Psychiatric Disorder in Dysnergic Defecation

June 30, 2026 updated by: Dina Medhat Hussein, Assiut University

Psychiatric Assessment of Patients With Dyssynergic Defecation and Its Impact on Their Quality of Life

Case control observational study conducted on DD patient and healthy control group.

  1. evaluate psychiatric disorders among patients with dyssynergic defecation
  2. evaluate the effect of delayed diagnosis of dysnergic defecation on the quality of the life

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Functional constipation is a functional bowel disorder that presents as persistently difficult, infrequent, or seemingly incomplete defecation.

Subjective and objective definitions of constipation include:

(1) straining, hard stools (hard, inspissated stool), unproductive calls ("want to but cannot"), infrequent stools, or incomplete evacuation. (2) <3 bowel movements per week, daily stool weight <35 g/day, or straining >25% of the time Dyssynergia defecation is common and affects up to one half of patients with chronic constipation. This acquired behavioral problem is due to the inability to coordinate the abdominal and pelvic floor muscles to evacuate stool The etiology of dyssynergic defecation is unclear however it was found that the problem began during childhood in 31% of patients, and after a particular event, such as pregnancy, trauma, or back injury in 29% of patients, and there was no cause in 40% of patients.

The first step in making a diagnosis of dyssynergic defecation is to exclude an underlying metabolic or pathologic disorder .A detailed history, prospective stool diaries, and a careful digital rectal examination will not only identify the nature of bowel dysfunction, but also raise the index of suspicion for this evacuation disorder. Anorectal physiology tests and balloon expulsion test are essential for a diagnosis. Newer techniques such as high-resolution manometry and magnetic resonance defecography can provide mechanistic insights.

. anorectal dyssynergia impact quality of life and cause psychiatric problems such as of anxiety, depression, obsessive compulsiveness, psychoticism, and somatization.

So, the investigators aim to evaluate psychiatric disorders among those patients and impact of delayed diagnosis on their quality of life.

Study Type

Observational

Enrollment (Actual)

148

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Asyut, Egypt
        • Git center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Disease group suffer from chronic conistipation and diagnosed dyssynergic defecation

Description

Inclusion Criteria:

  • patients diagnosed as dyssynergia with anorectal manometric study

Exclusion Criteria:

  • patient with diabetes mellitus ,hypertension ,chronic kidney disease ,and chronic liver disease patients
  • patient with neurological disease
  • patient with thyroid disease
  • patient with past history of psychiatric disorders
  • patients with past or current medications or substance induced psychiatric disorders

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Dysnergic defecation disease group
Healthy control population
Other: No intervention
No intervention,only observation case control study

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
1-Assess psychiatric disorders among patients with dyssynergic defecation
Time Frame: through study completion, an average of 1 year
Review the different types of psychiatric disorders in patients have diagnosed DD using SCID-5 ,anxiety and depression Hamilton score (from 0-4,zero refer to no symptoms ,4 refer to sever symptoms ), the summation of them show the type and severity of the condition
through study completion, an average of 1 year

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
The impact of dyssynergia defecation on the quality of the life
Time Frame: Through study completion, an average of 1 year
By using survey contain 36 short question about the quality of the life of the patient with dyssynergia defecation and compare the answer with those of normal people
Through study completion, an average of 1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assiut University

Investigators

  • Study Director: Bahaa osman, teacher, Assiut University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

November 1, 2023

Primary Completion (Actual)

September 1, 2025

Study Completion (Actual)

January 31, 2026

Study Registration Dates

First Submitted

August 21, 2023

First Submitted That Met QC Criteria

November 9, 2023

First Posted (Actual)

November 13, 2023

Study Record Updates

Last Update Posted (Actual)

July 1, 2026

Last Update Submitted That Met QC Criteria

June 30, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • psycosis&dyssynergic defecatio

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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