An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

May 14, 2026 updated by: Novartis Pharmaceuticals

A Single Arm, Multicenter, Open-label Extension (OLE) Trial to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) in Participants Who Completed the Parent Lp(a)HORIZON Trial

This open-label extension study will provide post-trial access to pelacarsen (TQJ230) to participants who have successfully completed the double-blind parent study (CTQJ230A12301).

Study Overview

Status

Recruiting

Conditions

Cardiovascular Disease and Lipoprotein(a)

Intervention / Treatment

Drug: Pelacarsen (TQJ230)

Detailed Description

This study will evaluate long-term safety and tolerability of pelacarsen (TQJ230) 80 mg Once a month (QM) in participants with established cardiovascular disease and elevated Lp(a) who completed the parent study (CTQJ230A12301).

Study Type

Interventional

Enrollment (Estimated)

5700

Phase

Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Name: Novartis Pharmaceuticals
Phone Number: 1-888-669-6682
Email: novartis.email@novartis.com

Study Contact Backup

Name: Novartis Pharmaceuticals
Phone Number: +41613241111

Study Locations

Argentina
- - Buenos Aires, Argentina, C1280AEB
    - Recruiting
    - Novartis Investigative Site
  - Caba, Argentina, C1426
    - Recruiting
    - Novartis Investigative Site
  - Capital Federal, Argentina, C1023AAB
    - Recruiting
    - Novartis Investigative Site
  - Corrientes, Argentina, W3400CDS
    - Recruiting
    - Novartis Investigative Site
  - San Luis, Argentina, D5702JRS
    - Recruiting
    - Novartis Investigative Site
- Buenos Aires
  - CABA, Buenos Aires, Argentina, 1407
    - Recruiting
    - Novartis Investigative Site
  - Caba, Buenos Aires, Argentina, C1119ACN
    - Recruiting
    - Novartis Investigative Site
  - Mar del Plata, Buenos Aires, Argentina, 7600
    - Recruiting
    - Novartis Investigative Site
  - Ramos Mejía, Buenos Aires, Argentina, B1704ETD
    - Recruiting
    - Novartis Investigative Site
- Buenos Aires F.D.
  - CABA, Buenos Aires F.D., Argentina, 1426
    - Recruiting
    - Novartis Investigative Site
- Córdoba Province
  - Córdoba, Córdoba Province, Argentina, 5000
    - Recruiting
    - Novartis Investigative Site
- San Miguel de Tucuman
  - San Miguel de Tucumán, San Miguel de Tucuman, Argentina, 4000
    - Recruiting
    - Novartis Investigative Site
  - San Miguel de Tucumán, San Miguel de Tucuman, Argentina, T4000ICL
    - Recruiting
    - Novartis Investigative Site
- Santa Fe Province
  - Rosario, Santa Fe Province, Argentina, 2000
    - Recruiting
    - Novartis Investigative Site
  - Rosario, Santa Fe Province, Argentina, S200CVD
    - Recruiting
    - Novartis Investigative Site
  - Santa Fe, Santa Fe Province, Argentina, S3000FWO
    - Recruiting
    - Novartis Investigative Site
Australia
- New South Wales
  - Camperdown, New South Wales, Australia, 2050
    - Recruiting
    - Novartis Investigative Site
  - Liverpool, New South Wales, Australia, 2170
    - Recruiting
    - Novartis Investigative Site
- Queensland
  - Chemside, Queensland, Australia, 4032
    - Recruiting
    - Novartis Investigative Site
  - Woolloongabba, Queensland, Australia, 4102
    - Recruiting
    - Novartis Investigative Site
- Victoria
  - Clayton, Victoria, Australia, 3168
    - Recruiting
    - Novartis Investigative Site
- Western Australia
  - Perth, Western Australia, Australia, 6000
    - Recruiting
    - Novartis Investigative Site
Austria
- - Graz, Austria, 8036
    - Recruiting
    - Novartis Investigative Site
  - Innsbruck, Austria, 6020
    - Recruiting
    - Novartis Investigative Site
  - Linz, Austria, 4021
    - Recruiting
    - Novartis Investigative Site
  - Salzburg, Austria, 5020
    - Recruiting
    - Novartis Investigative Site
  - Vienna, Austria, 1090
    - Recruiting
    - Novartis Investigative Site
  - Vienna, Austria, 1210
    - Recruiting
    - Novartis Investigative Site
Belgium
- - Bruges, Belgium, 8000
    - Recruiting
    - Novartis Investigative Site
  - Dendermonde, Belgium, 9200
    - Recruiting
    - Novartis Investigative Site
  - Huy, Belgium, 4500
    - Recruiting
    - Novartis Investigative Site
- Brussels Capital
  - Brussels, Brussels Capital, Belgium, 1070
    - Recruiting
    - Novartis Investigative Site
- Limburg
  - Genk, Limburg, Belgium, 3600
    - Recruiting
    - Novartis Investigative Site
- Oost Vlaanderen
  - Aalst, Oost Vlaanderen, Belgium, 9300
    - Recruiting
    - Novartis Investigative Site
- West-Vlaanderen
  - Kortrijk, West-Vlaanderen, Belgium, 8500
    - Recruiting
    - Novartis Investigative Site
Brazil
- - Rio de Janeiro, Brazil, 20241-180
    - Recruiting
    - Novartis Investigative Site
- Espírito Santo
  - Vitória, Espírito Santo, Brazil, 29055-450
    - Recruiting
    - Novartis Investigative Site
- Estado de Bahia
  - Salvador, Estado de Bahia, Brazil, 40170-130
    - Recruiting
    - Novartis Investigative Site
- Goiás
  - Goiânia, Goiás, Brazil, 74605-020
    - Recruiting
    - Novartis Investigative Site
- Minas Gerais
  - Belo Horizonte, Minas Gerais, Brazil, 30150-270
    - Recruiting
    - Novartis Investigative Site
  - Belo Horizonte, Minas Gerais, Brazil, 30150-320
    - Recruiting
    - Novartis Investigative Site
  - Juiz de Fora, Minas Gerais, Brazil, 36033-318
    - Recruiting
    - Novartis Investigative Site
  - Uberlândia, Minas Gerais, Brazil, 38400 500
    - Recruiting
    - Novartis Investigative Site
- Paraná
  - Curitiba, Paraná, Brazil, 80730-150
    - Recruiting
    - Novartis Investigative Site
- Rio Grande do Sul
  - Canoas, Rio Grande do Sul, Brazil, 92425 900
    - Recruiting
    - Novartis Investigative Site
  - Porto Alegre, Rio Grande do Sul, Brazil, 90880-480
    - Recruiting
    - Novartis Investigative Site
  - Porto Alegre, Rio Grande do Sul, Brazil, 90160-093
    - Recruiting
    - Novartis Investigative Site
- Santa Catarina
  - Blumenau, Santa Catarina, Brazil, 89020-430
    - Recruiting
    - Novartis Investigative Site
- Sergipe
  - Aracaju, Sergipe, Brazil, 49055-530
    - Recruiting
    - Novartis Investigative Site
- São Paulo
  - Campinas, São Paulo, Brazil, 13060 080
    - Recruiting
    - Novartis Investigative Site
  - Campinas, São Paulo, Brazil, 13092133
    - Recruiting
    - Novartis Investigative Site
  - Ribeirão Preto, São Paulo, Brazil, 14026-020
    - Recruiting
    - Novartis Investigative Site
  - Santo André, São Paulo, Brazil, 09090-790
    - Recruiting
    - Novartis Investigative Site
  - Santo André, São Paulo, Brazil, 09060-870
    - Recruiting
    - Novartis Investigative Site
  - Sao Jose Rio Preto, São Paulo, Brazil, 15090 000
    - Recruiting
    - Novartis Investigative Site
  - Sao Jose Rio Preto, São Paulo, Brazil, 15015-750
    - Recruiting
    - Novartis Investigative Site
  - São Paulo, São Paulo, Brazil, 01323 000
    - Recruiting
    - Novartis Investigative Site
  - São Paulo, São Paulo, Brazil, 04005-003
    - Recruiting
    - Novartis Investigative Site
  - São Paulo, São Paulo, Brazil, 04266 010
    - Recruiting
    - Novartis Investigative Site
  - São Paulo, São Paulo, Brazil, 05403-900
    - Recruiting
    - Novartis Investigative Site
Bulgaria
- - Burgas, Bulgaria, 8001
    - Recruiting
    - Novartis Investigative Site
  - Pernik, Bulgaria, 2300
    - Recruiting
    - Novartis Investigative Site
  - Pleven, Bulgaria, 5800
    - Recruiting
    - Novartis Investigative Site
  - Plovdiv, Bulgaria, 4000
    - Recruiting
    - Novartis Investigative Site
  - Rousse, Bulgaria, 7002
    - Recruiting
    - Novartis Investigative Site
  - Sofia, Bulgaria, 1233
    - Recruiting
    - Novartis Investigative Site
Canada
- Ontario
  - Oakville, Ontario, Canada, L6K 3W7
    - Recruiting
    - Novartis Investigative Site
  - Toronto, Ontario, Canada, M9V 4B4
    - Recruiting
    - Novartis Investigative Site
- Quebec
  - Montreal, Quebec, Canada, H4A 3J1
    - Recruiting
    - Novartis Investigative Site
  - Montreal, Quebec, Canada, H1T 1C8
    - Recruiting
    - Novartis Investigative Site
China
- - Beijing, China, 100730
    - Recruiting
    - Novartis Investigative Site
  - Beijing, China, 100050
    - Recruiting
    - Novartis Investigative Site
  - Beijing, China, 100191
    - Recruiting
    - Novartis Investigative Site
  - Shanghai, China, 200025
    - Recruiting
    - Novartis Investigative Site
  - Shanghai, China, 200040
    - Recruiting
    - Novartis Investigative Site
  - Shanghai, China, 200120
    - Recruiting
    - Novartis Investigative Site
  - Shanghai, China, 200065
    - Recruiting
    - Novartis Investigative Site
  - Tianjin, China, 300052
    - Recruiting
    - Novartis Investigative Site
  - Tianjin, China, 030045
    - Recruiting
    - Novartis Investigative Site
  - Tianjin, China, 300121
    - Recruiting
    - Novartis Investigative Site
  - Xiamen, China, 361004
    - Recruiting
    - Novartis Investigative Site
- Beijing Municipality
  - Beijing, Beijing Municipality, China, 100013
    - Recruiting
    - Novartis Investigative Site
- Gansu
  - Lanzhou, Gansu, China, 730030
    - Recruiting
    - Novartis Investigative Site
- Guangdong
  - Foshan, Guangdong, China, 528000
    - Recruiting
    - Novartis Investigative Site
  - Guangzhou, Guangdong, China, 510080
    - Recruiting
    - Novartis Investigative Site
  - Guangzhou, Guangdong, China, 510030
    - Recruiting
    - Novartis Investigative Site
- Heilongjiang
  - Harbin, Heilongjiang, China, 150000
    - Recruiting
    - Novartis Investigative Site
- Hunan
  - Changsha, Hunan, China, 410011
    - Recruiting
    - Novartis Investigative Site
  - Changsha, Hunan, China, 410003
    - Recruiting
    - Novartis Investigative Site
  - Changsha, Hunan, China, 410008
    - Recruiting
    - Novartis Investigative Site
- Inner Mongolia
  - Baotou, Inner Mongolia, China, 014040
    - Recruiting
    - Novartis Investigative Site
- Jiangsu
  - Nanjing, Jiangsu, China, 210009
    - Recruiting
    - Novartis Investigative Site
  - Nanjing, Jiangsu, China, 210029
    - Recruiting
    - Novartis Investigative Site
  - Nanjing, Jiangsu, China, 211166
    - Recruiting
    - Novartis Investigative Site
  - Suzhou, Jiangsu, China, 215004
    - Recruiting
    - Novartis Investigative Site
  - Xuzhou, Jiangsu, China, 221003
    - Recruiting
    - Novartis Investigative Site
- Jilin
  - Changchun, Jilin, China, 130021
    - Recruiting
    - Novartis Investigative Site
- Liaoning
  - Dalian, Liaoning, China, 116011
    - Recruiting
    - Novartis Investigative Site
  - Shenyang, Liaoning, China, 110016
    - Recruiting
    - Novartis Investigative Site
  - Shenyang, Liaoning, China, 110004
