De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA) (DEBRA)

April 22, 2026 updated by: NRG Oncology

A Phase III Clinical Trial Evaluating De-Escalation of Breast Radiation for Conservative Treatment of Stage I, Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer

This Phase III Trial evaluates whether breast conservation surgery and endocrine therapy results in a non-inferior rate of invasive or non-invasive ipsilateral breast tumor recurrence (IBTR) compared to breast conservation with breast radiation and endocrine therapy.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Breast conservation therapy for early stage breast cancer has been an important achievement of oncology practice in the last half century and breast radiotherapy (RT) has been essential in its development. Several seminal randomized clinical trials conducted in the 1980's era demonstrated that breast radiotherapy following lumpectomy yielded overall survival outcomes equivalent to mastectomy for treatment of early stage invasive breast cancer leading to the National Institute of Health (NIH) Consensus Conference statement in 1991 supporting breast conservation treatment.This established lumpectomy with RT as an alternative to mastectomy and subsequently the rate of breast conservation for eligible breast cancer patients rose steadily. Shortly thereafter, investigators recognized that the toxicity, patient burden, and geographic barriers associated with the protracted treatment course for breast RT was a potential barrier to breast conservation utilization. Numerous phase III clinical trials were conducted randomizing women post lumpectomy to RT vs. observation aimed at identifying which cases did not derive a significant RT benefit. No such subsets of breast cancer patients were consistently identified, thereby solidifying the standard that breast conservation required both lumpectomy and RT. Two meta-analyses by the Early Breast Cancer Trialists Collaborative Group (EBCTCG) in 2005 and 2011 further reinforced the value of breast RT post lumpectomy by examining the relationship of local recurrence and breast cancer mortality relative to the use of breast RT post lumpectomy. In each analysis, it found for axillary node negative breast cancer patients undergoing breast conservation a small but consistent increase in breast cancer mortality when breast radiotherapy was omitted. As a result, breast RT after lumpectomy has become an established paradigm for breast conservation for early stage breast cancer and is recommended by the NCCN 2018 guidelines (as it has for nearly two decades) that are commonly used today by clinicians and health systems alike. The landscape of early stage breast cancer has changed dramatically over the past three decades since the establishment of breast conservation. Widespread screening with mammography has led to the diagnosis of smaller and earlier stage disease. All breast cancers are now routinely characterized by their hormone sensitivity based on the presence of estrogen and progesterone receptors on tumor cells within the biopsy or surgical specimen and presence of HER2 (human epidermal growth factor receptor 2) which has provided an additional means of stratifying breast cancer into distinct prognostic groups. Small, node negative invasive breast cancer that is hormone sensitive (HS) and HER2-negative has a lower overall recurrence rate (local, regional, and distant) than breast cancers characterized by more adverse clinical pathologic features. However, other than in a smaller subset of women greater than 70 years old, clinical trials in this HS population still demonstrated unacceptable local recurrence risks long term after lumpectomy alone emphasizing that clinical and pathologic features are insufficient for consistently identifying when RT can safely be omitted.

Study Type

Interventional

Enrollment (Estimated)

