A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

June 2, 2026 updated by: Bristol-Myers Squibb

ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Compared to Durvalumab in Participants With Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy.

A study to evaluate Pumitamig versus Durvalumab following concurrent chemoradiation therapy in participants with unresectable stage III Non-small Cell Lung Cancer (NSCLC)

Study Overview

Status

Recruiting

Conditions

Non-small Cell Lung Cancer (NSCLC)

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

850

Phase

Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Name: First line of the email MUST contain NCT # and Site #.

Study Contact Backup

Name: BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
Phone Number: 855-907-3286
Email: Clinical.Trials@bms.com

Study Locations

Argentina
- - Buenos Aires, Argentina, 1426
    - Not yet recruiting
    - Local Institution - 0094
    - Contact:
      
      Site 0094
  - Buenos Aires, Argentina, 1430
    - Not yet recruiting
    - Local Institution - 0078
    - Contact:
      
      Site 0078
  - Buenos Aires, Argentina, C1199ABB
    - Not yet recruiting
    - Local Institution - 0761
    - Contact:
      
      Site 0761
  - Córdoba, Argentina, X5000
    - Not yet recruiting
    - Local Institution - 0608
    - Contact:
      
      Site 0608
  - Córdoba, Argentina, X5016
    - Not yet recruiting
    - Local Institution - 0313
    - Contact:
      
      Site 0313
- Buenos Aires
  - Buenas Aires, Buenos Aires, Argentina, C1049AAG
    - Not yet recruiting
    - Local Institution - 0093
    - Contact:
      
      Site 0093
  - Mar del Plata, Buenos Aires, Argentina, B7600FZN
    - Not yet recruiting
    - Local Institution - 0082
    - Contact:
      
      Site 0082
- Santa Fe Province
  - Rosario, Santa Fe Province, Argentina, 2000
    - Not yet recruiting
    - Local Institution - 0097
    - Contact:
      
      Site 0097
Australia
- - Wentworthville, Australia, NSW2145
    - Not yet recruiting
    - Local Institution - 0451
    - Contact:
      
      Site 0451
- New South Wales
  - Gosford, New South Wales, Australia, 2250
    - Recruiting
    - Gosford Hospital
    - Contact:
      
      Matthew Chan, Site 0456
      
      Phone Number: +61243209890
  - Penrith, New South Wales, Australia, 2750
    - Not yet recruiting
    - Local Institution - 0446
    - Contact:
      
      Site 0446
- South Australia
  - Elizabeth Vale, South Australia, Australia, 5112
    - Recruiting
    - Lyell McEwin Hospital
    - Contact:
      
      Joanne Tang, Site 0448
      
      Phone Number: 08 7117 7265
- Victoria
  - Ballarat Central, Victoria, Australia, 3350
    - Recruiting
    - Grampians Health
    - Contact:
      
      Wasek Faisal, Site 0442
      
      Phone Number: 61(03)53208500
  - Epping, Victoria, Australia, 3076
    - Not yet recruiting
    - Local Institution - 0458
    - Contact:
      
      Site 0458
- Western Australia
  - Joondalup, Western Australia, Australia, 6027
    - Recruiting
    - Joondalup Health Campus
    - Contact:
      
      Arman Hasani, Site 0476
      
      Phone Number: +61 8 9400 9897
Austria
- - Innsbruck, Austria, 6020
    - Not yet recruiting
    - Local Institution - 0190
    - Contact:
      
      Site 0190
  - Linz, Austria, 4020
    - Not yet recruiting
    - Local Institution - 0192
    - Contact:
      
      Site 0192
  - Vienna, Austria, A-1090
    - Not yet recruiting
    - Local Institution - 0207
    - Contact:
      
      Site 0207
Belgium
- Antwerpen
  - Brasschaat, Antwerpen, Belgium, 2930
    - Not yet recruiting
    - Local Institution - 0906
    - Contact:
      
      Site 0906
- Bruxelles-Capitale, Région de
  - Anderlecht, Bruxelles-Capitale, Région de, Belgium, 1070
    - Not yet recruiting
    - Local Institution - 0122
    - Contact:
      
      Site 0122
- Hainaut
  - Charleroi, Hainaut, Belgium, 6060
    - Not yet recruiting
    - Local Institution - 0111
    - Contact:
      
      Site 0111
- Limburg
  - Genk, Limburg, Belgium, 3600
    - Not yet recruiting
    - Local Institution - 0714
    - Contact:
      
      Site 0714
- Oost-Vlaanderen
  - Ghent, Oost-Vlaanderen, Belgium, 9000
    - Not yet recruiting
    - Local Institution - 0120
    - Contact:
      
      Site 0120
  - Sint-Niklaas, Oost-Vlaanderen, Belgium, B-9100
    - Not yet recruiting
    - Local Institution - 0117
    - Contact:
      
      Site 0117
- Vlaams-Brabant
  - Leuven, Vlaams-Brabant, Belgium, 3000
    - Not yet recruiting
    - Local Institution - 0116
    - Contact:
      
      Site 0116
Brazil
- - São Paulo, Brazil, 01246-000
    - Not yet recruiting
    - Local Institution - 0912
    - Contact:
      
      Site 0912
- Piauí
  - Teresina, Piauí, Brazil, 64049-200
    - Not yet recruiting
    - Local Institution - 0615
    - Contact:
      
      Site 0615
- Rio Grande do Norte
  - Natal/RN, Rio Grande do Norte, Brazil, 59062-000
    - Not yet recruiting
    - Local Institution - 0498
    - Contact:
      
      Site 0498
- Rio Grande do Sul
  - Porto Alegre, Rio Grande do Sul, Brazil, 90035-903
    - Not yet recruiting
    - Local Institution - 0619
    - Contact:
      
      Site 0619
- São Paulo
  - Barretos, São Paulo, Brazil, 14784
    - Not yet recruiting
    - Local Institution - 0535
    - Contact:
      
      Site 0535
  - São José do Rio Preto, São Paulo, Brazil, 15090-000
    - Not yet recruiting
    - Local Institution - 0538
    - Contact:
      
      Site 0538
Bulgaria
- - Haskovo, Bulgaria, 6304
    - Not yet recruiting
    - Local Institution - 0736
    - Contact:
      
      Site 0736
  - Rousse, Bulgaria, 7002
    - Not yet recruiting
    - Local Institution - 0551
    - Contact:
      