    - Recruiting
    - Novartis Investigative Site
- Shandong
  - Jinan, Shandong, China, 250013
    - Recruiting
    - Novartis Investigative Site
- Shanxi
  - Xian, Shanxi, China, 710061
    - Recruiting
    - Novartis Investigative Site
- Sichuan
  - Chengdu, Sichuan, China, 610041
    - Recruiting
    - Novartis Investigative Site
- Xinjiang
  - Ürümqi, Xinjiang, China, 830054
    - Recruiting
    - Novartis Investigative Site
- Zhejiang
  - Hangzhou, Zhejiang, China, 310014
    - Recruiting
    - Novartis Investigative Site
  - Hangzhou, Zhejiang, China, 310016
    - Recruiting
    - Novartis Investigative Site
  - Wenzhou, Zhejiang, China, 325000
    - Recruiting
    - Novartis Investigative Site
Colombia
- - Bogotá, Colombia, 111211
    - Recruiting
    - Novartis Investigative Site
  - Medellín, Colombia, 050037
    - Recruiting
    - Novartis Investigative Site
  - San Gil, Colombia, 684031
    - Recruiting
    - Novartis Investigative Site
- Antioquia
  - Medellín, Antioquia, Colombia, 050001
    - Recruiting
    - Novartis Investigative Site
- Colombia
  - Barranquilla, Colombia, Colombia, 080020
    - Recruiting
    - Novartis Investigative Site
- Santander Department
  - Bucaramanga, Santander Department, Colombia, 681017
    - Recruiting
    - Novartis Investigative Site
- Valle del Cauca Department
  - Cali, Valle del Cauca Department, Colombia, 760032
    - Recruiting
    - Novartis Investigative Site
  - Cali, Valle del Cauca Department, Colombia, 760001
    - Recruiting
    - Novartis Investigative Site
Czechia
- - Brandýs nad Labem, Czechia, 250 01
    - Recruiting
    - Novartis Investigative Site
  - Brno, Czechia, 625 00
    - Recruiting
    - Novartis Investigative Site
  - Brno, Czechia, 602 00
    - Recruiting
    - Novartis Investigative Site
  - Broumov, Czechia, 550 01
    - Recruiting
    - Novartis Investigative Site
  - CZE, Czechia, 110 00
    - Recruiting
    - Novartis Investigative Site
  - Hlučín, Czechia, 748 01
    - Recruiting
    - Novartis Investigative Site
  - Hodonín, Czechia, 695 01
    - Recruiting
    - Novartis Investigative Site
  - Jihlava, Czechia, 586 01
    - Recruiting
    - Novartis Investigative Site
  - Kolín, Czechia, 280 20
    - Recruiting
    - Novartis Investigative Site
  - Liberec, Czechia, 460 01
    - Recruiting
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  - Liberec, Czechia, 460 05
    - Recruiting
    - Novartis Investigative Site
  - Mariánské Lázně, Czechia, 353 01
    - Recruiting
    - Novartis Investigative Site
  - Most, Czechia, 434 01
    - Recruiting
    - Novartis Investigative Site
  - Mělník, Czechia, 276 01
    - Recruiting
    - Novartis Investigative Site
  - Olomouc, Czechia, 779 00
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    - Novartis Investigative Site
  - Ostrava, Czechia, 700 30
    - Recruiting
    - Novartis Investigative Site
  - Pardubice, Czechia, 532 03
    - Recruiting
    - Novartis Investigative Site
  - Polička, Czechia, 57201
    - Recruiting
    - Novartis Investigative Site
  - Prague, Czechia, 128 08
    - Recruiting
    - Novartis Investigative Site
  - Prague, Czechia, 110 00
    - Recruiting
    - Novartis Investigative Site
  - Přerov, Czechia, 751 52
    - Withdrawn
    - Novartis Investigative Site
  - Slaný, Czechia, 274 01
    - Recruiting
    - Novartis Investigative Site
  - Trutnov, Czechia, 460 63
    - Recruiting
    - Novartis Investigative Site
  - Třebíč, Czechia, 674 01
    - Recruiting
    - Novartis Investigative Site
  - Uherské Hradiště, Czechia, 686 01
    - Recruiting
    - Novartis Investigative Site
  - Valašské Meziříčí, Czechia, 75742
    - Recruiting
    - Novartis Investigative Site
  - Zlín, Czechia, 760 01
    - Recruiting
    - Novartis Investigative Site
  - Český Krumlov, Czechia, 381 01
    - Recruiting
    - Novartis Investigative Site
- Chlumec Nad Cidlinou
  - Chlumec nad Cidlinou, Chlumec Nad Cidlinou, Czechia, 503 51
    - Recruiting
    - Novartis Investigative Site
- Czech Republic
  - Kroměříž, Czech Republic, Czechia, 767 55
    - Recruiting
    - Novartis Investigative Site
  - Louny, Czech Republic, Czechia, 440 01
    - Recruiting
    - Novartis Investigative Site
  - Ostrava, Czech Republic, Czechia, 725 27
    - Recruiting
    - Novartis Investigative Site
  - Ústí nad Labem, Czech Republic, Czechia, 400 01
    - Recruiting
    - Novartis Investigative Site
- Zabreh
  - Ostrava, Zabreh, Czechia, 700 30
    - Recruiting
    - Novartis Investigative Site
Denmark
- - Aarhus N, Denmark, 8200
    - Recruiting
    - Novartis Investigative Site
  - Copenhagen, Denmark, DK-2100
    - Recruiting
    - Novartis Investigative Site
  - Esbjerg, Denmark, 6700
    - Recruiting
    - Novartis Investigative Site
  - Gistrup, Denmark, 9260
    - Recruiting
    - Novartis Investigative Site
  - Herlev, Denmark, DK-2730
    - Recruiting
    - Novartis Investigative Site
  - Roskilde, Denmark, 4000
    - Recruiting
    - Novartis Investigative Site
  - Viborg, Denmark, 8800
    - Recruiting
    - Novartis Investigative Site
France
- - Bron, France, 69677
    - Recruiting
    - Novartis Investigative Site
  - Chambray-lès-Tours, France, 37170
    - Recruiting
    - Novartis Investigative Site
  - Grenoble, France, 38043
    - Recruiting
    - Novartis Investigative Site
  - Le Coudray, France, 28630
    - Recruiting
    - Novartis Investigative Site
  - Nantes, France, 44093
    - Recruiting
    - Novartis Investigative Site
  - Paris, France, 75018
    - Recruiting
    - Novartis Investigative Site
  - Toulouse, France, 31054
    - Recruiting
    - Novartis Investigative Site
  - Valenciennes, France, 59300
    - Recruiting
    - Novartis Investigative Site
Germany
- - Aachen, Germany, 52074
    - Recruiting
    - Novartis Investigative Site
  - Bad Homburg, Germany, 61348
    - Recruiting
    - Novartis Investigative Site
  - Bad Krozingen, Germany, 79189
    - Recruiting
    - Novartis Investigative Site
  - Bad Oeynhausen, Germany, 32545
    - Recruiting
    - Novartis Investigative Site
  - Bamberg, Germany, 96049
    - Recruiting
    - Novartis Investigative Site
  - Berlin, Germany, 13353
    - Recruiting
    - Novartis Investigative Site
  - Berlin, Germany, 10787
    - Recruiting
    - Novartis Investigative Site
  - Berlin, Germany, 10367
    - Recruiting
    - Novartis Investigative Site
  - Berlin, Germany, 10789
    - Recruiting
    - Novartis Investigative Site
  - Berlin, Germany, 13347
    - Recruiting
    - Novartis Investigative Site
  - Berlin, Germany, 10559
    - Recruiting
    - Novartis Investigative Site
  - Bielefeld, Germany, 33604
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  - Dessau, Germany, 06846
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  - Dortmund, Germany, 44137
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  - Dresden, Germany, 01307
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  - Dresden, Germany, 01069
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    - Novartis Investigative Site
  - Dresden, Germany, 01277
    - Recruiting
    - Novartis Investigative Site
  - Essen, Germany, 45277
    - Recruiting
    - Novartis Investigative Site
  - Essen, Germany, 45355
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  - Essen, Germany, 45359
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  - Gelnhausen, Germany, 63571
    - Recruiting
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  - Hamburg, Germany, 22041
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  - Hamburg, Germany, 22607
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  - Kassel, Germany, 34121
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  - Lüneburg, Germany, 21339
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  - Magdeburg, Germany, 39120
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  - Mannheim, Germany, 68165
    - Recruiting
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  - Meissen, Germany, 01662
    - Recruiting
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  - München, Germany, 80636
    - Recruiting
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  - Münster, Germany, 48149
    - Recruiting
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  - Potsdam, Germany, 14471
    - Recruiting
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  - Rüdersdorf, Germany, 15562
    - Recruiting
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  - Ulm, Germany, 89077
    - Recruiting
    - Novartis Investigative Site
  - Warendorf, Germany, 48231
    - Recruiting
    - Novartis Investigative Site
- Baden-Wurttemberg
  - Mannheim, Baden-Wurttemberg, Germany, 68305
    - Recruiting
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- Bavaria
  - Muehldorf Am Inn, Bavaria, Germany, 84453
    - Recruiting
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  - Munich, Bavaria, Germany, 81377
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    - Novartis Investigative Site
  - Weiden in Der Oberpfalz, Bavaria, Germany, 92637
    - Recruiting
    - Novartis Investigative Site
- Hesse
  - Frankfurt am Main, Hesse, Germany, 60590
    - Recruiting
    - Novartis Investigative Site
  - Frankfurt am Main, Hesse, Germany, 60594
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    - Novartis Investigative Site
- Lower Saxony
  - Hanover, Lower Saxony, Germany, 30159
    - Recruiting
    - Novartis Investigative Site
- North Rhine-Westphalia
  - Cologne, North Rhine-Westphalia, Germany, 50937
    - Recruiting
    - Novartis Investigative Site
  - Cologne, North Rhine-Westphalia, Germany, 50733
    - Recruiting
    - Novartis Investigative Site
  - Essen, North Rhine-Westphalia, Germany, 45355
    - Recruiting
    - Novartis Investigative Site
  - Löhne, North Rhine-Westphalia, Germany, 32584
    - Recruiting
    - Novartis Investigative Site
- Saarland
  - Saint Ingbert, Saarland, Germany, 66386
    - Recruiting
    - Novartis Investigative Site
- Saxony
  - Chemnitz, Saxony, Germany, 09113
    - Recruiting
    - Novartis Investigative Site
  - Dresden, Saxony, Germany, 01307
    - Recruiting
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  - Dresden, Saxony, Germany, 01099
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    - Novartis Investigative Site
  - Leipzig, Saxony, Germany, 04103
    - Recruiting
    - Novartis Investigative Site
- Saxony-Anhalt
  - Wittenberg, Saxony-Anhalt, Germany, 06886
    - Recruiting
    - Novartis Investigative Site
- Thuringia
  - Jena, Thuringia, Germany, 07740
    - Recruiting
    - Novartis Investigative Site
Greece
- - Athens, Greece, 115 27
    - Recruiting
