A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation (HERMES)
March 31, 2024 updated by: Novo Nordisk A/S
HERMES: Effects of Ziltivekimab Versus Placebo on Morbidity and Mortality in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Systemic Inflammation
This study will be done to see if ziltivekimab can be used to treat people living with heart failure and inflammation.
Participants will either get ziltivekimab or placebo.
Participants will get study medicine for once-monthly injections either in a pre-filled syringe to inject the study medicine into a skinfold or a pen-injector to inject the study medicine into flat skin.
The study is expected to last for up to 4 years.
Participants will have up to 20 clinic visits.
Participants will have to use a study app on their phone to record and share information about all their injections of study medicine and to fill in questionnaires.
Study Overview
Status
Recruiting
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Estimated)
5600
Phase
- Phase 3
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Novo Nordisk
- Phone Number: (+1) 866-867-7178
- Email: clinicaltrials@novonordisk.com
Study Locations
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-
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Buenos Aires, Argentina, B1704ETD
- Recruiting
- DIM Clínica Privada
-
Buenos Aires, Argentina, C1181ACH
- Not yet recruiting
- Hospital Italiano
-
Caba, Argentina, C1093AAS
- Recruiting
- Fundacion Favaloro
-
Caba, Argentina, C1093AAS
- Not yet recruiting
- Fundacion Favaloro
-
Caba, Argentina, C1440CFD
- Recruiting
- CEMEDIC
-
Corrientes, Argentina, W3400AMZ
- Recruiting
- Instituto de Cardiologia de Corrientes
-
Mar del Plata, Argentina, B7600FZN
- Recruiting
- Instituto de Investigaciones Clinicas
-
Mar del Plata, Argentina, B7600GNY
- Recruiting
- Centro de Investigaciones Médicas Clínica de Fracturas y Or
-
San Nicolás, Argentina, B2900
- Recruiting
- Instituto de Investigaciones Clinicas San Nicolás
-
Santa Fe, Argentina, 3000
- Recruiting
- Centro de Investigaciones Clinicas del Litoral
-
-
Buenos Aires
-
Caba, Buenos Aires, Argentina, C1128 AAF
- Recruiting
- Mautalen Salud e investigación
-
Mar del Plata, Buenos Aires, Argentina, B7600GNY
- Recruiting
- Centro de Investigaciones Médicas Clínica de Fracturas y Or
-
-
Santa Fe
-
Granadero Baigorria, Santa Fe, Argentina, 2152
- Recruiting
- Centro de Investigaciones Clinica Baigorria
-
-
-
-
Australian Capital Territory
-
Garran, Australian Capital Territory, Australia, 2605
- Recruiting
- The Canberra Hospital_Garran
-
-
New South Wales
-
Concord, New South Wales, Australia, 2139
- Recruiting
- Concord Repatriation General Hospital - Cardiology
-
Gosford, New South Wales, Australia, 2250
- Recruiting
- Gosford Hospital
-
-
Queensland
-
Brisbane, Queensland, Australia, 4029
- Not yet recruiting
- Royal Brisbane and Women's Hospital
-
-
South Australia
-
Adelaide, South Australia, Australia, 5000
- Recruiting
- Nightingale Research
-
Adelaide, South Australia, Australia, 5000
- Recruiting
- Royal Adelaide Hospital Cardiovascular Clinical Trials
-
Bedford Park, South Australia, Australia, 5042
- Recruiting
- Flinders Medical Centre
-
-
Tasmania
-
Hobart, Tasmania, Australia, 7000
- Recruiting
- Royal Hobart Hospital
-
-
Victoria
-
Frankston, Victoria, Australia, 3199
- Recruiting
- Frankston Hospital
-
Geelong, Victoria, Australia, 3220
- Recruiting
- Barwon Health (The Geelong Hospital)
-
-
-
-
-
Braunau, Austria, A 5280
- Not yet recruiting
- Krankenhaus St. Josef Braunau
-
Braunau, Austria, A 5280
- Recruiting
- Krankenhaus St. Josef Braunau
-
Graz, Austria, A 8036
- Recruiting
- Medizinische Universität Graz
-
Saint Stefan, Austria, 8511
- Recruiting
- Fließer-Görzer [Ordination]
-
Saint Stefan, Austria, 8511
- Not yet recruiting
- Fließer-Görzer [Ordination]
-
Salzburg, Austria, 5020
- Not yet recruiting
- Uniklinikum Salzburg Kardiologie
-
Vienna, Austria, 1090
- Not yet recruiting
- Medizinische Universität Wien
-
Vienna, Austria, 1090
- Withdrawn
- Medizinische Universität Wien
-
Vienna, Austria, 1160
- Withdrawn
- Klinik Ottakring
-
Wien, Austria, 1100
- Not yet recruiting
- Klinik Favoriten
-
Wien, Austria, A 1190
- Not yet recruiting
- Imed 19- privat
-
Wien, Austria, A 1190
- Recruiting
- Imed 19- privat
-
-
-
-
-
Aalst, Belgium, 9300
- Recruiting
- OLV Ziekenhuis Aalst-Asse-Ninove
-
Brussel, Belgium, 1090
- Recruiting
- UZ Brussel
-
Edegem, Belgium, 2650
- Recruiting
- UZA - UZ Antwerpen - Cardiology Department
-
Genk, Belgium, 3600
- Recruiting
- Ziekenhuis Oost-Limburg AV - Cardiology
-
Kortrijk, Belgium, 8500
- Recruiting
- AZ Groeninge - Kortrijk - Cardiology
-
Liège, Belgium, 4000
- Recruiting
- CHR de la Citadelle
-
-
-
-
-
Banja Luka, Bosnia and Herzegovina, 78000
- Recruiting
- University Clinical Centre of the Republic Srpska
-
Sarajevo, Bosnia and Herzegovina, 71000
- Recruiting
- Dr. Abdulah Nakas General Hospital
-
Sarajevo, Bosnia and Herzegovina, 71000
- Recruiting
- University Clinical Centre Sarajevo
-
-
-
-
-
Aracaju, Brazil, 49055-530
- Recruiting
- jmf Clinica do Coracao ltda
-
Belo Horizonte/MG, Brazil, 30220-140
- Recruiting
- Nucleo de Pesquisa Clinica do Hospital Vera Cruz
-
Goiânia/GO, Brazil, 74605-020
- Recruiting
- Hospital de Clínicas da Universidade Federal de Goiânia
-
Marília/SP, Brazil, 17515-000
- Recruiting
- ICM - Instituto do Coração de Marília
-
Porto Alegre/RS, Brazil, 90840-440
- Recruiting
- Hospital Mãe de Deus - Porto Alegre
-
Recife/PE, Brazil, 56517-630
- Withdrawn
- Procape
-
Ribeirão Preto/SP, Brazil, 14051-140
- Withdrawn
- Hospital das Clínicas de Ribeirão Preto
-
Rio de Janeiro, Brazil, 22281-100
- Withdrawn
- Instituto D'Or de Pesquisa e Ensino
-
São Paulo/SP, Brazil, 04026-090
- Not yet recruiting
- Universidade Federal de São Paulo - UNIFESP
-
-
Espirito Santo
-
Vitória, Espirito Santo, Brazil, 29055-450
- Withdrawn
- Centro de Diag. e Pesquisa da Osteoporose do Espírito Santo
-
-
Minas Gerais
-
Belo Horizonte, Minas Gerais, Brazil, 30150-320
- Recruiting
- CCIH-Consultoria em Controle de Infecção Hospitalar Ltda
-
-
RJ
-
Rio de Janeiro, RJ, Brazil, 22061-080
- Recruiting
- Hospital São Lucas Copacabana
-
-
Rio Grande Do Sul
-
Porto Alegre, Rio Grande Do Sul, Brazil, 90035-003
- Recruiting
- Hospital de Clinicas de Porto Alegre
-
-
Sao Paulo
-
Campinas, Sao Paulo, Brazil, 13060-080
- Recruiting
- Instituto de Pesquisa Clínica de Campinas
-
Campinas, Sao Paulo, Brazil, 13092-133
- Recruiting
- Loema Med e Bem Estar Centro Especializado em Cardiologia
-
Campinas, Sao Paulo, Brazil, 13060-803
- Recruiting
- PUCCAMP - Hospital e Maternidade Celso Pierro
-
São José do Rio Preto, Sao Paulo, Brazil, 15090-000
- Recruiting
- CIP Centro Integrado de Pesquisas do Hospital de Base
-
-
São Paulo
-
Cidade Nova Votuporanga, São Paulo, Brazil, 15501-405
- Recruiting
- Integral Pesquisa e Ensino
-
-
-
-
-
Burgas, Bulgaria, 8000
- Recruiting
- MHAT Hearth and brain EAD
-
Kozloduy, Bulgaria, 3320
- Recruiting
- Medical centre "Zdrave 1" OOD
-
Lom, Bulgaria, 3600
- Recruiting
- Diagnostic Consulting Center 1- Lom EOOD
-
Panagyurishte, Bulgaria, 4500
- Recruiting
- "MHAT - UniHospital" OOD
-
Pleven, Bulgaria, 5800
- Recruiting
- "Medical center Medconsult Pleven" OOD
-
Pleven, Bulgaria, 5800
- Recruiting
- UMHAT Heart and Brain
-
Plovdiv, Bulgaria, 4002
- Recruiting
- "UMHAT "Sveti Georgi" EAD
-
Sandanski, Bulgaria, 2800
- Recruiting
- Medical centre Health Care OOD
-
Sevlievo, Bulgaria, 5400
- Recruiting
- 'Medical Center Hipokrena' EOOD
-
Sofia, Bulgaria, 1233
- Recruiting
- MHAT "Knyaginya Klementina" -Sofia EAD
-
Sofia, Bulgaria, 1202
- Recruiting
- Diagnostic Consulting Center Ascendent
-
Sofia, Bulgaria, 1431
- Recruiting
- "Diagnostic - Consulting Center Aleksandrovska" EOOD
-
Sofia, Bulgaria, 1233
- Recruiting
- National Multiprofile Transport Hospital "Tsar Boris III"
-
Sofia, Bulgaria, 1527
- Recruiting
- Medico-dental center ISUL - Tsaritsa Yoanna EOOD
-
Stara Zagora, Bulgaria, 6000
- Recruiting
- "Medical center Zara-Med" EOOD
-
Veliko Tarnovo, Bulgaria, 5000
- Recruiting
- MDHAT "Dr. Stephen Cherkezov" AD
-
-
-
-
Alberta
-
Calgary, Alberta, Canada, T2N 4Z6
- Recruiting
- University of Calgary_Calgary
-
Edmonton, Alberta, Canada, T5A 4L8
- Recruiting
- Alta Clinical Research
-
-
British Columbia
-
New Westminster, British Columbia, Canada, V3L 3W4
- Recruiting
- Royal Columbian Hospital
-
North Vancouver, British Columbia, Canada, V7M 2H4
- Recruiting
- North Shore Heart Centre
-
North Vancouver, British Columbia, Canada, V7M 2H4
- Not yet recruiting
- North Shore Heart Centre
-
Surrey, British Columbia, Canada, V3V 0C6
- Recruiting
- SMH Cardiology Clinical Trials Inc.
-
Vancouver, British Columbia, Canada, V5Z 1M9
- Recruiting
- Ctr for Cardiovascular Innovation
-
Vancouver, British Columbia, Canada, V6Z1Y6
- Not yet recruiting
- St Pauls Hospital
-
Victoria, British Columbia, Canada, V8R 1B2
- Recruiting
- Victoria Heart Institute Foundation
-
-
Manitoba
-
Winnipeg, Manitoba, Canada, R2H 2HA6
- Recruiting
- St. Boniface Hospital
-
-
New Brunswick
-
Moncton, New Brunswick, Canada, E1G 1A7
- Recruiting
- G.A. Research Associates Ltd.
-
-
Nova Scotia
-
Halifax, Nova Scotia, Canada, B3H 3A7
- Recruiting
- Nova Scotia Health
-
-
Ontario
-
Cambridge, Ontario, Canada, N1R 6V6
- Recruiting
- Cambridge Cardiac Care Centre
-
Cambridge, Ontario, Canada, N1R 7R1
- Recruiting
- Saul Vizel Pro. Med. Corp
-
Guelph, Ontario, Canada, N1H 1B1
- Recruiting
- Dawson Clinical Research
-
Hamilton, Ontario, Canada, L8L 2X2
- Recruiting
- Hamilton Hlth Sc. - General Site
-
London, Ontario, Canada, N6A 4V2
- Recruiting
- St. Joseph's Hospital
-
Newmarket, Ontario, Canada, L3Y 2P6
- Recruiting
- Partnrs Adv Cardio Eval (PACE)
-
North York, Ontario, Canada, M6B 3H7
- Recruiting
- North York Diagn & Cardiac Ctr
-
Oshawa, Ontario, Canada, L1J 2K9
- Recruiting
- Centricity Research Oshawa
-
Peterborough, Ontario, Canada, K9J 0B2
- Recruiting
- Kawartha Cardiology Clinical Trials
-
Sudbury, Ontario, Canada, P3E 5J1
- Recruiting
- Health Sciences North Rsrch Inst
-
Toronto, Ontario, Canada, M6G 1M2
- Recruiting
- Diabetes Heart Research Centre
-
Toronto, Ontario, Canada, M5B 1W8
- Not yet recruiting
- St. Michael's Hospital_Toronto
-
Toronto, Ontario, Canada, M5S 1B1
- Not yet recruiting
- Women's College Hospital
-
Waterloo, Ontario, Canada, N2T 0C1
- Recruiting
- CPS Research
-
Waterloo, Ontario, Canada, N2T 0C1
- Recruiting
- Clinical Research Solutions Inc.
-
Winchester, Ontario, Canada, K0C 2K0
- Recruiting
- Winchester Dist Memorial Hosp
-
-
Quebec
-
Brossard, Quebec, Canada, J4Z-2K9
- Recruiting
- Viacar Recherche Clinique Inc.