      Site 0551
  - Sofia, Bulgaria, 1431
    - Not yet recruiting
    - Local Institution - 0826
    - Contact:
      
      Site 0826
  - Sofia, Bulgaria, 1527
    - Not yet recruiting
    - Local Institution - 0732
    - Contact:
      
      Site 0732
  - Sofia, Bulgaria, 1680
    - Not yet recruiting
    - Local Institution - 0838
    - Contact:
      
      Site 0838
Canada
- - Québec, Canada, G1V 4G5
    - Recruiting
    - IUCPQ
    - Contact:
      
      Maude Dubé-Pelletier, Site 0682
      
      Phone Number: 418-656-8711
- Ontario
  - Ottawa, Ontario, Canada, K1H 8L6
    - Not yet recruiting
    - Local Institution - 0337
    - Contact:
      
      Site 0337
- Quebec
  - Montreal, Quebec, Canada, H3T 1M5
    - Not yet recruiting
    - Local Institution - 0644
    - Contact:
      
      Site 0644
Chile
- AN
  - Antofagasta, AN, Chile, 1240000
    - Not yet recruiting
    - Local Institution - 0910
    - Contact:
      
      Site 0910
- Arica y Parinacota Region
  - Las Condes, Arica y Parinacota Region, Chile, 7560908
    - Not yet recruiting
    - Local Institution - 0855
    - Contact:
      
      Site 0855
- Santiago Metropolitan
  - Santiago, Santiago Metropolitan, Chile, 7500921
    - Not yet recruiting
    - Local Institution - 0478
    - Contact:
      
      Site 0478
  - Santiago, Santiago Metropolitan, Chile, 7510032
    - Not yet recruiting
    - Local Institution - 0037
    - Contact:
      
      Site 0037
  - Santiago, Santiago Metropolitan, Chile, 8420383
    - Not yet recruiting
    - Local Institution - 0077
    - Contact:
      
      Site 0077
- Valparaiso
  - Viña del Mar, Valparaiso, Chile, 2520612
    - Not yet recruiting
    - Local Institution - 0328
    - Contact:
      
      Site 0328
China
- - Guangzhou, China, 510060
    - Not yet recruiting
    - Local Institution - 0561
    - Contact:
      
      Site 0561
  - Hangzhou, China, 215006
    - Not yet recruiting
    - Local Institution - 0301
    - Contact:
      
      Site 0301
  - Shanghai Shi, China, 200030
    - Not yet recruiting
    - Local Institution - 0537
    - Contact:
      
      Site 0537
  - Xi'an, China, 710061
    - Not yet recruiting
    - Local Institution - 0564
    - Contact:
      
      Site 0564
- Beijing Municipality
  - Beijing, Beijing Municipality, China, 100142
    - Not yet recruiting
    - Local Institution - 0754
    - Contact:
      
      Site 0754
- Chongqing Municipality
  - Chongqing, Chongqing Municipality, China, 400030
    - Not yet recruiting
    - Local Institution - 0308
    - Contact:
      
      Site 0308
- Fujian
  - Fuzhou, Fujian, China, 350014
    - Not yet recruiting
    - Local Institution - 0245
    - Contact:
      
      Site 0245
- Guangdong
  - Shantou, Guangdong, China, 515041
    - Recruiting
    - Cancer Hospital of Shantou University Medical College
    - Contact:
      
      Wen Lin, Site 0298
      
      Phone Number: 13612388011
  - Shenzhen, Guangdong, China, 518036
    - Not yet recruiting
    - Local Institution - 0919
    - Contact:
      
      Site 0919
- Henan
  - Zhengzhou, Henan, China, 450008
    - Not yet recruiting
    - Local Institution - 0249
    - Contact:
      
      Site 0249
- Hubei
  - Jingzhou, Hubei, China
    - Not yet recruiting
    - Local Institution - 0911
    - Contact:
      
      Site 0911
  - Wuhan, Hubei, China, 430014
    - Not yet recruiting
    - Local Institution - 0921
    - Contact:
      
      Site 0921
  - Wuhan, Hubei, China, 430030
    - Withdrawn
    - Local Institution - 0813
- Hunan
  - Changsha, Hunan, China, 410031
    - Not yet recruiting
    - Local Institution - 0489
    - Contact:
      
      Site 0489
- Jiangsu
  - Suzhou, Jiangsu, China, 215006
    - Not yet recruiting
    - Local Institution - 0918
    - Contact:
      
      Site 0918
- Jiangxi
  - Nanchang, Jiangxi, China, 330006
    - Not yet recruiting
    - Local Institution - 0254
    - Contact:
      
      Site 0254
- Liaoning
  - Shenyang, Liaoning, China, 110042
    - Not yet recruiting
    - Local Institution - 0242
    - Contact:
      
      Site 0242
- Shaanxi
  - Xi'an, Shaanxi, China, 710004
    - Not yet recruiting
    - Local Institution - 0527
    - Contact:
      
      Site 0527
- Shandong
  - Jinan, Shandong, China, 250117
    - Not yet recruiting
    - Local Institution - 0297
    - Contact:
      
      Site 0297
  - Jinan, Shandong, China, 250012
    - Not yet recruiting
    - Local Institution - 0528
    - Contact:
      
      Site 0528
- Shanghai Municipality
  - Shanghai, Shanghai Municipality, China, 200433
    - Not yet recruiting
    - Local Institution - 0248
    - Contact:
      
      Site 0248
- Shanxi
  - Taiyuan, Shanxi, China, 030000
    - Not yet recruiting
    - Local Institution - 0542
    - Contact:
      
      Site 0542
- Sichuan
  - Chengdu, Sichuan, China, 610041
    - Not yet recruiting
    - Local Institution - 0835
    - Contact:
      
      Site 0835
  - Chengdu, Sichuan, China, 610066
    - Not yet recruiting
    - Local Institution - 0440
    - Contact:
      
      Site 0440
- Zhejiang
  - Hangzhou, Zhejiang, China, 310000
    - Not yet recruiting
    - Local Institution - 0719
    - Contact:
      
      Site 0719
  - Linhai, Zhejiang, China, 317000
    - Not yet recruiting
    - Local Institution - 0253
    - Contact:
      