    - Novartis Investigative Site
  - Athens, Greece, 115 21
    - Recruiting
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  - Athens, Greece, 142 33
    - Recruiting
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  - Ioannina, Greece, 455 00
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    - Novartis Investigative Site
  - Larissa, Greece, 411 10
    - Recruiting
    - Novartis Investigative Site
  - Thessaloniki, Greece, 54636
    - Recruiting
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Hong Kong
- - Hong Kong, Hong Kong, 999077
    - Recruiting
    - Novartis Investigative Site
- Hong Kong
  - Hong Kong, Hong Kong, Hong Kong, 999077
    - Recruiting
    - Novartis Investigative Site
Hungary
- - Baja, Hungary, 6500
    - Recruiting
    - Novartis Investigative Site
  - Budapest, Hungary, H-1083
    - Recruiting
    - Novartis Investigative Site
  - Budapest, Hungary, H-1145
    - Recruiting
    - Novartis Investigative Site
  - Budapest, Hungary, 1211
    - Recruiting
    - Novartis Investigative Site
  - Szeged, Hungary, 6725
    - Recruiting
    - Novartis Investigative Site
- Hajdu Bihar Megye
  - Debrecen, Hajdu Bihar Megye, Hungary, 4032
    - Recruiting
    - Novartis Investigative Site
India
- - New Delhi, India, 110025
    - Recruiting
    - Novartis Investigative Site
- Andhra Pradesh
  - Guntur, Andhra Pradesh, India, 522001
    - Recruiting
    - Novartis Investigative Site
- Gujarat
  - Ahmedabad, Gujarat, India, 380054
    - Recruiting
    - Novartis Investigative Site
  - Ahmedabad, Gujarat, India, 380060
    - Recruiting
    - Novartis Investigative Site
  - Vadodara, Gujarat, India, 390022
    - Recruiting
    - Novartis Investigative Site
- Karnataka
  - Belagavi, Karnataka, India, 590010
    - Recruiting
    - Novartis Investigative Site
  - Mangalore, Karnataka, India, 575018
    - Recruiting
    - Novartis Investigative Site
  - Manipal, Karnataka, India, 576104
    - Recruiting
    - Novartis Investigative Site
  - Mysore, Karnataka, India, 570015
    - Recruiting
    - Novartis Investigative Site
- Kerala
  - Kochi, Kerala, India, 682041
    - Recruiting
    - Novartis Investigative Site
  - Kochi, Kerala, India, 682018
    - Recruiting
    - Novartis Investigative Site
  - Kochi, Kerala, India, 682027
    - Recruiting
    - Novartis Investigative Site
- Maharashtra
  - Nagpur, Maharashtra, India, 440012
    - Recruiting
    - Novartis Investigative Site
  - Nagpur, Maharashtra, India, 440008
    - Recruiting
    - Novartis Investigative Site
  - Nagpur, Maharashtra, India, 440033
    - Recruiting
    - Novartis Investigative Site
  - Nagpur, Maharashtra, India, 440025
    - Recruiting
    - Novartis Investigative Site
  - Nashik, Maharashtra, India, 422005
    - Recruiting
    - Novartis Investigative Site
  - Pune, Maharashtra, India, 411004
    - Recruiting
    - Novartis Investigative Site
  - Pune, Maharashtra, India, 411045
    - Recruiting
    - Novartis Investigative Site
  - Pune, Maharashtra, India, 411028
    - Recruiting
    - Novartis Investigative Site
- National Capital Territory of Delhi
  - New Delhi, National Capital Territory of Delhi, India, 110060
    - Recruiting
    - Novartis Investigative Site
  - New Delhi, National Capital Territory of Delhi, India, 110075
    - Recruiting
    - Novartis Investigative Site
- Rajasthan
  - Bikaner, Rajasthan, India, 334003
    - Recruiting
    - Novartis Investigative Site
- Tamil Nadu
  - Chennai, Tamil Nadu, India, 600006
    - Recruiting
    - Novartis Investigative Site
  - Coimbatore, Tamil Nadu, India, 641037
    - Recruiting
    - Novartis Investigative Site
  - Coimbatore, Tamil Nadu, India, 641009
    - Recruiting
    - Novartis Investigative Site
- Telangana
  - Hyderabad, Telangana, India, 500034
    - Recruiting
    - Novartis Investigative Site
  - Hyderabad, Telangana, India, 500082
    - Recruiting
    - Novartis Investigative Site
  - Secunderabad, Telangana, India, 500003
    - Recruiting
    - Novartis Investigative Site
- Uttar Pradesh
  - Ghaziabad, Uttar Pradesh, India, 201012
    - Recruiting
    - Novartis Investigative Site
  - Lucknow, Uttar Pradesh, India, 226003
    - Recruiting
    - Novartis Investigative Site
- Uttarakhand
  - Dehradun, Uttarakhand, India, 248001
    - Recruiting
    - Novartis Investigative Site
Israel
- - Beersheba, Israel, 8457108
    - Recruiting
    - Novartis Investigative Site
  - Haifa, Israel, 3104802
    - Recruiting
    - Novartis Investigative Site
  - Haifa, Israel, 3436212
    - Recruiting
    - Novartis Investigative Site
  - Jerusalem, Israel, 9112001
    - Recruiting
    - Novartis Investigative Site
  - Petah Tikva, Israel, 4941492
    - Recruiting
    - Novartis Investigative Site
  - Ramat Gan, Israel, 5265601
    - Recruiting
    - Novartis Investigative Site
Italy
- - Naples, Italy, 80131
    - Recruiting
    - Novartis Investigative Site
- AN
  - Ancona, AN, Italy, 60128
    - Recruiting
    - Novartis Investigative Site
- BG
  - Bergamo, BG, Italy, 24127
    - Recruiting
    - Novartis Investigative Site
- BO
  - Bologna, BO, Italy, 40138
    - Recruiting
    - Novartis Investigative Site
- BS
  - Brescia, BS, Italy, 25123
    - Recruiting
    - Novartis Investigative Site
- FE
  - Cona, FE, Italy, 44124
    - Recruiting
    - Novartis Investigative Site
- FI
  - Florence, FI, Italy, 50134
    - Recruiting
    - Novartis Investigative Site
- IS
  - Pozzilli, IS, Italy, 86077
    - Recruiting
    - Novartis Investigative Site
- MI
  - Milan, MI, Italy, 20132
    - Recruiting
    - Novartis Investigative Site
  - Milan, MI, Italy, 20162
    - Recruiting
    - Novartis Investigative Site
  - Milan, MI, Italy, 20138
    - Recruiting
    - Novartis Investigative Site
  - Milan, MI, Italy, 20149
    - Recruiting
    - Novartis Investigative Site
  - Rozzano, MI, Italy, 20089
    - Recruiting
    - Novartis Investigative Site
- PA
  - Palermo, PA, Italy, 90127
    - Recruiting
    - Novartis Investigative Site
- PG
  - Perugia, PG, Italy, 06129
    - Recruiting
    - Novartis Investigative Site
- PI
  - Pisa, PI, Italy, 56126
    - Recruiting
    - Novartis Investigative Site
  - Pisa, PI, Italy, 56124
    - Recruiting
    - Novartis Investigative Site
- RM
  - Roma, RM, Italy, 00189
    - Recruiting
    - Novartis Investigative Site
  - Roma, RM, Italy, 00161
    - Recruiting
    - Novartis Investigative Site
- VA
  - Varese, VA, Italy, 21100
    - Recruiting
    - Novartis Investigative Site
Japan
- Aichi-ken
  - Seto, Aichi-ken, Japan, 4898642
    - Recruiting
    - Novartis Investigative Site
- Chiba
  - Funabashi, Chiba, Japan, 273-8588
    - Recruiting
    - Novartis Investigative Site
  - Matsudo, Chiba, Japan, 270-2251
    - Recruiting
    - Novartis Investigative Site
- Fukuoka
  - Kitakyushu, Fukuoka, Japan, 8028555
    - Recruiting
    - Novartis Investigative Site
- Hiroshima
  - Kure, Hiroshima, Japan, 737-0023
    - Recruiting
    - Novartis Investigative Site
- Kanagawa
  - Kawasaki, Kanagawa, Japan, 2120021
    - Recruiting
    - Novartis Investigative Site
- Miyazaki
  - Miyhazaki, Miyazaki, Japan, 8802102
    - Recruiting
    - Novartis Investigative Site
- Shiga
  - Ōmihachiman, Shiga, Japan, 523-0082
    - Recruiting
    - Novartis Investigative Site
- Tokyo
  - Bunkyo Ku, Tokyo, Japan, 1138431
    - Recruiting
    - Novartis Investigative Site
  - Chuo-ku, Tokyo, Japan, 1030027
    - Recruiting
    - Novartis Investigative Site
  - Itabashi-ku, Tokyo, Japan, 1738610
    - Recruiting
    - Novartis Investigative Site
Netherlands
- - Amersfoort, Netherlands, 3813 TZ
    - Recruiting
    - Novartis Investigative Site
  - Gouda, Netherlands, 2803 HH
    - Recruiting
    - Novartis Investigative Site
  - Hardenberg, Netherlands, 7770 SE
    - Recruiting
    - Novartis Investigative Site
  - Utrecht, Netherlands, 3584 CX
    - Recruiting
    - Novartis Investigative Site
  - Venlo, Netherlands, 5912 BL
    - Recruiting
    - Novartis Investigative Site
- Gelderland
  - Apeldoorn, Gelderland, Netherlands, 7334 DZ
    - Recruiting
    - Novartis Investigative Site
  - Arnhem, Gelderland, Netherlands, 6815 AD
    - Recruiting
    - Novartis Investigative Site
  - Nijmegen, Gelderland, Netherlands, 6500HB
    - Recruiting
    - Novartis Investigative Site
  - Tiel, Gelderland, Netherlands, 4002 WP
    - Recruiting
    - Novartis Investigative Site
- Limburg
  - Heerlen, Limburg, Netherlands, 6419 PC
    - Recruiting
    - Novartis Investigative Site
- North Brabant
  - Tilburg, North Brabant, Netherlands, 5042 AD
    - Recruiting
    - Novartis Investigative Site
- North Holland
  - Alkmaar, North Holland, Netherlands, 1815 JD
    - Recruiting
    - Novartis Investigative Site
  - Amsterdam, North Holland, Netherlands, 1105 AZ
    - Recruiting
    - Novartis Investigative Site
  - Amsterdam, North Holland, Netherlands, 1090 HM
    - Recruiting
    - Novartis Investigative Site
  - Heemstede, North Holland, Netherlands, 2035 RC
    - Recruiting
    - Novartis Investigative Site
- Overijssel
  - Deventer, Overijssel, Netherlands, 7416 SE
    - Recruiting
    - Novartis Investigative Site
- Provincie Friesland
  - Sneek, Provincie Friesland, Netherlands, 8601 ZK
    - Recruiting
    - Novartis Investigative Site
- Provincie Groningen
  - Groningen, Provincie Groningen, Netherlands, 9728 NZ
    - Recruiting
    - Novartis Investigative Site
- South Holland
  - Leiden, South Holland, Netherlands, 2333 ZA
    - Recruiting
    - Novartis Investigative Site
  - Leiderdorp, South Holland, Netherlands, 2353 GA
    - Recruiting
    - Novartis Investigative Site
  - The Hague, South Holland, Netherlands, 2545 AA
    - Recruiting
    - Novartis Investigative Site
Poland
- - Bielsko-Biala, Poland, 43-316
    - Recruiting
    - Novartis Investigative Site
  - Chrzanów, Poland, 32-500
    - Recruiting
    - Novartis Investigative Site
  - Gdansk, Poland, 80-214
    - Recruiting
    - Novartis Investigative Site
  - Gdynia, Poland, 81-157
    - Recruiting
    - Novartis Investigative Site
  - Lodz, Poland, 93-338
    - Recruiting
    - Novartis Investigative Site
  - Lodz, Poland, 91 347
    - Recruiting
    - Novartis Investigative Site
  - Tarnów, Poland, 33-100
    - Recruiting
    - Novartis Investigative Site
Portugal
- - Coimbra, Portugal, 3004-561
    - Recruiting
    - Novartis Investigative Site
  - Guimarães, Portugal, 4835-044
    - Recruiting
    - Novartis Investigative Site
  - Setúbal, Portugal, 2910-549
    - Recruiting
    - Novartis Investigative Site
Puerto Rico
- - Ponce, Puerto Rico, 00717-1322
    - Recruiting
    - Research and Cardiovascular Corp
    - Contact:
      