-
Montreal, Quebec, Canada, H1T 1C8
- Not yet recruiting
- Institut de Cardiologie de Montreal
-
Montréal, Quebec, Canada, H2X 0C1
- Recruiting
- CHU de Montréal
-
Sherbrooke, Quebec, Canada, J1G 2E8
- Recruiting
- CIUSSS de l'E CHUS_Sherbrooke
-
St. Jean sur Richelieu, Quebec, Canada, J3A 1J2
- Recruiting
- CardioVasc HR Inc
-
Terrebonne, Quebec, Canada, J6X 4P7
- Recruiting
- Ctr de Med Metab de Lanaudiere
-
Terrebonne, Quebec, Canada, J6V 2H2
- Withdrawn
- CISSSL - Hôpital Pierre-Le Gardeur
-
Trois-Rivières, Quebec, Canada, G9A 4P3
- Recruiting
- Diex Recherche Trois-Rivieres
-
-
Saskatchewan
-
Saskatoon, Saskatchewan, Canada, S7N 0W8
- Not yet recruiting
- Royal University Hospital
-
-
-
-
-
Anhui/huainan, China, 232007
- Recruiting
- The First Hospital of Anhui University of Science &Technology (Huainan First People's Hospital)
-
Changsha, China, 410028
- Not yet recruiting
- Changsha Central Hospital
-
Ha Erbin, China, 150001
- Not yet recruiting
- The First Affiliated Hospital Of Harbin Medical University
-
Jingan/Shanghai, China, 200040
- Not yet recruiting
- Huashan Hospital Fudan University
-
Nanjing, China, 210009
- Withdrawn
- Zhongda Hospital, Southeast University
-
Nanning, China, 530021
- Not yet recruiting
- The people's hospital of Guangxi Zhuang Autonomous Region
-
Shanghai, China, 20031
- Not yet recruiting
- Shanghai Xuhui Central Hospital
-
Tianjin, China, 300222
- Not yet recruiting
- Tianjin Chest Hospital
-
Xi'an, China, 710061
- Recruiting
- The First Affiliated Hospital of Xi'an Jiaotong University
-
-
Beijing
-
Beijing, Beijing, China, 100029
- Not yet recruiting
- China-Japan Friendship Hospital
-
Beijing, Beijing, China, 100029
- Recruiting
- Beijing Anzhen Hospital, Capital Medical University
-
-
Chongqing
-
ChongQing, Chongqing, China, 404000
- Not yet recruiting
- Chongqing University Three Gorges Hospital
-
Chongqing, Chongqing, China, 404000
- Recruiting
- Chongqing University Three Gorges Hospital
-
-
Gansu
-
Lanzhou, Gansu, China, 730030
- Recruiting
- Lanzhou University Second Hospital_Internal Medicine-Cardiovascular Dept
-
-
Guangdong
-
Guangzhou, Guangdong, China, 510630
- Not yet recruiting
- The First Affiliated Hospital of Jinan University
-
Guangzhou, Guangdong, China, 510120
- Not yet recruiting
- Sun Yat-sen Memorial Hospital, Sun Yat-sen Universtiy
-
Shenzhen, Guangdong, China, 518020
- Recruiting
- ShenZhen People's Hospital
-
-
Hainan
-
Haikou, Hainan, China, 570311
- Recruiting
- Hainan General Hospital
-
Haikou, Hainan, China, 570311
- Not yet recruiting
- Hainan General Hospital
-
-
Hebei
-
Shijiazhuang, Hebei, China, 050051
- Recruiting
- Hebei General Hospital
-
-
Hubei
-
Wuhan, Hubei, China, 430060
- Not yet recruiting
- Renmin Hospital of Wuhan University
-
-
Hunan
-
Changsha, Hunan, China, 410013
- Recruiting
- The Third Xiangya Hospital of Central South University
-
-
Jiangsu
-
Changzhou, Jiangsu, China, 213003
- Recruiting
- Changzhou No.2 People's Hospital, Yanghu Branch
-
Changzhou, Jiangsu, China, 213003
- Not yet recruiting
- Changzhou No.2 People's Hospital, Yanghu Branch
-
Huai'an, Jiangsu, China, 223300
- Recruiting
- Huai'an First People's Hospital, Nanjing Medical University
-
Nanjing, Jiangsu, China, 210011
- Recruiting
- The Second Affiliated Hospital of Nanjing Medical University
-
Suzhou, Jiangsu, China, 215000
- Recruiting
- The First Affiliated Hospital of Soochow University
-
Suzhou, Jiangsu, China, 215000
- Not yet recruiting
- The First Affiliated Hospital of Soochow University
-
Yangzhou, Jiangsu, China, 225001
- Not yet recruiting
- Northern Jiangsu People's Hospital
-
Yangzhou, Jiangsu, China, 225001
- Recruiting
- Northern Jiangsu People's Hospital
-
Zhenjiang, Jiangsu, China, 212001
- Recruiting
- The Affiliated Hospital of Jiangsu University
-
-
Jilin
-
Changchun, Jilin, China, 130033
- Recruiting
- China-Japan Union Hospital of Jilin University
-
Siping, Jilin, China, 136000
- Recruiting
- Siping Central People's Hospital
-
-
Liaoning
-
Shenyang, Liaoning, China, 110016
- Recruiting
- The People's Hospital of Liaoning Province
-
-
Ningxia
-
Yinchuan, Ningxia, China, 750004
- Recruiting
- General Hospital of Ningxia Medical University
-
-
Shaanxi
-
Xi'an, Shaanxi, China, 710068
- Recruiting
- Shaanxi Provincial People's Hospital
-
-
Shanghai
-
Shanghai, Shanghai, China, 200065
- Recruiting
- Tongji Hospital of Tongji University
-
-
Zhejiang
-
Hangzhou, Zhejiang, China, 310014
- Recruiting
- Zhejiang Provincial People's Hospital
-
Hangzhou, Zhejiang, China, 310003
- Recruiting
- The First Affiliated Hospital, Zhejiang University School of Medicine
-
Lishui, Zhejiang, China, 323000
- Not yet recruiting
- Lishui People's Hospital
-
Lishui, Zhejiang, China, 323000
- Recruiting
- Lishui People's Hospital
-
Wenzhou, Zhejiang, China, 325000
- Recruiting
- The 1st Affiliated Hospital of WMU
-
-
-
-
-
Barranquilla, Colombia, 080020
- Recruiting
- Fundacion del Caribe para la Investigacion Biomedica-BIOS
-
Barranquilla, Colombia, 80020
- Recruiting
- Clinica de la Costa
-
Barranquilla, Colombia, 080020
- Recruiting
- Corazón IPS S.A.S
-
Barranquilla, Colombia, 080020
- Not yet recruiting
- Fundacion del Caribe para la Investigacion Biomedica-BIOS
-
Cali, Colombia, 760042
- Recruiting
- Clinica Imbanco SAS
-
Medellin, Colombia, 050021
- Not yet recruiting
- Promotora Medica Las Americas S.A.
-
Medellin, Colombia, 050034
- Recruiting
- CardiovidCentro Cardiovascular Colombiano ClinicaSantaMaria
-
-
Antioquia
-
Medellin, Antioquia, Colombia, 050015
- Not yet recruiting
- Hospital General de Medellin
-
Medellin, Antioquia, Colombia, 050021
- Not yet recruiting
- Rodrigo Botero S.A.S
-
-
Atlántico
-
Barranquilla, Atlántico, Colombia, 080001
- Recruiting
- IPS Centro Cientifico Asistencial Jose Luis Accini SAS
-
-
Barranquilla
-
Soledad, Barranquilla, Colombia, 83001
- Recruiting
- Fundación Hospital Universidad del Norte
-
Soledad, Barranquilla, Colombia, 83001
- Not yet recruiting
- Fundación Hospital Universidad del Norte
-
-
Caldas
-
Manizales, Caldas, Colombia, 170003
- Recruiting
- IPS médicos Internistas de Caldas S.A.S.
-
-
Santander
-
Bucaramanga-piedecuesta, Valle Del Menzuli - Santander, Santander, Colombia, 681012
- Recruiting
- Unidad de Estudios Clínicos de la Fundación Cardiovascular de Colombia
-
-
-
-
-
Cakovec, Croatia, 40000
- Withdrawn
- Zupanijska bolnica Cakovec
-
Karlovac, Croatia, 47000
- Recruiting
- Opca bolnica Karlovac
-
Karlovac, Croatia, 47000
- Not yet recruiting
- Opca bolnica Karlovac
-
Osijek, Croatia, 31000
- Recruiting
- Clinical Hospital Centre Osijek
-
Rijeka, Croatia, 51000
- Recruiting
- KBC Rijeka, Zavod za kardiomiopatije
-
Split, Croatia, 21000
- Recruiting
- KBC Split
-
Zagreb, Croatia, 10 000
- Withdrawn
- University Hospital Sveti Duh
-
Zagreb, Croatia, 10040
- Recruiting
- Poliklinika Magnolija
-
-
Grad Zagreb
-
Zagreb, Grad Zagreb, Croatia, 10 000
- Recruiting
- University hospital centre Zagreb
-
Zagreb, Grad Zagreb, Croatia, 10000
- Recruiting
- Poliklinika Solmed
-
Zagreb, Grad Zagreb, Croatia, 10 000
- Withdrawn
- Poliklinika Aritmija
-
Zagreb, Grad Zagreb, Croatia, 10000
- Recruiting
- Clinical Hospital Dubrava
-
-
Krapinsko Zagorska County
-
Krapinske Toplice, Krapinsko Zagorska County, Croatia, 49217
- Recruiting
- Specijalna bolnica Krapinske Toplice - Kardiologija
-
-
-
-
-
Hradec Kralove, Czechia, 50005
- Recruiting
- FN Hradec Kralove
-
Liberec, Czechia, 460 02
- Recruiting
- KARDIOLOGIE - LIBEREC s.r.o.
-
Plzen - Lochotín, Czechia, 323 00
- Recruiting
- Fakultni nemocnice Plzen - Lochotin
-
Policka, Czechia, 572 01
- Recruiting
- Policska nemocnice
-
Praha 1, Czechia, 110 00
- Recruiting
- Kardiologicka a interni ambulance
-
Praha 1, Czechia, 110 00
- Not yet recruiting
- Kardiologicka a interni ambulance
-
Praha 2, Czechia, 120 00
- Recruiting
- Fakultní poliklinika VFN ambulance Srdecniho selhani
-
Slany, Czechia, 274 01
- Not yet recruiting
- Nemocnice Slany Kardiologie
-
Slany, Czechia, 274 01
- Recruiting
- Nemocnice Slany Kardiologie
-
Tabor, Czechia, 39003
- Recruiting
- Vseobecna kardiologicka ambulance
-
Tabor, Czechia, 39003
- Not yet recruiting
- Vseobecna kardiologicka ambulance
-
Trutnov, Czechia, 541 01
- Recruiting
- Kardiologie Trutnov Ferkl
-
Uherske Hradiste, Czechia, 68601
- Recruiting
- Clinical Trials Service s.r.o.
-
Uherske Hradiste, Czechia, 68601
- Not yet recruiting
- Clinical Trials Service s.r.o.
