Multicenter Normal Reference Study of Tissue Motion Tracking of Mitral Annular Displacement(TMAD) (TMAD)

May 19, 2020 updated by: Weidong Ren

The Multi-center Normal Reference Study of Tissue Motion Tracking of Mitral Annular Displacement(TMAD) in Chinese Han Adults Study

To establish the range of TMADmid、TMADmidpt% by using tissue motion tracking of mitral annular displacement (TMAD), and to explore the influencing factors.

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Detailed Description

With the gradual aging of Chinese population and continuous development of economy and society, the incidence of cardiovascular disease and the number of patients have increased rapidly. The National Heart Center has reported that the number of patients with clinically diagnosed cardiovascular disease in China has reached 290 million in 2016 (240 million in 2014). Cardiovascular disease is the most common cause of death in humans. Left ventricular systolic function plays an important role in the treatment and prognosis of patients with myocardial diseases. Early sensitive detection of left ventricular systolic function, timely treatment and early evaluation of the therapeutic effect can greatly reduce the death of patients with myocardial diseases rate.

At present, the left ventricular ejection fraction (LVEF), measured by the two-plane Simpson method in clinical, is one of the methods to evaluating left ventricular systolic function. It is especially suitable for patients with geometric deformation of the left ventricle, but some early heart failure patients' LVEF is still in the normal range, whose systolic function has been reduced, but. In recent years, 2D longitudinal strain is one of the indicators for evaluating left ventricular systolic function. The researchers believe that 70% of cardiac function is obtained by longitudinal movement of myocardium , which can be used as a good indicator for identifying myocardial diseases. However, both the two-plane Simpson method and the 2D longitudinal strain require good sound transmission conditions and good image quality. You can clearly see the endocardium and epicardium. Not all of patients in the clinic can get better image.

Basic and clinical studies and clinical statistics show that tissue motion tracking of mitral annular displacement (TMAD) is not affected by image quality and can effectively evaluate left ventricular systolic function. It can measure the mitral valve annulus displacement by marking the mitral valve annulus point and the reference point, which can quickly and accurately evaluate the left ventricular longitudinal contraction function.

Study Type

Observational

Enrollment (Anticipated)

