologie et Esthetique /ID# 229132
  • Chalon-sur-Saône, France, 71321
    • CH William Morey /ID# 225441
  • Epagny Metz Tessy, France, 74370
    • CH Annecy Genevois - Site Annecy /ID# 225786
  • Lorient, France, 56322
    • C.H. de Bretagne Sud /ID# 216243
  • Saint-Mandé, France, 94163
    • Hôpital d'instruction des armées Bégin /ID# 216167
  • Bouches-du-Rhone
    • Marseille, Bouches-du-Rhone, France, 13008
      • Hopital Saint Joseph /ID# 223149
  • Brittany Region
    • Rennes, Brittany Region, France, 35000
      • CHU de Rennes - PONTCHAILLOU /ID# 218248
  • Calvados
    • Caen, Calvados, France, 14033
      • CHU de CAEN - Hopital de la Cote de Nacre /ID# 216245
  • Cote-d Or
    • Dijon, Cote-d Or, France, 21000
      • CHU Dijon /ID# 216247
  • Deux-Sevres
    • Niort, Deux-Sevres, France, 79028
      • CH Georges Renon /ID# 216174
  • Drome
    • Romans-sur-Isère, Drome, France, 26100
      • Hopitaux Drome Nord /ID# 222586
    • Valence, Drome, France, 26000
      • CH Valence /ID# 225877
  • Finistere
    • Brest, Finistere, France, 29200
      • Hopital de la Cavale Blanche /ID# 216495
  • Hautes-Pyrenees
    • Tarbes, Hautes-Pyrenees, France, 65013
      • CH Bigorre - Site de la Gespe /ID# 218563
  • Isere
    • La Tronche, Isere, France, 38700
      • CHU Grenoble - Hopital Michallon /ID# 218437
  • Marne
    • Châlons-en-Champagne, Marne, France, 51000
      • Ch Chalons En Champagne /Id# 216668
  • Moselle
    • Thionville, Moselle, France, 57100
      • CHR Metz-Thionville - Hopital Bel-Air /ID# 225691
  • Pays de la Loire Region
    • St-Priest-en-Jarez, Pays de la Loire Region, France, 42270
      • Centre Hospitalier Universitaire de Saint Etienne - Hopital Nord /ID# 216663
  • Sarthe
    • Le Mans, Sarthe, France, 72037
      • Centre Hospitalier du Mans /ID# 225729
  • Savoie
    • Chambéry, Savoie, France, 73007
      • Centre Hospitalier Métropole Savoie - Site Hôpital de Chambéry /ID# 217572
  • Somme
    • Amiens, Somme, France, 80054
      • CHU Amiens-Picardie Site Sud /ID# 216170
  • Val-d Oise
    • Pontoise, Val-d Oise, France, 95300
      • CH Pontoise - Hopital René Dubos /ID# 216169
  • Var
    • Toulon, Var, France, 83800
      • Hôpital d'Instruction des Armées Sainte-Anne /ID# 218888
  • Yonne
    • Auxerre, Yonne, France, 89011
      • Ch Auxerre /Id# 216175
• Germany
  • Augsburg, Germany, 86150
    • Praxis Dr. Mihaescu /ID# 213483
  • Bad Kreuznach, Germany, 55543
    • Mauer, Bad Kreuznach, DE /ID# 224876
  • Bad Soden am Taunus, Germany, 65812
    • Hautmedizin Bad Soden /ID# 213956
  • Bergen, Germany, 18528
    • Timmel/Timm/Vorwerk, Bergen /ID# 214552
  • Berlin, Germany, 10117
    • Hasert & Hasert, Berlin, DE /ID# 213641
  • Berlin, Germany, 10247
    • Hautzentrum Friedrichshain /ID# 213981
  • Berlin, Germany, 12353
    • Weihe/Stavermann, Berlin, DE /ID# 214550
  • Berlin, Germany, 12681
    • Praxis Dr. med. Alexander Zich /ID# 245751
  • Berlin, Germany, 13507
    • Hautarztzentrum Tegel /ID# 214849
  • Blaubeuren Abbey, Germany, 89143
    • Praxis fuer Innere Medizin/Rheumatologie /ID# 213653
  • Bogen, Germany, 94327
    • Praxis T. Schadeck /ID# 213957
  • Borna, Germany, 04552
    • Barth, Borna, DE /ID# 213643
  • Bremen, Germany, 28779
    • Schwichtenberg, Bremen, DE /ID# 213650
  • Buxtehude, Germany, 21614
    • Elbe Klinikum Buxtehude /ID# 213366
  • Darmstadt, Germany, 64283
    • Praxis Herbst /ID# 222024
  • Deggendorf, Germany, 94469
    • Praxis Dr. Sbornik /ID# 213668
  • Dessau, Germany, 06842
    • Heidlas, Dessau-Rosslau, DE /ID# 217691
  • Dresden, Germany, 01219
    • Richter-Huhn, Dresden, DE /ID# 213659
  • Düren, Germany, 52349