      Site 0253
France
- - Limoges, France, 87042
    - Not yet recruiting
    - Local Institution - 0025
    - Contact:
      
      Site 0025
  - Marseille, France, 13915
    - Not yet recruiting
    - Local Institution - 0024
    - Contact:
      
      Site 0024
  - Paris, France, 75014
    - Not yet recruiting
    - Local Institution - 0026
    - Contact:
      
      Site 0026
- Aquitaine
  - Bordeaux, Aquitaine, France, 33076
    - Not yet recruiting
    - Local Institution - 0029
    - Contact:
      
      Site 0029
- Auvergne-Rhône-Alpes
  - Lyon Cedex08, Auvergne-Rhône-Alpes, France, 69373
    - Not yet recruiting
    - Local Institution - 0130
    - Contact:
      
      Site 0130
- Côte-d'Or
  - Dijon, Côte-d'Or, France, 21079
    - Not yet recruiting
    - Local Institution - 0129
    - Contact:
      
      Site 0129
- Hauts-de-France
  - Lille, Hauts-de-France, France, 59037
    - Not yet recruiting
    - Local Institution - 0716
    - Contact:
      
      Site 0716
- Hérault
  - Montpellier, Hérault, France, 34298
    - Not yet recruiting
    - Local Institution - 0028
    - Contact:
      
      Site 0028
- Loire-Atlantique
  - Saint-Herblain, Loire-Atlantique, France, 44800
    - Not yet recruiting
    - Local Institution - 0127
    - Contact:
      
      Site 0127
- Midi-Pyrénées
  - Toulouse, Midi-Pyrénées, France, 31400
    - Not yet recruiting
    - Local Institution - 0023
    - Contact:
      
      Site 0023
- Val-de-Marne
  - Villejuif, Val-de-Marne, France, 94800
    - Not yet recruiting
    - Local Institution - 0689
    - Contact:
      
      Site 0689
Germany
- - Berlin, Germany, 10117
    - Not yet recruiting
    - Local Institution - 0217
    - Contact:
      
      Site 0217
  - Berlin, Germany, 14165
    - Not yet recruiting
    - Local Institution - 0215
    - Contact:
      
      Site 0215
  - Gröbenzell, Germany, 82194
    - Not yet recruiting
    - Local Institution - 0178
    - Contact:
      
      Site 0178
  - Göttingen, Germany, 37075
    - Not yet recruiting
    - Local Institution - 0169
    - Contact:
      
      Site 0169
  - Haile, Germany, 06120
    - Not yet recruiting
    - Local Institution - 0199
    - Contact:
      
      Site 0199
  - Hamburg, Germany, 22045
    - Not yet recruiting
    - Local Institution - 0299
    - Contact:
      
      Site 0299
  - Immenhausen, Germany, 34376
    - Not yet recruiting
    - Local Institution - 0186
    - Contact:
      
      Site 0186
  - Regensburg, Germany, 93053
    - Not yet recruiting
    - Local Institution - 0187
    - Contact:
      
      Site 0187
- Bavaria
  - Augsburg, Bavaria, Germany, 86156
    - Not yet recruiting
    - Local Institution - 0739
    - Contact:
      
      Site 0739
- Rhineland-Palatinate
  - Koblenz, Rhineland-Palatinate, Germany, 56073
    - Not yet recruiting
    - Local Institution - 0265
    - Contact:
      
      Site 0265
  - Ludwigshafen am Rhein, Rhineland-Palatinate, Germany, 67063
    - Not yet recruiting
    - Local Institution - 0174
    - Contact:
      
      Site 0174
- Schleswig-Holstein
  - Kiel, Schleswig-Holstein, Germany, 24105
    - Not yet recruiting
    - Local Institution - 0172
    - Contact:
      
      Site 0172
- Thuringia
  - Jena, Thuringia, Germany, 7747
    - Not yet recruiting
    - Local Institution - 0182
    - Contact:
      
      Site 0182
Greece
- - Athens, Greece, 11 527
    - Not yet recruiting
    - Local Institution - 0391
    - Contact:
      
      Site 0391
  - Athens, Greece, 115 26
    - Not yet recruiting
    - Local Institution - 0323
    - Contact:
      
      Site 0323
  - Athens, Greece, 115 27
    - Not yet recruiting
    - Local Institution - 0324
    - Contact:
      
      Site 0324
  - Thessaloniki, Greece, 56429
    - Not yet recruiting
    - Local Institution - 0697
    - Contact:
      
      Site 0697
- Thessaloníki
  - Thessaloniki, Thessaloníki, Greece, 570 10
    - Not yet recruiting
    - Local Institution - 0416
    - Contact:
      
      Site 0416
- Thessalía
  - Larissa, Thessalía, Greece, 41110
    - Not yet recruiting
    - Local Institution - 0321
    - Contact:
      
      Site 0321
Hong Kong
- - Hksar, Hong Kong, 999077
    - Not yet recruiting
    - Local Institution - 0193
    - Contact:
      
      Site 0193
  - Shatin, Hong Kong
    - Not yet recruiting
    - Local Institution - 0764
    - Contact:
      
      Site 0764
- NT
  - Tuenmen, NT, Hong Kong
    - Not yet recruiting
    - Local Institution - 0457
    - Contact:
      
      Site 0457
Hungary
- - Budapest, Hungary, 1121
    - Not yet recruiting
    - Local Institution - 0138
    - Contact:
      
      Site 0138
  - Farkasgyepű, Hungary, 8582
    - Not yet recruiting
    - Local Institution - 0776
    - Contact:
      
      Site 0776
  - Törökbálint, Hungary, 2045
    - Not yet recruiting
    - Local Institution - 0696
    - Contact:
      
      Site 0696
- Bács-Kiskun county
  - Kecskemét, Bács-Kiskun county, Hungary, 6000
    - Not yet recruiting
    - Local Institution - 0139
    - Contact:
      
      Site 0139
- Jász-Nagykun-Szolnok
  - Szolnok, Jász-Nagykun-Szolnok, Hungary, 5000
    - Not yet recruiting
    - Local Institution - 0787
    - Contact:
      
      Site 0787
India
- - Delhi, India, 110029
    - Not yet recruiting
    - Local Institution - 0547
    - Contact:
      
      Site 0547
  - Pune, India, 411001
    - Not yet recruiting
    - Local Institution - 0659
    - Contact:
      
