Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib (STOP-LTR)

May 29, 2026 updated by: Incyte Corporation

A Phase 3b, Multicenter, Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

Rollover study for participants from predetermined, Incyte-sponsored parent clinical trials of povorcitinib.

Study Overview

Status

Recruiting

Conditions

Hidradenitis Suppurativa (HS)

Intervention / Treatment

Drug: povorcitinib

Study Type

Interventional

Enrollment (Estimated)

600

Phase

Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Name: Incyte Corporation Call Center (US)
Phone Number: 1.855.463.3463
Email: medinfo@incyte.com

Study Contact Backup

Name: Incyte Corporation Call Center (ex-US)
Phone Number: +800 00027423
Email: eumedinfo@incyte.com

Study Locations

Argentina
- - Buenos Aires, Argentina, C1425BEN
    - Not yet recruiting
    - Investigative Site AR006
  - Buenos Aires, Argentina, 01018
    - Not yet recruiting
    - Investigative Site AR005
  - Buenos Aires, Argentina, C1060ABN
    - Not yet recruiting
    - Investigative Site AR002
  - Mar del Plata, Argentina, B7600FYK
    - Not yet recruiting
    - Investigative Site AR004
  - Rosario, Argentina, S2000
    - Not yet recruiting
    - Investigative Site AR003
  - San Miguel de Tucumán, Argentina, T4000AXL
    - Not yet recruiting
    - Investigative Site AR001
Australia
- - Fremantle, Australia, 06160
    - Not yet recruiting
    - Investigative Site AU008
  - Westmead, Australia, 02145
    - Not yet recruiting
    - Investigative Site AU009
- New South Wales
  - Charleston, New South Wales, Australia, 02290
    - Recruiting
    - Investigative Site AU001
  - Kogarah, New South Wales, Australia, 02217
    - Recruiting
    - Investigative Site AU003
  - Liverpool, New South Wales, Australia, 02170
    - Recruiting
    - Investigative Site AU005
  - Sydney, New South Wales, Australia, 02010
    - Not yet recruiting
    - Investigative Site AU010
- Queensland
  - Wolloongabba, Queensland, Australia, 04102
    - Not yet recruiting
    - Investigative Site AU007
- Victoria
  - Melbourne, Victoria, Australia, 03002
    - Recruiting
    - Investigative Site AU002
  - Melbourne, Victoria, Australia, 03004
    - Completed
    - Investigative Site AU011
Austria
- - Graz, Austria, 08036
    - Recruiting
    - Investigative Site AT002
  - Innsbruck, Austria, 06020
    - Recruiting
    - Investigative Site AT004
  - Vienna, Austria, 01130
    - Not yet recruiting
    - Investigative Site AT003
Belgium
- - Bruges, Belgium, 08000
    - Not yet recruiting
    - Investigative Site BE007
  - Brussels, Belgium, 01070
    - Not yet recruiting
    - Investigative Site BE002
  - Ghent, Belgium, 09000
    - Recruiting
    - Investigative Site BE001
  - Liège, Belgium, 04000
    - Not yet recruiting
    - Investigative Site BE003
  - Loverval, Belgium, 06280
    - Not yet recruiting
    - Investigative Site BE006
  - Woluwe-Saint-Lambert, Belgium, 01200
    - Not yet recruiting
    - Investigative Site BE005
Bulgaria
- - Dupnitsa, Bulgaria, 02600
    - Not yet recruiting
    - Investigative Site BG008
  - Lovech, Bulgaria, 05500
    - Recruiting
    - Investigative Site BG010
  - Pleven, Bulgaria, 05800
    - Recruiting
    - Investigative Site BG012
  - Plovdiv, Bulgaria, 04002
    - Not yet recruiting
    - Investigative Site BG013
  - Sevlievo, Bulgaria, 05400
    - Recruiting
    - Investigative Site BG007
  - Sofia, Bulgaria, 01202
    - Not yet recruiting
    - Investigative Site BG009
  - Sofia, Bulgaria, 01431
    - Not yet recruiting
    - Investigative Site BG006
  - Sofia, Bulgaria, 01431
    - Not yet recruiting
    - Investigative Site BG011
  - Sofia, Bulgaria, 01528
    - Not yet recruiting
    - Investigative Site BG014
  - Sofia, Bulgaria, 01510
    - Recruiting
    - Investigative Site BG001
  - Sofia, Bulgaria, 01407
    - Recruiting
    - Investigative Site BG002
  - Sofia, Bulgaria, 01463
    - Recruiting
    - Investigative Site BG003
  - Stara Zagora, Bulgaria, 06003
    - Not yet recruiting
    - Investigative Site BG004
Canada
- Alberta
  - Calgary, Alberta, Canada, T2J 7E1
    - Not yet recruiting
    - Investigative Site CA023
  - Calgary, Alberta, Canada, T3E 0B2
