A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer (SUNRAY-01)

May 18, 2026 updated by: Eli Lilly and Company

SUNRAY-01, A Global Pivotal Study in Participants With KRAS G12C-Mutant, Locally Advanced or Metastatic Non-Small Cell Lung Cancer Comparing First-Line Treatment of LY3537982 and Pembrolizumab vs Placebo and Pembrolizumab in Those With PD-L1 Expression ≥50% or LY3537982 and Pembrolizumab, Pemetrexed, Platinum vs Placebo and Pembrolizumab, Pemetrexed, Platinum Regardless of PD-L1 Expression

The purpose of this study is to assess if adding LY3537982 (olomorasib) in combination with standard of care anti-cancer drugs is more effective than standard of care in participants with untreated advanced NSCLC. NSCLC must have a change in a gene called KRAS G12C. Study participation, including follow-up, could last up to 3 years, depending on how you and your lung cancer are doing.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Dose Optimization, Part A, and Part B are randomized. Safety Lead-In for Part B is single arm, non-randomized. Part C is non-randomized.

Study Type

Interventional

Enrollment (Estimated)

1264

Phase

Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Name: Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
Phone Number: 1-317-615-4559
Email: LillyTrials@Lilly.com

Study Contact Backup

Name: Physicians interested in becoming principal investigators please contact
Email: clinical_inquiry_hub@lilly.com

Study Locations

Australia
- - Adelaide, Australia, 5000
    - Recruiting
    - Royal Adelaide Hospital
    - Principal Investigator:
      
      Harminder Takhar
  - Auchenflower, Australia, 4066
    - Recruiting
    - Icon Cancer Centre Wesley
    - Principal Investigator:
      
      Adam Stirling
  - Ballarat Central, Australia, 3350
    - Recruiting
    - Ballarat Health Services
    - Principal Investigator:
      
      Wasek Faisal
    - Contact:
      
      Phone Number: 61-03-53208500
  - Birtinya, Australia, 4575
    - Recruiting
    - Sunshine Coast University Hospital
    - Principal Investigator:
      
      Bryan Chan
    - Contact:
      
      Phone Number: 07 5202 0000
  - Gosford, Australia, 2250
    - Recruiting
    - Gosford Hospital
    - Principal Investigator:
      
      Matthew Ho Fai Wong
  - Mackay, Australia, 4740
    - Recruiting
    - Mackay Base Hospital
    - Principal Investigator:
      
      Nimisha Kumari
  - Melbourne, Australia, 3065
    - Recruiting
    - St Vincent's Hospital
    - Contact:
      
      Phone Number: 61392313155
    - Principal Investigator:
      
      Melissa Moore
  - Perth, Australia, 6009
    - Recruiting
    - Sir Charles Gairdner Hospital
    - Principal Investigator:
      
      samantha bowyer
  - Shepparton, Australia, 3630
    - Recruiting
    - Goulburn Valley Health
    - Contact:
      
      Phone Number: 61358323777
    - Principal Investigator:
      
      Myron Klevansky
  - Southport, Australia, 4215
    - Recruiting
    - Gold Coast University Hospital
    - Contact:
      
      Phone Number: 6175687000
    - Principal Investigator:
      
      Robert Mason
  - Townsville, Australia, 4814
    - Recruiting
    - The Townsville Hospital
    - Principal Investigator:
      
      Abhishek Joshi
Austria
- - Feldkirch, Austria, 6800
    - Recruiting
    - Landeskrankenhaus Feldkirch
    - Principal Investigator:
      
      Thomas Winder
    - Contact:
      
      Phone Number: 4355223032681
  - Linz, Austria, 4020
    - Recruiting
    - Ordensklinikum Linz GmbH Elisabethinen
    - Principal Investigator:
      
      Michael Schumacher
  - Vienna, Austria, 1210
    - Recruiting
    - Klinik Floridsdorf
    - Principal Investigator:
      
      Maximilian Hochmair
    - Contact:
      
      Phone Number: 43 1 27700 2212
Belgium
- - Antwerp, Belgium, 2020
    - Recruiting
    - ZNA Middelheim
    - Contact:
      
      Phone Number: 032803575
    - Principal Investigator:
      
      Kim De Muynck
  - Auderghem, Belgium, 1160
    - Recruiting
    - CHIREC - site delta
    - Principal Investigator:
      
      Christophe Compère
    - Contact:
      
      Phone Number: 0032 2 434 81 13
  - Bruges, Belgium, 8000
    - Recruiting
    - AZ Sint-Jan Brugge-Oostende AV
    - Principal Investigator:
      
      Lander Van Acker
  - Ghent, Belgium, 9000
    - Recruiting
    - UZ Gent
    - Principal Investigator:
      
      Veerle Surmont
  - Kortrijk, Belgium, 8500
    - Recruiting
    - AZ Groeninge Campus Kennedylaan
    - Contact:
      
      Phone Number: 056633340
    - Principal Investigator:
      
      Katrien Ghysen
  - Leuven, Belgium, 3000
    - Recruiting
    - UZ Leuven
    - Principal Investigator:
      
      christophe Dooms
    - Contact:
      
      Phone Number: 32 16 34 68 02
  - Mechelen, Belgium, 2800
    - Recruiting
    - AZ Sint-Maarten
    - Principal Investigator:
      
      Marc Lambrechts
    - Contact:
      
      Phone Number: +3215892040
  - Ottignies, Belgium, 1340
    - Recruiting
    - Clinique Saint Pierre
    - Principal Investigator:
      
      Luciano Carestia
    - Contact:
      
      Phone Number: 0032 10 437 298
  - Ronse, Belgium, 9600
    - Recruiting
    - AZ Glorieux Ronse
    - Principal Investigator:
      
      Patrick Alexander
    - Contact:
      
      Phone Number: 3255233668
  - Yvoir, Belgium, 5530
    - Recruiting
    - Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godinne
    - Principal Investigator:
      
      Sebahat Ocak
    - Contact:
      
      Phone Number: 081423351
Brazil
- - Barretos, Brazil, 14784400
    - Recruiting
    - Fundação Pio XII - Hospital de Câncer de Barretos
    - Principal Investigator:
      
      Carlos Baston silva
  - Bento Gonçalves, Brazil, 95700-084
    - Recruiting
    - Hospital Tacchini
    - Principal Investigator:
      
      ANDRE REIRIZ
  - Bequimão, Brazil, 65060-645
    - Recruiting
    - Hospital São Domingos
    - Principal Investigator:
      
      Antonio Alencar
  - Brasília, Brazil, 70200-730
    - Recruiting
    - Sirio-Libanes Brasilia - Centro de Oncologia - Asa Sul
    - Principal Investigator:
      
      Rafaela Ribeiro
  - Curitiba, Brazil, 80730-150
    - Recruiting
    - Hospital Universitário Evangélico Mackenzie
    - Principal Investigator:
      
      Fernanda Ronchi
    - Contact:
      
      Phone Number: +5541999744246
  - Fortaleza, Brazil, 60430235
    - Recruiting
    - Centro de Pesquisa Clínica do Instituto do Câncer do Ceará
    - Contact:
      
      Phone Number: 558532884576
    - Principal Investigator:
      
      Fabio Chaves
  - Ijuí, Brazil, 98700-000
    - Recruiting
    - ONCOSITE - Centro de Pesquisa Clinica em Oncologia
    - Contact:
      
      Phone Number: 55991592101
    - Principal Investigator:
      
      Fabio Franke
  - Lago Sul, Brazil, 71.635-610
    - Recruiting
    - Hospital Brasilia
    - Principal Investigator:
      
      Fernanda Amorim
  - Londrina, Brazil, 86015-520
    - Recruiting
    - Hospital de Cancer de Londrina
    - Contact:
      
      Phone Number: 55 41 996379769
    - Principal Investigator:
      
      Mariana Piovesana
  - Natal, Brazil, 59062-000
    - Recruiting
    - Liga Norte Riograndense Contra o Câncer
    - Principal Investigator:
      
      Sulene Oliveira
    - Contact:
      
      Phone Number: 55 84 40095595
  - Porto Alegre, Brazil, 90610-000
    - Recruiting
    - Hospital São Lucas da PUCRS
    - Principal Investigator:
      
      Ana Caroline Gelatti
  - Pouso Alegre, Brazil, 37554-216
    - Recruiting
    - Oncominas
    - Principal Investigator:
      
      Marina Zorzetto
    - Contact:
      
      Phone Number: 553534297035
  - Rio de Janeiro, Brazil, 22250-905
    - Recruiting
    - Centro de Tratamento de Tumores Botafogo para Oncoclinicas Rio de Janeiro SA
    - Principal Investigator:
      
      Tatiane Montella
  - Rio de Janeiro, Brazil, 20231-050
    - Recruiting
    - Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA
    - Contact:
      
      Phone Number: 552132076564
    - Principal Investigator:
      
      Victor Santos
  - Rio de Janeiro, Brazil, 22271-110
    - Recruiting
    - Instituto D'Or Pesquisa e Ensino
    - Principal Investigator:
      
      Clarissa Serodio da Rocha Baldotto
  - Salvador, Brazil, 41950-640
    - Recruiting
    - Clinica Amo - Rio Vermelho
    - Principal Investigator:
      
      Aknar Calabrich
    - Contact:
      
      Phone Number: 557130218735
  - Santo André, Brazil, 09060-650
    - Recruiting
    - Faculdade de Medicina do ABC
    - Principal Investigator:
      
      Claudia Vaz de Melo Sette
    - Contact:
      
      Phone Number: 551149935497
  - São José do Rio Preto, Brazil, 15090000
    - Recruiting
    - Fundação Faculdade Regional de Medicina de São José do Rio Preto
    - Principal Investigator:
      
      JOÃO SOLER
  - São José dos Campos, Brazil, 12242-660
    - Recruiting
    - COE Ensino e Pesquisa
    - Principal Investigator:
      
      Fabiano Costa
  - São Paulo, Brazil, 04014-002
    - Recruiting
    - Núcleo de Pesquisa Clínica da Rede São Camilo
    - Contact:
      
      Phone Number: 551144500360
    - Principal Investigator:
      
      Felipe José Cruz
  - São Paulo, Brazil, 04543-000
    - Recruiting
    - Instituto D'Or de Pesquisa e Ensino (IDOR)
    - Principal Investigator:
      
      Milena Perez Mak
  - São Paulo, Brazil, 01246-000
    - Recruiting
    - Icesp - Instituto Do Câncer Do Estado de São Paulo
    - Principal Investigator:
      
      Gilberto Castro
    - Contact:
      
      Phone Number: 5511999685217
  - São Paulo, Brazil, 01321-001
    - Recruiting
    - Hospital Paulistano
    - Contact:
      
      Phone Number: 11983591234
    - Principal Investigator:
      
      Cinthia Bognar
  - São Paulo, Brazil, 01452-000
    - Recruiting
    - Centro Paulista de Oncologia Clínica
    - Principal Investigator:
      
      William Nassib William Junior
    - Contact:
      
      Phone Number: 551135056616
  - São Paulo, Brazil, 04039-901
    - Recruiting
    - Instituto de Assistência Médica ao Servidor Público Estadual - IAMSPE/HSPE-FMO Conhecer Centro de Oncolog -T
    - Principal Investigator:
      
      Otavio Gampel
    - Contact:
      
      Phone Number: 1150840931
  - São Paulo, Brazil, 01321-001
    - Recruiting
    - Hospital BP
    - Principal Investigator:
      
      Marcelo Corassa
    - Contact:
      
      Phone Number: 5511985883170
  - São Paulo, Brazil, 01310-000
    - Recruiting
    - Hospital Santa Catarina - Paulista
    - Principal Investigator:
      
      Gregorio Soares
  - São Paulo, Brazil, 01308-060
    - Recruiting
    - Hospital Sirio Libanês
    - Principal Investigator:
      
      Guilherme Harada
  - Vitória, Brazil, 29055450
    - Recruiting
    - CEDOES
    - Principal Investigator:
      
      Mauricio Pereira
Canada
- - Abbotsford British Columbia, Canada, V2S 0C2
    - Recruiting
    - BC Cancer Abbotsford
    - Principal Investigator:
      
      Jasna Deluce
  - Chicoutimi, Canada, G7H 5H6
    - Recruiting
    - CIUSSS- saguenay-Lac-Saint-Jean
    - Contact:
      