    • Praxis Dr. Korge /ID# 213475
  • Essen, Germany, 45130
    • Dres. Cesko u. Körber /ID# 214850
  • Gelsenkirchen, Germany, 45899
    • Gemeinschaftspraxis Rietkoetter und Jablonka /ID# 213482
  • Gera, Germany, 07548
    • Praxis Dr. Lange /ID# 213984
  • Gernsbach, Germany, 76593
    • Loth, Gernsbach, DE /ID# 214848
  • Giessen, Germany, 35390
    • Hautarztpraxis Dr. Viehmann /ID# 213675
  • Gladbeck, Germany, 45964
    • Brinkmann & Partner, Gladbeck, /ID# 214247
  • Hamburg, Germany, 22303
    • Goldbek Medical /ID# 214570
  • Hamburg, Germany, 20246
    • Universitaetsklinikum Hamburg-Eppendorf /ID# 222464
  • Hamburg, Germany, 20354
    • Dermatologikum Hamburg /ID# 213978
  • Haßfurt, Germany, 97437
    • Hautarztpraxis Haßberge /ID# 213644
  • Heilbad Heiligenstadt, Germany, 37308
    • Gemeinschaftspraxis Dres. Anika Hünermund/Mario Pawlak /ID# 213113
  • Holzminden, Germany, 37603
    • Reinecke, Holzminden, DE /ID# 215081
  • Karlsruhe, Germany, 76133
    • Derma Sana /ID# 214544
  • Krefeld, Germany, 47798
    • Praxis Dres. Bornemann/Reinerth /ID# 213368
  • Kulmbach, Germany, 95326
    • Dres. Jacobs & Kollegen /ID# 213652
  • Löhne, Germany, 32584
    • Hagemeier, Loehne, DE /ID# 214845
  • Lüdenscheid, Germany, 58507
    • Dlugosz-Wolf, Luedenscheid, DE /ID# 222000
  • Magdeburg, Germany, 39120
    • Universitaetsklinikum Magdeburg /ID# 215080
  • Mainz, Germany, 55128
    • Dermatologie Quist-BAG Dres. med. Quist PartG /ID# 214249
  • Mönchengladbach, Germany, 41061
    • ZENTderma /ID# 213959
  • Neuwied, Germany, 56564
    • Duplicate_Praxis Dres. Kloss/Peterburgskiy /ID# 213960
  • Nuremberg, Germany, 90402
    • Praxis Dr. Konstantin Ertner /ID# 213640
  • Schwelm, Germany, 58332
    • Praxis Dr. Fränken /ID# 214546
  • Schwerin, Germany, 19053
    • Praxis Dr. Langhoff /ID# 214253
  • Stuttgart, Germany, 70190
    • Praxis Dres. Ziegler & Partner /ID# 213647
  • Waltershausen, Germany, 99880
    • Barnikol, Waltershausen, DE /ID# 213219
  • Werdau, Germany, 08412
    • Pfennig, Werdau, DE /ID# 213657
  • Wiesbaden, Germany, 65185
    • Moeller, Wiesbaden, DE /ID# 213955
  • Witten, Germany, 58453
    • Hautarztpraxis Dr. med. Matthias Hoffmann /ID# 213444
  • Wolfenbüttel, Germany, 38300
    • Franz, Wolfenbuettel, DE /ID# 215355
  • Überlingen, Germany, 88662
    • Braun, Ueberlingen, DE /ID# 213646
  • Baden-Wurttemberg
    • Langenau, Baden-Wurttemberg, Germany, 89129
      • Hautarztpraxis Langenau /ID# 213651
    • Mannheim, Baden-Wurttemberg, Germany, 68167
      • Universitatsklinikum Mannheim /ID# 214569
  • Bavaria
    • Erlangen, Bavaria, Germany, 91054
      • Universitaetsklinikum Erlangen /ID# 213669
    • Freising, Bavaria, Germany, 85354
      • Kurzen, Freising, DE /ID# 214567
    • Memmingen, Bavaria, Germany, 87700
      • Beldio Research GmbH /ID# 213958
    • Nuremberg, Bavaria, Germany, 90419
      • Voelkel, Nuremberg, DE /ID# 213671
  • Hesse
    • Giessen, Hesse, Germany, 35390
      • Gross/Braeu, Giessen, DE /ID# 213367
  • Lower Saxony
    • Bramsche, Lower Saxony, Germany, 49565
      • Studienzentrum an der Hase GbR Dr. Weyergraf/Dr. Frick/Thomas Heiber /ID# 214466
    • Hanover, Lower Saxony, Germany, 30159
      • Praxis Dres. Kaspari /Schenck /ID# 213649
    • Osnabrück, Lower Saxony, Germany, 49074
      • Breitsprecher, Osnabrueck, DE /ID# 213672
  • North Rhine-Westphalia
    • Bielefeld, North Rhine-Westphalia, Germany, 33647
      • Klinikum Rosenhoehe /ID# 215520
    • Remscheid, North Rhine-Westphalia, Germany, 42897
      • Kramer/Mortazawi, Remscheid /ID# 213477
    • Soest, North Rhine-Westphalia, Germany, 59494