    - Recruiting
    - Investigative Site CA008
  - Edmonton, Alberta, Canada, T6W 4V4
    - Not yet recruiting
    - Investigative Site CA028
  - Edmonton, Alberta, Canada, T6X 0N9
    - Not yet recruiting
    - Investigative Site CA027
  - Edmonton, Alberta, Canada, T6G 1C3
    - Recruiting
    - Investigative Site CA005
  - Sherwood Park, Alberta, Canada, T8H 0P1
    - Not yet recruiting
    - Investigative Site CA031
- British Columbia
  - Surrey, British Columbia, Canada, V3V 0C6
    - Not yet recruiting
    - Investigative Site CA013
  - Vancouver, British Columbia, Canada, V5Z 4E8
    - Not yet recruiting
    - Investigative Site CA024
- Manitoba
  - Winnipeg, Manitoba, Canada, R3M 3Z4
    - Recruiting
    - Investigative Site CA003
- Ontario
  - Barrie, Ontario, Canada, L4M 7G1
    - Recruiting
    - Investigative Site CA004
  - Cobourg, Ontario, Canada, K9A 0Z4
    - Recruiting
    - Investigative Site CA030
  - London, Ontario, Canada, N6A 2C2
    - Not yet recruiting
    - Investigative Site CA025
  - London, Ontario, Canada, N6H 5L5
    - Recruiting
    - Investigative Site CA002
  - Markham, Ontario, Canada, L3P 1X3
    - Not yet recruiting
    - Investigative Site CA022
  - Mississauga, Ontario, Canada, L4Y 4C5
    - Recruiting
    - Investigative Site CA016
  - Peterborough, Ontario, Canada, K9J 5K2
    - Recruiting
    - Investigative Site CA001
  - Richmond Hill, Ontario, Canada, L4C 9M7
    - Not yet recruiting
    - Investigative Site CA010
  - Toronto, Ontario, Canada, M2N 3A6
    - Not yet recruiting
    - Investigative Site CA017
  - Toronto, Ontario, Canada, M3H 5Y8
    - Recruiting
    - Investigative Site CA018
  - Toronto, Ontario, Canada, M4W 2N4
    - Recruiting
    - Investigative Site CA021
  - Waterloo, Ontario, Canada, N2J 1C4
    - Recruiting
    - Investigative Site CA019
- Quebec
  - Québec, Quebec, Canada, G1W 4R4
    - Recruiting
    - Investigative Site CA026
  - Québec, Quebec, Canada, G1V4X7
    - Recruiting
    - Investigative Site CA020
  - Saint-Jérôme, Quebec, Canada, J7Z 7E2
    - Not yet recruiting
    - Investigative Site CA009
  - Verdun, Quebec, Canada, H4G 3E7
    - Not yet recruiting
    - Investigative Site CA029
- Saskatchewan
  - Saskatoon, Saskatchewan, Canada, S7K 2C1
    - Recruiting
    - Investigative Site CA015
Chile
- - LAS Condes Santiago, Chile, 7580206
    - Not yet recruiting
    - Investigative Site CL002
  - Santiago, Chile, 8420383
    - Not yet recruiting
    - Investigative Site CL003
  - Valdivia, Chile, 5090000
    - Not yet recruiting
    - Investigative Site CL001
Czechia
- - Ostrava-poruba, Czechia, 708 52
    - Recruiting
    - Investigative Site CZ002
  - Prague, Czechia, 150 06
    - Not yet recruiting
    - Investigative Site CZ001
  - Prague, Czechia, 100 00
    - Not yet recruiting
    - Investigative Site CZ004
  - Prague, Czechia, 110 00
    - Not yet recruiting
    - Investigative Site CZ003
France
- - Antony, France, 92160
    - Recruiting
    - Investigative Site FR014
  - Bordeaux, France, 33000
    - Recruiting
    - Investigative Site FR006
  - Brest, France, 29609
    - Recruiting
    - Investigative Site FR004
  - Créteil, France, 94000
    - Not yet recruiting
    - Investigative Site FR015
  - Lyon, France, 69003
    - Recruiting
    - Investigative Site FR009
  - Marseille, France, 13005
    - Recruiting
    - Investigative Site FR012
  - Nantes, France, 44093
    - Recruiting
    - Investigative Site FR011
  - Nice, France, 06200
    - Recruiting
    - Investigative Site FR008
  - Paris, France, 75010
    - Recruiting
    - Investigative Site FR010
  - Reims, France, 51100
    - Recruiting
    - Investigative Site FR005
  - Romans-sur-Isère, France, 26102
    - Not yet recruiting
    - Investigative Site FR018
  - Rouen, France, 76031
    - Recruiting
    - Investigative Site FR007
  - Saint-Priest-en-Jarez, France, 42270
    - Recruiting
    - Investigative Site FR003
  - Toulouse, France, 31059
    - Recruiting
    - Investigative Site FR001
Germany
- - Aachen, Germany, 52074
    - Recruiting
    - Investigative Site DE036
  - Bad Bentheim, Germany, 48455
    - Recruiting
    - Investigative Site DE025
  - Berlin, Germany, 10117
