A Worldwide Cancer Registry Enrolling Participants Profiled With a Next-Generation Sequencing Test

A Registry to Collect Characteristics and Outcomes From Patients With Solid Tumors Profiled With a Next-Generation Sequencing Test (WAYFIND-R)

WAYFIND-R is a registry that aims to capture high-quality real-world data linking next-generation sequencing, treatments and outcomes from cancer patients diagnosed with a solid tumour. The WAYFIND-R has three main overarching objectives: 1. To provide a platform to support the design and conduct of clinical and epidemiological research; 2. To develop an evidence-generation platform to better understand health outcomes and cancer care processes; and 3. To characterize the treatments and clinical course of solid tumor cancers in patients who have undergone NGS testing.

Study Overview

• Status: Recruiting
• Conditions: Solid Tumours

• Study Type: Observational
• Enrollment (Estimated): 15000

Contacts and Locations

• Study Contact: Name: Reference Study ID # MX39897 https://forpatients.roche.com/; Phone Number: 888-662-6728; Email: global-roche-genentech-trials@gene.com

Study Locations

• Argentina
  • Buenos Aires, Argentina, C1431FWN
    • Recruiting
    • Cemic; Oncologia Clinica
  • Buenos Aires, Argentina, 1426
    • Recruiting
    • Instituto Alexander Fleming
  • Buenos Aires, Argentina, C1181ACH
    • Withdrawn
    • Hospital Italiano
• Austria
  • Graz, Austria, 8036
    • Recruiting
    • LKH-UNIV. KLINIKUM GRAZ; Klinische Abteilung für Onkologie
• Brazil
  • RS
    • Porto Alegre, RS, Brazil, 90035-000
      • Recruiting
      • Hospital Moinhos de Vento
  • SP
    • Sao Paulo, SP, Brazil, 01246-000
      • Recruiting
      • Instituto do Cancer do Estado de Sao Paulo - ICESP
    • Sao Paulo, SP, Brazil, 01323-903
      • Recruiting
      • Hospital Alemão Oswaldo Cruz
    • Sao Paulo, SP, Brazil, 04062-001
      • Recruiting
      • D'or Instituto de Pesquisa e Educação
    • São Paulo, SP, Brazil, 01321-00
      • Recruiting
      • Beneficencia Portuguesa de Sao Paulo
• Canada
  • Alberta
    • Calgary, Alberta, Canada, T2N 4N2
      • Recruiting
      • Alberta Health services
  • Ontario
    • Ottawa, Ontario, Canada, K1H 8L6
      • Recruiting
      • The Ottawa Hospital - General Campus
• Chile
  • Las Condes, Chile, 7560908
    • Recruiting
    • Centro de Oncología de Precisión
  • Santiago, Chile, 8330074
    • Recruiting
    • Centro de Cancer Pontificie Universidad Catolica de Chile
• Colombia
  • Bogota, Colombia, 11001
    • Withdrawn
    • Clinica del Country
  • Bogota, Colombia
    • Recruiting
    • Fundacion Cardioinfantil
  • Bogota, Colombia
    • Withdrawn
    • Hospital Universitario Mayor Mederi
  • Bogota, D.C., Colombia, 111321
    • Recruiting
    • Organizacion Sanitas Internacional
  • Bogota, D.C., Colombia, 110131
    • Recruiting
    • Fundación CTIC - Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo
  • Cali, Colombia
    • Recruiting
    • Fundacion Clinica Valle del Lili; Unidad de Investigaciones Clinicas
  • Medellin, Colombia, 050024
    • Recruiting
    • Instituto Cancerologia Medellin; Clinica Las Americas
  • Medellin, Colombia, 50010
    • Recruiting
    • Clinica ASTORGA
• Egypt
  • Cairo, Egypt
    • Recruiting
    • International Medical Center; Oncology Department
• Estonia
  • Tallinn, Estonia, 11312
    • Recruiting
    • East Tallinn Central Hospital; Clinic of Internal Medicine
  • Tallinn, Estonia, 13419
    • Recruiting
    • North Estonia Medical Centre Foundation; Oncology Center
  • Tartu, Estonia, 51014
    • Recruiting
    • Tartu Uni Hospital; Surgery Clinic
• France
  • Besancon, France, 25030
    • Recruiting
    • HOPITAL JEAN MINJOZ; Oncologie
  • Brest, France, 29200
    • Recruiting
    • CHU Brest - Hôpital Morvan
  • Caen, France, 14076
    • Recruiting
    • Centre Francois Baclesse; Recherche Clinique
  • Clermont Ferrand, France, 63011
    • Recruiting
    • Centre Jean Perrin; Division De Recherche Clinique
  • Levallois-Perret, France, 92300
    • Recruiting
    • Hôpital Franco-Britannique- Fondation Cognacq-Jay; Cancerologie
  • Lille, France, 59020
    • Recruiting
    • Centre Oscar Lambret
  • Lyon, France, 69373
    • Recruiting
    • Centre Leon Berard; Oncologie Genetique
  • Paris, France, 75005
    • Recruiting
    • Institut Curie
  • Quimper, France, 29107
    • Recruiting
    • CH de Cornouailles
  • Rennes, France, 35000
    • Recruiting