2400

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Anhui
      • Hefei, Anhui, China
        • Recruiting
        • Anhui Provincial Hospital
        • Contact:
          • Haoyi Yang
          • Phone Number: 13720360838
        • Principal Investigator:
          • Haoyi Yang
    • Chongqing
      • Chongqing, Chongqing, China
        • Recruiting
        • Chongqing University Cancer Hospital
        • Contact:
          • Fang Li
          • Phone Number: 13808312288
        • Principal Investigator:
          • Fang Li
    • Gansu
      • Baiyin, Gansu, China
        • Recruiting
        • Gansu Baiyin Second People's Hospital
        • Contact:
          • Xinjian Yang
          • Phone Number: 13619308289
        • Principal Investigator:
          • Xinjian Yang
    • Guangdong
      • Foshan, Guangdong, China
        • Recruiting
        • The First People's Hospital of Foshan City
        • Contact:
          • Yuqiong Lai
          • Phone Number: 13809859038
        • Principal Investigator:
          • Yuqiong Lai
      • Gaozhou, Guangdong, China
        • Recruiting
        • The People's Hospital of Gaozhou
        • Contact:
          • Guoxiong Wei
          • Phone Number: 13580011299
        • Principal Investigator:
          • Guoxiong Wei
      • Guangzhou, Guangdong, China
        • Recruiting
        • The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
        • Contact:
          • Pengtao Sun
          • Phone Number: 18620168536
        • Principal Investigator:
          • Pengtao Sun
      • Qingyuan, Guangdong, China
        • Recruiting
        • Qingyuan People's Hospital
        • Contact:
          • Liwen Wu
          • Phone Number: 13802896000
        • Principal Investigator:
          • Liwen Wu
    • Guangxi
      • Baise, Guangxi, China
        • Recruiting
        • Affiliated Hospital of Youjiang Medical University for Nationalities
        • Contact:
          • Chengcai Chen
          • Phone Number: 13977617591
        • Principal Investigator:
          • Chengcai Chen
      • Baise, Guangxi, China
        • Recruiting
        • People's Hospital of Baise
        • Contact:
          • Maoyi Li
          • Phone Number: 18677628852
        • Principal Investigator:
          • Maoyi Li
      • Chongzuo, Guangxi, China
        • Recruiting
        • The People'S Hospital of Chong Zuo
        • Contact:
          • Mei Li
          • Phone Number: 13807873360
        • Principal Investigator:
          • Mei Li
      • Guigang, Guangxi, China
        • Recruiting
        • Guigang City People's Hospital
        • Contact:
          • Zongxin Tao
          • Phone Number: 13737559953
        • Principal Investigator:
          • Zongxin Tao
      • Laibin, Guangxi, China
        • Recruiting
        • Laibin People's Hospital
        • Contact:
          • Xianling Mo
          • Phone Number: 18907828711
        • Principal Investigator:
          • Xianling Mo
      • Nanning, Guangxi, China
        • Recruiting
        • Guangxi International Zhuang Medical Hospital
        • Contact:
          • Minhua Chen
          • Phone Number: 13517689974
        • Principal Investigator:
          • Minhua Chen
      • Nanning, Guangxi, China
        • Recruiting
        • Guangxi Minzu Hospital
        • Contact:
          • Haiqing Su
          • Phone Number: 13978827211
        • Principal Investigator:
          • Haiqing Su
      • Yulin, Guangxi, China
        • Recruiting
        • The first peopel's hospital of yulin
        • Contact:
          • Hongxia Yin
          • Phone Number: 18977585936
        • Principal Investigator:
          • Hongxia Yin
    • Hainan
      • Haikou, Hainan, China
        • Recruiting
        • The First Affiliated Hospital of Hainan Medical University
        • Contact:
          • Ruixia Nan
          • Phone Number: 13036006449
        • Principal Investigator:
          • Ruixia Nan
    • Hebei
      • Chengde, Hebei, China
        • Recruiting
        • Fengning Manchu Autonomous County Hospital
        • Contact:
          • Dongsheng Zhao
          • Phone Number: 13483872058
        • Principal Investigator:
          • Dongsheng Zhao
      • Handan, Hebei, China
        • Recruiting
        • Handan First Hospital
        • Contact:
          • Shaobo Wang
          • Phone Number: 15631006699
        • Principal Investigator:
          • Shaobo Wang
      • Shijiazhuang, Hebei, China
        • Recruiting
        • shijiazhuang No.1 Hospital
        • Contact:
          • Xiaoqing Yang
          • Phone Number: 17603119685
        • Principal Investigator:
          • Xiaoqing Yang
      • Shijiazhuang, Hebei, China
        • Recruiting
        • The Fourth Hospital of Heibei Medical University Hebei Cancer Hospital
        • Contact:
          • Xiaohong Gong
          • Phone Number: 13831110712
        • Principal Investigator:
          • Xiaohong Gong
      • Tangshan, Hebei, China
        • Recruiting
        • Tangshan Fengnan District Hospital
        • Contact:
          • Yihong Li
          • Phone Number: 19931565611
        • Principal Investigator:
          • Yihong Li
      • Xingtai, Hebei, China
        • Recruiting
        • Xingtai Third Hospital
        • Contact:
          • Hongbing Peng
          • Phone Number: 13131991001
        • Principal Investigator:
          • Hongbing Peng
    • Heilongjiang
      • Mudanjiang, Heilongjiang, China
        • Recruiting
        • Mudanjiang Cardiovascular Hospital
        • Contact:
          • Guangyu Gao
          • Phone Number: 13704838773
        • Principal Investigator:
          • Guangyu Gao
      • Qiqihar, Heilongjiang, China
        • Recruiting
        • The Third Affiliated Hospital of Qiqihar Medical Hospital
        • Contact:
          • Xiao Liang
          • Phone Number: 13846283727
        • Principal Investigator:
          • Xiao Liang
    • Henan
      • Nanyang, Henan, China
        • Recruiting
        • Nanyang Second People's Hospital
        • Contact:
          • Xu meng Ding
          • Phone Number: 13503779799
        • Principal Investigator:
          • Xu meng Ding
    • Hunan
      • Changsha, Hunan, China
        • Recruiting
        • People's Hospital of Hunan Province
        • Contact:
          • Kun Ao
          • Phone Number: 13467511183
        • Principal Investigator:
          • Kun Ao
      • Huaihua, Hunan, China
        • Recruiting
        • The First People's Hospital of Huaihua
        • Contact:
          • Rui Zhang
          • Phone Number: 13973099796
        • Principal Investigator:
          • Rui Zhang
    • Inner Mongolia
      • Baotou, Inner Mongolia, China
        • Recruiting
        • The First Affiliated Hospital of Baotou Medical College
        • Contact:
          • Guozhen Yan
          • Phone Number: 18547218068
        • Principal Investigator:
          • Guozhen Yan
      • Hohhot, Inner Mongolia, China
        • Recruiting
        • The Affiliated Hospital of Inner Mongolia Medical University
        • Contact:
          • Xiaoshan Zhang
          • Phone Number: 13947133133
        • Principal Investigator:
          • Xiaoshan Zhang
    • Jiangxi
      • Jiujiang, Jiangxi, China
        • Recruiting
        • Jiujiang University Affiliated Hospital
        • Contact:
          • Xuehua Xiao
          • Phone Number: 13517920820
        • Principal Investigator:
          • Xuehua Xiao
    • Jilin
      • Baicheng, Jilin, China
        • Recruiting
        • Baicheng Central Hospital
        • Contact:
          • Fan Zhang
          • Phone Number: 13943623116
        • Principal Investigator:
          • Fan Zhang
      • Jilin, Jilin, China
        • Recruiting
        • Jilin Central General Hospital
        • Contact:
          • Bing Gong
          • Phone Number: 15543430477
        • Principal Investigator:
          • Bing Gong
    • Liaoning
      • Benxi, Liaoning, China
        • Recruiting
        • Benxi Central Hospital
        • Contact:
          • Xingbin Wang
          • Phone Number: 18941435757
        • Principal Investigator:
          • Xingbin Wang
      • Chaoyang, Liaoning, China
        • Recruiting
        • Chaoyang Central Hospital
        • Contact:
          • Suli Zhang
          • Phone Number: 18040159891
        • Principal Investigator:
          • Suli Zhang
      • Dalian, Liaoning, China, 116011
        • Recruiting
        • The First Affiliated Hospital of Dalian Medical University
        • Contact:
          • Tao Cong
          • Phone Number: 18098875836
        • Principal Investigator:
          • Tao Cong
      • Dalian, Liaoning, China, 116033
        • Recruiting
        • Dalian Municipal Central Hospital
        • Contact:
          • Xiaofang Pan
          • Phone Number: 13591327871
        • Principal Investigator:
          • Xiaofang Pan
      • Dalian, Liaoning, China
        • Recruiting
        • The Second Affiliated Hospital of Dalian Medical University
        • Contact:
          • Jun Wu