      • Karl, Soest, DE /ID# 214547
  • Rhineland-Palatinate
    • Andernach, Rhineland-Palatinate, Germany, 56626
      • Bell, Andernach, DE /ID# 214545
    • Koblenz, Rhineland-Palatinate, Germany, 56068
      • Grossmann, Koblenz, DE /ID# 214245
    • Mainz, Rhineland-Palatinate, Germany, 55131
      • Universitaetsmedizin Mainz /ID# 222025
    • Neuwied, Rhineland-Palatinate, Germany, 56564
      • Zentrum fur Hautgesundheit /ID# 222001
    • Selters, Rhineland-Palatinate, Germany, 56242
      • CMS3 Company for Medical Study /ID# 213676
  • Saarland
    • Merzig, Saarland, Germany, 66663
      • HMS GmbH Zimmer /ID# 225219
  • Saxony
    • Leipzig, Saxony, Germany, 04209
      • Neubauer, Leipzig, DE /ID# 214548
    • Leipzig, Saxony, Germany, 04289
      • Noack-Wiemers, Leipzig, DE /ID# 213654
  • Saxony-Anhalt
    • Magdeburg, Saxony-Anhalt, Germany, 39104
      • Bruecher, Magdeburg, DE /ID# 213476
    • Magdeburg, Saxony-Anhalt, Germany, 39104
      • Praxis Dr. Raschke /ID# 225213
  • Schleswig-Holstein
    • Kiel, Schleswig-Holstein, Germany, 24105
      • Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 213670
    • Kiel, Schleswig-Holstein, Germany, 24148
      • DermaKiel Allergie und Haut Centrum /ID# 213977
  • Thuringia
    • Jena, Thuringia, Germany, 07747
      • Universitaetsklinikum Jena /ID# 214259
• Hungary
  • Szeged, Hungary, 6720
    • Szegedi Tudomanyegyetem /ID# 212958
  • Baranya
    • Pécs, Baranya, Hungary, 7624
      • Pecsi Tudomanyegyetem Klinikai Kozpont /ID# 212960
  • Hajdú-Bihar
    • Debrecen, Hajdú-Bihar, Hungary, 4032
      • Debreceni Egyetem-Klinikai Kozpont /ID# 212959
  • Vas County
    • Szombathely, Vas County, Hungary, 9700
      • Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz /ID# 212961
• Ireland
  • Cork, Ireland, T12 X23H
    • South Infirmary Victoria University Hospital /ID# 213001
  • Limerick, Ireland, V94 F858
    • University Hospital Limerick /ID# 216997
  • Dublin
    • Tallaght, Dublin, Dublin, Ireland, D24 NR0A
      • Tallaght University Hospital /ID# 212999
• Italy
  • Ancona, Italy, 60020
    • Azienda Ospedaliero Universitaria delle Marche /ID# 218720
  • Bari, Italy, 70124
    • A.O.U. Consorziale Policlinico di Bari /ID# 218558
  • Brescia, Italy, 25123
    • ASST degli Spedali Civili di Brescia /ID# 218717
  • Catania, Italy, 95123
    • AOU Policlinico G. Rodolico - San Marco /ID# 219032
  • Milan, Italy, 20097
    • IRCCS Policlinico San Donato /ID# 222002
  • Milan, Italy, 20161
    • IRCCS Istituto Ortopedico Galeazzi /ID# 218867
  • Padua, Italy, 35128
    • Azienda Ospedale-Universita Padova /ID# 221299
  • Perugia, Italy, 06156
    • Azienda Ospedaliera di Perugia - Ospedale S. Maria della Misericordia /ID# 219033
  • Pisa, Italy, 56126
    • Azienda Ospedaliero Universitaria Pisana /ID# 218555
  • Vicenza, Italy, 36100
    • Azienda ULSS 8 Berica /ID# 218845
  • Catanzaro
    • Germaneto, Catanzaro, Italy, 88100
      • Azienda Ospedaliera Universitaria Mater Domini- Campus Salvatore Venuta /ID# 218902
  • Firenze
    • Florence, Firenze, Italy, 50122
      • Università degli Studi di Firenze /ID# 221383
  • Genova
    • Genoa, Genova, Italy, 16132
      • Ospedale San Martino /ID# 218844
  • L Aquila
    • L’Aquila, L Aquila, Italy, 67100
      • ASL 1 Abruzzo - Ospedale regionale San Salvatore /ID# 218719
  • Latina
    • Terracina, Latina, Italy, 04019
      • Sapienza University of Rome - Polo Pontino /ID# 218557
  • Lombardy
    • Rozzano, Lombardy, Italy, 20089
      • IRCCS Istituto Clinico Humanitas /ID# 218560
  • Napoli
    • Naples, Napoli, Italy, 80131
      • Azienda Ospedaliera Universitaria Federico II /ID# 218808