      Phone Number: 4185411000
    - Principal Investigator:
      
      Jose Luiz Guimaraes
  - Vancouver, Canada, V5Z 4E6
    - Recruiting
    - BC Cancer Vancouver
    - Principal Investigator:
      
      Jamie Feng
China
- - Beijing, China, 100142
    - Recruiting
    - Beijing Cancer hospital
    - Principal Investigator:
      
      Jun Zhao
    - Contact:
      
      Phone Number: 8613521469355
  - Beijing, China, 100021
    - Recruiting
    - Cancer Hospital Chinese Academy of Medical Science
    - Principal Investigator:
      
      Ning Li
    - Contact:
      
      Phone Number: 8615601395554
  - Changchun, China, 130000
    - Recruiting
    - Jilin Province Tumor Hospital
    - Principal Investigator:
      
      Haifeng Liu
  - Changsha, China, 410013
    - Recruiting
    - Hunan Cancer Hospital
    - Principal Investigator:
      
      Lin Wu
  - Changzhou, China, 213003
    - Recruiting
    - The First People's Hospital of Changzhou
    - Principal Investigator:
      
      Mei Ji
  - Chengdu, China, 610041
    - Recruiting
    - West China Hospital, Sichuan University
    - Principal Investigator:
      
      Yan Zhang
  - Chengdu, China, 610041
    - Recruiting
    - Sichuan Cancer hospital
    - Principal Investigator:
      
      Wenxiu Yao
  - Chengdu, China, 610031
    - Recruiting
    - The Third People's Hospital of Chengdu (CDTPH)
    - Principal Investigator:
      
      yi yang
  - Fuzhou, China, 350014
    - Recruiting
    - Fujian Cancer Hospital
    - Principal Investigator:
      
      Haipeng Xu
    - Contact:
      
      Phone Number: 13675007687
  - Guangzhou, China, 510170
    - Recruiting
    - The First Affiliated Hospital of Guangzhou Medical University
    - Principal Investigator:
      
      Chengzhi Zhou
  - Haikou, China, 570311
    - Recruiting
    - Hainan General Hospital
    - Principal Investigator:
      
      yongxing chen
    - Contact:
      
      Phone Number: 13876825536
  - Hangzhou, China, 310022
    - Recruiting
    - Zhejiang Cancer Hospital
    - Principal Investigator:
      
      Zhiyu Huang
  - Hangzhou, China, 310003
    - Recruiting
    - The First Affiliated Hospital, Zhejiang University
    - Principal Investigator:
      
      Jianying Zhou
  - Hangzhou, China, 310016
    - Recruiting
    - Sir Run Run Shaw Hospital
    - Principal Investigator:
      
      Yong Fang
  - Harbin, China, 150081
    - Recruiting
    - Harbin Medical University Cancer Hospital
    - Contact:
      
      Phone Number: 13904505825
    - Principal Investigator:
      
      Yan Yu
  - Jinan, China, 250117
    - Recruiting
    - Shandong Cancer Hospital
    - Principal Investigator:
      
      Yuping Sun
  - Jinan, China, 250013
    - Recruiting
    - Jinan Central Hospital
    - Principal Investigator:
      
      Meili Sun
  - Linhai, China, 317099
    - Recruiting
    - Taizhou Hospital Of Zhejiang Province
    - Principal Investigator:
      
      Dongqing LV
  - Linyi, China, 276001
    - Recruiting
    - Linyi Cancer Hospital
    - Principal Investigator:
      
      Jianhua Shi
    - Contact:
      
      Phone Number: 15963998868
  - Liuzhou, China, 545006
    - Recruiting
    - Liuzhou People's Hospital
    - Principal Investigator:
      
      Min Li
  - Nanchang, China, 330006
    - Recruiting
    - The First Affiliated Hospital of Nanchang University
    - Principal Investigator:
      
      Wei Zuo
  - Nanjing, China, 210012
    - Recruiting
    - Nanjing First Hospital
    - Principal Investigator:
      
      Surong Fang
  - Shanghai, China, 200030
    - Recruiting
    - Shanghai Chest Hospital
    - Principal Investigator:
      
      Shun Lu
    - Contact:
      
      Phone Number: 8613601813062
  - Tianjin, China, 300060
    - Recruiting
    - Tianjin Medical University Cancer Institute & Hospital
    - Principal Investigator:
      
      Dingzhi Huang
    - Contact:
      
      Phone Number: 18622221232
  - Wuhan, China, 430060
    - Recruiting
    - Renmin Hospital of Wuhan University
    - Principal Investigator:
      
      Qibin Song
  - Wuhan, China, 430030
    - Recruiting
    - Tongji Hospital Tongji Medical,Science & Technology
    - Principal Investigator:
      
      Qian Chu
  - Wuhan, China, 430048
    - Recruiting
    - Wuhan Union Hospital
    - Principal Investigator:
      
      Xiaorong Dong
  - Wuhu, China, 241001
    - Recruiting
    - Wannan Medical College Yijishan Hospital
    - Principal Investigator:
      
      Xingwu Chen
  - Xi'an, China, 710061
    - Recruiting
    - The First Affiliated Hospital of Xi'an Jiaotong University
    - Principal Investigator:
      
      Yu Yao
  - Xiangyang, China, 441021
    - Recruiting
    - Xiangyang Central Hospital
    - Principal Investigator:
      
      Tienan Yi
  - Yichang, China, 443003
    - Recruiting
    - Yichang Central People's Hospital
    - Principal Investigator:
      
      Xinhua Xu
  - Zhanjiang, China, 524001
    - Recruiting
    - Affiliated Hospital of Guangdong Medical University
    - Principal Investigator:
      
      Shujun Li
  - Zhuzhou, China, 412007
    - Recruiting
    - ZhuZhou Central Hospital
    - Principal Investigator:
      
      Yanchao Liang
  - Ürümqi, China, 830000
    - Recruiting
    - Xinjiang Medical University Cancer Hospital - Urumqi
    - Principal Investigator:
      
      Chunling Liu
Czechia
- - Ostrava, Czechia, 703 84
    - Recruiting
    - Nemocnice AGEL Ostrava - Vitkovice a.s.
    - Principal Investigator:
      
      Jaromir Roubec
  - Prague, Czechia, 180 81
    - Recruiting
    - Fakultni nemocnice Bulovka
    - Principal Investigator:
      
      Jana Krejci
    - Contact:
      
      Phone Number: 420607533688
Denmark
- - Roskilde, Denmark, 4000
    - Recruiting
    - Roskilde University Hospital
    - Principal Investigator:
      
      Vladimira Horvat
France
- - Avignon, France, 84918
    - Recruiting
    - Sainte Catherine Institut du Cancer Avignon Provence
    - Principal Investigator:
      
      Hachmi AIT MOHAND SAID
  - Bron, France, 69677
    - Recruiting
    - Hospices Civils de Lyon - Hopital Louis Pradel
    - Principal Investigator:
      
      Michael Duruisseaux
  - Lille, France, 59037
    - Recruiting
    - CHU Lille - Institut Coeur Poumon
    - Principal Investigator:
      
      Alexis Cortot
    - Contact:
      
      Phone Number: 0320444998
  - Lyon Cedex08, France, 69373
    - Recruiting
    - Centre Leon Berard
    - Principal Investigator:
      
      Maurice Perol
    - Contact:
      
      Phone Number: 33426556761
  - Nice, France, 06189
    - Recruiting
    - Centre Antoine-Lacassagne
    - Principal Investigator:
      
      Victoria ferrari
    - Contact:
      
      Phone Number: 0492031324
  - Paris, France, 75248
    - Recruiting
    - Institut Curie
    - Principal Investigator:
      
      nicolas girard
    - Contact:
      
      Phone Number: 33624456290
  - Pessac, France, 33600
    - Recruiting
    - CHU Bordeaux Haut-Leveque
    - Principal Investigator:
      
      Remi Veillon
  - Poitiers, France, 86021
    - Recruiting
    - Centre Hospitalier Universitaire de Poitiers
    - Principal Investigator:
      
      Clotilde Deldycke
  - Reims, France, 51726
    - Recruiting
    - Institut Jean Godinot
    - Principal Investigator:
      
      Amélie Lemoine
  - Rennes, France, 35033
    - Recruiting
    - Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou
    - Principal Investigator:
      
      Herve Lena
  - Saint-Herblain, France, 44805
    - Recruiting
    - Institut de Cancérologie de l'Ouest
    - Principal Investigator:
      
      Sandrine Hiret
    - Contact:
      
      Phone Number: 33240679978
  - Strasbourg, France, 67091
    - Recruiting
    - Nouvel Hôpital Civil (NHC)
    - Principal Investigator:
      
      Celine Mascaux
  - Suresnes, France, 92151
    - Recruiting
    - Hôpital Foch
    - Principal Investigator:
      
      Jaafar Bennouna
    - Contact:
      
      Phone Number: 33 1 46 25 24 63
  - Toulon, France, 83100
    - Recruiting
    - Centre Hospitalier intercommunal de Toulon La Seyne sur Mer
    - Principal Investigator:
      
      Clarisse Audigier-Valette
  - Toulouse, France, 31059
    - Recruiting
    - CHU de Toulouse - Hôpital Larrey
    - Principal Investigator:
      
      Julien Mazieres
    - Contact:
      
      Phone Number: 335677718
  - Vandœuvre-lès-Nancy, France, 54511
    - Recruiting
    - Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois
    - Principal Investigator:
      
      Bertrand Mennecier
  - Vantoux, France, 57070
    - Recruiting
    - Hopital Robert Schuman
    - Principal Investigator:
      
      Julie Perrin
  - Villejuif, France, 94800
    - Recruiting
    - Gustave Roussy
    - Principal Investigator:
      
      Fabrice Barlesi
Germany
- - Berlin, Germany, 13125
    - Recruiting
    - Evangelische Lungenklinik Berlin
    - Principal Investigator:
      
      Christian Grohe
  - Berlin, Germany, 13353
    - Recruiting
    - Charité Campus Virchow-Klinikum
    - Principal Investigator:
      
      Nikolaj Frost
    - Contact:
      
      Phone Number: 004930450553044
  - Berlin, Germany, 14165
    - Recruiting
    - Helios Klinikum Emil von Behring Berlin-Zehlendorf
    - Principal Investigator:
      
      Jens Kollmeier
  - Chemnitz, Germany, 09116
    - Recruiting
    - Klinikum Chemnitz
    - Principal Investigator:
      
      Stefan Hammerschmidt
    - Contact:
      
      Phone Number: 4937133343550
  - Cologne, Germany, 50677
    - Recruiting
    - MV-Zentrum für Onkologie und Hämatologie
    - Principal Investigator:
      
      Jan-Phillip Weber
  - Donauwörth, Germany, 86609
    - Recruiting
    - Onkologiezentrum Donauwörth
    - Principal Investigator:
      
      Bastian Fleischmann
    - Contact:
      
      Phone Number: 49990629993911
  - Erfurt, Germany, 99089
    - Recruiting
    - HELIOS Klinikum Erfurt
    - Principal Investigator:
      
      Eva-Maria Barkowsky
    - Contact:
      
      Phone Number: 03617812586
  - Freiburg im Breisgau, Germany, 79106
    - Recruiting
    - Universitaetsklinikum Freiburg
    - Principal Investigator:
      
      Justyna Rawluk
    - Contact:
      
      Phone Number: 0049 761 27036630
  - Gauting, Germany, 82131
    - Recruiting
    - Asklepios Fachkliniken München-Gauting
    - Principal Investigator:
      
      Niels Reinmuth
    - Contact:
      
      Phone Number: 004989857914001
  - Georgsmarienhütte, Germany, 49124
    - Recruiting
    - Franziskus-Hospital Harderberg
    - Principal Investigator:
      
      Petra Hoffknecht
  - Großhansdorf, Germany, 22927
    - Recruiting
    - LungenClinic Grosshansdorf
    - Principal Investigator:
      
      Martin Reck
  - Halle, Germany, 06120
    - Recruiting
    - Krankenhaus Martha-Maria Halle-Dölau
    - Principal Investigator:
      
      Miriam Moeller
  - Hamburg, Germany, 21075
    - Recruiting
    - Asklepios Klinik Harburg
    - Principal Investigator:
      