    - Recruiting
    - Investigative Site DE005
  - Berlin, Germany, 10247
    - Recruiting
    - Investigative Site DE026
  - Berlin, Germany, 12203
    - Not yet recruiting
    - Investigative Site DE039
  - Bochum, Germany, 44791
    - Not yet recruiting
    - Investigative Site DE006
  - Bonn, Germany, 53105
    - Not yet recruiting
    - Investigative Site DE037
  - Buxtehude, Germany, 21614
    - Recruiting
    - Investigative Site DE024
  - Chemnitz, Germany, 09117
    - Not yet recruiting
    - Investigative Site DE023
  - Darmstadt, Germany, 64283
    - Recruiting
    - Investigative Site DE013
  - Darmstadt, Germany, 64283
    - Recruiting
    - Investigative Site DE019
  - Dortmund, Germany, 44137
    - Not yet recruiting
    - Investigative Site DE027
  - Dresden, Germany, 01307
    - Recruiting
    - Investigative Site DE012
  - Düsseldorf, Germany, 40225
    - Recruiting
    - Investigative Site DE014
  - Erlangen, Germany, 91054
    - Not yet recruiting
    - Investigative Site DE009
  - Frankfurt am Main, Germany, 60590
    - Recruiting
    - Investigative Site DE011
  - Göttingen, Germany, 37075
    - Recruiting
    - Investigative Site DE010
  - Halle, Germany, 06120
    - Not yet recruiting
    - Investigative Site DE032
  - Hamburg, Germany, 20246
    - Recruiting
    - Investigative Site DE001
  - Hanover, Germany, 30159
    - Recruiting
    - Investigative Site DE002
  - Heidelberg, Germany, 69115
    - Recruiting
    - Investigative Site DE017
  - Kiel, Germany, 24105
    - Recruiting
    - Investigative Site DE003
  - Leipzig, Germany, 04103
    - Recruiting
    - Investigative Site DE033
  - Lübeck, Germany, 23538
    - Recruiting
    - Investigative Site DE034
  - Magdeburg, Germany, 39104
    - Not yet recruiting
    - Investigative Site DE029
  - Mainz, Germany, 55128
    - Not yet recruiting
    - Investigative Site DE015
  - Mainz, Germany, 55131
    - Not yet recruiting
    - Investigative Site DE035
  - Marburg, Germany, 35043
    - Not yet recruiting
    - Investigative Site DE038
  - Merzig, Germany, 66663
    - Recruiting
    - Investigative Site DE008
  - München, Germany, 80802
    - Not yet recruiting
    - Investigative Site DE030
  - Oldenburg, Germany, 26133
    - Recruiting
    - Investigative Site DE028
  - Tübingen, Germany, 72076
    - Not yet recruiting
    - Investigative Site DE031
  - Witten, Germany, 58453
    - Recruiting
    - Investigative Site DE018
Greece
- - Athens, Greece, 12462
    - Recruiting
    - Investigative Site GR001
  - Athens, Greece, 16121
    - Recruiting
    - Investigative Site GR002
  - Thessaloniki, Greece, 56429
    - Not yet recruiting
    - Investigative Site GR003
Hungary
- - Debrecen, Hungary, 04032
    - Not yet recruiting
    - Investigative Site HU001
  - Szombathely, Hungary
    - Not yet recruiting
    - Investigative Site HU002
Italy
- - Bari, Italy, 70124
    - Not yet recruiting
    - Investigative Site IT012
  - Brescia, Italy, 25123
    - Not yet recruiting
    - Investigative Site IT009
  - Catania, Italy, 95123
    - Recruiting
    - Investigative Site IT001
  - Chieti, Italy, 66013
    - Not yet recruiting
    - Investigative Site IT007
  - Florence, Italy, 50125
    - Not yet recruiting
    - Investigative Site IT014
  - L’Aquila, Italy, 67100
    - Not yet recruiting
    - Investigative Site IT010
  - Milan, Italy, 20122
    - Not yet recruiting
    - Investigative Site IT005
  - Naples, Italy, 80131
    - Not yet recruiting
    - Investigative Site IT008
  - Perugia, Italy, 06129
    - Not yet recruiting
    - Investigative Site IT013
  - Pisa, Italy, 56126
    - Not yet recruiting
    - Investigative Site IT006
  - Rome, Italy, 00168
    - Recruiting
    - Investigative Site IT002
  - Rozzano, Italy, 20089
    - Recruiting
    - Investigative Site IT003
  - Torrette DI Ancona, Italy, 60020
    - Not yet recruiting
    - Investigative Site IT004
Netherlands
- - Amsterdam, Netherlands, 1105 AZ
    - Not yet recruiting
    - Investigative Site NL005
  - Amsterdam, Netherlands, 1105 AZ
    - Not yet recruiting
    - Investigative Site NL007
  - Bergen op Zoom, Netherlands, 4624 VT
    - Not yet recruiting
    - Investigative Site NL006
