Periapical Lesions and Immediate Implants

July 24, 2024 updated by: Mehmet Ali Altay, Akdeniz University

Immediate Implant Placement in Sites With Chronic Periapical Lesions

The aim of this case-control study is to evaluate the success and survival rates of dental implants immediately placed into extraction sites in the presence of periapical pathology.

The main questions it aims to answer are:

What were the survival and success rates of implants immediately placed into extraction sockets of teeth with chronic periodical lesions.

A retrospective analysis was performed based on the evaluation of certain clinical and radiographic parameters 12 months after prosthetic function of these implants.

Study Overview

Status

Completed

Conditions

Detailed Description

In 25 patients (13 men, 12 women), certain clinical and radiological parameters were retrospectively evaluated with particular interest in survival and success rates of the implants (total of 30 implants, 21 in the maxilla, 9 in the mandible) placed immediately to extraction sites of teeth with chronic periapical lesions. These parameters included mobility and the presence or absence of chronic pain, probing depth, gingival index, radiographic measurements of crestal bone loss on mesial and distal aspects of the implants.

Study Type

Observational

Enrollment (Actual)

25

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
      • Antalya, Turkey, 07070
        • Akdeniz University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

The present study included patients, who underwent immediate implant placement following extraction of a tooth with periapical pathology.

Description

Inclusion Criteria:

  • To have 1 or more teeth with a chronic periapical lesion that requiring extraction.
  • The chronic periapical lesion should be determined as an asymptomatic periapical radiolucency with a diameter ranging between 4 and 8 mm.
  • The patients undergoing tooth extraction must have been treated with an immediate implant placement procedure.
  • At the time of extraction and implant placement, the neighboring teeth must have had healthy periodontal and periapical status.

Exclusion Criteria:

  • Age younger than 18 years
  • Any systemic disease or medication that might compromise osseointegration, bone or soft tissue healing
  • Smoking
  • Purulent exudate during the extraction
  • Severe deficiency of soft and/or hard tissue in implant region
  • Pregnancy
  • Lactation
  • History of chemotherapy or radiotherapy
  • Severe parafunctional habits

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Survival of the implants
Time Frame: Immediately after the implant placement and after 12 months of prosthesis function.
Pain on palpation, percussion, or function (Yes/No) Implant mobility (Yes/No) Radiographic crestal bone loss (<4.0 mm) Absence of pain and mobility and crestal bone loss up to 4 mm were regarded as survive.
Immediately after the implant placement and after 12 months of prosthesis function.
Success of the implants
Time Frame: Immediately after the implant placement and after 12 months of prosthesis function.
Pain on palpation, percussion, or function (Yes/No) Implant mobility (Yes/No) Radiographic crestal bone loss (<2mm) Gingival index score (1-2-3) Probing depth (mm) Absence of pain and mobility, crestal bone loss <2mm, GI score less than 2, probing depth <5mm were regarded as success.
Immediately after the implant placement and after 12 months of prosthesis function.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Akdeniz University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2016

Primary Completion (Actual)

January 1, 2018

Study Completion (Actual)

December 1, 2023

Study Registration Dates

First Submitted

July 17, 2024

First Submitted That Met QC Criteria

July 24, 2024

First Posted (Actual)

July 25, 2024

Study Record Updates

Last Update Posted (Actual)

July 25, 2024

Last Update Submitted That Met QC Criteria

July 24, 2024

Last Verified

July 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 20022019/188

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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