      Claas Wesseler
  - Hamburg, Germany, 20251
    - Recruiting
    - Hämato-Onkologie Hamburg, Prof. Laack und Partner
    - Principal Investigator:
      
      Eckart Laack
    - Contact:
      
      Phone Number: 4940280065620
  - Heidelberg, Germany, 69126
    - Recruiting
    - Thoraxklinik-Heidelberg gGmbH
    - Principal Investigator:
      
      Helge Bischoff
    - Contact:
      
      Phone Number: 49 6221 3968304
  - Münster, Germany, 48149
    - Recruiting
    - Universitätsklinikum Münster - Albert Schweitzer Campus
    - Contact:
      
      Phone Number: 492518352712
    - Principal Investigator:
      
      Annalen Bleckmann
  - Nuremberg, Germany, 90419
    - Recruiting
    - Klinikum Nürnberg Nord
    - Contact:
      
      Phone Number: 0911398114963
    - Principal Investigator:
      
      Markus Horneber
  - Tübingen, Germany, 72076
    - Recruiting
    - Universitaetsklinikum Tuebingen
    - Contact:
      
      Phone Number: 4970712982711
    - Principal Investigator:
      
      Thorben Gross
Greece
- - Athens, Greece, 11527
    - Recruiting
    - Sotiria Thoracic Diseases Hospital of Athens
    - Principal Investigator:
      
      Konstantinos Syrigos
    - Contact:
      
      Phone Number: 302107700220
  - Athens, Greece, 115 22
    - Recruiting
    - Agios Savvas Regional Cancer Hospital
    - Principal Investigator:
      
      ANASTASIOS GRIVAS
  - Athens, Greece, 115 26
    - Recruiting
    - Errikos Dunant Hospital Center
    - Principal Investigator:
      
      IOANNIS MOUNTZIOS
  - Chaïdári, Greece, 12462
    - Recruiting
    - Attikon General University Hospital
    - Contact:
      
      Phone Number: 302105831265
    - Principal Investigator:
      
      Amanda Psyrri
  - Heraklion, Greece, 715 00
    - Recruiting
    - University General Hospital of Heraklion
    - Principal Investigator:
      
      Dimitrios Mavroudis
    - Contact:
      
      Phone Number: 2810-392750
  - Pátrai, Greece, 26504
    - Recruiting
    - University Hospital of Patras
    - Contact:
      
      Phone Number: 302610999791
    - Principal Investigator:
      
      Angelos Koutras
  - Thessaloniki, Greece, 570 01
    - Recruiting
    - European Interbalkan Medical Center
    - Principal Investigator:
      
      Sofia Baka
  - Thessaloniki, Greece, 540 07
    - Recruiting
    - "Theagenio" Cancer Hospital of Thessaloniki
    - Principal Investigator:
      
      Grigorios Rallis
    - Contact:
      
      Phone Number: 302310898607
  - Thessaloniki, Greece, 570 10
    - Recruiting
    - G. Papanikolaou General Hospital
    - Contact:
      
      Phone Number: 302312307278
    - Principal Investigator:
      
      Dionisios Spyratos
Hungary
- - Budapest, Hungary, 1122
    - Recruiting
    - Orszagos Onkologiai Intezet
    - Principal Investigator:
      
      Tunde Nagy
  - Budapest, Hungary, 1121
    - Recruiting
    - Orszagos Koranyi Pulmonologiai Intezet
    - Principal Investigator:
      
      Szabolcs Soter
  - Budapest, Hungary, 1145
    - Recruiting
    - Budapesti Uzsoki Utcai Kórház
    - Principal Investigator:
      
      Csaba Mathe
    - Contact:
      
      Phone Number: +3614673852
  - Farkasgyepű, Hungary, 8582
    - Recruiting
    - Farkasgyepui Tudogyogyintezet
    - Principal Investigator:
      
      Zsolt Kiraly
  - Kecskemét, Hungary, 6000
    - Recruiting
    - Bacs-Kiskun Megyei Korhaz
    - Principal Investigator:
      
      Zsolt Horvath
    - Contact:
      
      Phone Number: 3676516719
India
- - Ahmedabad, India, 380054
    - Recruiting
    - Hemato Oncology Clinic
    - Principal Investigator:
      
      Chirag Desai
    - Contact:
      
      Phone Number: 09824047561
  - Belagavi, India, 590010
    - Recruiting
    - KLES Dr. Prabhakar Kore Hospital & M.R.C
    - Contact:
      
      Phone Number: 09448111913
    - Principal Investigator:
      
      Rohan Bhise
  - Bengaluru, India, 560027
    - Recruiting
    - SRV Hospitals
    - Principal Investigator:
      
      Lokesh K.N
  - Bhubaneswar, India, 751019
    - Recruiting
    - All India Institute of Medical Sciences
    - Contact:
      
      Phone Number: 7008651823
    - Principal Investigator:
      
      Sourav Mishra
  - Coimbatore, India, 641012
    - Recruiting
    - Ashwin Hospital
    - Contact:
      
      Phone Number: 9884457106
    - Principal Investigator:
      
      Prabagar Manickam
  - Hyderabad, India, 500082
    - Recruiting
    - Nizam's Institute of Medical Sciences
    - Principal Investigator:
      
      Sadashivudu Gundeti
    - Contact:
      
      Phone Number: +919440911865
  - Karad, India, 415539
    - Recruiting
    - Krishna Institute of Medical Sciences - Karad
    - Principal Investigator:
      
      Rashmi Gudur
  - Kolhāpur, India, 416234
    - Recruiting
    - Kolhapur Cancer Centre Private Limited
    - Principal Investigator:
      
      Praveen Adusumilli
  - Nashik, India, 422001
    - Recruiting
    - HCG Manavata Cancer Centre
    - Principal Investigator:
      
      Dr. Aman Sondoule
  - Navi Mumbai, India, 410210
    - Recruiting
    - Advanced Centre for Treatment Research and Education in Cancer
    - Principal Investigator:
      
      Amit Joshi
    - Contact:
      
      Phone Number: 9769331525
  - Puducherry, India, 605006
    - Recruiting
    - Jawaharlal Institute Of Postgraduate Medical Education And Research
    - Principal Investigator:
      
      Prasanth Ganesan
  - Pune, India, 411057
    - Recruiting
    - Lifepoint Multispeciality Hospital
    - Contact:
      
      Phone Number: 02066434366
    - Principal Investigator:
      
      Ashwin Rajbhoj
  - Pune, India, 411001
    - Recruiting
    - Grant Medical Foundation - Ruby Hall Clinic
    - Contact:
      
      Phone Number: 02066455495
    - Principal Investigator:
      
      Minish Jain
  - Pune, India, 411004
    - Recruiting
    - Sahyadri Super Speciality Hospital
    - Principal Investigator:
      
      Tushar Patil
  - Thiruvananthapuram, India, 695011
    - Recruiting
    - Regional Cancer Centre - Thiruvananthapuram
    - Principal Investigator:
      
      Anoop Manoharan
  - Udaipur, India, 313001
    - Recruiting
    - Pacific Medical College & Hospital
    - Principal Investigator:
      
      Manoj Mahajan
  - Varanasi, India, 221002
    - Recruiting
    - Tata Memorial Centre - Homi Bhabha Cancer Hospital
    - Principal Investigator:
      
      Akhil Kapoor
    - Contact:
      
      Phone Number: 0542 2517699 ext 1001
  - Visakhapatnam, India, 530017
    - Recruiting
    - Mahatma Gandhi Cancer Hospital and Research Institute
    - Principal Investigator:
      
      YEDLA PRIYA
    - Contact:
      
      Phone Number: 9640953911
Italy
- - Bari, Italy, 70124
    - Recruiting
    - Instituto Tumori Giovanni Paolo II
    - Principal Investigator:
      
      Domenico Galetta
    - Contact:
      
      Phone Number: 39 080 5555442
  - Bologna, Italy, 40138
    - Recruiting
    - IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola
    - Principal Investigator:
      
      Andrea Ardizzoni
    - Contact:
      
      Phone Number: 390512142204
  - Catania, Italy, 95123
    - Recruiting
    - Policlinico "G. Rodolico"
    - Principal Investigator:
      
      HECTOR SOTO PARRA
    - Contact:
      
      Phone Number: 390953781496
  - Milan, Italy, 20133
    - Recruiting
    - Fondazione IRCCS Istituto Nazionale Dei Tumori
    - Principal Investigator:
      
      Giuseppe Lo Russo
    - Contact:
      
      Phone Number: 390223903829
  - Naples, Italy, 80131
    - Recruiting
    - Istituto Nazionale Tumori IRCCS Fondazione Pascale
    - Principal Investigator:
      
      Alessandro Morabito
    - Contact:
      
      Phone Number: 390817770291
  - Padova, Italy, 35128
    - Recruiting
    - Istituto Oncologico Veneto IRCCS
    - Principal Investigator:
      
      Giulia Pasello
    - Contact:
      
      Phone Number: 00390498215608
  - Roma, Italy, 00168
    - Recruiting
    - Fondazione Policlinico Universitario Agostino Gemelli
    - Principal Investigator:
      
      Emilio Bria
  - Rome, Italy, 00144
    - Recruiting
    - Istituto Nazionale Tumori Regina Elena
    - Principal Investigator:
      
      Federico Cappuzzo
    - Contact:
      
      Phone Number: 390652665698
  - Varese, Italy, 21100
    - Recruiting
    - Ospedale di Circolo e Fondazione Macchi Varese
    - Contact:
      
      Phone Number: +39 0332278558
    - Principal Investigator:
      
      Veronica Crespi
  - Verona, Italy, 37126
    - Recruiting
    - Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Trento
    - Contact:
      
      Phone Number: 3904518123515
    - Principal Investigator:
      
      SARA PILOTTO
Japan
- - Asahikawa, Japan, 0708644
    - Recruiting
    - National Hospital Organization Asahikawa Medical Center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Yuka Fujita
  - Bunkyō City, Japan, 113-8431
    - Recruiting
    - Juntendo University Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Takehito Shukuya
  - Bunkyō City, Japan, 113-8677
    - Recruiting
    - Tokyo Metropolitan Komagome Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Kageaki Watanabe
  - Fukuoka, Japan, 812-8582
    - Recruiting
    - Kyushu University Hospital
    - Principal Investigator:
      
      Isamu Okamoto
    - Contact:
      
      Phone Number: 81120023812
  - Fukuoka, Japan, 811-1395
    - Recruiting
    - National Hospital Organization Kyushu Cancer Center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Masafumi Yamaguchi
  - Hidaka, Japan, 350-1298
    - Recruiting
    - Saitama Medical University International Medical Center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Hisao Imai
  - Himeji, Japan, 670-8520
    - Recruiting
    - Himeji Medical Center
    - Principal Investigator:
      
      Tetsuji Kawamura
    - Contact:
      
      Phone Number: 81120023812
  - Hirakata, Japan, 573-1191
    - Recruiting
    - Kansai Medical University Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Takayasu Kurata
  - Kanazawa, Japan, 920-8641
    - Recruiting
    - Kanazawa University Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Shinji Takeuchi
  - Kasama, Japan, 309-1793
    - Recruiting
    - Ibaraki Prefectural Central Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Takayuki Kaburagi
  - Kashiwa, Japan, 277-8577
    - Recruiting
    - National Cancer Center Hospital East
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Koichi Goto
  - Kobe, Japan, 650-0047
    - Recruiting
    - Kobe City Medical Center General Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Yuki Sato
  - Kyoto, Japan, 602-8566
    - Recruiting
    - University Hospital,Kyoto Prefectural University of Medicine
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Tadaaki Yamada
  - Kōtō City, Japan, 135-8550
    - Recruiting
    - Japanese Foundation for Cancer Research
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Ryo Ariyasu
  - Matsuyama, Japan, 791-0280
    - Recruiting
    - National Hospital Organization Shikoku Cancer Center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Yuka Kato
  - Nagaizumi-cho,Sunto-gun, Japan, 411-8777
    - Recruiting
    - Shizuoka Cancer Center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Tateaki Naito
  - Nagasaki, Japan, 852-8501
    - Recruiting
    - Nagasaki University Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Takemoto Shinnosuke
  - Nagoya, Japan, 464-8681
    - Recruiting
    - Aichi Cancer Center Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Yutaka Fujiwara
  - Natori, Japan, 981-1293
    - Recruiting
    - Miyagi Cancer Center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Tatsuro Fukuhara
  - Niigata, Japan, 951-8566
    - Recruiting
    - Niigata Cancer Center Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Hiroshi Tanaka
  - Okayama, Japan, 700-8558
    - Recruiting
    - Okayama University Hospital
    - Principal Investigator:
      
