A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF (Elevate-HF)

September 4, 2026 updated by: AstraZeneca

A Phase III, Randomized, Double-blind, Parallel-group, Placebo-controlled, Multicenter Study to Evaluate the Effect of Elecoglipron in Reducing Cardiovascular Outcomes in Participants With HFpEF and HFmrEF (Elevate-HF)

This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled, multicenter study to investigate CV outcomes with elecoglipron compared with placebo, in adults with heart failure with preserved ejection fraction (HFpEF)/heart failure with mildly reduced ejection fraction (HFmrEF), irrespective of T2DM status, and who are on background dapagliflozin in addition to other background standard of care.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

6950

Phase

Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Name: AstraZeneca Clinical Study Information Center
Phone Number: 1-877-240-9479
Email: information.center@astrazeneca.com

Study Locations

Argentina
- - Buenos Aires, Argentina, C1425AGC
    - Not yet recruiting
    - Research Site
  - CABA, Argentina, C1061
    - Not yet recruiting
    - Research Site
  - Ciudad de Buenos Aires, Argentina, 1060
    - Not yet recruiting
    - Research Site
  - Ciudad de Buenos Aires, Argentina, C1428
    - Not yet recruiting
    - Research Site
  - Corrientes, Argentina, 3400
    - Not yet recruiting
    - Research Site
  - Córdoba, Argentina, X5003DCE
    - Not yet recruiting
    - Research Site
  - Córdoba, Argentina, 5000
    - Not yet recruiting
    - Research Site
  - Córdoba, Argentina, X5006CBI
    - Not yet recruiting
    - Research Site
  - Esperanza, Argentina, S3080BQU
    - Not yet recruiting
    - Research Site
  - Granadero Baigorria, Argentina, S2152BOF
    - Not yet recruiting
    - Research Site
  - Lanus, Argentina, B1824KAJ
    - Not yet recruiting
    - Research Site
  - Mar del Plata, Argentina, B7600GNY
    - Not yet recruiting
    - Research Site
  - Mendoza, Argentina, 5500
    - Not yet recruiting
    - Research Site
  - Rosario, Argentina, S2000PBJ
    - Not yet recruiting
    - Research Site
  - Rosario, Argentina, S2000CVD
    - Not yet recruiting
    - Research Site
  - San Nicolás, Argentina, B2900ACL
    - Not yet recruiting
    - Research Site
  - Santa Fe, Argentina, S3000FWO
    - Not yet recruiting
    - Research Site
Australia
- - Blacktown, Australia, 2148
    - Not yet recruiting
    - Research Site
  - Campbelltown, Australia, 2560
    - Not yet recruiting
    - Research Site
  - Frankston, Australia, 3199
    - Not yet recruiting
    - Research Site
  - Hoppers Crossing, Australia, 3029
    - Not yet recruiting
    - Research Site
  - North Tamworth, Australia, 2340
    - Not yet recruiting
    - Research Site
  - Rockhampton, Australia, 4700
    - Not yet recruiting
    - Research Site
Austria
- - Bad Ischl, Austria, 4820
    - Not yet recruiting
    - Research Site
  - Feldkirch, Austria, 6800
    - Not yet recruiting
    - Research Site
  - Graz, Austria, 8036
    - Not yet recruiting
    - Research Site
  - Graz, Austria, 8020
    - Not yet recruiting
    - Research Site
  - Innsbruck, Austria, 6020
    - Not yet recruiting
    - Research Site
  - Klagenfurt, Austria, 9020
    - Not yet recruiting
    - Research Site
  - Linz, Austria, 4021
    - Not yet recruiting
    - Research Site
  - Saint Stefan/Stainz, Austria, 8511
    - Not yet recruiting
    - Research Site
  - Sankt Pölten, Austria, 3100
    - Not yet recruiting
    - Research Site
  - Vienna, Austria, 1090
    - Not yet recruiting
    - Research Site
  - Vienna, Austria, 1210
    - Not yet recruiting