  - Groningen, Netherlands, 9713 GZ
    - Recruiting
    - Investigative Site NL003
  - Rotterdam, Netherlands, 3015 GD
    - Recruiting
    - Investigative Site NL001
  - Veldhoven, Netherlands, 5504 DB
    - Not yet recruiting
    - Investigative Site NL004
Poland
- - Cracov, Poland, 30-348
    - Recruiting
    - Investigative Site PL013
  - Gdansk, Poland, 80-280
    - Recruiting
    - Investigative Site PL009
  - Grodzisk Mazowiecki, Poland
    - Recruiting
    - Investigative Site PL029
  - Katowice, Poland, 40-568
    - Recruiting
    - Investigative Site PL011
  - Katowice, Poland, 40-600
    - Recruiting
    - Investigative Site PL025
  - Lodz, Poland, 90-436
    - Recruiting
    - Investigative Site PL021
  - Lodz, Poland, 90-302
    - Recruiting
    - Investigative Site PL036
  - Lublin, Poland, 20-573
    - Recruiting
    - Investigative Site PL002
  - Lublin, Poland, 20-406
    - Recruiting
    - Investigative Site PL031
  - Lublin, Poland, 20-607
    - Not yet recruiting
    - Investigative Site PL045
  - Osielsko, Poland, 86-031
    - Not yet recruiting
    - Investigative Site PL020
  - Ostrowiec Świętokrzyski, Poland, 27-400
    - Recruiting
    - Investigative Site PL006
  - Poznan, Poland, 61731
    - Not yet recruiting
    - Investigative Site PL016
  - Rzeszów, Poland, 35-055
    - Recruiting
    - Investigative Site PL003
  - Skierniewice, Poland, 96-100
    - Not yet recruiting
    - Investigative Site PL043
  - Szczecin, Poland, 70-332
    - Not yet recruiting
    - Investigative Site PL028
  - Tarnów, Poland, 33-100
    - Not yet recruiting
    - Investigative Site PL010
  - Torun, Poland, 87-100
    - Not yet recruiting
    - Investigative Site PL030
  - Warsaw, Poland, 01-142
    - Not yet recruiting
    - Investigative Site PL017
  - Warsaw, Poland, 02-661
    - Not yet recruiting
    - Investigative Site PL012
  - Warsaw, Poland, 02-692
    - Not yet recruiting
    - Investigative Site PL004
  - Warsaw, Poland, 02-953
    - Recruiting
    - Investigative Site PL027
  - Warsaw, Poland, 02-507
    - Recruiting
    - Investigative Site PL007
  - Warsaw, Poland, 00-124
    - Not yet recruiting
    - Investigative Site PL046
  - Warsaw, Poland, 02-625
    - Recruiting
    - Investigative Site PL014
  - Warsaw, Poland, 01-817
    - Recruiting
    - Investigative Site PL026
  - Warsaw, Poland, 03-291
    - Not yet recruiting
    - Investigative Site PL024
  - Wroclaw, Poland, 54144
    - Not yet recruiting
    - Investigative Site PL008
  - Wroclaw, Poland, 50-450
    - Not yet recruiting
    - Investigative Site PL018
  - Wroclaw, Poland, 54144
    - Not yet recruiting
    - Investigative Site PL022
  - Wroclaw, Poland, 50-566
    - Recruiting
    - Investigative Site PL001
  - Wroclaw, Poland, 51-503
    - Recruiting
    - Investigative Site PL005
  - Wroclaw, Poland, 52-416
    - Not yet recruiting
    - Investigative Site PL015
South Korea
- - Ansan-si, South Korea, 15355
    - Recruiting
    - Investigative Site KR006
  - Busan, South Korea, 49241
    - Not yet recruiting
    - Investigative Site KR007
  - Incheon, South Korea, 21431
    - Not yet recruiting
    - Investigative Site KR003
  - Seoul, South Korea, 03080
    - Not yet recruiting
    - Investigative Site KR002
  - Yangsan, South Korea, 50612
    - Recruiting
    - Investigative Site KR001
Spain
- - Alicante, Spain, 03010
    - Not yet recruiting
    - Investigative Site ES025
  - Badalona, Spain, 08916
    - Recruiting
    - Investigative Site ES001
  - Badalona, Spain, 08916
    - Recruiting
    - Investigative Site ES024
  - Barcelona, Spain, 08026
    - Not yet recruiting
    - Investigative Site ES017
  - Barcelona, Spain, 08003
    - Recruiting
    - Investigative Site ES010
  - Córdoba, Spain, 14004
    - Recruiting
    - Investigative Site ES015
  - Granada, Spain, 18014
    - Recruiting
    - Investigative Site ES003
  - Granada, Spain, 18016
    - Recruiting
    - Investigative Site ES013
  - Las Palmas de Gran Canaria, Spain, 35010
    - Recruiting
    - Investigative Site ES006
  - Madrid, Spain, 28041
    - Not yet recruiting
    - Investigative Site ES011
  - Madrid, Spain, 28034
    - Not yet recruiting
    - Investigative Site ES014