      Maria E Diago
      
      Phone Number: +1 787 259 0526
      
      Email: diago_research@yahoo.com
    - Principal Investigator:
      
      Jose B Vazquez-Tanus
Romania
- - Bucharest, Romania, 050098
    - Recruiting
    - Novartis Investigative Site
  - Bucharest, Romania, 010192
    - Recruiting
    - Novartis Investigative Site
- Buzău
  - Buzău, Buzău, Romania, 120133
    - Recruiting
    - Novartis Investigative Site
- Dolj
  - Craiova, Dolj, Romania, 200513
    - Recruiting
    - Novartis Investigative Site
- Maramureş
  - Baia Mare, Maramureş, Romania, 430123
    - Recruiting
    - Novartis Investigative Site
  - Baia Mare, Maramureş, Romania, 430222
    - Recruiting
    - Novartis Investigative Site
Russia
- - Chelyabinsk, Russia, 454047
    - Recruiting
    - Novartis Investigative Site
  - Ivanovo, Russia, 153012
    - Recruiting
    - Novartis Investigative Site
  - Izhevsk, Russia, 426061
    - Recruiting
    - Novartis Investigative Site
  - Kemerovo, Russia, 650002
    - Recruiting
    - Novartis Investigative Site
  - Kirov, Russia, 610035
    - Recruiting
    - Novartis Investigative Site
  - Krasnodar, Russia, 350086
    - Recruiting
    - Novartis Investigative Site
  - Moscow, Russia, 117198
    - Recruiting
    - Novartis Investigative Site
  - Moscow, Russia, 101990
    - Recruiting
    - Novartis Investigative Site
  - Moscow, Russia, 121552
    - Recruiting
    - Novartis Investigative Site
  - Moscow, Russia, 127473
    - Recruiting
    - Novartis Investigative Site
  - Moscow, Russia, 141060
    - Recruiting
    - Novartis Investigative Site
  - Novosibirsk, Russia, 630090
    - Recruiting
    - Novartis Investigative Site
  - Perm, Russia, 614097
    - Recruiting
    - Novartis Investigative Site
  - Rostov-on-Don, Russia, 344022
    - Recruiting
    - Novartis Investigative Site
  - Ryazan, Russia, 390039
    - Recruiting
    - Novartis Investigative Site
  - Saint Petersburg, Russia, 197341
    - Recruiting
    - Novartis Investigative Site
  - Saint Petersburg, Russia, 191015
    - Recruiting
    - Novartis Investigative Site
  - Saint Petersburg, Russia, 194354
    - Recruiting
    - Novartis Investigative Site
  - Saint Petersburg, Russia, 195197
    - Recruiting
    - Novartis Investigative Site
  - Saint Petersburg, Russia, 196143
    - Recruiting
    - Novartis Investigative Site
  - Saint Petersburg, Russia, 199178
    - Recruiting
    - Novartis Investigative Site
  - Samara, Russia, 443070
    - Recruiting
    - Novartis Investigative Site
  - Saratov, Russia, 410028
    - Recruiting
    - Novartis Investigative Site
  - Saratov, Russia, 410012
    - Recruiting
    - Novartis Investigative Site
  - Sochy, Russia, 354002
    - Recruiting
    - Novartis Investigative Site
  - Tomsk, Russia, 634009
    - Recruiting
    - Novartis Investigative Site
  - Ulyanovsk, Russia, 432063
    - Recruiting
    - Novartis Investigative Site
  - Vsevolozhsk, Russia, 188643
    - Recruiting
    - Novartis Investigative Site
  - Yaroslavl, Russia, 150062
    - Recruiting
    - Novartis Investigative Site
  - Yekaterinburg, Russia, 620028
    - Recruiting
    - Novartis Investigative Site
  - Yekaterinburg, Russia, 620137
    - Recruiting
    - Novartis Investigative Site
  - Yekaterinburg, Russia, 620144
    - Recruiting
    - Novartis Investigative Site
- Russia
  - Saint Petersburg, Russia, Russia, 198328
    - Recruiting
    - Novartis Investigative Site
Slovakia
- - Bardejov, Slovakia, 085 01
    - Recruiting
    - Novartis Investigative Site
  - Bratislava, Slovakia, 833 48
    - Recruiting
    - Novartis Investigative Site
  - Bratislava, Slovakia, 833 05
    - Recruiting
    - Novartis Investigative Site
  - Bratislava, Slovakia, 821 07
    - Recruiting
    - Novartis Investigative Site
  - Bratislava, Slovakia, 851 07
    - Recruiting
    - Novartis Investigative Site
  - Handlová, Slovakia, 972 51
    - Recruiting
    - Novartis Investigative Site
  - Komárno, Slovakia, 945 01
    - Recruiting
    - Novartis Investigative Site
  - Komárno, Slovakia, 945 05
    - Recruiting
    - Novartis Investigative Site
  - Košice, Slovakia, 040 01
    - Recruiting
    - Novartis Investigative Site
  - Lučenec, Slovakia, 984 01
    - Recruiting
    - Novartis Investigative Site
  - Nitra, Slovakia, 949 01
    - Recruiting
    - Novartis Investigative Site
  - Nitra, Slovakia, 950 01
    - Recruiting
    - Novartis Investigative Site
  - Nitra, Slovakia, 949 11
    - Recruiting
    - Novartis Investigative Site
  - Nové Zámky, Slovakia, 940 01
    - Recruiting
    - Novartis Investigative Site
  - Piešťany, Slovakia, 921 01
    - Recruiting
    - Novartis Investigative Site
  - Považská Bystrica, Slovakia, 017 01
    - Recruiting
    - Novartis Investigative Site
  - Prešov, Slovakia, 080 01
    - Recruiting
    - Novartis Investigative Site
  - Rimavská Sobota, Slovakia, 979 01
    - Recruiting
    - Novartis Investigative Site
  - Svidník, Slovakia, 089 01
    - Recruiting
    - Novartis Investigative Site
- Slovakia
  - Trnava, Slovakia, Slovakia, 917 02
    - Recruiting
    - Novartis Investigative Site
South Korea
- - Busan, South Korea, 49201
    - Recruiting
    - Novartis Investigative Site
  - Gwangju, South Korea, 61469
    - Recruiting
    - Novartis Investigative Site
  - Seoul, South Korea, 06591
    - Recruiting
    - Novartis Investigative Site
  - Seoul, South Korea, 03181
    - Recruiting
    - Novartis Investigative Site
- Dalseo gu
  - Daegu, Dalseo gu, South Korea, 42602
    - Recruiting
    - Novartis Investigative Site
- Gangwon-do
  - Wŏnju, Gangwon-do, South Korea, 26426
    - Recruiting
    - Novartis Investigative Site
- Gyeonggi-do
  - Bundang Gu, Gyeonggi-do, South Korea, 13620
    - Recruiting
    - Novartis Investigative Site
  - Suwon, Gyeonggi-do, South Korea, 16499
    - Recruiting
    - Novartis Investigative Site
- Korea
  - Incheon, Korea, South Korea, 405 760
    - Recruiting
    - Novartis Investigative Site
  - Seoul, Korea, South Korea, 02841
    - Recruiting
    - Novartis Investigative Site
- Seoul
  - Seoul, Seoul, South Korea, 03080
    - Recruiting
    - Novartis Investigative Site
Spain
- - A Coruña, Spain, 15001
    - Recruiting
    - Novartis Investigative Site
  - Barcelona, Spain, 08025
    - Recruiting
    - Novartis Investigative Site
  - Barcelona, Spain, 08036
    - Recruiting
    - Novartis Investigative Site
  - Córdoba, Spain, 14004
    - Recruiting
    - Novartis Investigative Site
  - Huelva, Spain, 21080
    - Recruiting
    - Novartis Investigative Site
  - Madrid, Spain, 28041
    - Recruiting
    - Novartis Investigative Site
  - Madrid, Spain, 28040
    - Recruiting
    - Novartis Investigative Site
  - Málaga, Spain, 29010
    - Recruiting
    - Novartis Investigative Site
  - Seville, Spain, 41013
    - Recruiting
    - Novartis Investigative Site
  - Seville, Spain, 41009
    - Recruiting
    - Novartis Investigative Site
  - Zaragoza, Spain, 50009