      Site 0659
- Andhra Pradesh
  - Eluru, Andhra Pradesh, India, 534002
    - Not yet recruiting
    - Local Institution - 0840
    - Contact:
      
      Site 0840
- Gujarat
  - Goraj, Gujarat, India, 391760
    - Not yet recruiting
    - Local Institution - 0927
    - Contact:
      
      Site 0927
- Kerala
  - Pūlakkōd, Kerala, India, 673601
    - Not yet recruiting
    - Local Institution - 0548
    - Contact:
      
      Site 0548
- Maharashtra
  - Aurangabad, Maharashtra, India, 431002
    - Not yet recruiting
    - Local Institution - 0864
    - Contact:
      
      Site 0864
  - Mumbai, Maharashtra, India, 400012
    - Not yet recruiting
    - Local Institution - 0660
    - Contact:
      
      Site 0660
  - Mumbai, Maharashtra, India, 400036
    - Not yet recruiting
    - Local Institution - 0663
    - Contact:
      
      Site 0663
  - Nagpur, Maharashtra, India, 440001
    - Not yet recruiting
    - Local Institution - 0661
    - Contact:
      
      Site 0661
- National Capital Territory of Delhi
  - Dwarka, National Capital Territory of Delhi, India, 110075
    - Not yet recruiting
    - Local Institution - 0664
    - Contact:
      
      Site 0664
  - New Delhi, National Capital Territory of Delhi, India, 110085
    - Not yet recruiting
    - Local Institution - 0856
    - Contact:
      
      Site 0856
- Telangana
  - Hyderabad, Telangana, India, 500033
    - Not yet recruiting
    - Local Institution - 0657
    - Contact:
      
      Site 0657
Ireland
- - Cork, Ireland, T12K199
    - Not yet recruiting
    - Local Institution - 0276
    - Contact:
      
      Site 0276
  - Dublin, Ireland, D08 E9P6
    - Not yet recruiting
    - Local Institution - 0270
    - Contact:
      
      Site 0270
  - Dublin, Ireland, D9
    - Not yet recruiting
    - Local Institution - 0070
    - Contact:
      
      Site 0070
Italy
- - Aviano (PN), Italy, 33081
    - Not yet recruiting
    - Local Institution - 0269
    - Contact:
      
      Site 0269
  - Milan, Italy, 20132
    - Not yet recruiting
    - Local Institution - 0668
    - Contact:
      
      Site 0668
  - Milan, Italy, 20141
    - Not yet recruiting
    - Local Institution - 0667
    - Contact:
      
      Site 0667
  - Naples, Italy, 80131
    - Not yet recruiting
    - Local Institution - 0275
    - Contact:
      
      Site 0275
  - Parma, Italy, 43126
    - Not yet recruiting
    - Local Institution - 0390
    - Contact:
      
      Site 0390
  - Ravenna, Italy, 48121
    - Not yet recruiting
    - Local Institution - 0670
    - Contact:
      
      Site 0670
- Piedmont
  - Orbassano, Piedmont, Italy, 10043
    - Not yet recruiting
    - Local Institution - 0304
    - Contact:
      
      Site 0304
- Roma
  - Rome, Roma, Italy, 00128
    - Not yet recruiting
    - Local Institution - 0669
    - Contact:
      
      Site 0669
Japan
- - Hirakata-shi, Japan, 573-1191
    - Not yet recruiting
    - Local Institution - 0016
    - Contact:
      
      Site 0016
  - Minami-Ku, Fukuoka, Japan, 811-1347
    - Not yet recruiting
    - Local Institution - 0009
    - Contact:
      
      Site 0009
  - Sagamihara, Japan, 252-0375
    - Not yet recruiting
    - Local Institution - 0157
    - Contact:
      
      Site 0157
  - Sendai, Japan, 980-8574
    - Not yet recruiting
    - Local Institution - 0759
    - Contact:
      
      Site 0759
- Aichi-ken
  - Nagoya, Aichi-ken, Japan, 464-8681
    - Not yet recruiting
    - Local Institution - 0014
    - Contact:
      
      Site 0014
- Hyōgo
  - Kobe, Hyōgo, Japan, 650-0017
    - Not yet recruiting
    - Local Institution - 0701
    - Contact:
      
      Site 0701
  - Nishinomiya, Hyōgo, Japan, 663-8501
    - Recruiting
    - Hyogo Medical University Hospital
    - Contact:
      
      Takashi Kijima, Site 0154
      
      Phone Number: 81798456111
- Kanagawa
  - Yokohama, Kanagawa, Japan, 2418515
    - Recruiting
    - Kanagawa Cancer Center
    - Contact:
      
      Shuji Murakami, Site 0008
      
      Phone Number: 81455202222
- Miyagi
  - Sendai, Miyagi, Japan, 980-0873
    - Not yet recruiting
    - Local Institution - 0001
    - Contact:
      
      Site 0001
- Okayama-ken
  - Okayama, Okayama-ken, Japan, 700-8558
    - Not yet recruiting
    - Local Institution - 0907
    - Contact:
      
      Site 0907
- Osaka
  - Sakai, Osaka, Japan, 590-0197
    - Recruiting
    - Kindai University Hospital
    - Contact:
      
      Hidetoshi Hayashi, Site 0002
      
      Phone Number: 81723681184
- Saitama-Pref
  - Hidaka, Saitama-Pref, Japan, 350-1298
    - Not yet recruiting
    - Local Institution - 0149
    - Contact:
      
      Site 0149
- Shizuoka
  - Hamamatsu, Shizuoka, Japan, 431-3192
    - Recruiting
    - Hamamatsu University Hospital
    - Contact:
      
      Naoki Inui, Site 0158
      
      Phone Number: 81534352356
- Tokyo
  - Bunkyo Ku, Tokyo, Japan, 113-8677
    - Not yet recruiting
    - Local Institution - 0018
    - Contact:
      
      Site 0018
Mexico
- - Puebla City, Mexico, 72530
    - Not yet recruiting
    - Local Institution - 0914
    - Contact:
      
      Site 0914
  - Querétaro, Mexico, 76000
    - Not yet recruiting
    - Local Institution - 0349
    - Contact:
      
      Site 0349
- Coahuila
  - Saltillo, Coahuila, Mexico, 25279
    - Not yet recruiting
    - Local Institution - 0772
    - Contact:
      