    • Naples, Napoli, Italy, 80138
      • Azienda Ospedaliera Universitaria Luigi Vanvitelli /ID# 218546
  • Roma
    • Rome, Roma, Italy, 00168
      • Presidio Columbus-Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Un /ID# 218718
    • Rome, Roma, Italy, 00133
      • Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 219031
• Japan
  • Osaka, Japan, 550-0006
    • Nippon Life Saiseikai Public Interest Foundation Nippon Life Hospital /ID# 224743
  • Tokyo, Japan, 105-8461
    • The Jikei University School of Medicine /ID# 213393
  • Tokyo, Japan, 173-8605
    • Teikyo University Hospital /ID# 213362
  • Aichi-ken
    • Nagoya, Aichi-ken, Japan, 457-8510
      • Chukyo Hospital /ID# 213405
    • Nagoya, Aichi-ken, Japan, 467-8602
      • Nagoya City University Hospital /ID# 213363
    • Toyoake-shi, Aichi-ken, Japan, 470-1192
      • Duplicate_Fujita Health University Hospital /ID# 224742
  • Ehime
    • Matsuyama, Ehime, Japan, 790-8524
      • Matsuyama Red Cross Hospital /ID# 224745
  • Fukuoka
    • Fukuoka, Fukuoka, Japan, 814-0180
      • Fukuoka University Hospital /ID# 213395
    • Kurume-shi, Fukuoka, Japan, 830-0011
      • Kurume University Hospital /ID# 215034
  • Hokkaido
    • Asahikawa-shi, Hokkaido, Japan, 078-8510
      • Asahikawa Medical University Hospital /ID# 213409
    • Obihiro-Shi, Hokkaido, Japan, 080-0013
      • Takagi Dermatological Clinic /ID# 213407
    • Sapporo, Hokkaido, Japan, 060-0033
      • JR Sapporo Hospital /ID# 213406
  • Kagawa-ken
    • Takamatsu, Kagawa-ken, Japan, 760-0017
      • Takamatsu Red Cross Hospital /ID# 222875
    • Takamatsu, Kagawa-ken, Japan, 760-0017
      • Takamatsu Red Cross Hospital /ID# 241120
  • Kagoshima-ken
    • Kagoshima, Kagoshima-ken, Japan, 890-0064
      • Imamura General Hospital /ID# 228450
  • Kyoto
    • Kyoto, Kyoto, Japan, 602-8566
      • University Hospital Kyoto Prefectural University of Medicine /ID# 213396
    • Kyoto, Kyoto, Japan, 606-8507
      • Kyoto University Hospital /ID# 213404
  • Mie-ken
    • Tsu, Mie-ken, Japan, 514-8507
      • Mie University Hospital /ID# 213387
  • Nagano
    • Matsumoto-shi, Nagano, Japan, 390-8621
      • Shinshu University Hospital /ID# 213408
  • Okinawa
    • Ginowan-shi, Okinawa, Japan, 901-2725
      • University of the Ryukyus Hospital /ID# 213394
  • Osaka
    • Hirakata-shi, Osaka, Japan, 573-1191
      • Kansai Medical University Hospital /ID# 213388
  • Shizuoka
    • Shizuoka, Shizuoka, Japan, 420-8527
      • Shizuoka General Hospital /ID# 224744
  • Tochigi
    • Shimotsuke-shi, Tochigi, Japan, 329-0498
      • Jichi Medical University Hospital /ID# 213403
  • Tokyo
    • Bunkyo-ku, Tokyo, Japan, 113-8603
      • Nippon Medical School Hospital /ID# 213391
    • Chuo-ku, Tokyo, Japan, 104-8560
      • St. Lukes International Hospital /ID# 213392
    • Shinjuku-ku, Tokyo, Japan, 160-0023
      • Tokyo Medical University Hospital /ID# 217125
    • Shinjuku-ku, Tokyo, Japan, 169-0073
      • Japan Community Health care Organization Tokyo Yamate Medical Center /ID# 213389
• Mexico
  • Toluca, Mexico, 50120
    • Neki Servicios Medicos Profesionales S D Rl de Cv /Id# 216977
  • Estado de Baja California
    • Tijuana, Estado de Baja California, Mexico, 22010
      • Dermatologica Sc /Id# 225449
  • Jalisco
    • Guadalajara, Jalisco, Mexico, 44610
      • Centro Dermatologico Del Country S de Rl de Cv /Id# 225460
    • Guadalajara, Jalisco, Mexico, 44657
      • Grupo Clinico Catei Sociedad Civil /Id# 216978
  • Mexico City
    • Mexico City, Mexico City, Mexico, 03100
      • RM Pharma Specialists S.A de C.V. /ID# 225458
    • Mexico City, Mexico City, Mexico, 06500