    • Centre Eugène Marquis
  • Saint Etienne, France, 42055
    • Recruiting
    • CHU Saint Etienne - Hopital Nord
  • St Etienne, France, 42100
    • Recruiting
    • Hôpital Privé de la Loire, Ramsay Saint Etienne
  • Toulon, France, 83056
    • Recruiting
    • CHI de Toulon - Hôpital Sainte Musse
  • Villejuif, France, 94805
    • Recruiting
    • Gustave Roussy
• Germany
  • Bad Saarow, Germany, 15526
    • Recruiting
    • HELIOS Klinikum Bad Saarow; Klinik Hämatologie, Onkologie und Palliativmedizin, Sarkomzentrum
  • Halle (Saale), Germany, 06120
    • Recruiting
    • Universitätsklinikum Halle (Saale); Krukenberg- Krebszentrum Halle; onkologisches Zentrum
  • Hannover, Germany, 30625
    • Recruiting
    • Medizinische Hochschule Hannover; Klinik für Gastroenterologie, Hepatologie und Endokrinologie
  • Heilbronn, Germany, 74078
    • Recruiting
    • SLK-Kliniken Heilbronn GmbH; Klinik für Innere Medizin III; Schwerpunkt Häma./Onko./Palliativm.
  • Stuttgart, Germany, 70174
    • Recruiting
    • Katharinenhospital Stuttgart; Klinik für Hämatologie, Onkologie und Palliativmedizin
  • Wesel, Germany, 46483
    • Recruiting
    • Marien-Hospital Wesel; Klinik für Gastro., Onko. + Häma., Diabetologie und Rheumatologie
• Greece
  • Asvestochori, Greece, 570 10
    • Recruiting
    • General Hospital "G.Papanikolaou"; Pulmonogy Clinic
  • Athens, Greece, 115 28
    • Recruiting
    • Alexandras General Hospital of Athens; Oncology Department
  • Athens, Greece, 115 26
    • Recruiting
    • Henri Dunant Hospital; Oncology Dept.
  • Faliro, Greece, 185 47
    • Recruiting
    • Metropolitan Hospital Fourth Oncology Clinic
  • Thessaloniki, Greece, 546 22
    • Recruiting
    • BioClinic Thessaloniki
• India
  • Andhra Pradesh
    • Hyderabad, Andhra Pradesh, India, 500019
      • Withdrawn
      • American Oncology Institute
  • Delhi
    • New Delhi, Delhi, India, 110017
      • Not yet recruiting
      • Max Super Speciality Hospital
  • Karnataka
    • Bangalore, Karnataka, India, 560017
      • Recruiting
      • Manipal Hospital; Department of Oncology
    • Banglore, Karnataka, India, 560027
      • Recruiting
      • HealthCare Global Enterprises Limited; Medical Oncology
  • Maharashtra
    • Mumbai, Maharashtra, India, 400012
      • Recruiting
      • Tata Memorial Hospital; Dept of Medical Oncology
    • Mumbai, Maharashtra, India, 400036
      • Recruiting
      • MOC Cancer Care & Research Centre (Unit of Cellcure Cancer Centre Pvt Ltd)
    • Thane, Maharashtra, India, 401107
      • Recruiting
      • Bhaktivedanta Hospital and Research Institute
  • Tamil NADU
    • Chennai, Tamil NADU, India, 600035
      • Recruiting
      • Apollo Hospitals; Medical Oncology
  • Telangana
    • Hyderabad, Telangana, India, 500034
      • Recruiting
      • Indo-American Cancer Hospital & Research Center
• Ireland
  • Dublin, Ireland, 8
    • Recruiting
    • St James's Hospital
  • Dublin, Ireland, D24 NR0A
    • Recruiting
    • Adelaide & Meath Hospital, Dublin, Incorporating the National Children's Hospital; Oncology Day Unit
  • Dublin, Ireland, D04 T6F4
    • Recruiting
    • St Vincent'S Uni Hospital; Medical Oncology
• Israel
  • Jerusalem, Israel, 9112001
    • Recruiting
    • Hadassah University Hospital - Ein Kerem
  • Tel Aviv, Israel, 6423906
    • Recruiting
    • Sourasky / Ichilov Hospital; Dept. of Oncology
• Lebanon
  • Beirut, Lebanon, 2063 1111
    • Recruiting
    • Hotel Dieu de France; Oncology
  • Beirut, Lebanon, 1107 2020
    • Recruiting
    • American University of Beirut - Medical Center
  • Saida, Lebanon, 6520
    • Recruiting
    • Hammoud Hospital
• Mexico
  • Mexico City, Mexico, 01120
    • Recruiting
    • The American British Cowdray Hospital/ Hospital Abc; Oncology
  • Mexico CITY (federal District)
    • Ciudad de México, Mexico CITY (federal District), Mexico, 03810
      • Recruiting
      • Oncare Viaducto Napoles
  • Puebla
    • Heroica Puebla de Zaragoza, Puebla, Mexico, 72530
      • Recruiting
      • Clínica Integral Internacional de Oncología S de RL de CV
• Philippines
  • Cebu City, Philippines, 6000
    • Recruiting
    • Cebu Doctors' University Hospital; Research Office
  • Quezon City, Philippines, 1102
    • Recruiting
    • St Lukes Medical Center
• Poland
  • Lublin, Poland, 20-609
    • Withdrawn
    • Instytut Genetyki i Immunologii GENIM
  • Warszawa, Poland, 02-781
    • Recruiting
    • Narodowy Instytut Onkologii im. M. Sklodowskiej-Curie; Oddzial Badan Wczesnych Faz