-
-
-
-
-
Aarhus N, Denmark, 8200
- Recruiting
- Aarhus Universitetshospital, Skejby Hjertesygdomme
-
Frederiksberg, Denmark, 2000
- Recruiting
- Bispebjerg og Frederiksberg Hospital
-
Roskilde, Denmark, 4000
- Recruiting
- Sjællands Universitetshospital_Roskilde
-
-
Region Hovedstaden
-
Herlev, Region Hovedstaden, Denmark, 2730
- Recruiting
- Herlev og Gentofte Hospital
-
-
Region South
-
Svendborg, Region South, Denmark, 5700
- Recruiting
- Kardiologisk Odense & Svendborg
-
-
-
-
-
Tallinn, Estonia, 13419
- Recruiting
- North Estonia Medical Centre Foundation
-
Tallinn, Estonia, 10138
- Recruiting
- East Tallinn Central Hospital
-
Tartu, Estonia, 50406
- Recruiting
- Tartu University Hospital
-
-
-
-
-
HUS, Finland, 00029
- Not yet recruiting
- HUS, Sydän- ja keuhkokeskus, kardiologian tutkimusyksikkö
-
Jyväskylä, Finland, 40620
- Recruiting
- StudyCor
-
Kuopio, Finland, 70210
- Recruiting
- Health Step Finland Oy
-
Seinäjoki, Finland, 60220
- Recruiting
- Seinäjoen keskussairaala
-
Tampere, Finland, 33520
- Recruiting
- TAYS Sydänsairaala
-
Turku, Finland, 20520
- Recruiting
- TYKS Sydänkeskus
-
-
-
-
-
La Tronche, France, 38700
- Recruiting
- Centre Hospitalier Universitaire Grenoble Alpes-Site Nord Michallon-1
-
Montpellier, France, 34295
- Recruiting
- Centre Hospitalier Universitaire de Montpellier-Hopital Arnaud de Villeneuve
-
Paris, France, 75010
- Not yet recruiting
- Aphp-Hopital Lariboisiere-1
-
Paris, France, 75013
- Not yet recruiting
- Aphp-Hopital La Pitie Salpetriere-1
-
Poitiers, France, 86000
- Not yet recruiting
- Centre Hospitalier Universitaire de Poitiers
-
Poitiers, France, 86000
- Recruiting
- Centre Hospitalier Universitaire de Poitiers
-
Toulouse, France, 31059
- Recruiting
- Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-1
-
-
-
-
-
Aachen, Germany, 52074
- Recruiting
- Universitaetsklinikum Aachen AöR
-
Berlin, Germany, 10787
- Not yet recruiting
- Klinische Forschung Berlin GbR
-
Berlin, Germany, 13353
- Recruiting
- Charite Universitatsmedizin Berlin KöR
-
Berlin, Germany, 13353
- Not yet recruiting
- Charite Universitatsmedizin Berlin KöR
-
Bremen, Germany, 28277
- Recruiting
- Kardiologisch-Angiologische Praxis Herzzentrum Bremen
-
Dortmund, Germany, 44137
- Recruiting
- Kath. St. Paulus GmbH - St Johannes Hospital gGmbH
-
Dresden, Germany, 01307
- Recruiting
- Herzzentrum Dresden GmbH Universitätsklinik
-
Dresden, Germany, 01277
- Recruiting
- Hausaerztlich-Kardiologisches MVZ Am Felsenkeller GmbH
-
Elsterwerda, Germany, 04910
- Recruiting
- Zentrum fuer klinische Studien Suedbrandenburg GmbH
-
Frankfurt, Germany, 60389
- Recruiting
- MVZ CCB Frankfurt Und Main-Taunus GbR
-
Frankfurt am Main, Germany, 60590
- Not yet recruiting
- Universitätsklinikum Frankfurt aM
-
Freiburg, Germany, 79106
- Recruiting
- Medical Center - University Of Freiburg
-
Giessen, Germany, 35392
- Recruiting
- Justus Liebig University Giessen
-
Göttingen, Germany, 37075
- Recruiting
- Universitaetsmedizin Goettingen
-
Hamburg, Germany, 20246
- Recruiting
- University Medical Center Hamburg-Eppendorf
-
Hamburg, Germany, 20251
- Not yet recruiting
- University Medical Center Hamburg-Eppendorf
-
Hassloch, Germany, 67454
- Recruiting
- Kardiologie Hassloch
-
Homburg, Germany, 66424
- Recruiting
- UKS - Innere Medizin III
-
Jena, Germany, 07747
- Recruiting
- University Hospital Jena KöR
-
Kaiserslautern, Germany, 67655
- Recruiting
- Kardiopraxis Schirmer
-
Leipzig, Germany, 04103
- Recruiting
- University of Leipzig
-
Mannheim, Germany, 68165
- Recruiting
- zero PRAXEN Mannheim-Schwetzingerstadt
-
München, Germany, 81377
- Not yet recruiting
- LMU Klinikum München Klinik und Poliklinik 1
-
Papenburg, Germany, 26871
- Not yet recruiting
- Dr. med. A. Wilke, Dr. med. A. Malazhavy und D. Lalev Denchev, Fachaerzte Innere Medizin und Kardiologie Partnerschaft
-
Wermsdorf, Germany, 04779
- Recruiting
- Al-Zoebi
-
Würzburg, Germany, 97078
- Recruiting
- Universitätsklinikum Würzburg AÖR
-
-
-
-
-
Athens, Greece, GR-15125
- Recruiting
- Iatriko Athinon (Athens Medical Canter)
-
Athens, Greece, 11527
- Recruiting
- "Sotiria" Thoracic Diseases Hospital of Athens
-
Athens, Greece, 11527
- Recruiting
- 'G. Gennimatas' General Hospital of Athens
-
Athens, Greece, GR-11527
- Not yet recruiting
- Genl Hospital of Athens Ippokrateio,A' Cardiology Univ dpt
-
Athens, Greece, GR-11527
- Recruiting
- Hippokration Hospital
-
Athens, Greece, GR-14233
- Recruiting
- Konstantopouleio G.H. of Athens, "Agia Olga"
-
Athens, Greece, GR-15123
- Recruiting
- "Hygeia" General Hospital of Athens
-
Chaidari, Athens, Greece, GR-12462
- Recruiting
- U.G.H of Athens "Attikon"
-
Chios, Greece, GR82100
- Recruiting
- General Hospital of Chios "Skilitsio"
-
Larissa, Greece, GR-41110
- Recruiting
- Univ Gen Hospital Larisa, Internal Medicine Clinic
-
Pylea, Thessaloniki, Greece, GR-57001
- Recruiting
- Iatriko Athinon (Athens Medical Canter)
-
Rio Patras, Greece, GR26504
- Recruiting
- General University Hospital of Patras
-
Thessaloniki, Greece, 54635
- Not yet recruiting
- General Hospital of Thessaloniki 'G. Gennimatas
-
Thessaloniki, Greece, 54636
- Recruiting
- "AHEPA" University General Hospital of Thessaloniki
-
Thessaloniki, Greece, 54636
- Not yet recruiting
- "AHEPA" University General Hospital of Thessaloniki
-
Thessaloniki, Greece, GR54642
- Recruiting
- 'Ippokrateio' General Hospital of Thessaloniki
-
-
Attiki
-
Athens, Attiki, Greece, GR11528
- Recruiting
- Alexandra General Hospital, Therapeutic Clinic
-
-
Crete
-
Heraklion, Crete, Greece, GR-71500
- Recruiting
- Periphery University Hospital of Heraklion
-
-
-
-
-
Baja, Hungary, H-6500
- Not yet recruiting
- EURÉKA-CENTER Orvosi és Szolgáltató Betéti Társaság
-
Budapest, Hungary, 1096
- Recruiting
- Gottsegen György Országos Kardiológiai Intézet
-
Budapest, Hungary, 1204
- Not yet recruiting
- Jahn Ferenc Dél-pesti Kórház és Rendelőintézet
-
Budapest, Hungary, 1122
- Recruiting
- Semmelweis Egyetem Városmajori Szív- és Érgyógyászat
-
Budapest, Hungary, 1134
- Not yet recruiting
- Észak-Pesti Centrumkórház Honvédkórház
-
Pécs, Hungary, 7623
- Not yet recruiting
- Coromed SMO Kft.
-
-
Baranya Megye
-
Pécs, Baranya Megye, Hungary, 7624
- Recruiting
- PTE ÁOK I. sz. Belgyógyászati Klinika
-
-
Bács-Kiskun Vármegye
-
Baja, Bács-Kiskun Vármegye, Hungary, 6500
- Recruiting
- Lausmed Kft.
-
-
Békés Megye
-
Békéscsaba, Békés Megye, Hungary, 5600
- Recruiting
- Dr. Lakatos Ferenc Kardiológus ,Belgyógyász Magán szakrendelés
-
Orosháza, Békés Megye, Hungary, 5900
- Recruiting
- Arina Trial Research kft.
-
-
Csongrád-Csanád
-
Szeged, Csongrád-Csanád, Hungary, 6725
- Recruiting
- Szegedi Tudományegyetem II. sz Belgyógyászati és Kardiológia
-
-
Komárom-Esztergom
-
Komárom, Komárom-Esztergom, Hungary, 2921
- Recruiting
- Selye János Kórház
-
-
Somogy Megye
-
Kaposvár, Somogy Megye, Hungary, 7400
- Recruiting
- Somogy Megyei Kaposi Mór Oktató Kórház
-
-
Zala Megye
-
Zalaegerszeg, Zala Megye, Hungary, 8900
- Recruiting
- Léda Platán Magánklinika
-
-
-
-
-
Aligarh, India, 202002
- Not yet recruiting
- Aligarh Muslim University
-
Bengaluru, India, 560054
- Not yet recruiting
- MS Ramaiah
-
Karnataka, India, 590010
- Recruiting
- KLE's Dr. Prabhakar Kore Hospital & Medical Research Centre
-
New Delhi, India, 110055
- Not yet recruiting
- Dr B L Kapur Memorial Hospital
-
New Delhi, India, 110060
- Recruiting
- Sir Ganga Ram Hospital-Cardiology
-
New Delhi, India, 110075
- Withdrawn
- Aakash Healthcare Super Speciality Hospital
-
Palakkad, India, 678013
- Recruiting
- Lakshmi Hospital
-
Puducherry, India, 605006
- Withdrawn
- JIPMER
-
-
Andhra Pradesh
-
Guntur, Andhra Pradesh, India, 522001
- Recruiting
- Lalitha Super Specialities Hospital
-
Guntur, Andhra Pradesh, India, 522001
- Not yet recruiting
- Lalitha Super Specialities Hospital
-
Vijayawada, Andhra Pradesh, India, 520008
- Recruiting
- Ramesh Hospitals
-
Vijaywada, Andhra Pradesh, India, 520008
- Not yet recruiting
- Siddhartha Medical College & Government General Hospital
-
-
Assam
-
Guwahati, Assam, India, 781006
- Not yet recruiting
- GNRC Hospital
-
-
Delhi
-
New Delhi, Delhi, India, 110002
- Recruiting
- G B Pant Institute of Postgraduate Medical Education and Research
-
New Delhi, Delhi, India, 110025
- Not yet recruiting
- Fortis Escorts Heart Institute, New Delhi
-
New Delhi, Delhi, India, 110029
- Not yet recruiting
- All India Institute of Medical Sciences (AIIMS)
-
-
Gujarat
-
Ahmedabad, Gujarat, India, 380060
- Recruiting
- CIMS- Care Institute of Medical Sciences
-
Ahmedabad, Gujarat, India, 380060
- Recruiting
- Epic Hospital
-
Ahmedabad, Gujarat, India, 38006
- Recruiting
- Sardar Vallabhbhai Patel Institute of Medical Sciences and Research
-
Surat, Gujarat, India, 395002
- Recruiting
- Nirmal Hospital Pvt. Ltd.
-
Surat, Gujarat, India, 395001
- Recruiting
- Shri B. D. Mehta Mahavir Heart Institute
-
Vadodara, Gujarat, India, 390022
- Recruiting
- Rhythm Heart Institute
-
-
Haryana
-
Gurugram, Haryana, India, 122001
- Recruiting
- Medanta - The Medicity Multi-Speciality Hospital, Gurugram
-
-
Karnataka
-
Bangalore, Karnataka, India, 560017
- Withdrawn
- Manipal Hospital, Old Airport Road, Bengaluru
-
Bengaluru, Karnataka, India, 560069
- Not yet recruiting
- Sri Jayadeva Institute of Cardiovascular Sciences & Research
-
Bengaluru, Karnataka, India, 560099
- Not yet recruiting
- Narayana Institute of Cardiac Sciences, Bangalore
-
-
Kerala
-
Cochin, Kerala, India, 682041
- Recruiting
- Amrita Institute of Medical Sciences
-
Kochi, Kerala, India, 682018
- Recruiting
- Lisie Hospital
-
Kozhikode, Kerala, India, 673008
- Withdrawn
- Government Medical College, Kozhikode
-
-
Maharashtra
-
Mumbai, Maharashtra, India, 400012
- Withdrawn
- Seth GS medical college and KEM Hospital
-
Nagpur, Maharashtra, India, 440003
- Not yet recruiting
- Government Medical College and Super Speciality Hospital, Nagpur
-
Nagpur, Maharashtra, India, 440010
- Recruiting
- Arneja Heart & Multispeciality Hospital
-
Nagpur, Maharashtra, India, 440012
- Not yet recruiting
- Shri Krishna Hrudayalaya & Critical Care Centre
-
Nagpur, Maharashtra, India, 440033
- Not yet recruiting
- Sengupta Hospital and Research Institute
-
Pune, Maharashtra, India, 411011
- Recruiting
- KEM hospital
-
Pune, Maharashtra, India, 411004
- Recruiting
- Sahyadri Clinical Research and Development Center
-
Pune, Maharashtra, India, 411001
- Not yet recruiting
- B J Goverment Medical College and Sassoon General Hospital
-
Pune, Maharashtra, India, 411001
- Withdrawn
- Jehangir Clinical Development Centre
-
-
New Delhi
-
New Dehli, New Delhi, India, 110029
- Recruiting
- VMMC & Safdarjung Hospital
-
-
Punjab
-
Chandigarh, Punjab, India, 160012
- Not yet recruiting
- Post Graduate Institute of Medical Education & Research_Chandigarh
-
Ludhiana, Punjab, India, 141001
- Recruiting
- Dayanand Medical College & Hospital
-
Ludhiana, Punjab, India, 141002
- Not yet recruiting
- Deep Hospital
-
Mohali, Punjab, India, 160062
- Not yet recruiting
- Fortis Hospital, Mohali
-
-
Rajasthan
-
Bikaner, Rajasthan, India, 334003
- Not yet recruiting
- S.P. Medical College and A.G. Hospitals
-
Jaipur, Rajasthan, India, 302001
- Recruiting
- SMS Medical College & Attached Hospitals
-
Jodhpur, Rajasthan, India, 342005
- Recruiting
- All India Institute of Medical Sciences (AIIMS), Jodhpur
-
Jodhpur, Rajasthan, India, 342005
- Withdrawn
- All India Institute of Medical Sciences (AIIMS)
-
-
Tamil Nadu
-
Chennai, Tamil Nadu, India, 600037
- Recruiting
- The Madras Medical Mission
-
-
Telangana
-
Hyderabad, Telangana, India, 500032
- Not yet recruiting
- AIG Hospitals,Hyderabad
-
Hyderabad, Telangana, India, 500020
- Not yet recruiting
- Guru Nanak CARE Hospitals
-
-
Telengana
-
Hyderabad, Telengana, India, 500 012
- Recruiting
- Osmania General Hospital
-
-
Uttar Pradesh
-
Lucknow, Uttar Pradesh, India, 226003