1670

Phase

  • Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

  • Name: Norman Wolmark, MD

Study Locations

  • Canada
    • New Brunswick
      • Saint John, New Brunswick, Canada, E2L 4L2
        • Recruiting
        • Atlantic Health Sciences Corporation-Saint John Regional Hospital
        • Principal Investigator:
          • Farah Naz
        • Contact:
          • Site Public Contact
          • Phone Number: 506-648-6890
    • Ontario
      • Kingston, Ontario, Canada, K7L 2V7
        • Recruiting
        • Kingston Health Sciences Centre
        • Contact:
        • Principal Investigator:
          • Timothy Owen
      • Toronto, Ontario, Canada, M4N 3M5
        • Recruiting
        • Odette Cancer Centre- Sunnybrook Health Sciences Centre
        • Contact:
          • Site Public Contact
          • Phone Number: 416-480-5000
        • Principal Investigator:
          • Eileen Rakovitch
    • Quebec
      • Montreal, Quebec, Canada, H2X 3E4
        • Recruiting
        • CHUM - Centre hospitalier de l'Universite de Montreal
        • Contact:
        • Principal Investigator:
          • Jean-Marc Bourque
      • Québec, Quebec, Canada, G1R 2J6
        • Recruiting
        • CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)
        • Contact:
        • Principal Investigator:
          • Valerie Theberge
    • Saskatchewan
      • Regina, Saskatchewan, Canada, S4T 7T1
        • Recruiting
        • Allan Blair Cancer Centre
        • Principal Investigator:
          • Derek Suderman
        • Contact:
          • Site Public Contact
          • Phone Number: 306-766-2213
      • Saskatoon, Saskatchewan, Canada, S7N 4H4
        • Recruiting
        • Saskatoon Cancer Centre
        • Principal Investigator:
          • Ali A. El-Gayed
        • Contact:
          • Site Public Contact
          • Phone Number: 306-655-2914
  • Hong Kong
      • Chai Wan, Hong Kong
        • Suspended
        • Pamela Youde Nethersole Eastern Hospital
  • Japan
      • Hiroshima, Japan, 734-8551
        • Recruiting
        • Hiroshima University Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 82-424-6042
        • Principal Investigator:
          • Hideo Shigematsu
      • Kyoto, Japan, 606-8507
        • Recruiting
        • Kyoto University Hospital
        • Principal Investigator:
          • Norikazu Masuda
        • Contact:
          • Site Public Contact
          • Phone Number: 81-75-751-3111
      • Matsuyama, Japan, 791-0280
        • Recruiting
        • Shikoku Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 089-999-1172
        • Principal Investigator:
          • Daisuke Takabatake
      • Nagoya, Japan, 466-0065
        • Recruiting
        • Nagoya University Hospital
        • Principal Investigator:
          • Yuko Takano
        • Contact:
          • Site Public Contact
          • Phone Number: 81 52-741-2111
      • Osaka, Japan, 589 8511
        • Recruiting
        • Kindai University
        • Contact:
          • Site Public Contact
          • Phone Number: 072-366-0221
        • Principal Investigator:
          • Yoshifumi Komoike
      • Saitama, Japan, 350-1298
        • Recruiting
        • Saitama Medical University International Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 81-49-276-2028
        • Principal Investigator:
          • Akihiro Fujimoto
      • Tokyo, Japan, 104 0045
        • Recruiting
        • National Cancer Center Hospital
        • Contact:
        • Principal Investigator:
          • Shin Takayama
    • Ehime
      • Tōon, Ehime, Japan, 791-0295
        • Recruiting
        • Ehime University Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: (081) 089-964-5111
        • Principal Investigator:
          • Yoshiaki Kamei
    • Hokkaido
      • Sapporo, Hokkaido, Japan, 060-8648
        • Recruiting
        • Hokkaido University Hospital
        • Principal Investigator:
          • Masato Takahashi
        • Contact:
    • Hyōgo
      • Akashi, Hyōgo, Japan, 673-8558
        • Recruiting
        • Hyogo Cancer Center
        • Principal Investigator:
          • Koji Matsumoto
        • Contact:
          • Site Public Contact
          • Phone Number: 81 78-929-1151
    • Maebashi
      • Gunma, Maebashi, Japan, 371-8511
        • Recruiting
        • Gunma University Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 81-27-220-7626
        • Principal Investigator:
          • Sasagu Kurozumi
    • Tokyo
      • Koto-ku, Tokyo, Japan, 135-8550
        • Recruiting
        • The Cancer Institute Hospital of Jfcr
        • Contact:
        • Principal Investigator:
          • Takehiko Sakai
  • United States
    • Alabama
      • Birmingham, Alabama, United States, 35233
        • Active, not recruiting
        • University of Alabama at Birmingham Cancer Center
      • Mobile, Alabama, United States, 36688
        • Recruiting
        • University of South Alabama Mitchell Cancer Institute
        • Contact:
        • Principal Investigator:
          • Ayesha Munir
    • Arizona
      • Kingman, Arizona, United States, 86401
        • Recruiting
        • Kingman Regional Medical Center
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Phoenix, Arizona, United States, 85004
      • Phoenix, Arizona, United States, 85054
        • Active, not recruiting
        • Mayo Clinic Hospital in Arizona
    • Arkansas
      • Little Rock, Arkansas, United States, 72205
        • Recruiting
        • University of Arkansas for Medical Sciences
        • Contact:
          • Site Public Contact
          • Phone Number: 501-686-8274
        • Principal Investigator:
          • Sanjay Maraboyina
    • California
      • Anaheim, California, United States, 92806
        • Recruiting
        • Kaiser Permanente-Anaheim
        • Contact:
        • Principal Investigator:
          • Aakash Batra
      • Antioch, California, United States, 94531
        • Recruiting
        • Kaiser Permanente-Deer Valley Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Arroyo Grande, California, United States, 93420
        • Recruiting
        • PCR Oncology
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Arroyo Grande, California, United States, 93420
      • Auburn, California, United States, 95602
      • Auburn, California, United States, 95603
        • Recruiting
        • Sutter Cancer Centers Radiation Oncology Services-Auburn
        • Principal Investigator:
          • Kristie A. Bobolis
        • Contact:
      • Bellflower, California, United States, 90706
        • Recruiting
        • Kaiser Permanente-Bellflower
        • Contact:
        • Principal Investigator:
          • Aakash Batra
      • Berkeley, California, United States, 94704
        • Recruiting
        • Alta Bates Summit Medical Center-Herrick Campus
        • Principal Investigator:
          • Kristie A. Bobolis
        • Contact:
      • Beverly Hills, California, United States, 90211
        • Suspended
        • Tower Cancer Research Foundation
      • Carmichael, California, United States, 95608
        • Recruiting
        • Mercy San Juan Medical Center
        • Principal Investigator:
          • Matthew D. Wheatley
        • Contact:
      • Carmichael, California, United States, 95608
      • Dublin, California, United States, 94568
        • Recruiting
        • Kaiser Permanente Dublin
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
        • Principal Investigator:
          • Samantha A. Seaward
      • Dublin, California, United States, 94568
        • Active, not recruiting
        • Epic Care-Dublin
      • Elk Grove, California, United States, 95758
      • Emeryville, California, United States, 94608
        • Active, not recruiting
        • Bay Area Breast Surgeons Inc
      • Emeryville, California, United States, 94608
        • Active, not recruiting
        • Epic Care Partners in Cancer Care
      • Fremont, California, United States, 94538
      • Fremont, California, United States, 94538
        • Recruiting
        • Kaiser Permanente-Fremont
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Fremont, California, United States, 94538
        • Recruiting
        • Washington Hospital
        • Principal Investigator:
          • Emi J. Yoshida
        • Contact:
          • Site Public Contact
          • Phone Number: 510-745-6433
      • Fresno, California, United States, 93720
        • Recruiting
        • Kaiser Permanente-Fresno
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Fresno, California, United States, 93720
        • Recruiting
        • Fresno Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Fresno, California, United States, 93720
        • Recruiting
        • Kaiser Permanente Fresno Orchard Plaza
        • Principal Investigator:
          • Samantha A. Seaward
        • Contact:
          • Site Public Contact
          • Phone Number: 833-574-2273
      • Irvine, California, United States, 92612
        • Recruiting
        • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
        • Principal Investigator:
          • Rita S. Mehta
        • Contact:
      • Los Angeles, California, United States, 90048
        • Recruiting
        • Cedars Sinai Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 310-423-8965
        • Principal Investigator:
          • Julie Jang
      • Los Angeles, California, United States, 90027
        • Recruiting
        • Kaiser Permanente Los Angeles Medical Center
        • Contact:
        • Principal Investigator:
          • Aakash Batra
      • Los Angeles, California, United States, 90033
        • Recruiting
        • USC / Norris Comprehensive Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 323-865-0451
        • Principal Investigator:
          • Diane C. Ling
      • Los Angeles, California, United States, 90033
        • Recruiting
        • Los Angeles General Medical Center
        • Principal Investigator:
          • Diane C. Ling
        • Contact:
      • Martinez, California, United States, 94553-3156
        • Active, not recruiting
        • Contra Costa Regional Medical Center
      • Modesto, California, United States, 95355
      • Modesto, California, United States, 95356
        • Recruiting
        • Kaiser Permanente-Modesto
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Modesto, California, United States, 95356
        • Recruiting
        • Kaiser Permanente- Modesto MOB II
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
        • Principal Investigator:
          • Samantha A. Seaward
      • Mountain View, California, United States, 94040
        • Recruiting
        • Palo Alto Medical Foundation-Camino Division
        • Principal Investigator:
          • Kristie A. Bobolis
        • Contact:
      • Oakland, California, United States, 94611
        • Recruiting
        • Kaiser Permanente-Oakland
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Oakland, California, United States, 94611
        • Recruiting
        • Kaiser Permanente Oakland-Broadway
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Oakland, California, United States, 94609
        • Active, not recruiting
        • Bay Area Tumor Institute
      • Ontario, California, United States, 91761
        • Recruiting
        • Kaiser Permanente-Ontario
        • Contact:
        • Principal Investigator:
          • Aakash Batra
      • Orange, California, United States, 92868
        • Recruiting
        • Saint Joseph Hospital - Orange
        • Contact:
          • Site Public Contact
          • Phone Number: 714-734-6220
        • Principal Investigator:
          • Timothy E. Byun
      • Orange, California, United States, 92868
        • Recruiting
        • UC Irvine Health/Chao Family Comprehensive Cancer Center
        • Principal Investigator:
          • Rita S. Mehta
        • Contact:
      • Palo Alto, California, United States, 94301
        • Recruiting
        • Palo Alto Medical Foundation Health Care
        • Principal Investigator:
          • Kristie A. Bobolis
        • Contact:
      • Palo Alto, California, United States, 94304
        • Recruiting
        • Stanford Cancer Institute Palo Alto
        • Principal Investigator:
          • Irene L. Wapnir
        • Contact:
      • Pasadena, California, United States, 91105
        • Suspended
        • Huntington Memorial Hospital
      • Rancho Cordova, California, United States, 95670
        • Recruiting
        • Kaiser Permanente-Rancho Cordova Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Redwood City, California, United States, 94063
        • Recruiting
        • Kaiser Permanente- Marshall Medical Offices
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
        • Principal Investigator:
          • Samantha A. Seaward
      • Richmond, California, United States, 94801
        • Recruiting
        • Kaiser Permanente-Richmond
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Riverside, California, United States, 92505
        • Recruiting
        • Kaiser Permanente-Riverside
        • Contact:
        • Principal Investigator:
          • Aakash Batra
      • Rocklin, California, United States, 95765
      • Rohnert Park, California, United States, 94928
        • Recruiting
        • Rohnert Park Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Roseville, California, United States, 95661
        • Recruiting
        • Kaiser Permanente-Roseville
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Roseville, California, United States, 95661
        • Recruiting
        • Sutter Cancer Centers Radiation Oncology Services-Roseville
        • Principal Investigator:
          • Kristie A. Bobolis
        • Contact:
      • Roseville, California, United States, 95661
      • Roseville, California, United States, 95678
        • Recruiting
        • The Permanente Medical Group-Roseville Radiation Oncology
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Sacramento, California, United States, 95817
        • Recruiting
        • University of California Davis Comprehensive Cancer Center
        • Principal Investigator:
          • Xiao Zhao
        • Contact:
          • Site Public Contact
          • Phone Number: 916-734-3089
      • Sacramento, California, United States, 95814
        • Recruiting
        • Kaiser Permanente Downtown Commons
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Sacramento, California, United States, 95816
      • Sacramento, California, United States, 95823
        • Recruiting
        • Kaiser Permanente-South Sacramento
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Sacramento, California, United States, 95816
      • Sacramento, California, United States, 95823
        • Recruiting
        • South Sacramento Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • San Francisco, California, United States, 94115
        • Recruiting
        • California Pacific Medical Center-Pacific Campus
        • Principal Investigator:
          • Kristie A. Bobolis
        • Contact:
      • San Francisco, California, United States, 94115
        • Recruiting
        • Kaiser Permanente-San Francisco
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • San Jose, California, United States, 95119
        • Recruiting
        • Kaiser Permanente-Santa Teresa-San Jose
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • San Jose, California, United States, 95124
        • Recruiting
        • Stanford Cancer Center South Bay
        • Principal Investigator:
          • Irene L. Wapnir
        • Contact:
      • San Leandro, California, United States, 94577
        • Recruiting
        • Kaiser Permanente San Leandro
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • San Luis Obispo, California, United States, 93401
      • San Rafael, California, United States, 94903
        • Recruiting
        • Kaiser San Rafael-Gallinas
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Santa Barbara, California, United States, 93105
      • Santa Clara, California, United States, 95051
        • Recruiting
        • Kaiser Permanente Medical Center - Santa Clara
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Santa Clarita, California, United States, 91355
        • Recruiting
        • USC Norris Santa Clarita Oncology
        • Principal Investigator:
          • Diane C. Ling
        • Contact:
          • Site Public Contact
          • Phone Number: 661-839-1810
      • Santa Cruz, California, United States, 95065
        • Recruiting
        • Palo Alto Medical Foundation-Santa Cruz
        • Principal Investigator:
          • Kristie A. Bobolis
        • Contact:
      • Santa Cruz, California, United States, 95065
        • Recruiting
        • Dominican Santa Cruz Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 831-462-7770
        • Principal Investigator:
          • Michael P. Alexander
      • Santa Maria, California, United States, 93444
      • Santa Rosa, California, United States, 95403
        • Recruiting
        • Sutter Pacific Medical Foundation
        • Principal Investigator:
          • Kristie A. Bobolis
        • Contact:
      • Santa Rosa, California, United States, 95403
        • Recruiting
        • Kaiser Permanente-Santa Rosa
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • South San Francisco, California, United States, 94080
        • Recruiting
        • Kaiser Permanente-South San Francisco
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • South San Francisco, California, United States, 94080
        • Recruiting
        • Kaiser Permanente Cancer Treatment Center
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • St. Helena, California, United States, 94574
        • Recruiting
        • Saint Helena Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 707-967-3698
        • Principal Investigator:
          • Ethan D. Schram
      • Stockton, California, United States, 95210
        • Recruiting
        • Kaiser Permanente-Stockton
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Sunnyvale, California, United States, 94086
      • Tarzana, California, United States, 91356
        • Recruiting
        • Cedars-Sinai Cancer - Tarzana
        • Contact:
          • Site Public Contact
          • Phone Number: 818-981-3818
        • Principal Investigator:
          • Julie Jang
      • Torrance, California, United States, 90509
        • Suspended
        • Torrance Memorial Medical Center
      • Torrance, California, United States, 90505
        • Recruiting
        • Torrance Memorial Physician Network - Cancer Care
        • Contact:
        • Principal Investigator:
          • Julie Jang
      • Truckee, California, United States, 96161
        • Recruiting
        • Gene Upshaw Memorial Tahoe Forest Cancer Center
        • Principal Investigator:
          • Xiao Zhao
        • Contact:
          • Site Public Contact
          • Phone Number: 530-582-6450
      • Vacaville, California, United States, 95688
        • Recruiting
        • Kaiser Permanente Medical Center-Vacaville
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Vallejo, California, United States, 94589
        • Recruiting
        • Kaiser Permanente-Vallejo
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Vallejo, California, United States, 94589
        • Recruiting
        • Sutter Solano Medical Center/Cancer Center
        • Principal Investigator:
          • Kristie A. Bobolis
        • Contact:
      • Walnut Creek, California, United States, 94596
        • Recruiting
        • Kaiser Permanente-Walnut Creek
        • Contact:
          • Site Public Contact
          • Phone Number: 877-642-4691
          • Email: Kpoct@kp.org
        • Principal Investigator:
          • Samantha A. Seaward
      • Woodland, California, United States, 95695
    • Colorado
      • Aurora, Colorado, United States, 80045
        • Recruiting
        • UCHealth University of Colorado Hospital
        • Principal Investigator:
          • Rachel A. Rabinovitch
        • Contact:
          • Site Public Contact
          • Phone Number: 720-848-0650
      • Boulder, Colorado, United States, 80304
        • Active, not recruiting
        • Rocky Mountain Cancer Centers-Boulder
      • Colorado Springs, Colorado, United States, 80907
      • Colorado Springs, Colorado, United States, 80909
        • Recruiting
        • UCHealth Memorial Hospital Central
        • Principal Investigator:
          • Rachel A. Rabinovitch
        • Contact:
          • Site Public Contact
          • Phone Number: 719-365-2406
      • Colorado Springs, Colorado, United States, 80923
      • Denver, Colorado, United States, 80220
        • Recruiting
        • Rose Medical Center
        • Principal Investigator:
          • Andrew S. Kennedy
        • Contact:
      • Denver, Colorado, United States, 80206
        • Recruiting
        • UCHealth - Cherry Creek
        • Principal Investigator:
          • Rachel A. Rabinovitch
        • Contact:
      • Denver, Colorado, United States, 80210
        • Suspended
        • AdventHealth Porter
      • Dillon, Colorado, United States, 80435
        • Recruiting
        • Dillon Health Center/Shaw Cancer Center
        • Principal Investigator:
          • Patricia H. Hardenbergh
        • Contact:
          • Site Public Contact
          • Phone Number: 970-470-7170
      • Edwards, Colorado, United States, 81632
        • Recruiting
        • Shaw Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 970-569-7429
        • Principal Investigator:
          • Patricia H. Hardenbergh
      • Englewood, Colorado, United States, 80113
        • Suspended
        • Swedish Medical Center
      • Englewood, Colorado, United States, 80113
        • Active, not recruiting
        • Mountain Blue Cancer Care Center - Swedish
      • Englewood, Colorado, United States, 80113
        • Active, not recruiting
        • The Melanoma and Skin Cancer Institute
      • Fort Collins, Colorado, United States, 80524
        • Recruiting
        • Poudre Valley Hospital
        • Principal Investigator:
          • Rachel A. Rabinovitch
        • Contact:
          • Site Public Contact
          • Phone Number: 970-297-6150
      • Fort Collins, Colorado, United States, 80528
        • Recruiting
        • Cancer Care and Hematology-Fort Collins
        • Principal Investigator:
          • Rachel A. Rabinovitch
        • Contact:
      • Golden, Colorado, United States, 80401
        • Recruiting
        • Lutheran Hospital - Cancer Centers of Colorado
        • Principal Investigator:
          • Karng S. Log
        • Contact:
      • Greeley, Colorado, United States, 80631
        • Recruiting
        • UCHealth Greeley Hospital
        • Principal Investigator:
          • Rachel A. Rabinovitch
        • Contact:
      • Highlands Ranch, Colorado, United States, 80129
        • Recruiting
        • UCHealth Highlands Ranch Hospital
        • Principal Investigator:
          • Rachel A. Rabinovitch
        • Contact:
          • Site Public Contact
          • Phone Number: 720-848-0650
      • Littleton, Colorado, United States, 80122
        • Suspended
        • AdventHealth Littleton
      • Lone Tree, Colorado, United States, 80124
        • Recruiting
        • UCHealth Lone Tree Health Center
        • Principal Investigator:
          • Rachel A. Rabinovitch
        • Contact:
      • Longmont, Colorado, United States, 80501
      • Loveland, Colorado, United States, 80538
        • Recruiting
        • Medical Center of the Rockies
        • Principal Investigator:
          • Rachel A. Rabinovitch
        • Contact:
          • Site Public Contact
          • Phone Number: 970-203-7083
      • Parker, Colorado, United States, 80138
        • Suspended
        • AdventHealth Parker
      • Westminster, Colorado, United States, 80023
    • Connecticut
      • Derby, Connecticut, United States, 06418
        • Recruiting
        • Smilow Cancer Hospital-Derby Care Center
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Fairfield, Connecticut, United States, 06824
        • Recruiting
        • Smilow Cancer Hospital Care Center-Fairfield
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Glastonbury, Connecticut, United States, 06033
        • Recruiting
        • Smilow Cancer Hospital Care Center at Glastonbury
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Greenwich, Connecticut, United States, 06830
        • Recruiting
        • Smilow Cancer Hospital Care Center at Greenwich
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Guilford, Connecticut, United States, 06437
        • Recruiting
        • Smilow Cancer Hospital Care Center - Guilford
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Hamden, Connecticut, United States, 06518
        • Recruiting
        • Smilow Cancer Hospital-Hamden Care Center
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Hartford, Connecticut, United States, 06105
        • Recruiting
        • Smilow Cancer Hospital Care Center at Saint Francis
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • New Haven, Connecticut, United States, 06520
        • Recruiting
        • Yale University
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • New Haven, Connecticut, United States, 06511
        • Recruiting
        • Yale-New Haven Hospital Saint Raphael Campus
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • North Haven, Connecticut, United States, 06473
        • Recruiting
        • Yale-New Haven Hospital North Haven Medical Center
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Orange, Connecticut, United States, 06477
        • Recruiting
        • Smilow Cancer Hospital-Orange Care Center
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Stamford, Connecticut, United States, 06902
        • Recruiting
        • Smilow Cancer Hospital Care Center at Long Ridge
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Torrington, Connecticut, United States, 06790
        • Recruiting
        • Smilow Cancer Hospital-Torrington Care Center
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Trumbull, Connecticut, United States, 06611
        • Recruiting
        • Smilow Cancer Hospital Care Center-Trumbull
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Waterbury, Connecticut, United States, 06708
        • Recruiting
        • Smilow Cancer Hospital-Waterbury Care Center
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
      • Waterford, Connecticut, United States, 06385
        • Recruiting