      Site 0772
- Estado de Baja California
  - Tijuana, Estado de Baja California, Mexico, 22010
    - Not yet recruiting
    - Local Institution - 0815
    - Contact:
      
      Site 0815
- Jalisco
  - Zapopan, Jalisco, Mexico, 45050
    - Not yet recruiting
    - Local Institution - 0699
    - Contact:
      
      Site 0699
- Nuevo León
  - Monterrey, Nuevo León, Mexico, 64460
    - Not yet recruiting
    - Local Institution - 0330
    - Contact:
      
      Site 0330
Netherlands
- - Groningen, Netherlands, 9713 GZ
    - Not yet recruiting
    - Local Institution - 0089
    - Contact:
      
      Site 0089
  - Tilburg, Netherlands, 5000 LA
    - Not yet recruiting
    - Local Institution - 0092
    - Contact:
      
      Site 0092
- Gelderland
  - Nijmegen, Gelderland, Netherlands, 6525 GA
    - Not yet recruiting
    - Local Institution - 0243
    - Contact:
      
      Site 0243
- North Brabant
  - Breda, North Brabant, Netherlands, 4818 CK
    - Not yet recruiting
    - Local Institution - 0095
    - Contact:
      
      Site 0095
- North Holland
  - Amsterdam, North Holland, Netherlands, 1081 HV
    - Not yet recruiting
    - Local Institution - 0091
    - Contact:
      
      Site 0091
- Overijssel
  - Zwolle, Overijssel, Netherlands, 8025 AB
    - Not yet recruiting
    - Local Institution - 0087
    - Contact:
      
      Site 0087
Poland
- - Opole, Poland, 45-372
    - Not yet recruiting
    - Local Institution - 0680
    - Contact:
      
      Site 0680
- Lublin Voivodeship
  - Lublin, Lublin Voivodeship, Poland, 20-954
    - Not yet recruiting
    - Local Institution - 0473
    - Contact:
      
      Site 0473
- Podkarpackie Voivodeship
  - Przemyśl, Podkarpackie Voivodeship, Poland, 37-700
    - Not yet recruiting
    - Local Institution - 0556
    - Contact:
      
      Site 0556
- Silesian Voivodeship
  - Katowice, Silesian Voivodeship, Poland, 40-853
    - Not yet recruiting
    - Local Institution - 0681
    - Contact:
      
      Site 0681
Romania
- - Bucharest, Romania, 050098
    - Not yet recruiting
    - Local Institution - 0046
    - Contact:
      
      Site 0046
  - Cluj-Napoca, Romania, 400015
    - Not yet recruiting
    - Local Institution - 0168
    - Contact:
      
      Site 0168
  - Craiova, Romania, 200347
    - Not yet recruiting
    - Local Institution - 0045
    - Contact:
      
      Site 0045
  - Floresti/ Cluj, Romania, 407280
    - Not yet recruiting
    - Local Institution - 0058
    - Contact:
      
      Site 0058
  - Iași, Romania, 700106
    - Not yet recruiting
    - Local Institution - 0184
    - Contact:
      
      Site 0184
  - Iași, Romania, 700483
    - Not yet recruiting
    - Local Institution - 0164
    - Contact:
      
      Site 0164
- Bucharest
  - Bucharest, Bucharest, Romania, 020335
    - Not yet recruiting
    - Local Institution - 0219
    - Contact:
      
      Site 0219
Singapore
- - Singapore, Singapore, 308442
    - Not yet recruiting
    - Local Institution - 0647
    - Contact:
      
      Site 0647
- Central Singapore
  - Singapore, Central Singapore, Singapore, 168583
    - Not yet recruiting
    - Local Institution - 0650
    - Contact:
      
      Site 0650
South Korea
- Chungcheongbuk-do [Chungbuk]
  - Cheongju-si, Chungcheongbuk-do [Chungbuk], South Korea, 28644
    - Recruiting
    - Chungbuk National University Hospital
    - Contact:
      
      Ki Hyeong Lee, Site 0052
      
      Phone Number: 82432696015
- Kyǒnggi-do
  - Seongnam, Kyǒnggi-do, South Korea, 13620
    - Recruiting
    - Seoul National University Bundang Hospital
    - Contact:
      
      Yu Jung Kim, Site 0151
      
      Phone Number: +82-31-787-7041
- Seoul-teukbyeolsi [Seoul]
  - Seoul, Seoul-teukbyeolsi [Seoul], South Korea, 03080
    - Recruiting
    - Seoul National University Hospital
    - Contact:
      
      Jeonghwan Youk, Site 0055
      
      Phone Number: 01097705707
  - Seoul, Seoul-teukbyeolsi [Seoul], South Korea, 06351
    - Recruiting
    - Samsung Medical Center
    - Contact:
      
      Jin Seok Ahn, Site 0035
      
      Phone Number: 821099333453
  - Seoul, Seoul-teukbyeolsi [Seoul], South Korea, 03722
    - Recruiting
    - Severance Hospital, Yonsei University Health System
    - Contact:
      
      Hye Ryun Kim, Site 0063
      
      Phone Number: 82222284190
  - Seoul, Seoul-teukbyeolsi [Seoul], South Korea, 05505
    - Recruiting
    - Asan Medical Center
    - Contact:
      
      Dae Ho Lee, Site 0064
      
      Phone Number: 82230103214
Spain
- - Barakaldo, Spain, 48903
    - Not yet recruiting
    - Local Institution - 0086
    - Contact:
      
      Site 0086
  - Barcelona, Spain, 08003
    - Not yet recruiting
    - Local Institution - 0043
    - Contact:
      
      Site 0043
  - Barcelona, Spain, 08041
    - Not yet recruiting
    - Local Institution - 0042
    - Contact:
      
      Site 0042
  - Madrid, Spain, 28041
    - Not yet recruiting
    - Local Institution - 0049
    - Contact:
      
      Site 0049
  - Málaga, Spain, 29010
    - Not yet recruiting
    - Local Institution - 0570
    - Contact:
      
      Site 0570
  - Seville, Spain, 41009
    - Not yet recruiting
    - Local Institution - 0061
    - Contact:
      
      Site 0061
  - Valencia, Spain, 46010
    - Not yet recruiting
    - Local Institution - 0066
    - Contact:
      
