Isometric Versus Isotonic Trunk Muscle Strength Training on Lung Function in Heavy Smokers

January 21, 2026 updated by: Ahmed Mohamed Ahmed Abd El hady El Fahl,ph.d, MTI University

Smoking is a major public health concern, significantly affecting lung function and overall respiratory health. Heavy smoking leads to chronic obstructive pulmonary disease (COPD), emphysema, and a decline in lung capacity. Exercise interventions, particularly those targeting the trunk muscles; have demonstrated potential in improving respiratory function. Trunk muscle strength is essential for optimal breathing mechanics, as these muscles support the chest wall and aid in the expansion and contraction of the lungs.

There are two primary types of muscle strength training: isometric and isotonic. Isometric exercises involve static contractions where the muscle length does not change, while isotonic exercises involve dynamic movements with muscle lengthening and shortening. Each type of training offers unique benefits and impacts on muscle strength and endurance. This proposal aims to compare the effects of isometric versus isotonic trunk muscle strength training on lung function among heavy smokers, providing insights into their relative efficacy in improving respiratory health. Thus, the objective of this study was to explore the therapeutic effectiveness of Isometric versus Isotonic Trunk Muscle Strength Training on Lung Function in Heavy Smokers.

Study Overview

Status

Completed

Conditions

Detailed Description

Smoking is the practice of inhaling and exhaling smoke from burning plant material, most commonly tobacco, which contains the addictive substance nicotine. It is a major public health concern and the leading preventable cause of death and disease, as it damages nearly every organ and significantly increases the risk for many conditions like various cancers, heart disease, stroke, and respiratory diseases such as COPD. Quitting smoking can reverse many of these effects.

Smoking has long been identified as a major risk factor for a variety of health issues, and its impact on physical fitness and muscle power is an area of growing concern. Trunk muscle power, which is crucial for maintaining posture, stability, and overall functional movement, can be significantly affected by smoking. The primary mechanism through which smoking influences trunk muscle power lies in its detrimental effects on cardiovascular health and respiratory function. Nicotine and other harmful substances in cigarettes reduce oxygen supply to muscles, impairing their ability to generate power efficiently. This reduction in oxygen availability not only affects muscle endurance but also increases fatigue, hindering the muscle's capacity to function effectively during physical activities.

Moreover, smoking contributes to systemic inflammation and oxidative stress, both of which can compromise muscle health. Chronic inflammation can lead to muscle wasting and weaken the structural integrity of muscle fibers, including those of the trunk muscles. Oxidative stress, resulting from an imbalance between the production of free radicals and the body's ability to counteract their harmful effects, accelerates muscle degradation and impairs muscle recovery post-exercise. This is particularly detrimental to trunk muscles, which are constantly engaged in stabilizing and supporting the body. The cumulative effect of these processes results in diminished muscle power and functional capacity, ultimately affecting an individual's quality of life and ability to perform daily activities.

In addition, smoking is often associated with a sedentary lifestyle, which further exacerbates the decline in trunk muscle power. Smokers may experience reduced motivation to engage in physical exercise due to decreased lung capacity and higher perceived exertion during activities. This lack of exercise contributes to muscle atrophy and a loss of muscle strength and power. Thus, the combination of smoking-induced physiological changes and lifestyle factors creates a cycle of declining muscle power. Addressing smoking cessation and promoting physical activity can therefore be vital strategies in preserving trunk muscle power and overall health, highlighting the importance of integrating health education and smoking cessation programs in health curricula.

Study Type

Interventional

Enrollment (Actual)

90

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

      • Cairo, Egypt, 11311
        • faculty of physical therapy ,Cairo University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Individuals aged 20-45 years
  • Self-reported heavy smokers (defined as smoking ≥20 cigarettes per day
  • No participation in structured exercise programs in the past 6 months
  • Capable of performing physical exercises

Exclusion Criteria:

  • Diagnosed respiratory conditions other than smoking-related diseases (e.g., asthma)
  • Cardiovascular diseases prohibiting physical exercise
  • Recent surgeries or injuries affecting the trunk muscles
  • Pregnant women

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
No Intervention: Control
no intervention
Experimental: Isometric Trunk Muscle Strength
Participants will perform a series of isometric trunk exercises, such as planks and static bridges, three times a week
isometric trunk exercises, such as planks and static bridges, three times a week.
Experimental: Isotonic Trunk Muscle Strength
Participants will engage in isotonic exercises, such as sit-ups and Russian twists, also three times a week.
isotonic exercises, such as sit-ups and Russian twists, also three times a week.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Forced Expiratory Volume in 1 second (FEV1) Moreover, smoking contributes to systemic inflammation and oxidative stress, both of which can compromise muscle health. Chronic inflammation can lead to muscle wasting and weaken the structural integrity of
Time Frame: at baseline after 8 weeks
Forced Expiratory Volume in 1 second (FEV1) is a crucial measure of lung function that quantifies the volume of air a person can forcefully exhale in one second after a deep breath. It is used to assess the presence and severity of respiratory conditions
at baseline after 8 weeks
Forced Vital Capacity (FVC)
Time Frame: at base line after 8 weeks
Forced Vital Capacity (FVC) is the maximum amount of air a person can forcibly exhale from the lungs after taking the deepest breath possible.
at base line after 8 weeks
Peak Expiratory Flow (PEF)
Time Frame: at baseline and after 8 weeks
Peak Expiratory Flow (PEF) is the maximum speed at which a person can exhale, providing a measure of airway obstruction in conditions like asthma. It's assessed using a peak flow meter to monitor respiratory health and guide treatment decisions.
at baseline and after 8 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Trunk muscle strength
Time Frame: At baseline after 8 weeks
Trunk muscle strength refers to the power and endurance of the core muscles, including the abdominal and lower back, which are essential for maintaining posture, stability, and efficient movement in daily activities.
At baseline after 8 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 15, 2025

Primary Completion (Actual)

January 15, 2026

Study Completion (Actual)

January 16, 2026

Study Registration Dates

First Submitted

November 14, 2025

First Submitted That Met QC Criteria

November 18, 2025

First Posted (Actual)

November 21, 2025

Study Record Updates

Last Update Posted (Actual)

January 23, 2026

Last Update Submitted That Met QC Criteria

January 21, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • IRB # 31/7/2024-2025

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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