      • Consultorio Privado /Id# 225457
    • Mexico City, Mexico City, Mexico, 09260
      • Clinica Los Arcos Iztapalapa /Id# 216982
    • Mexico City, Mexico City, Mexico, 11650
      • Centro Especializado en Diabetes, Obesidad y Prevención Cardiovascular (Cedopec) /ID# 216979
• Netherlands
  • The Hague, Netherlands, 2512 VA
    • Haaglanden Medisch Centrum /ID# 232063
  • Gelderland
    • Nijmegen, Gelderland, Netherlands, 6525 GA
      • Radboud Universitair Medisch Centrum /ID# 213592
  • Limburg
    • Roermond, Limburg, Netherlands, 6043 CV
      • Laurentius Ziekenhuis /ID# 230503
  • Provincie Friesland
    • Leeuwarden, Provincie Friesland, Netherlands, 8934 AD
      • Medisch Centrum Leeuwarden /ID# 215779
• Poland
  • Masovian Voivodeship
    • Warsaw, Masovian Voivodeship, Poland, 02-507
      • Panstwowy Instytut Medyczny MSWiA w Warszawie /ID# 225415
  • Podkarpackie Voivodeship
    • Rzeszów, Podkarpackie Voivodeship, Poland, 35-055
      • KSW nr1 w Rzeszowie /ID# 225444
  • Pomeranian Voivodeship
    • Gdansk, Pomeranian Voivodeship, Poland, 80-462
      • COPERNICUS Podmiot Leczniczy Sp. z o.o. - Szpital sw. Wojciecha Adalberta /ID# 225446
  • Silesian Voivodeship
    • Ożarowice, Silesian Voivodeship, Poland, 42-624
      • Labderm S.C. Beata Bergler-Czop, Barbara Sido-Bergler /Id# 225447
• Romania
  • Bucharest, Romania, 020121
    • Spitalul Clinic Colentina /ID# 214307
  • Bucharest, Romania, 020121
    • Spitalul Clinic Colentina /ID# 224810
  • Bucharest, Romania, 020121
    • Spitalul Clinic Colentina /ID# 224811
  • Iași, Romania, 700111
    • Spitalul Clinic Județean de Urgențe "Sfântul Spiridon" /ID# 214335
• Saudi Arabia
  • Mecca, Saudi Arabia
    • Heraa General Hospital /ID# 217214
  • Riyadh, Saudi Arabia, 12372
    • King Saud University Med City /ID# 219065
  • Riyadh, Saudi Arabia, 12625
    • Security Forces Hospital /ID# 221073
  • Riyadh Region
    • Riyadh, Riyadh Region, Saudi Arabia, 11426
      • King Abdulaziz Medical City- National Guard Hospital /ID# 224354
• Spain
  • Badajoz, Spain, 06080
    • Hospital Universitario de Bajadoz /ID# 225091
  • Granada, Spain, 18014
    • Hospital Universitario Virgen de las Nieves /ID# 225107
  • Huelva, Spain, 21005
    • Hospital Juan Ramon Jimenez /ID# 225105
  • León, Spain, 24071
    • Hospital de Leon /ID# 226559
  • Lugo, Spain, 27003
    • Hospital Universitario Lucus Augusti /ID# 233282
  • Madrid, Spain, 28007
    • Hospital General Universitario Gregorio Maranon /ID# 231664
  • Madrid, Spain, 28034
    • Hospital Universitario Ramon y Cajal /ID# 225093
  • Madrid, Spain, 28041
    • Hospital Universitario 12 de Octubre /ID# 238474
  • Palencia, Spain, 34004
    • Hospital San Telmo /ID# 233283
  • Salamanca, Spain, 37711
    • Hospital Universitario de Salamanca /ID# 225078
  • Seville, Spain, 41014
    • Hospital Universitario Virgen de Valme /ID# 225104
  • Zamora, Spain, 49022
    • Hospital Virgen de la Concha /ID# 233285
  • Zaragoza, Spain, 50009
    • Hospital Clinico Universitario Lozano Blesa /ID# 231663
  • Zaragoza, Spain, 50009
    • Hospital Universitario Miguel Servet /ID# 225080
  • Zaragoza, Spain, 50015
    • Hospital Royo Villanova /ID# 231665
  • A Coruna
    • Santiago de Compostela, A Coruna, Spain, 15706
      • Complejo Hospitalario Universitario de Santiago (CHUS) /ID# 225076
  • Balearic Islands
    • Manacor, Balearic Islands, Spain, 07500
      • Hospital de Manacor /ID# 225083
    • Palma de Mallorca, Balearic Islands, Spain, 07120
      • Hospital Universitari Son Espases /ID# 233286
  • Cadiz
    • Puerto Real, Cadiz, Spain, 11510
      • Hospital Universitario de Puerto Real /ID# 225103