          • Phone Number: 13942022794
        • Principal Investigator:
          • Jun Wu
      • Dandong, Liaoning, China
        • Recruiting
        • Dandong Central Hospital
        • Contact:
          • Xin Jin
          • Phone Number: 13842580705
        • Principal Investigator:
          • Xin Jin
      • Fushun, Liaoning, China
        • Recruiting
        • Fuchun Central Hospital
        • Contact:
          • Chen Zhang
          • Phone Number: 13941314545
        • Principal Investigator:
          • Chen Zhang
      • Fushun, Liaoning, China
        • Recruiting
        • General Hospital of Fushun Mining Bureau
        • Contact:
          • Chunfeng Wang
          • Phone Number: 15694239647
        • Principal Investigator:
          • Chunfeng Wang
      • Jinzhou, Liaoning, China
        • Recruiting
        • The First Affiliated Hospital of Jinzhou Medical University
        • Contact:
          • Yuhong Li
          • Phone Number: 13940637604
        • Principal Investigator:
          • Yuhong Li
      • Shenyang, Liaoning, China
        • Recruiting
        • The First Hospital of China Medical University
        • Principal Investigator:
          • jun Yang
        • Contact:
          • Jun Yang
          • Phone Number: 13840266962
      • Shenyang, Liaoning, China, 110004
        • Recruiting
        • Shengjing Hospital Of China Medical University
        • Contact:
        • Principal Investigator:
          • Lu Sun
      • Shenyang, Liaoning, China
        • Recruiting
        • Central Hospital Affiliated to Shenyang Medical College
        • Contact:
          • Tong Zang
          • Phone Number: 18002477367
        • Principal Investigator:
          • Tong Zang
      • Shenyang, Liaoning, China
        • Recruiting
        • The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
        • Contact:
          • Linwei Hong
          • Phone Number: 18040041999
        • Principal Investigator:
          • Linwei Hong
      • Shenyang, Liaoning, China
        • Recruiting
        • The People's Hospital of Liaoning Province
        • Contact:
          • Fang Zhu
          • Phone Number: 17702485777
      • Shenyang, Liaoning, China
        • Recruiting
        • The Second Affiliated Hospital of Shenyang Medical College
        • Contact:
          • Jie Liu
          • Phone Number: 18002452866
        • Principal Investigator:
          • Jie Liu
    • Ningxia
      • Yinchuan, Ningxia, China
        • Recruiting
        • General Hospital of Ningxia Medical University
        • Contact:
          • Lisha Na
          • Phone Number: 13995376025
        • Principal Investigator:
          • Lisha Na
    • Qinghai
      • Xining, Qinghai, China
        • Recruiting
        • Qinghai Provincial People's Hospital
        • Contact:
          • Haixia Sun
          • Phone Number: 18597015698
        • Principal Investigator:
          • Haixia Sun
    • Shandong
      • Jinan, Shandong, China
        • Recruiting
        • The Second Hospital of Shandong University
        • Contact:
          • Yongmei Wang
          • Phone Number: 15153169591
        • Principal Investigator:
          • Yongmei Wang
      • Liaocheng, Shandong, China
        • Recruiting
        • Liaocheng People's Hospital
        • Contact:
          • Yilin Liu
          • Phone Number: 13346251883
        • Principal Investigator:
          • Yilin Liu
      • Yantai, Shandong, China
        • Recruiting
        • Yantai Affiliated Hospital of Binzhou Medical University
        • Contact:
          • Jiange Li
          • Phone Number: 18363805900
        • Principal Investigator:
          • Jiange Li
      • Zibo, Shandong, China
        • Recruiting
        • Zibo City Linzi District People's Hospital
        • Contact:
          • Ying Liu
          • Phone Number: 17660292589
    • Shanghai
      • Shanghai, Shanghai, China
        • Recruiting
        • Shanghai Pudong New District Zhoupu Hospital
        • Contact:
          • Ye Song
          • Phone Number: 13818086439
        • Principal Investigator:
          • Ye Song
    • Shanxi
      • Baoji, Shanxi, China
        • Recruiting
        • Baoji Central Hospital
        • Contact:
          • Guoliang Dun
          • Phone Number: 13509176168
        • Principal Investigator:
          • Guoliang Dun
      • Hanzhong, Shanxi, China
        • Recruiting
        • Hanzhong Central Hospital
        • Contact:
          • Zipeng Liu
          • Phone Number: 13084899536