    - Recruiting
    - Novartis Investigative Site
- A Coruna
  - Santiago Compostela, A Coruna, Spain, 15706
    - Recruiting
    - Novartis Investigative Site
- Andalusia
  - Seville, Andalusia, Spain, 41014
    - Recruiting
    - Novartis Investigative Site
- Barcelona
  - Badalona, Barcelona, Spain, 08916
    - Recruiting
    - Novartis Investigative Site
  - L'Hospitalet de Llobregat, Barcelona, Spain, 08907
    - Recruiting
    - Novartis Investigative Site
- Cantabria
  - Santander, Cantabria, Spain, 39008
    - Recruiting
    - Novartis Investigative Site
- Extremadura
  - Cáceres, Extremadura, Spain, 10003
    - Recruiting
    - Novartis Investigative Site
Switzerland
- - Basel, Switzerland, 4031
    - Recruiting
    - Novartis Investigative Site
  - Bern, Switzerland, 3010
    - Recruiting
    - Novartis Investigative Site
  - Geneva, Switzerland, 1211
    - Recruiting
    - Novartis Investigative Site
  - Lausanne, Switzerland, 1010
    - Recruiting
    - Novartis Investigative Site
  - Liestal, Switzerland, 4410
    - Recruiting
    - Novartis Investigative Site
  - Zurich, Switzerland, 8091
    - Recruiting
    - Novartis Investigative Site
Taiwan
- - Hsinchu, Taiwan, 30069
    - Recruiting
    - Novartis Investigative Site
  - Kaohsiung City, Taiwan, 83301
    - Recruiting
    - Novartis Investigative Site
  - Kaohsiung City, Taiwan, 80756
    - Recruiting
    - Novartis Investigative Site
  - Keelung, Taiwan, 20401
    - Recruiting
    - Novartis Investigative Site
  - Tainan, Taiwan, 71004
    - Recruiting
    - Novartis Investigative Site
  - Taipei, Taiwan, 11217
    - Recruiting
    - Novartis Investigative Site
  - Taoyuan, Taiwan, 33305
    - Recruiting
    - Novartis Investigative Site
  - Yilan, Taiwan, 26058
    - Recruiting
    - Novartis Investigative Site
- Taiwan ROC
  - Taichung, Taiwan ROC, Taiwan, 40201
    - Recruiting
    - Novartis Investigative Site
Turkey (Türkiye)
- - Izmir, Turkey (Türkiye), 35100
    - Recruiting
    - Novartis Investigative Site
- Balcova
  - Izmir, Balcova, Turkey (Türkiye), 35340
    - Recruiting
    - Novartis Investigative Site
- Bilkent-Cankaya
  - Ankara, Bilkent-Cankaya, Turkey (Türkiye), 06800
    - Recruiting
    - Novartis Investigative Site
- Fatih
  - Istanbul, Fatih, Turkey (Türkiye), 34098
    - Recruiting
    - Novartis Investigative Site
- Kadikoy
  - Istanbul, Kadikoy, Turkey (Türkiye), 34668
    - Recruiting
    - Novartis Investigative Site
- Odunpazari
  - Eskişehir, Odunpazari, Turkey (Türkiye), 26040
    - Recruiting
    - Novartis Investigative Site
- Samsun
  - Samsun, Samsun, Turkey (Türkiye), 55080
    - Recruiting
    - Novartis Investigative Site
- Yenisehir
  - Mersin, Yenisehir, Turkey (Türkiye), 33110
    - Recruiting
    - Novartis Investigative Site
United Kingdom
- - Bristol, United Kingdom, BS2 8HW
    - Recruiting
    - Novartis Investigative Site
  - Chesterfield, United Kingdom, S40 4AA
    - Recruiting
    - Novartis Investigative Site
  - Edinburgh, United Kingdom, EH16 4SA
    - Recruiting
    - Novartis Investigative Site
  - Glasgow, United Kingdom, G20 7BE
    - Recruiting
    - Novartis Investigative Site
  - London, United Kingdom, W12 0HS
    - Recruiting
    - Novartis Investigative Site
  - Londonderry, United Kingdom, BT47 6SB
    - Recruiting
    - Novartis Investigative Site
  - Middlesbrough, United Kingdom, TS4 3BW
    - Recruiting
    - Novartis Investigative Site
  - Newport, United Kingdom, NP20 2UB
    - Recruiting
    - Novartis Investigative Site
  - Norwich, United Kingdom, NR4 7UY
    - Recruiting
    - Novartis Investigative Site
  - Sheffield, United Kingdom, S5 7AU
    - Recruiting
    - Novartis Investigative Site
  - Tyne and Wear, United Kingdom, NE29 8NH
    - Recruiting
    - Novartis Investigative Site
  - Wiltshire, United Kingdom, SN15 2SB
    - Recruiting
    - Novartis Investigative Site
  - Wrexham, United Kingdom, LL13 7TD
    - Recruiting
    - Novartis Investigative Site
- Dorset
  - Dorchester, Dorset, United Kingdom, DT1 2JY
    - Recruiting
    - Novartis Investigative Site
- GBR
  - London, GBR, United Kingdom, EC1M 6BQ
    - Recruiting
    - Novartis Investigative Site
- Greater London
  - London, Greater London, United Kingdom, EN3 4GS
    - Recruiting
    - Novartis Investigative Site
- Lancashire
  - Preston, Lancashire, United Kingdom, PR2 9QB
    - Recruiting
    - Novartis Investigative Site
- Middlesex
  - Harrow, Middlesex, United Kingdom, HA1 3UJ
    - Recruiting
    - Novartis Investigative Site
- North Manchester
  - Rochdale, North Manchester, United Kingdom, OL11 4AU
    - Recruiting
    - Novartis Investigative Site
- Nothern Ireland
  - Portadown, Nothern Ireland, United Kingdom, BT63 5QQ
    - Recruiting
    - Novartis Investigative Site
- Surrey
  - Chertsey, Surrey, United Kingdom, KT16 0PZ
    - Recruiting
    - Novartis Investigative Site
- Tyne and Wear
  - Newcastle upon Tyne, Tyne and Wear, United Kingdom, NE7 7DN
    - Recruiting
    - Novartis Investigative Site
  - Sunderland, Tyne and Wear, United Kingdom, SR4 7TP
    - Recruiting
    - Novartis Investigative Site
- Wales
  - Cardiff, Wales, United Kingdom, CF5 4AD
    - Recruiting
    - Novartis Investigative Site
- West Sussex
  - Chichester, West Sussex, United Kingdom, PO19 6SE
    - Recruiting
    - Novartis Investigative Site
United States
- Alabama
  - Andalusia, Alabama, United States, 36420
    - Recruiting
    - SEC Clinical Research LLC
    - Principal Investigator:
      
      Andreas Muench
    - Contact:
      
      Lauren Williams
      
      Phone Number: +1 334 699 1631
      
      Email: lwilliams@secclinicalresearch.com
  - Huntsville, Alabama, United States, 35801
    - Recruiting
    - Heart Center Research LLC
    - Principal Investigator:
      
      Vernon R Hunter
    - Contact:
      
      Melesa Lamb
      
      Phone Number: +1 256 519 8255
      
      Email: mlamb@theheartcenter.md
  - Mobile, Alabama, United States, 36608
    - Recruiting
    - Mobile Heart Specialists
    - Principal Investigator:
      
      Christopher S Brown
    - Contact:
      
      Candace Jenkins
      
      Phone Number: +1 251 433 4700
      
      Email: cjenkins@mobheart.com
- Arizona
  - Gilbert, Arizona, United States, 85297
    - Recruiting
    - Mercy Gilbert Medical Center
    - Principal Investigator:
      
      Nabil Dib
    - Contact:
      
      Chanel Tate
      
      Phone Number: +1 480 728 9978
      
      Email: chanel.tate@commonspirit.org
  - Sun City West, Arizona, United States, 85375
    - Recruiting
    - Clinical Research Inst of Arizona
    - Principal Investigator:
      
      Jalal Abbas
    - Contact:
      
      Georgina Lopez-Wood
      
      Phone Number: +1 623 223 1580
      
      Email: glopezwood@criofaz.com
  - Tucson, Arizona, United States, 85745
    - Recruiting
    - Eclipse Clinical Research
    - Principal Investigator:
      
      Eve Shapiro
    - Contact:
      