      Kadoaki Ohashi
    - Contact:
      
      Phone Number: 81120023812
  - Sakai, Japan, 591-8555
    - Recruiting
    - National Hospital Organization Kinki-Chuo Chest Medical Center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Kyoichi Okishio
  - Sakai, Japan, 590-0197
    - Recruiting
    - Kindai University Hospital- Osakasayama Campus
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Takayuki Takahama
  - Sapporo, Japan, 060-8648
    - Recruiting
    - Hokkaido University Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Hidenori Kitai
  - Ube, Japan, 755-0241
    - Recruiting
    - National Hospital Organization Yamaguchi Ube Medical Center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Sho Uehara
  - Utsunomiya, Japan, 320-0834
    - Recruiting
    - Tochigi Cancer Center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Takashi Kasai
  - Wakayama, Japan, 641-8510
    - Recruiting
    - Wakayama Medical University Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Eri Takase
  - Yokohama, Japan, 236-0051
    - Recruiting
    - Kanagawa Cardiovascular and Respiratory Center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Tomohisa Baba
  - Yokohama, Japan, 2418515
    - Recruiting
    - Kanagawa cancer center
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Seigo Katakura
  - Yonago, Japan, 683-8504
    - Recruiting
    - Tottori University Hospital
    - Contact:
      
      Phone Number: 81120023812
    - Principal Investigator:
      
      Tomohiro Sakamoto
Mexico
- - Guadalajara, Mexico, 44680
    - Recruiting
    - Actualidad Basada en la Investigación del Cáncer
    - Principal Investigator:
      
      Emmanuel de la Mora Jimenez
    - Contact:
      
      Phone Number: 3316395372
  - Guadalajara, Mexico, 44670
    - Recruiting
    - PanAmerican Clinical Research - Guadalajara
    - Principal Investigator:
      
      Emilio Murillo
  - Guadalajara, Mexico, 44630
    - Recruiting
    - CIO - Centro de Inmuno-Oncología de Occidente
    - Contact:
      
      Phone Number: +523330447001
    - Principal Investigator:
      
      Noel Luna-Romero
  - Guadalajara, Mexico, 44680
    - Recruiting
    - Renati Innovation
    - Principal Investigator:
      
      Carlos Zuloaga Fernandez del Valle
  - Juriquilla, Mexico, 76230
    - Recruiting
    - Health Pharma Querétaro
    - Principal Investigator:
      
      Jordi Guzmán Casta
  - León, Mexico, 37178
    - Recruiting
    - Preparaciones Oncológicas S.C.
    - Contact:
      
      Phone Number: 4776439745
    - Principal Investigator:
      
      Jose Gonzalez Trujillo
  - Mexico City, Mexico, 03100
    - Recruiting
    - Health Pharma Professional Research S.A. de C.V:
    - Contact:
      
      Phone Number: +5215529002732
    - Principal Investigator:
      
      Jorge Alatorre Alexander
  - Mexico City, Mexico, 11819
    - Recruiting
    - Higiea Oncologia
    - Contact:
      
      Phone Number: 525552731712
    - Principal Investigator:
      
      Manuel Magallanes Maciel
  - Monterrey, Mexico, 64460
    - Recruiting
    - Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
    - Principal Investigator:
      
      Victor Oyervides Juarez
  - Monterrey, Mexico, 64623
    - Recruiting
    - Avix Investigación Clinica, S.C.
    - Contact:
      
      Phone Number: 528181431112
    - Principal Investigator:
      
      Julia Saenz Frias
  - Oaxaca City, Mexico, 68020
    - Recruiting
    - Centro de Investigacion Clinica de Oaxaca
    - Contact:
      
      Phone Number: +529516035559
    - Principal Investigator:
      
      Yolanda Bautista Aragon
  - Puebla City, Mexico, 72530
    - Recruiting
    - Clinica Integral Internacional de Oncología
    - Principal Investigator:
      
      Iván González Espinoza
  - San Pedro Garza García, Mexico, 66220
    - Not yet recruiting
    - Oncare - Unidad Valle
    - Contact:
      
      Phone Number: 82188555
    - Principal Investigator:
      
      Luis Cancel
  - Veracruz, Mexico, 91900
    - Recruiting
    - Arké SMO S.A de C.V
    - Contact:
      
      Phone Number: 2299314102
    - Principal Investigator:
      
      Pedro Arredondo Ruiz
Netherlands
- - 's-Hertogenbosch, Netherlands, 5223 GZ
    - Recruiting
    - Jeroen Bosch Hospital
    - Principal Investigator:
      
      Bianca Veggel
    - Contact:
      
      Phone Number: 0031735532463
  - Enschede, Netherlands, 7512 KZ
    - Recruiting
    - Medisch Spectrum Twente
    - Contact:
      
      Phone Number: 0534872610
    - Principal Investigator:
      
      Albert Polman
  - Harderwijk, Netherlands, 3844 DG
    - Recruiting
    - Ziekenhuis St. Jansdal
    - Principal Investigator:
      
      L.N. Boom
    - Contact:
      
      Phone Number: 0031 341 463504
  - Hilversum, Netherlands, 1213 XZ
    - Recruiting
    - Tergooiziekenhuizen, locatie Hilversum
    - Principal Investigator:
      
      Jan Maarten van Haarst
    - Contact:
      
      Phone Number: 0887531753
  - Leeuwarden, Netherlands, 8934 AD
    - Recruiting
    - Frisius Medisch Centrum
    - Contact:
      
      Phone Number: 0031582863103
    - Principal Investigator:
      
      Rolof Gijtenbeek
  - Leiden, Netherlands, 2333 ZA
    - Recruiting
    - Leids Universitair Medisch Centrum
    - Principal Investigator:
      
      Egbert Smit
    - Contact:
      
      Phone Number: 31715262950
  - Rotterdam, Netherlands, 3015 GD
    - Recruiting
    - Erasmus Medisch Centrum
    - Principal Investigator:
      
      Anne Marie C. Dingemans
    - Contact:
      
      Phone Number: 31107040704
  - Tilburg, Netherlands, 5022 GC
    - Recruiting
    - ETZ Elisabeth
    - Contact:
      
      Phone Number: 31132213101
    - Principal Investigator:
      
      Mart Schiefer
  - Utrecht, Netherlands, 3543 AZ
    - Recruiting
    - St. Antonius Ziekenhuis, locatie Utrecht
    - Contact:
      
      Phone Number: 31883201410
    - Principal Investigator:
      
      Lisanne Kastelijn
Norway
- - Bergen, Norway, 5021
    - Recruiting
    - Haukeland Universitetssjukehus
    - Principal Investigator:
      
      Christina Aamelfot
    - Contact:
      
      Phone Number: 4755970762
  - Drammen, Norway, 3004
    - Recruiting
    - Drammen Sykehus, Vestre Viken HF
    - Principal Investigator:
      
      Odd Terje Brustugun
    - Contact:
      
      Phone Number: 4732000240
  - Gjøvik, Norway, 2819
    - Recruiting
    - Sykehuset Innlandet HF Gjøvik
    - Principal Investigator:
      
      Daniel Heinrich
    - Contact:
      
      Phone Number: 4791395554
  - Lørenskog, Norway, 1478
    - Recruiting
    - Akershus Universitetssykehus
    - Principal Investigator:
      
      Kirill Neumann
    - Contact:
      
      Phone Number: 0047 679 66 079
  - Oslo, Norway, 0379
    - Recruiting
    - Oslo universitetssykehus, Radiumhospitalet
    - Contact:
      
      Phone Number: 47 02770
    - Principal Investigator:
      
      Vilde Haakensen
  - Stavanger, Norway, 4021
    - Recruiting
    - Stavanger Universitetssykehus
    - Principal Investigator:
      
      Edie Gina Barrera
  - Trondheim, Norway, 7030
    - Recruiting
    - St. Olavs Hospital
    - Principal Investigator:
      
      Bjørn Grønberg
Poland
- - Kielce, Poland, 25-734
    - Recruiting
    - Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zaklad Opieki Zdrowotnej
    - Principal Investigator:
      
      Kinga Szydziak-Zwierzynska
    - Contact:
      
      Phone Number: 48 41 3674809
  - Szczecin, Poland, 70-419
    - Recruiting
    - One Day Med
    - Principal Investigator:
      
      Piotr Serwatowski
    - Contact:
      
      Phone Number: 48914427209
  - Torun, Poland, 87-100
    - Recruiting
    - MICS Centrum Medyczne Torun
    - Principal Investigator:
      
      Justyna Wietrzynska
    - Contact:
      
      Phone Number: 48563004384
Portugal
- - Coimbra, Portugal, 3004-561
    - Recruiting
    - Centro Hospitalar e Universitário de Coimbra
    - Principal Investigator:
      
      Ana Figueiredo
  - Lisbon, Portugal, 1400-038
    - Recruiting
    - Champalimaud Foundation
    - Principal Investigator:
      
      Susana Simoes
  - Lisbon, Portugal, 1769-001
    - Recruiting
    - Hospital Pulido Valente
    - Principal Investigator:
      
      Paula Alves
  - Lisbon, Portugal, 1500-650
    - Recruiting
    - Hospital da Luz Lisboa
    - Principal Investigator:
      
      Joao Moreira Pinto
  - Porto, Portugal, 4099-001
    - Recruiting
    - Centro Hospitalar do Porto - Hospital de Santo António
    - Principal Investigator:
      
      Antonio Araujo
    - Contact:
      
      Phone Number: 222077500
  - Porto, Portugal, 4200-072
    - Recruiting
    - Instituto Portugues de Oncologia do Porto Francisco Gentil, EPE
    - Principal Investigator:
      
      Cristina Oliveira
  - Porto, Portugal, 4100-180
    - Recruiting
    - Hospital CUF Porto
    - Contact:
      
      Phone Number: 220039029
    - Principal Investigator:
      
      Venceslau Hespanhol
Romania
- - Bucharest, Romania, 012292
    - Recruiting
    - Lotus-Med
    - Principal Investigator:
      
      Anca Zgura
    - Contact:
      
      Phone Number: 40751110005
  - Bucharest, Romania, 013812
    - Recruiting
    - SC Memorial Healthcare International SRL
    - Contact:
      
      Phone Number: 40721298677
    - Principal Investigator:
      
      Ingrid Iordan
  - Bucharest, Romania, 031422
    - Recruiting
    - Gral Medical Diagnostic Center
    - Contact:
      
      Phone Number: 40726273762
    - Principal Investigator:
      
      Cristina Tiut
  - Cluj-Napoca, Romania, 400015
    - Recruiting
    - Institutul Oncologic
    - Principal Investigator:
      
      Tudor Ciuleanu
  - Craiova, Romania, 200542
    - Recruiting
    - Centrul de Oncologie "Sfântul Nectarie"
    - Contact:
      
      Phone Number: 40727774974
    - Principal Investigator:
      
      Michael Schenker
  - Ovidiu, Romania, 905900
    - Recruiting
    - Ovidius Clinical Hospital OCH
    - Contact:
      
      Phone Number: 0724877013
    - Principal Investigator:
      
      Laura Mazilu
  - Timișoara, Romania, 300166
    - Recruiting
    - S C Oncocenter Oncologie Clinica S R L
    - Contact:
      
      Phone Number: 0040745146020
    - Principal Investigator:
      
      Roxana Scheusan
  - Timișoara, Romania, 300239
    - Recruiting
    - Cabinet Medical Oncomed
    - Contact:
      
      Phone Number: 40723401453
    - Principal Investigator:
      
      Mihaela Pasca-Fenesan
South Korea
- - Cheongju-si, South Korea, 28644
    - Recruiting
    - Chungbuk National University Hospital
    - Principal Investigator:
      
      Ki Hyeong Lee
  - Daegu, South Korea, 42601
    - Recruiting
    - Keimyung University Dongsan Hospital
    - Principal Investigator:
      
      Sun Hyo Park
    - Contact:
      