        • Smilow Cancer Hospital Care Center - Waterford
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
    • Delaware
      • Lewes, Delaware, United States, 19958
        • Active, not recruiting
        • Beebe Medical Center
      • Millville, Delaware, United States, 19967
        • Active, not recruiting
        • Beebe South Coastal Health Campus
      • Newark, Delaware, United States, 19713
        • Active, not recruiting
        • Helen F Graham Cancer Center
      • Newark, Delaware, United States, 19713
        • Active, not recruiting
        • Medical Oncology Hematology Consultants PA
      • Newark, Delaware, United States, 19713
        • Active, not recruiting
        • Delaware Clinical and Laboratory Physicians PA
      • Newark, Delaware, United States, 19718
        • Active, not recruiting
        • Christiana Care Health System-Christiana Hospital
      • Rehoboth Beach, Delaware, United States, 19971
        • Active, not recruiting
        • Beebe Health Campus
    • District of Columbia
      • Washington D.C., District of Columbia, United States, 20007
        • Recruiting
        • MedStar Georgetown University Hospital
        • Principal Investigator:
          • Paul B. Fowler
        • Contact:
          • Site Public Contact
          • Phone Number: 202-444-2223
      • Washington D.C., District of Columbia, United States, 20010
        • Recruiting
        • Medstar Washington Hospital Center
        • Principal Investigator:
          • Paul B. Fowler
        • Contact:
          • Site Public Contact
          • Phone Number: 202-877-8839
      • Washington D.C., District of Columbia, United States, 20037
        • Recruiting
        • George Washington University Medical Center
        • Principal Investigator:
          • Sharad Goyal
        • Contact:
          • Site Public Contact
          • Phone Number: 202-741-2210
    • Florida
      • Altamonte Springs, Florida, United States, 32701
        • Recruiting
        • AdventHealth Altamonte
        • Principal Investigator:
          • Catherine S. Hwang
        • Contact:
          • Site Public Contact
          • Phone Number: 407-303-2200
      • Aventura, Florida, United States, 33180
        • Recruiting
        • Mount Sinai Comprehensive Cancer Center at Aventura
        • Contact:
        • Principal Investigator:
          • Debra L. Linzer
      • Aventura, Florida, United States, 33180
        • Suspended
        • GenesisCare USA - Aventura FP
      • Aventura, Florida, United States, 33180
        • Suspended
        • GenesisCare USA - Aventura
      • Bradenton, Florida, United States, 34205
        • Recruiting
        • Florida Cancer Specialists - Bradenton Cancer Center
        • Contact:
        • Principal Investigator:
          • Kunal Saigal
      • Coral Gables, Florida, United States, 33146
        • Recruiting
        • UM Sylvester Comprehensive Cancer Center at Coral Gables
        • Principal Investigator:
          • Cristiane Takita
        • Contact:
          • Site Public Contact
          • Phone Number: 305-243-2647
      • Deerfield Beach, Florida, United States, 33442
        • Recruiting
        • UM Sylvester Comprehensive Cancer Center at Deerfield Beach
        • Principal Investigator:
          • Cristiane Takita
        • Contact:
          • Site Public Contact
          • Phone Number: 305-243-2647
      • Doral, Florida, United States, 33166
        • Recruiting
        • UM Sylvester Comprehensive Cancer Center at Doral
        • Principal Investigator:
          • Cristiane Takita
        • Contact:
      • Fort Myers, Florida, United States, 33905
        • Recruiting
        • Regional Cancer Center-Lee Memorial Health System
        • Contact:
        • Principal Investigator:
          • Leandro P. Moraes
      • Gainesville, Florida, United States, 32610
        • Recruiting
        • UF Health Cancer Institute - Gainesville
        • Principal Investigator:
          • Tithi Biswas
        • Contact:
      • Jacksonville, Florida, United States, 32224-9980
        • Active, not recruiting
        • Mayo Clinic in Florida
      • Lakeland, Florida, United States, 33805
        • Recruiting
        • The Watson Clinic
        • Principal Investigator:
          • Shalini Mulaparthi
        • Contact:
          • Site Public Contact
          • Phone Number: 863-680-7780
      • Miami, Florida, United States, 33136
        • Recruiting
        • University of Miami Miller School of Medicine-Sylvester Cancer Center
        • Principal Investigator:
          • Cristiane Takita
        • Contact:
          • Site Public Contact
          • Phone Number: 305-243-2647
      • Miami Beach, Florida, United States, 33140
        • Recruiting
        • Mount Sinai Medical Center
        • Contact:
        • Principal Investigator:
          • Debra L. Linzer
      • N. Venice, Florida, United States, 34275
        • Recruiting
        • Sarasota Memorial Hospital-Venice
        • Principal Investigator:
          • Kunal Saigal
        • Contact:
          • Site Public Contact
          • Phone Number: 941-261-9000
      • Ocoee, Florida, United States, 34761
        • Recruiting
        • Health Central
        • Principal Investigator:
          • Patrick Kelly
        • Contact:
      • Orlando, Florida, United States, 32803
        • Recruiting
        • AdventHealth Orlando
        • Principal Investigator:
          • Catherine S. Hwang
        • Contact:
      • Orlando, Florida, United States, 32806
      • Plantation, Florida, United States, 33324
        • Recruiting
        • UM Sylvester Comprehensive Cancer Center at Plantation
        • Principal Investigator:
          • Cristiane Takita
        • Contact:
          • Site Public Contact
          • Phone Number: 305-243-2647
      • Plantation, Florida, United States, 33324
        • Suspended
        • GenesisCare USA - Plantation
      • Sarasota, Florida, United States, 34232
        • Recruiting
        • Florida Cancer Specialists - Sarasota
        • Contact:
        • Principal Investigator:
          • Kunal Saigal
      • Sarasota, Florida, United States, 34236
        • Recruiting
        • Florida Cancer Specialists - Sarasota Downtown
        • Contact:
          • Site Public Contact
          • Phone Number: 941-957-1000
        • Principal Investigator:
          • Kunal Saigal
      • Sarasota, Florida, United States, 34239
        • Recruiting
        • Sarasota Memorial Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 941-917-2225
        • Principal Investigator:
          • Kunal Saigal
      • Sarasota, Florida, United States, 34243
        • Recruiting
        • Sarasota Memorial Health Care Center at University Parkway
        • Principal Investigator:
          • Kunal Saigal
        • Contact:
          • Site Public Contact
          • Phone Number: 941-917-6519
      • Sarasota, Florida, United States, 34239
        • Recruiting
        • First Physicians Group-Sarasota
        • Principal Investigator:
          • Kunal Saigal
        • Contact:
          • Site Public Contact
          • Phone Number: 941-917-8383
      • Sarasota, Florida, United States, 34239
        • Recruiting
        • First Physicians Group - Urology Robotic and Minimally Invasive Surgery
        • Principal Investigator:
          • Kunal Saigal
        • Contact:
          • Site Public Contact
          • Phone Number: 941-917-5400
      • Sarasota, Florida, United States, 34232
        • Recruiting
        • Intercoastal Medical Group - Cattleridge II
        • Principal Investigator:
          • Kunal Saigal
        • Contact:
          • Site Public Contact
          • Phone Number: 941-200-1125
      • Sarasota, Florida, United States, 34239
        • Recruiting
        • First Physicians Group - Silverstein Institute at Floyd Street
        • Principal Investigator:
          • Kunal Saigal
        • Contact:
      • Tampa, Florida, United States, 33607
        • Recruiting
        • Saint Joseph's Hospital/Children's Hospital-Tampa
        • Principal Investigator:
          • Nitesh Paryani
        • Contact:
      • Tampa, Florida, United States, 33606
        • Active, not recruiting
        • Tampa General Hospital
      • Venice, Florida, United States, 34285
        • Recruiting
        • Florida Cancer Specialists - Venice Island
        • Contact:
        • Principal Investigator:
          • Kunal Saigal
      • Venice, Florida, United States, 34275
        • Recruiting
        • Florida Cancer Specialists - Venice Pinebrook
        • Contact:
        • Principal Investigator:
          • Kunal Saigal
      • Weston, Florida, United States, 33331
        • Recruiting
        • Cleveland Clinic-Weston
        • Principal Investigator:
          • Saju A. Rajan
        • Contact:
      • Winter Haven, Florida, United States, 33881
        • Recruiting
        • Winter Haven Hospital
        • Principal Investigator:
          • Nitesh Paryani
        • Contact:
    • Georgia
      • Alpharetta, Georgia, United States, 30005
        • Recruiting
        • Northside Hospital-Alpharetta
        • Principal Investigator:
          • Amelia B. Zelnak
        • Contact:
      • Atlanta, Georgia, United States, 30322
        • Recruiting
        • Emory University Hospital/Winship Cancer Institute
        • Principal Investigator:
          • Jolinta Y. Lin
        • Contact:
          • Site Public Contact
          • Phone Number: 404-778-1868
      • Atlanta, Georgia, United States, 30342
        • Recruiting
        • Northside Hospital
        • Principal Investigator:
          • Amelia B. Zelnak
        • Contact:
      • Atlanta, Georgia, United States, 30303
        • Recruiting
        • Grady Health System
        • Principal Investigator:
          • Jolinta Y. Lin
        • Contact:
          • Site Public Contact
          • Phone Number: 404-778-1868
      • Atlanta, Georgia, United States, 30308
        • Recruiting
        • Emory University Hospital Midtown
        • Principal Investigator:
          • Jolinta Y. Lin
        • Contact:
          • Site Public Contact
          • Phone Number: 888-946-7447
      • Atlanta, Georgia, United States, 30342
        • Recruiting
        • Emory Saint Joseph's Hospital
        • Principal Investigator:
          • Jolinta Y. Lin
        • Contact:
          • Site Public Contact
          • Phone Number: 404-851-7115
      • Atlanta, Georgia, United States, 30309
        • Recruiting
        • Piedmont Hospital
        • Contact:
        • Principal Investigator:
          • Adam W. Nowlan
      • Canton, Georgia, United States, 30115
        • Recruiting
        • Northside Hospital-Cherokee
        • Principal Investigator:
          • Amelia B. Zelnak
        • Contact:
      • Cumming, Georgia, United States, 30041
        • Recruiting
        • Northside Hospital-Forsyth
        • Principal Investigator:
          • Amelia B. Zelnak
        • Contact:
      • Decatur, Georgia, United States, 30033
      • Fayetteville, Georgia, United States, 30214
        • Recruiting
        • Piedmont Fayette Hospital
        • Contact:
        • Principal Investigator:
          • Adam W. Nowlan
      • Johns Creek, Georgia, United States, 30097
        • Recruiting
        • Emory Johns Creek Hospital
        • Principal Investigator:
          • Jolinta Y. Lin
        • Contact:
      • Newnan, Georgia, United States, 30265
        • Recruiting
        • Piedmont Newnan Hospital
        • Principal Investigator:
          • Adam W. Nowlan
        • Contact:
      • Savannah, Georgia, United States, 31405
        • Recruiting
        • Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
        • Contact:
        • Principal Investigator:
          • John L. Mikell
      • Stockbridge, Georgia, United States, 30281
        • Recruiting
        • Piedmont Henry Hospital
        • Principal Investigator:
          • Adam W. Nowlan
        • Contact:
          • Site Public Contact
          • Phone Number: 404-425-1800
    • Hawaii
      • Honolulu, Hawaii, United States, 96826
        • Recruiting
        • Kapiolani Medical Center for Women and Children
        • Contact:
          • Site Public Contact
          • Phone Number: 808-983-6090
        • Principal Investigator:
          • Jami A. Fukui
      • Honolulu, Hawaii, United States, 96813
        • Recruiting
        • Hawaii Cancer Care Inc - Waterfront Plaza
        • Contact:
        • Principal Investigator:
          • Jami A. Fukui
      • Honolulu, Hawaii, United States, 96813
        • Recruiting
        • Queen's Cancer Cenrer - POB I
        • Contact:
          • Site Public Contact
          • Phone Number: 808-532-0315
        • Principal Investigator:
          • Jami A. Fukui
      • Honolulu, Hawaii, United States, 96813
        • Recruiting
        • Queen's Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 808-545-8548
        • Principal Investigator:
          • Jami A. Fukui
      • Honolulu, Hawaii, United States, 96813
        • Recruiting
        • Straub Clinic and Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 808-522-4333
        • Principal Investigator:
          • Jami A. Fukui
      • Honolulu, Hawaii, United States, 96813
        • Recruiting
        • University of Hawaii Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 808-586-2979
        • Principal Investigator:
          • Jami A. Fukui
      • Honolulu, Hawaii, United States, 96817
        • Recruiting
        • Kuakini Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 808-547-9816
        • Principal Investigator:
          • Jami A. Fukui
      • Honolulu, Hawaii, United States, 96817
        • Recruiting
        • Queen's Cancer Center - Kuakini
        • Contact:
          • Site Public Contact
          • Phone Number: 808-531-8521
        • Principal Investigator:
          • Jami A. Fukui
      • Honolulu, Hawaii, United States, 96817
        • Recruiting
        • The Cancer Center of Hawaii-Liliha
        • Contact:
          • Site Public Contact
          • Phone Number: 808-547-6881
        • Principal Investigator:
          • Jami A. Fukui
      • Honolulu, Hawaii, United States, 96819
        • Recruiting
        • Kaiser Permanente Moanalua Medical Center
        • Contact:
        • Principal Investigator:
          • Samantha A. Seaward
      • Honolulu, Hawaii, United States, 96817
        • Suspended
        • Hawaii Cancer Care Inc-Liliha
      • Kailua, Hawaii, United States, 96734
        • Suspended
        • Castle Medical Center
      • Lihue, Hawaii, United States, 96766
        • Recruiting
        • Wilcox Memorial Hospital and Kauai Medical Clinic
        • Contact:
          • Site Public Contact
          • Phone Number: 808-535-7960
        • Principal Investigator:
          • Jami A. Fukui
      • ‘Aiea, Hawaii, United States, 96701
        • Recruiting
        • Hawaii Cancer Care - Westridge
        • Contact:
        • Principal Investigator:
          • Jami A. Fukui
      • ‘Aiea, Hawaii, United States, 96701
        • Recruiting
        • Pali Momi Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 808-486-6000
        • Principal Investigator:
          • Jami A. Fukui
      • ‘Aiea, Hawaii, United States, 96701
        • Recruiting
        • Queen's Cancer Center - Pearlridge
        • Contact:
          • Site Public Contact
          • Phone Number: 808-487-7447
        • Principal Investigator:
          • Jami A. Fukui
      • ‘Aiea, Hawaii, United States, 96701
        • Recruiting
        • The Cancer Center of Hawaii-Pali Momi
        • Contact:
          • Site Public Contact
          • Phone Number: 808-678-9000
        • Principal Investigator:
          • Jami A. Fukui
      • ‘Ewa Beach, Hawaii, United States, 96706
        • Recruiting
        • The Queen's Medical Center - West Oahu
        • Contact:
        • Principal Investigator:
          • Jami A. Fukui
    • Idaho
      • Boise, Idaho, United States, 83706
        • Recruiting
        • Saint Alphonsus Cancer Care Center-Boise
        • Contact:
        • Principal Investigator:
          • Samir Narayan
      • Caldwell, Idaho, United States, 83605
        • Recruiting
        • Saint Alphonsus Cancer Care Center-Caldwell
        • Contact:
        • Principal Investigator:
          • Samir Narayan
      • Coeur d'Alene, Idaho, United States, 83814
        • Recruiting
        • Kootenai Health - Coeur d'Alene
        • Principal Investigator:
          • John M. Schallenkamp
        • Contact:
      • Nampa, Idaho, United States, 83687
        • Recruiting
        • Saint Alphonsus Cancer Care Center-Nampa
        • Contact:
        • Principal Investigator:
          • Samir Narayan
    • Illinois
      • Alton, Illinois, United States, 62002
        • Active, not recruiting
        • Alton Memorial Hospital
      • Aurora, Illinois, United States, 60506
        • Recruiting
        • Advocate Outpatient Center - Aurora
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Aurora, Illinois, United States, 60504
        • Suspended
        • Rush-Copley Medical Center
      • Barrington, Illinois, United States, 60010
        • Recruiting
        • Advocate Good Shepherd Hospital
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
          • Site Public Contact
          • Phone Number: 847-842-4847
      • Bloomington, Illinois, United States, 61704
        • Recruiting
        • Illinois CancerCare-Bloomington
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Bloomington, Illinois, United States, 61701
        • Recruiting
        • OSF Saint Joseph Medical Center
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Canton, Illinois, United States, 61520
        • Recruiting
        • Illinois CancerCare-Canton
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Carbondale, Illinois, United States, 62902
        • Recruiting
        • Memorial Hospital of Carbondale
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
      • Carterville, Illinois, United States, 62918
        • Recruiting
        • SIH Cancer Institute
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
      • Carthage, Illinois, United States, 62321
        • Recruiting
        • Illinois CancerCare-Carthage
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Centralia, Illinois, United States, 62801
        • Recruiting
        • Centralia Oncology Clinic
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
      • Centralia, Illinois, United States, 62801
        • Suspended
        • Saint Mary's Hospital
      • Chicago, Illinois, United States, 60637
        • Recruiting
        • University of Chicago Comprehensive Cancer Center
        • Principal Investigator:
          • Steven J. Chmura
        • Contact:
      • Chicago, Illinois, United States, 60611
        • Recruiting
        • Northwestern University
        • Contact:
        • Principal Investigator:
          • Eric D. Donnelly
      • Chicago, Illinois, United States, 60612
        • Recruiting
        • John H Stroger Jr Hospital of Cook County
        • Contact:
          • Site Public Contact
          • Phone Number: 312-864-5204
        • Principal Investigator:
          • Deimante M. Tamkus
      • Chicago, Illinois, United States, 60657
        • Recruiting
        • Advocate Illinois Masonic Medical Center
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
          • Site Public Contact
          • Phone Number: 773-296-5360
      • Chicago, Illinois, United States, 60612
        • Recruiting
        • Rush MD Anderson Cancer Center
        • Principal Investigator:
          • Thomas Kim
        • Contact:
      • Crystal Lake, Illinois, United States, 60014
        • Recruiting
        • AMG Crystal Lake - Oncology
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Danville, Illinois, United States, 61832
        • Recruiting
        • Carle at The Riverfront
        • Contact:
        • Principal Investigator:
          • Kalika P. Sarma
      • DeKalb, Illinois, United States, 60115
        • Recruiting
        • Northwestern Medicine Cancer Center Kishwaukee
        • Contact:
        • Principal Investigator:
          • Eric D. Donnelly
      • Decatur, Illinois, United States, 62526
        • Recruiting
        • Cancer Care Specialists of Illinois - Decatur
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
      • Decatur, Illinois, United States, 62526
        • Recruiting
        • Decatur Memorial Hospital
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
      • Downers Grove, Illinois, United States, 60515
        • Recruiting
        • Advocate Good Samaritan Hospital
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Effingham, Illinois, United States, 62401
        • Recruiting
        • Carle Physician Group-Effingham
        • Contact:
        • Principal Investigator:
          • Kalika P. Sarma
      • Effingham, Illinois, United States, 62401
        • Recruiting
        • Crossroads Cancer Center
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
      • Elgin, Illinois, United States, 60123
        • Recruiting
        • Advocate Sherman Hospital
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
          • Site Public Contact
          • Phone Number: 847-429-2907
      • Elmhurst, Illinois, United States, 60126
        • Recruiting
        • Elmhurst Memorial Hospital
        • Contact:
        • Principal Investigator:
          • Mansoina Baweja
      • Eureka, Illinois, United States, 61530
        • Recruiting
        • Illinois CancerCare-Eureka
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Galesburg, Illinois, United States, 61401
        • Recruiting
        • Illinois CancerCare-Galesburg
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Galesburg, Illinois, United States, 61401
        • Suspended
        • Western Illinois Cancer Treatment Center
      • Geneva, Illinois, United States, 60134
        • Recruiting
        • Northwestern Medicine Cancer Center Delnor
        • Contact:
        • Principal Investigator:
          • Eric D. Donnelly
      • Glenview, Illinois, United States, 60026
        • Recruiting
        • Northwestern Medicine Glenview Outpatient Center
        • Principal Investigator:
          • Eric D. Donnelly
        • Contact:
          • Site Public Contact
          • Phone Number: 312-695-1102
      • Grayslake, Illinois, United States, 60030
        • Recruiting
        • Northwestern Medicine Grayslake Outpatient Center
        • Principal Investigator:
          • Eric D. Donnelly
        • Contact:
          • Site Public Contact
          • Phone Number: 312-695-1102
      • Harvey, Illinois, United States, 60426
        • Recruiting
        • Ingalls Memorial Hospital
        • Contact:
        • Principal Investigator:
          • Ivy Abraham
      • Hazel Crest, Illinois, United States, 60429
        • Recruiting
        • Advocate South Suburban Hospital
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
          • Site Public Contact
          • Phone Number: 708-799-9995
      • Kewanee, Illinois, United States, 61443
        • Recruiting
        • Illinois CancerCare-Kewanee Clinic
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Lake Forest, Illinois, United States, 60045
        • Recruiting
        • Northwestern Medicine Lake Forest Hospital
        • Contact:
        • Principal Investigator:
          • Eric D. Donnelly
      • Libertyville, Illinois, United States, 60048
        • Recruiting
        • AMG Libertyville - Oncology
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Libertyville, Illinois, United States, 60048
        • Recruiting
        • Condell Memorial Hospital
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Macomb, Illinois, United States, 61455
        • Recruiting
        • Illinois CancerCare-Macomb
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Mattoon, Illinois, United States, 61938
        • Recruiting
        • Carle Physician Group-Mattoon/Charleston
        • Contact:
        • Principal Investigator:
          • Kalika P. Sarma
      • Maywood, Illinois, United States, 60153
        • Recruiting
        • Loyola University Medical Center
        • Principal Investigator:
          • William Small
        • Contact:
          • Site Public Contact
          • Phone Number: 708-226-4357
      • Naperville, Illinois, United States, 60540
        • Recruiting
        • Edward Hospital/Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 630-646-6075
        • Principal Investigator:
          • Mansoina Baweja
      • New Lenox, Illinois, United States, 60451
        • Recruiting
        • UC Comprehensive Cancer Center at Silver Cross
        • Principal Investigator:
          • Steven J. Chmura
        • Contact:
      • Normal, Illinois, United States, 61761
        • Recruiting
        • Carle BroMenn Medical Center
        • Contact:
        • Principal Investigator:
          • Kalika P. Sarma
      • Normal, Illinois, United States, 61761
        • Recruiting
        • Carle Cancer Institute Normal
        • Contact:
        • Principal Investigator:
          • Kalika P. Sarma
      • O'Fallon, Illinois, United States, 62269
        • Recruiting
        • Cancer Care Center of O'Fallon
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
      • O'Fallon, Illinois, United States, 62269
        • Recruiting
        • HSHS Saint Elizabeth's Hospital
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
      • Oak Lawn, Illinois, United States, 60453-2699
        • Recruiting
        • Advocate Christ Medical Center
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
          • Site Public Contact
          • Phone Number: 800-323-8622
      • Orland Park, Illinois, United States, 60462
        • Recruiting
        • University of Chicago Medicine-Orland Park
        • Principal Investigator:
          • Steven J. Chmura
        • Contact:
      • Orland Park, Illinois, United States, 60462
      • Ottawa, Illinois, United States, 61350
        • Recruiting
        • Illinois CancerCare-Ottawa Clinic
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Palos Heights, Illinois, United States, 60463
        • Recruiting
        • Advocate High Tech Medical Park
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Park Ridge, Illinois, United States, 60068
        • Recruiting
        • Advocate Lutheran General Hospital