      Felice J Anderson
      
      Phone Number: +1 520 647 9926
      
      Email: felice@eclipsecr.com
- California
  - Beverly Hills, California, United States, 90211
    - Recruiting
    - National Heart Institute
    - Principal Investigator:
      
      Norman Lepor
    - Contact:
      
      Nayeli Aguillon
      
      Phone Number: +1 301 289 5221
      
      Email: naguillon@nationalheartinstitute.org
  - Beverly Hills, California, United States, 90210
    - Recruiting
    - Cardiovascular Res Found
    - Principal Investigator:
      
      Ronald P Karlsberg
    - Contact:
      
      Monalisa Nzenwa
      
      Phone Number: +1 310 278 3400
      
      Email: MonaLisa.Nzenwa@cvmg.com
  - Covina, California, United States, 91723
    - Recruiting
    - Valley Clinical Trials Inc
    - Principal Investigator:
      
      Masoud Azizad
    - Contact:
      
      Sarita Garcia
      
      Email: sgarcia@flourishresearch.com
  - Los Angeles, California, United States, 90033
    - Recruiting
    - Keck Medical Center USC
    - Principal Investigator:
      
      Parveen Garg
    - Contact:
      
      Jasbeth Almanza
      
      Email: jasbeth.almanza@med.usc.edu
  - San Francisco, California, United States, 94115
    - Recruiting
    - UCSF
    - Principal Investigator:
      
      Eveline O Stock
    - Contact:
      
      Liliann Zou
      
      Phone Number: +1 415 514 0992
      
      Email: liliann.zou@ucsf.edu
  - Santa Ana, California, United States, 92704
    - Recruiting
    - Helping Hands Medical Associates INC
    - Principal Investigator:
      
      Alan Charles Schwartz
    - Contact:
      
      Maggie Romero
      
      Phone Number: +1 714 662 2900
      
      Email: hhma500@yahoo.com
  - Stockton, California, United States, 95204
    - Recruiting
    - Manshadi Heart Institute
    - Contact:
      
      Delaina Sanguinetti
      
      Email: d.sanguinetti@drmanshadi.com
    - Principal Investigator:
      
      Ramin Manshadi
  - West Hills, California, United States, 91307
    - Recruiting
    - Interv Cardiology Med Grp
    - Principal Investigator:
      
      Farhad Rafii
    - Contact:
      
      Michael Fam
      
      Phone Number: +1 818 235 7104
      
      Email: mfam@elegantrd.com
- Connecticut
  - Hartford, Connecticut, United States, 06102
    - Recruiting
    - Hartford Hospital
    - Principal Investigator:
      
      ANTONIO FERNANDEZ
    - Contact:
      
      Keelyn Kotecki
      
      Phone Number: +1 860 545 2882
      
      Email: keelyn.kotecki@hhchealth.org
  - Waterbury, Connecticut, United States, 06708
    - Recruiting
    - Chase Medical Research LLC
    - Contact:
      
      La Tonya Washington
      
      Phone Number: +1 203 232 3749
      
      Email: lwashington@chasemr.com
    - Principal Investigator:
      
      Ashish Adlakha
- Florida
  - Boca Raton, Florida, United States, 33434
    - Recruiting
    - Excel Medical Clinical Trials LLC
    - Principal Investigator:
      
      Rasha Youssef
    - Contact:
      
      Joseph Ramsey
      
      Phone Number: +1 561 756 8206
      
      Email: jramsey@flourishresearch.com
  - Brandon, Florida, United States, 33511
    - Recruiting
    - Bay Area Cardiology Assoc
    - Principal Investigator:
      
      Ranchhod Khant
    - Contact:
      
      Adrienne Gonzalez McTague
      
      Phone Number: +1 813 684 6000
      
      Email: adrienne@bayareacardiology.com
  - Jacksonville, Florida, United States, 32216
    - Recruiting
    - Jacksonville Center for Clinical Research
    - Principal Investigator:
      
      Michael J Koren
    - Contact:
      
      Theresa Hanburry
      
      Phone Number: +1 904 730 0101
      
      Email: thanburry@encoredocs.com
  - Naples, Florida, United States, 34102
    - Recruiting
    - Advanced Research for Health Improvement LLC
    - Principal Investigator:
      
      Julian Javier
    - Contact:
      
      Maria Caceres
      
      Phone Number: +1 239 300 0586
      
      Email: maria.caceres@arhiusa.com
  - Port Charlotte, Florida, United States, 33952
    - Recruiting
    - Peace River Cardiovascular Center
    - Contact:
      
      Karen Mullinax
      
      Phone Number: +1 941 629 5356
      
      Email: karen@prcvcfl.com
    - Principal Investigator:
      
      David Allan Hotchkiss
  - Port Orange, Florida, United States, 32127
    - Recruiting
    - Progressive Medical Research
    - Contact:
      
      Loria Jackie Boucher
      
      Phone Number: +1 386 304 7070
      
      Email: Jackieb@progressivemedicalresearch.com
    - Principal Investigator:
      
      Alexander J White
  - Saint Augustine, Florida, United States, 32086
    - Recruiting
    - East Coast Inst for Research LLC
    - Principal Investigator:
      
      Ferris George
    - Contact:
      
      Rebecca Fink
      
      Phone Number: +1 904 824 1776#116
      
      Email: becca.fink@roviaclinical.com
  - Wellington, Florida, United States, 33449
    - Recruiting
    - Cardiology Partners Clinical Research Institute
    - Contact:
      
      Saaima Farooq
      
      Phone Number: +1 561 537 4778
      
      Email: saaima.farooq@cardiologypartnerspl.com
    - Principal Investigator:
      
      Neerav Suresh Shah
- Georgia
  - Atlanta, Georgia, United States, 30322
    - Recruiting
    - Emory University
    - Principal Investigator:
      
      Arshed Quyyumi
    - Contact:
      
      Tanveer Kauser
      
      Phone Number: +1 404 712 4718
      
      Email: tanveer.kauser@emory.edu
  - Thomasville, Georgia, United States, 31792
    - Recruiting
    - Cardiovascular Consultants of S GA
    - Contact:
      
      Lauren Montgomery
      
      Phone Number: +1 229 584 5575
      
      Email: lauren@ccsgheart.com
    - Principal Investigator:
      
      Christopher Daniels
- Illinois
  - Chicago, Illinois, United States, 60612
    - Recruiting
    - Rush University Medical Center
    - Contact:
      
      Carmen M Petrizzo
      
      Phone Number: +1 312 563 2265
      
      Email: Carmen_M_Petrizzo@rush.edu
    - Principal Investigator:
      
      Annabelle Volgman
- Indiana
  - Indianapolis, Indiana, United States, 46202 4800
    - Recruiting
    - Krannert Institute of Cardiology
    - Principal Investigator:
      
      Julie Clary
    - Contact:
      
      Collin Lamothe
      
      Phone Number: +1 317 962 0500
      
      Email: clamothe@iu.edu
- Iowa
  - Iowa City, Iowa, United States, 52242
    - Recruiting
    - Uni Of Iowa Hospitals And Clinics
    - Principal Investigator:
      
      Marcelo Correia
    - Contact:
      
      Devona Chun-Furlong
      
      Phone Number: +1 319 384 5033
      
      Email: devona-chun-furlong@uiowa.edu
- Kansas
  - Kansas City, Kansas, United States, 66160
    - Recruiting
    - University of Kansas Hospital
    - Contact:
      
      Anne Nugent
      
      Phone Number: +1 913 945 5059
      
      Email: anugent@kumc.edu
    - Principal Investigator:
      
      Patrick M Moriarty
  - Topeka, Kansas, United States, 66606
    - Recruiting
    - Cotton O Neil Clinical Res Center
    - Principal Investigator:
      
      Michael Cox
    - Contact:
      
      D Amber Mauer
      
      Phone Number: +1 785 368 0745
      
      Email: DAmber.Mauer@stormontvail.org
- Louisiana
  - Covington, Louisiana, United States, 70433
    - Recruiting
    - Cardiovascular Associates Research
    - Principal Investigator:
      
      Dale Presser
    - Contact:
      
      Vicki L Nicely
      
      Phone Number: +1 985 892 2550
      
      Email: thestudygroup@bellsouth.net
  - Covington, Louisiana, United States, 70433
    - Recruiting
    - Louisiana Heart Center Research
    - Principal Investigator:
      
      Bruce J Iteld
    - Contact:
      
      Sherri Dragon
      
      Phone Number: +19853401966#113
      
      Email: s.dragon@laheart.org
  - Lafayette, Louisiana, United States, 70501
    - Recruiting
    - Horizon Research Grp
    - Contact:
      
      Stephanie Courville
      
      Phone Number: +1 337 457 8841
      
      Email: stephanie@horizonresearchgroup.com
    - Principal Investigator:
      
      Randall Miller
  - Metairie, Louisiana, United States, 70006
    - Recruiting
    - Omega Clinical Research
    - Principal Investigator:
      
      Tuan-Huy Tran
    - Contact:
      
      Tina Messina
      
      Phone Number: +1 504 914 8726
      
      Email: tmessinarn@gmail.com
  - New Orleans, Louisiana, United States, 70112
    - Recruiting
    - Tulane Center for Clinical Research
    - Contact:
      
      Suzanne Bowers
      
      Phone Number: +1 504 988 9190
      
      Email: Sbowers@tulane.edu
    - Principal Investigator:
      
      Keith C Ferdinand.
  - Opelousas, Louisiana, United States, 70570
    - Recruiting
    - CV Ins of the South
    - Principal Investigator:
      
      Siby George Ayalloore
    - Contact:
      
      Kammie Richard-Semien
      
      Phone Number: +1 337 942 3006
      
      Email: kammie.semien@cardio.com
  - Shreveport, Louisiana, United States, 71105
    - Recruiting
    - Grace Research Llc
    - Principal Investigator:
      
      Anil Chhabra
    - Contact:
      
      Kristen Terry
      
      Phone Number: +1 318 626 5180
      
      Email: Kristen.terry@graceresearchllc.com
  - Zachary, Louisiana, United States, 70791
    - Recruiting
    - Southern Clinical Research
    - Principal Investigator:
      
      Ernest Thompson
    - Contact:
      
      Michelle Gwyn
      
      Phone Number: +1 225 654 9901
      
      Email: michelle@southernclinicalresearch.com
- Maryland
  - Baltimore, Maryland, United States, 21209
    - Recruiting
    - Sinai Ct for Throm Res and Drug Dev
    - Principal Investigator:
      
      Paul Gurbel
    - Contact:
      