      Phone Number: 01063522096
  - Deagu, South Korea, 41404
    - Recruiting
    - Kyungpook National University Chilgok Hospital
    - Principal Investigator:
      
      Shin Yup Lee
  - Gangnam-gu, South Korea, 06273
    - Recruiting
    - Gangnam Severance Hospital, Yonsei University Health System
    - Principal Investigator:
      
      Yoon Soo Chang
  - Goyang-si, South Korea, 10408
    - Recruiting
    - National Cancer Center
    - Contact:
      
      Phone Number: 82319201154
    - Principal Investigator:
      
      Ji-Youn Han
  - Hwasun, South Korea, 58128
    - Recruiting
    - Chonnam National University Hwasun Hospital
    - Principal Investigator:
      
      Young-Chul Kim
  - Seoul, South Korea, 05505
    - Recruiting
    - Asan Medical Center
    - Principal Investigator:
      
      Chang Min Choi
  - Seoul, South Korea, 03722
    - Recruiting
    - Severance Hospital, Yonsei University Health System
    - Principal Investigator:
      
      Hye Ryun Kim
    - Contact:
      
      Phone Number: 82222284190
  - Seoul, South Korea, 06351
    - Recruiting
    - Samsung Medical Center
    - Principal Investigator:
      
      Se-Hoon Lee
  - Seoul, South Korea, 07345
    - Recruiting
    - The Catholic University of Korea, Yeouido St. Mary's Hospital
    - Principal Investigator:
      
      Chankwon Park
  - Seoul, South Korea, 02841
    - Recruiting
    - Korea University Anam Hospital
    - Principal Investigator:
      
      Yoon Ji Choi
    - Contact:
      
      Phone Number: 82-2-920-6267
  - Seoul, South Korea, 04763
    - Recruiting
    - Hanyang University Seoul Hospital
    - Principal Investigator:
      
      Dong-Woo Han
  - Seoul, South Korea, 08308
    - Recruiting
    - Korea University Guro Hospital
    - Principal Investigator:
      
      Sung Yong Lee
  - Suwon, South Korea, 16247
    - Recruiting
    - The Catholic University of Korea St. Vincent's Hospital
    - Principal Investigator:
      
      Byoung Yong Shim
    - Contact:
      
      Phone Number: 82-31-881-8906
  - Yangsan, South Korea, 50612
    - Recruiting
    - Pusan National University Yangsan Hospital
    - Principal Investigator:
      
      Seong Hoon Yoon
Spain
- - A Coruña, Spain, 15006
    - Recruiting
    - CHUAC-Hospital Teresa Herrera
    - Principal Investigator:
      
      Maria Garcia Campelo
  - Badajoz, Spain, 06006
    - Recruiting
    - Hospital Infanta Cristina
    - Principal Investigator:
      
      Marta Gonzalez Cordero
    - Contact:
      
      Phone Number: 924218040
  - Barakaldo, Spain, 48903
    - Recruiting
    - OSI Ezkerraldea-Enkarterri-Cruces - Hospital Universitario Cruces
    - Principal Investigator:
      
      Eider Azkona Uribelarrea
    - Contact:
      
      Phone Number: 94 60006399
  - Barcelona, Spain, 08035
    - Recruiting
    - Hospital Universitari Vall d'Hebron
    - Principal Investigator:
      
      Enriqueta Felip Font
    - Contact:
      
      Phone Number: 34932746085
  - Barcelona, Spain, 08028
    - Recruiting
    - Hospital Universitari Dexeus
    - Principal Investigator:
      
      ANDRES AGUILAR
  - Barcelona, Spain, 08003
    - Recruiting
    - Parc de Salut Mar - Hospital del Mar
    - Principal Investigator:
      
      Edurne Arriola Aperribay
    - Contact:
      
      Phone Number: 34932483137
  - Hospitalet, Spain, 08907
    - Recruiting
    - Instituto Catalan de Oncologia - Hospital Duran i Reynals
    - Principal Investigator:
      
      Ernest Nadal Alforja
    - Contact:
      
      Phone Number: 932607744
  - Jerez de la Frontera, Spain, 11407
    - Recruiting
    - Hospital Jerez de la Frontera
    - Principal Investigator:
      
      Jesus Corral Jaime
  - Las Palmas de Gran Canaria, Spain, 35016
    - Recruiting
    - Hospital Insular de Gran Canaria
    - Principal Investigator:
      
      DELVYS RODRIGUEZ ABREU
    - Contact:
      
      Phone Number: 34928441738
  - León, Spain, 24071
    - Recruiting
    - Complejo Asistencial Universitario de León - Hospital de León
    - Principal Investigator:
      
      Soledad Valdivieso
  - Madrid, Spain, 28034
    - Recruiting
    - Hospital Universitario Ramon y Cajal
    - Principal Investigator:
      
      Pilar Garrido Lopez
    - Contact:
      
      Phone Number: (+34) 913368263
  - Madrid, Spain, 28041
    - Recruiting
    - Hospital Universitario 12 De Octubre
    - Principal Investigator:
      
      Luis Paz-Ares Rodriguez
    - Contact:
      
      Phone Number: 0034913908000
  - Málaga, Spain, 29011
    - Recruiting
    - H.R.U Málaga - Hospital General
    - Contact:
      
      Phone Number: 34951308130
    - Principal Investigator:
      
      María Vanesa Gutierrez Calderon
  - Palma, Spain, 07120
    - Recruiting
    - Hospital Universitari Son Espases
    - Principal Investigator:
      
      Aitor Azkarate Martinez
  - Pamplona, Spain, 31009
    - Recruiting
    - Complejo Hospitalario de Navarra
    - Principal Investigator:
      
      Maite Martinez Aguillo
  - Pozuelo de Alarcón, Spain, 28223
    - Recruiting
    - Hospital Universitario Quironsalud Madrid
    - Principal Investigator:
      
      Belen Rubio Viqueira
    - Contact:
      
      Phone Number: 34914521987
  - Santiago de Compostela, Spain, 15706
    - Recruiting
    - CHUS - Hospital Clinico Universitario
    - Contact:
      
      Phone Number: 981950511
    - Principal Investigator:
      
      Luis Leon Mateos
  - Seville, Spain, 41013
    - Recruiting
    - Hospital Universitario Virgen del Rocio
    - Contact:
      
      Phone Number: 955013068
    - Principal Investigator:
      
      Reyes Bernabe Caro
  - Valencia, Spain, 46010
    - Recruiting
    - Hospital Clinico de Valencia
    - Principal Investigator:
      
      Amelia Insa Molla
    - Contact:
      
      Phone Number: 961973500
  - Zaragoza, Spain, 50009
    - Recruiting
    - Hospital Clinico Universitario Lozano Blesa
    - Principal Investigator:
      
      Dolores Isla Casado
    - Contact:
      
      Phone Number: +34976765746
Sweden
- - Eskilstuna, Sweden, 631 88
    - Recruiting
    - Mälarsjukhuset
    - Principal Investigator:
      
      Andreas Nearchou
    - Contact:
      
      Phone Number: 0046700599120
  - Västerås, Sweden, 721 89
    - Recruiting
    - Västmanlands Sjukhus Västerås
    - Principal Investigator:
      
      David Sterner
Switzerland
- - Lausanne, Switzerland, 1011
    - Recruiting
    - CHUV (centre hospitalier universitaire vaudois)
    - Principal Investigator:
      
      Karim Abdelhamid
  - Winterthur, Switzerland, 8401
    - Recruiting
    - Kantonsspital Winterthur
    - Principal Investigator:
      
      Laetitia Mauti
    - Contact:
      
      Phone Number: 41522662373
Taiwan
- - Changhua County, Taiwan, 50006
    - Recruiting
    - Changhua Christian Hospital
    - Principal Investigator:
      
      Sheng-Hao Lin
    - Contact:
      
      Phone Number: +886-4-7238595 ext.3934
  - Chiayi City, Taiwan, 622
    - Recruiting
    - Buddhist Dalin Tzu Chi General Hospital
    - Principal Investigator:
      
      Chun-Liang Lai
  - Douliu, Taiwan, 640
    - Recruiting
    - National Taiwan University Hospital Yun-Lin Branch Dou-Liou Region
    - Principal Investigator:
      
      You-Yi Chen
  - Hualien City, Taiwan, 970
    - Recruiting
    - Hualien Tzu Chi Medical Center
    - Principal Investigator:
      
      Chih-Bin Lin
  - Kaohsiung City, Taiwan, 807
    - Recruiting
    - Kaohsiung Medical University Chung-Ho Memorial Hospital
    - Principal Investigator:
      
      Jen-Yu Hung
    - Contact:
      
      Phone Number: 88673121101-5651
  - Kaohsiung Niao Sung Dist, Taiwan, 83301
    - Recruiting
    - Chang Gung Memorial Hospital at Kaohsiung
    - Principal Investigator:
      
      Chin-Chou Wang
    - Contact:
      
      Phone Number: +886-7-7317123 ext. 8199
  - New Taipei City, Taiwan, 236
    - Recruiting
    - New Taipei Municipal TuCheng Hospital
    - Principal Investigator:
      
      Chiao-En Wu
    - Contact:
      
      Phone Number: 0975366098
  - Taichung, Taiwan, 402
    - Recruiting
    - Chung Shan Medical University Hospital
    - Principal Investigator:
      
      Gee-Chen Chang
    - Contact:
      
      Phone Number: 0424739595
  - Taichung, Taiwan, 407
    - Recruiting
    - Taichung Veterans General Hospital
    - Principal Investigator:
      
      Tsung-Ying Yang
    - Contact:
      
      Phone Number: 886-23592525(3259)
  - Tainan, Taiwan, 704
    - Recruiting
    - National Cheng Kung University Hospital
    - Principal Investigator:
      
      Chien-Chung Lin
  - Tainan, Taiwan, 71004
    - Recruiting
    - Chi Mei Medical Center
    - Principal Investigator:
      
      Yu-Hsuan Kuo
  - Tainan, Taiwan, 73657
    - Recruiting
    - Chi Mei Hospital - Liouying Branch
    - Principal Investigator:
      
      Wen-Tsung Huang
  - Taipei, Taiwan, 10002
    - Recruiting
    - National Taiwan University Hospital
    - Principal Investigator:
      
      Chia-Chi Lin
    - Contact:
      
      Phone Number: 886-2-2312-3456
  - Taipei, Taiwan, 11217
    - Recruiting
    - Taipei Veterans General Hospital
    - Principal Investigator:
      
      Chi-Lu Chiang
  - Taipei, Taiwan, 106
    - Recruiting
    - National Taiwan University Cancer Center (NTUCC)
    - Principal Investigator:
      
      Chih-Hsin Yang
    - Contact:
      
      Phone Number: 886-2-23123456
  - Taoyuan, Taiwan, 333
    - Recruiting
    - Chang Gung Medical Foundation-Linkou Branch
    - Principal Investigator:
      
      Cheng-Ta Yang
  - Zhubei, Taiwan, 302
    - Recruiting
    - National Taiwan University Hospital - Hsinchu branch
    - Principal Investigator:
      
      Jih-Hsiang Lee
    - Contact:
      
      Phone Number: 886-3-5326151 ext 34502
Turkey (Türkiye)
- - Adana, Turkey (Türkiye), 01140
    - Recruiting
    - Adana Medical Park Seyhan Hastanesi
    - Principal Investigator:
      
      Ahmet Sezer
    - Contact:
      
      Phone Number: 905333616939
  - Adana, Turkey (Türkiye), 01370
    - Recruiting
    - Adana City Hospital
    - Principal Investigator:
      
      Timucin Cil
    - Contact:
      
      Phone Number: 90538 609 92 02
  - Ankara, Turkey (Türkiye), 06800
    - Recruiting
    - Ankara Bilkent Sehir Hastanesi
    - Contact:
      
      Phone Number: 905555306271
    - Principal Investigator:
      
      Mehmet Ali Nahit Sendur
  - Ankara, Turkey (Türkiye), 06170
    - Recruiting
    - Ankara Etlik City Hospital
    - Contact:
      
      Phone Number: 05055718475
    - Principal Investigator:
      
      Berna Oksuzoglu
  - Ankara, Turkey (Türkiye), 06200
    - Recruiting
    - Abdurrahman Yurtaslan Ankara Oncology, education and Research Hospital
    - Principal Investigator:
      
