Do Emotions Affect Mechanical Pain Thresholds in Individuals with Chronic Pain?
February 17, 2025 updated by: Helena Gunnarsson, Linnaeus University
Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables in Individuals with Chronic Pain
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds in individuals with chronic pain.
Study Overview
Status
Not yet recruiting
Conditions
Intervention / Treatment
Detailed Description
Participants will be randomized into 4 different groups watching different short video-clips (2.20 min).
The negative emotions group will watch an uncomfortable short video containing violence and blood, the positive emotions group will watch a video containing a stand-up comedy show, the neutral emotions group will watch a video about how to paint a house, and the control group will just wait for 2.20 min, without any instructions about what to think about.
Pressure pain thresholds will be measured with an algometer before and after the video-clips.
Study Type
Interventional
Enrollment (Estimated)
152
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Helena Gunnarsson, Dr
- Phone Number: +46708432509
- Email: helena.gunnarsson@lnu.se
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Description
Inclusion criteria
- Above 18 years of age
- Fluent in Swedish
- Persistent chronic pain with duration > 6 months Exclusion criteria
- Known neurological disease
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Negative emotional condition
The participant will watch a short video-clip with negative emotional content.
|
Negative emotional intervention
Positive emotional intervention
|
|
Experimental: Positive emotional condition
The participant will watch a short video-clip with positive emotional content.
|
Negative emotional intervention
Positive emotional intervention
|
|
Sham Comparator: Neutral emotional condition
The participant will watch a short video-clip with neutral emotional content.
|
Negative emotional intervention
Positive emotional intervention
|
|
Sham Comparator: No emotional condition
The participant will wait for 2.30 minutes without any instructions about how to engage their thoughts.
|
Negative emotional intervention
Positive emotional intervention
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Pressure pain thresholds will be measured in kPa
Time Frame: The measurement takes place at the intervention session. First a baseline measurement is conducted, then comes the intervention and then the intervention measurement takes place.
|
Pressure pain thresholds will be measured in kPa using a handheld algometer (Somedic AB).
|
The measurement takes place at the intervention session. First a baseline measurement is conducted, then comes the intervention and then the intervention measurement takes place.
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Estimated)
January 1, 2026
Primary Completion (Estimated)
June 1, 2027
Study Completion (Estimated)
December 31, 2027
Study Registration Dates
First Submitted
February 12, 2025
First Submitted That Met QC Criteria
February 17, 2025
First Posted (Actual)
March 25, 2025
Study Record Updates
Last Update Posted (Actual)
March 25, 2025
Last Update Submitted That Met QC Criteria
February 17, 2025
Last Verified
February 1, 2025
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- Dnr 2024-07781-01
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
UNDECIDED
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
product manufactured in and exported from the U.S.
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.