      Site 0066
  - Zaragoza, Spain, 50009
    - Not yet recruiting
    - Local Institution - 0044
    - Contact:
      
      Site 0044
- Barcelona [Barcelona]
  - L'Hospitalet Del Llobregat, Barcelona [Barcelona], Spain, 08908
    - Not yet recruiting
    - Local Institution - 0041
    - Contact:
      
      Site 0041
Sweden
- - Uppsala, Sweden, 751 85
    - Not yet recruiting
    - Local Institution - 0034
    - Contact:
      
      Site 0034
- Gävleborgs Län [se-21]
  - Gävle, Gävleborgs Län [se-21], Sweden, 80187
    - Not yet recruiting
    - Local Institution - 0033
    - Contact:
      
      Site 0033
- Stockholms Län [se-01]
  - Solna, Stockholms Län [se-01], Sweden, 171 64
    - Not yet recruiting
    - Local Institution - 0032
    - Contact:
      
      Site 0032
Switzerland
- - Basel, Switzerland, 4031
    - Recruiting
    - Universitaetsspital Basel
    - Contact:
      
      Benjamin Thiele, Site 0222
  - Bellinzona, Switzerland, CH-6500
    - Recruiting
    - Ospedale Regionale Bellinzona e Valli
    - Contact:
      
      Martina Imbimbo, Site 0166
      
      Phone Number: 41(0)918119631
  - Münsterlingen, Switzerland, 8596
    - Recruiting
    - Kantonsspital Münsterlingen - Spital Thurgau AG
    - Contact:
      
      Ioannis Metaxas, Site 0738
      
      Phone Number: +41581447850
  - Sankt Gallen, Switzerland, 9007
    - Recruiting
    - Kantonsspital St Gallen
    - Contact:
      
      Markus Joerger, Site 0165
      
      Phone Number: 41714941111
Taiwan
- - Chiayi City, Taiwan, 60090
    - Not yet recruiting
    - Local Institution - 0735
    - Contact:
      
      Site 0735
  - Taipei, Taiwan, 10002
    - Recruiting
    - National Taiwan University Hospital
    - Contact:
      
      Jin-Yuan Shih, Site 0726
      
      Phone Number: 88622312345662905
  - Taipei, Taiwan, 220
    - Not yet recruiting
    - Local Institution - 0729
    - Contact:
      
      Site 0729
- Hsinchu
  - Zhubei, Hsinchu, Taiwan, 302
    - Recruiting
    - National Taiwan University Hospital - Hsinchu branch
    - Contact:
      
      Jih-Hsiang Lee, Site 0734
      
      Phone Number: 886223368239
Thailand
- - Bangkok, Thailand, 10700
    - Not yet recruiting
    - Local Institution - 0733
    - Contact:
      
      Site 0733
  - Chiang Mai, Thailand, 50200
    - Not yet recruiting
    - Local Institution - 0917
    - Contact:
      
      Site 0917
  - Khon Kaen, Thailand, 40002
    - Not yet recruiting
    - Local Institution - 0160
    - Contact:
      
      Site 0160
  - Songkhla, Thailand, 90110
    - Not yet recruiting
    - Local Institution - 0728
    - Contact:
      
      Site 0728
Turkey (Türkiye)
- - Adana, Turkey (Türkiye), 01140
    - Not yet recruiting
    - Local Institution - 0099
    - Contact:
      
      Site 0099
  - Adana, Turkey (Türkiye), 01370
    - Not yet recruiting
    - Local Institution - 0113
    - Contact:
      
      Site 0113
  - Antalya, Turkey (Türkiye), 07100
    - Not yet recruiting
    - Local Institution - 0198
    - Contact:
      
      Site 0198
  - Istanbul, Turkey (Türkiye), 34214
    - Not yet recruiting
    - Local Institution - 0096
    - Contact:
      
      Site 0096
  - Istanbul, Turkey (Türkiye), 34732
    - Not yet recruiting
    - Local Institution - 0107
    - Contact:
      
      Site 0107
  - Çankaya, Turkey (Türkiye), 06680
    - Not yet recruiting
    - Local Institution - 0109
    - Contact:
      
      Site 0109
United Kingdom
- - Cambridge, United Kingdom, CB2 2QQ
    - Recruiting
    - Addenbrooke's Hospital
    - Contact:
      
      Huiqi Yang, Site 0672
      
      Phone Number: +44(0)1223 805000
  - Cardiff, United Kingdom, CF14 2TL
    - Recruiting
    - Velindre Cancer Centre
    - Contact:
      
      paul shaw, Site 0289
      
      Phone Number: +44 29 2061 5888
  - Guildford, United Kingdom, GU2 7XX
    - Not yet recruiting
    - Local Institution - 0257
    - Contact:
      
      Site 0257
  - Leeds, United Kingdom, LS9 7TF
    - Withdrawn
    - Local Institution - 0693
  - Liverpool, United Kingdom, L9 7BA
    - Recruiting
    - Clatterbridge Cancer Centre - Liverpool
    - Contact:
      
      Carles Escriu, Site 0232
      
      Phone Number: +44 151 556 5000
  - London, United Kingdom, NW1 2BU
    - Recruiting
    - University College London Hospital
    - Contact:
      
      Crispin Hiley, Site 0296
      
      Phone Number: +44 20 3456 7890
  - London, United Kingdom, SW3 6JJ
    - Recruiting
    - Royal Marsden Hospital (Chelsea)
    - Contact:
      
      Michael Davidson, Site 0235
      
      Phone Number: +44 20 7352 8171
  - Middlesex, United Kingdom, DA146LT
    - Not yet recruiting
    - Local Institution - 0533
    - Contact:
      
      Site 0533
  - Sutton, United Kingdom, SM2 5PT
    - Recruiting
    - The Royal Marsden NHS Foundation Trust
    - Contact:
      
      Michael Davidson, Site 0913
      
      Phone Number: +44(0)20 8642 6011
- Lancashire
  - Manchester, Lancashire, United Kingdom, M20 4BX
    - Recruiting
    - The Christie NHS Foundation Trust
    - Contact:
      
      Martin Igor Gomez Randulfe Rodriguez, Site 0239
      
      Phone Number: +44(0)161 446 3000
United States
- Alabama
  - Daphne, Alabama, United States, 36526
    - Recruiting
    - Southern Cancer Center Pc
    - Contact:
      