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
          • Site Public Contact
          • Phone Number: 847-384-3621
      • Pekin, Illinois, United States, 61554
        • Recruiting
        • Illinois CancerCare-Pekin
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Peoria, Illinois, United States, 61615
        • Recruiting
        • Illinois CancerCare-Peoria
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Peoria, Illinois, United States, 61615
        • Recruiting
        • OSF Saint Francis Radiation Oncology at Peoria Cancer Center
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Peoria, Illinois, United States, 61636
        • Recruiting
        • Methodist Medical Center of Illinois
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Peoria, Illinois, United States, 61637
        • Recruiting
        • OSF Saint Francis Medical Center
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Peru, Illinois, United States, 61354
        • Recruiting
        • Illinois CancerCare-Peru
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Plainfield, Illinois, United States, 60585
        • Recruiting
        • Edward Hospital/Cancer Center?Plainfield
        • Contact:
        • Principal Investigator:
          • Mansoina Baweja
      • Princeton, Illinois, United States, 61356
        • Recruiting
        • Illinois CancerCare-Princeton
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Rockford, Illinois, United States, 61114
        • Recruiting
        • UW Health Carbone Cancer Center Rockford
        • Contact:
        • Principal Investigator:
          • Fahrettin Covut
      • Shiloh, Illinois, United States, 62269
        • Active, not recruiting
        • Memorial Hospital East
      • Urbana, Illinois, United States, 61801
        • Recruiting
        • Carle Cancer Center
        • Contact:
        • Principal Investigator:
          • Kalika P. Sarma
      • Urbana, Illinois, United States, 61801
        • Recruiting
        • The Carle Foundation Hospital
        • Contact:
        • Principal Investigator:
          • Kalika P. Sarma
      • Warrenville, Illinois, United States, 60555
        • Recruiting
        • Northwestern Medicine Cancer Center Warrenville
        • Contact:
        • Principal Investigator:
          • Eric D. Donnelly
      • Washington, Illinois, United States, 61571
        • Recruiting
        • Illinois CancerCare - Washington
        • Contact:
        • Principal Investigator:
          • Bryan A. Faller
      • Zion, Illinois, United States, 60099
        • Recruiting
        • Midwestern Regional Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 844-793-0745
        • Principal Investigator:
          • Karan K. Shah
    • Indiana
      • Avon, Indiana, United States, 46123
        • Suspended
        • IU Health West Hospital
      • Carmel, Indiana, United States, 46032
        • Suspended
        • IU Health North Hospital
      • Crown Point, Indiana, United States, 46307
        • Recruiting
        • Northwest Cancer Center - Main Campus
        • Contact:
          • Site Public Contact
          • Phone Number: 219-310-2550
        • Principal Investigator:
          • Kalika P. Sarma
      • Crown Point, Indiana, United States, 46307
        • Recruiting
        • UChicago Medicine Northwest Indiana
        • Principal Investigator:
          • Steven J. Chmura
        • Contact:
      • Dyer, Indiana, United States, 46311
        • Recruiting
        • Northwest Oncology LLC
        • Contact:
          • Site Public Contact
          • Phone Number: 219-924-8178
        • Principal Investigator:
          • Kalika P. Sarma
      • Hobart, Indiana, United States, 46342
        • Recruiting
        • Northwest Cancer Center - Hobart
        • Contact:
          • Site Public Contact
          • Phone Number: 219-947-1795
        • Principal Investigator:
          • Kalika P. Sarma
      • Hobart, Indiana, United States, 46342
        • Recruiting
        • Saint Mary Medical Center
        • Principal Investigator:
          • Kalika P. Sarma
        • Contact:
      • Indianapolis, Indiana, United States, 46202
        • Recruiting
        • Indiana University/Melvin and Bren Simon Cancer Center
        • Principal Investigator:
          • Naoyuki G. Saito
        • Contact:
      • Indianapolis, Indiana, United States, 46237
        • Recruiting
        • Franciscan Health Indianapolis
        • Principal Investigator:
          • Sandeep R. Bhave
        • Contact:
          • Site Public Contact
          • Phone Number: 317-528-7060
      • Indianapolis, Indiana, United States, 46202
        • Suspended
        • IU Health Methodist Hospital
      • Mooresville, Indiana, United States, 46158
        • Recruiting
        • Franciscan Health Mooresville
        • Principal Investigator:
          • Sandeep R. Bhave
        • Contact:
          • Site Public Contact
          • Phone Number: 317-834-3603
      • Munster, Indiana, United States, 46321
        • Recruiting
        • The Community Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 219-836-3349
        • Principal Investigator:
          • Kalika P. Sarma
      • Munster, Indiana, United States, 46321
        • Recruiting
        • Women's Diagnostic Center - Munster
        • Contact:
        • Principal Investigator:
          • Kalika P. Sarma
      • Richmond, Indiana, United States, 47374
        • Recruiting
        • Reid Health
        • Contact:
        • Principal Investigator:
          • Howard M. Gross
      • Valparaiso, Indiana, United States, 46383
        • Recruiting
        • Northwest Cancer Center - Valparaiso
        • Principal Investigator:
          • Kalika P. Sarma
        • Contact:
    • Iowa
      • Ames, Iowa, United States, 50010
        • Recruiting
        • Mary Greeley Medical Center
        • Principal Investigator:
          • Joseph J. Merchant
        • Contact:
          • Site Public Contact
          • Phone Number: 515-956-4132
      • Ames, Iowa, United States, 50010
        • Recruiting
        • McFarland Clinic - Ames
        • Principal Investigator:
          • Joseph J. Merchant
        • Contact:
      • Ankeny, Iowa, United States, 50023
        • Recruiting
        • UI Health Care Mission Cancer and Blood - Ankeny Clinic
        • Contact:
          • Site Public Contact
          • Phone Number: 515-241-3305
        • Principal Investigator:
          • Richard L. Deming
      • Cedar Rapids, Iowa, United States, 52402
        • Recruiting
        • Saint Luke's Hospital
        • Contact:
        • Principal Investigator:
          • Candace R. Correa
      • Clive, Iowa, United States, 50325
        • Recruiting
        • Mercy Cancer Center-West Lakes
        • Contact:
          • Site Public Contact
          • Phone Number: 515-241-3305
        • Principal Investigator:
          • Richard L. Deming
      • Clive, Iowa, United States, 50325
        • Recruiting
        • UI Health Care Mission Cancer and Blood - West Des Moines Clinic
        • Contact:
          • Site Public Contact
          • Phone Number: 515-241-3305
        • Principal Investigator:
          • Seema Harichand-Herdt
      • Creston, Iowa, United States, 50801
        • Recruiting
        • Greater Regional Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 515-241-3305
        • Principal Investigator:
          • Richard L. Deming
      • Des Moines, Iowa, United States, 50314
        • Recruiting
        • Broadlawns Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 515-282-2200
        • Principal Investigator:
          • Seema Harichand-Herdt
      • Des Moines, Iowa, United States, 50314
        • Recruiting
        • Mercy Medical Center - Des Moines
        • Contact:
          • Site Public Contact
          • Phone Number: 515-241-3305
        • Principal Investigator:
          • Richard L. Deming
      • Des Moines, Iowa, United States, 50309
        • Recruiting
        • Iowa Methodist Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 515-241-6727
        • Principal Investigator:
          • Seema Harichand-Herdt
      • Des Moines, Iowa, United States, 50309
        • Recruiting
        • UI Health Care Mission Cancer and Blood - Des Moines Clinic
        • Contact:
          • Site Public Contact
          • Phone Number: 515-241-3305
        • Principal Investigator:
          • Seema Harichand-Herdt
      • Des Moines, Iowa, United States, 50314
        • Recruiting
        • UI Health Care Mission Cancer and Blood - Laurel Clinic
        • Contact:
          • Site Public Contact
          • Phone Number: 515-241-3305
        • Principal Investigator:
          • Seema Harichand-Herdt
      • Waukee, Iowa, United States, 50263
        • Recruiting
        • UI Health Care Mission Cancer and Blood - Waukee Clinic
        • Contact:
          • Site Public Contact
          • Phone Number: 515-241-3305
        • Principal Investigator:
          • Seema Harichand-Herdt
      • West Des Moines, Iowa, United States, 50266
        • Recruiting
        • Mercy Medical Center-West Lakes
        • Contact:
          • Site Public Contact
          • Phone Number: 515-241-3305
        • Principal Investigator:
          • Richard L. Deming
    • Kansas
      • Kansas City, Kansas, United States, 66160
        • Recruiting
        • University of Kansas Cancer Center
        • Contact:
        • Principal Investigator:
          • Julia R. White
      • Olathe, Kansas, United States, 66061
        • Recruiting
        • The University of Kansas Cancer Center - Olathe
        • Contact:
        • Principal Investigator:
          • Julia R. White
      • Overland Park, Kansas, United States, 66211
        • Recruiting
        • University of Kansas Hospital-Indian Creek Campus
        • Contact:
        • Principal Investigator:
          • Julia R. White
      • Overland Park, Kansas, United States, 66210
        • Recruiting
        • University of Kansas Cancer Center-Overland Park
        • Contact:
        • Principal Investigator:
          • Julia R. White
      • Salina, Kansas, United States, 67401
        • Recruiting
        • Cancer Center of Kansas - Salina
        • Contact:
        • Principal Investigator:
          • Dennis F. Moore
      • Salina, Kansas, United States, 67401
        • Recruiting
        • Salina Regional Health Center
        • Contact:
        • Principal Investigator:
          • Julia R. White
      • Topeka, Kansas, United States, 66606
        • Recruiting
        • University of Kansas Health System Saint Francis Campus
        • Contact:
          • Site Public Contact
          • Phone Number: 785-295-8000
        • Principal Investigator:
          • Julia R. White
      • Westwood, Kansas, United States, 66205
        • Recruiting
        • University of Kansas Hospital-Westwood Cancer Center
        • Contact:
        • Principal Investigator:
          • Julia R. White
      • Wichita, Kansas, United States, 67208
        • Recruiting
        • Cancer Center of Kansas-Wichita Medical Arts Tower
        • Contact:
        • Principal Investigator:
          • Dennis F. Moore
      • Wichita, Kansas, United States, 67214
        • Recruiting
        • Ascension Via Christi Hospitals Wichita
        • Contact:
        • Principal Investigator:
          • Dennis F. Moore
      • Wichita, Kansas, United States, 67214
        • Recruiting
        • Cancer Center of Kansas - Wichita
        • Contact:
        • Principal Investigator:
          • Dennis F. Moore
    • Kentucky
      • Lexington, Kentucky, United States, 40536
        • Recruiting
        • University of Kentucky/Markey Cancer Center
        • Principal Investigator:
          • Mark E. Bernard
        • Contact:
          • Site Public Contact
          • Phone Number: 859-257-3379
      • Lexington, Kentucky, United States, 40509
      • Lexington, Kentucky, United States, 40504
      • Lexington, Kentucky, United States, 40504
    • Louisiana
      • Covington, Louisiana, United States, 70433
        • Active, not recruiting
        • Ochsner Hematology Oncology North Shore - Covington (West Region)
      • New Orleans, Louisiana, United States, 70121
        • Recruiting
        • Ochsner Medical Center Jefferson
        • Principal Investigator:
          • Angela H. Wortham
        • Contact:
      • New Orleans, Louisiana, United States, 70112
        • Recruiting
        • University Medical Center New Orleans
        • Contact:
        • Principal Investigator:
          • Augusto C. Ochoa
      • New Orleans, Louisiana, United States, 70112
        • Recruiting
        • Louisiana State University Health Science Center
        • Contact:
        • Principal Investigator:
          • Augusto C. Ochoa
      • New Orleans, Louisiana, United States, 70112
        • Suspended
        • Tulane University School of Medicine
      • Shreveport, Louisiana, United States, 71103
        • Recruiting
        • LSU Health Sciences Center at Shreveport
        • Contact:
        • Principal Investigator:
          • Gary V. Burton
      • Shreveport, Louisiana, United States, 71106
        • Recruiting
        • Ochsner LSU Health - Cancer Treatment Center
        • Principal Investigator:
          • Gary V. Burton
        • Contact:
          • Site Public Contact
          • Phone Number: 318-813-1406
    • Maine
      • Brewer, Maine, United States, 04412
        • Recruiting
        • Lafayette Family Cancer Center-EMMC
        • Principal Investigator:
          • Sarah J. Sinclair
        • Contact:
          • Site Public Contact
          • Phone Number: 800-987-3005
    • Maryland
      • Baltimore, Maryland, United States, 21204
        • Recruiting
        • Greater Baltimore Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 443-849-3706
        • Principal Investigator:
          • Kruti Patel
      • Baltimore, Maryland, United States, 21215
        • Active, not recruiting
        • Sinai Hospital of Baltimore
      • Baltimore, Maryland, United States, 21229
        • Recruiting
        • Saint Agnes Hospital
        • Principal Investigator:
          • Richard S. Hudes
        • Contact:
          • Site Public Contact
          • Phone Number: 410-368-2910
      • Baltimore, Maryland, United States, 21237
        • Recruiting
        • MedStar Franklin Square Medical Center/Weinberg Cancer Institute
        • Principal Investigator:
          • Paul B. Fowler
        • Contact:
          • Site Public Contact
          • Phone Number: 443-777-7364
      • Baltimore, Maryland, United States, 21201
        • Recruiting
        • University of Maryland/Greenebaum Cancer Center
        • Principal Investigator:
          • Sarah A. Mcavoy
        • Contact:
          • Site Public Contact
          • Phone Number: 800-888-8823
      • Baltimore, Maryland, United States, 21239
        • Recruiting
        • MedStar Good Samaritan Hospital
        • Contact:
        • Principal Investigator:
          • Paul B. Fowler
      • Bel Air, Maryland, United States, 21014
        • Recruiting
        • UM Upper Chesapeake Medical Center
        • Principal Investigator:
          • Kamila Nowak Choi
        • Contact:
          • Site Public Contact
          • Phone Number: 443-643-3010
      • Bel Air, Maryland, United States, 21015
        • Recruiting
        • MedStar Health Bel Air Medical Campus
        • Principal Investigator:
          • Paul B. Fowler
        • Contact:
      • Columbia, Maryland, United States, 21044
        • Recruiting
        • Central Maryland Radiation Oncology in Howard County
        • Principal Investigator:
          • Sarah A. Mcavoy
        • Contact:
          • Site Public Contact
          • Phone Number: 443-546-1300
      • Easton, Maryland, United States, 21601
        • Recruiting
        • University of Maryland Shore Medical Center at Easton
        • Principal Investigator:
          • Sarah A. Mcavoy
        • Contact:
      • Glen Burnie, Maryland, United States, 21061
        • Recruiting
        • UM Baltimore Washington Medical Center/Tate Cancer Center
        • Principal Investigator:
          • Sarah A. Mcavoy
        • Contact:
          • Site Public Contact
          • Phone Number: 410-553-8100
      • Largo, Maryland, United States, 20774
        • Recruiting
        • Kaiser Permanente - Largo Medical Center
        • Principal Investigator:
          • James Liu
        • Contact:
      • Largo, Maryland, United States, 20774
        • Recruiting
        • UM Capital Region Medical Center
        • Principal Investigator:
          • Sarah A. Mcavoy
        • Contact:
      • Lutherville, Maryland, United States, 21093
        • Recruiting
        • Kaiser Permanente Lutherville - Timonium Medical Center
        • Principal Investigator:
          • James Liu
        • Contact:
      • Ocean Pines, Maryland, United States, 21811
        • Recruiting
        • TidalHealth Richard A Henson Cancer Institute
        • Contact:
        • Principal Investigator:
          • David McDermott
      • Salisbury, Maryland, United States, 21801
        • Recruiting
        • TidalHealth Peninsula Regional
        • Contact:
        • Principal Investigator:
          • David McDermott
      • Towson, Maryland, United States, 21204
        • Recruiting
        • UM Saint Joseph Medical Center
        • Principal Investigator:
          • Sarah A. Mcavoy
        • Contact:
    • Massachusetts
      • Boston, Massachusetts, United States, 02118
        • Suspended
        • Boston Medical Center
      • Lowell, Massachusetts, United States, 01854
        • Active, not recruiting
        • Lowell General Hospital
    • Michigan
      • Ann Arbor, Michigan, United States, 48109
        • Recruiting
        • University of Michigan Rogel Cancer Center
        • Principal Investigator:
          • Lori J. Pierce
        • Contact:
      • Ann Arbor, Michigan, United States, 48106
        • Recruiting
        • Trinity Health Saint Joseph Mercy Hospital Ann Arbor
        • Contact:
        • Principal Investigator:
          • Samir Narayan
      • Battle Creek, Michigan, United States, 49017
        • Recruiting
        • Bronson Battle Creek
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Bay City, Michigan, United States, 48706
        • Recruiting
        • McLaren Cancer Institute-Bay City
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Brighton, Michigan, United States, 48114
        • Recruiting
        • Trinity Health IHA Medical Group Hematology Oncology - Brighton
        • Contact:
        • Principal Investigator:
          • Samir Narayan
      • Brighton, Michigan, United States, 48116
        • Recruiting
        • University of Michigan - Brighton Center for Specialty Care
        • Contact:
          • Site Public Contact
          • Phone Number: 800-865-1125
        • Principal Investigator:
          • Lori J. Pierce
      • Brighton, Michigan, United States, 48114
      • Brownstown, Michigan, United States, 48183
        • Recruiting
        • Henry Ford Cancer Institute-Downriver
        • Contact:
        • Principal Investigator:
          • Eleanor M. Walker
      • Canton, Michigan, United States, 48188
        • Recruiting
        • Trinity Health IHA Medical Group Hematology Oncology - Canton
        • Contact:
        • Principal Investigator:
          • Samir Narayan
      • Canton, Michigan, United States, 48188
      • Caro, Michigan, United States, 48723
        • Suspended
        • Caro Cancer Center
      • Chelsea, Michigan, United States, 48118
        • Recruiting
        • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
        • Contact:
        • Principal Investigator:
          • Samir Narayan
      • Chelsea, Michigan, United States, 48118
      • Clarkston, Michigan, United States, 48346
        • Recruiting
        • McLaren Cancer Institute-Clarkston
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Clarkston, Michigan, United States, 48346
        • Recruiting
        • Michigan Healthcare Professionals Clarkston
        • Principal Investigator:
          • Frank A. Vicini
        • Contact:
      • Clinton Township, Michigan, United States, 48038
        • Recruiting
        • Henry Ford Macomb Hospital-Clinton Township
        • Contact:
        • Principal Investigator:
          • Eleanor M. Walker
      • Dearborn, Michigan, United States, 48126
        • Recruiting
        • Henry Ford Medical Center-Fairlane
        • Contact:
        • Principal Investigator:
          • Eleanor M. Walker
      • Detroit, Michigan, United States, 48201
        • Recruiting
        • Wayne State University/Karmanos Cancer Institute
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Detroit, Michigan, United States, 48202
        • Recruiting
        • Henry Ford Hospital
        • Contact:
        • Principal Investigator:
          • Eleanor M. Walker
      • Detroit, Michigan, United States, 48236
        • Recruiting
        • Henry Ford Health Saint John Hospital
        • Principal Investigator:
          • Samir Narayan
        • Contact:
      • Farmington Hills, Michigan, United States, 48334
        • Recruiting
        • Weisberg Cancer Treatment Center
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Farmington Hills, Michigan, United States, 48334
        • Recruiting
        • Michigan Healthcare Professionals Farmington
        • Principal Investigator:
          • Frank A. Vicini
        • Contact:
      • Farmington Hills, Michigan, United States, 48336
        • Recruiting
        • Corewell Health Farmington Hills Hospital
        • Principal Investigator:
          • Peter Y. Chen
        • Contact:
          • Site Public Contact
          • Phone Number: 248-551-7695
      • Flint, Michigan, United States, 48503
        • Recruiting
        • Genesys Hurley Cancer Institute
        • Contact:
        • Principal Investigator:
          • Samir Narayan
      • Flint, Michigan, United States, 48503
        • Recruiting
        • Hurley Medical Center
        • Contact:
        • Principal Investigator:
          • Samir Narayan
      • Flint, Michigan, United States, 48532
        • Recruiting
        • McLaren Cancer Institute-Flint
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Grand Rapids, Michigan, United States, 49503
        • Recruiting
        • Trinity Health Grand Rapids Hospital
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Grand Rapids, Michigan, United States, 49503
        • Recruiting
        • Corewell Health Grand Rapids Hospitals - Butterworth Hospital
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Grand Rapids, Michigan, United States, 49503
        • Recruiting
        • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Jackson, Michigan, United States, 49201
        • Recruiting
        • Allegiance Health
        • Contact:
        • Principal Investigator:
          • Eleanor M. Walker
      • Kalamazoo, Michigan, United States, 49007
        • Recruiting
        • Bronson Methodist Hospital
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Kalamazoo, Michigan, United States, 49007
        • Recruiting
        • West Michigan Cancer Center
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Kalamazoo, Michigan, United States, 49048
        • Recruiting
        • Beacon Kalamazoo
        • Principal Investigator:
          • Kathleen Y. Butler
        • Contact:
          • Site Public Contact
          • Phone Number: 574-647-7370
      • Lansing, Michigan, United States, 48910
        • Recruiting
        • Karmanos Cancer Institute at McLaren Greater Lansing
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Lapeer, Michigan, United States, 48446
        • Recruiting
        • McLaren Cancer Institute-Lapeer Region
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Livonia, Michigan, United States, 48154
        • Recruiting
        • Trinity Health Saint Mary Mercy Livonia Hospital
        • Contact:
        • Principal Investigator:
          • Samir Narayan
      • Macomb, Michigan, United States, 48044
        • Recruiting
        • Michigan Healthcare Professionals Macomb
        • Principal Investigator:
          • Frank A. Vicini
        • Contact:
      • Madison Heights, Michigan, United States, 48071
        • Recruiting
        • Michigan Healthcare Professionals Madison Heights
        • Principal Investigator:
          • Frank A. Vicini
        • Contact:
      • Marlette, Michigan, United States, 48453
        • Suspended
        • Saint Mary's Oncology/Hematology Associates of Marlette
      • Mount Clemens, Michigan, United States, 48043
        • Recruiting
        • McLaren Cancer Institute-Macomb
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Mount Pleasant, Michigan, United States, 48858
        • Recruiting
        • McLaren Cancer Institute-Central Michigan
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Muskegon, Michigan, United States, 49444
        • Recruiting
        • Trinity Health Muskegon Hospital
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Niles, Michigan, United States, 49120
        • Recruiting
        • Corewell Health Lakeland Hospitals - Niles Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 616-391-1230
        • Principal Investigator:
          • Kathleen Y. Butler
      • Norton Shores, Michigan, United States, 49444
        • Recruiting
        • Cancer and Hematology Centers of Western Michigan - Norton Shores
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Novi, Michigan, United States, 48377
        • Recruiting
        • Henry Ford Medical Center-Columbus
        • Contact:
        • Principal Investigator:
          • Eleanor M. Walker
      • Petoskey, Michigan, United States, 49770
        • Recruiting
        • McLaren Cancer Institute-Northern Michigan
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Pontiac, Michigan, United States, 48341
        • Recruiting
        • Trinity Health Saint Joseph Mercy Oakland Hospital
        • Contact:
        • Principal Investigator:
          • Samir Narayan
      • Pontiac, Michigan, United States, 48341
        • Recruiting
        • Michigan Healthcare Professionals Pontiac
        • Principal Investigator:
          • Samir Narayan
        • Contact:
      • Port Huron, Michigan, United States, 48060
        • Recruiting
        • McLaren-Port Huron
        • Principal Investigator:
          • Brian K. Yeh
        • Contact:
      • Royal Oak, Michigan, United States, 48073
        • Recruiting
        • Corewell Health William Beaumont University Hospital
        • Principal Investigator:
          • Peter Y. Chen
        • Contact:
          • Site Public Contact
          • Phone Number: 248-551-7695
      • Saginaw, Michigan, United States, 48604
        • Suspended
        • Oncology Hematology Associates of Saginaw Valley PC
      • Saginaw, Michigan, United States, 48601
      • Saint Joseph, Michigan, United States, 49085
        • Recruiting
        • Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Saint Joseph, Michigan, United States, 49085
        • Recruiting
        • Corewell Health Lakeland Hospitals - Saint Joseph Hospital
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Tawas City, Michigan, United States, 48764
      • Traverse City, Michigan, United States, 49684
        • Recruiting
        • Munson Medical Center
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Troy, Michigan, United States, 48098
        • Recruiting
        • Michigan Healthcare Professionals Troy
        • Principal Investigator:
          • Frank A. Vicini
        • Contact:
      • Troy, Michigan, United States, 48085
        • Recruiting
        • Corewell Health Beaumont Troy Hospital
        • Principal Investigator:
          • Peter Y. Chen
        • Contact:
          • Site Public Contact
          • Phone Number: 248-551-7695
      • Warren, Michigan, United States, 48093
        • Recruiting
        • Henry Ford Health Warren Hospital
        • Principal Investigator:
          • Samir Narayan
        • Contact:
      • West Bloomfield, Michigan, United States, 48322
        • Recruiting
        • Henry Ford West Bloomfield Hospital
        • Contact:
        • Principal Investigator:
          • Eleanor M. Walker
      • West Branch, Michigan, United States, 48661
        • Suspended
        • Saint Mary's Oncology/Hematology Associates of West Branch
      • Wyandotte, Michigan, United States, 48192
        • Recruiting
        • Henry Ford Wyandotte Hospital
        • Contact:
        • Principal Investigator:
          • Eleanor M. Walker
      • Wyoming, Michigan, United States, 49519
        • Recruiting
        • University of Michigan Health - West
        • Contact:
        • Principal Investigator:
          • Kathleen Y. Butler
      • Ypsilanti, Michigan, United States, 48197
        • Recruiting
        • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
        • Contact:
        • Principal Investigator:
          • Samir Narayan
    • Minnesota
      • Albert Lea, Minnesota, United States, 56007
        • Recruiting
        • Mayo Clinic Health System in Albert Lea
        • Contact:
          • Site Public Contact
          • Phone Number: 855-776-0015
        • Principal Investigator:
          • Dean A. Shumway
      • Burnsville, Minnesota, United States, 55337
        • Recruiting
        • Minnesota Oncology - Burnsville
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Burnsville, Minnesota, United States, 55337
        • Suspended
        • Fairview Ridges Hospital
      • Coon Rapids, Minnesota, United States, 55433
        • Recruiting
        • Mercy Hospital
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Edina, Minnesota, United States, 55435
        • Recruiting
        • Fairview Southdale Hospital
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Fridley, Minnesota, United States, 55432
        • Active, not recruiting
        • Unity Hospital
      • Mankato, Minnesota, United States, 56001
        • Recruiting
        • Mayo Clinic Health Systems-Mankato
        • Contact:
          • Site Public Contact
          • Phone Number: 855-776-0015
        • Principal Investigator:
          • Dean A. Shumway
      • Maple Grove, Minnesota, United States, 55369
        • Recruiting
        • Fairview Clinics and Surgery Center Maple Grove
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Maplewood, Minnesota, United States, 55109
        • Recruiting
        • Minnesota Oncology Hematology PA-Maplewood
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Minneapolis, Minnesota, United States, 55407
        • Recruiting
        • Abbott-Northwestern Hospital
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Minneapolis, Minnesota, United States, 55454
        • Suspended
        • Health Partners Inc
      • Monticello, Minnesota, United States, 55362
        • Recruiting
        • Monticello Cancer Center
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Robbinsdale, Minnesota, United States, 55422
        • Recruiting
        • North Memorial Medical Health Center
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Rochester, Minnesota, United States, 55905
        • Recruiting
        • Mayo Clinic in Rochester
        • Contact:
          • Site Public Contact
          • Phone Number: 855-776-0015
        • Principal Investigator:
          • Dean A. Shumway
      • Saint Cloud, Minnesota, United States, 56303
        • Recruiting
        • Coborn Cancer Center at Saint Cloud Hospital
        • Contact:
        • Principal Investigator:
          • Donald J. Jurgens
      • Saint Louis Park, Minnesota, United States, 55416
        • Recruiting
        • Park Nicollet Clinic - Saint Louis Park
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Saint Paul, Minnesota, United States, 55101
        • Recruiting
        • Regions Hospital
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Saint Paul, Minnesota, United States, 55102
        • Recruiting
        • United Hospital
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Shakopee, Minnesota, United States, 55379
        • Recruiting
        • Saint Francis Regional Medical Center
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Stillwater, Minnesota, United States, 55082
        • Recruiting
        • Lakeview Hospital
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Waconia, Minnesota, United States, 55387
        • Recruiting
        • Ridgeview Medical Center
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Woodbury, Minnesota, United States, 55125
        • Recruiting
        • Minnesota Oncology Hematology PA-Woodbury
        • Contact:
        • Principal Investigator:
          • Yan Ji
    • Mississippi
      • Gulfport, Mississippi, United States, 39502
        • Recruiting
        • Gulfport Memorial Hospital
        • Contact:
        • Principal Investigator:
          • Augusto C. Ochoa
    • Missouri
      • Cape Girardeau, Missouri, United States, 63703
        • Recruiting
        • Saint Francis Medical Center
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
          • Site Public Contact
          • Phone Number: 573-334-2230
          • Email: sfmc@sfmc.net
      • City of Saint Peters, Missouri, United States, 63376
        • Active, not recruiting
        • Siteman Cancer Center at Saint Peters Hospital
      • Columbia, Missouri, United States, 65212
        • Recruiting
        • MU Health - University Hospital/Ellis Fischel Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 573-882-7440
        • Principal Investigator:
          • Gregory B. Biedermann
      • Creve Coeur, Missouri, United States, 63141
        • Active, not recruiting
        • Siteman Cancer Center at West County Hospital
      • Farmington, Missouri, United States, 63640
        • Recruiting
        • Parkland Health Center - Farmington
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
          • Site Public Contact
          • Phone Number: 314-996-5569
      • Jefferson City, Missouri, United States, 65109
        • Active, not recruiting
        • MU Health Care Goldschmidt Cancer Center
      • Joplin, Missouri, United States, 64804
        • Recruiting
        • Freeman Health System
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
      • Kansas City, Missouri, United States, 64154
        • Recruiting
        • University of Kansas Cancer Center - North
        • Contact:
        • Principal Investigator:
          • Julia R. White
      • Kansas City, Missouri, United States, 64116
        • Recruiting
        • University of Kansas Cancer Center - Briarcliff
        • Contact:
          • Site Public Contact
          • Phone Number: 913-588-3671
        • Principal Investigator:
          • Julia R. White
      • Lee's Summit, Missouri, United States, 64064
        • Recruiting
        • University of Kansas Cancer Center - Lee's Summit
        • Contact:
        • Principal Investigator:
          • Julia R. White
      • North Kansas City, Missouri, United States, 64116
        • Recruiting
        • University of Kansas Cancer Center at North Kansas City Hospital
        • Contact:
        • Principal Investigator:
          • Julia R. White
      • Rolla, Missouri, United States, 65401
        • Recruiting
        • Mercy Clinic-Rolla-Cancer and Hematology
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
          • Site Public Contact
          • Phone Number: 573-458-6379
      • Rolla, Missouri, United States, 65401
        • Recruiting
        • Phelps Health Delbert Day Cancer Institute
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
      • Saint Joseph, Missouri, United States, 64506
        • Recruiting
        • Heartland Regional Medical Center
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
      • Sainte Genevieve, Missouri, United States, 63670
        • Recruiting
        • Sainte Genevieve County Memorial Hospital
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
          • Site Public Contact
          • Phone Number: 314-996-5569
      • Springfield, Missouri, United States, 65804
        • Recruiting
        • Mercy Hospital Springfield
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
          • Site Public Contact
          • Phone Number: 417-269-4520
      • Springfield, Missouri, United States, 65807
        • Recruiting
        • CoxHealth South Hospital
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
          • Site Public Contact
          • Phone Number: 417-269-4520
      • St Louis, Missouri, United States, 63110
        • Active, not recruiting
        • Washington University School of Medicine
      • St Louis, Missouri, United States, 63128
        • Recruiting
        • Mercy Hospital South
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
      • St Louis, Missouri, United States, 63141
        • Recruiting
        • Mercy Hospital Saint Louis
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
          • Site Public Contact
          • Phone Number: 314-251-7066
      • St Louis, Missouri, United States, 63131
        • Recruiting
        • Missouri Baptist Medical Center
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
          • Site Public Contact
          • Phone Number: 314-996-5569
      • St Louis, Missouri, United States, 63129
        • Active, not recruiting
        • Siteman Cancer Center-South County
      • St Louis, Missouri, United States, 63136
        • Active, not recruiting
        • Siteman Cancer Center at Christian Hospital
      • Sullivan, Missouri, United States, 63080
        • Recruiting
        • Missouri Baptist Sullivan Hospital
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
          • Site Public Contact
          • Phone Number: 314-996-5569
      • Sunset Hills, Missouri, United States, 63127
        • Recruiting
        • BJC Outpatient Center at Sunset Hills
        • Principal Investigator:
          • Bryan A. Faller
        • Contact:
          • Site Public Contact
          • Phone Number: 314-996-5569
    • Montana
      • Billings, Montana, United States, 59101
        • Recruiting
        • Billings Clinic Cancer Center
        • Principal Investigator:
          • John M. Schallenkamp
        • Contact:
      • Bozeman, Montana, United States, 59715
        • Recruiting
        • Bozeman Health Deaconess Hospital
        • Principal Investigator:
          • John M. Schallenkamp
        • Contact:
      • Great Falls, Montana, United States, 59405
        • Recruiting
        • Benefis Sletten Cancer Institute
        • Principal Investigator:
          • John M. Schallenkamp
        • Contact:
      • Missoula, Montana, United States, 59804
        • Recruiting
        • Community Medical Center
        • Principal Investigator:
          • John M. Schallenkamp
        • Contact:
    • Nebraska
      • Bellevue, Nebraska, United States, 68123
        • Recruiting
        • Nebraska Medicine-Bellevue
        • Contact:
        • Principal Investigator:
          • Andrew O. Wahl
      • Kearney, Nebraska, United States, 68847
      • Lincoln, Nebraska, United States, 68516
        • Recruiting
        • Cancer Partners of Nebraska
        • Principal Investigator:
          • Mark J. Stavas
        • Contact:
      • Omaha, Nebraska, United States, 68198
        • Recruiting
        • University of Nebraska Medical Center
        • Contact:
        • Principal Investigator:
          • Andrew O. Wahl
      • Omaha, Nebraska, United States, 68118
        • Recruiting
        • Nebraska Medicine-Village Pointe
        • Contact:
          • Site Public Contact
          • Phone Number: 402-559-5600
        • Principal Investigator:
          • Andrew O. Wahl
    • Nevada
      • Henderson, Nevada, United States, 89052
        • Recruiting
        • OptumCare Cancer Care at Seven Hills
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Las Vegas, Nevada, United States, 89102
        • Recruiting
        • OptumCare Cancer Care at Charleston
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Las Vegas, Nevada, United States, 89106
        • Recruiting
        • Radiation Oncology Centers of Nevada Central
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Las Vegas, Nevada, United States, 89119
        • Recruiting
        • Radiation Oncology Centers of Nevada Southeast
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Las Vegas, Nevada, United States, 89128
        • Recruiting
        • OptumCare Cancer Care at MountainView
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Las Vegas, Nevada, United States, 89135
        • Recruiting
        • Alliance for Childhood Diseases/Cure 4 the Kids Foundation
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Las Vegas, Nevada, United States, 89144
        • Recruiting
        • Summerlin Hospital Medical Center
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Las Vegas, Nevada, United States, 89148
        • Recruiting
        • Comprehensive Cancer Centers of Nevada
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Las Vegas, Nevada, United States, 89148
        • Recruiting
        • OptumCare Cancer Care at Fort Apache
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Las Vegas, Nevada, United States, 89169
        • Recruiting
        • Comprehensive Cancer Centers of Nevada - Central Valley
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
      • Reno, Nevada, United States, 89502
        • Recruiting
        • Renown Regional Medical Center
        • Contact:
        • Principal Investigator:
          • John A. Ellerton
    • New Hampshire
      • Concord, New Hampshire, United States, 03301
        • Active, not recruiting
        • New Hampshire Oncology Hematology PA-Concord
      • Lebanon, New Hampshire, United States, 03756
        • Recruiting
        • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
        • Principal Investigator:
          • Lesley A. Jarvis
        • Contact:
      • Manchester, New Hampshire, United States, 03103
        • Active, not recruiting
        • Solinsky Center for Cancer Care
    • New Jersey
      • Basking Ridge, New Jersey, United States, 07920
        • Recruiting
        • Memorial Sloan Kettering Basking Ridge
        • Principal Investigator:
          • Lior Z. Braunstein
        • Contact:
          • Site Public Contact
          • Phone Number: 212-639-7592
      • Middletown, New Jersey, United States, 07748
        • Recruiting
        • Memorial Sloan Kettering Monmouth
        • Principal Investigator:
          • Lior Z. Braunstein
        • Contact:
          • Site Public Contact
          • Phone Number: 212-639-7592
      • Montvale, New Jersey, United States, 07645
        • Recruiting
        • Memorial Sloan Kettering Bergen
        • Principal Investigator:
          • Lior Z. Braunstein
        • Contact:
          • Site Public Contact
          • Phone Number: 212-639-7592
      • Moorestown, New Jersey, United States, 08057
        • Active, not recruiting
        • Virtua Samson Cancer Center
      • Morristown, New Jersey, United States, 07960
        • Recruiting
        • Morristown Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 973-971-5900
        • Principal Investigator:
          • Joana S. Emmolo
      • Pennington, New Jersey, United States, 08534
        • Recruiting
        • Capital Health Medical Center-Hopewell
        • Contact:
        • Principal Investigator:
          • Nikhil Thaker
      • Pompton, New Jersey, United States, 07444
        • Recruiting
        • Chilton Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 973-971-5990
        • Principal Investigator:
          • Joana S. Emmolo
      • Summit, New Jersey, United States, 07902
        • Recruiting
        • Overlook Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 908-522-2043
        • Principal Investigator:
          • Joana S. Emmolo
      • Teaneck, New Jersey, United States, 07666
        • Recruiting
        • Holy Name Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 201-833-6312
        • Principal Investigator:
          • Raimonda Goldman
      • Voorhees Township, New Jersey, United States, 08043
        • Active, not recruiting
        • Virtua Voorhees
    • New Mexico
      • Albuquerque, New Mexico, United States, 87106
        • Recruiting
        • University of New Mexico Cancer Center
        • Contact:
        • Principal Investigator:
          • David Y. Lee
    • New York
      • Astoria, New York, United States, 11102
        • Recruiting
        • Mount Sinai Queens
        • Contact:
          • Site Public Contact
          • Phone Number: 212-824-7309
          • Email: CCTO@mssm.edu
        • Principal Investigator:
          • Manjeet Chadha
      • Bay Shore, New York, United States, 11706
        • Recruiting
        • Northwell Health Imbert Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 516-734-8896
        • Principal Investigator:
          • Brianna M. Jones
      • Binghamton, New York, United States, 13905
        • Recruiting
        • Lourdes Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 607-798-5230
        • Principal Investigator:
          • Beka Aroshidze
      • Brooklyn, New York, United States, 11220
        • Recruiting
        • NYU Langone Hospital - Brooklyn
        • Principal Investigator:
          • Naamit K. Gerber
        • Contact:
      • Buffalo, New York, United States, 14263
        • Recruiting
        • Roswell Park Cancer Institute
        • Contact:
        • Principal Investigator:
          • Simon D. Fung-Kee-Fung
      • Camillus, New York, United States, 13031
        • Recruiting
        • Hematology Oncology Associates of CNY at Camillus
        • Contact:
          • Site Public Contact
          • Phone Number: 315-472-7504
        • Principal Investigator:
          • Steven M. Duffy
      • Canandaigua, New York, United States, 14424
        • Recruiting
        • Sands Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 585-396-6161
        • Principal Investigator:
          • Kimberly Gergelis
      • Commack, New York, United States, 11725
        • Recruiting
        • Memorial Sloan Kettering Commack
        • Principal Investigator:
          • Lior Z. Braunstein
        • Contact:
          • Site Public Contact
          • Phone Number: 212-639-7592
      • Cooperstown, New York, United States, 13326
        • Recruiting
        • Mary Imogene Bassett Hospital
        • Principal Investigator:
          • Timothy P. Korytko
        • Contact:
      • East Hills, New York, United States, 11548
        • Recruiting
        • The Cancer Institute at Saint Francis Hospital
        • Contact:
        • Principal Investigator:
          • Rajasree Roy
      • East Syracuse, New York, United States, 13057
        • Recruiting
        • Hematology Oncology Associates of Central New York-East Syracuse
        • Contact:
          • Site Public Contact
          • Phone Number: 315-472-7504
        • Principal Investigator:
          • Steven M. Duffy
      • Elmira, New York, United States, 14905
        • Suspended
        • Arnot Ogden Medical Center/Falck Cancer Center
      • Glens Falls, New York, United States, 12801
        • Recruiting
        • Glens Falls Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 518-926-6700
        • Principal Investigator:
          • Puyao Li
      • Greenlawn, New York, United States, 11740
        • Recruiting
        • Northwell Health Cancer Institute at Huntington
        • Contact:
          • Site Public Contact
          • Phone Number: 516-734-8896
        • Principal Investigator:
          • Brianna M. Jones
      • Harrison, New York, United States, 10604
        • Recruiting
        • Memorial Sloan Kettering Westchester
        • Principal Investigator:
          • Lior Z. Braunstein
        • Contact:
          • Site Public Contact
          • Phone Number: 212-639-7592
      • Lake Success, New York, United States, 11042
        • Recruiting
        • Northwell Health/Center for Advanced Medicine
        • Contact:
          • Site Public Contact
          • Phone Number: 516-734-8896
        • Principal Investigator:
          • Brianna M. Jones
      • Mineola, New York, United States, 11501
        • Recruiting
        • NYU Langone Hospital - Long Island
        • Principal Investigator:
          • Naamit K. Gerber
        • Contact:
      • Mount Kisco, New York, United States, 10549
        • Recruiting
        • Northern Westchester Hospital
        • Contact:
        • Principal Investigator:
          • Brianna M. Jones
      • New York, New York, United States, 10065
        • Recruiting
        • Memorial Sloan Kettering Cancer Center
        • Principal Investigator:
          • Lior Z. Braunstein
        • Contact:
          • Site Public Contact
          • Phone Number: 212-639-7592
      • New York, New York, United States, 10011
        • Recruiting
        • Mount Sinai Chelsea
        • Contact:
          • Site Public Contact
          • Phone Number: 212-824-7309
          • Email: CCTO@mssm.edu
        • Principal Investigator:
          • Manjeet Chadha
      • New York, New York, United States, 10016
        • Recruiting
        • Laura and Isaac Perlmutter Cancer Center at NYU Langone
        • Principal Investigator:
          • Naamit K. Gerber
        • Contact:
      • New York, New York, United States, 10029
        • Recruiting
        • Mount Sinai Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 212-824-7309
          • Email: CCTO@mssm.edu
        • Principal Investigator:
          • Manjeet Chadha
      • New York, New York, United States, 10075
        • Recruiting
        • Lenox Hill Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 516-734-8896
        • Principal Investigator:
          • Brianna M. Jones
      • New York, New York, United States, 10065
        • Recruiting
        • Manhattan Eye Ear and Throat Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 212-434-4460
        • Principal Investigator:
          • Brianna M. Jones
      • New York, New York, United States, 10019
        • Recruiting
        • Mount Sinai West
        • Contact:
          • Site Public Contact
          • Phone Number: 212-824-7309
          • Email: CCTO@mssm.edu
        • Principal Investigator:
          • Manjeet Chadha
      • New York, New York, United States, 10003
        • Recruiting
        • Mount Sinai Union Square
        • Contact:
          • Site Public Contact
          • Phone Number: 212-824-7309
          • Email: CCTO@mssm.edu
        • Principal Investigator:
          • Manjeet Chadha
      • Oswego, New York, United States, 13126
        • Recruiting
        • Upstate Cancer Center at Oswego
        • Principal Investigator:
          • Anna Shapiro
        • Contact:
      • Oswego, New York, United States, 13126
        • Recruiting
        • Upstate Cancer Center Radiation Oncology at Oswego
        • Principal Investigator:
          • Anna Shapiro
        • Contact:
      • Rochester, New York, United States, 14642
        • Recruiting
        • University of Rochester
        • Contact:
          • Site Public Contact
          • Phone Number: 585-275-5830
        • Principal Investigator:
          • Kimberly Gergelis
      • Rochester, New York, United States, 14620
        • Recruiting
        • Highland Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 585-341-8113
        • Principal Investigator:
          • Kimberly Gergelis
      • Rochester, New York, United States, 14606
        • Recruiting
        • Wilmot Cancer Institute Radiation Oncology at Greece
        • Contact:
          • Site Public Contact
          • Phone Number: 585-758-7877
        • Principal Investigator:
          • Kimberly Gergelis
      • Rochester, New York, United States, 14623
        • Recruiting
        • Pluta Cancer Center
        • Contact:
        • Principal Investigator:
          • Kimberly Gergelis
      • Rockville Centre, New York, United States, 11570
        • Suspended
        • Mercy Hospital-Rockville Center
      • Sleepy Hollow, New York, United States, 10591
        • Recruiting
        • Phelps Memorial Hospital Center
        • Contact:
          • Site Public Contact
          • Phone Number: 914-366-1600
        • Principal Investigator:
          • Brianna M. Jones
      • Staten Island, New York, United States, 10305
        • Recruiting
        • Staten Island University Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 718-226-8888
        • Principal Investigator:
          • Brianna M. Jones
      • Stony Brook, New York, United States, 11794
        • Recruiting
        • Stony Brook University Medical Center
        • Principal Investigator:
          • Alexander M. Stessin
        • Contact:
          • Site Public Contact
          • Phone Number: 800-862-2215