    - Research Site
  - Vienna, Austria, 1100
    - Not yet recruiting
    - Research Site
  - Vienna, Austria, 1160
    - Not yet recruiting
    - Research Site
  - Wels, Austria, 4600
    - Not yet recruiting
    - Research Site
Brazil
- - Aracaju, Brazil, 49015-380
    - Not yet recruiting
    - Research Site
  - Belém, Brazil, 66073-005
    - Not yet recruiting
    - Research Site
  - Bragança Paulista, Brazil, 12916-542
    - Not yet recruiting
    - Research Site
  - Brasília, Brazil, 70390-700
    - Not yet recruiting
    - Research Site
  - Campinas, Brazil, 13060-080
    - Not yet recruiting
    - Research Site
  - Curitiba, Brazil, 80230-130
    - Not yet recruiting
    - Research Site
  - Joinville, Brazil, 89204-251
    - Not yet recruiting
    - Research Site
  - Natal, Brazil, 59020-035
    - Not yet recruiting
    - Research Site
  - Porto Alegre, Brazil, 91350-280
    - Not yet recruiting
    - Research Site
  - Porto Alegre, Brazil, 90630-165
    - Not yet recruiting
    - Research Site
  - Ribeirão Preto, Brazil, 14051-140
    - Not yet recruiting
    - Research Site
  - Rio Branco, Brazil, 69915-030
    - Not yet recruiting
    - Research Site
  - Rio de Janeiro, Brazil, 22270-060
    - Not yet recruiting
    - Research Site
  - São Paulo, Brazil, 04012-180
    - Withdrawn
    - Research Site
Bulgaria
- - Blagoevgrad, Bulgaria, 2700
    - Not yet recruiting
    - Research Site
  - Dupnitsa, Bulgaria, 2600
    - Not yet recruiting
    - Research Site
  - Haskovo, Bulgaria, 6300
    - Not yet recruiting
    - Research Site
  - Haskovo, Bulgaria, 6304
    - Not yet recruiting
    - Research Site
  - Plovdiv, Bulgaria, 4023
    - Not yet recruiting
    - Research Site
  - Plovdiv, Bulgaria, 4000
    - Not yet recruiting
    - Research Site
  - Sliven, Bulgaria, 8800
    - Not yet recruiting
    - Research Site
  - Sofia, Bulgaria, 1618
    - Not yet recruiting
    - Research Site
  - Sofia, Bulgaria, 1000
    - Not yet recruiting
    - Research Site
  - Sofia, Bulgaria, 1680
    - Not yet recruiting
    - Research Site
  - Sofia, Bulgaria, 1527
    - Not yet recruiting
    - Research Site
  - Sofia, Bulgaria, 1756
    - Not yet recruiting
    - Research Site
  - Sofia, Bulgaria, 1404
    - Not yet recruiting
    - Research Site
  - Sofia, Bulgaria, 1309
    - Not yet recruiting
    - Research Site
  - Varna, Bulgaria, 9000
    - Not yet recruiting
    - Research Site
Canada
- Ontario
  - Barrie, Ontario, Canada, L4M 6M2
    - Not yet recruiting
    - Research Site
  - Etobicoke, Ontario, Canada, M8Z 4E4
    - Not yet recruiting
    - Research Site
  - Greater Sudbury, Ontario, Canada, P3E 5J1
    - Not yet recruiting
    - Research Site
  - Hamilton, Ontario, Canada, L8L 5G4
    - Not yet recruiting
    - Research Site
  - Kingston, Ontario, Canada, K7M 7E4
    - Not yet recruiting
    - Research Site
  - London, Ontario, Canada, N6A 5W9
    - Withdrawn
    - Research Site
  - London, Ontario, Canada, N6A 5A5
    - Not yet recruiting
    - Research Site
  - Markham, Ontario, Canada, L3S 0A2
    - Not yet recruiting
    - Research Site
  - Markham, Ontario, Canada, L3P 7P3
    - Not yet recruiting
    - Research Site
  - Newmarket, Ontario, Canada, L3Y 2P6
    - Recruiting
    - Research Site
  - North York, Ontario, Canada, M6B 3H7
    - Recruiting
    - Research Site
  - North York, Ontario, Canada, M9N 1W4
    - Withdrawn
    - Research Site
  - Oakville, Ontario, Canada, L6K 3W7
    - Not yet recruiting
    - Research Site
  - Ottawa, Ontario, Canada, K1Y 4W7
    - Not yet recruiting
    - Research Site
  - Stoney Creek, Ontario, Canada, L8J 3W2