        • Principal Investigator:
          • Zipeng Liu
      • Xi'an, Shanxi, China
        • Recruiting
        • The Second Affiliated Hospital of Xi'an Jiaotong University
        • Principal Investigator:
          • Qi Zhou
        • Contact:
          • Qi Zhou
          • Phone Number: 18966896600
      • Xi'an, Shanxi, China
        • Recruiting
        • The First Affiliated Hospital of Xi'an Jiaotong University
        • Contact:
          • Shun Wang
          • Phone Number: 18991232635
        • Principal Investigator:
          • Shun Wang
      • Xi'an, Shanxi, China
        • Recruiting
        • Shaanxi Provincial People's Hospital
        • Contact:
          • Xiangping Guan
          • Phone Number: 13991979638
        • Principal Investigator:
          • Xiangping Guan
      • Xianyang, Shanxi, China
        • Recruiting
        • Xianyang Central Hospital
        • Contact:
          • Lei Cui
          • Phone Number: 13809141343
        • Principal Investigator:
          • Lei Cui
    • Sichuan
      • Chendu, Sichuan, China
        • Recruiting
        • The Peoplep'S Hospital of Wenjiang District,Chengdu
        • Contact:
          • Jing Tan
          • Phone Number: 13708204839
        • Principal Investigator:
          • Jing Tan
      • Chengdu, Sichuan, China
        • Recruiting
        • Affiliated Hospital of Chengdu University of Traditional Chinese Medicine
        • Contact:
          • Yu Kang
        • Principal Investigator:
          • Yu Kang
      • Chengdu, Sichuan, China
        • Recruiting
        • Chengdu First People's Hospital
        • Contact:
          • Xinyun Chen
          • Phone Number: 18011390127
        • Principal Investigator:
          • Xinyun Chen
      • Chengdu, Sichuan, China
        • Recruiting
        • Chengdu Second People's Hospital
        • Contact:
          • Yun Shi
          • Phone Number: 13658051337
        • Principal Investigator:
          • Yun Shi
      • Chengdu, Sichuan, China
        • Recruiting
        • Chengdu Third People's Hospital
        • Contact:
          • Feng Xiong
        • Principal Investigator:
          • Feng Xiong
      • Guang'an, Sichuan, China
        • Recruiting
        • West China-Guang'An Hospital,Sichuan University
        • Contact:
          • Shuwen Chen
          • Phone Number: 13550980666
        • Principal Investigator:
          • Shuwen Chen
      • Leshan, Sichuan, China
        • Recruiting
        • The people's hospital of Leshan
        • Contact:
          • Ying Liu
          • Phone Number: 17628182552
      • Luzhou, Sichuan, China
        • Recruiting
        • The affiliated hospital of Southwest Medical University
        • Contact:
          • Jizhu Xia
          • Phone Number: 18715770806
        • Principal Investigator:
          • Jizhu Xia
      • Nanchong, Sichuan, China
        • Recruiting
        • Affiliated Hospital of North Sichuan Medical College
        • Contact:
          • Wensheng Yue
          • Phone Number: 13690767960
        • Principal Investigator:
          • Wensheng Yue
      • Nanchong, Sichuan, China
        • Recruiting
        • Nanchong Central Hospital
        • Contact:
          • Xuebin Liu
          • Phone Number: 15882613551
        • Principal Investigator:
          • Xuebin Liu
      • Panzhihua, Sichuan, China
        • Recruiting
        • Panzhihua Central Hospital
        • Contact:
          • Xiaoli Wu
          • Phone Number: 13982323405
        • Principal Investigator:
          • Xiaoli Wu
      • Suining, Sichuan, China
        • Recruiting
        • Suining Central Hospital
        • Contact:
          • Xiaoyong Luo
          • Phone Number: 18008258086
        • Principal Investigator:
          • Xiaoyong Luo
    • Xinjiang
      • Shihezi, Xinjiang, China
        • Recruiting
        • First Affiliated Hospital,School of Medical,Shihezi University
        • Contact:
          • Guilin Lu
          • Phone Number: 13899527866
        • Principal Investigator:
          • Guilin Lu
      • Urumqi, Xinjiang, China
        • Recruiting
        • Urumqi Friendship Hospital
        • Contact:
          • Baoling Wang
          • Phone Number: 13579235938
        • Principal Investigator:
          • Baoling Wang
    • Yunnan
      • Dali, Yunnan, China
        • Recruiting
        • Dali Bai Autonomous Prefecture People's Hospital
        • Contact:
          • Yan Cui
          • Phone Number: 13987275528
        • Principal Investigator:
          • Yan Cui