- Not yet recruiting
- King George's Medical University (KGMU)
-
-
Uttarakhand
-
Dehradun, Uttarakhand, India, 248001
- Recruiting
- Shri Mahant Indiresh Hospital
-
-
West Bengal
-
Kolkata, West Bengal, India, 700020
- Withdrawn
- IPGME&R and SSKM Hospital
-
-
-
-
-
Cork, Ireland, T12 DC4A
- Withdrawn
- Cork University Hospital
-
Dublin, Ireland, A96 D628
- Recruiting
- The Heartbeat Trust
-
Dublin, Ireland, D07 KX5K
- Not yet recruiting
- Mater Miscericordiae Hospital
-
Dublin, Ireland, D07KWR1
- Not yet recruiting
- Mater Private Network - Dublin
-
Mahon, Cork, Ireland, T12 K199
- Not yet recruiting
- Mater Private Network Cork
-
-
Leinster
-
Dublin, Leinster, Ireland, D08 A978
- Withdrawn
- St James's CRF
-
-
-
-
-
Haifa, Israel, 3109601
- Recruiting
- Heart failure unit Rambam Medical center
-
Jerusalem, Israel, 91120
- Recruiting
- Hadassah Ein Kerem MC - Cardio
-
Petah-Tikva, Israel, 49100
- Recruiting
- Heart Failure Unit, Rabin Medical Center - Beilinson Campus
-
Rehovot, Israel, 76100
- Recruiting
- Kaplan Medical Center
-
Tel Aviv, Israel, 6423906
- Recruiting
- Cardio Vascular Research Center Sourasky MC
-
Tel Hashomer, Israel, 5265601
- Recruiting
- Sheba Medica Center - Clinical Research Unit
-
Zrifin, Israel, 70300
- Recruiting
- Shamir (Assaf Harofe) Medical Center
-
-
-
-
-
Foggia, Italy, 71122
- Recruiting
- Ospedali Riuniti di Foggia
-
Milano, Italy, 20157
- Not yet recruiting
- ASST Fatebenefratelli Ospedale Luigi Sacco Medicina Interna
-
Monza, Italy, 20900
- Not yet recruiting
- Azienda Ospedaliera San Gerardo
-
Napoli, Italy, 80131
- Not yet recruiting
- Azienda Ospedaliera di Rilievo Nazionale AORN Dei Colli, "V.Monaldi",
-
Novara, Italy, 28100
- Recruiting
- Azienda Ospedaliero-Universitaria Maggiore della Carità di Novara
-
Pavia, Italy, 27100
- Recruiting
- Fondazione IRCCS Policlinico San Matteo
-
Pavia, Italy, 27100
- Not yet recruiting
- Fondazione IRCCS Policlinico San Matteo
-
Trieste, Italy, 34128
- Recruiting
- Azienda Sanitaria Univ Giuliano Isontina
-
Trieste, Italy, 34128
- Not yet recruiting
- Azienda Sanitaria Univ Giuliano Isontina
-
-
Al
-
Casale Monferrato, Al, Italy, 15033
- Recruiting
- Ospedale Santo Spirito
-
-
Bg
-
Bergamo, Bg, Italy, 24127
- Recruiting
- ASST Papa Giovanni XXIII
-
-
Bn
-
Benevento, Bn, Italy, 82100
- Not yet recruiting
- AORN "San Pio"- Benevento
-
-
Bs
-
Brescia, Bs, Italy, 25123
- Recruiting
- Spedali Civili Brescia
-
-
Ce
-
Caserta, Ce, Italy, 81100
- Not yet recruiting
- AORN "Sant'Anna e San Sebastiano"
-
-
Cz
-
Catanzaro, Cz, Italy, 88100
- Recruiting
- Azienda Ospedaliero-Universitaria Renato Dulbecco
-
-
Fe
-
Cona (Ferrara), Fe, Italy, 44124
- Recruiting
- A.O.U. Ferrara, Sant'Anna
-
Cona (Ferrara), Fe, Italy, 44124
- Not yet recruiting
- A.O.U. Ferrara, Sant'Anna
-
-
Ge
-
Genova, Ge, Italy, 16132
- Recruiting
- IRCCS Azienda Ospedaliero Universitaria San Martino - IST
-
-
Pg
-
Perugia, Pg, Italy, 06129
- Recruiting
- Azienda Ospedaliera di Perugia;Ospedale S. Maria della Miser
-
-
Pi
-
Pisa, Pi, Italy, 56124
- Recruiting
- Fondazione CNR-Regione Toscana Gabriele Monasterio
-
Pisa, Pi, Italy, 56126
- Recruiting
- Fondazione CNR-Regione Toscana Gabriele Monasterio
-
-
Rm
-
Roma, Rm, Italy, 00135
- Recruiting
- Ospedale San Filippo Neri
-
-
Si
-
Siena, Si, Italy, 53100
- Recruiting
- Azienda Ospedaliera Universitaria Senese
-
-
To
-
Rivoli, To, Italy, 10098
- Recruiting
- Presidio Ospedaliero di Rivoli
-
Torino, To, Italy, 10128
- Recruiting
- Azienda Sanitaria Ospedaliera Ordine Mauriziano SC Cardiologia
-
Torino, To, Italy, 10128
- Not yet recruiting
- Azienda Sanitaria Ospedaliera Ordine Mauriziano SC Cardiologia
-
-
Vr
-
Verona, Vr, Italy, 37126
- Recruiting
- AOUI Verona
-
Verona, Vr, Italy, 37126
- Not yet recruiting
- AOUI Verona
-
-
-
-
-
Bunkyo-ku, Tokyo, Japan, 113-8655
- Recruiting
- The Univ. of Tokyo Hp., Dept. of Cardiovascular Medicine
-
Fukuoka, Japan, 810-8539
- Recruiting
- Hamanomachi Hospital_Cardiovascular medicine
-
Fukuoka, Japan, 812-8582
- Not yet recruiting
- Kyushu University Hospital_Cardiovascular Medicine
-
Fukuoka, Japan, 812-8582
- Recruiting
- Kyushu University Hospital_Cardiovascular Medicine
-
Fukuoka-shi, Fukuoka, Japan, 814-0133
- Not yet recruiting
- Fukuoka University Hospital_Cardiology
-
Gifu, Japan, 503-8502
- Recruiting
- Ogaki Municipal Hospital_Cardiology
-
Hamamatsu-shi, Shizuoka, Japan, 430-0929
- Recruiting
- JA Shizuoka Kohseiren Enshu Hospital_ cardiology
-
Himeji-shi, Hyogo, Japan, 670-8560
- Recruiting
- Hyogo Prefectural HarimaHimeji General Medical Center_Cardiology
-
Hokkaido, Japan, 078-8211
- Recruiting
- Asahikawa-Kosei General Hospital_Cardiology
-
Hyogo, Japan, 665-0125
- Recruiting
- Veritas Hospital_Cardiology
-
Ibaraki, Japan, 311-3193
- Recruiting
- National Hospital Organization Mito Medical Center_Cardiovascular medicine
-
Imabari-shi, Ehime, Japan, 799-1592
- Recruiting
- Saiseikai Imabari Hospital
-
Ishikawa, Japan, 920-8530
- Recruiting
- Ishikawa Prefectural Central Hospital_Cardiology
-
Ishikawa, Japan, 920-8530
- Not yet recruiting
- Ishikawa Prefectural Central Hospital_Cardiology
-
Kagawa, Japan, 769-1695
- Recruiting
- Mitoyo General Hospital_Cardiovascular medicine
-
Kagoshima, Japan, 890-8760
- Recruiting
- Kagoshima City Hospital_Cardiovascular Medicine
-
Kanagawa, Japan, 236-0037
- Not yet recruiting
- Yokohama Minami Kyousai Hospital_Cardiology
-
Kanagawa, Japan, 236-0051
- Withdrawn
- Kanagawa Prefectural Hospital Organization Kanagawa Cardiovascular and Respiratory Center_Cardiology
-
Kanagawa, Japan, 236-0051
- Not yet recruiting
- Kanagawa Prefectural Hospital Organization Kanagawa Cardiovascular and Respiratory Center_Cardiology
-
Kanagawa, Japan, 259-1193
- Not yet recruiting
- Tokai University Hospital_Cardiology
-
Kishiwada-shi, Osaka, Japan, 596-0042
- Recruiting
- Kishiwada Tokushukai Hospital
-
Kitakyushu-shi, Fukuoka, Japan, 806-8501
- Recruiting
- Japan Community Health care Organization Kyushu Hospital_Cardiology
-
Kyoto, Japan, 606-8507
- Recruiting
- Kyoto University Hospital
-
Kyoto, Japan, 604-8401
- Recruiting
- Rakuwakai Marutamachi Hospital_Cardiology
-
Mie, Japan, 510-8561
- Recruiting
- Mie Prefectural General Medical Center_Cardiology
-
Miyagi, Japan, 980-0803
- Recruiting
- KKR Tohoku Kosai Hospital_Cardiology
-
Miyagi, Japan, 983-8512
- Recruiting
- Tohoku Medical and Pharmaceutical University Hospital_Division of Cardiology
-
Miyagi, Japan, 983-8520
- Recruiting
- National Hospital Organization Sendai Medical Center_Cardiovascular medicine
-
Morioka-shi, Iwate, Japan, 020-0066
- Recruiting
- Iwate Prefectural Central Hospital
-
Nagasaki, Japan, 850-8555
- Recruiting
- Nagasaki Harbor Medical Center_Cardiovascular medicine
-
Okayama, Japan, 700-8557
- Recruiting
- Okayama City General Medical Center Okayama City Hospital_Cardiovascular Medicine
-
Okayama, Japan, 701-1154
- Recruiting
- Okayama Medical Center
-
Okayama-shi, Okayama, Japan, 700-8558
- Not yet recruiting
- Okayama University Hospital_Cardiovascular Medicine
-
Okayama-shi, Okayama, Japan, 700-8558
- Recruiting
- Okayama University Hospital_Cardiovascular Medicine
-
Osaka, Japan, 581-0011
- Recruiting
- Yao Tokushukai General Hospital
-
Osaka, Japan, 540-0006
- Recruiting
- National Hospital Organization Osaka National Hospital_Cardiovascular Division
-
Osaka, Japan, 564-0013
- Recruiting
- Saiseikai Suita Hospital_Cardiovascular Medicine
-
Osaka, Japan, 565-0871
- Recruiting
- Osaka University Hospital_Cardiovascular medicine
-
Osaka, Japan, 564-8565
- Recruiting
- National Cerebral and Cardiovascular Center Hospital_Department of Heart Failure
-
Saga, Japan, 840-8571
- Recruiting
- Saga-ken Medical Centre Koseikan_Cardiology
-
Shizuoka, Japan, 436-8555
- Recruiting
- Chutoen General Medical Center_Cardiology
-
Takamatsu-shi, Kagawa, Japan, 760-8557
- Recruiting
- Kagawa Prefectural Central Hospital, Cardiovascular Medicine
-
Tokyo, Japan, 103-0027
- Recruiting
- Tokyo-Eki Center-building Clinic
-
Tokyo, Japan, 113-8431
- Not yet recruiting
- Juntendo University Hospital_Cardiology
-
Tokyo, Japan, 140-8522
- Recruiting
- Tokyo Shinagawa Hospital Social Medical Corporation Association Tokyokyojuno-kai
-
Tokyo, Japan, 160-8582
- Not yet recruiting
- Keio University Hospital_Cardiology
-
Tottori, Japan, 683-8504
- Recruiting
- Tottori University Hospital_Cardiovascular Medicine
-
Toyama, Japan, 930-0194
- Recruiting
- Toyama University Hospital_Internal Medicine 2
-
Yamaguchi, Japan, 740-8510
- Recruiting
- National Hospital Organization Iwakuni Clinical Center_Cardiovascular Medicine
-
Yamaguchi, Japan, 745-8522
- Recruiting
- Japan Community Health care Organization Tokuyama Community Health Center_Department of Cardiology
-
Yokohama-shi, Kanagawa, Japan, 234-0054
- Recruiting
- Saiseikai Yokohamashi Nanbu Hospital_Cardiology
-
-
Ehime, Uwajima-shi
-
Uwajima-shi, Ehime, Ehime, Uwajima-shi, Japan, 798-8510
- Recruiting
- Uwajima City Hospital_ Cardiology
-
-
Kanagawa
-
Yokohama, Kanagawa, Japan, 227-8501
- Recruiting
- Showa University Fujigaoka Hospital_Cardiology
-
-
-
-
-
Busan, Korea, Republic of, 49241
- Recruiting
- Pusan National University Hospital
-
Cheongju, Korea, Republic of, 28644
- Recruiting
- Chungbuk National University Hospital
-
Gwangju, Korea, Republic of, 61469
- Recruiting
- Chonnam National University Hospital
-
Gyeonggi-do, Korea, Republic of, 13620
- Recruiting
- Seoul National University Bundang Hospital
-
Incheon, Korea, Republic of, 21565
- Recruiting
- Gachon University Gil Medical Center
-
Seoul, Korea, Republic of, 08308
- Recruiting
- Korea University Guro Hospital
-
Seoul, Korea, Republic of, 03080
- Recruiting
- Seoul National University Hospital
-
Seoul, Korea, Republic of, 06351
- Recruiting
- Samsung Medical Center
-
Seoul, Korea, Republic of, 03722
- Recruiting
- Severance Hospital, Yonsei University Health System
-
Wonju, Korea, Republic of, 26426
- Recruiting
- Wonju Severance Christian Hospital
-
-
-
-
-
Jelgava, Latvia, LV-3001
- Not yet recruiting
- Zemgales diabetes centre
-
Riga, Latvia, LV-1002
- Recruiting
- P. Stradins Clinical University Hospital
-
Riga, Latvia, LV-1001
- Recruiting
- Riga 1st Hospital
-
Riga, Latvia, LV-1023
- Recruiting
- GK Neiroklinika
-
Riga, Latvia, LV-1079
- Recruiting
- Riga East Clinical University Hospital - Clinic "Gailezers"
-
Riga, Latvia, LV1011
- Recruiting
- Adoria
-
-
-
-
-
Kaunas, Lithuania, 49449
- Recruiting
- JSC "Saules seimos medicinos centras"
-
Kaunas, Lithuania, LT-49387
- Recruiting
- Klinikiniai sprendimai, Kaunas
-
Klaipeda, Lithuania, LT-92288
- Not yet recruiting
- Klaipeda University Hospital
-
Siauliai, Lithuania, LT-76206
- Not yet recruiting
- Republican Siauliai Hospital Consulting Outpatient Clinic
-
Vilnius, Lithuania, LT-08661
- Not yet recruiting
- Vilnius University hospital Santaros klinikos
-
Vilnius, Lithuania, LT-08406
- Recruiting
- JSC Inlita Santaros
-
-
-
-
-
Alor Setar, Malaysia, 05460
- Recruiting
- Hospital Sultanah Bahiyah
-
Kuala Lumpur, Malaysia, 56000
- Recruiting
- Hospital Universiti Kebangsaan Malaysia
-
-
Kelantan
-
Kota Bharu, Kelantan, Malaysia, 16150
- Recruiting
- Hospital Universiti Sains Malaysia
-
-
Kuala Lumpur
-
Cheras, Kuala Lumpur, Malaysia, 56000
- Not yet recruiting
- Hospital Universiti Kebangsaan Malaysia
-
-
Pahang
-
Kuantan, Pahang, Malaysia, 25100
- Recruiting
- Hospital Tengku Ampuan Afzan
-
-
Sarawak
-
Kota Samarahan, Sarawak, Malaysia, 94300
- Recruiting
- Sarawak Heart Centre
-
-
Selangor
-
Sungai Buloh, Selangor, Malaysia, 47000
- Recruiting
- Universiti Teknologi MARA, Sungai Buloh Campus
-
-
Wilayah Persekutuan Kuala Lumpur
-
Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur, Malaysia, 59100
- Recruiting
- University Malaya Medical Centre
-
-
-
-
-
Mexico City, Mexico, 03100
- Not yet recruiting
- Centro de Investigación Biomédica y Farmacéutica S.C.