  - Madrid, Spain, 28040
    - Recruiting
    - Investigative Site ES008
  - Madrid, Spain, 28046
    - Recruiting
    - Investigative Site ES012
  - Manises, Spain, 46940
    - Recruiting
    - Investigative Site ES004
  - Pamplona, Spain, 31008
    - Not yet recruiting
    - Investigative Site ES022
  - Santiago de Compostela, Spain, 15706
    - Recruiting
    - Investigative Site ES002
  - Valencia, Spain, 46026
    - Not yet recruiting
    - Investigative Site ES018
Switzerland
- - Bern, Switzerland, 03010
    - Not yet recruiting
    - Investigative Site CH003
  - Buochs, Switzerland, 06374
    - Not yet recruiting
    - Investigative Site CH001
  - Zurich, Switzerland, 08091
    - Not yet recruiting
    - Investigative Site CH002
United Kingdom
- - Birmingham, United Kingdom, B15 2GW
    - Recruiting
    - Investigative Site GB003
  - Dudley, United Kingdom, DY1 2HQ
    - Not yet recruiting
    - Investigative Site GB001
  - Ipswich, United Kingdom, IP4 5PD
    - Not yet recruiting
    - Investigative Site GB011
  - Liverpool, United Kingdom, L14 3LB
    - Not yet recruiting
    - Investigative Site GB013
  - London, United Kingdom, E11 1NR
    - Not yet recruiting
    - Investigative Site GB012
  - London, United Kingdom, SE1 9RT
    - Not yet recruiting
    - Investigative Site GB014
  - Poole, United Kingdom, BH15 2JB
    - Not yet recruiting
    - Investigative Site GB006
  - Redhill, United Kingdom, RH1 5RH
    - Not yet recruiting
    - Investigative Site GB007
  - Salford, United Kingdom, M6 8HD
    - Recruiting
    - Investigative Site GB004
  - Wolverhampton, United Kingdom, WV10 0QP
    - Not yet recruiting
    - Investigative Site GB008
United States
- Alabama
  - Birmingham, Alabama, United States, 35244
    - Recruiting
    - Investigative Site US086
  - Montgomery, Alabama, United States, 36117
    - Not yet recruiting
    - Investigative Site US098
- Arizona
  - Phoenix, Arizona, United States, 85006
    - Recruiting
    - Investigative Site US004
  - Scottsdale, Arizona, United States, 85255
    - Not yet recruiting
    - Investigative Site US047
  - Scottsdale, Arizona, United States, 85255
    - Not yet recruiting
    - Investigative Site US124
  - Tucson, Arizona, United States, 85718
    - Not yet recruiting
    - Investigative Site US115
- Arkansas
  - Fayetteville, Arkansas, United States, 72703
    - Not yet recruiting
    - Investigative Site US113
  - Rogers, Arkansas, United States, 72758
    - Not yet recruiting
    - Investigative Site US009
- California
  - Fountain Valley, California, United States, 92708-3701
    - Recruiting
    - Investigative Site US076
  - Fremont, California, United States, 94538
    - Recruiting
    - Investigative Site US077
  - Huntington Beach, California, United States, 92647
    - Not yet recruiting
    - Investigative Site US071
  - Laguna Niguel, California, United States, 92677
    - Recruiting
    - Investigative Site US020
  - Los Angeles, California, United States, 90045
    - Recruiting
    - Investigative Site US067
  - Los Angeles, California, United States, 90033
    - Recruiting
    - Investigative Site US036
  - Northridge, California, United States, 91325
    - Recruiting
    - Investigative Site US060
  - Oakland, California, United States, 94611
    - Recruiting
    - Investigative Site US037
  - Santa Monica, California, United States, 90404
    - Recruiting
    - Investigative Site US089
  - Sherman Oaks, California, United States, 91403
    - Not yet recruiting
    - Investigative Site US080
- Florida
  - Aventura, Florida, United States, 33180
    - Not yet recruiting
    - Investigative Site US129
  - Boca Raton, Florida, United States, 33486
    - Recruiting
    - Investigative Site US002
  - Boca Raton, Florida, United States, 33428
    - Not yet recruiting
    - Investigative Site US116
  - Coral Gables, Florida, United States, 33134
    - Recruiting
    - Investigative Site US062
  - Coral Gables, Florida, United States, 33146
    - Recruiting
    - Investigative Site US084
  - Hialeah, Florida, United States, 33012
    - Recruiting
    - Investigative Site US017
  - Hollywood, Florida, United States, 33021-6746
    - Recruiting