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

14 years to 75 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

2400 healthy adults with normal physical examination items will be selected from the physical examination center. According to sex and age stratification, totally 2400 cases will contain 1200 males and 1200 females. From 18 to 79 years old, they will be divided into 6 groups: 18-29 years, 30-39 years, 40-49 years, 50-59 years, 60-69 years and 70-79 years (n=400 per group).

Description

Inclusion Criteria:

  1. Han nationality
  2. Ages 18-79.
  3. Normal body mass index (18-25kg / m2).
  4. Normal blood pressure (139-90 / 89-60mmHg).
  5. No history of cardiovascular and respiratory diseases.
  6. No abnormality was found in physical examination of cardiovascular and respiratory system.
  7. Blood glucose, lipid profile and electrocardiogram were normal.
  8. Echocardiography showed no structural heart disease and normal heart function.
  9. No history of medications affecting cardiovascular system.

Exclusion Criteria:

  1. Clinically significant or moderate heart valve regurgitation.
  2. Respiratory diseases: acute or chronic respiratory diseases.
  3. Endocrine diseases: thyroid disease, diabetes, hyperaldosteronism, pheochromocytoma, and abnormal adrenal function.
  4. Anemia.
  5. Pregnant or lactating women.
  6. Abnormal liver function (glutamyl aminotransferase exceeds 2.0 times the upper limit of normal value), abnormal renal function (creatinine exceeds the normal value), increased blood lipids (triglycerides, total cholesterol, low density and high density lipoprotein, any of which is higher than Normal value).
  7. Connective tissue disease.
  8. Tumor.
  9. Aortic and peripheral vascular diseases: aortic dilatation, aortic dissection, aortic constriction, multiple arteritis, and atherosclerosis.
  10. Drink more than 50ml of white wine daily; more than 100ml of red wine; more than 300ml of beer.
  11. Professional athletes.
  12. The poor quality of the ultrasound image cannot satisfy the parameter measurement and analysis.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Control
  • Time Perspectives: Prospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
18-29 year-old group
Based on the inclusion crtiteria, 200 healthy Han people at aged 18-29 and both sexes will be recruited in the analysis. Normal reference values of tissue motion tracking of mitral annular displacement will be obtained.
Radiation: Echocardiography
left ventricular systolic function of all participants were measured by tissue motion tracking of mitral annular displacement using PHILIPS
30-39 year-old group
Based on the inclusion crtiteria, 200 healthy Han people at aged 30-39 and both sexes will be recruited in the analysis. Normal reference values of tissue motion tracking of mitral annular displacement will be obtained.
Radiation: Echocardiography
left ventricular systolic function of all participants were measured by tissue motion tracking of mitral annular displacement using PHILIPS
40-49 year-old group
Based on the inclusion crtiteria, 200 healthy Han people at aged 40-49 and both sexes will be recruited in the analysis. Normal reference values of tissue motion tracking of mitral annular displacement will be obtained.
Radiation: Echocardiography
left ventricular systolic function of all participants were measured by tissue motion tracking of mitral annular displacement using PHILIPS
50-59 year-old group
Based on the inclusion crtiteria, 200 healthy Han people at aged 50-59 and both sexes will be recruited in the analysis. Normal reference values of tissue motion tracking of mitral annular displacement will be obtained.
Radiation: Echocardiography
left ventricular systolic function of all participants were measured by tissue motion tracking of mitral annular displacement using PHILIPS
60-69 year-old group
Based on the inclusion crtiteria, 200 healthy Han people at aged 60-69 and both sexes will be recruited in the analysis. Normal reference values of tissue motion tracking of mitral annular displacement will be obtained.
Radiation: Echocardiography
left ventricular systolic function of all participants were measured by tissue motion tracking of mitral annular displacement using PHILIPS
70-79 year-old group
Based on the inclusion crtiteria, 200 healthy Han people at aged 70-79 and both sexes will be recruited in the analysis. Normal reference values of tissue motion tracking of mitral annular displacement will be obtained.
Radiation: Echocardiography
left ventricular systolic function of all participants were measured by tissue motion tracking of mitral annular displacement using PHILIPS

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
left ventricular systolic function was measured by tissue motion tracking of mitral annular displacement（TMAD）
Time Frame: 1 day
To establish the range of TMADmid by using TMAD
1 day
left ventricular systolic function was measured by tissue motion tracking of mitral annular displacement（TMAD）
Time Frame: 1 day
To establish the range of TMADmidpt% by using TMAD
1 day

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
left ventricular systolic function was measured by the two-plane Simpson method
Time Frame: 1 day
the left ventricular ejection fraction measured by the two-plane Simpson method, is the standard of the clinical
1 day

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Serum biochemical index
Time Frame: 1 day
Serum laboratory testing for blood cholesterol level (total cholesterol, HDL (high-density lipoprotein), LDL (low-density lipoproteins), triglycerides), fasting blood-glucose will be examed.
1 day

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Weidong Ren

Investigators

  • Principal Investigator: Weidong Ren, Shengjing Hospital of China Medical Univeristy

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Anticipated)

June 1, 2020

Primary Completion (Anticipated)

June 30, 2021

Study Completion (Anticipated)

September 30, 2021

Study Registration Dates

First Submitted

May 9, 2020

First Submitted That Met QC Criteria

May 19, 2020

First Posted (Actual)

May 22, 2020

Study Record Updates

Last Update Posted (Actual)

May 22, 2020

Last Update Submitted That Met QC Criteria

May 19, 2020

Last Verified

May 1, 2020

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • ShengJing Hospital Ultrasound

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

Undecided

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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