Stroke Thrombectomy and Aneurysm Registry (STAR)

December 18, 2025 updated by: Alejandro Spiotta, Medical University of South Carolina
This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood vessels, abnormal formation of blood vessels, tearing of vein, and bleeding in the brain. This information is used to help predict outcomes that undergo an operation for treatment of the above-listed brain injuries. Additionally, the information is used to compare techniques and devices' effects on technical and clinical outcomes.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

40000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

  • Name: Alejandro M Spiotta, MD
  • Phone Number: 843-792-9226
  • Email: spiotta@musc.edu

Study Contact Backup

  • Name: Meredith Robinson, MS
  • Phone Number: 843-792-3164
  • Email: robme@musc.edu

Study Locations

  • Canada
      • Saskatoon, Canada
        • Recruiting
        • University of Saskatchewan
        • Contact:
        • Principal Investigator:
          • Uzair Ahmed, MD
  • Germany
  • Japan
      • Hyōgo, Japan
  • Portugal
      • Lisbon, Portugal
        • Recruiting
        • Centro Hospitalar Universitário de Lisboa Central
        • Principal Investigator:
          • Isabel Fragata, MD,PHD
        • Contact:
          • Isabel Fragata, MD,PHD
  • South Korea
      • Gwangju, South Korea
  • Spain
      • Madrid, Spain
        • Recruiting
        • Hospital Universitario La Paz
        • Contact:
          • Pedro Navia, MD, PhD
        • Principal Investigator:
          • Pedro Navia, MD, PhD
  • Switzerland
      • Basel, Switzerland
        • Recruiting
        • Universitätsspital Basel
        • Contact:
        • Principal Investigator:
          • Marios-Nikos Psychogios, MD
  • United States
    • Alabama
      • Birmingham, Alabama, United States, 35233
        • Recruiting
        • University of Alabama at Birmingham
        • Principal Investigator:
          • Elizabeth Liptrap, MD
        • Contact:
    • California
      • Loma Linda, California, United States, 92350
        • Recruiting
        • Loma Linda University
        • Contact:
        • Principal Investigator:
          • Justin Dye, MD
      • Santa Barbara, California, United States, 93105
        • Recruiting
        • Cottage Health Research Institute
        • Contact:
        • Principal Investigator:
          • Brian Walcott, MD
    • Connecticut
      • Danbury, Connecticut, United States, 06810
      • New Haven, Connecticut, United States, 06520
        • Recruiting
        • Yale University
        • Principal Investigator:
          • Charles Matouk, MD
        • Contact:
    • Florida
      • Gainesville, Florida, United States, 32611
        • Recruiting
        • University of Florida
        • Contact:
        • Sub-Investigator:
          • Brian Hoh, MD
        • Principal Investigator:
          • Nohra Chalouhi, MD
        • Contact:
      • Jacksonville, Florida, United States, 32224
        • Recruiting
        • Mayo Clinic in Florida
        • Contact:
        • Principal Investigator:
          • Christopher Fox, MD
      • Miami, Florida, United States, 33136
        • Recruiting
        • University of Miami Health System
        • Contact:
        • Contact:
        • Principal Investigator:
          • Robert Starke, MD, MSC
        • Sub-Investigator:
          • Dileep Yavagal, MD
        • Sub-Investigator:
          • Eric Peterson, MD
      • Tampa, Florida, United States, 33620
        • Recruiting
        • University of South Florida
        • Contact:
          • Maxim Mokin, MD, PhD
        • Principal Investigator:
          • Maxim Mokin, MD, PhD
        • Sub-Investigator:
          • Waldo Guerrero, MD
        • Sub-Investigator:
          • Konrad Bach
    • Georgia
      • Atlanta, Georgia, United States, 30322
      • Atlanta, Georgia, United States, 30318
        • Recruiting
        • Piedmont Healthcare
        • Contact:
        • Principal Investigator:
          • Michael Stiefel, MD
    • Hawaii
      • Honolulu, Hawaii, United States, 96813
        • Recruiting
        • The Queens Health Center
        • Contact:
        • Principal Investigator:
          • Sam Tsappidi, MD
    • Illinois
      • Chicago, Illinois, United States, 60637
      • Chicago, Illinois, United States, 60612
        • Recruiting
        • Rush University
        • Contact:
        • Principal Investigator:
          • Richard Crowley, MD
        • Sub-Investigator:
          • Michael Chen, MD
        • Contact:
      • Chicago, Illinois, United States, 60637
        • Recruiting
        • University of Illinois
        • Principal Investigator:
          • Ali Alaraj, MD
        • Contact:
      • Evanston, Illinois, United States, 60201
        • Recruiting
        • Endeavor Health
        • Principal Investigator:
          • Shakeel Chowdhry, MD
        • Contact:
    • Indiana
      • Indianapolis, Indiana, United States, 46202
        • Recruiting
        • Indiana University
        • Principal Investigator:
          • Kaustubh Limaye, MD
        • Contact:
          • Kaustubh Limaye, MD
          • Phone Number: 317-948-5450
          • Email: klimaye@iu.edu
    • Iowa
      • Iowa City, Iowa, United States, 52242
        • Recruiting
        • University of Iowa
        • Contact:
        • Contact:
        • Sub-Investigator:
          • Edgar Samaniego, MD
        • Principal Investigator:
          • Amir Shaban, MD
    • Kansas
      • Kansas City, Kansas, United States, 66103
        • Recruiting
        • University of Kansas Medical Center
        • Contact:
        • Principal Investigator:
          • Jeremy Peterson, MD
    • Kentucky
      • Louisville, Kentucky, United States, 40292
    • Louisiana
      • New Orleans, Louisiana, United States, 70112
        • Recruiting
        • Tulane University
        • Contact:
        • Principal Investigator:
          • Kendrick Johnson, MD
      • Shreveport, Louisiana, United States, 71103
        • Recruiting
        • Louisiana State University Health Shreveport
        • Contact:
        • Principal Investigator:
          • Hugo Cuellar, MD, PhD
    • Massachusetts
      • Boston, Massachusetts, United States, 02215
        • Recruiting
        • Beth Israel Deaconess Medical Center
        • Contact:
        • Contact:
        • Principal Investigator:
          • Christopher Ogilvy, MD
        • Sub-Investigator:
          • Ajith Thomas, MD
        • Sub-Investigator:
          • Justin Moore, MD
    • Michigan
      • Ann Arbor, Michigan, United States, 48109
        • Recruiting
        • University of Michigan
        • Contact:
        • Principal Investigator:
          • Aditya Pandey, MD
      • Wyoming, Michigan, United States, 49519
        • Recruiting
        • University of Michigan Health-West
        • Contact:
        • Principal Investigator:
          • Fazeel Siddiqui, MD, FAHA
    • Minnesota
      • Rochester, Minnesota, United States, 55905
        • Recruiting
        • Mayo Clinic
        • Contact:
        • Principal Investigator:
          • Waleed Brinjikji, MD
    • Missouri
      • St Louis, Missouri, United States, 63110
        • Recruiting
        • Washington University in St. Louis
        • Contact:
        • Contact:
        • Principal Investigator:
          • Joshua Osbun, MD
    • New Hampshire
      • Portsmouth, New Hampshire, United States, 03801
    • New Jersey
      • New Brunswick, New Jersey, United States, 08901
        • Recruiting
        • Rutgers University
        • Principal Investigator:
          • Gaurav Gupta, MD
        • Contact:
          • Gaurav Gupta, MD
      • Pennington, New Jersey, United States, 08534
        • Recruiting
        • Global Neurosciences Institute
        • Contact:
        • Principal Investigator:
          • Mandy Binning, MD
    • New York
      • Albany, New York, United States, 12208
        • Recruiting
        • Albany Medical Center
        • Principal Investigator:
          • Alexandra Paul, MD
        • Contact:
      • Great Neck, New York, United States, 11021
        • Recruiting
        • The Feinstein Institutes for Medical Research
        • Principal Investigator:
          • Timothy White, MD
        • Contact:
      • Stony Brook, New York, United States, 11794
      • The Bronx, New York, United States, 10467
        • Recruiting
        • Montefiore Medical Center
        • Principal Investigator:
          • David Altschul, MD
        • Contact:
    • North Carolina
      • Raleigh, North Carolina, United States, 27607
        • Recruiting
        • University of North Carolina
        • Principal Investigator:
          • Omar Kass-hout, MD
        • Contact:
          • Omar Kass-hout, MD
      • Winston-Salem, North Carolina, United States, 27157
        • Recruiting
        • Wake Forest Baptist Health
        • Contact:
        • Contact:
        • Sub-Investigator:
          • Kyle Fargen, MD
        • Sub-Investigator:
          • Patrick Brown, MD
        • Principal Investigator:
          • Stacey Wolfe, MD
    • Ohio
      • Toledo, Ohio, United States, 43608
        • Recruiting
        • Mercy Health
        • Principal Investigator:
          • Osama Zaidat, MD
        • Contact:
          • Osama Zaidat, MD
    • Oklahoma
      • Oklahoma City, Oklahoma, United States, 73019
        • Recruiting
        • University of Oklahoma
        • Principal Investigator:
          • Andrew Bauer, MD
        • Contact:
    • Pennsylvania
      • Philadelphia, Pennsylvania, United States, 19107
        • Recruiting
        • Thomas Jefferson University
        • Contact:
        • Contact:
        • Sub-Investigator:
          • Stavropoula Tjoumakaris, MD
        • Sub-Investigator:
          • M. Reid Gooch, MD
        • Sub-Investigator:
          • Nabeel Herial, MD
        • Principal Investigator:
          • Pascal Jabbour, MD
      • Pittsburgh, Pennsylvania, United States, 15212
        • Recruiting
        • Alleghany Hospital
        • Contact:
        • Principal Investigator:
          • Russell Cerejo, MD
      • Wilkes-Barre, Pennsylvania, United States, 18702
        • Recruiting
        • Geisinger Medical Group
        • Principal Investigator:
          • Clemens Schirmer, MD, PhD
        • Contact:
      • York, Pennsylvania, United States, 17403
        • Recruiting
        • Wellspan York Hospital
        • Contact:
          • Michael Casey, DO
        • Principal Investigator:
          • Michael Casey, DO
    • South Carolina
      • Charleston, South Carolina, United States, 29425
        • Recruiting
        • Medical University of South Carolina
        • Contact:
        • Contact:
          • Meredith M Robinson, MS
          • Phone Number: 843-792-3164
          • Email: robme@musc.edu
    • Tennessee
      • Memphis, Tennessee, United States, 38163
        • Recruiting
        • University of Tennessee Health Science Center
        • Contact:
        • Sub-Investigator:
          • Nitin Goyal, MD
        • Sub-Investigator:
          • Daniel Hoit, MD
        • Sub-Investigator:
          • Violiza Inoia-Acosta, MD
        • Principal Investigator:
          • Adam Arthur, MD
        • Contact:
    • Texas
      • Galveston, Texas, United States, 77555
        • Recruiting
        • The University of Texas Medical Branch at Galveston
        • Contact:
        • Principal Investigator:
          • Peter Kan, MD
      • Harlingen, Texas, United States, 78550
        • Recruiting
        • Valley Baptist Medical Center
        • Principal Investigator:
          • Ameer Hassan, DO
        • Contact:
      • Houston, Texas, United States, 77030
        • Recruiting
        • Baylor College of Medicine
        • Contact:
        • Contact:
        • Principal Investigator:
          • Omar Tanweer, MD
      • Kingwood, Texas, United States, 77339
        • Recruiting
        • HCA Houston Healthcare Kingwood
        • Contact:
          • Mohamad Ezzeldin, MD
        • Principal Investigator:
          • Mohamad Ezzeldin, MD
      • Plano, Texas, United States, 75075
        • Recruiting
        • Texas Stroke Institute
        • Principal Investigator:
          • Albert Yoo, MD
        • Contact:
          • Albert Yoo, MD
      • San Antonio, Texas, United States, 78229
        • Recruiting
        • University of Texas Health Science Center at San Antonio
        • Principal Investigator:
          • Justin Mascitelli, MD
        • Contact:
    • Utah
      • Salt Lake City, Utah, United States, 84112
        • Recruiting
        • University of Utah
        • Contact:
        • Principal Investigator:
          • Ramesh Grandhi, MD, MS
    • Virginia
      • Charlottesville, Virginia, United States, 22904
        • Recruiting
        • University of Virginia
        • Contact:
        • Contact:
        • Principal Investigator:
          • Ryan Kellogg, MD
    • Washington
      • Seattle, Washington, United States, 98195
        • Recruiting
        • University of Washington
        • Contact:
        • Contact:
        • Sub-Investigator:
          • Louis Kim, MD
        • Principal Investigator:
          • Michael Levitt, MD
    • West Virginia
      • Morgantown, West Virginia, United States, 26506
  • Uruguay
      • Montevideo, Uruguay

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

1 year to 120 years (Child, Adult, Older Adult)

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Any patients between 1 and 120 years of age, undergoing surgical intervention for central nervous system vascular lesions.

Description

Inclusion Criteria:

  • Undergoing surgical intervention for central nervous system vascular lesion
  • Between 1 and 120 years of age

Exclusion Criteria:

  • No exclusion criteria

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Stroke
Procedure: Stroke/Thrombectomy/Aneurysm-specific surgical procedures
Participants are retrospectively and/or prospectively entered into registry based on disease indication and respective surgical procedure.
Thrombectomy
Procedure: Stroke/Thrombectomy/Aneurysm-specific surgical procedures
Participants are retrospectively and/or prospectively entered into registry based on disease indication and respective surgical procedure.
Aneurysm
Procedure: Stroke/Thrombectomy/Aneurysm-specific surgical procedures
Participants are retrospectively and/or prospectively entered into registry based on disease indication and respective surgical procedure.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Post-procedure hemorrhage rate changes
Time Frame: 90 days
Researchers examine changes in hemorrhage rates in post-stroke patients
90 days
Occlusion rates
Time Frame: 90 days
Measure of how thrombectomy procedure success in relation to reduced occlusion
90 days
Complication rates
Time Frame: 90 days
Measure of post-procedure complication rates in stroke/aneurysm patients
90 days
Retreatment rates
Time Frame: 90 days
Measure of patient retreatment post-procedure
90 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Medical University of South Carolina

Investigators

  • Study Director: Meredith Robinson, MS, Medical University of South Carolina

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 17, 2019

Primary Completion (Estimated)

January 1, 2055

Study Completion (Estimated)

January 1, 2055

Study Registration Dates

First Submitted

August 3, 2021

First Submitted That Met QC Criteria

August 3, 2021

First Posted (Actual)

August 6, 2021

Study Record Updates

Last Update Posted (Actual)

December 24, 2025

Last Update Submitted That Met QC Criteria

December 18, 2025

Last Verified

December 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Pro00090704

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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