Impact of COVID-19 on Pregnancy Outcomes: a Systematic Review (COVID-PREG)

November 5, 2024 updated by: Hamidreza Kouhpayeh, Zahedan University of Medical Sciences

A Systematic Review of COVID-19's Impact on Pregnancy Outcomes

This systematic review aims to evaluate the impact of COVID-19 on pregnancy outcomes. It synthesizes data from various studies to provide insights into the effects of the virus on maternal and fetal health. The review focuses on key outcomes such as preterm birth, maternal complications, and neonatal health, utilizing comprehensive literature from peer-reviewed journals. By analyzing existing studies, we aim to identify trends and gaps in research regarding COVID-19 and pregnancy. This review is intended to inform healthcare providers and pregnant individuals about potential risks and considerations during the pandemic.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

1

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Iran, Islamic Republic of
    • Sistan and Baluchestan
      • Zahedan, Sistan and Baluchestan, Iran, Islamic Republic of
        • Zahedan University of Medical Sciences

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

The study population consists of pregnant individuals diagnosed with COVID-19 as documented in various peer-reviewed studies. The review examines the impact of COVID-19 on pregnancy outcomes, including maternal health, delivery outcomes, and neonatal complications.

Description

Inclusion Criteria:

  • Pregnant individuals diagnosed with COVID-19.
  • Studies reporting pregnancy outcomes related to COVID-19 published between January 2020 and the present.
  • Articles that include quantitative data on maternal and fetal outcomes.

Exclusion Criteria:

  • Studies that do not report on COVID-19-related pregnancy outcomes.
  • Non-peer-reviewed articles or grey literature.
  • Research focusing on non-pregnant populations.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Impact of COVID-19 on Maternal and Neonatal Outcomes
Time Frame: The review encompasses studies published from January 2020 to the present, with a focus on maternal and neonatal outcomes reported within the specified time frame.
This primary outcome measure evaluates the various maternal and neonatal outcomes associated with COVID-19 infection during pregnancy. Key metrics include rates of maternal morbidity, neonatal morbidity, preterm birth, low birth weight, and any documented complications during pregnancy, labor, and delivery. The systematic review aims to synthesize data from available studies to provide a comprehensive understanding of these outcomes and their implications for clinical practice.
The review encompasses studies published from January 2020 to the present, with a focus on maternal and neonatal outcomes reported within the specified time frame.

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Effects of COVID-19 on Pregnancy-Related Complications
Time Frame: The review includes data from studies published between January 2020 and the present, focusing on complications reported throughout the pregnancy and at delivery.
This secondary outcome measure assesses the frequency and types of pregnancy-related complications associated with COVID-19. This includes conditions such as gestational hypertension, gestational diabetes, placental abruption, and other adverse effects that may arise during the pregnancy period. The review aims to analyze the incidence of these complications in pregnant individuals diagnosed with COVID-19 compared to non-infected counterparts, providing insights into how the virus may impact overall pregnancy health.
The review includes data from studies published between January 2020 and the present, focusing on complications reported throughout the pregnancy and at delivery.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Zahedan University of Medical Sciences

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 3, 2024

Primary Completion (Actual)

August 15, 2024

Study Completion (Actual)

August 25, 2024

Study Registration Dates

First Submitted

November 5, 2024

First Submitted That Met QC Criteria

November 5, 2024

First Posted (Actual)

November 6, 2024

Study Record Updates

Last Update Posted (Actual)

November 6, 2024

Last Update Submitted That Met QC Criteria

November 5, 2024

Last Verified

November 1, 2024

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • COVID-PREG-2024-001

Drug and device information, study documents

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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