    - Recruiting
    - Research Site
  - Thunder Bay, Ontario, Canada, P7B 5N3
    - Not yet recruiting
    - Research Site
  - Thunder Bay, Ontario, Canada, P7B 5N3
    - Withdrawn
    - Research Site
  - Toronto, Ontario, Canada, M4N 3M5
    - Not yet recruiting
    - Research Site
  - Toronto, Ontario, Canada, M6G 1M2
    - Not yet recruiting
    - Research Site
- Quebec
  - Montreal, Quebec, Canada, H4A 3J1
    - Not yet recruiting
    - Research Site
  - Trois-Rivières, Quebec, Canada, G8Z 3R9
    - Not yet recruiting
    - Research Site
China
- - Baoding, China, 072750
    - Not yet recruiting
    - Research Site
  - Beijing, China, 100142
    - Not yet recruiting
    - Research Site
  - Beijing, China, 100050
    - Not yet recruiting
    - Research Site
  - Beijing, China, 100044
    - Not yet recruiting
    - Research Site
  - Beijing, China, 100034
    - Not yet recruiting
    - Research Site
  - Beijing, China, 100053
    - Not yet recruiting
    - Research Site
  - Beijing, China
    - Not yet recruiting
    - Research Site
  - Beijing, China, 100037
    - Not yet recruiting
    - Research Site
  - Beijing, China, 100000
    - Not yet recruiting
    - Research Site
  - Beijing, China, 100022
    - Not yet recruiting
    - Research Site
  - Bozhou, China, 236000
    - Not yet recruiting
    - Research Site
  - Changchun, China, 130021
    - Not yet recruiting
    - Research Site
  - Changchun, China, 130041
    - Not yet recruiting
    - Research Site
  - Changde, China, 415000
    - Not yet recruiting
    - Research Site
  - Changsha, China, 410300
    - Withdrawn
    - Research Site
  - Chengdu, China, 610041
    - Not yet recruiting
    - Research Site
  - Chengdu, China, 610031
    - Not yet recruiting
    - Research Site
  - Chengdu, China, 610078
    - Not yet recruiting
    - Research Site
  - Chifeng, China, 024000
    - Not yet recruiting
    - Research Site
  - Daqing, China, 163000
    - Not yet recruiting
    - Research Site
  - Foshan, China, 528308
    - Not yet recruiting
    - Research Site
  - Guangzhou, China, 510000
    - Not yet recruiting
    - Research Site
  - Guangzhou, China, 510289
    - Not yet recruiting
    - Research Site
  - Haikou, China, 570311
    - Not yet recruiting
    - Research Site
  - Hefei, China, 230601
    - Not yet recruiting
    - Research Site
  - Heze, China, 274099
    - Not yet recruiting
    - Research Site
  - Huaian, China, 223300
    - Not yet recruiting
    - Research Site
  - Huizhou, China, 516002
    - Not yet recruiting
    - Research Site
  - Jiangmen, China, 529000
    - Not yet recruiting
    - Research Site
  - Jinan, China, 250012
    - Not yet recruiting
    - Research Site
  - Jinan, China, 250031
    - Not yet recruiting
    - Research Site
  - Jining, China, 272006
    - Not yet recruiting
    - Research Site
  - Lanzhou, China, 730000
    - Not yet recruiting
    - Research Site
  - Linhai, China, 317000
    - Not yet recruiting
    - Research Site
  - Lishui, China, 323000
    - Not yet recruiting
    - Research Site
  - Luoyang, China, 471001
    - Not yet recruiting
    - Research Site
  - Nanchang, China, 330009
    - Not yet recruiting
    - Research Site
  - Nanjing, China, 2100008
    - Not yet recruiting
    - Research Site
  - Nanjing, China, 210009
    - Not yet recruiting
    - Research Site
  - Nanjing, China, 210011
    - Not yet recruiting
    - Research Site
  - Nanyang, China, 473000
    - Not yet recruiting
    - Research Site
  - Ningbo, China, 315000
    - Not yet recruiting
    - Research Site
  - Panjin, China, 124009
    - Not yet recruiting
    - Research Site