  • Madrid
    • Alcalá de Henares, Madrid, Spain, 28805
      • Hospital Universitario Principe de Asturias /ID# 225085
    • Arganda, Madrid, Spain, 28500
      • Hospital Universitario del Sureste /ID# 226561
    • Getafe, Madrid, Spain, 28905
      • Hospital Universitario de Getafe /ID# 225086
    • Leganés, Madrid, Spain, 28911
      • Hospital Universitario Severo Ochoa /ID# 225087
    • Majadahonda, Madrid, Spain, 28222
      • Hospital Universitario Puerta de Hierro - Majadahonda /ID# 225084
    • Móstoles, Madrid, Spain, 28935
      • Hospital General de Mostoles /ID# 225088
  • Murcia
    • Cartagena, Murcia, Spain, 30203
      • Hospital Santa María del Rosell /ID# 225100
  • Pontevedra
    • Vigo, Pontevedra, Spain, 36213
      • Hospital Alvaro Cunqueiro CHUVI /ID# 225077
• Switzerland
  • Bern, Switzerland, 3010
    • Inselspital, Universitaetsspital Bern /ID# 212741
  • Canton of Basel-City
    • Basel Town, Canton of Basel-City, Switzerland, 4031
      • University Hospital Basel /ID# 212744
  • Canton of Nidwalden
    • Obbürgen, Canton of Nidwalden, Switzerland, 6363
      • Waldhotel Health & Medical Excellence /Id# 212743
  • Canton of Zurich
    • Uster, Canton of Zurich, Switzerland, 8610
      • Haut. Venen. Allergie. Zentrum Brunnehof /ID# 212742
    • Zurich, Canton of Zurich, Switzerland, 8091
      • University Hospital Zurich /ID# 216539
• United Arab Emirates
  • Abu Dhabi, United Arab Emirates
    • Mediclinic Khalifa Branch /ID# 217871
  • Abu Dhabi, United Arab Emirates
    • New Medical Center Hospital /ID# 223681
  • Abu Dhabi, United Arab Emirates
    • Skmc /Id# 217873
  • Abu Dhabi, United Arab Emirates
    • Tawam Hospital /ID# 217872
  • Dubai, United Arab Emirates
    • Mediclinic Welcare Hospital /ID# 223683
• United Kingdom
  • Belfast, United Kingdom, BT16 1RH
    • Ulster Hospital - South Eastern Health & Social Care Trust /ID# 215477
  • Dudley, United Kingdom, DY1 2HQ
    • The Dudley Group NHS Foundation Trust /ID# 215839
  • Lyndon, United Kingdom, B71 4HJ
    • Sandwell and West Birmingham Hospitals NHS Trust /ID# 249294
  • Manchester, United Kingdom, M8 5RB
    • Northern Care Alliance NHS Group /ID# 218589
  • Newcastle upon Tyne, United Kingdom, NE3 3HD
    • The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 215479
  • Cambridgeshire
    • Cambridge, Cambridgeshire, United Kingdom, CB2 2QQ
      • Addenbrookes Hospital /ID# 215972
  • Edinburgh, City of
    • Edinburgh, Edinburgh, City of, United Kingdom, EH4 2XU
      • Western General Hospital - NHS Lothian /ID# 249287
  • England
    • London, England, United Kingdom, W12 0HS
      • Hammersmith Hospital /ID# 215978
  • Norfolk
    • Kings Lynn, Norfolk, United Kingdom, PE30 4ET
      • The Queen Elizabeth Hospital, Kings Lynn NHS Foundation Trust /ID# 215476
  • North Yorkshire
    • York, North Yorkshire, United Kingdom, YO31 8HE
      • York Hospital /ID# 227940
  • Northamptonshire
    • Northampton, Northamptonshire, United Kingdom, NN1 5BD
      • Northampton General Hospital NHS Trust /ID# 249297
  • Suffolk
    • Bury St Edmunds, Suffolk, United Kingdom, IP33 2QZ
      • West Suffolk Hospital /ID# 249283
  • Surrey
    • Camberley, Surrey, United Kingdom, GU16 7UJ
      • Frimley Health NHS Foundation Trust /ID# 215976
    • Kingston upon Thames, Surrey, United Kingdom, KT2 7QB
      • Kingston Hospital NHS Foundation Trust /ID# 215973
    • Kingston upon Thames, Surrey, United Kingdom, KT2 7QB
      • Kingston Hospital NHS Foundation Trust /ID# 230856
  • Wales
    • Bridgend, Wales, United Kingdom, CF31 1RQ
      • Cwm Taf Morgannwg University Health Board /ID# 215974