      Cengiz Karacin
  - Antalya, Turkey (Türkiye), 07100
    - Not yet recruiting
    - Antalya Egitim ve Arastırma Hastanesi
    - Contact:
      
      Phone Number: 905336488217
    - Principal Investigator:
      
      Derya KIVRAK SALIM
  - Antalya, Turkey (Türkiye), 07090
    - Recruiting
    - Memorial Antalya Hospital
    - Principal Investigator:
      
      Mustafa Ozdogan
  - Antalya, Turkey (Türkiye), 07059
    - Recruiting
    - Akdeniz Universitesi Hastanesi
    - Principal Investigator:
      
      Sema Sezgin Goksu
    - Contact:
      
      Phone Number: 05052312377
  - Bursa, Turkey (Türkiye), 16059
    - Recruiting
    - Uludag Universitesi
    - Contact:
      
      Phone Number: 905336460546
    - Principal Investigator:
      
      Turkkan Evrensel
  - Diyarbakır, Turkey (Türkiye), 21200
    - Recruiting
    - Dicle Üniversitesi
    - Principal Investigator:
      
      Muhammet kaplan
    - Contact:
      
      Phone Number: 90 5337677131
  - Istanbul, Turkey (Türkiye), 34722
    - Recruiting
    - TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi
    - Principal Investigator:
      
      Mahmut Gumus
  - Istanbul, Turkey (Türkiye), 34295
    - Recruiting
    - İ.A.Ü VM Medical Park Florya Hastanesi
    - Contact:
      
      Phone Number: 905322480988
    - Principal Investigator:
      
      Irfan Cicin
  - Istanbul, Turkey (Türkiye), 34093
    - Recruiting
    - Bezmialem Vakf Üniversitesi
    - Principal Investigator:
      
      Haci Mehmet Turk
    - Contact:
      
      Phone Number: 05344299253
  - Izmir, Turkey (Türkiye), 35100
    - Recruiting
    - Ege Universitesi Hastanesi
    - Principal Investigator:
      
      Tuncay Goksel
    - Contact:
      
      Phone Number: 05322202675
  - Izmir, Turkey (Türkiye), 35360
    - Recruiting
    - zmir Katip Çelebi Üniversitesi Atatürk Eitim Ve Aratrma Hastanesi
    - Contact:
      
      Phone Number: 905324078648
    - Principal Investigator:
      
      Ahmet Alacacioglu
  - Kocaeli, Turkey (Türkiye), 41380
    - Recruiting
    - Kocaeli Üniversitesi
    - Principal Investigator:
      
      Devrim Cabuk
    - Contact:
      
      Phone Number: +905327650185
  - Samsun, Turkey (Türkiye), 55270
    - Recruiting
    - Ondokuz Mayıs Universitesi
    - Principal Investigator:
      
      Bahiddin Yilmaz
    - Contact:
      
      Phone Number: 90 532 599 28 25
United Kingdom
- - Aberdeen, United Kingdom, AB25 2ZN
    - Recruiting
    - Aberdeen Royal Infirmary
    - Principal Investigator:
      
      Andrew Duncan
  - Dundee, United Kingdom, DD1 9SY
    - Recruiting
    - Ninewells Hospital and Medical School
    - Principal Investigator:
      
      Hannah Lord
  - Huddersfield, United Kingdom, HD3 3EA
    - Recruiting
    - Huddersfield Royal Infirmary
    - Principal Investigator:
      
      Emma Rathbone
  - Leeds, United Kingdom, LS9 7TF
    - Recruiting
    - St James's University Hospital
    - Principal Investigator:
      
      Katy Clarke
  - Manchester, United Kingdom, M20 4BX
    - Recruiting
    - The Christie NHS Foundation Trust
    - Principal Investigator:
      
      Colin Lindsay
  - Northwood, United Kingdom, HA6 2RN
    - Recruiting
    - Mount Vernon Hospital
    - Principal Investigator:
      
      Andreas Polychronis
    - Contact:
      
      Phone Number: 02038262058
  - Sheffield, United Kingdom, S10 2SJ
    - Recruiting
    - Weston Park Hospital
    - Principal Investigator:
      
      Tathagata Das
  - Wolverhampton, United Kingdom, WV10 0QP
    - Recruiting
    - New Cross Hospital
    - Principal Investigator:
      
      Talha Hafeez
United States
- Alabama
  - Huntsville, Alabama, United States, 35805
    - Recruiting
    - Clearview Cancer Institute
    - Contact:
      
      Phone Number: 256-705-4224
    - Principal Investigator:
      
      Marshall Schreeder
- Arizona
  - Gilbert, Arizona, United States, 85234
    - Recruiting
    - Banner MD Anderson Cancer Center
    - Principal Investigator:
      
      Jiaxin Niu
  - Phoenix, Arizona, United States, 85006
    - Recruiting
    - Banner University Medical Center Phoenix
    - Principal Investigator:
      
      Jiaxin Niu
  - Tucson, Arizona, United States, 85719
    - Recruiting
    - The University of Arizona Cancer Center - North Campus
    - Principal Investigator:
      
      Linda Garland
    - Contact:
      
      Phone Number: 520-626-3434
- Arkansas
  - Springdale, Arkansas, United States, 72762
    - Recruiting
    - Highlands Oncology Group
    - Principal Investigator:
      
      Eric Schaefer
    - Contact:
      
      Phone Number: 479-872-8130
- California
  - Los Angeles, California, United States, 90048
    - Recruiting
    - Cedars-Sinai Medical Center
    - Principal Investigator:
      
      Kamya Sankar
  - Merced, California, United States, 95340
    - Recruiting
    - Mercy Cancer Center
    - Contact:
      
      Phone Number: 209-564-3607
    - Principal Investigator:
      
      Parminder Sidhu
  - Torrance, California, United States, 90502
    - Completed
    - Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
  - Walnut Creek, California, United States, 94598
    - Recruiting
    - BASS Cancer Center
    - Principal Investigator:
      
      Jewel Johl
- Colorado
  - Lone Tree, Colorado, United States, 80124
    - Recruiting
    - USO - Rocky Mountain Cancer Centers
    - Principal Investigator:
      
      Robert Jotte
    - Contact:
      
      Phone Number: 303-925-0700
- Connecticut
  - New Haven, Connecticut, United States, 06510
    - Recruiting
    - Yale University School of Medicine
    - Principal Investigator:
      
      So Yeon Kim
    - Contact:
      
      Phone Number: 475-306-2658
- District of Columbia
  - Washington D.C., District of Columbia, United States, 20016
    - Recruiting
    - Sibley Memorial Hospital
    - Principal Investigator:
      
      Kristen Marrone
- Florida
  - Hollywood, Florida, United States, 33024
    - Recruiting
    - Millennium Oncology Research Clinic
    - Contact:
      
      Phone Number: 954-450-1808
    - Principal Investigator:
      
      Isaac Levy
  - Jacksonville, Florida, United States, 32209
    - Recruiting
    - University of Florida - Jacksonville
    - Contact:
      
      Phone Number: 904-244-4292
    - Principal Investigator:
      
      Gregory Wynn
  - Miami, Florida, United States, 33176
    - Recruiting
    - Miami Cancer Institute at Baptist Health, Inc.
    - Principal Investigator:
      
      Bruna Pellini
  - Ocala, Florida, United States, 34474
    - Recruiting
    - Ocala Oncology Center PL DBA Florida Cancer Affiliates - Ocala
    - Contact:
      
      Phone Number: 352-732-4032
    - Principal Investigator:
      
      Ketan Doshi
  - St. Petersburg, Florida, United States, 33709
    - Recruiting
    - Comprehensive Hematology Oncology
    - Principal Investigator:
      
      Neeharika Makani
    - Contact:
      
      Phone Number: 727-344-6569
- Georgia
  - Athens, Georgia, United States, 30607
    - Recruiting
    - University Cancer & Blood Center, LLC
    - Principal Investigator:
      
      PETROS NIKOLINAKOS
    - Contact:
      
      Phone Number: 706-353-2990
  - Atlanta, Georgia, United States, 30322
    - Recruiting
    - Winship Cancer Institute, Emory University
    - Principal Investigator:
      
      Ticiana Leal
    - Contact:
      
      Phone Number: 404-251-5544
  - Atlanta, Georgia, United States, 30303
    - Recruiting
    - Emory University School of Medicine- Grady Campus
    - Principal Investigator:
      
      Ticiana Leal
    - Contact:
      
      Phone Number: 404-251-5544
- Illinois
  - Chicago, Illinois, United States, 60637
    - Recruiting
    - University of Chicago Hospital
    - Principal Investigator:
      
      Marina Garassino
    - Contact:
      
      Phone Number: 773-702-9901
  - Chicago, Illinois, United States, 60612
    - Recruiting
    - University of Illinois at Chicago
    - Principal Investigator:
      
      Frank Weinberg
  - Springfield, Illinois, United States, 62702
    - Recruiting
    - Springfield Clinic Main Campus
    - Principal Investigator:
      
      Preet Singh
- Indiana
  - Fort Wayne, Indiana, United States, 46845
    - Recruiting
    - Parkview Research Center at Parkview Regional Medical Center
    - Principal Investigator:
      
      patricia Rich
  - Indianapolis, Indiana, United States, 46202
    - Recruiting
    - Indiana University Melvin and Bren Simon Cancer Center
    - Principal Investigator:
      
      Gregory Durm
  - Indianapolis, Indiana, United States, 46237
    - Recruiting
    - Franciscan Health
    - Principal Investigator:
      
      Harsha Ranganath
    - Contact:
      
      Phone Number: 317-859-5252
  - Indianapolis, Indiana, United States, 46250
    - Recruiting
    - Community Cancer Center North
    - Principal Investigator:
      
      Natraj Ammakkanavar
    - Contact:
      
      Phone Number: 317-621-3858
- Kansas
  - Westwood, Kansas, United States, 66205
    - Recruiting
    - The University of Kansas Cancer Center - Westwood
    - Principal Investigator:
      
      Chao Huang
    - Contact:
      
      Phone Number: 913-588-6029
- Kentucky
  - Lexington, Kentucky, United States, 40536
    - Recruiting
    - University of Kentucky Chandler Medical Center
    - Contact:
      
      Phone Number: 859-257-9568
    - Principal Investigator:
      
      Susanne Arnold
  - Lexington, Kentucky, United States, 40509
    - Recruiting
    - CHI Saint Joseph Cancer Center - East
    - Principal Investigator:
      
      Nicola Jabbour
- Louisiana
  - Baton Rouge, Louisiana, United States, 70809
    - Recruiting
    - Mary Bird Perkins Cancer Center
    - Principal Investigator:
      
      Victor Lin
    - Contact:
      
      Phone Number: 225-215-1185
- Maryland
  - Baltimore, Maryland, United States, 21224
    - Recruiting
    - Johns Hopkins Bayview Medical Center
    - Principal Investigator:
      
      Kristen Marrone
  - Columbia, Maryland, United States, 21044
    - Recruiting
    - USO - Maryland Oncology Hematology
    - Principal Investigator:
      
      Benjamin Bridges
- Massachusetts
  - Boston, Massachusetts, United States, 02118
    - Recruiting
    - Boston Medical Center
    - Principal Investigator:
      
      Umit Tapan
    - Contact:
      
      Phone Number: 617-638-7584
  - Burlington, Massachusetts, United States, 01805
    - Recruiting
    - Lahey Hospital & Medical Center
    - Principal Investigator:
      
      Andrew Piper-Vallillo
    - Contact:
      
      Phone Number: 781-744-8400
- Michigan
  - Ann Arbor, Michigan, United States, 48109
    - Recruiting
    - University of Michigan
    - Principal Investigator:
      
      Angel Qin
  - Detroit, Michigan, United States, 48201
    - Recruiting
    - Karmanos Cancer Institute
    - Principal Investigator:
      
      Khalil Choucair
  - Grand Rapids, Michigan, United States, 49503
    - Recruiting
    - The Cancer & Hematology Centers
    - Principal Investigator:
      
      Eric Santos
- Minnesota
  - Minneapolis, Minnesota, United States, 55407
    - Recruiting
    - Allina Health Cancer Institute - Abbott Northwestern Hospital
    - Principal Investigator:
      
      Charlene Fares
  - Saint Paul, Minnesota, United States, 55101
    - Recruiting
    - HealthPartners Cancer Research Center
    - Principal Investigator:
      