  - Pingxiang, China, 337055
    - Not yet recruiting
    - Research Site
  - Qingzhou, China, 262550
    - Not yet recruiting
    - Research Site
  - Sanya, China, 572000
    - Not yet recruiting
    - Research Site
  - Shanghai, China, 201107
    - Not yet recruiting
    - Research Site
  - Shanghai, China, 201199
    - Not yet recruiting
    - Research Site
  - Shanghai, China, 200090
    - Not yet recruiting
    - Research Site
  - Shanghai, China, 200135
    - Not yet recruiting
    - Research Site
  - Shantou, China, 515041
    - Not yet recruiting
    - Research Site
  - Shaoguan, China, 512027
    - Not yet recruiting
    - Research Site
  - Shaoxing, China, 312000
    - Not yet recruiting
    - Research Site
  - Shenyang, China, 110016
    - Not yet recruiting
    - Research Site
  - Shenzhen, China, 518053
    - Not yet recruiting
    - Research Site
  - Siping, China, 136000
    - Not yet recruiting
    - Research Site
  - Suining, China, 629000
    - Not yet recruiting
    - Research Site
  - Suzhou, China, 215004
    - Not yet recruiting
    - Research Site
  - Suzhou, China, 215006
    - Not yet recruiting
    - Research Site
  - Taian, China, 271099
    - Not yet recruiting
    - Research Site
  - Tianjin, China, 300000
    - Not yet recruiting
    - Research Site
  - Tianjin, China, 300050
    - Withdrawn
    - Research Site
  - Wanzhou, China, 404000
    - Not yet recruiting
    - Research Site
  - Weifang, China, 261000
    - Not yet recruiting
    - Research Site
  - Wenzhou, China, 325000
    - Not yet recruiting
    - Research Site
  - Wuhan, China, 430000
    - Not yet recruiting
    - Research Site
  - Wuhan, China, 430033
    - Not yet recruiting
    - Research Site
  - Wuxi, China, 214023
    - Not yet recruiting
    - Research Site
  - Xi'an, China, 710061
    - Not yet recruiting
    - Research Site
  - Xi'an, China, 710068
    - Not yet recruiting
    - Research Site
  - Xiangtan, China, 411100
    - Not yet recruiting
    - Research Site
  - Xuzhou, China, 221000
    - Not yet recruiting
    - Research Site
  - Xuzhou, China, 221009
    - Not yet recruiting
    - Research Site
  - Yancheng, China, 224005
    - Not yet recruiting
    - Research Site
  - Yangzhou, China, 225001
    - Not yet recruiting
    - Research Site
  - Yueyang, China, 414000
    - Not yet recruiting
    - Research Site
  - Yuncheng, China, 044099
    - Not yet recruiting
    - Research Site
  - Zhangjiakou, China, 075061
    - Not yet recruiting
    - Research Site
  - Zhengzhou, China, 450052
    - Not yet recruiting
    - Research Site
  - Zhengzhou, China, 450007
    - Not yet recruiting
    - Research Site
  - Zhengzhou, China, 450002
    - Withdrawn
    - Research Site
  - Zibo, China, 255036
    - Not yet recruiting
    - Research Site
  - Zigong, China, 643021
    - Not yet recruiting
    - Research Site
  - Zunyi, China, 563100
    - Not yet recruiting
    - Research Site
  - Ürümqi, China, 830001
    - Not yet recruiting
    - Research Site
Czechia
- - Benešov, Czechia, 256 01
    - Not yet recruiting
    - Research Site
  - Boskovice, Czechia, 680 01
    - Not yet recruiting
    - Research Site
  - Brno, Czechia, 60200
    - Not yet recruiting
    - Research Site
  - Broumov, Czechia, 55001
    - Not yet recruiting
    - Research Site
  - Chlumec nad Cidlinou, Czechia, 503 51
    - Withdrawn
    - Research Site
  - Hradec Králové, Czechia, 500 02
    - Not yet recruiting
    - Research Site
  - Hustopeče, Czechia, 693 01
    - Not yet recruiting
    - Research Site
  - Jaroměř, Czechia, 551 01
    - Not yet recruiting
    - Research Site
  - Kadaň, Czechia, 432 01