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 14 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

This study will enroll adult subjects with moderate to severe plaque psoriasis.

Description

Inclusion Criteria:

• Confirmed diagnosis of moderate to severe chronic plaque-type psoriasis diagnosed by a specialist and presence of moderate to severe psoriasis symptoms according to physician's judgement at time of recruitment.
• Participant starting any approved treatment for psoriasis and physician's decision must be reached prior to recruitment in the study.
• Participant willing to continue with study documentation after cessation of therapy.

Exclusion Criteria:

• Unwillingness or inability to comply with study requirements.
• Participation in an interventional clinical trial, concurrently or within the last 30 days. Participation in a post-market observational study (PMOS) or Registry is acceptable.

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Participants treated with Risankizumab; Treatment decision independently made of study enrollment
Participants treated with other approved biological therapies; Treatment decision independently made of study enrollment

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Percentage of participants who achieved Psoriasis Area and Severity Index (PASI) 90	PASI is a composite score based on the degree of effect on body surface area of psoriasis and the extension of erythema (reddening), induration (plaque thickness), desquamation (scaling) of the lesions and area affected as observed on the day of examination.	From Month 4 to 3 years
Time to first treatment change	Identify time to first treatment change including discontinuation, dose escalation and dosing interval shortening	From Week 0 (Baseline) to first treatment change