      • Syracuse, New York, United States, 13210
        • Recruiting
        • State University of New York Upstate Medical University
        • Principal Investigator:
          • Anna Shapiro
        • Contact:
          • Site Public Contact
          • Phone Number: 315-464-5476
      • Syracuse, New York, United States, 13215
        • Recruiting
        • SUNY Upstate Medical Center-Community Campus
        • Principal Investigator:
          • Anna Shapiro
        • Contact:
          • Site Public Contact
          • Phone Number: 315-464-5476
      • Syracuse, New York, United States, 13210
        • Recruiting
        • Upstate Cancer Center at Hill Radiation Oncology
        • Principal Investigator:
          • Anna Shapiro
        • Contact:
      • The Bronx, New York, United States, 10461
        • Active, not recruiting
        • Montefiore Medical Center-Einstein Campus
      • The Bronx, New York, United States, 10461
        • Active, not recruiting
        • Montefiore Medical Center-Weiler Hospital
      • The Bronx, New York, United States, 10467
        • Active, not recruiting
        • Montefiore Medical Center - Moses Campus
      • Uniondale, New York, United States, 11553
        • Recruiting
        • Memorial Sloan Kettering Nassau
        • Principal Investigator:
          • Lior Z. Braunstein
        • Contact:
          • Site Public Contact
          • Phone Number: 212-639-7592
      • Verona, New York, United States, 13478
        • Recruiting
        • Upstate Cancer Center at Verona
        • Principal Investigator:
          • Anna Shapiro
        • Contact:
      • Webster, New York, United States, 14580
    • North Carolina
      • Albemarle, North Carolina, United States, 28002
        • Recruiting
        • Atrium Health Stanly/LCI-Albemarle
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 800-804-9376
      • Asheville, North Carolina, United States, 28801
      • Asheville, North Carolina, United States, 28816
      • Charlotte, North Carolina, United States, 28203
        • Recruiting
        • Carolinas Medical Center/Levine Cancer Institute
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 800-804-9376
      • Charlotte, North Carolina, United States, 28204
        • Recruiting
        • Novant Health Presbyterian Medical Center
        • Principal Investigator:
          • William B. Warlick
        • Contact:
      • Charlotte, North Carolina, United States, 28210
        • Recruiting
        • Atrium Health Pineville/LCI-Pineville
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 980-442-2000
      • Charlotte, North Carolina, United States, 28211
        • Recruiting
        • Levine Cancer Institute-SouthPark
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 980-442-2000
      • Charlotte, North Carolina, United States, 28262
        • Recruiting
        • Atrium Health University City/LCI-University
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 800-804-9376
      • Charlotte, North Carolina, United States, 28277
        • Recruiting
        • Levine Cancer Institute-Ballantyne
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 800-804-9376
      • Clemmons, North Carolina, United States, 27012
        • Recruiting
        • Wake Forest University at Clemmons
        • Contact:
          • Site Public Contact
          • Phone Number: 888-716-9259
        • Principal Investigator:
          • Doris R. Brown
      • Concord, North Carolina, United States, 28025
        • Recruiting
        • Atrium Health Cabarrus/LCI-Concord
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 800-804-9376
      • Forest City, North Carolina, United States, 28043
        • Recruiting
        • Levine Cancer Institute - Rutherford
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 800-804-9376
      • Greenville, North Carolina, United States, 27834
        • Recruiting
        • East Carolina University
        • Principal Investigator:
          • Frank A. Vicini
        • Contact:
      • Hendersonville, North Carolina, United States, 28791
      • High Point, North Carolina, United States, 27262
        • Recruiting
        • Hayworth Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 336-802-2500
        • Principal Investigator:
          • Doris R. Brown
      • Huntersville, North Carolina, United States, 28078
        • Recruiting
        • Novant Health Cancer Institute - Huntersville
        • Principal Investigator:
          • William B. Warlick
        • Contact:
      • Kernersville, North Carolina, United States, 27284
        • Recruiting
        • Novant Health Cancer Institute - Kernersville
        • Contact:
        • Principal Investigator:
          • Grant W. McKenzie
      • Matthews, North Carolina, United States, 28105
        • Recruiting
        • Novant Health Cancer Institute - Matthews
        • Principal Investigator:
          • William B. Warlick
        • Contact:
      • Matthews, North Carolina, United States, 28104
        • Recruiting
        • Levine Cancer Institute - Union West
        • Contact:
          • Site Public Contact
          • Phone Number: 980-442-0600
        • Principal Investigator:
          • Hadley J. Sharp
      • Matthews, North Carolina, United States, 28105
        • Recruiting
        • Matthews Radiation Oncology Center
        • Principal Investigator:
          • William B. Warlick
        • Contact:
      • Monroe, North Carolina, United States, 28112
        • Recruiting
        • Atrium Health Union/LCI-Union
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 980-442-2000
      • Mooresville, North Carolina, United States, 28117
        • Recruiting
        • Novant Health Cancer Institute - Mooresville
        • Principal Investigator:
          • William B. Warlick
        • Contact:
      • Mount Airy, North Carolina, United States, 27030
        • Recruiting
        • Novant Health Cancer Institute - Mount Airy
        • Contact:
        • Principal Investigator:
          • Grant W. McKenzie
      • New Bern, North Carolina, United States, 28561
        • Recruiting
        • CarolinaEast Medical Center
        • Principal Investigator:
          • Svetlana S. Kats
        • Contact:
      • North Wilkesboro, North Carolina, United States, 28659
        • Recruiting
        • Novant Health Cancer Institute - Wilkesboro
        • Contact:
        • Principal Investigator:
          • Grant W. McKenzie
      • Salisbury, North Carolina, United States, 28144
        • Recruiting
        • Rowan Regional Medical Center
        • Contact:
        • Principal Investigator:
          • William B. Warlick
      • Salisbury, North Carolina, United States, 28144
        • Recruiting
        • Novant Health Cancer Institute - Rowan
        • Principal Investigator:
          • William B. Warlick
        • Contact:
      • Shelby, North Carolina, United States, 28150
        • Recruiting
        • Atrium Health Cleveland/LCI-Cleveland
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 800-804-9376
      • Statesville, North Carolina, United States, 28625
        • Recruiting
        • Novant Health Cancer Institute - Statesville
        • Contact:
        • Principal Investigator:
          • Grant W. McKenzie
      • Thomasville, North Carolina, United States, 27360
        • Recruiting
        • Novant Health Cancer Institute - Thomasville
        • Contact:
        • Principal Investigator:
          • Grant W. McKenzie
      • Winston-Salem, North Carolina, United States, 27157
        • Recruiting
        • Wake Forest University Health Sciences
        • Contact:
          • Site Public Contact
          • Phone Number: 336-713-6771
        • Principal Investigator:
          • Doris R. Brown
      • Winston-Salem, North Carolina, United States, 27103
        • Recruiting
        • Novant Health Forsyth Medical Center
        • Contact:
        • Principal Investigator:
          • Grant W. McKenzie
    • North Dakota
      • Fargo, North Dakota, United States, 58122
        • Active, not recruiting
        • Sanford Broadway Medical Center
      • Fargo, North Dakota, United States, 58122
        • Active, not recruiting
        • Sanford Roger Maris Cancer Center
      • Grand Forks, North Dakota, United States, 58201
        • Recruiting
        • Altru Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 701-780-6520
        • Principal Investigator:
          • Grant R. Seeger
    • Ohio
      • Akron, Ohio, United States, 44307
        • Recruiting
        • Cleveland Clinic Akron General
        • Principal Investigator:
          • Ashok Ramalingam
        • Contact:
      • Akron, Ohio, United States, 44304
        • Recruiting
        • Summa Health System - Akron Campus
        • Principal Investigator:
          • Desiree E. Doncals
        • Contact:
      • Avon, Ohio, United States, 44011
        • Suspended
        • UH Seidman Cancer Center at UH Avon Health Center
      • Barberton, Ohio, United States, 44203
        • Recruiting
        • Summa Health System - Barberton Campus
        • Principal Investigator:
          • Desiree E. Doncals
        • Contact:
      • Beachwood, Ohio, United States, 44122
        • Recruiting
        • UHHS-Chagrin Highlands Medical Center
        • Contact:
        • Principal Investigator:
          • Janice Lyons
      • Beavercreek, Ohio, United States, 45431
        • Recruiting
        • Indu and Raj Soin Medical Center
        • Contact:
        • Principal Investigator:
          • Howard M. Gross
      • Canton, Ohio, United States, 44708
        • Recruiting
        • Cleveland Clinic Mercy Hospital
        • Principal Investigator:
          • Edward J. Walsh
        • Contact:
          • Site Public Contact
          • Phone Number: 888-293-4673
      • Canton, Ohio, United States, 44710
        • Recruiting
        • Aultman Health Foundation
        • Contact:
        • Principal Investigator:
          • Jessica L. Wobb
      • Centerville, Ohio, United States, 45459
        • Recruiting
        • Miami Valley Hospital South
        • Contact:
        • Principal Investigator:
          • Tarek M. Sabagh
      • Centerville, Ohio, United States, 45459
        • Suspended
        • Dayton Physicians LLC-Miami Valley South
      • Cincinnati, Ohio, United States, 45219
        • Recruiting
        • University of Cincinnati Cancer Center-UC Medical Center
        • Principal Investigator:
          • Teresa Meier
        • Contact:
      • Cleveland, Ohio, United States, 44106
        • Recruiting
        • Case Western Reserve University
        • Contact:
        • Principal Investigator:
          • Janice Lyons
      • Cleveland, Ohio, United States, 44109
        • Recruiting
        • MetroHealth Medical Center
        • Contact:
        • Principal Investigator:
          • Suzanne M. Russo
      • Cleveland, Ohio, United States, 44111
        • Recruiting
        • Cleveland Clinic Cancer Center/Fairview Hospital
        • Principal Investigator:
          • Saju A. Rajan
        • Contact:
      • Cleveland, Ohio, United States, 44195
        • Active, not recruiting
        • Cleveland Clinic Foundation
      • Columbus, Ohio, United States, 43213
        • Recruiting
        • Mount Carmel East Hospital
        • Contact:
        • Principal Investigator:
          • Aruna C. Gowda
      • Columbus, Ohio, United States, 43214
        • Recruiting
        • Riverside Methodist Hospital
        • Contact:
        • Principal Investigator:
          • Sana Rehman
      • Columbus, Ohio, United States, 43215
        • Recruiting
        • Grant Medical Center
        • Contact:
        • Principal Investigator:
          • Sana Rehman
      • Columbus, Ohio, United States, 43222
        • Recruiting
        • Mount Carmel Health Center West
        • Contact:
        • Principal Investigator:
          • Aruna C. Gowda
      • Columbus, Ohio, United States, 43228
        • Recruiting
        • Doctors Hospital
        • Contact:
        • Principal Investigator:
          • Sana Rehman
      • Columbus, Ohio, United States, 43210
        • Recruiting
        • Ohio State University Comprehensive Cancer Center
        • Contact:
        • Principal Investigator:
          • Sasha J. Beyer
      • Dayton, Ohio, United States, 45409
        • Recruiting
        • Miami Valley Hospital
        • Contact:
        • Principal Investigator:
          • Tarek M. Sabagh
      • Dayton, Ohio, United States, 45415
        • Recruiting
        • Miami Valley Hospital North
        • Contact:
        • Principal Investigator:
          • Tarek M. Sabagh
      • Dayton, Ohio, United States, 45409
        • Recruiting
        • Premier Blood and Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 937-276-8320
        • Principal Investigator:
          • Tarek M. Sabagh
      • Dayton, Ohio, United States, 45415
        • Recruiting
        • Dayton Physician LLC - Englewood
        • Contact:
        • Principal Investigator:
          • Howard M. Gross
      • Delaware, Ohio, United States, 43015
        • Recruiting
        • Delaware Health Center-Grady Cancer Center
        • Contact:
        • Principal Investigator:
          • Sana Rehman
      • Delaware, Ohio, United States, 43015
        • Recruiting
        • Grady Memorial Hospital
        • Contact:
        • Principal Investigator:
          • Sana Rehman
      • Dublin, Ohio, United States, 43016
        • Recruiting
        • Dublin Methodist Hospital
        • Contact:
        • Principal Investigator:
          • Sana Rehman
      • Findlay, Ohio, United States, 45840
        • Recruiting
        • Armes Family Cancer Center
        • Contact:
        • Principal Investigator:
          • Howard M. Gross
      • Findlay, Ohio, United States, 45840
        • Recruiting
        • Blanchard Valley Hospital
        • Contact:
        • Principal Investigator:
          • Howard M. Gross
      • Findlay, Ohio, United States, 45840
        • Suspended
        • Orion Cancer Care
      • Franklin, Ohio, United States, 45005-1066
        • Recruiting
        • Atrium Medical Center-Middletown Regional Hospital
        • Contact:
        • Principal Investigator:
          • Tarek M. Sabagh
      • Franklin, Ohio, United States, 45005
        • Recruiting
        • Dayton Physicians LLC-Atrium
        • Contact:
        • Principal Investigator:
          • Howard M. Gross
      • Greenville, Ohio, United States, 45331
        • Recruiting
        • Miami Valley Cancer Care and Infusion
        • Principal Investigator:
          • Tarek M. Sabagh
        • Contact:
          • Site Public Contact
          • Phone Number: 937-569-7515
      • Grove City, Ohio, United States, 43123
        • Recruiting
        • Mount Carmel Grove City Hospital
        • Contact:
        • Principal Investigator:
          • Aruna C. Gowda
      • Kettering, Ohio, United States, 45409
        • Recruiting
        • Greater Dayton Cancer Center
        • Contact:
        • Principal Investigator:
          • Howard M. Gross
      • Kettering, Ohio, United States, 45429
        • Recruiting
        • Kettering Medical Center
        • Contact:
        • Principal Investigator:
          • Howard M. Gross
      • Mansfield, Ohio, United States, 44903
        • Recruiting
        • OhioHealth Mansfield Hospital
        • Contact:
        • Principal Investigator:
          • Sana Rehman
      • Mansfield, Ohio, United States, 44906
        • Recruiting
        • Cleveland Clinic Cancer Center Mansfield
        • Principal Investigator:
          • Saju A. Rajan
        • Contact:
      • Marion, Ohio, United States, 43302
        • Recruiting
        • OhioHealth Marion General Hospital
        • Contact:
        • Principal Investigator:
          • Sana Rehman
      • Mayfield Heights, Ohio, United States, 44124
        • Recruiting
        • Hillcrest Hospital Cancer Center
        • Principal Investigator:
          • Saju A. Rajan
        • Contact:
      • Medina, Ohio, United States, 44256
        • Recruiting
        • Summa Health Medina Medical Center
        • Principal Investigator:
          • Desiree E. Doncals
        • Contact:
      • Mentor, Ohio, United States, 44060
        • Recruiting
        • UH Seidman Cancer Center at Lake Health Mentor Campus
        • Contact:
        • Principal Investigator:
          • Janice Lyons
      • Middleburg Heights, Ohio, United States, 44130
        • Recruiting
        • UH Seidman Cancer Center at Southwest General Hospital
        • Contact:
        • Principal Investigator:
          • Janice Lyons
      • New Albany, Ohio, United States, 43054
        • Recruiting
        • Mount Carmel New Albany Surgical Hospital
        • Contact:
        • Principal Investigator:
          • Aruna C. Gowda
      • Parma, Ohio, United States, 44129
        • Recruiting
        • University Hospitals Parma Medical Center
        • Contact:
        • Principal Investigator:
          • Janice Lyons
      • Ravenna, Ohio, United States, 44266
        • Recruiting
        • University Hospitals Portage Medical Center
        • Contact:
        • Principal Investigator:
          • Janice Lyons
      • Sandusky, Ohio, United States, 44870
        • Recruiting
        • UH Seidman Cancer Center at Firelands Regional Medical Center
        • Contact:
        • Principal Investigator:
          • Janice Lyons
      • Sandusky, Ohio, United States, 44870
        • Active, not recruiting
        • North Coast Cancer Care
      • Strongsville, Ohio, United States, 44136
        • Recruiting
        • Cleveland Clinic Cancer Center Strongsville
        • Principal Investigator:
          • Saju A. Rajan
        • Contact:
      • Sylvania, Ohio, United States, 43560
        • Recruiting
        • ProMedica Flower Hospital
        • Contact:
        • Principal Investigator:
          • Eric P. Kielhorn
      • Toledo, Ohio, United States, 43606
        • Recruiting
        • ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
        • Contact:
        • Principal Investigator:
          • Eric P. Kielhorn
      • Troy, Ohio, United States, 45373
        • Recruiting
        • Upper Valley Medical Center
        • Contact:
        • Principal Investigator:
          • Tarek M. Sabagh
      • Troy, Ohio, United States, 45373
        • Suspended
        • Dayton Physicians LLC - Troy
      • Warrensville Heights, Ohio, United States, 44122
        • Active, not recruiting
        • South Pointe Hospital
      • West Chester, Ohio, United States, 45069
        • Recruiting
        • University of Cincinnati Cancer Center-West Chester
        • Principal Investigator:
          • Teresa Meier
        • Contact:
      • Wooster, Ohio, United States, 44691
        • Recruiting
        • Cleveland Clinic Wooster Family Health and Surgery Center
        • Principal Investigator:
          • Saju A. Rajan
        • Contact:
      • Zanesville, Ohio, United States, 43701
        • Recruiting
        • Genesis Healthcare System Cancer Care Center
        • Contact:
        • Principal Investigator:
          • Aruna C. Gowda
    • Oklahoma
      • Oklahoma City, Oklahoma, United States, 73104
        • Recruiting
        • University of Oklahoma Health Sciences Center
        • Contact:
        • Principal Investigator:
          • Danushka Seneviratne
      • Oklahoma City, Oklahoma, United States, 73120
        • Recruiting
        • Mercy Hospital Oklahoma City
        • Principal Investigator:
          • Jay W. Carlson
        • Contact:
          • Site Public Contact
          • Phone Number: 405-752-3402
    • Oregon
      • Clackamas, Oregon, United States, 97015
        • Recruiting
        • Clackamas Radiation Oncology Center
        • Principal Investigator:
          • Dan S. Zuckerman
        • Contact:
      • Clackamas, Oregon, United States, 97015
        • Suspended
        • Providence Cancer Institute Clackamas Clinic
      • Gresham, Oregon, United States, 97030
        • Recruiting
        • Legacy Mount Hood Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 503-413-2150
        • Principal Investigator:
          • Andrew Y. Kee
      • Newberg, Oregon, United States, 97132
        • Recruiting
        • Providence Newberg Medical Center
        • Principal Investigator:
          • Dan S. Zuckerman
        • Contact:
      • Oregon City, Oregon, United States, 97045
        • Recruiting
        • Providence Willamette Falls Medical Center
        • Principal Investigator:
          • Dan S. Zuckerman
        • Contact:
      • Portland, Oregon, United States, 97213
        • Recruiting
        • Providence Portland Medical Center
        • Principal Investigator:
          • Dan S. Zuckerman
        • Contact:
      • Portland, Oregon, United States, 97225
        • Recruiting
        • Providence Saint Vincent Medical Center
        • Principal Investigator:
          • Dan S. Zuckerman
        • Contact:
      • Portland, Oregon, United States, 97210
        • Recruiting
        • Legacy Good Samaritan Hospital and Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 800-220-4937
          • Email: cancer@lhs.org
        • Principal Investigator:
          • Andrew Y. Kee
      • Portland, Oregon, United States, 97239
        • Active, not recruiting
        • Oregon Health and Science University
      • Portland, Oregon, United States, 97227
        • Active, not recruiting
        • Kaiser Permanente Northwest
      • Tualatin, Oregon, United States, 97062
        • Recruiting
        • Legacy Meridian Park Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 503-413-1742
        • Principal Investigator:
          • Andrew Y. Kee
    • Pennsylvania
      • Allentown, Pennsylvania, United States, 18104
        • Suspended
        • Saint Luke's Cancer Center - Allentown
      • Bethlehem, Pennsylvania, United States, 18015
        • Suspended
        • Saint Luke's University Hospital-Bethlehem Campus
      • Broomall, Pennsylvania, United States, 19008
        • Suspended
        • Crozer-Keystone Regional Cancer Center at Broomall
      • Chadds Ford, Pennsylvania, United States, 19317
        • Active, not recruiting
        • Christiana Care Health System-Concord Health Center
      • Chambersburg, Pennsylvania, United States, 17201
        • Recruiting
        • Chambersburg Hospital
        • Contact:
        • Principal Investigator:
          • Sherif F. Yacoub
      • Danville, Pennsylvania, United States, 17822
        • Recruiting
        • Geisinger Medical Center
        • Contact:
        • Principal Investigator:
          • Heath B. Mackley
      • Darby, Pennsylvania, United States, 19023-1291
        • Recruiting
        • Mercy Fitzgerald Hospital
        • Principal Investigator:
          • Pramila R. Anne
        • Contact:
          • Site Public Contact
          • Phone Number: 610-237-4982
      • Dunmore, Pennsylvania, United States, 18512
        • Recruiting
        • Northeast Radiation Oncology Center
        • Principal Investigator:
          • Pramila R. Anne
        • Contact:
          • Site Public Contact
          • Phone Number: 888-808-6762
      • East Norriton, Pennsylvania, United States, 19401
        • Recruiting
        • Fox Chase Cancer Center - East Norriton Hospital Outpatient Center
        • Contact:
        • Principal Investigator:
          • Rebecca M. Shulman
      • Easton, Pennsylvania, United States, 18045
        • Suspended
        • Saint Luke's Hospital-Anderson Campus
      • Ephrata, Pennsylvania, United States, 17522
        • Recruiting
        • Ephrata Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 717-721-4840
        • Principal Investigator:
          • Sherif F. Yacoub
      • Erie, Pennsylvania, United States, 16544
        • Recruiting
        • Saint Vincent Hospital
        • Principal Investigator:
          • Mark G. Trombetta
        • Contact:
          • Site Public Contact
          • Phone Number: 814-452-5000
      • Furlong, Pennsylvania, United States, 18925
        • Recruiting
        • Fox Chase Cancer Center Buckingham
        • Contact:
          • Site Public Contact
          • Phone Number: 215-794-2700
        • Principal Investigator:
          • Rebecca M. Shulman
      • Gettysburg, Pennsylvania, United States, 17325
        • Recruiting
        • Adams Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 877-441-7957
        • Principal Investigator:
          • Sherif F. Yacoub
      • Glen Mills, Pennsylvania, United States, 19342
        • Active, not recruiting
        • Crozer Regional Cancer Center at Brinton Lake
      • Hershey, Pennsylvania, United States, 17033-0850
        • Recruiting
        • Penn State Milton S Hershey Medical Center
        • Contact:
        • Principal Investigator:
          • Aruna Turaka
      • Jefferson Hills, Pennsylvania, United States, 15025
        • Recruiting
        • Jefferson Hospital
        • Principal Investigator:
          • Mark G. Trombetta
        • Contact:
      • Lebanon, Pennsylvania, United States, 17042
        • Recruiting
        • Sechler Family Cancer Center
        • Contact:
        • Principal Investigator:
          • Sherif F. Yacoub
      • Lewisburg, Pennsylvania, United States, 17837
        • Recruiting
        • Geisinger Medical Oncology-Lewisburg
        • Contact:
        • Principal Investigator:
          • Heath B. Mackley
      • Meadville, Pennsylvania, United States, 16335
        • Recruiting
        • Yolanda G Barco Oncology Institute
        • Principal Investigator:
          • Mark G. Trombetta
        • Contact:
      • Monroeville, Pennsylvania, United States, 15146
        • Recruiting
        • Forbes Hospital
        • Principal Investigator:
          • Mark G. Trombetta
        • Contact:
          • Site Public Contact
          • Phone Number: 412-858-7746
      • Natrona Heights, Pennsylvania, United States, 15065
        • Recruiting
        • Allegheny Valley Hospital
        • Principal Investigator:
          • Mark G. Trombetta
        • Contact:
      • Philadelphia, Pennsylvania, United States, 19107
        • Recruiting
        • Thomas Jefferson University Hospital
        • Principal Investigator:
          • Pramila R. Anne
        • Contact:
      • Philadelphia, Pennsylvania, United States, 19111
        • Recruiting
        • Fox Chase Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 215-728-4790