      Cescelle Barbour
      
      Phone Number: +1 410 367 2590
      
      Email: Cbarbour@lifebridgehealth.org
  - Columbia, Maryland, United States, 21044
    - Recruiting
    - Johns Hopkins University
    - Principal Investigator:
      
      Daniel Kim
    - Contact:
      
      Tanya Burley
      
      Email: tburley1@jhmi.edu
  - Ft. Washington, Maryland, United States, 20744
    - Recruiting
    - Anderson Medical Research
    - Principal Investigator:
      
      Felton Anderson
    - Contact:
      
      Ann-Marie Cobb
      
      Email: andersonmedicalresearch@gmail.com
  - Rockville, Maryland, United States, 20850
    - Recruiting
    - Adventist HealthCare Shady Grove Medical Center
    - Contact:
      
      Shilpa Rele
      
      Phone Number: +1 301 670 3000
      
      Email: srele@adventisthealthcare.com
    - Principal Investigator:
      
      Michael Chen
- Massachusetts
  - Boston, Massachusetts, United States, 02114 2696
    - Recruiting
    - MGH
    - Contact:
      
      Katherine Ward
      
      Email: kward18@mgh.harvard.edu
    - Principal Investigator:
      
      Maria T Vivaldi
- Michigan
  - Detroit, Michigan, United States, 48202
    - Recruiting
    - Henry Ford Hospital
    - Principal Investigator:
      
      Khaled Abdul-Nour
    - Contact:
      
      Meghan McCarthy
      
      Phone Number: +1 313 590 2407
      
      Email: mmccart8@hfhs.org
  - Detroit, Michigan, United States, 48201
    - Recruiting
    - Wayne State University
    - Principal Investigator:
      
      Brian J O Neil
    - Contact:
      
      Thomas Mazzocco
      
      Phone Number: +1 313 745 3246
      
      Email: tmazzocco@wayne.edu
  - Flint, Michigan, United States, 48504
    - Recruiting
    - AA Medical Research Center
    - Principal Investigator:
      
      Ahmed A Arif
    - Contact:
      
      Rania Takriti
      
      Phone Number: +1 810 237 1125
      
      Email: rtakriti@aamrc.net
  - Kalamazoo, Michigan, United States, 49008
    - Recruiting
    - Western Michigan University
    - Principal Investigator:
      
      Vishal Gupta
    - Contact:
      
      Debbi Hotchkiss
      
      Email: deborah.hotchkiss@wmed.edu
  - Petoskey, Michigan, United States, 49770
    - Recruiting
    - McLaren Ctr Research Innovation
    - Contact:
      
      Denise Antonishen
      
      Phone Number: +1 231 487 3116
      
      Email: denise.antonishen@mclaren.org
    - Principal Investigator:
      
      Joel Engel
  - Wyoming, Michigan, United States, 49519
    - Recruiting
    - Metro Health Univ of MI Health
    - Contact:
      
      Jensen Jantz
      
      Phone Number: +1 616 252 5104
      
      Email: jensen.jantz@umhwest.org
    - Principal Investigator:
      
      Rony Gorges
- Minnesota
  - Maplewood, Minnesota, United States, 55109
    - Recruiting
    - Saint Johns Hospital
    - Contact:
      
      Alexandra Clute
      
      Phone Number: +1 651 326 2328
      
      Email: Alexandra.clute@Fairview.org
    - Principal Investigator:
      
      Les B Forgosh
  - Minneapolis, Minnesota, United States, 55407
    - Recruiting
    - Minneapolis Heart Institute
    - Contact:
      
      Taylor Horn
      
      Phone Number: +1 612 863 6286
      
      Email: taylor.horn@allina.com
    - Principal Investigator:
      
      Thomas Knickelbine
  - Minneapolis, Minnesota, United States, 55455
    - Recruiting
    - University of Minnesota
    - Principal Investigator:
      
      Daniel Duprez
    - Contact:
      
      Michelle Pitt
      
      Phone Number: +1 612 624 4948
      
      Email: henni032@umn.edu
- Mississippi
  - Southaven, Mississippi, United States, 38671
    - Recruiting
    - Stern Cardiovascular Foundation Inc
    - Principal Investigator:
      
      Dharmesh Patel
    - Contact:
      
      Meshun Briscoe
      
      Phone Number: +1 901 271 2229
      
      Email: meshun.briscoe@sterncardio.com
- Missouri
  - City of Saint Peters, Missouri, United States, 63303
    - Recruiting
    - StudyMetrix Research
    - Principal Investigator:
      
      Timothy Smith
    - Contact:
      
      Elizabeth Maryas
      
      Phone Number: +1 6363875100
      
      Email: emaryas@studymetrix.com
- Nebraska
  - Omaha, Nebraska, United States, 68114
    - Recruiting
    - Quality Clinical Research
    - Contact:
      
      Melissa Frampton
      
      Phone Number: +1 402 934 0044
      
      Email: melissa.frampton@qcromaha.com
    - Principal Investigator:
      
      John Hallgren
- New Jersey
  - Summit, New Jersey, United States, 07901
    - Recruiting
    - Overlook Medical Center
    - Principal Investigator:
      
      Robert Fishberg
    - Contact:
      
      Rosmery Montesino
      
      Email: Rosmery.montesino@atlantichealth.org
- New York
  - Manhasset, New York, United States, 11030
    - Recruiting
    - Northwell Health
    - Principal Investigator:
      
      Bani Azari
    - Contact:
      
      Elizabeth Shin
      
      Phone Number: +1 516 562 4220
      
      Email: eshin7@northwell.edu
  - New York, New York, United States, 10021
    - Recruiting
    - Weill Cornell Medical Center
    - Principal Investigator:
      
      Samuel Kim
    - Contact:
      
      Rebecca Destin
      
      Phone Number: +1 212 746 2149
      
      Email: red4002@med.cornell.edu
  - New York, New York, United States, 43210
    - Recruiting
    - Lenox Hill Hospital
    - Principal Investigator:
      
      Eugenia Gianos
    - Contact:
      
      Lauren Senia
      
      Email: lsenia@northwell.edu
  - Riverhead, New York, United States, 11901
    - Recruiting
    - Northwell Health Physician Peconic
    - Principal Investigator:
      
      Sean Donahoe
    - Contact:
      
      Laura Jens-Smith
      
      Phone Number: +1 631 702 8936
      
      Email: ljenssmith@northwell.edu
- North Carolina
  - Charlotte, North Carolina, United States, 28204
    - Recruiting
    - Novant Health Heart Vas Inst
    - Principal Investigator:
      
      Anish Vani
    - Contact:
      
      Alanza Ferguson
      
      Phone Number: +1 704 264 1400
      
      Email: aaferguson@novanthealth.org
  - Greensboro, North Carolina, United States, 27405
    - Recruiting
    - Medication Management LLC
    - Principal Investigator:
      
      James Franklin
    - Contact:
      
      Stephanie Phillips
      
      Phone Number: +1 336 412 1002
      
      Email: stephanie.phillips@emailmm.com
  - Raleigh, North Carolina, United States, 27609
    - Recruiting
    - Accellacare US Inc
    - Principal Investigator:
      
      John Rubino
    - Contact:
      
      Jeana Kelliher
      
      Phone Number: +1 919 782 4895
      
      Email: jeana.kelliher@accellacare.com
  - Winston-Salem, North Carolina, United States, 27157
    - Recruiting
    - Wake Forest University Baptist Medical Center
    - Principal Investigator:
      
      Michael Shapiro
    - Contact:
      
      Keishia Rodriguez
      
      Phone Number: +1 336 716 3775
      
      Email: keishia.rodriguez@advocatehealth.org
- Ohio
  - Canton, Ohio, United States, 44710
    - Recruiting
    - Aultman Hospital
    - Contact:
      
      Barbara Rambaud
      
      Phone Number: +1 330 489 9053
      
      Email: barbara.rambaud@aultman.com
    - Principal Investigator:
      
      Ramana Podugu
  - Cincinnati, Ohio, United States, 45219
    - Recruiting
    - Lindner Ctr At The Christ Hosp
    - Contact:
      
      Meghan Grone
      
      Phone Number: +1 513 585 1777
      
      Email: Meghan.Grone@thechristhospital.com
    - Principal Investigator:
      
      Dean J Kereiakes
  - Marion, Ohio, United States, 43302
    - Recruiting
    - Rama Research LLC
    - Principal Investigator:
      
      Bhola Rama
    - Contact:
      
      Rhonda Rudd
      
      Phone Number: +1 740 383 7039
      
      Email: Rruddcrc@gmail.com
- Pennsylvania
  - Lancaster, Pennsylvania, United States, 17603
    - Recruiting
    - Lancaster General Health
    - Contact:
      
      Kay Knepper
      
      Email: Kay.Knepper@pennmedicine.upenn.edu
    - Principal Investigator:
      
      Marjan U Mujib
  - Yardley, Pennsylvania, United States, 19067
    - Recruiting
    - Cardiology Consultants of Philadelphia
    - Principal Investigator:
      
      Paul Grena
    - Contact:
      
      Sharon Budzinski
      
      Phone Number: +1 215 321 7400#242
      
      Email: sharonb@ccpdocs.com
- South Dakota
  - Rapid City, South Dakota, United States, 57701
    - Recruiting
    - Monument Health Clinical Research
    - Contact:
      
      Chelsie Taylor
      
      Phone Number: +1 605 755 4326
      
      Email: ctaylor2@monument.health
    - Principal Investigator:
      
      Stephen Wasemiller
- Tennessee
  - Germantown, Tennessee, United States, 38138
    - Recruiting
    - The Stern Cardiovascular Foundation
    - Principal Investigator:
      
      Frank Augustus McGrew
    - Contact:
      
      Rishi Bhula
      
      Phone Number: +1 901 271 4063
      
      Email: rishi.bhula@sterncardio.com
  - Jackson, Tennessee, United States, 38301
    - Recruiting
    - Apex Cardiology Research Associates of Jackson
    - Principal Investigator:
      
      Mohsin Alhaddad
    - Contact:
      
      Pam Gibbons
      
      Phone Number: +1 731 423 8200
      
      Email: pgibbons@researchjackson.com
  - Nashville, Tennessee, United States, 37232
    - Recruiting
    - Vanderbilt Univ Medi Cen
    - Contact:
      
      Anca M Ifrim
      
      Phone Number: +1 615 936 1641
      
      Email: anca.m.ifrim@vumc.org
    - Principal Investigator:
      
      MacRae Linton
  - Powell, Tennessee, United States, 37849
    - Recruiting
    - Cardiovascular Res of Knoxville LLC
    - Principal Investigator:
      