      Michael Meshad, Site 0898
      
      Phone Number: 111-111-1111
- Arizona
  - Chandler, Arizona, United States, 85224
    - Not yet recruiting
    - Local Institution - 0780
    - Contact:
      
      Site 0780
- Colorado
  - Golden, Colorado, United States, 80401
    - Not yet recruiting
    - Local Institution - 0585
    - Contact:
      
      Site 0585
- Delaware
  - Newark, Delaware, United States, 19713
    - Recruiting
    - Medical Oncology Hematology Consultants, PA
    - Contact:
      
      Jamal Misleh, Site 0896
      
      Phone Number: 302-366-1200
- Florida
  - Ocala, Florida, United States, 34474
    - Not yet recruiting
    - Local Institution - 0711
    - Contact:
      
      Site 0711
- Georgia
  - Marietta, Georgia, United States, 30060
    - Not yet recruiting
    - Local Institution - 0756
    - Contact:
      
      Site 0756
- Illinois
  - Chicago, Illinois, United States, 60637
    - Not yet recruiting
    - Local Institution - 0398
    - Contact:
      
      Site 0398
  - Evanston, Illinois, United States, 60201
    - Not yet recruiting
    - Local Institution - 0850
    - Contact:
      
      Site 0850
  - Peoria, Illinois, United States, 61615
    - Recruiting
    - Illinois Cancer Care
    - Contact:
      
      Srinivas Jujjavarapu, Site 0897
      
      Phone Number: 309-243-3000
- Indiana
  - Fort Wayne, Indiana, United States, 46804
    - Recruiting
    - Fort Wayne Medical Oncology and Hematology
    - Contact:
      
      Ahad Sadiq, Site 0317
      
      Phone Number: 260-436-0800
- Kentucky
  - Lexington, Kentucky, United States, 40536-0284
    - Not yet recruiting
    - Local Institution - 0656
    - Contact:
      
      Site 0656
- Massachusetts
  - Boston, Massachusetts, United States, 02114-2621
    - Not yet recruiting
    - Local Institution - 0603
    - Contact:
      
      Site 0603
- Michigan
  - Detroit, Michigan, United States, 48201
    - Not yet recruiting
    - Local Institution - 0419
    - Contact:
      
      Site 0419
- Minnesota
  - Maple Grove, Minnesota, United States, 55369
    - Recruiting
    - Minnesota Oncology Hematology
    - Contact:
      
      Daniel Mundt, Site 0322
  - Saint Paul, Minnesota, United States, 55102
    - Not yet recruiting
    - Local Institution - 0142
    - Contact:
      
      Site 0142
- Missouri
  - Columbia, Missouri, United States, 65201
    - Recruiting
    - Missouri Cancer Associates
    - Contact:
      
      Caleb Smith, Site 0900
- New York
  - New York, New York, United States, 10065
    - Recruiting
    - Memorial Sloan Kettering Cancer Center
    - Contact:
      
      Mark Awad, Site 0606
  - Westbury, New York, United States, 11590
    - Withdrawn
    - Local Institution - 0339
  - Westbury, New York, United States, 11590
    - Not yet recruiting
    - Local Institution - 0909
    - Contact:
      
      Site 0909
- North Carolina
  - Winston-Salem, North Carolina, United States, 27103
    - Not yet recruiting
    - Local Institution - 0493
    - Contact:
      
      Site 0493
- Ohio
  - Akron, Ohio, United States, 44302
    - Not yet recruiting
    - Local Institution - 0923
    - Contact:
      
      Site 0923
  - Cincinnati, Ohio, United States, 45219
    - Not yet recruiting
    - Local Institution - 0412
    - Contact:
      
      Site 0412
  - Cleveland, Ohio, United States, 44106-5066
    - Not yet recruiting
    - Local Institution - 0359
    - Contact:
      
      Site 0359
  - Cleveland, Ohio, United States, 44195
    - Not yet recruiting
    - Local Institution - 0597
    - Contact:
      
      Site 0597
  - Mayfield Heights, Ohio, United States, 44124
    - Not yet recruiting
    - Local Institution - 0924
    - Contact:
      
      Site 0924
- Oregon
  - Eugene, Oregon, United States, 97401
    - Recruiting
    - Oncology Associates Of Oregon, Pc
    - Contact:
      
      Bo Wang, Site 0895
      
      Phone Number: 541-683-5001
  - Happy Valley, Oregon, United States, 97015
    - Recruiting
    - Northwest Cancer Specialists, P.C.
    - Contact:
      
      Anthony Van Ho, Site 0302
      
      Phone Number: 503-885-5411
- Tennessee
  - Nashville, Tennessee, United States, 37203
    - Recruiting
    - SCRI Oncology Partners
    - Contact:
      
      Melissa Johnson, Site 0240
      
      Phone Number: 615-329-7274
  - Nashville, Tennessee, United States, 37203
    - Not yet recruiting
    - Local Institution - 0480
    - Contact:
      
      Site 0480
- Texas
  - Amarillo, Texas, United States, 79124
    - Recruiting
    - Texas Oncology - Amarillo Cancer Center
    - Contact:
      
      Pankaj Khandelwal, Site 0908
      
      Phone Number: 000-000-0000
  - Austin, Texas, United States, 78731
    - Recruiting
    - Texas Oncology-Austin Central
    - Contact:
      
      James Uyeki, Site 0857
      
      Phone Number: 512-427-9400
  - Denton, Texas, United States, 76210
    - Recruiting
    - Texas Oncology
    - Contact:
      
      Kartik Konduri, Site 0894
      
      Phone Number: 214-370-1000
  - Fort Worth, Texas, United States, 76104
    - Not yet recruiting
    - Local Institution - 0811
    - Contact:
      
      Site 0811
  - Houston, Texas, United States, 77030
    - Not yet recruiting
    - Local Institution - 0596
    - Contact:
      
      Site 0596
  - San Antonio, Texas, United States, 78229
    - Recruiting
    - Texas Oncology - San Antonio Medical Center
    - Contact:
      
      Krishna Alluri, Site 0902
      
      Phone Number: 210-656-7177
  - Tyler, Texas, United States, 75702
    - Recruiting
    - Texas Oncology - Northeast Texas
    - Contact:
      