    - Withdrawn
    - Research Site
  - Klatovy, Czechia, 339 01
    - Not yet recruiting
    - Research Site
  - Liberec, Czechia, 460 01
    - Not yet recruiting
    - Research Site
  - Louny, Czechia, 440 01
    - Not yet recruiting
    - Research Site
  - Prague, Czechia, 130 00
    - Not yet recruiting
    - Research Site
  - Prague, Czechia, 150 00
    - Not yet recruiting
    - Research Site
  - Prague, Czechia, 150 00
    - Withdrawn
    - Research Site
  - Prague, Czechia, 198 00
    - Not yet recruiting
    - Research Site
  - Teplice, Czechia, 415 01
    - Not yet recruiting
    - Research Site
  - Vsetín, Czechia, 755 01
    - Not yet recruiting
    - Research Site
  - Česká Lípa, Czechia, 470 77
    - Withdrawn
    - Research Site
  - Český Krumlov, Czechia, 381 01
    - Not yet recruiting
    - Research Site
France
- - Bron, France, 69667
    - Not yet recruiting
    - Research Site
  - Corbeil-Essonnes, France, 91100
    - Not yet recruiting
    - Research Site
  - La Tronche, France, 38043
    - Not yet recruiting
    - Research Site
  - Le Coudray, France, 28630
    - Not yet recruiting
    - Research Site
  - Lens, France, 62300
    - Not yet recruiting
    - Research Site
  - Metz-Tessy, France, 74370
    - Not yet recruiting
    - Research Site
  - Pau, France, 6400
    - Not yet recruiting
    - Research Site
  - Rennes, France, 35033
    - Not yet recruiting
    - Research Site
  - Rodez, France, 12000
    - Not yet recruiting
    - Research Site
  - Rouen, France, 76031
    - Not yet recruiting
    - Research Site
  - Saint-Brieuc, France, 22027
    - Not yet recruiting
    - Research Site
  - Toulon, France, 83100
    - Not yet recruiting
    - Research Site
  - Vandœuvre-lès-Nancy, France, 54511
    - Not yet recruiting
    - Research Site
Germany
- - Bad Oldesloe, Germany, 23843
    - Not yet recruiting
    - Research Site
  - Bamberg, Germany, 96049
    - Not yet recruiting
    - Research Site
  - Berlin, Germany, 13187
    - Withdrawn
    - Research Site
  - Berlin, Germany, 13509
    - Not yet recruiting
    - Research Site
  - Berlin, Germany, 13405
    - Not yet recruiting
    - Research Site
  - Bielefeld, Germany, 33604
    - Not yet recruiting
    - Research Site
  - Bochum, Germany, 44789
    - Not yet recruiting
    - Research Site
  - Bremen, Germany, 28277
    - Not yet recruiting
    - Research Site
  - Chemnitz, Germany, 09116
    - Not yet recruiting
    - Research Site
  - Cologne, Germany, 50733
    - Not yet recruiting
    - Research Site
  - Dresden, Germany, 1307
    - Not yet recruiting
    - Research Site
  - Elsterwerda, Germany, 04910
    - Not yet recruiting
    - Research Site
  - Erlangen, Germany, 91504
    - Not yet recruiting
    - Research Site
  - Essen, Germany, 45147
    - Not yet recruiting
    - Research Site
  - Freiburg im Breisgau, Germany, 79106
    - Not yet recruiting
    - Research Site
  - Gera, Germany, 07548
    - Not yet recruiting
    - Research Site
  - Hamburg, Germany, 20099
    - Not yet recruiting
    - Research Site
  - Hamburg, Germany, 22459
    - Not yet recruiting
    - Research Site
  - Hamburg, Germany, 21075
    - Not yet recruiting
    - Research Site
  - Hamburg, Germany, 22559
    - Not yet recruiting
    - Research Site
  - Heidelberg, Germany, 69120
    - Not yet recruiting
    - Research Site
  - Homburg, Germany, 66424
    - Not yet recruiting
    - Research Site
  - Jena, Germany, 07747
    - Not yet recruiting
    - Research Site
  - Kaiserslautern, Germany, 67655
    - Not yet recruiting
    - Research Site
  - Karlsbad, Germany, 76307
    - Not yet recruiting