      Kurt Demel
- Mississippi
  - Tupelo, Mississippi, United States, 38801
    - Recruiting
    - North Mississippi Hematology and Oncology Associates
    - Principal Investigator:
      
      Amit Jain
- Missouri
  - Springfield, Missouri, United States, 65807
    - Recruiting
    - Oncology Hematology Associates
    - Contact:
      
      Phone Number: 417-882-4880
    - Principal Investigator:
      
      Viran Holden
- Nevada
  - Las Vegas, Nevada, United States, 89169
    - Recruiting
    - Comprehensive Cancer Centers of Nevada
    - Principal Investigator:
      
      Liawaty Ho
- New Hampshire
  - Lebanon, New Hampshire, United States, 03756
    - Recruiting
    - Dartmouth-Hitchcock Medical Center
    - Principal Investigator:
      
      Konstantin Dragnev
- New Jersey
  - Paramus, New Jersey, United States, 07652
    - Recruiting
    - The Valley Hospital, Inc.
    - Principal Investigator:
      
      Eli Kirshner
- New Mexico
  - Albuquerque, New Mexico, United States, 87131
    - Recruiting
    - University of New Mexico Comprehensive Cancer Center
    - Principal Investigator:
      
      Moises Harari Turquie
- New York
  - Brooklyn, New York, United States, 11220
    - Recruiting
    - Maimonides Cancer Center
    - Principal Investigator:
      
      Julie Huang
    - Contact:
      
      Phone Number: 718-765-2600
  - Lake Success, New York, United States, 11042
    - Recruiting
    - Northwell Health/ RJ Zuckerberg Cancer Center
    - Principal Investigator:
      
      Alexander Barbaro
  - Mineola, New York, United States, 11501
    - Recruiting
    - Perlmutter Cancer Center at NYU Langone Hospital - Long Island
    - Principal Investigator:
      
      Joshua Sabari
    - Contact:
      
      Phone Number: 212-731-6363
  - New York, New York, United States, 10065
    - Recruiting
    - Memorial Sloan Kettering Cancer Center
    - Principal Investigator:
      
      Kathryn Arbour
  - New York, New York, United States, 10016
    - Recruiting
    - Laura and Isaac Perlmutter Cancer Center
    - Principal Investigator:
      
      Joshua Sabari
    - Contact:
      
      Phone Number: 212-731-6363
  - New York, New York, United States, 10065
    - Recruiting
    - Manhattan Eye, Ear and Throat Hospital
    - Principal Investigator:
      
      Alexander Barbaro
- North Carolina
  - Chapel Hill, North Carolina, United States, 27599
    - Recruiting
    - University of North Carolina Medical Center
    - Principal Investigator:
      
      Shetal Patel
  - Durham, North Carolina, United States, 27710
    - Recruiting
    - Duke Cancer Institute
    - Principal Investigator:
      
      Jeffrey Clarke
  - Raleigh, North Carolina, United States, 27607
    - Recruiting
    - UNC REX Cancer Center
    - Principal Investigator:
      
      Brendan McNulty
- Ohio
  - Cincinnati, Ohio, United States, 45242
    - Recruiting
    - USO - Oncology Hematology Care
    - Principal Investigator:
      
      Patrick Ward
  - Columbus, Ohio, United States, 43210
    - Recruiting
    - The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T
    - Principal Investigator:
      
      Timothy Burns
    - Contact:
      
      Phone Number: 614-293-3300
- Oregon
  - Eugene, Oregon, United States, 97401
    - Recruiting
    - USO - Oncology Associates of Oregon
    - Contact:
      
      Phone Number: 541-683-5001
    - Principal Investigator:
      
      James E Butrynski
  - Medford, Oregon, United States, 97504
    - Recruiting
    - Asante Rogue Regional Medical Center
    - Contact:
      
      Phone Number: 541-789-5003
    - Principal Investigator:
      
      Alison Savage
  - Portland, Oregon, United States, 97213
    - Recruiting
    - Providence Portland Medical Center
    - Principal Investigator:
      
      Rachel Sanborn
  - Portland, Oregon, United States, 97225
    - Recruiting
    - Providence St. Vincent Medical Center
    - Principal Investigator:
      
      Rachel Sanborn
  - Portland, Oregon, United States, 97227
    - Recruiting
    - Kaiser Permanente Interstate Medical Office Central
    - Principal Investigator:
      
      Sandeep Mashru
    - Contact:
      
      Phone Number: 503-249-3315
- Pennsylvania
  - Horsham, Pennsylvania, United States, 19044
    - Recruiting
    - USO - Alliance Cancer Specialists, PC
    - Principal Investigator:
      
      Joseph Potz
  - Philadelphia, Pennsylvania, United States, 19107
    - Recruiting
    - Thomas Jefferson University, Sidney Kimmel Cancer Center - Clinical Trials Office
    - Principal Investigator:
      
      Sarah Gordon
  - Pittsburgh, Pennsylvania, United States, 15232
    - Recruiting
    - UPMC Hillman Cancer Center
    - Principal Investigator:
      
      Liza Villaruz
- Rhode Island
  - Providence, Rhode Island, United States, 02903
    - Recruiting
    - Lifespan Cancer Institute
    - Principal Investigator:
      
      Christopher Azzoli
- South Carolina
  - Charleston, South Carolina, United States, 29425
    - Recruiting
    - Medical University of South Carolina
    - Principal Investigator:
      
      Mariam Alexander
  - Greenville, South Carolina, United States, 29605
    - Recruiting
    - Prisma Health Cancer Institute
    - Principal Investigator:
      
      Richard O'Neal
  - West Columbia, South Carolina, United States, 29169
    - Recruiting
    - Lexington Medical Center
    - Principal Investigator:
      
      Scott Graupner
    - Contact:
      
      Phone Number: 803-794-7511
- Tennessee
  - Chattanooga, Tennessee, United States, 37404
    - Recruiting
    - Tennessee Oncology Chattanooga
    - Principal Investigator:
      
      Wade Iams
  - Knoxville, Tennessee, United States, 37920
    - Recruiting
    - University of Tennessee Medical Center
    - Contact:
      
      Phone Number: 865-305-8780
    - Principal Investigator:
      
      Ardy Davarifar
  - Memphis, Tennessee, United States, 38120
    - Recruiting
    - Baptist Memorial Hospital-Memphis
    - Principal Investigator:
      
      Osa Ogbeide
  - Nashville, Tennessee, United States, 37203
    - Recruiting
    - Tennessee Oncology
    - Principal Investigator:
      
      Wade Iams
  - Nashville, Tennessee, United States, 37203
    - Recruiting
    - USO - US Oncology Research Network
    - Principal Investigator:
      
      SMO Sarah Cannon Research Inst.
- Texas
  - Austin, Texas, United States, 78745
    - Recruiting
    - USO - Texas Oncology
    - Principal Investigator:
      
      James Uyeki
  - Fort Bliss, Texas, United States, 79918
    - Recruiting
    - William Beaumont Army Medical Center
    - Contact:
      
      Phone Number: 915-203-2268
    - Principal Investigator:
      
      Warren Alexander
  - Houston, Texas, United States, 77030
    - Recruiting
    - Houston Methodist Hospital
    - Contact:
      
      Phone Number: 713-441-9948
    - Principal Investigator:
      
      Jun Zhang
  - Houston, Texas, United States, 77030
    - Recruiting
    - University of Texas MD Anderson Cancer Center
    - Principal Investigator:
      
      Marcelo Vailati Negrao
    - Contact:
      
      Phone Number: 713-792-6363
  - Webster, Texas, United States, 77598
    - Recruiting
    - USO - Texas Oncology
    - Principal Investigator:
      
      Pavel Levin
- Vermont
  - Burlington, Vermont, United States, 05401
    - Recruiting
    - The University of Vermont Medical Center Inc.
    - Principal Investigator:
      
      Rohit Singh
- Virginia
  - Charlottesville, Virginia, United States, 22903
    - Recruiting
    - University of Virginia Health System
    - Principal Investigator:
      
      Ryan Gentzler
    - Contact:
      
      Phone Number: 434-924-4251
  - Fairfax, Virginia, United States, 22031
    - Recruiting
    - USO - Virginia Cancer Specialists
    - Principal Investigator:
      
      Alexander Spira
  - Richmond, Virginia, United States, 23219
    - Recruiting
    - VCU Health Adult Outpatient Pavillion
    - Principal Investigator:
      
      Renato Martins
    - Contact:
      
      Phone Number: 804-828-7999
- Washington
  - Edmonds, Washington, United States, 98026
    - Recruiting
    - Swedish Cancer Institute - Edmonds
    - Principal Investigator:
      
      Siddhartha Devarakonda
  - Kennewick, Washington, United States, 99336
    - Recruiting
    - Kadlec Clinic Hematology and Oncology
    - Principal Investigator:
      
      Ying Zhuo
  - Seattle, Washington, United States, 98108
    - Recruiting
    - VA Puget Sound Health Care System
    - Principal Investigator:
      
      Daniel Wu
  - Seattle, Washington, United States, 98104
    - Recruiting
    - Swedish Medical Center
    - Principal Investigator:
      
      Siddhartha Devarakonda
  - Vancouver, Washington, United States, 98684
    - Recruiting
    - USO - Northwest Cancer Specialists
    - Principal Investigator:
      
      Anthony Van Ho
- Wisconsin
  - Madison, Wisconsin, United States, 53715
    - Recruiting
    - SSM Health Dean Medical Group - South Madison Campus Health Research/Circuit Clinical
    - Principal Investigator:
      
      Lisa Lepeak

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

Adult
Older Adult

Accepts Healthy Volunteers

Description

Inclusion Criteria:

Histologically or cytologically confirmed NSCLC with Stage IIIB-IIIC or Stage IV disease, not suitable for curative intent radical surgery or radiation therapy.
Part B and Safety Lead-In Part B: the histology of the tumor must be predominantly non-squamous (in line with pemetrexed label).
Must have disease with evidence of KRAS G12C mutation.
Must have known programmed death-ligand 1 (PD-L1) expression
- Part A: Greater than or equal to (≥)50 percent (%).
- Part B: 0% to 100%.
- Part C: <50%.
Must have measurable disease per RECIST v1.1.
Must have an ECOG performance status of 0 or 1.
Estimated life expectancy ≥12 weeks.
Ability to swallow capsules.
Must have adequate laboratory parameters.
Contraceptive use should be consistent with local regulations for those participating in clinical studies.
Women of childbearing potential must
- Have a negative pregnancy test.
- Not be breastfeeding during treatment

Exclusion Criteria:

Have a documented additional validated targetable oncogenic driver mutation or alteration in genes such as epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), BRAF (V600E), human epidermal growth factor receptor 2 (HER2), MET (exon 14), ROS1, rearranged during transfection (RET), or neurotrophic tyrosine receptor kinase (NTRK)1/2/3.
Have had any of the following prior to randomization:
-- Prior systemic therapy (chemotherapy, immunotherapy, targeted therapy, or biological therapy) for advanced or metastatic NSCLC.
--- 1 cycle of standard-of-care treatment prior to study enrollment will be allowed for cases where immediate treatment is clinically indicated:
Have known active central nervous system metastases and/or carcinomatous meningitis.