        • Principal Investigator:
          • Rebecca M. Shulman
      • Philadelphia, Pennsylvania, United States, 19140
        • Recruiting
        • Temple University Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 215-728-2983
        • Principal Investigator:
          • Rebecca M. Shulman
      • Philadelphia, Pennsylvania, United States, 19114
        • Recruiting
        • Jefferson Torresdale Hospital
        • Principal Investigator:
          • Pramila R. Anne
        • Contact:
      • Phoenixville, Pennsylvania, United States, 19460
        • Active, not recruiting
        • Reading Hospital McGlinn Cancer Institute at Phoenixville
      • Pittsburgh, Pennsylvania, United States, 15224
        • Recruiting
        • West Penn Hospital
        • Principal Investigator:
          • Mark G. Trombetta
        • Contact:
          • Site Public Contact
          • Phone Number: 412-578-5000
      • Pittsburgh, Pennsylvania, United States, 15212
        • Recruiting
        • Allegheny General Hospital
        • Principal Investigator:
          • Mark G. Trombetta
        • Contact:
          • Site Public Contact
          • Phone Number: 877-284-2000
      • Pottsville, Pennsylvania, United States, 17901
        • Recruiting
        • Geisinger Cancer Services-Pottsville
        • Contact:
        • Principal Investigator:
          • Heath B. Mackley
      • Quakertown, Pennsylvania, United States, 18951
        • Suspended
        • Saint Luke's Hospital-Quakertown Campus
      • Quakertown, Pennsylvania, United States, 18951
        • Suspended
        • Saint Luke's Hospital - Upper Bucks Campus
      • Sayre, Pennsylvania, United States, 18840
        • Recruiting
        • Guthrie Medical Group PC-Robert Packer Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 800-836-0388
        • Principal Investigator:
          • Joyson Poulose
      • Sellersville, Pennsylvania, United States, 18960
        • Active, not recruiting
        • Grand View Hospital
      • Stroudsburg, Pennsylvania, United States, 18360
        • Suspended
        • Saint Luke's Hospital - Monroe Campus
      • Wexford, Pennsylvania, United States, 15090
        • Recruiting
        • Wexford Health and Wellness Pavilion
        • Principal Investigator:
          • Mark G. Trombetta
        • Contact:
      • Wilkes-Barre, Pennsylvania, United States, 18711
        • Recruiting
        • Geisinger Wyoming Valley/Henry Cancer Center
        • Contact:
        • Principal Investigator:
          • Heath B. Mackley
      • Willow Grove, Pennsylvania, United States, 19090
        • Recruiting
        • Asplundh Cancer Pavilion
        • Principal Investigator:
          • Pramila R. Anne
        • Contact:
      • York, Pennsylvania, United States, 17403
        • Recruiting
        • WellSpan Health-York Cancer Center
        • Contact:
          • Site Public Contact
          • Phone Number: 877-441-7957
        • Principal Investigator:
          • Sherif F. Yacoub
      • York, Pennsylvania, United States, 17403
        • Recruiting
        • WellSpan Health-York Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 877-441-7957
        • Principal Investigator:
          • Sherif F. Yacoub
    • Rhode Island
      • Providence, Rhode Island, United States, 02903
        • Recruiting
        • Rhode Island Hospital
        • Principal Investigator:
          • Kara L. Leonard
        • Contact:
          • Site Public Contact
          • Phone Number: 401-444-1488
      • Providence, Rhode Island, United States, 02905
        • Recruiting
        • Women and Infants Hospital
        • Principal Investigator:
          • William M. Sikov
        • Contact:
          • Site Public Contact
          • Phone Number: 401-274-1122
      • Warwick, Rhode Island, United States, 02886
        • Recruiting
        • Kent Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 401-737-7010
        • Principal Investigator:
          • Micaela A. Weaver
      • Westerly, Rhode Island, United States, 02891
        • Recruiting
        • Smilow Cancer Hospital Care Center - Westerly
        • Principal Investigator:
          • Christin A. Knowlton
        • Contact:
    • South Carolina
      • Bluffton, South Carolina, United States, 29910
        • Recruiting
        • Saint Joseph's/Candler - Bluffton Campus
        • Contact:
        • Principal Investigator:
          • John L. Mikell
      • Charleston, South Carolina, United States, 29425
        • Recruiting
        • Medical University of South Carolina
        • Contact:
        • Principal Investigator:
          • Harriet B. Eldredge-Hindy
      • Florence, South Carolina, United States, 29506
        • Recruiting
        • McLeod Regional Medical Center
        • Contact:
        • Principal Investigator:
          • Rajesh Bajaj
      • Georgetown, South Carolina, United States, 29440
        • Recruiting
        • Tidelands Georgetown Memorial Hospital
        • Principal Investigator:
          • Harriet B. Eldredge-Hindy
        • Contact:
      • Hilton Head Island, South Carolina, United States, 29926
        • Recruiting
        • The Radiation Oncology Center-Hilton Head/Bluffton
        • Contact:
        • Principal Investigator:
          • John L. Mikell
      • Myrtle Beach, South Carolina, United States, 29577
        • Suspended
        • Carolina Regional Cancer Center
      • Okatie, South Carolina, United States, 29909
        • Recruiting
        • Beaufort Memorial/New River Cancer Center
        • Principal Investigator:
          • Harriet B. Eldredge-Hindy
        • Contact:
          • Site Public Contact
          • Phone Number: 843-273-7980
      • Rock Hill, South Carolina, United States, 29732
        • Recruiting
        • Levine Cancer Institute-Rock Hill
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 800-804-9376
      • Rock Hill, South Carolina, United States, 29730
        • Recruiting
        • Rock Hill Radiation Therapy Center
        • Principal Investigator:
          • Hadley J. Sharp
        • Contact:
          • Site Public Contact
          • Phone Number: 800-804-9376
    • South Dakota
      • Rapid City, South Dakota, United States, 57701
        • Active, not recruiting
        • Rapid City Regional Hospital
      • Sioux Falls, South Dakota, United States, 57104
        • Active, not recruiting
        • Sanford Cancer Center Oncology Clinic
      • Sioux Falls, South Dakota, United States, 57117-5134
        • Active, not recruiting
        • Sanford USD Medical Center - Sioux Falls
    • Tennessee
      • Knoxville, Tennessee, United States, 37920
        • Recruiting
        • University of Tennessee - Knoxville
        • Contact:
          • Site Public Contact
          • Phone Number: 865-544-9773
        • Principal Investigator:
          • Sarah Jenkins
      • Nashville, Tennessee, United States, 37232
        • Recruiting
        • Vanderbilt University/Ingram Cancer Center
        • Principal Investigator:
          • Anuradha B. Chakravarthy
        • Contact:
          • Site Public Contact
          • Phone Number: 800-811-8480
      • Nashville, Tennessee, United States, 37204
        • Recruiting
        • Vanderbilt Breast Center at One Hundred Oaks
        • Principal Investigator:
          • Anuradha B. Chakravarthy
        • Contact:
          • Site Public Contact
          • Phone Number: 800-811-8480
      • Nashville, Tennessee, United States, 37203
        • Recruiting
        • The Children's Hospital at TriStar Centennial
        • Principal Investigator:
          • Andrew S. Kennedy
        • Contact:
          • Site Public Contact
          • Phone Number: 615-342-1919
    • Texas
      • Abilene, Texas, United States, 79601
        • Active, not recruiting
        • Hendrick Medical Center
      • Baytown, Texas, United States, 77521
        • Recruiting
        • Houston Methodist San Jacinto Hospital
        • Contact:
        • Principal Investigator:
          • Sandra FINK Templeton
      • Conroe, Texas, United States, 77384
        • Recruiting
        • MD Anderson in The Woodlands
        • Principal Investigator:
          • Simona F. Shaitelman
        • Contact:
      • Cypress, Texas, United States, 77429
        • Recruiting
        • Houston Methodist Cypress Hospital
        • Contact:
        • Principal Investigator:
          • Sandra FINK Templeton
      • Fort Sam Houston, Texas, United States, 78234
        • Active, not recruiting
        • Brooke Army Medical Center
      • Galveston, Texas, United States, 77555-0565
        • Recruiting
        • University of Texas Medical Branch
        • Contact:
        • Principal Investigator:
          • Mediha Ahmad
      • Houston, Texas, United States, 77030
        • Recruiting
        • M D Anderson Cancer Center
        • Principal Investigator:
          • Simona F. Shaitelman
        • Contact:
      • Houston, Texas, United States, 77030
        • Recruiting
        • Houston Methodist Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 713-790-2700
        • Principal Investigator:
          • Sandra FINK Templeton
      • Houston, Texas, United States, 77070
        • Recruiting
        • Methodist Willowbrook Hospital
        • Contact:
        • Principal Investigator:
          • Sandra FINK Templeton
      • Houston, Texas, United States, 77094
        • Recruiting
        • Houston Methodist West Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 832-522-2873
        • Principal Investigator:
          • Sandra FINK Templeton
      • Houston, Texas, United States, 77079
        • Recruiting
        • MD Anderson West Houston
        • Principal Investigator:
          • Simona F. Shaitelman
        • Contact:
      • Laredo, Texas, United States, 78041
        • Suspended
        • Doctor's Hospital of Laredo
      • League City, Texas, United States, 77573
        • Recruiting
        • MD Anderson League City
        • Principal Investigator:
          • Simona F. Shaitelman
        • Contact:
      • Lubbock, Texas, United States, 79415
        • Recruiting
        • UMC Cancer Center / UMC Health System
        • Principal Investigator:
          • Karla A. Daniele
        • Contact:
          • Site Public Contact
          • Phone Number: 806-775-8590
      • Lubbock, Texas, United States, 79430
        • Recruiting
        • Texas Tech University Health Sciences Center-Lubbock
        • Principal Investigator:
          • Karla A. Daniele
        • Contact:
          • Site Public Contact
          • Phone Number: 806-775-8590
      • Nassau Bay, Texas, United States, 77058
        • Recruiting
        • Houston Methodist Saint John Hospital
        • Contact:
        • Principal Investigator:
          • Sandra FINK Templeton
      • San Antonio, Texas, United States, 78229
        • Active, not recruiting
        • University of Texas Health Science Center at San Antonio
      • Sugar Land, Texas, United States, 77479
        • Recruiting
        • Houston Methodist Sugar Land Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 281-242-2873
        • Principal Investigator:
          • Sandra FINK Templeton
      • Sugar Land, Texas, United States, 77478
        • Recruiting
        • MD Anderson in Sugar Land
        • Principal Investigator:
          • Simona F. Shaitelman
        • Contact:
      • The Woodlands, Texas, United States, 77385
        • Recruiting
        • Houston Methodist The Woodlands Hospital
        • Contact:
        • Principal Investigator:
          • Sandra FINK Templeton
    • Utah
      • American Fork, Utah, United States, 84003
        • Recruiting
        • American Fork Hospital / Huntsman Intermountain Cancer Center
        • Principal Investigator:
          • Dustin Boothe
        • Contact:
      • Cedar City, Utah, United States, 84720
        • Recruiting
        • Sandra L Maxwell Cancer Center
        • Contact:
        • Principal Investigator:
          • Dustin Boothe
      • Logan, Utah, United States, 84321
        • Recruiting
        • Logan Regional Hospital
        • Principal Investigator:
          • Dustin Boothe
        • Contact:
      • Murray, Utah, United States, 84107
        • Recruiting
        • Intermountain Medical Center
        • Principal Investigator:
          • Dustin Boothe
        • Contact:
      • Ogden, Utah, United States, 84403
        • Recruiting
        • McKay-Dee Hospital Center
        • Principal Investigator:
          • Dustin Boothe
        • Contact:
      • Provo, Utah, United States, 84604
        • Recruiting
        • Utah Valley Regional Medical Center
        • Principal Investigator:
          • Dustin Boothe
        • Contact:
      • Riverton, Utah, United States, 84065
        • Recruiting
        • Riverton Hospital
        • Principal Investigator:
          • Dustin Boothe
        • Contact:
      • Salt Lake City, Utah, United States, 84106
        • Recruiting
        • Utah Cancer Specialists-Salt Lake City
        • Contact:
        • Principal Investigator:
          • Dustin Boothe
      • Salt Lake City, Utah, United States, 84143
        • Recruiting
        • LDS Hospital
        • Principal Investigator:
          • Dustin Boothe
        • Contact:
      • St. George, Utah, United States, 84770
        • Recruiting
        • Saint George Regional Medical Center
        • Contact:
        • Principal Investigator:
          • Dustin Boothe
    • Vermont
      • Burlington, Vermont, United States, 05401
        • Recruiting
        • University of Vermont Medical Center
        • Contact:
          • Site Public Contact
          • Phone Number: 802-656-4101
          • Email: rpo@uvm.edu
        • Principal Investigator:
          • Puyao Li
      • Burlington, Vermont, United States, 05405
        • Recruiting
        • University of Vermont and State Agricultural College
        • Contact:
          • Site Public Contact
          • Phone Number: 802-656-8990
          • Email: rpo@uvm.edu
        • Principal Investigator:
          • Puyao Li
      • Saint Johnsbury, Vermont, United States, 05819
        • Recruiting
        • Dartmouth Cancer Center - North
        • Principal Investigator:
          • Lesley A. Jarvis
        • Contact:
    • Virginia
      • Mechanicsville, Virginia, United States, 23116
        • Recruiting
        • Bon Secours Memorial Regional Medical Center
        • Contact:
        • Principal Investigator:
          • William J. Irvin
      • Mechanicsville, Virginia, United States, 23116
        • Active, not recruiting
        • VCU Massey Cancer Center at Hanover Medical Park
      • Midlothian, Virginia, United States, 23114
        • Recruiting
        • Bon Secours Saint Francis Medical Center
        • Contact:
        • Principal Investigator:
          • William J. Irvin
      • Portsmouth, Virginia, United States, 23708-2197
        • Suspended
        • Naval Medical Center - Portsmouth
      • Richmond, Virginia, United States, 23226
        • Recruiting
        • Bon Secours Saint Mary's Hospital
        • Contact:
        • Principal Investigator:
          • William J. Irvin
      • Richmond, Virginia, United States, 23230
        • Recruiting
        • Bon Secours Cancer Institute at Reynolds Crossing
        • Contact:
        • Principal Investigator:
          • William J. Irvin
      • Richmond, Virginia, United States, 23235
        • Active, not recruiting
        • VCU Massey Cancer Center at Stony Point
      • Richmond, Virginia, United States, 23298
        • Active, not recruiting
        • VCU Massey Comprehensive Cancer Center
      • South Hill, Virginia, United States, 23970
        • Recruiting
        • VCU Community Memorial Health Center
        • Principal Investigator:
          • Todd C. Adams
        • Contact:
    • Washington
      • Bellingham, Washington, United States, 98225
        • Recruiting
        • PeaceHealth Saint Joseph Medical Center
        • Principal Investigator:
          • Dan S. Zuckerman
        • Contact:
      • Edmonds, Washington, United States, 98026
        • Recruiting
        • Swedish Cancer Institute-Edmonds
        • Principal Investigator:
          • Dan S. Zuckerman
        • Contact:
      • Issaquah, Washington, United States, 98029
        • Recruiting
        • Swedish Cancer Institute-Issaquah
        • Principal Investigator:
          • Dan S. Zuckerman
        • Contact:
      • Mount Vernon, Washington, United States, 98274
      • Seattle, Washington, United States, 98122-5711
        • Suspended
        • Swedish Medical Center-Cherry Hill
      • Seattle, Washington, United States, 98122
        • Recruiting
        • Swedish Medical Center-First Hill
        • Principal Investigator:
          • Dan S. Zuckerman
        • Contact:
      • Seattle, Washington, United States, 98107
        • Recruiting
        • Swedish Medical Center-Ballard Campus
        • Principal Investigator:
          • Dan S. Zuckerman
        • Contact:
      • Silverdale, Washington, United States, 98383
      • Vancouver, Washington, United States, 98686
        • Recruiting
        • Legacy Salmon Creek Hospital
        • Contact:
          • Site Public Contact
          • Phone Number: 503-413-2150
        • Principal Investigator:
          • Andrew Y. Kee
      • Vancouver, Washington, United States, 98684
        • Recruiting
        • Legacy Cancer Institute Medical Oncology and Day Treatment
        • Contact:
        • Principal Investigator:
          • Andrew Y. Kee
    • West Virginia
      • Huntington, West Virginia, United States, 25701
        • Recruiting
        • Edwards Comprehensive Cancer Center
        • Contact:
        • Principal Investigator:
          • Toni O. Pacioles
    • Wisconsin
      • Antigo, Wisconsin, United States, 54409
        • Recruiting
        • Langlade Hospital and Cancer Center
        • Contact:
        • Principal Investigator:
          • Andrew J. Huang
      • Appleton, Wisconsin, United States, 54911
        • Active, not recruiting
        • ThedaCare Regional Cancer Center
      • Burlington, Wisconsin, United States, 53105
        • Recruiting
        • Aurora Cancer Care-Southern Lakes VLCC
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Eau Claire, Wisconsin, United States, 54701
      • Eau Claire, Wisconsin, United States, 54701
        • Active, not recruiting
        • HSHS Sacred Heart Hospital
      • Fond du Lac, Wisconsin, United States, 54935
        • Suspended
        • Saint Agnes Hospital/Agnesian Cancer Center
      • Fond du Lac, Wisconsin, United States, 54937
        • Recruiting
        • Aurora Health Center-Fond du Lac
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Germantown, Wisconsin, United States, 53022
        • Recruiting
        • Aurora Health Care Germantown Health Center
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Grafton, Wisconsin, United States, 53024
        • Recruiting
        • Aurora Cancer Care-Grafton
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Green Bay, Wisconsin, United States, 54311
        • Recruiting
        • Aurora BayCare Medical Center
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Green Bay, Wisconsin, United States, 54301
        • Recruiting
        • Saint Vincent Hospital Cancer Center Green Bay
        • Principal Investigator:
          • Matthew L. Ryan
        • Contact:
      • Green Bay, Wisconsin, United States, 54303
        • Recruiting
        • Saint Vincent Hospital Cancer Center at Saint Mary's
        • Principal Investigator:
          • Matthew L. Ryan
        • Contact:
      • Johnson Creek, Wisconsin, United States, 53038
        • Recruiting
        • University of Wisconsin Carbone Cancer Center - Johnson Creek
        • Principal Investigator:
          • Bethany M. Anderson
        • Contact:
      • Kenosha, Wisconsin, United States, 53142
        • Recruiting
        • Aurora Cancer Care-Kenosha South
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • La Crosse, Wisconsin, United States, 54601
        • Recruiting
        • Mayo Clinic Health System-Franciscan Healthcare
        • Contact:
          • Site Public Contact
          • Phone Number: 855-776-0015
        • Principal Investigator:
          • Dean A. Shumway
      • Madison, Wisconsin, United States, 53792
        • Recruiting
        • University of Wisconsin Carbone Cancer Center - University Hospital
        • Principal Investigator:
          • Bethany M. Anderson
        • Contact:
      • Madison, Wisconsin, United States, 53718
        • Recruiting
        • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
        • Principal Investigator:
          • Bethany M. Anderson
        • Contact:
      • Marinette, Wisconsin, United States, 54143
        • Recruiting
        • Aurora Bay Area Medical Group-Marinette
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Marshfield, Wisconsin, United States, 54449
      • Medford, Wisconsin, United States, 54451
        • Recruiting
        • Aspirus Medford Hospital
        • Principal Investigator:
          • Andrew J. Huang
        • Contact:
      • Menomonee Falls, Wisconsin, United States, 53051
        • Recruiting
        • Froedtert Menomonee Falls Hospital
        • Principal Investigator:
          • Adam D. Currey
        • Contact:
          • Site Public Contact
          • Phone Number: 262-257-5100
      • Milwaukee, Wisconsin, United States, 53209
        • Recruiting
        • Aurora Cancer Care-Milwaukee
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Milwaukee, Wisconsin, United States, 53215
        • Recruiting
        • Aurora Saint Luke's Medical Center
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Milwaukee, Wisconsin, United States, 53226
        • Recruiting
        • Medical College of Wisconsin
        • Principal Investigator:
          • Adam D. Currey
        • Contact:
          • Site Public Contact
          • Phone Number: 414-805-3666
      • Milwaukee, Wisconsin, United States, 53233
        • Recruiting
        • Aurora Sinai Medical Center
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Minocqua, Wisconsin, United States, 54548
      • Mukwonago, Wisconsin, United States, 53149
        • Recruiting
        • ProHealth D N Greenwald Center
        • Contact:
        • Principal Investigator:
          • Timothy R. Wassenaar
      • New Richmond, Wisconsin, United States, 54017
        • Recruiting
        • Cancer Center of Western Wisconsin
        • Contact:
        • Principal Investigator:
          • Yan Ji
      • Oak Creek, Wisconsin, United States, 53154
        • Recruiting
        • Drexel Town Square Health Center
        • Principal Investigator:
          • Adam D. Currey
        • Contact:
          • Site Public Contact
          • Phone Number: 414-805-0505
      • Oconomowoc, Wisconsin, United States, 53066
        • Recruiting
        • ProHealth Oconomowoc Memorial Hospital
        • Principal Investigator:
          • Timothy R. Wassenaar
        • Contact:
          • Site Public Contact
          • Phone Number: 262-928-7878
      • Oshkosh, Wisconsin, United States, 54904
        • Recruiting
        • Vince Lombardi Cancer Clinic - Oshkosh
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Racine, Wisconsin, United States, 53406
        • Recruiting
        • Aurora Cancer Care-Racine
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Rhinelander, Wisconsin, United States, 54501
        • Recruiting
        • Aspirus Cancer Care - James Beck Cancer Center
        • Principal Investigator:
          • Andrew J. Huang
        • Contact:
      • Rice Lake, Wisconsin, United States, 54868
      • Sheboygan, Wisconsin, United States, 53081
        • Recruiting
        • Vince Lombardi Cancer Clinic-Sheboygan
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Sheboygan, Wisconsin, United States, 53081
        • Recruiting
        • Saint Vincent Hospital Cancer Center at Sheboygan
        • Principal Investigator:
          • Matthew L. Ryan
        • Contact:
      • Sheboygan, Wisconsin, United States, 53081
        • Recruiting
        • Sheboygan Physicians Group
        • Principal Investigator:
          • Matthew L. Ryan
        • Contact:
      • Stevens Point, Wisconsin, United States, 54482
      • Stevens Point, Wisconsin, United States, 54481
        • Recruiting
        • Aspirus Cancer Care - Stevens Point
        • Principal Investigator:
          • Andrew J. Huang
        • Contact:
      • Sturgeon Bay, Wisconsin, United States, 54235-1495
        • Recruiting
        • Saint Vincent Hospital Cancer Center at Sturgeon Bay
        • Principal Investigator:
          • Matthew L. Ryan
        • Contact:
      • Summit, Wisconsin, United States, 53066
        • Recruiting
        • Aurora Medical Center in Summit
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Two Rivers, Wisconsin, United States, 54241
        • Recruiting
        • Vince Lombardi Cancer Clinic-Two Rivers
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • Waukesha, Wisconsin, United States, 53188
        • Recruiting
        • UW Cancer Center at ProHealth Care
        • Principal Investigator:
          • Timothy R. Wassenaar
        • Contact:
      • Wausau, Wisconsin, United States, 54401
        • Recruiting
        • Aspirus Regional Cancer Center
        • Principal Investigator:
          • Andrew J. Huang
        • Contact:
          • Site Public Contact
          • Phone Number: 877-405-6866
      • Wauwatosa, Wisconsin, United States, 53226
        • Recruiting
        • Aurora Cancer Care-Milwaukee West
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • West Allis, Wisconsin, United States, 53227
        • Recruiting
        • Aurora West Allis Medical Center
        • Principal Investigator:
          • Ellen L. Ziaja
        • Contact:
      • West Bend, Wisconsin, United States, 53095
        • Recruiting
        • Froedtert West Bend Hospital/Kraemer Cancer Center
        • Principal Investigator:
          • Adam D. Currey
        • Contact:
          • Site Public Contact
          • Phone Number: 414-805-0505
      • Weston, Wisconsin, United States, 54476
      • Wisconsin Rapids, Wisconsin, United States, 54494
        • Recruiting
        • Aspirus Cancer Care - Wisconsin Rapids
        • Principal Investigator:
          • Andrew J. Huang
        • Contact:
          • Site Public Contact
          • Phone Number: 715-422-7718