-
-
Ags
-
Aguascalientes, Ags, Mexico, 20230
- Recruiting
- Hospital Cardiologica Aguascalientes
-
Aguascalientes, Ags, Mexico, 20230
- Not yet recruiting
- Hospital Cardiologica Aguascalientes
-
-
Baja California
-
Tijuana, Baja California, Mexico, 22500
- Recruiting
- CINCAME
-
-
Jalisco
-
Guadalajara, Jalisco, Mexico, 44130
- Recruiting
- Diseño y Planeacion en Investigacion Medica S.C.
-
-
México, D.F.
-
Ciudad de Mexico, México, D.F., Mexico, 14080
- Recruiting
- Instituto Nacional de Cardiologia Ignacio Chavez
-
-
NL
-
San Nicolas de los Garza, NL, Mexico, 66465
- Recruiting
- Centro de Investigación y Control Metabólico S. C.
-
-
Nuevo Leon
-
Monterrey, Nuevo Leon, Mexico, 64060
- Recruiting
- Cardiolink Clin Trials S.C.
-
Monterrey, Nuevo Leon, Mexico, 64060
- Not yet recruiting
- Cardiolink Clin Trials S.C.
-
Monterrey, Nuevo Leon, Mexico, 64718
- Recruiting
- Eukarya Pharmasite S.C.
-
-
Nuevo León
-
Monterrey, Nuevo León, Mexico, 64020
- Recruiting
- Internal Medicine Clin Trials
-
-
Querétaro
-
Santiago De Querétaro, Qro., Querétaro, Mexico, 76000
- Recruiting
- Centro de Estudios Clínicos de Querétaro S.C.
-
Santiago De Querétaro, Qro., Querétaro, Mexico, 76000
- Not yet recruiting
- Centro de Estudios Clínicos de Querétaro S.C.
-
-
San Luis Potosi
-
San Luis Potosí, San Luis Potosi, Mexico, 78200
- Recruiting
- Centro de atención e investigación cardiovascular del Potosí
-
-
Sinaloa
-
Culiacán, Sinaloa, Mexico, 80230
- Recruiting
- Centro para el Desarrollo de la Medicina y la Asistencia
-
-
Veracruz
-
Xalapa, Veracruz, Mexico, 91193
- Recruiting
- Hospital Ángeles de Xalapa
-
Xalapa, Veracruz, Mexico, 91193
- Not yet recruiting
- Hospital Ángeles de Xalapa
-
-
-
-
-
Amsterdam, Netherlands, 1091 AC
- Not yet recruiting
- OLVG Oost
-
Den Haag, Netherlands, 2545AA
- Recruiting
- Haga ziekenhuis
-
Deventer, Netherlands, 7416 SE
- Recruiting
- Deventer Ziekenhuis
-
Dordrecht, Netherlands, 3318 AT
- Recruiting
- Albert Schweitzer Ziekenhuis locatie Dordwijk
-
Emmen, Netherlands, 7824 AA
- Recruiting
- TREANT Zorggroep
-
Enschede, Netherlands, 7512 KZ
- Recruiting
- Medisch Spectrum Twente
-
Groningen, Netherlands, 9713 GZ
- Recruiting
- UMC Groningen
-
Heerlen, Netherlands, 6419 PC
- Recruiting
- Zuyderland Ziekenhuis
-
Maastricht, Netherlands, 6229 HX
- Recruiting
- Maastricht Universitair Medisch Centrum
-
Nijmegen, Netherlands, 6525 GA
- Withdrawn
- Radboudumc
-
Rotterdam, Netherlands, 3015 GD
- Recruiting
- Erasmus MC
-
-
-
-
-
Skopje, North Macedonia, 1000
- Recruiting
- PHI City General Hospital 8th September
-
Skopje, North Macedonia, 1000
- Recruiting
- PHI University Clinic for Cardiology
-
-
-
-
-
Bergen, Norway, 5021
- Recruiting
- Haukeland Universitetssykehus
-
Lørenskog, Norway, 1478
- Recruiting
- Akershus Universitetssykehus HF
-
Oslo, Norway, 0372
- Recruiting
- Rikshospitalet - Kardiologisk forskning
-
Oslo, Norway, 0450
- Recruiting
- Oslo universitetssykehus HF - Ullevål
-
Oslo, Norway, 0369
- Recruiting
- Colosseumklinikken Medisinske Senter AS
-
Stavanger, Norway, NO-4011
- Recruiting
- Stavanger Universitetssykehus, Helse Stavanger HF
-
-
-
-
-
Belchatow, Poland, 97-400
- Not yet recruiting
- American Heart of Poland S.A.
-
Gdynia, Poland, 81-157
- Recruiting
- Ind. Prak. Lek. w dziedz. Kardiologii lek. med. K. Cymerman
-
Grodzisk Mazowiecki, Poland, 05-825
- Recruiting
- Samodzielny Publiczny Specjalistyczny Szpital Zachodni Im.Sw.Jana Pawla II
-
Krakow, Poland, 30-082
- Not yet recruiting
- Specjalistyczna Praktyka Lekarska L. Bryniarski
-
Krakow, Poland, 31-271
- Recruiting
- UniCardia & UniMedica & UniEstetica
-
Lodz, Poland, 93-338
- Recruiting
- Instytut Centrum Zdrowia Matki Polki
-
Lodz, Poland, 91-347
- Not yet recruiting
- Wojewódzki Specjalistyczny Szpital im.Wl. Bieganskiego,
-
Przemysl, Poland, 37-700
- Recruiting
- Wojewodzki Szpital Im. Sw.Ojca Pio W Przemyslu
-
Sztum, Poland, 82-400
- Recruiting
- American Heart of Poland S.A.
-
Warszawa, Poland, 04-141
- Recruiting
- Wojskowy Instytut Medyczny
-
-
Dolnoslaskie
-
Wroclaw, Dolnoslaskie, Poland, 50-556
- Recruiting
- Uniwersytecki Szpital Kliniczny im. J.Mikulicza-Radeckiego
-
Wroclaw, Dolnoslaskie, Poland, 51-134
- Recruiting
- Zdrowie S.C. Agnieszka I Donald Drożdż
-
Wroclaw, Dolnoslaskie, Poland, 50-981
- Recruiting
- 4 Wojskowy Szpital Kliniczny Z Poliklinika Samodzielny Publiczny Zaklad Opieki Zdrowotnej We Wroclawiu
-
-
Kujawsko-pomorskie
-
Włocławek, Kujawsko-pomorskie, Poland, 87-800
- Recruiting
- Praktyka Lekarska-Tomasz Borkowski
-
-
Kuyavian-Pomeranian Voivodeship
-
Torun, Kuyavian-Pomeranian Voivodeship, Poland, 87-100
- Recruiting
- Wojewodzki Szpital Zespolony Im.L.Rydygiera W Toruniu
-
-
Lodzkie
-
Belchatow, Lodzkie, Poland, 97-400
- Recruiting
- American Heart of Poland S.A.
-
Lodz, Lodzkie, Poland, 90-549
- Recruiting
- Uniwersytecki Szpital Kliniczny Im Wojskowej Akademii Medycznej Centralny Szpital Weteranow
-
-
Mazowieckie
-
Warszawa, Mazowieckie, Poland, 00-416
- Recruiting
- Samodzielny Publiczny Szpital Kliniczny Im. Prof. W. Orłowskiego Centrum Medycznego Kształcenia Podyplomowego
-
-
Małopolskie
-
Chrzanów, Małopolskie, Poland, 32-500
- Recruiting
- American Heart of Poland S.A.
-
Cracow, Małopolskie, Poland, 30-701
- Recruiting
- MediNess Sp. z o.o.
-
Cracow, Małopolskie, Poland, 30-701
- Not yet recruiting
- MediNess Sp. z o.o.
-
-
Podlaskie
-
Bialystok, Podlaskie, Poland, 15-276
- Recruiting
- Uniwersytecki Szpital Kliniczny w Bialymstoku K. Kardio
-
-
Podlaskie Voivodeship
-
Bialystok, Podlaskie Voivodeship, Poland, 15-111
- Recruiting
- Panek Med Centrum Leczenia Chorob Naczyn
-
-
Silesian Voivodeship
-
Katowice, Silesian Voivodeship, Poland, 40-635
- Recruiting
- Gornoslaskie Centrum Medyczne Im Prof. Leszka Gieca Sląskiego Uniwersytetu Medycznego W Katowicach
-
Ruda Slaska, Silesian Voivodeship, Poland, 41-710
- Recruiting
- AKA-MED Centrum
-
-
Slaskie
-
Zabrze, Slaskie, Poland, 41-800
- Not yet recruiting
- Slaskie Centrum Chorob Serca W Zabrzu
-
-
Łódź Voivodeship
-
Zgierz, Łódź Voivodeship, Poland, 95-100
- Recruiting
- American Heart of Poland S.A.
-
-
Śląskie
-
Dąbrowa Górnicza, Śląskie, Poland, 41-300
- Recruiting
- American Heart of Poland S.A.
-
Katowice, Śląskie, Poland, 40-648
- Recruiting
- Pro Familia Altera Sp. z o.o.
-
Tychy, Śląskie, Poland, 43-100
- Recruiting
- American Heart of Poland S.A.
-
-
-
-
-
Guilhufe - Penafiel, Portugal, 4560-136
- Recruiting
- CHTâmega e Sousa - Hospital Padre Américo
-
Lisboa, Portugal, 1500-650
- Recruiting
- Hospital Da Luz
-
Lisboa, Portugal, 1649-035
- Recruiting
- Centro Hospitalar Lisboa Norte
-
Lisbon, Portugal, 1449-005
- Recruiting
- CHLO, EPE - Hospital São Francisco Xavier
-
Porto, Portugal, 4099-001
- Recruiting
- Centro Hospitalar do Porto, E.P.E
-
Setubal, Portugal, 2910-446
- Recruiting
- Centro Hospitalar de Setubal
-
-
-
-
-
Baia Mare, Romania, 430222
- Recruiting
- Cabinet Medical de Cardiologie Dr. Calin Pop
-
Braila, Romania, 810325
- Recruiting
- Spitalul Județean de Urgență Brăila
-
Brasov, Romania, 500283
- Recruiting
- Centrul Medical de Diagnostic si Tratament Ambulatoriu Neomed
-
Bucharest, Romania, 021875
- Recruiting
- Davius Clinicmed Srl
-
Bucuresti, Romania, 050098
- Recruiting
- Spitalul Universitar de Urgență București
-
Bucuresti, Romania, 011053
- Recruiting
- Hightech Medical Services S.R.L.
-
Bucuresti, Romania, 011461
- Recruiting
- Spitalul Universitar de Urgenta Elias
-
Bucuresti, Romania, 012292
- Recruiting
- Lotus Med SRL
-
Bucuresti, Romania, 014146
- Not yet recruiting
- Centrul Medical Emerald
-
Bucuresti, Romania, 020339
- Recruiting
- Donna Medplus S.R.L.
-
Bucuresti, Romania, 021337
- Not yet recruiting
- Ecocard Srl
-
Bucuresti, Romania, 042122
- Recruiting
- Spitalul Clinic de Urgenta "Sf. Ioan" Bucuresti
-
Bucuresti, Romania, 021337
- Recruiting
- Ecocard Srl
-
Buzau, Romania, 120133
- Recruiting
- Mat Cord Biomedica S.R.L.
-
Constanta, Romania, 900591
- Recruiting
- Spitalul Clinic Judetean De Urgenta Sfantul Apostol Andrei Constanta
-
Craiova, Romania, 200383
- Recruiting
- Neurocord Medical SRL
-
Craiova, Romania, 200383
- Not yet recruiting
- Neurocord Medical SRL
-
Craiova, Romania, 200513
- Recruiting
- Cardiomed SRL
-
Galati, Romania, 800291
- Recruiting
- SC Diamed Obesity SRL
-
Iasi, Romania, 700503
- Recruiting
- Institutul de Boli Cardiovasculare "Prof. Dr. George I.M. Georgescu"
-
Iasi, Romania, 700547
- Recruiting
- SC Consultmed SRL
-
Iasi, Romania, 700732
- Not yet recruiting
- SC Cardiomed SRL
-
Pascani, Romania, 705200
- Recruiting
- Bella Praxis S.R.L.
-
Pitesti, Romania, 110424
- Recruiting
- SC Sal Med SRL
-
Targu Mures, Romania, 540136
- Recruiting
- Spitalul Clinic Judetean de Urgenta Targu Mures
-
Timisoara, Romania, 300310
- Recruiting
- Institutul de Boli Cardiovasculare Timișoara
-
Timișoara, Romania, 300254
- Recruiting
- Spitalul Clinic Municipal de Urgenta Timisoara
-
-
Targu Mures
-
Tirgu Mures, Targu Mures, Romania, 540143
- Recruiting
- CMI Dr. Cristian Podoleanu
-
-
-
-
-
Belgrade, Serbia, 11080
- Recruiting
- Clinical Hospital Center Bezanijska Kosa
-
Belgrade, Serbia, 11080
- Recruiting
- Clinical Hospital Centre Zemun
-
Belgrade, Serbia, 11000
- Recruiting
- Clinical centre of Serbia, Clinic for cardiology
-
Belgrade, Serbia, 11000
- Recruiting
- Clinical Centre of Serbia, Emergency Centre, Department of Cardiology
-
Belgrade, Serbia, 11000
- Recruiting
- Institute for Cardiovascular Diseases ''Dedinje''
-
Belgrade, Serbia, 11000
- Recruiting
- Emergency Internal Medicine Clinic
-
Kragujevac, Serbia, 34000
- Recruiting
- University Clinical Centre Kragujevac
-
Nis, Serbia, 18108
- Recruiting
- University Clinical Centre Nis, Clinic for Cardiology
-
Sremska Kamenica, Serbia, 21204
- Recruiting
- Institute for Cardiovascular Diseases of Vojvodina - Sremska Kamenica
-
-
-
-
-
Singapore, Singapore, 169609
- Recruiting
- National Heart Centre Singapore
-
Singapore, Singapore, 529889
- Recruiting
- Changi General Hospital
-
Singapore, Singapore, 768828
- Recruiting
- Khoo Teck Puat Hospital
-
Singapore, Singapore, 544886
- Recruiting
- Sengkang General Hospital
-
Singapore, Singapore, 119074
- Recruiting
- National University Hospital Singapore
-
-
-
-
-
Bratislava, Slovakia, 84108
- Recruiting
- KARDIO-SANUS, spol. s r.o.
