- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04570527
Optimized Cardioprotection Therapy in Obese Subjects With CAD
Effects and Mechanism of Adipokines Cardiac Protection in Obese Patients With Coronary Artery Disease (CAD)
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Contact
- Name: Dongdong Sun, MD, PhD
- Phone Number: 86 29 84775183
- Email: wintersun3@gmail.com
Study Contact Backup
- Name: Wanrong Man, MD
- Phone Number: 86 29 84775183
- Email: manwanrong@gmail.com
Study Locations
-
-
Shaanxi
-
Xi'an, Shaanxi, China, 710032
- Recruiting
- Xijing Hospital
-
Contact:
- Wanrong Man, M.D.
- Phone Number: 86 15352312311
- Email: manwanrong@gmail.com
-
Principal Investigator:
- Dongdong Sun, M.D.,Ph.D
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
coronary artery disease according to the WHO definition With or without percutaneous coronary intervention
Exclusion Criteria:
previous Coronary artery bypass grafting (CABG) cardiomyopathy atrial fibrillation or flutter previous heart surgery severe valvular heart disease disease of the hematopoietic system NYHA functional class IV heart failure at baseline severe renal, lung and liver disease cancer
Study Plan
How is the study designed?
Design Details
- Observational Models: Case-Control
- Time Perspectives: Retrospective
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
Obesity
BMI>=25
|
percutaneous coronary intervention
|
Non-Obesity
BMI<25
|
percutaneous coronary intervention
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Number of patient death during the follow up period
Time Frame: 1 year
|
1 year
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Left ventricular ejection fraction
Time Frame: 1 year
|
1 year
|
Number of target vessel revascularization
Time Frame: 1 year
|
1 year
|
Angina class according to the canadian cardiovascular society (CCS) classification
Time Frame: 1 year
|
1 year
|
Scores on the Seattle angina questionnaire
Time Frame: 1 year
|
1 year
|
six-min walk distance (6MWD)
Time Frame: 1 year
|
1 year
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Dongdong Sun, MD, PhD, Xijing Hospital
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- OB-CAD
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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