    - Investigative Site US019
  - Margate, Florida, United States, 33063
    - Not yet recruiting
    - Investigative Site US044
  - Miami, Florida, United States, 33173
    - Not yet recruiting
    - Investigative Site US059
  - Miami, Florida, United States, 33136
    - Recruiting
    - Investigative Site US015
  - Miami Lakes, Florida, United States, 33014
    - Not yet recruiting
    - Investigative Site US079
  - Miami Lakes, Florida, United States, 33014
    - Recruiting
    - Investigative Site US072
  - North Miami Beach, Florida, United States, 33162
    - Recruiting
    - Investigative Site US023
  - Ocala, Florida, United States, 34470
    - Recruiting
    - Investigative Site US029
  - Tampa, Florida, United States, 33613
    - Recruiting
    - Investigative Site US005
  - Tampa, Florida, United States, 33615
    - Recruiting
    - Investigative Site US001
  - Tampa, Florida, United States, 33607
    - Not yet recruiting
    - Investigative Site US133
  - Tampa, Florida, United States, 33607
    - Recruiting
    - Investigative Site US035
  - West Palm Beach, Florida, United States, 33401
    - Recruiting
    - Investigative Site US066
  - West Palm Beach, Florida, United States, 33401
    - Recruiting
    - Investigative Site US070
- Georgia
  - Marietta, Georgia, United States, 30060-1047
    - Not yet recruiting
    - Investigative Site US051
  - Sandy Springs, Georgia, United States, 30328
    - Not yet recruiting
    - Investigative Site US103
  - Stonecrest, Georgia, United States, 30038
    - Not yet recruiting
    - Investigative Site US100
- Illinois
  - Chicago, Illinois, United States, 60602
    - Not yet recruiting
    - Investigative Site US125
  - Chicago, Illinois, United States, 60657
    - Recruiting
    - Investigative Site US093
  - Skokie, Illinois, United States, 60077
    - Not yet recruiting
    - Investigative Site US049
  - West Dundee, Illinois, United States, 60118
    - Recruiting
    - Investigative Site US039
- Indiana
  - Indianapolis, Indiana, United States, 46202
    - Not yet recruiting
    - Investigative Site US108
  - Indianapolis, Indiana, United States, 46250
    - Recruiting
    - Investigative Site US008
  - West Lafayette, Indiana, United States, 47906
    - Recruiting
    - Investigative Site US064
- Kentucky
  - Bowling Green, Kentucky, United States, 42104
    - Not yet recruiting
    - Investigative Site US056
- Louisiana
  - Baton Rouge, Louisiana, United States, 70809
    - Recruiting
    - Investigative Site US012
  - New Orleans, Louisiana, United States, 70115
    - Recruiting
    - Investigative Site US057
- Maryland
  - Baltimore, Maryland, United States, 21201
    - Not yet recruiting
    - Investigative Site US111
  - Baltimore, Maryland, United States, 21287-0876
    - Recruiting
    - Investigative Site US038
  - Glenn Dale, Maryland, United States, 20769
    - Not yet recruiting
    - Investigative Site US099
  - Marriottsville, Maryland, United States, 21104
    - Not yet recruiting
    - Investigative Site US053
  - Rockville, Maryland, United States, 20850
    - Not yet recruiting
    - Investigative Site US101
  - Rockville, Maryland, United States, 20850
    - Not yet recruiting
    - Investigative Site US127
- Massachusetts
  - Beverly, Massachusetts, United States, 01915
    - Withdrawn
    - Investigative Site US134
  - Boston, Massachusetts, United States, 02215
    - Recruiting
    - Investigative Site US030
  - Brighton, Massachusetts, United States, 02135
    - Recruiting
    - Investigative Site US048
- Michigan
  - Ann Arbor, Michigan, United States, 48103
    - Recruiting
    - Investigative Site US061
  - Auburn Hills, Michigan, United States, 48326
    - Not yet recruiting
    - Investigative Site US114
  - Detroit, Michigan, United States, 48202
    - Not yet recruiting
    - Investigative Site US120
  - Troy, Michigan, United States, 48084
    - Not yet recruiting
    - Investigative Site US128
  - Troy, Michigan, United States, 48084
    - Recruiting
    - Investigative Site US091
  - Waterford, Michigan, United States, 48328
    - Recruiting
    - Investigative Site US042
- Minnesota
  - Minneapolis, Minnesota, United States, 55455