      Charles B Treasure
    - Contact:
      
      Thea Baker
      
      Phone Number: +1 865 523 9006
      
      Email: tbaker@crknox.net
- Texas
  - Dallas, Texas, United States, 75231
    - Recruiting
    - North Texas Endocrine Center
    - Principal Investigator:
      
      Peter Bressler
    - Contact:
      
      Anusha Haidry
      
      Phone Number: +1 214 369 5992
      
      Email: ahaidry@ntendocenter.com
  - Dallas, Texas, United States, 75226
    - Recruiting
    - Soltero Cardiovascular Research Center
    - Principal Investigator:
      
      Cara East
    - Contact:
      
      Merielle Boatman
      
      Phone Number: +1 214 820 2273
      
      Email: Merielle.Boatman@BSWHealth.org
  - Dallas, Texas, United States, 75235
    - Recruiting
    - SW Family Medicine Associates
    - Principal Investigator:
      
      Chrisette Dharma
    - Contact:
      
      Safia Shaikh
      
      Phone Number: +1 214 393 2940
      
      Email: sshaikh@swmedicalgroup.com
  - Houston, Texas, United States, 77030
    - Recruiting
    - Baylor College of Medicine
    - Contact:
      
      Sharon Goss
      
      Phone Number: +1 713 798 5845
      
      Email: sgoss@bcm.edu
    - Principal Investigator:
      
      Christie M Ballantyne
  - Marshall, Texas, United States, 75670
    - Recruiting
    - Grace Research
    - Principal Investigator:
      
      William Eaves
    - Contact:
      
      Melissa Moore
      
      Phone Number: +1 318 626 5180
      
      Email: melissa.moore@graceresearchllc.com
  - Tomball, Texas, United States, 77375
    - Recruiting
    - Northwest Houston Clinical Research PLLC
    - Principal Investigator:
      
      Shamaila Aslam
    - Contact:
      
      Dawn Burns
      
      Phone Number: +1 281 351 4911
      
      Email: dburns@houstonheartcenter.com
- Utah
  - Bountiful, Utah, United States, 84010
    - Recruiting
    - Progressive Clinical Research
    - Principal Investigator:
      
      Joshua Oaks
    - Contact:
      
      Gregory W Toole
      
      Phone Number: +1801 292 1422
      
      Email: greg@progressiveclinicalresearch.com
  - Murray, Utah, United States, 84107
    - Recruiting
    - Intermountain Medical Center
    - Principal Investigator:
      
      Jeffrey Anderson
    - Contact:
      
      Erin Call
      
      Phone Number: +1 801 507 4707
      
      Email: Erin.Call@imail.org
  - Salt Lake City, Utah, United States, 84132-0001
    - Recruiting
    - The University of Utah
    - Contact:
      
      Theodore Rock
      
      Phone Number: +1 801 587 7919
      
      Email: Theodore.rock@hsc.utah.edu
    - Principal Investigator:
      
      Aaron Shoskes
- Virginia
  - Falls Church, Virginia, United States, 22042
    - Recruiting
    - Inova Fairfax Hospital
    - Contact:
      
      Joanne Wotring
      
      Email: Joanne.Wotring@inova.org
    - Principal Investigator:
      
      Jared Spitz
  - Falls Church, Virginia, United States, 22042
    - Recruiting
    - Virginia Heart
    - Principal Investigator:
      
      Tariq Haddad
    - Contact:
      
      Oyinda Agbale
      
      Phone Number: +1 703 766 5920
      
      Email: oagbale@virginiaheart.com
  - Manassas, Virginia, United States, 20109
    - Recruiting
    - Carient Heart and Vascular
    - Principal Investigator:
      
      Vikram Prasanna
    - Contact:
      
      Rafael Muro
      
      Phone Number: +1 70 333 58 750
      
      Email: rmuro@carient.com
  - Richmond, Virginia, United States, 23219
    - Recruiting
    - Dominion Medical Associates
    - Principal Investigator:
      
      Richard A Jackson
    - Contact:
      
      Richard AJ Jackson
      
      Phone Number: +1 804 249 2111
      
      Email: aj@dominionmedicalinc.com
- Washington
  - Seattle, Washington, United States, 98104
    - Recruiting
    - Harborview Medical Center
    - Principal Investigator:
      
      Francis Kim
    - Contact:
      
      Daniel Isquith
      
      Phone Number: +1 206 744 8305
      
      Email: disquith@uw.edu
  - Seattle, Washington, United States, 98122
    - Recruiting
    - Swedish Medical Center-Cardiovascular Research
    - Contact:
      
      Serena Risher
      
      Phone Number: +1 206 215 2466
      
      Email: Serena.Risher@swedish.org
    - Principal Investigator:
      
      John Petersen II.
- West Virginia
  - Morgantown, West Virginia, United States, 26506
    - Recruiting
    - West Virginia University Hospital
    - Principal Investigator:
      
      Sudarshan Balla
    - Contact:
      
      Tanja Aucremanne
      
      Phone Number: 13042930609
      
      Email: tanja.aucremanne1@wvumedicine.org

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

Adult
Older Adult

Accepts Healthy Volunteers

Description

Inclusion Criteria:

Participants who have provided informed consent prior to initiation of any study-specific activities/procedures.
Participants who have completed the parent study EOS visit while still on assigned investigational product.

Exclusion Criteria:

Participants who for any reason permanently discontinued or have interrupted the investigational product for continuous 6 months at EOS during the parent study.
Participants who have a history or evidence of any clinically significant disorder, condition, or disease that in the opinion of the investigator or Novartis physician (if consulted), would put the participant at risk or interfere with the study participation, including, but not restricted to conditions outlined in Table 6-3 and Table 6-5.
Participants are receiving another investigational drug or device before the open-label treatment period.
Participants have a known sensitivity to the study drug and are deemed as unsuited for the study by the Investigator at Screening visit.

Other protocol-defined inclusion/exclusion criteria may apply.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Primary Purpose: Treatment
Allocation: N/A
Interventional Model: Single Group Assignment
Masking: None (Open Label)

Number of Arms

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Pelacarsen (TQJ230) open-label pelacarsen 80mg	Drug: Pelacarsen (TQJ230) pelacarsen 80mg s.c. monthly Other Names: TQJ230

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of participants with Adverse events Time Frame: Up to 36 months	Number of participants with Treatment Emergent Adverse Events (TEAEs), Treatment Emergent Serious Adverse Events (TESAEs), TEAEs of special interest, including abnormal laboratory evaluations and vital signs. Number of participants discontinuing due to treatment emergent adverse events (TEAEs) or treatment emergent serious adverse events (TESAEs) will also be presented.	Up to 36 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to first occurrence of 4 Point-Major Cardiovascular Event (4P-MACE) from parent study baseline Time Frame: Up to 36 months	Time to first occurrence of 4P-MACE (cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, or urgent coronary revascularization requiring hospitalization) from the beginning of the parent study will be presented	Up to 36 months
Time to the first occurrence of 4P-MACE from open-label extension (OLE) study baseline Time Frame: Up to 36 months	Time to first occurrence of 4P-MACE (cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, or urgent coronary revascularization requiring hospitalization) from the beginning of the OLE study will be presented	Up to 36 months
Cumulative number of 4P-MACE over time from OLE study baseline Time Frame: Up to 36 months	Cumulative number of 4P-MACE (cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, or urgent coronary revascularization requiring hospitalization) over time from the beginning of the OLE study will be presented	Up to 36 months
Cumulative number of 4P-MACE over time from parent study baseline Time Frame: Up to 36 months	Cumulative number of 4P-MACE (cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, or urgent coronary revascularization requiring hospitalization) over time from the beginning of the parent study will be presented	Up to 36 months
Observed value of Lipoprotein(a) (Lp(a)) Time Frame: Baseline, Month 3, Month 12, Month 24, Month 36	Samples for Lp(a) assessment will be collected at the defined time points, analyzed and values reported.	Baseline, Month 3, Month 12, Month 24, Month 36
Change in Lp(a) compared to baseline of the OLE study Time Frame: Baseline, Month 3, Month 12, Month 24, Month 36	Samples for Lp(a) assessment will be collected at defined time points and change will be calculated against baseline of the OLE study.	Baseline, Month 3, Month 12, Month 24, Month 36
Change in Lp(a) compared to baseline of the parent study Time Frame: Baseline, Month 3, Month 12, Month 24, Month 36	Samples for Lp(a) assessment will be collected at defined time points and change will be calculated against baseline of the parent study.	Baseline, Month 3, Month 12, Month 24, Month 36

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Novartis Pharmaceuticals

Investigators

Study Director: Novartis Pharmaceuticals, Novartis Pharmaceuticals

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 11, 2026

Primary Completion (Estimated)

January 9, 2030

Study Completion (Estimated)

January 9, 2030

Study Registration Dates

First Submitted

April 1, 2026

First Submitted That Met QC Criteria

April 1, 2026

First Posted (Actual)

April 8, 2026

Study Record Updates

Last Update Posted (Actual)

May 18, 2026

Last Update Submitted That Met QC Criteria

May 14, 2026

Last Verified

May 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

CTQJ230A12301E1
2024-519870-38-00 (Other Identifier: EU CT)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

Novartis is committed to sharing with qualified external researchers, access to patient-level data and supporting clinical documents from eligible studies. These requests are reviewed and approved by an independent review panel on the basis of scientific merit. All data provided is anonymized to respect the privacy of patients who have participated in the trial in line with applicable laws and regulations. This trial data availability is according to the criteria and process described on www.clinicalstudydatarequest.com.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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Study Overview

Status

Conditions

Intervention / Treatment

Detailed Description

Study Type

Enrollment (Estimated)

Phase

Contacts and Locations

Study Contact

Study Contact Backup

Study Locations

Participation Criteria

Eligibility Criteria

Ages Eligible for Study

Accepts Healthy Volunteers

Description

Study Plan

How is the study designed?

Design Details

Number of Arms

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Secondary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Collaborators and Investigators

Sponsor

Investigators

Study record dates

Study Major Dates

Study Start (Actual)

Primary Completion (Estimated)

Study Completion (Estimated)

Study Registration Dates

First Submitted

First Submitted That Met QC Criteria

First Posted (Actual)

Study Record Updates

Last Update Posted (Actual)

Last Update Submitted That Met QC Criteria

Last Verified

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

IPD Plan Description

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Studies a U.S. FDA-regulated device product

Clinical Trials on Cardiovascular Disease and Lipoprotein(a)

Clinical Trials on Pelacarsen (TQJ230)

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