-
Bratislava, Slovakia, 833 48
- Not yet recruiting
- Narodny ustav srdcovych a cievnych chorob, a.s.
-
Kosice, Slovakia, 040 22
- Recruiting
- CARDIO D&R, s.r.o.
-
Nitra, Slovakia, 949 01
- Recruiting
- Intradia s.r.o.
-
Trnava, Slovakia, 917 02
- Recruiting
- Fakultna nemocnica Trnava
-
Zilina, Slovakia, 010 01
- Recruiting
- MEDIVASA, s.r.o., Kardiologicka ambulancia 1, 2
-
-
Banskobystricky Kraj
-
Brezno, Banskobystricky Kraj, Slovakia, 977 01
- Recruiting
- Nemocnica S Poliklinikou Brezno N.O.
-
-
Presovsky Kraj
-
Svidnik, Presovsky Kraj, Slovakia, 089 01
- Recruiting
- Interna SK s.r.o.
-
-
-
-
-
Celje, Slovenia, SI-3000
- Not yet recruiting
- General hospital Celje - cardiology
-
Ljubljana, Slovenia, SI-1000
- Recruiting
- UKC Ljubljana, Cardiology department
-
Maribor, Slovenia, SI-2000
- Recruiting
- UKC Maribor - cardiology
-
-
-
-
Eastern Cape
-
George, Eastern Cape, South Africa, 6529
- Not yet recruiting
- Excellentis Clinical Trial Consultants
-
-
Free State
-
Bloemfontein, Free State, South Africa, 9301
- Recruiting
- Iatros International
-
Bloemfontein, Free State, South Africa, 9301
- Not yet recruiting
- Cardiology Research_Bloemfontein
-
-
Gauteng
-
Centurion, Gauteng, South Africa, 0157
- Recruiting
- Johese Clinical Research
-
Johannesburg, Gauteng, South Africa, 2193
- Recruiting
- Wits Clinical Research
-
Johannesburg, Gauteng, South Africa, 2013
- Recruiting
- Wits Bara Clinical Trial Site
-
Johannesburg, Gauteng, South Africa, 2192
- Recruiting
- Dr Garda Cardiology Practice
-
Lenasia, Gauteng, South Africa, 1827
- Recruiting
- Lenasia Clinical Trial Centre
-
Pretoria, Gauteng, South Africa, 0157
- Recruiting
- Raslouw Private Hospital
-
Pretoria, Gauteng, South Africa, 0002
- Recruiting
- RYEXO Clinical Research
-
Pretoria, Gauteng, South Africa, 0002
- Not yet recruiting
- RYEXO Clinical Research
-
Pretoria, Gauteng, South Africa, 0083
- Withdrawn
- Dr Mpe's Practice
-
Pretoria, Gauteng, South Africa, 0184
- Recruiting
- Synexus Watermeyer Clinical Research Centre
-
-
KwwaZulu Natal
-
Durban, KwwaZulu Natal, South Africa, 4300
- Not yet recruiting
- KwaPhila Health Solutions
-
-
Western Cape
-
Cape Town, Western Cape, South Africa, 7130
- Recruiting
- Synexus Helderberg Clinical Research Centre
-
Cape Town, Western Cape, South Africa, 7130
- Not yet recruiting
- Synexus Helderberg Clinical Research Centre
-
Cape Town, Western Cape, South Africa, 7500
- Recruiting
- Dr Corbett
-
Cape Town, Western Cape, South Africa, 7500
- Active, not recruiting
- Tread Research (Pty)Ltd
-
Cape Town, Western Cape, South Africa, 7530
- Not yet recruiting
- Tiervlei Trial Centre
-
Cape Town, Western Cape, South Africa, 7935
- Recruiting
- Cardiac Clinical Research Unit, University of Cape Town
-
Mossel Bay, Western Cape, South Africa, 6506
- Recruiting
- Dr Hendrik Snyman's Practice
-
Worcester, Western Cape, South Africa, 6850
- Not yet recruiting
- Clinical Projects Research
-
Worcester, Western Cape, South Africa, 6850
- Recruiting
- Clinical Projects Research
-
-
-
-
-
Las Palmas de Gran Canaria, Spain, 35010
- Recruiting
- Hospital Universitario de Gran Canaria Doctor Negrín
-
Madrid, Spain, 28040
- Recruiting
- Hospital Clinico San Carlos
-
Madrid, Spain, 28034
- Recruiting
- Hospital Ramón y Cajal
-
Madrid, Spain, 28222
- Recruiting
- Hospital Universitario Puerta de Hierro Majadahonda
-
Sevilla, Spain, 41003
- Recruiting
- Clínica Nuevas Tecnologías en Diabetes y Endocrinología
-
-
Barcelona
-
Badalona, Barcelona, Spain, 08916
- Recruiting
- Hospital Germans Trias i Pujol
-
L'Hospitalet de Llobregat, Barcelona, Spain, 08907
- Recruiting
- Hospital de Bellvitge
-
-
-
-
-
Kaohsiung city, Taiwan, 807
- Recruiting
- Kaohsiung Medical University Chung-Ho Memorial Hospital
-
Taichung City, Taiwan, 407
- Recruiting
- Taichung Veterans General Hospital
-
Taipei, Taiwan, 112
- Recruiting
- Taipei Veterans General Hospital
-
Taipei, Taiwan, 112
- Withdrawn
- Taipei Veterans General Hospital
-
Taipei city, Taiwan, 110
- Recruiting
- Taipei Medical University Hospital
-
Taoyuan city, Taiwan, 333
- Recruiting
- Chang Gung Medical Foundation - Linkou Branch
-
-
-
-
-
Bangkok, Thailand, 10700
- Recruiting
- Siriraj Hospital
-
Bangkok, Thailand, 10330
- Recruiting
- King Chulalongkorn Memorial Hospital
-
Bangkok, Thailand, 10330
- Not yet recruiting
- King Chulalongkorn Memorial Hospital
-
Bangkok, Thailand, 10210
- Not yet recruiting
- Chulabhorn Hospital
-
Bangkok, Thailand, 10300
- Not yet recruiting
- Cardio-Vajira
-
Bangkok, Thailand, 10300
- Recruiting
- Cardio-Vajira
-
Bangkok, Thailand, 10400
- Recruiting
- Ramathibodi Hospital-Cardiovascular metabolic Center
-
Chiang Mai, Thailand, 50200
- Recruiting
- Maharaj Nakorn Chiang Mai Hospital
-
Khon Kaen, Thailand, 40002
- Recruiting
- Srinagarind Hospital
-
Ubon Ratchathani, Thailand, 34000
- Recruiting
- Sunpasitthiprasong Hospital
-
-
Pathumthani
-
Klong Luang, Pathumthani, Pathumthani, Thailand, 12120
- Recruiting
- Thammasat University Hospital
-
-
Songkla
-
Hat Yai, Songkla, Thailand, 90110
- Recruiting
- Songklanagarind hospital
-
-
-
-
-
Afyon, Turkey, 03200
- Recruiting
- Afyonkarahisar Health Sciences University
-
Afyon, Turkey, 03200
- Not yet recruiting
- Afyonkarahisar Health Sciences University
-
Ankara, Turkey, 06230
- Recruiting
- Hacettepe University Medical Faculty_Ankara
-
Antalya, Turkey, 07059
- Recruiting
- Akdeniz University Medical Faculty
-
Antalya, Turkey, 07059
- Not yet recruiting
- Akdeniz University Medical Faculty
-
Edirne, Turkey, 22030
- Recruiting
- Trakya University
-
Eskisehir, Turkey, 26040
- Recruiting
- Eskisehir Osmangazi University-Cardio
-
Istanbul, Turkey, 34303
- Not yet recruiting
- Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training Research Hospital_Istanbul
-
Istanbul, Turkey, 34668
- Not yet recruiting
- Dr. Siyami Ersek Gogus Kalp ve Damar Cerrahisi EAH
-
Izmir, Turkey, 35100
- Not yet recruiting
- Ege University School of Medicine, Cardiology Department
-
Izmir, Turkey, 35340
- Not yet recruiting
- Dokuz Eylul University School of Medicine, Cardiology
-
Kayseri, Turkey, 38039
- Recruiting
- Erciyes University Cardiology
-
Kocaeli, Turkey, 41380
- Not yet recruiting
- Kocaeli Universitesi Tip Fakultesi Hastanesi
-
Mersin, Turkey, 33343
- Not yet recruiting
- Mersin University Cardiology
-
-
-
-
-
Aberdeen, United Kingdom, AB25 2ZN
- Recruiting
- Aberdeen Royal Infirmary
-
Bristol, United Kingdom, BS10 5NB
- Recruiting
- Southmead Hospital
-
Bristol, United Kingdom, BS10 5NB
- Not yet recruiting
- Southmead Hospital
-
Craigavon, United Kingdom, BT63 5QQ
- Recruiting
- Craigavon Area Hospital
-
Dorest, United Kingdom, BH7 7DW
- Not yet recruiting
- Royal Bournemouth Hospital
-
Dorset, United Kingdom, BH7 7DW
- Recruiting
- Royal Bournemouth Hospital
-
Exeter, United Kingdom, EX2 5DW
- Recruiting
- Royal Devon University Healthcare NHS Foundation Trust
-
Exeter, United Kingdom, EX2 5DW
- Not yet recruiting
- Royal Devon University Healthcare NHS Foundation Trust
-
Glasgow, United Kingdom, G31 2ER
- Recruiting
- Glasgow Clinical Research Facility
-
High Wycombe, United Kingdom, HP11 2TT
- Recruiting
- Wycombe General Hospital
-
Liverpool, United Kingdom, L9 7AL
- Recruiting
- University Hospital Aintree
-
Manchester, United Kingdom, M13 9WL
- Recruiting
- Manchester Royal Infirmary_Manchester_0
-
North Shields, United Kingdom, NE29 8NH
- Recruiting
- North Tyneside General Hospital
-
Oxford, United Kingdom, OX3 9DU
- Not yet recruiting
- John Radcliffe Hospital
-
Oxford, United Kingdom, OX3 9DU
- Recruiting
- John Radcliffe Hospital
-
Stockton-on-Tees, United Kingdom, TS19 8PE
- Recruiting
- University of North Tees Hospital
-
Stockton-on-Tees, United Kingdom, TS19 8PE
- Not yet recruiting
- University of North Tees Hospital
-
-
Essex
-
Basildon, Essex, United Kingdom, SS16 5NL
- Recruiting
- Basildon University Hospital
-
Basildon, Essex, United Kingdom, SS16 5NL
- Not yet recruiting
- Basildon University Hospital
-
-
Lanarkshire
-
Airdrie, Lanarkshire, United Kingdom, ML6 0JS
- Recruiting
- University Hospital Monklands
-
-
London
-
Tooting, London, United Kingdom, SW17 0RE
- Recruiting
- St George's Hospital
-
Tooting, London, United Kingdom, SW17 0RE
- Not yet recruiting
- St George's Hospital
-
-
South Lanarkshire
-
East Kilbride, South Lanarkshire, United Kingdom, G74 8RG
- Recruiting
- University Hospital Hairmyres
-
-
West Sussex
-
Chichester, West Sussex, United Kingdom, PO19 6SE
- Recruiting
- St. Richards Hospital
-
-
-
-
Alabama
-
Alexander City, Alabama, United States, 35010
- Recruiting
- Advanced Cariodvascular LLC
-
Fairhope, Alabama, United States, 36532
- Recruiting
- Eastern Shore Rsrch Inst, LLC
-
Huntsville, Alabama, United States, 35801
- Recruiting
- Heart Center Rsrch_Hunstville
-
-
Arizona
-
Phoenix, Arizona, United States, 85006
- Not yet recruiting
- Banner University Medical Ctr
-
-
Arkansas
-
Little Rock, Arkansas, United States, 72204
- Recruiting
- Cardiology & Medicine Clinic
-
-
California
-
Beverly Hills, California, United States, 90211
- Recruiting
- National Heart Institute Cal
-
Covina, California, United States, 91723
- Recruiting
- Valley Clinical Trials
-
La Jolla, California, United States, 90237
- Not yet recruiting
- Scripps Memorial Hospital La Jolla
-
La Mesa, California, United States, 91942
- Recruiting
- Purushotham & Akther Kotha MD, inc.
-
Loma Linda, California, United States, 92357
- Recruiting
- VA Loma Linda Hlthcr Sys
-
Los Angeles, California, United States, 90073
- Recruiting
- VA Greater Los Angeles Hlthcare System
-
Northridge, California, United States, 91325
- Recruiting
- Valley Clinical Trials, Inc.