      Sarah Wang, Site 0899
      
      Phone Number: 903-579-9800
- Virginia
  - Christiansburg, Virginia, United States, 24073
    - Recruiting
    - Blue Ridge Cancer Care
    - Contact:
      
      Jerome Goldschmidt, Site 0133
      
      Phone Number: 540-381-5291
  - Norfolk, Virginia, United States, 23502
    - Recruiting
    - Virginia Oncology Associates
    - Contact:
      
      John Paschold, Site 0250

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

Adult
Older Adult

Accepts Healthy Volunteers

Description

Inclusion Criteria

Participants must have a histologically- or cytologically-confirmed diagnoses of non-small cell lung cancer (NSCLC) with unresectable Stage III disease.
Participants must have received at least 2 cycles of platinum-based concurrent chemoradiotherapy (a total dose of radiation of at least 54 Gy).
Participants must have no progressive disease (PD) following treatment with concurrent chemoradiotherapy (CCRT).
Participants must have an Eastern Cooperative Oncology Group (ECOG) performance status (PS) score of 0 or 1.

Exclusion Criteria

Participants with non-squamous histology must not have documented Epidermal Growth Factor Receptor (EGFR) and anaplastic lymphoma kinase (ALK) rearrangements.
Participants must not have an active autoimmune disease.
Participants must not have significant cardiovascular impairment such as uncontrolled hypertension (despite optimal medical treatment), congestive heart failure, active coronary disease (within 6 months prior to randomization), ventricular arrhythmias, major thrombotic or embolic events or major hemorrhagic events within 6 months prior to randomization, or significant risk of pulmonary hemorrhage.
Participants must not have advanced/clinically significant lung disease (within 6 months prior to randomization) or history of interstitial lung disease (ILD) or pneumonitis requiring treatment with systemic steroids (≥ Grade 2), or current or suspected ILD or pneumonitis.
Participants must not have any prior anticancer therapy (outside of CCRT) for locally advanced Stage III disease.
Other protocol-defined Inclusion/Exclusion criteria apply.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: None (Open Label)

Number of Arms

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Arm A	Drug: Pumitamig Specified dose on specified days Other Names: BMS-986545
Active Comparator: Arm B	Drug: Durvalumab Specified dose on specified days

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Progression-free survival (PFS) by blinded independent central review (BICR) (per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1) Time Frame: Up to 3 years	Up to 3 years

Secondary Outcome Measures

Outcome Measure	Time Frame
Overall survival (OS) Time Frame: Up to approximately 9 years	Up to approximately 9 years
PFS by investigator (per RECIST v1.1) Time Frame: Up to 3 years	Up to 3 years
Objective response (OR) by BICR (per RECIST v1.1) Time Frame: Up to 3 years	Up to 3 years
Disease control rate (DCR) by BICR (per RECIST v1.1) Time Frame: Up to 3 years	Up to 3 years
Duration of response (DOR) by BICR (per RECIST v1.1) Time Frame: Up to 3 years	Up to 3 years
Time to Response (TTR) by BICR (per RECIST v1.1) Time Frame: Up to 3 years	Up to 3 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Bristol-Myers Squibb

Collaborators

BioNTech SE

Investigators

Study Director: Bristol-Myers Squibb, Bristol-Myers Squibb

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 16, 2026

Primary Completion (Estimated)

September 18, 2030

Study Completion (Estimated)

December 31, 2033

Study Registration Dates

First Submitted

January 21, 2026

First Submitted That Met QC Criteria

January 21, 2026

First Posted (Actual)

January 23, 2026

Study Record Updates

Last Update Posted (Actual)

June 3, 2026

Last Update Submitted That Met QC Criteria

June 2, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

CA266-0001

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

BMS will provide access to individual anonymized participant data upon request from qualified researchers, and subject to certain criteria. Additional information regarding Bristol Myer Squibb's data sharing policy and process can be found at https://www.bms.com/researchers-and-partners/clinical-trials-and-research.html

IPD Sharing Time Frame

See Plan Description

IPD Sharing Access Criteria

See Plan Description

IPD Sharing Supporting Information Type

STUDY_PROTOCOL
SAP
CSR

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer

Metastatic Breast Cancer | Locally Advanced Breast Cancer | Unresectable Breast Carcinoma

United States, France, China, United Kingdom, Canada, Georgia, Italy, Turkey (Türkiye), Moldova
BioNTech SE
Bristol-Myers Squibb; BioNTech (Shanghai) Pharmaceuticals Co., Ltd.

Recruiting

A Clinical Trial Testing the Safety of BNT327 (an Investigational Drug) and How Well it Works When Combined With Chemotherapy for People Who Have Not Been Treated Yet for Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma (PDAC)

China
Bristol-Myers Squibb
BioNTech SE

Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204) (ROSETTA GI 204)

Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

United States, United Kingdom, Germany, Spain, Australia, Italy, Japan, France, Romania, Brazil, China, Argentina, South Korea, Poland, Canada, Chile, Colombia, India, Mexico, Turkey (Türkiye)
Bristol-Myers Squibb
BioNTech SE

Recruiting

A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

Hepatocellular Carcinoma (HCC)

United States, Taiwan, Australia, Spain, Germany, France, Italy, United Kingdom, Chile, China, Poland, Singapore, South Korea, Japan
Bristol-Myers Squibb
BioNTech SE

Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Ipilimumab or Cabozantinib in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

Advanced Renal Cell Carcinoma (RCC)

United States, United Kingdom, Switzerland, Japan, Chile, Argentina, Romania, Australia, Brazil, Canada, Colombia, Czechia, Finland, France, Germany, Ireland, Italy, Mexico, South Korea, Spain
BioNTech SE
BioNTech (Shanghai) Pharmaceuticals Co., Ltd.

Recruiting

Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

Non-small Cell Lung Cancer

United States, Spain, United Kingdom, Australia, South Korea, Turkey (Türkiye)
Bristol-Myers Squibb
BioNTech SE

Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Untreated, Unresectable, or Metastatic Colorectal Cancer

United States, Taiwan, Belgium, Canada, Spain, Germany, France, United Kingdom, Italy, Japan, Singapore, Australia, Romania, Czechia, Argentina, Austria, South Korea, Poland, Brazil, Chile, China, India, Netherlands, Sweden, Turkey (Türkiye) and more

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Compared to Durvalumab in Participants With Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy.

Study Overview

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