Exclusion Criteria for Participants receiving Pemetrexed and Platinum (Part B and Safety Lead-In Part B)

Have predominantly squamous cell histology for NSCLC
Only for participants with mild to moderate renal insufficiency: Unable to avoid aspirin, ibuprofen, or other nonsteroidal anti-inflammatory drugs (NSAIDs) two days before (5 days for long acting NSAIDs), day of, and two days after administration of pemetrexed
Is unable or unwilling to take folic acid or vitamin B12 supplementation.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Double

Number of Arms

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Dose Optimization: LY3537982 Dose Level 1 plus Pembrolizumab LY3537982 Dose level 1 administered orally in combination with pembrolizumab administered intravenously (IV) in 21-day cycles. Participants may continue to receive treatment until discontinuation criteria are met.	Drug: LY3537982 Administered orally. Other Names: Olomorasib Drug: Pembrolizumab Administered IV.
Experimental: Dose Optimization: LY3537982 Dose Level 2 plus Pembrolizumab LY3537982 Dose level 2 administered orally in combination with pembrolizumab administered IV in 21-day cycles. Participants may continue to receive treatment until discontinuation criteria are met.	Drug: LY3537982 Administered orally. Other Names: Olomorasib Drug: Pembrolizumab Administered IV.
Experimental: Safety Lead In: LY3537982 plus Pembrolizumab, Pemetrexed and Platinum LY3537982 administered orally in combination with pembrolizumab, pemetrexed, and platinum (cisplatin or carboplatin) administered IV in 21-day cycles. Participants may continue to receive treatment until discontinuation criteria are met.	Drug: LY3537982 Administered orally. Other Names: Olomorasib Drug: Pembrolizumab Administered IV. Drug: Cisplatin Administered IV. Drug: Carboplatin Administered IV. Drug: Pemetrexed Administered IV.
Experimental: Part A: LY3537982 plus Pembrolizumab LY3537982 administered orally in combination with pembrolizumab administered IV in 21-day cycles. Participants may continue to receive treatment until discontinuation criteria are met.	Drug: LY3537982 Administered orally. Other Names: Olomorasib Drug: Pembrolizumab Administered IV.
Placebo Comparator: Part A: Placebo plus Pembrolizumab Placebo administered orally in combination with pembrolizumab administered IV in 21-day cycles. Participants may continue to receive treatment until discontinuation criteria are met.	Drug: Placebo Administered orally. Drug: Pembrolizumab Administered IV.
Experimental: Part B: LY3537982 plus Pembrolizumab, Pemetrexed, and Platinum LY3537982 administered orally in combination with pembrolizumab, pemetrexed, and platinum (cisplatin or carboplatin) administered IV in 21-day cycles. Participants may continue to receive treatment until discontinuation criteria are met.	Drug: LY3537982 Administered orally. Other Names: Olomorasib Drug: Pembrolizumab Administered IV. Drug: Cisplatin Administered IV. Drug: Carboplatin Administered IV. Drug: Pemetrexed Administered IV.
Placebo Comparator: Part B: Placebo plus Pembrolizumab, Pemetrexed, and Platinum Placebo administered orally in combination with pembrolizumab, pemetrexed, and platinum (cisplatin or carboplatin) administered IV in 21-day cycles. Participants may continue to receive treatment until discontinuation criteria are met.	Drug: Placebo Administered orally. Drug: Pembrolizumab Administered IV. Drug: Cisplatin Administered IV. Drug: Carboplatin Administered IV. Drug: Pemetrexed Administered IV.
Experimental: Part C: LY3537982 plus Pembrolizumab LY3537982 administered orally in combination with pembrolizumab administered IV in 21-day cycles. Participants may continue to receive treatment until discontinuation criteria are met.	Drug: LY3537982 Administered orally. Other Names: Olomorasib Drug: Pembrolizumab Administered IV.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Dose Optimization and Safety Lead-In Part B: Number of Participants with a Treatment Emergent Adverse Event(s) (TEAE) Time Frame: Randomization to first documented progression of disease or death from any cause. (Estimated as approximately 1 year)	Dose Optimization and Safety Lead-In Part B: Number of Participants with a TEAE	Randomization to first documented progression of disease or death from any cause. (Estimated as approximately 1 year)
Part A and Part B: Progression-Free Survival (PFS) Time Frame: Randomization to first documented progression of disease or death from any cause. (Estimated as approximately 1 year)	PFS per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 by blinded independent central review (BICR)	Randomization to first documented progression of disease or death from any cause. (Estimated as approximately 1 year)

Secondary Outcome Measures

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Eli Lilly and Company

Collaborators

Loxo Oncology, Inc.

Investigators

Study Director: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST), Eli Lilly and Company

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Peters S, Hochmair M, Arbour KC, Rodriguez LP, Reck M, Leal T, R Lindsay C, Shun L, William WN, Spira AI, Sabari JK, Henning Gronberg B, Nishio M, Burns TF, Girard N, Capuzzo F, Merced A, Fasnacht N, Visseren-Grul C, Negrao MV. SUNRAY-01 trial protocol: an innovative study design of olomorasib and pembrolizumab with or without chemotherapy in KRAS G12C NSCLC. Future Oncol. 2026 Apr;22(9):1073-1082. doi: 10.1080/14796694.2026.2651961. Epub 2026 Apr 6.

Helpful Links

A Study of LY3537982 Plus Immunotherapy With or Without Chemotherapy in Participants With Non-Small Cell Lung Cancer (NSCLC) With a Change in a Gene Called KRAS G12C (SUNRAY-01)

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 21, 2023

Primary Completion (Estimated)

November 1, 2027

Study Completion (Estimated)

January 1, 2031

Study Registration Dates

First Submitted

November 1, 2023

First Submitted That Met QC Criteria

November 1, 2023

First Posted (Actual)

November 7, 2023

Study Record Updates

Last Update Posted (Actual)

May 19, 2026

Last Update Submitted That Met QC Criteria

May 18, 2026

Last Verified

May 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

18612
J3M-MC-JZQB (Other Identifier: Eli Lilly and Company)
U1111-1288-0565 (Other Identifier: Universal Trial Number)
2023-503412-33-00 (Other Identifier: EU Trial Number)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

Anonymized individual patient level data will be provided in a secure access environment upon approval of a research proposal and a signed data sharing agreement.

IPD Sharing Time Frame

Data are available 6 months after the primary publication and approval of the indication studied in the US and EU, whichever is later. Data will be indefinitely available for requesting.

IPD Sharing Access Criteria

A research proposal must be approved by an independent review panel and researchers must sign a data sharing agreement.

IPD Sharing Supporting Information Type

STUDY_PROTOCOL
SAP
CSR

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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Outcome Measure	Measure Description	Time Frame
Part A and Part B: Overall Survival (OS) Time Frame: Randomization to date of death from any cause. (Estimated as up to 3 years)	Part A and Part B: OS	Randomization to date of death from any cause. (Estimated as up to 3 years)
Part A and Part B: PFS2 Time Frame: Randomization to disease progression on next line of treatment or death from any cause (Estimated as approximately 1 year	Part A and Part B: PFS2 by Investigator	Randomization to disease progression on next line of treatment or death from any cause (Estimated as approximately 1 year
Part A and Part B: Time to Worsening of NSCLC-related Symptoms as Measured by NSCLC Symptom Assessment Questionnaire (NSCLC-SAQ) Time Frame: Randomization through end of treatment (Estimated as approximately 1 year)	NSCLC symptoms will be assessed using the 7-item NSCLC-SAQ. The NSCLC-SAQ measures overall symptom severity of NSCLC, including cough, pain, dyspnea, fatigue, and poor appetite. Response options range from 0) "Not at all" to 4) "Always" or from 0) "Never" to 4) "Always." The total score ranges from 0-20. Higher scores represent worse symptoms.	Randomization through end of treatment (Estimated as approximately 1 year)
Part A and Part B: Proportion of Time with High Side-Effect Burden, as Measured by Functional Assessment of Cancer Therapy - General Item 5 (FACT-GP5) Time Frame: Randomization through end of treatment (Estimated as approximately 1 year)	FACT-GP5 is a single-item, patient-reported instrument for assessing overall treatment side-effect burden. Response options range from 0) "Not at all" to 4) "Very much." Higher scores represent higher symptom burden.	Randomization through end of treatment (Estimated as approximately 1 year)
Part A and Part B: Change from Baseline in Overall Health-related Quality of Life, as Measured by the EORTC QLQ-C30 Global Health Status/Quality of Life Subscale Time Frame: Randomization through end of treatment (Estimated as approximately 1 year)	The EORTC QLQ-C30 is a 30-question patient-reported instrument used to assess multidimensional HRQoL in cancer patients. Overall HRQoL is measured by the EORTC QLQ-30 Global Health Status/Quality of Life Subscale (two items). Response options range from 1) "very poor" to 7) "excellent." Scores are linearly transformed to the range 0 - 100. Higher scores represent better overall HRQoL.	Randomization through end of treatment (Estimated as approximately 1 year)
Part A and Part B: Changes in NSCLC-related symptoms as measured by NSCLC-SAQ Time Frame: Randomization through end of treatment (Estimated as approximately 1 year)]	NSCLC-related symptoms are assessed by the NSCLC-SAQ total score, which is computed as the sum of the 5 domains (7 questions) and ranges from 0 to 20. The total score will be calculated if all 7 questions are completed. Higher scores indicate more severe symptomatology.	Randomization through end of treatment (Estimated as approximately 1 year)]
Part A and Part B: Changes in physical function, as measured by the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (EORTC QLQ-C30) Physical Functioning subscale and IL19 Time Frame: Randomization through end of treatment (Estimated as approximately 1 year)	Physical function is assessed by EORTC-QLQ-C30 Physical Functioning scale or IL19. The physical function score is calculated by generating the raw score: (Q1+Q2+Q3+Q4+Q5)/5; and then generating the transformed score: (1-((raw score-1)/3)) x 100. The score ranges from 0 to 100. Higher scores indicate better physical function.	Randomization through end of treatment (Estimated as approximately 1 year)
Part A and Part B: Time to Deterioration in Physical Function, as Measured by the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (EORTC QLQ-C30) Physical Functioning Subscale and IL19 Time Frame: Randomization through end of treatment (Estimated as approximately 1 year)	The EORTC QLQ-C30 is a 30-question patient-reported instrument used to assess multidimensional health-related quality of life (HRQoL) in cancer patients. Physical functioning is measured by the EORTC-QLQ-30 Physical Function Scale (five items). Response options range from 1) "Not at all" to 4) "Very much." The sum score is linearly transformed to the range 0 - 100. Higher scores represent better physical function.	Randomization through end of treatment (Estimated as approximately 1 year)
Part A and Part B: PFS Time Frame: Randomization to first documented progression of disease or death from any cause. (Estimated as approximately 1 year)	PFS per RECIST v1.1 by investigator	Randomization to first documented progression of disease or death from any cause. (Estimated as approximately 1 year)
Part A and Part B: Overall Response Rate (ORR): Percentage of Participants who Achieve a Best Overall Response (BOR) of Complete Response (CR) or Partial Response (PR) Time Frame: Randomization to disease progression or death. (Estimated as approximately 1 year)	ORR per RECIST v1.1 by BICR and Investigator	Randomization to disease progression or death. (Estimated as approximately 1 year)
Part A and Part B: Duration of Response (DOR) Time Frame: Date of first evidence of CR or PR to date of disease progression or death from any cause. (Estimated as approximately 1 year)	DOR per RECIST v1.1 by BICR and Investigator	Date of first evidence of CR or PR to date of disease progression or death from any cause. (Estimated as approximately 1 year)
Part A and Part B: Disease Control Rate (DCR): Percentage of Participants who Achieve a BOR of CR, PR, or Stable Disease (SD) Time Frame: Randomization to disease progression or death from any cause. (Estimated as approximately 1 year)	DCR per RECIST v1.1 by BICR and Investigator	Randomization to disease progression or death from any cause. (Estimated as approximately 1 year)
Part A and Part B: Time to Response (TTR) Time Frame: Time from randomization until the date that measurement criteria for CR or PR (whichever is first recorded) are first met (Estimated as approximately 1 year)	TTR per RECIST v1.1 by BICR and Investigator	Time from randomization until the date that measurement criteria for CR or PR (whichever is first recorded) are first met (Estimated as approximately 1 year)
Part A and Part B: Intracranial Overall Response Rate (ORR) Time Frame: Randomization to intracranial disease progression or death. (Estimated as approximately 1 year)	Intracranial ORR per Modified RECIST (mRECIST) by BICR	Randomization to intracranial disease progression or death. (Estimated as approximately 1 year)
Part A and Part B: Intracranial Duration of Response (DoR) Time Frame: Date of first evidence of CR or PR to date of intracranial disease progression or death from any cause. (Estimated as approximately 1 year)	Intracranial DoR per mRECIST by BICR	Date of first evidence of CR or PR to date of intracranial disease progression or death from any cause. (Estimated as approximately 1 year)

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer (SUNRAY-01)

Study Overview

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Intervention / Treatment

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Contacts and Locations

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Accepts Healthy Volunteers

Description

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Design Details

Number of Arms

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Secondary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Collaborators and Investigators

Sponsor

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First Submitted That Met QC Criteria

First Posted (Actual)

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Last Update Submitted That Met QC Criteria

Last Verified

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