-
Orange, California, United States, 92868
- Recruiting
- UCI Health
-
Palo Alto, California, United States, 94304
- Withdrawn
- Stanford Univ School of Med
-
San Diego, California, United States, 92123
- Recruiting
- San Diego Cardiac Center
-
San Dimas, California, United States, 91773
- Recruiting
- North America Research Institute
-
Stockton, California, United States, 95204
- Recruiting
- Manshadi Heart Institute
-
Torrance, California, United States, 90502
- Recruiting
- Lundquist Inst-Biomed Innovtn
-
Van Nuys, California, United States, 91405
- Recruiting
- InvivoCure
-
-
Colorado
-
Aurora, Colorado, United States, 80045
- Recruiting
- Rocky Mountain Regional VAMC
-
Littleton, Colorado, United States, 80120
- Withdrawn
- S Denver Cardiology Associates
-
-
Connecticut
-
Bridgeport, Connecticut, United States, 06610
- Recruiting
- Bridgeport Hospital
-
Stamford, Connecticut, United States, 06905
- Recruiting
- Cardiology Associates of Fairfield County
-
-
Florida
-
Crystal River, Florida, United States, 34429
- Recruiting
- Nature Coast Clin Rsrch_Crystal River
-
Fort Lauderdale, Florida, United States, 33312
- Withdrawn
- Integrative Research Assoc Inc
-
Hollywood, Florida, United States, 33021
- Recruiting
- Memorial Region Hosp_Hollywood
-
Jacksonville, Florida, United States, 32204
- Withdrawn
- E Coast Inst for Rsrch LLC_Jacksonville
-
Jacksonville, Florida, United States, 32216
- Recruiting
- Jacksonville Ctr For Clin Res
-
Jacksonville, Florida, United States, 32258
- Recruiting
- Baptist Health Research Institute
-
Miami, Florida, United States, 33133
- Recruiting
- Pioneer Clinical Studies
-
Miami, Florida, United States, 33173
- Not yet recruiting
- Baptist Health South Florida
-
Miami, Florida, United States, 33137
- Recruiting
- Amavita Research Services, LLC
-
Naples, Florida, United States, 34102
- Recruiting
- NCH Research Institute
-
Ocala, Florida, United States, 34471
- Recruiting
- Ocala Cardiovascular Research
-
Saint Augustine, Florida, United States, 32086
- Recruiting
- St Johns Ctr Clin Rsch-St. Aug
-
Wellington, Florida, United States, 33449
- Recruiting
- Cardio Partners Clin Res Inst
-
Winter Haven, Florida, United States, 33881
- Recruiting
- Winter Haven Hospital
-
-
Georgia
-
Atlanta, Georgia, United States, 30310
- Recruiting
- Morehouse School Of Medicine
-
Atlanta, Georgia, United States, 30322
- Not yet recruiting
- Emory University School of Medicine_Atlanta
-
Johns Creek, Georgia, United States, 30024
- Recruiting
- NSC Research, Inc
-
Macon, Georgia, United States, 31201
- Recruiting
- GA Arrhythmia Cons & Rsch Inst
-
-
Hawaii
-
Honolulu, Hawaii, United States, 96817
- Withdrawn
- The Queen's Medical Center
-
-
Idaho
-
Meridian, Idaho, United States, 83642
- Recruiting
- St. Luke's Idaho Cardiology Associates
-
-
Illinois
-
Arlington Heights, Illinois, United States, 60005
- Recruiting
- Northwest Heart Clinical Research, LLC
-
Downers Grove, Illinois, United States, 60515
- Recruiting
- Advocate Good Samaritan
-
Hazel Crest, Illinois, United States, 60429
- Recruiting
- Chicago Medical Research LLC
-
Naperville, Illinois, United States, 60540
- Recruiting
- CIS Research _Naperville
-
Peoria, Illinois, United States, 61614
- Recruiting
- OSF HealthCare_Cardiovasc Inst
-
Peoria, Illinois, United States, 61636
- Recruiting
- Methodist Medical_Center of Illinois
-
-
Indiana
-
Elkhart, Indiana, United States, 46514
- Recruiting
- Midwest Cardiovascu Rsrch Foundation
-
Hammond, Indiana, United States, 46324
- Recruiting
- Asha Clinical Rsch-Munster, LLC
-
Indianapolis, Indiana, United States, 46237
- Recruiting
- Franciscan Network-IN Heart PHY
-
Lebanon, Indiana, United States, 46052
- Withdrawn
- Witham Health Services
-
Munster, Indiana, United States, 46321
- Recruiting
- Cardiovascular Rsrch of NW_IN
-
Richmond, Indiana, United States, 47374
- Recruiting
- Reid Physician Associates
-
-
Iowa
-
Iowa City, Iowa, United States, 52242
- Not yet recruiting
- University of Iowa Hospitals and Clinics
-
-
Kansas
-
Overland Park, Kansas, United States, 66211
- Recruiting
- Midwest Heart & Vasc Spec
-
Overland Park, Kansas, United States, 66211
- Not yet recruiting
- Midwest Heart & Vasc Spec
-
-
Kentucky
-
Elizabethtown, Kentucky, United States, 42701
- Recruiting
- Baptist Health_Elizabethtown
-
Lexington, Kentucky, United States, 40503
- Recruiting
- The Research Group of Lexington LLC
-
Louisville, Kentucky, United States, 40202
- Recruiting
- University of Louisville
-
Louisville, Kentucky, United States, 40207
- Recruiting
- Baptist Health Louisville
-
Louisville, Kentucky, United States, 40206
- Withdrawn
- Robley Rex VA Medical Center
-
-
Louisiana
-
Alexandria, Louisiana, United States, 71301
- Recruiting
- Cambridge Medical Trials
-
Bogalusa, Louisiana, United States, 70427
- Recruiting
- Louisiana Heart Center
-
Hammond, Louisiana, United States, 70403
- Recruiting
- Heart Clinic of Hammond
-
New Orleans, Louisiana, United States, 70112
- Recruiting
- University Medical Center New Orleans
-
-
Maryland
-
Baltimore, Maryland, United States, 21229
- Recruiting
- Ascension Saint Agnes Heart Ca
-
Baltimore, Maryland, United States, 21287
- Not yet recruiting
- Johns Hopkins University_Baltimore
-
Lanham, Maryland, United States, 20706
- Recruiting
- Capitol Cardiology Assoc_Lanham
-
Oxon Hill, Maryland, United States, 20745
- Recruiting
- MD Medical Research
-
-
Massachusetts
-
Haverhill, Massachusetts, United States, 01830
- Recruiting
- Pentucket Medical Associates
-
-
Michigan
-
Ann Arbor, Michigan, United States, 48109
- Recruiting
- University of Michigan Medicine
-
Detroit, Michigan, United States, 48201
- Not yet recruiting
- Detroit Med Center-Wayne State
-
Detroit, Michigan, United States, 48202
- Recruiting
- Henry Ford Hlth System_Detroit
-
Flint, Michigan, United States, 48532
- Recruiting
- Elite Research Center
-
Grand Rapids, Michigan, United States, 49546
- Recruiting
- Healthy Heart Cardiology
-
Ypsilanti, Michigan, United States, 48197
- Recruiting
- Trinity Health Michigan Heart
-
-
Minnesota
-
Maplewood, Minnesota, United States, 55109
- Recruiting
- Fairview Health Services
-
Maplewood, Minnesota, United States, 55109
- Not yet recruiting
- Fairview Health Services
-
Minneapolis, Minnesota, United States, 55417
- Recruiting
- Minneapolis VA Health Care Sys
-
-
Mississippi
-
Tupelo, Mississippi, United States, 38801
- Recruiting
- Cardiolg Assoc Rsch LLC_Tupelo
-
-
Missouri
-
Saint Louis, Missouri, United States, 63136
- Recruiting
- St Louis Heart & Vascular, P.C.
-
-
Montana
-
Kalispell, Montana, United States, 59901
- Recruiting
- Logan Health Research
-
-
Nebraska
-
Omaha, Nebraska, United States, 68198
- Recruiting
- Univ. of Nebraska Medical Center_Omaha
-
-
New Jersey
-
Bridgewater, New Jersey, United States, 08807-3064
- Withdrawn
- Advanced Heart Care LLC
-
Elmer, New Jersey, United States, 08318
- Recruiting
- Heart House_Elmer
-
Linden, New Jersey, United States, 07036
- Not yet recruiting
- NJ Heart
-
Linden, New Jersey, United States, 07036
- Recruiting
- NJ Heart
-
Livingston, New Jersey, United States, 07039
- Not yet recruiting
- Barnabas Health
-
Mullica Hill, New Jersey, United States, 08062
- Recruiting
- Inspira Health
-
Newark, New Jersey, United States, 07102
- Recruiting
- Saint Michael's Med Ctr NJ
-
Newark, New Jersey, United States, 07102
- Not yet recruiting
- Saint Michael's Med Ctr NJ
-
Ridgewood, New Jersey, United States, 07450
- Withdrawn
- The Valley Hosptial
-
Ridgewood, New Jersey, United States, 07450
- Not yet recruiting
- The Valley Hosptial
-
-
New York
-
Albany, New York, United States, 12211
- Recruiting
- Capital Cardiology Associates_Albany
-
Bronx, New York, United States, 10455
- Recruiting
- Chear Center LLC
-
Buffalo, New York, United States, 14215
- Withdrawn
- University at Buffalo_Erie County Med Ctr
-
Kew Gardens, New York, United States, 11415
- Recruiting
- Marian David, MD, PC
-
New York, New York, United States, 10021
- Recruiting
- NY Presbyt Hosp-W Cornell Med
-
New York, New York, United States, 10035
- Recruiting
- Harlem Cardiology_Madison ave
-
New York, New York, United States, 10019
- Recruiting
- Mount Sinai Hosp at NYC
-
New York, New York, United States, 10029
- Recruiting
- Mount Sinai Hosp at NYC
-
Rosedale, New York, United States, 11422
- Recruiting
- Laurelton Heart Specialist PC
-
Rosedale, New York, United States, 11422
- Not yet recruiting
- Laurelton Heart Specialist PC
-
Saratoga Springs, New York, United States, 12866
- Recruiting
- Saratoga Clinical Research
-
Stony Brook, New York, United States, 11794
- Recruiting
- Stony Brook University Hospital
-
-
North Carolina
-
Chapel Hill, North Carolina, United States, 27599
- Recruiting
- UNC Cardiology Outpatient Ctr
-
Durham, North Carolina, United States, 27710
- Recruiting
- Duke University
-
Greensboro, North Carolina, United States, 27405
- Recruiting
- Medication Mgmnt, LLC_Grnsboro
-
Lumberton, North Carolina, United States, 28358
- Not yet recruiting
- Duke University/Southeastern
-
Lumberton, North Carolina, United States, 28358
- Recruiting
- Duke University/Southeastern
-
Morehead City, North Carolina, United States, 28557
- Recruiting
- Carteret Medical Group
-
Raleigh, North Carolina, United States, 27607
- Recruiting
- UNC Rex Healthcare
-
-
Ohio
-
Canton, Ohio, United States, 44710
- Recruiting
- Aultman Hospital
-
Marion, Ohio, United States, 43302
- Recruiting
- Rama Research LLC
-
-
Oklahoma
-
Oklahoma City, Oklahoma, United States, 73135
- Recruiting
- South Oklahoma Heart Research, LLC
-
-
Pennsylvania
-
Camp Hill, Pennsylvania, United States, 17011
- Recruiting
- Capital Area Cardio Assoc
-
Camp Hill, Pennsylvania, United States, 17011
- Recruiting
- Penn State Hlth Holy Spirit Med Ctr
-
Danville, Pennsylvania, United States, 17822
- Not yet recruiting
- Geisinger Medical Center
-
Hershey, Pennsylvania, United States, 17033
- Not yet recruiting
- Penn State Hershey Medical Center
-
Lancaster, Pennsylvania, United States, 17603
- Recruiting
- Heart Grp_ Lancaster Gen Hlth
-
Philadelphia, Pennsylvania, United States, 19114
- Recruiting
- Thomas Jefferson University_Philadelphia
-
Pittsburgh, Pennsylvania, United States, 15212
- Withdrawn
- Allegheny Health Network
-
Wyomissing, Pennsylvania, United States, 19610
- Recruiting
- Penn State Health-Berks Cardiology
-
-
South Carolina
-
Columbia, South Carolina, United States, 29203
- Withdrawn
- Prisma Health-Midlands
-
-
South Dakota
-
Rapid City, South Dakota, United States, 57701
- Recruiting
- Monument Health Clinical Rsrch
-
Sioux Falls, South Dakota, United States, 57117
- Not yet recruiting
- Sanford Health_Sioux Falls
-
-
Tennessee
-
Jackson, Tennessee, United States, 38305
- Recruiting
- The Jackson Clinic, PA
-
Jackson, Tennessee, United States, 38301
- Recruiting
- Apex Research Foundation, LLC
-
Knoxville, Tennessee, United States, 37934
- Recruiting
- Tennova Healthcare-Turkey Creek Medical Center
-
-
Texas
-
Allen, Texas, United States, 75013
- Recruiting
- Heart MD_Allen TX
-
Amarillo, Texas, United States, 79109
- Recruiting
- PharmaTex Research, LLC
-
Austin, Texas, United States, 78756
- Not yet recruiting
- Austin Heart
-
Dallas, Texas, United States, 75390
- Recruiting
- UTD SW Medical Center-Dallas
-
Duncanville, Texas, United States, 75137
- Recruiting
- Dallas Heart and Vascular
-
El Paso, Texas, United States, 79905
- Recruiting
- David Turbay, MD, PLLC
-
Houston, Texas, United States, 77030
- Not yet recruiting
- Houston Methodist Hospital
-
Houston, Texas, United States, 77025
- Recruiting
- Biopharma Informatic_Houston
-
Houston, Texas, United States, 77030
- Recruiting
- Texas Heart Inst Medical Ctr
-
Houston, Texas, United States, 77030
- Not yet recruiting
- UT Physicians - Houston Medical Center
-
Houston, Texas, United States, 77070
- Recruiting
- Cardiovasc Spec of Willowbrook
-
McKinney, Texas, United States, 75071
- Recruiting
- Texas Institute of Cardiology PA
-
San Antonio, Texas, United States, 78229
- Recruiting
- Audie L. Murphy VA Hospital
-
San Antonio, Texas, United States, 78212
- Recruiting
- Clinical Advancement Ctr, PLLC
-
Sherman, Texas, United States, 75092
- Recruiting
- Sherman Clinical Research
-
-
Vermont
-
Burlington, Vermont, United States, 05401
- Recruiting
- University of Vermont Medical Center
-
-
Virginia
-
Charlottesville, Virginia, United States, 22908
- Recruiting
- University of Virginia
-
Chesterfield, Virginia, United States, 23832
- Recruiting
- James River Cardiology
-
Falls Church, Virginia, United States, 22042
- Withdrawn
- Virginia Heart
-
Manassas, Virginia, United States, 20109
- Recruiting
- Carient Heart and Vascular
-
Norfolk, Virginia, United States, 23504
- Not yet recruiting
- York Clinical Research LLC
-
Norfolk, Virginia, United States, 23507
- Recruiting
- Sentara Clinical Research
-
Richmond, Virginia, United States, 23298
- Withdrawn
- Virginia Commonwealth University
-
Roanoke, Virginia, United States, 24014
- Recruiting
- Roanoke Heart Institute
-
Salem, Virginia, United States, 24153-6404
- Recruiting
- VA Medical Center_Salem
-
Winchester, Virginia, United States, 22601-3834
- Recruiting
- Selma Medical Associates
-
Winchester, Virginia, United States, 22601
- Not yet recruiting
- Valley Health Link
-
-
Washington
-
Seattle, Washington, United States, 98101
- Not yet recruiting
- Virginia Mason Medical Center
-
Seattle, Washington, United States, 98122-5789
- Not yet recruiting
- Swedish Medical Center_Seattle
-
Spokane, Washington, United States, 99204
- Recruiting
- Providence Med Research Ctr
-
-
West Virginia
-
Morgantown, West Virginia, United States, 26506
- Withdrawn
- WVU Heart & Vascular Institute
-
-
Wisconsin
-
Madison, Wisconsin, United States, 53705
- Not yet recruiting
- William S Middleton Mem VA Hosp
-
Milwaukee, Wisconsin, United States, 53215
- Recruiting
- Aurora St. Luke's Medical Centr
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
- Serum high-sensitivity C-reactive protein (hs-CRP) greater than equal to 2 milligrams per liter (mg/L) at screening (visit 1) Disease specific - cardiovascular
At least one of the following:
- N-terminal-pro-brain natriuretic peptide (NT-proBNP) greater than equal to 300 picograms per milliliter (pg/mL) at screening (Visit 1) for patients without ongoing atrial fibrillation/flutter. If ongoing atrial fibrillation/flutter at screening (visit 1), NTproBNP must be greater than equal to 600 pg/mL. Note that the screening electrocardiogram (ECG) must be obtained the same day as sampling for NT-proBNP.
- Hospitalisation or urgent/unplanned visit with a primary diagnosis of decompensated heart failure which required intravenous loop diuretic treatment, within the last 9 months prior to screening (visit 1) in combination with NT-proBNP greater than equal to 200 pg/mL at screening (Visit 1) for patients without ongoing atrial fibrillation/flutter. If ongoing atrial fibrillation/flutter at screening (visit 1), NT-proBNP must be greater than equal to 600 pg/mL.
- Diagnosis of heart failure (New York Heart Association [classification] [NYHA] Class II-IV).
- Left ventricular ejection fraction (LVEF) greater than 40 percentage (%) documented by echocardiography within 12 months prior to or at screening (visit 1). The LVEF must be documented in medical records and the most recent measurement must be used to determine eligibility with no interim event signalling potential deterioration in ejection fraction (e.g., myocardial infarction [MI] or heart failure [HF] hospitalisation).
- Structural heart disease and/or functional heart disease documented by echocardiography within 12 months prior to or at screening (visit 1) showing at least one of the following:
- Left atrial (LA) volume index greater than 34 milliliter per meter square (mL/m^2).
- LA diameter greater than equal to 3.8 centimeter (cm).
- LA length greater than equal to 5.0 cm.
- LA area greater than equal to 20 cm square.
- LA volume greater than equal to 55 milliters (mL).
- Intraventricular septal thickness greater than equal to 1.1 cm.
- Posterior wall thickness greater than equal to 1.1 cm.
- Left ventricular (LV) mass index greater than equal to 115 grams per meter square (g⁄m^2 ) in men or greater than equal to 95 g⁄m^2 in women.
- E/e' (mean septal and lateral) greater than equal to 10.
- e' (mean septal and lateral) less than 9 centimeter per second (cm/s).
- No heart failure hospitalisations or urgent heart failure visits between screening (visit 1) and randomisation (visit 2).
Exclusion Criteria:
Medical conditions - cardiovascular
- Myocardial infarction, stroke, unstable angina pectoris, transient ischaemic attack, or heart failure hospitalisation, within 30 days prior to screening (visit 1).
- Systolic blood pressure greater than equal to 180 millimeters of mercury (mmHg) at screening (visit 1). If the systolic blood pressure is 160-179 mmHg, the patient should be receiving greater than equal to 3 antihypertensive drugs. (Note: Potential participants may be retested for this criterion within the visit window and without rescreening, at the discretion of the investigator).
- Heart rate above 110 or below 40 beats per minute as evaluated on the electrocardiogram (ECG) performed at screening (visit 1) (Note: Potential participants may be retested for this criterion within the visit window and without rescreening, at the discretion of the investigator).
- Planned coronary, carotid or peripheral artery revascularisation known during the screening period (visit 1). (Note: Planned coronary angiogram is not exclusionary).
- Planned cardiac device or atrial flutter/atrial fibrillation ablation procedure known during the screening period (visit 1).
- Major cardiac surgical, non-cardiac surgical, or major endoscopic procedure (thoracoscopic or laparoscopic) within the past 60 days prior to randomisation (visit 2) or any major surgical procedure planned at the time of randomisation (visit 2).
- Heart failure due to infiltrative cardiomyopathy (e.g., sarcoid, amyloid), arrhythmogenic right ventricular cardiomyopathy, Takutsubo cardiomyopathy, genetic hypertrophic cardiomyopathy or obstructive cardiomyopathy, active myocarditis, constrictive pericarditis, cardiac tamponade, uncorrected more than moderate primary valve disease.
- Primary pulmonary hypertension, chronic pulmonary embolism, severe pulmonary disease including COPD.
- Any other condition judged by the investigator that could account for heart failure symptoms and signs (e.g., anaemia, hypothyroidism).
Medical conditions - infections/immunosuppression
- Clinical evidence of, or suspicion of, active infection at the discretion of the investigator.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Quadruple
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Ziltivekimab 15 mg
Participants will receive ziltivekimab 15 milligrams (mg) subcutaneous (s.c.) injection once-monthly and added standard of care for up to 4 years.
|
Ziltivekimab 15 milligrams (mg) subcutaneous (s.c.) injection in a pre-filled syringe or a pen-injector once-monthly for up to 4 years.
|
|
Placebo Comparator: Placebo
Participants will receive ziltivekimab placebo s.c.
injection once-monthly and added standard of care for up to 4 years.
|
Ziltivekimab placebo s.c.
injection in a pre-filled syringe or a pen-injector once-monthly for up to 4 years.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Time to First Occurrence of a Composite Heart Failure Endpoint Consisting of: Cardiovascular (CV) Death, Heart Failure (HF) Hospitalisation or Urgent HF Visit
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Measured in months.
|
From randomisation (month 0) to end of study (up to 48 months)
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Number of CV Deaths, HF Hospitalisations or Urgent HF Visits (First and Recurrent)
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Measured as count of event.
|
From randomisation (month 0) to end of study (up to 48 months)
|
|
Time to First Occurrence of 4-point Expanded Composite HF Endpoint, a Composite Endpoint Consisting of: CV Death, HF Hospitalisation or Urgent HF Visit, Non-fatal Myocardial Infarction (MI), Non-fatal Stroke
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Measured in months.
|
From randomisation (month 0) to end of study (up to 48 months)
|
|
Time to First Occurrence of 4-point Expanded Composite HF Endpoint, a Composite Endpoint Consisting of: All-cause Death, HF Hospitalisation or Urgent HF Visit, Non-fatal MI, Non-fatal stroke
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Measured in months.
|
From randomisation (month 0) to end of study (up to 48 months)
|
|
Time to Occurrence of CV Death
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Measured in months.
|
From randomisation (month 0) to end of study (up to 48 months)
|
|
Time to First Occurrence of HF Hospitalisation or Urgent HF Visit
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Measured in months.
|
From randomisation (month 0) to end of study (up to 48 months)
|
|
Number of Events of Atrial Fibrillation
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Measured as count of event.
|
From randomisation (month 0) to end of study (up to 48 months)
|
|
Change in KCCQ Clinical Summary Score
Time Frame: From randomisation (month 0) to 12 months
|
KCCQ measures Health-Related Quality of Life (HRQOL) and is a disease-specific health status instrument for HF.
Score ranges from 0 to 100, with 0 as the lowest score and 100 as the highest score.
Higher scores indicate better health status, fewer symptoms, and greater disease-specific health related quality of life, respectively.
Measured as score.
|
From randomisation (month 0) to 12 months
|
|
Improvement of 5 Points or More in KCCQ Clinical Summary Score (Yes/No)
Time Frame: From randomisation (month 0) to 12 months
|
Kansas City Cardiomyopathy Questionnaire (KCCQ) measures Health-Related Quality of Life (HRQOL) and is a disease-specific health status instrument for HF.
Score ranges from 0 to 100, with 0 as the lowest score and 100 as the highest score.
Higher scores indicate better health status, fewer symptoms, and greater disease-specific health related quality of life, respectively.
Measured as count of participant.
|
From randomisation (month 0) to 12 months
|
|
Improvement of 10 Points or More in KCCQ Clinical Summary Score (Yes/No)
Time Frame: From randomisation (month 0) to 12 months
|
Kansas City Cardiomyopathy Questionnaire (KCCQ) measures Health-Related Quality of Life (HRQOL) and is a disease-specific health status instrument for HF.
Score ranges from 0 to 100, with 0 as the lowest score and 100 as the highest score.
Higher scores indicate better health status, fewer symptoms, and greater disease-specific health related quality of life, respectively.
Measured as count of participant.
|
From randomisation (month 0) to 12 months
|
|
Improvement in New York Heart Association (Classification) [NYHA Class] (Yes/No)
Time Frame: From randomisation (month 0) to 12 months
|
NEW YORK HEART ASSOCIATION CLASSIFICATION (NYHA) Class I: Participant with cardiac disease but without resulting limitations of physical activity. Class II: Participants with cardiac disease resulting in slight limitation of physical activity. Class III: Participants with cardiac disease resulting in marked limitation of physical activity. Class IV: Participants with cardiac disease resulting in inability to carry on any physical activity without discomfort. Measured as count of participant. |
From randomisation (month 0) to 12 months
|
|
Change in Estimated Glomerular Filtration Rate (eGFR) (Chronic Kidney Disease - Epidemiology Collaboration [CKD-EPI])
Time Frame: From randomisation (month 0) to 12 months
|
Measured as mL/min/1.73 m^2.
|
From randomisation (month 0) to 12 months
|
|
Annual Rate of Change in eGFR (CKD-EPI) (Total eGFR Slope)
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Measured as mL/min/1.73
m^2/year.
|
From randomisation (month 0) to end of study (up to 48 months)
|
|
Number of Hospitalisations With Infection as Primary Cause or Death Due to Infection
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Measured as count of event.
|
From randomisation (month 0) to end of study (up to 48 months)
|
|
Change in High-sensitivity C-reactive Protein (hs-CRP)
Time Frame: From randomisation (month 0) to 12 months
|
Measured as ratio to baseline.
|
From randomisation (month 0) to 12 months
|
|
Change in N-terminal-pro-brain Natriuretic Peptide (NT-proBNP)
Time Frame: From randomisation (month 0) to 12 months
|
Measured as ratio to baseline.
|
From randomisation (month 0) to 12 months
|
|
Time to Occurrence of all-cause Death
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Measured in months.
|
From randomisation (month 0) to end of study (up to 48 months)
|
|
Hierarchical Composite of: Time to All-cause Death, Number of HF Hospitalisations or Urgent HF Visits, Time to First HF Hospitalisation or Urgent HF Visit, difference of at least 5 in KCCQ clinical summary score change from baseline to 12 months
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
Kansas City Cardiomyopathy Questionnaire (KCCQ) measures Health-Related Quality of Life (HRQOL) and is a disease-specific health status instrument for HF.
Score ranges from 0 to 100, with 0 as the lowest score and 100 as the highest score.
Higher scores indicate better health status, fewer symptoms, and greater disease-specific health related quality of life, respectively.
Measured as total wins for each treatment group.
|
From randomisation (month 0) to end of study (up to 48 months)
|
|
Time to First Occurrence of a Composite Chronic Kidney Disease (CKD) Endpoint Consisting of: CV death, Onset of Persistent Greater Than Equal To 40 Percentage Reduction in eGFR (CKD- EPI) compared with baseline; Kidney failure
Time Frame: From randomisation (month 0) to end of study (up to 48 months)
|
eGFR = estimated glomerular filtration rate; CKD-EPI = chronic kidney disease - epidemiology collaboration.
Kidney failure defined as: death from kidney failure, onset of persistent eGFR less than 15 milliliters per minute (mL/min)/1.73 meter square (m^2) (CKD-EPI), initiation of chronic kidney replacement therapy (maintenance dialysis or kidney transplantation).
Measured in months.
|
From randomisation (month 0) to end of study (up to 48 months)
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Study Director: Clinical Transparency (dept. 2834), Novo Nordisk A/S
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
May 8, 2023
Primary Completion (Estimated)
July 2, 2027
Study Completion (Estimated)
July 2, 2027
Study Registration Dates
First Submitted
November 23, 2022
First Submitted That Met QC Criteria
November 23, 2022
First Posted (Actual)
December 5, 2022
Study Record Updates
Last Update Posted (Actual)
April 2, 2024
Last Update Submitted That Met QC Criteria
March 31, 2024
Last Verified
March 1, 2024
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- EX6018-4915
- U1111-1280-0810 (Other Identifier: World Health Organization (WHO))
- jRCT2031230085 (Registry Identifier: jRCT (Japan))
- 2022-501939-16-00 (Other Identifier: European Medicines Agency (EMA))
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
YES
IPD Plan Description
According to the Novo Nordisk disclosure commitment on novonordisk-trials.com
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Yes
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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