    - Recruiting
    - Investigative Site US011
- Missouri
  - Saint Joseph, Missouri, United States, 64506
    - Recruiting
    - Investigative Site US088
  - St Louis, Missouri, United States, 63110
    - Recruiting
    - Investigative Site US016
- Nevada
  - Las Vegas, Nevada, United States, 89145
    - Not yet recruiting
    - Investigative Site US096
- New Hampshire
  - Portsmouth, New Hampshire, United States, 03801
    - Recruiting
    - Investigative Site US007
- New Jersey
  - Hackensack, New Jersey, United States, 07601
    - Not yet recruiting
    - Investigative Site US121
- New Mexico
  - Albuquerque, New Mexico, United States, 87131
    - Not yet recruiting
    - Investigative Site US118
- New York
  - East Syracuse, New York, United States, 13057
    - Not yet recruiting
    - Investigative Site US123
  - East Syracuse, New York, United States, 13057
    - Recruiting
    - Investigative Site US082
  - Kew Gardens, New York, United States, 11415
    - Not yet recruiting
    - Investigative Site US040
  - New York, New York, United States, 10956
    - Not yet recruiting
    - Investigative Site US075
  - New York, New York, United States, 10028-3135
    - Recruiting
    - Investigative Site US034
  - New York, New York, United States, 10128
    - Recruiting
    - Investigative Site US065
  - New York, New York, United States, 10075
    - Recruiting
    - Investigative Site US081
  - Rochester, New York, United States, 14642
    - Not yet recruiting
    - Investigative Site US050
  - Stony Brook, New York, United States, 11790
    - Not yet recruiting
    - Investigative Site US131
- North Carolina
  - Chapel Hill, North Carolina, United States, 27516
    - Recruiting
    - Investigative Site US031
- Ohio
  - Bexley, Ohio, United States, 43209
    - Recruiting
    - Investigative Site US028
  - Boardman, Ohio, United States, 44512
    - Not yet recruiting
    - Investigative Site US055
  - Cincinnati, Ohio, United States, 45219
    - Recruiting
    - Investigative Site US025
  - Columbus, Ohio, United States, 43230-5317
    - Not yet recruiting
    - Investigative Site US033
  - Columbus, Ohio, United States, 43215
    - Recruiting
    - Investigative Site US073
  - Dayton, Ohio, United States, 45324
    - Not yet recruiting
    - Investigative Site US130
  - Dublin, Ohio, United States, 43016
    - Not yet recruiting
    - Investigative Site US117
- Oklahoma
  - Oklahoma City, Oklahoma, United States, 73170
    - Recruiting
    - Investigative Site US085
- Pennsylvania
  - Philadelphia, Pennsylvania, United States, 19103
    - Not yet recruiting
    - Investigative Site US074
  - Plymouth Meeting, Pennsylvania, United States, 19462
    - Recruiting
    - Investigative Site US069
  - Yardley, Pennsylvania, United States, 19067
    - Not yet recruiting
    - Investigative Site US119
- Texas
  - Bellaire, Texas, United States, 77401
    - Recruiting
    - Investigative Site US021
  - Dallas, Texas, United States, 75246
    - Recruiting
    - Investigative Site US010
  - Dallas, Texas, United States, 75230
    - Recruiting
    - Investigative Site US078
  - Pflugerville, Texas, United States, 78660
    - Not yet recruiting
    - Investigative Site US054
  - San Antonio, Texas, United States, 78218
    - Recruiting
    - Investigative Site US083
  - Sugar Land, Texas, United States, 77479
    - Not yet recruiting
    - Investigative Site US126
  - Webster, Texas, United States, 77598
    - Recruiting
    - Investigative Site US068
- Utah
  - Murray, Utah, United States, 84107
    - Not yet recruiting
    - Investigative Site US122
  - South Jordan, Utah, United States, 84095
    - Recruiting
    - Investigative Site US063
- Virginia
  - Norfolk, Virginia, United States, 23502
    - Recruiting
    - Investigative Site US027
  - Richmond, Virginia, United States, 23226
    - Recruiting
    - Investigative Site US094
- Washington
  - Mill Creek, Washington, United States, 98012
    - Not yet recruiting
    - Investigative Site US132
  - Seattle, Washington, United States, 98168
    - Not yet recruiting
    - Investigative Site US092
  - Spokane, Washington, United States, 99202
    - Recruiting
    - Investigative Site US003