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

50 years to 70 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • • The patient or a legally authorized representative must provide study-specific informed consent prior to pre-entry/Step 1 and, for patients treated in the U.S., authorization permitting release of personal health information.

    • The patient must have an ECOG performance status of 0 or 1.
    • The patient must have undergone a lumpectomy and the margins of the resected specimen or re-excision must be histologically free of invasive tumor and DCIS with no ink on tumor as determined by the local pathologist. If pathologic examination demonstrates tumor at the line of resection, additional excisions may be performed to obtain clear margins. (Patients with margins positive for LCIS are eligible without additional resection.)
    • The tumor must be unilateral invasive adenocarcinoma of the breast on histologic examination.
    • Patient must have undergone axillary staging (sentinel node biopsy and/or axillary node dissection).
    • The following staging criteria must be met postoperatively according to AJCC 8th edition criteria:
    • By pathologic evaluation, primary tumor must be pT1 (less than or equal to 2 cm).
    • By pathologic evaluation, ipsilateral nodes must be pN0. (Patients with pathologic staging of pN0(i+) or pN0(mol+) are NOT eligible.)

    • Oncotype DX Recurrence Score of less than or equal to 18 on diagnostic core biopsy or resected specimen.

      ** For patients with a T1a tumor (less than or equal to 0.5 cm in size) or patients at Canadian provinces or approved international sites where Oncotype DX Recurrence Score testing would not be covered, who do not already have an Oncotype DX Recurrence Score at pre-entry/Step 1, a specimen (unstained blocks or slides) must be sent to the Genomic Health centralized laboratory. Tumor size sample must be greater than or equal to 0.2 cm for analysis.

      *** The Oncotype RS can be run on the biopsy core or surgical specimen. The patient cannot have initiated endocrine therapy prior to tissue collection.

    • An Oncotype RS is required for eligibility, however, for a patient whose tumor has already had a MammaPrint test completed as part of usual care when being considered for enrollment and is in the binary "Low" category will meet this eligibility criteria and an Oncotype RS does not need to be performed.
    • The tumor must have been determined to be ER and/or PgR positive assessed by current ASCO/CAP Guideline Recommendations for hormone receptor testing. Patients with greater than or equal to 1% ER or PgR staining by IHC are considered positive.
    • The tumor must have been determined to be HER2-negative by current ASCO/CAP guidelines.
    • Patients may be premenopausal or postmenopausal at the time of pre-entry/Step 1. For study purposes, postmenopausal is defined as:
    • Age 56 or older with no spontaneous menses for at least 12 months prior to pre-entry/Step 1; or a documented hysterectomy; or
    • Age 55 or younger with no spontaneous menses for at least 12 months prior to pre-entry/Step 1 (e.g., spontaneous or secondary to hysterectomy) and with a documented estradiol level in the postmenopausal range according to local institutional/laboratory standard; or Documented bilateral oophorectomy.
    • The interval between the last surgery for breast cancer (including re-excision of margins) and pre-entry/Step 1 must be no more than 70 days.
    • The patient must have recovered from surgery with the incision completely healed and no signs of infection.
    • Bilateral mammogram or MRI within 6 months prior to pre-entry/Step 1. HIV-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial. Patients must be intending to take endocrine therapy for a minimum 5 years duration (tamoxifen or aromatase inhibitor). The specific regimen of endocrine therapy is at the treating physician's discretion.

Exclusion Criteria:

  • • Definitive clinical or radiologic evidence of metastatic disease.

    • pT1 mi and pT2 - pT4 tumors including inflammatory breast cancer.
    • Pathologic staging of pN0(i+) or pN0(mol+), pN1, pN2, or pN3 disease.
    • Patient had a mastectomy.
    • Palpable or radiographically suspicious ipsilateral or contralateral axillary, supraclavicular, infraclavicular, or internal mammary nodes, unless there is histologic confirmation that these nodes are negative for tumor.
    • Suspicious microcalcifications, densities, or palpable abnormalities (in the ipsilateral or contralateral breast) unless biopsied and found to be benign.
    • Non-epithelial breast malignancies such as sarcoma or lymphoma.
    • Proven multicentric carcinoma (invasive cancer or DCIS) in more than one quadrant or separated by 4 or more centimeters. (Patients with multifocal carcinoma are eligible.)
    • Paget's disease of the nipple.
    • Any history, not including the index cancer, of ipsilateral invasive breast cancer or ipsilateral DCIS treated or not treated. (Patients with synchronous or previous ipsilateral LCIS are eligible.)
    • Synchronous or previous contralateral invasive breast cancer or DCIS. (Patients with synchronous and/or previous contralateral LCIS are eligible.)
    • Surgical margins that cannot be microscopically assessed or are positive at pathologic evaluation. (If surgical margins are rendered free of disease by re- excision, the patient is eligible.)
    • Treatment plan that includes regional nodal irradiation.
    • Any treatment with radiation therapy, chemotherapy, or biotherapy, administered for the currently diagnosed breast cancer prior to pre-entry/Step 1.
    • History of non-breast malignancies (except for in situ cancers treated only by local excision and basal cell and squamous cell carcinomas of the skin) within 5 years prior to pre-entry/Step 1.

    • Current therapy with any endocrine therapy such as raloxifene (Evista®), tamoxifen, or other selective estrogen receptor modulators (SERMs), either for osteoporosis or breast cancer prevention.

      ** Patients are eligible for BR007 if they receive a short course of preoperative endocrine therapy of less than 6 weeks duration (prior to randomization/Step 2) for this diagnosis after the core biopsy (and can continue postoperatively if:

    • the Oncotype DX Recurrence Score is assessed on the biopsy core and is less than or equal to 18, AND

    • the patient had not initiated endocrine therapy prior to core biopsy tissue collection.

      *** This does not apply to adjuvant endocrine therapy recommended for this diagnosis which may start any time after surgery including prior to registration (Pre-entry/Step 1).

    • Patients intending to continue on oral, transdermal, or subdermal estrogen replacement (including all estrogen only and estrogen-progesterone formulas) are not eligible. Patients that discontinue oral, transdermal, or subdermal estrogen replacement prior to registration are eligible.
    • Prior breast or thoracic RT for any condition.
    • Active collagen vascular disease, specifically dermatomyositis with a CPK level above normal or with an active skin rash, systemic lupus erythematosis, or scleroderma.
    • Pregnancy or lactation at the time of pre-entry/Step 1 or intention to become pregnant during treatment. (Note: Pregnancy testing according to institutional standards for women of childbearing potential must be performed within 2 weeks prior to pre-entry/Step 1.)
    • Any other disease, metabolic dysfunction, physical examination finding, or clinical laboratory finding giving reasonable suspicion of a disease or condition that contraindicates the use of study therapy or that may affect the interpretation of the results or render the patient at high risk from treatment complications.
    • Psychiatric or addictive disorders or other conditions that, in the opinion of the investigator, would preclude the patient from meeting the study requirements or interfere with interpretation of study results.
    • Use of any investigational product within 30 days prior to pre-entry/Step 1.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Arm 1: Breast Radiation Therapy + Endocrine Therapy
Radiation therapy to the breast and hormonal drug for at least 5 years. Tamoxifen 20 mg daily Anastrozole 1 mg daily Letrozole 2.5 mg daily Exemestane 25 mg daily
Other: Radiation and Endocrine Therapy (Tamoxifen, Anastrozol, Letrozole, Exemestane)

Post lumpectomy radiation therapy will be external beam radiation to either the whole breast + boost, partial breast irradiation, or Accelerated Partial Breast Irradiation that must begin within 12 weeks of the last breast cancer surgery(including re-excision of margins).

Endocrine therapy for a minimum of 5 years. The specific regimen of endocrine therapy is at the treating physician's discretion. The dose and schedule of the drug(s) used for endocrine therapy should be consistent with the instructions in the drug package insert(s). Endocrine therapy may be initiated before, during, or after completion of radiation therapy at the discretion of the investigator.
Active Comparator: Arm 2: No Breast Radiation Therapy + Endocrine Therapy
No radiation therapy, only hormonal drug for at least 5 years. Tamoxifen 20 mg daily Anastrozole 1 mg daily Letrozole 2.5 mg daily Exemestane 25 mg daily
Drug: Endocrine Therapy (Tamoxifen, Anastrozol, Letrozole, Exemestane)
Endocrine therapy for a minimum of 5 years. The specific regimen of endocrine therapy is at the treating physician's discretion. The dose and schedule of the drug(s) used for endocrine therapy should be consistent with the instructions in the drug package insert(s).

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Time to invasive or noninvasive IBTR.
Time Frame: 5 years
Time from randomization to any invasive or noninvasive IBTR or last follow-up (expressed as % IBTR-free)
5 years

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Percent of women with an intact index breast at report of the primary endpoint inclusive of salvage second breast conservation procedures.
Time Frame: Through study completion, an average of 15 years.
Time from randomization to any breast procedure after the initial surgery or last follow-up (expressed as % with intact index breast)
Through study completion, an average of 15 years.
Time from randomization to the first occurrence of invasive ipsilateral breast tumor recurrence.
Time Frame: 5 years
Time from randomization to any invasive IBTR or last follow-up (expressed as percentage of invasive IBTR-free
5 years
Time from randomization to diagnosis of a local, regional or distant recurrence as a first cancer event.
Time Frame: 5 years
Time from randomization to any breast cancer recurrence at a local, regional or distant site or last follow-up (expressed as percentage of recurrence-free)
5 years
Time from randomization to the first distant cancer event (either a recurrence or a secondary primary cancer).
Time Frame: 5 years
Time from randomization to any cancer occurring at a distant site or last follow-up (expressed as percentage of distant disease-free)
5 years
Time from randomization to any death.
Time Frame: 5 years
Time from randomization to any death or last follow-up (expressed as percent surviving)
5 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

NRG Oncology

Collaborators

National Cancer Institute (NCI)

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 23, 2021

Primary Completion (Estimated)

April 8, 2031

Study Completion (Estimated)

July 1, 2041

Study Registration Dates

First Submitted

April 16, 2021

First Submitted That Met QC Criteria

April 20, 2021

First Posted (Actual)

April 21, 2021

Study Record Updates

Last Update Posted (Actual)

April 23, 2026

Last Update Submitted That Met QC Criteria

April 22, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • NRG-BR007
  • 5U10CA180868-07 (U.S. NIH Grant/Contract)
  • NCI-2021-00222 (Registry Identifier: CTRP)

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Stage I Breast Cancer

Clinical Trials on Radiation and Endocrine Therapy (Tamoxifen, Anastrozol, Letrozole, Exemestane)

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uganda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe