the Effects of Air Pollution on Respiratory Diseases in Children

July 29, 2022 updated by: Baoping XU, Beijing Children's Hospital

A Multicenter Observational Study of the Effects of Air Pollution on Respiratory Diseases in Children

The investigators expect to reveal the association between air pollution and childhood respiratory diseases through a multi-center observational study, and summarize the relationship between air pollution and childhood respiratory diseases.

Study Overview

Status

Recruiting

Conditions

Detailed Description

The investigators will collect the data of outpatient and emergency children in Beijing Children's hospital and other participating hospitals due to respiratory diseases from 2010 to 2021, , collect clinical data and basic information, obtain air pollution data and meteorological monitoring data and perform data processing and statistical analysis,，then analyzes the impact of air pollution on children's respiratory diseases.

Study Type

Observational

Enrollment (Anticipated)

2000000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Beijing
      • Beijing, Beijing, China, 100045
        • Recruiting
        • Baoping Xu

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

3 years to 14 years (Child, Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

All children aged between 0-18 years who visited Beijing Children's hospital or other hospitals participating in the project due to respiratory diseases from 2010 to 2021.

Description

Inclusion Criteria:

  • All children participating in this clinical study must meet all of the following criteria:

    1. Age: 0-18 years old, male and female
    2. Consultation for respiratory diseases
    3. Visit time is between 2010-2021
    4. Provide complete personally identifiable information and medical information

Exclusion Criteria:

  • All children with any of the following conditions must be excluded from this study:

    1. children who visit hospital don't for respiratory diseases
    2. children participating in this clinical study don't provide complete personally identifiable information and medical information
    3. Visit time is not between 2010-2021.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Only
  • Time Perspectives: Retrospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Major air pollutant concentrations
Time Frame: 12 years
The air pollutant data comes from the daily air quality data published by the National Environmental Monitoring Center. Calculate the arithmetic average of the daily average concentrations of air pollutants (PM10, PM2.5, SO, NO, CO, etc.) Converted from air pollution index (API).
12 years

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Number of daily visits for respiratory diseases in outpatient and emergency departments
Time Frame: 12 years
The number of daily outpatient visits for respiratory diseases( rhinitis, allergic rhinitis, upper respiratory tract infection, bronchitis and bronchiolitis, bronchiolitis obliterans, pneumonia, asthma , allergic cough, chronic cough, upper airway cough syndrome,etc.) in each hospital participating in this study during the study period.
12 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Beijing Children's Hospital

Collaborators

The First Affiliated Hospital of Anhui Medical University
The First Affiliated Hospital of Guangzhou Medical University
China-Japan Friendship Hospital
First Affiliated Hospital of Xinjiang Medical University
Kunming Children's Hospital
Guangzhou Women and Children's Medical Center
Jiangxi Province Children's Hospital
Shenzhen Children's Hospital
The First Affiliated Hospital of Xiamen University
Xian Children's Hospital
Shanxi Provincial Maternity and Children's Hospital
Wuhan Children's Hospital
Tianjin Children's Hospital
Capital Institute of Pediatrics, China
Xianyang Children's Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 15, 2022

Primary Completion (Anticipated)

December 31, 2022

Study Completion (Anticipated)

December 31, 2022

Study Registration Dates

First Submitted

January 14, 2022

First Submitted That Met QC Criteria

July 29, 2022

First Posted (Actual)

August 2, 2022

Study Record Updates

Last Update Posted (Actual)

August 2, 2022

Last Update Submitted That Met QC Criteria

July 29, 2022

Last Verified

July 1, 2022

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • BCH Lung 016

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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