• Portugal
  • Lisboa, Portugal, 1500-650
    • Withdrawn
    • Hospital da Luz; Departamento de Oncologia Medica
  • Porto, Portugal, 4200-072
    • Recruiting
    • IPO do Porto; Servico de Oncologia Medica
  • Porto, Portugal, 4100-180
    • Recruiting
    • Hospital CUF Porto; Servico Pneumologia
• Saudi Arabia
  • Riyadh, Saudi Arabia, 11426
    • Recruiting
    • National Guard King Abdulaziz Medical City; Oncology
• Serbia
  • Belgrade, Serbia, 11080
    • Recruiting
    • University Hospital Medical Center Bezanijska kosa
  • Belgrade, Serbia
    • Recruiting
    • Oncomed-System
  • Belgrade, Serbia
    • Recruiting
    • SIRIUS Medical
  • Belgrade, Serbia
    • Recruiting
    • Special hospital for internal diseases Vesalius
  • Sremska Kamenica, Serbia, 21204
    • Recruiting
    • Oncology Institute of Vojvodina
• Slovakia
  • Bratislava, Slovakia, 833 10
    • Recruiting
    • Narodny Onkologicky Ustav; Oddelenie klinickej onkologie A
• Slovenia
  • Golnik, Slovenia, 4204
    • Recruiting
    • University Clinic Golnik
  • Ljubljana, Slovenia, 1000
    • Recruiting
    • Institute Of Oncology Ljubljana
• South Africa
  • Johannesburg, South Africa, 2196
    • Recruiting
    • Medical Oncology Centre of Rosebank; Oncology
  • Pretoria, South Africa, 0001
    • Recruiting
    • Wilgers Oncology Centre
• Spain
  • Jaen, Spain, 23007
    • Recruiting
    • Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico; Servicio de Oncologia
  • Madrid, Spain, 28040
    • Withdrawn
    • Fundacion Jimenez Diaz; Servicio de Oncologia
  • Madrid, Spain, 28050
    • Withdrawn
    • HM Sanchinarro ? CIOCC; Servicio de Oncologia
  • Zaragoza, Spain, 50009
    • Recruiting
    • Hospital Universitario Miguel Servet; Servicio Oncologia
  • Islas Baleares
    • Palma De Mallorca, Islas Baleares, Spain, 07014
      • Recruiting
      • Hospital Universitario Son Espases; Servicio de Oncologia
  • Navarra
    • Pamplona, Navarra, Spain, 31008
      • Withdrawn
      • Clinica Universitaria de Navarra; Servicio de Oncologia
• Taiwan
  • Kaohisung, Taiwan, 833
    • Recruiting
    • Chang Gung Medical Foundation - Kaohsiung; Oncology
  • Taipei City, Taiwan, 112
    • Recruiting
    • Taipei Veterans General Hospital
  • Taoyuan County, Taiwan, 333
    • Recruiting
    • Chung Gung Memorial Hospital; Oncology
• Thailand
  • Bangkok, Thailand, 10330
    • Recruiting
    • Chulalongkorn Hospital; Medical Oncology
  • Bangkok, Thailand, 10700
    • Recruiting
    • Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology
• Turkey
  • Ankara, Turkey, 06520
    • Recruiting
    • Memorial Ankara Hastanesi
  • Edirne, Turkey, 22030
    • Recruiting
    • Trakya University Medical Faculty
  • Istanbul, Turkey, 34750
    • Recruiting
    • Medicana International Atasehir Hospital
  • Istanbul, Turkey, 34214
    • Recruiting
    • Ba?c?lar Medipol Mega Üniversite Hastanesi; Oncology
  • Sar?yer/?stanbul, Turkey, 34457
    • Recruiting
    • Ac?badem Maslak Hastanesi Büyükdere
  • Seyhan/Adana, Turkey, 01130
    • Recruiting
    • Ac?badem Adana Hospital, Oncology Department
• United Arab Emirates
  • Dubai, United Arab Emirates
    • Recruiting
    • Mediclinic City Hospital
• United Kingdom
  • Bristol, United Kingdom, BS2 8ED
    • Recruiting
    • Bristol Haematology and Oncology Centre
  • Eastbourne, United Kingdom, BN2 1ES
    • Recruiting
    • Royal Sussex County Hospital; Clinical Research Facility
  • Exeter, United Kingdom, EX2 5DW
    • Recruiting
    • Royal Devon & Exeter Hospital; Oncology Centre
  • London, United Kingdom, SW17 0RE
    • Recruiting
    • St Georges University Hospitals NHS Foundation Trust
  • Manchester, United Kingdom, M2O 4BX
    • Withdrawn
    • Christie Hospital Nhs Trust; Medical Oncology
  • New Castle Upon Tyne, United Kingdom, NE7 7DN
    • Recruiting
    • Freeman Hospital; Northern Centre For Cancer Care
  • Torquay, United Kingdom, TQ2 7AA
    • Recruiting
    • Torbay Hospital; Oncology
• Vietnam
  • Hanoi, Vietnam, 100000
    • Recruiting
    • Hanoi Oncology Hospital
  • Hanoi, Vietnam, 100000
    • Recruiting
    • K hospital
  • Ho Chi Minh City, Vietnam
    • Recruiting
    • Ho Chi Minh City Oncology Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Male and Female adult participants who are diagnosed with solid tumour cancers (at any anatomical location) and at any stage of the disease who have undergone an NGS test.

Description

Inclusion Criteria:

• Participant is an adult (according to the age of majority as defined by local regulations)
• Participant is currently diagnosed with any type of solid tumour cancer, at any stage of the disease, at the enrollment date (informed consent date)
• Participant has undergone NGS testing, no longer than 3 months prior to the enrollment date, irrespective of the availability of test results
• Informed consent has been obtained from the participant or legally authorized representative, as per local regulations

Exclusion Criteria:

-Participant has a prior or current diagnosis of haematological malignancy

Study Plan

How is the study designed?

Design Details

• Observational Models: Other
• Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Overall Survival	From date of registry entry until death, for up to 5 years

Collaborators and Investigators

• Sponsor: Hoffmann-La Roche
• Investigators: Study Director: Clinical Trials, Hoffmann-La Roche

Publications and helpful links

Helpful Links

• Related Info

Study record dates

Study Major Dates

• Study Start (Actual): August 27, 2020
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026

Study Registration Dates

• First Submitted: August 25, 2020
• First Submitted That Met QC Criteria: August 25, 2020
• First Posted (Actual): August 27, 2020

Study Record Updates

• Last Update Posted (Actual): March 27, 2024
• Last Update Submitted That Met QC Criteria: March 26, 2024
• Last Verified: March 1, 2024

More Information

Terms related to this study

• Other Study ID Numbers: MX39897

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Plan Description: Qualified researchers may be granted access to individual patient-level data through the data sharing environment of the Registry.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No