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

Adult
Older Adult

Accepts Healthy Volunteers

Description

Inclusion Criteria:

Ability to comprehend and willingness to sign a written ICF for the study.
Completed the treatment period of a predetermined, Incyte-sponsored, povorcitinib parent study without safety or tolerability concerns, per investigator's assessment.
Received clinical benefit from treatment with study drug during the parent study, as determined by the investigator.
Demonstrated compliance, as assessed by the investigator, with the parent Protocol requirements.
Willingness to avoid pregnancy or fathering children as defined in the protocol.
Willingness and ability to comply with the study Protocol and procedures.

Exclusion Criteria:

Had been permanently discontinued from study treatment during the parent study.
Had temporary study drug interruption due to safety and/or efficacy reasons at or after the final visit of the parent study.
Received at least 1 dose of either of the following therapies within the 28 days prior to starting treatment in this rollover study:
- Biologic immunomodulator (examples include but are not limited to adalimumab, bimekizumab, dupilumab, infliximab, nemolizumab, secukinumab).
- Live, attenuated vaccine.
Plans for administration of a live, attenuated vaccine during this study or within 8 weeks after the last dose of study drug.
Women who are pregnant (or who are considering pregnancy) or breastfeeding.
Known hypersensitivity or severe reaction to povorcitinib or excipients of povorcitinib and/or other products in the same class.
Currently enrolled in any other clinical study involving an investigational product or any other type of medical research judged not to be scientifically or medically compatible with this study.
Any condition that would, in the investigator's and/or sponsor's judgment, interfere with full participation in the study, including administration of study drug and attending required study visits; pose a significant risk to the participant; or interfere with interpretation of study data.

Other protocol-defined Inclusion/Exclusion Criteria may apply.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Primary Purpose: Treatment
Allocation: N/A
Interventional Model: Single Group Assignment
Masking: None (Open Label)

Number of Arms

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: povorcitinib Participants will receive povorcitinib treatment with the same schedule and dose options as the study in which they originally enrolled.	Drug: povorcitinib Study drug will be taken orally as defined by the protocol.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Proportion of participants with Treatment-Emergent Adverse Events (TEAEs) Time Frame: Up to approximately 3 years	Adverse events either reported for the first time in this Protocol or any AE ongoing and defined as treatment-emergent from the parent Protocol.	Up to approximately 3 years

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Proportion of participants with a total ANdT count of 0, 1, or 2 at each visit Time Frame: Up to approximately 3 years	ANdT count is defined as the total sum of abscesses, inflammatory nodules, and draining tunnels.	Up to approximately 3 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Incyte Corporation

Investigators

Study Director: Incyte Medical Monitor, Incyte Corporation

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 28, 2025

Primary Completion (Estimated)

February 28, 2028

Study Completion (Estimated)

February 28, 2028

Study Registration Dates

First Submitted

February 26, 2025

First Submitted That Met QC Criteria

February 26, 2025

First Posted (Actual)

March 3, 2025

Study Record Updates

Last Update Posted (Actual)

June 1, 2026

Last Update Submitted That Met QC Criteria

May 29, 2026

Last Verified

May 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

INCB054707-801
2024-520107-12-00 (Registry Identifier: EU CT Number)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

Incyte shares data with qualified external researchers after a research proposal is submitted. These requests are reviewed and approved by a review panel on the basis of scientific merit. All data provided is anonymized to respect the privacy of patients who have participated in the trial in line with applicable laws and regulations.

The trial data availability is according to the criteria and process described on https://www.incyte.com/our-company/compliance-and-transparency

IPD Sharing Time Frame

Data will be shared after the primary publication or 2 years after the study has ended for market authorized products and indications.

IPD Sharing Access Criteria

Data from eligible studies will be shared with qualified researchers according to the criteria and process described in the Data Sharing section of the www.incyteclinicaltrials.com website. For approved requests, the researchers will be granted access to anonymized data under the terms of a data sharing agreement.

IPD Sharing Supporting Information Type

STUDY_PROTOCOL
SAP

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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Study Overview

Status

Conditions

Intervention / Treatment

Study Type

Enrollment (Estimated)

Phase

Contacts and Locations

Study Contact

Study Contact Backup

Study Locations

Participation Criteria

Eligibility Criteria

Ages Eligible for Study

Accepts Healthy Volunteers

Description

Study Plan

How is the study designed?

Design Details

Number of Arms

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Secondary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Collaborators and Investigators

Sponsor

Investigators

Publications and helpful links

Helpful Links

Study record dates

Study Major Dates

Study Start (Actual)

Primary Completion (Estimated)

Study Completion (Estimated)

Study Registration Dates

First Submitted

First Submitted That Met QC Criteria

First Posted (Actual)

Study Record Updates

Last Update Posted (Actual)

Last Update Submitted That Met QC Criteria

Last Verified

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

IPD Plan Description

IPD Sharing Time Frame

IPD Sharing Access Criteria

IPD Sharing Supporting Information Type

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Studies a U.S. FDA-regulated device product

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