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to first treatment change rate	Time to first treatment change including discontinuation, dose escalation and dose interval shortening.	At 1 year, 2 year, and 3 year
Percentage of participants who achieved Static Physicians Global Assessment (sPGA) 0/1 or sPGA 0	The sPGA is the physician's current assessment of the average thickness, erythema, and scaling of all psoriatic lesions. sPGA scores demonstrate overall psoriatic disease with a lower score indicating less body coverage. The assessment is considered "static" which refers to the patients disease state at the time of the assessments, without comparison to any of the patient's previous disease states, whether at Baseline or at a previous visit.	Monthly for up to 3 years
Percentage of participants who achieved Psoriasis Area and Severity Index (PASI) 75, 90, or 100	PASI is a composite score based on the degree of effect on body surface area of psoriasis and the extension of erythema (reddening), induration (plaque thickness), desquamation (scaling) of the lesions and area affected as observed on the day of examination. Each threshold will be analyzed separately.	Monthly for up to 3 years
Percentage of participants who achieved Absolute PASI<=5, <=3 or <=1	Used to assess the benefit of psoriasis therapy. Each threshold will be analyzed separately.	Monthly for up to 3 years
Time to achieve sPGA 0/1 or sPGA 0	The sPGA is the assessment by the Investigator of the overall disease severity at the time of evaluation. The National Psoriasis Foundation Psoriasis Score version of a static PGA is calculated by averaging the total body erythema, induration, and desquamation scores.	Up to 3 years
Time to achieve PASI 75, 90,or 100	PASI 75, 90, or 100 defined as at least a 75%/ 90%/ 100% reduction in PASI relative to Week 0 (Baseline). Each threshold will be analyzed separately.	Up to 3 years
Percentage of participants who achieve sPGA 0/1 or sPGA 0 at 4 Months and maintained the response status at 1 Year, 2 Years and 3 Years without increasing the dose or shortening the dose interval	Percentage of participants who achieve sPGA 0/1 or sPGA 0 at 4 Months and maintained the response status at 1 Year, 2 Years and 3 Years without increasing the dose or shortening the dose interval.	At 4 months to 1 year, 2 years, and 3 years
Percentage of participants who achieved PASI 90 or PASI 100 at 4 Months and maintained the response status at 1 Year, 2 Years, and 3 Years without changing the indicated dose or dosing interval	Percentage of participants who achieved PASI 90 or PASI 100 demonstrating a 90 or 100% reduction in PASI at 4 Months and maintained the response status at 1 Year, 2 Years, and 3 Years without changing the indicated dose or dosing interval.	At 4 months and 1 year, 2 years, and 3 years
Change in PASI	PASI is a composite score based on the degree of effect on body surface area of psoriasis and the extension of erythema (reddening), induration (plaque thickness), desquamation (scaling) of the lesions and area affected as observed on the day of examination.	From Week 0 to up to 3 years
Change in Body Surface Area (BSA)	BSA can be used to quantify the severity of psoriasis. A decrease in BSA affected by psoriasis indicates improvement.	From Week 0 to up to 3 years
Change in Dermatology Quality of Life Index (DLQI) Score	The Dermatology Life Quality Index (DLQI) is the most commonly used quality of life (QoL) assessment tool. The DLQI is a self-administered, ten-question questionnaire used to assess the effect of different skin diseases on a subject's quality of life, overall health, and disability status. Scores range from 0 (not relevant/not at all) to 3 (very much).	From Week 0 to up to 3 years
Percentage of participants who achieve DLQI 0/1	The Dermatology Life Quality Index (DLQI) is the most commonly used quality of life (QoL) assessment tool. The DLQI is a self-administered, ten-question questionnaire used to assess the effect of different skin diseases on a subject's quality of life, overall health, and disability status. The higher the DLQI score, the more quality of life is impaired.	Monthly for up to 3 years
Change in Treatment Satisfaction Questionnaire for Medication (TSQM) score	The Treatment Satisfaction Questionnaire for Medication (TSQM) is a widely used generic measure to assess treatment satisfaction with their medication. This is a 100-point scale with higher scores indicating greater satisfaction with medication and provides scores on four scales - side effects, effectiveness, convenience and global satisfaction.	From Week 0 to up to 3 years

Collaborators and Investigators

• Sponsor: AbbVie
• Investigators: Study Director: ABBVIE INC., AbbVie

Publications and helpful links

General Publications

• Thaci D, Ohtsuki M, Maul JT, Szegedi A, Luna PC, Lynde CW, Soliman AM, Wang H, Kaufmann C, Ashley DG, Madihlaba T, Rubant S, Papp KA. Real-World Effectiveness of Risankizumab in Patients with Moderate-to-Severe Psoriasis: Interim Analysis from the VALUE Global Prospective Post-marketing Observational Study at 25 Months. Dermatol Ther (Heidelb). 2025 Feb;15(2):381-394. doi: 10.1007/s13555-025-01342-0. Epub 2025 Feb 4.

Helpful Links

• Related info

Study record dates

Study Major Dates

• Study Start (Actual): July 1, 2019
• Primary Completion (Actual): September 2, 2025
• Study Completion (Actual): September 2, 2025

Study Registration Dates

• First Submitted: June 10, 2019
• First Submitted That Met QC Criteria: June 10, 2019
• First Posted (Actual): June 11, 2019

Study Record Updates

• Last Update Posted (Estimated): November 17, 2025
• Last Update Submitted That Met QC Criteria: November 14, 2025
• Last Verified: November 1, 2025

More Information

Terms related to this study

• Keywords: Chronic Plaque Psoriasis Risankizumab Biologics Psoriasis Vulgaris
• Additional Relevant MeSH Terms: Skin Diseases; Skin Diseases, Papulosquamous; Psoriasis
• Other Study ID Numbers: P19-377

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No