    - Research Site
  - Kiel, Germany, 24105
    - Not yet recruiting
    - Research Site
  - Ludwigshafen, Germany, 67063
    - Not yet recruiting
    - Research Site
  - Ludwigshafen am Rhein, Germany, 67071
    - Not yet recruiting
    - Research Site
  - Lüneburg, Germany, 21339
    - Not yet recruiting
    - Research Site
  - Magdeburg, Germany, 39120
    - Not yet recruiting
    - Research Site
  - Mainz, Germany, 55131
    - Not yet recruiting
    - Research Site
  - Mainz, Germany, 55122
    - Recruiting
    - Research Site
  - Markkleeberg, Germany, 04416
    - Suspended
    - Research Site
  - Mühldorf A. Inn, Germany, 84453
    - Not yet recruiting
    - Research Site
  - Neuruppin, Germany, 16816
    - Not yet recruiting
    - Research Site
  - Nuremberg, Germany, 90402
    - Not yet recruiting
    - Research Site
  - Obertshausen, Germany, 63179
    - Not yet recruiting
    - Research Site
  - Paderborn, Germany, 33098
    - Not yet recruiting
    - Research Site
  - Papenburg, Germany, 26871
    - Suspended
    - Research Site
  - Stuttgart, Germany, 70199
    - Not yet recruiting
    - Research Site
  - Trier, Germany, 54292
    - Not yet recruiting
    - Research Site
  - Tübingen, Germany, 72076
    - Not yet recruiting
    - Research Site
  - Ulm, Germany, 89077
    - Not yet recruiting
    - Research Site
  - Weyhe, Germany, 28844
    - Not yet recruiting
    - Research Site
Greece
- - Athens, Greece, 11521
    - Not yet recruiting
    - Research Site
  - Athens, Greece, 11527
    - Not yet recruiting
    - Research Site
  - Athens, Greece, 11526
    - Not yet recruiting
    - Research Site
  - Athens, Greece, 11528
    - Not yet recruiting
    - Research Site
  - Athens, Greece, 15123
    - Not yet recruiting
    - Research Site
  - Dragana, Greece, 68100
    - Not yet recruiting
    - Research Site
  - Heraklio, Greece, 71110
    - Not yet recruiting
    - Research Site
  - Heraklion, Greece, 71409
    - Not yet recruiting
    - Research Site
  - Thessaloniki, Greece, 54636
    - Not yet recruiting
    - Research Site
  - Voula, Greece, 16673
    - Not yet recruiting
    - Research Site
Hungary
- - Balatonfüred, Hungary, 8230
    - Not yet recruiting
    - Research Site
  - Budapest, Hungary, 1122
    - Not yet recruiting
    - Research Site
  - Budapest, Hungary, 1134
    - Not yet recruiting
    - Research Site
  - Budapest, Hungary, 1132
    - Not yet recruiting
    - Research Site
  - Dunaújváros, Hungary, 2400
    - Not yet recruiting
    - Research Site
  - Kaposvár, Hungary, 7400
    - Not yet recruiting
    - Research Site
  - Miskolc, Hungary, 3530
    - Not yet recruiting
    - Research Site
  - Nyíregyháza, Hungary, 4400
    - Not yet recruiting
    - Research Site
  - Orosháza, Hungary, 5900
    - Not yet recruiting
    - Research Site
  - Szeged, Hungary, 6725
    - Not yet recruiting
    - Research Site
  - Szombathely, Hungary, 9700
    - Not yet recruiting
    - Research Site
  - Zalaegerszeg, Hungary, 8900
    - Not yet recruiting
    - Research Site
India
- - Belagavi, India, 590010
    - Not yet recruiting
    - Research Site
  - Calicut, India, 673008
    - Not yet recruiting
    - Research Site
  - Coimbatore, India, 641018
    - Not yet recruiting
    - Research Site
  - Dehradun, India, 248001
    - Not yet recruiting
    - Research Site
  - Delhi, India, 110029
    - Not yet recruiting
    - Research Site
  - Delhi, India, 110062
    - Not yet recruiting
    - Research Site
  - Hyderabad, India, 500035
    - Not yet recruiting
    - Research Site
  - Jaipur, India, 302017
    - Not yet recruiting
    - Research Site
  - Kanpur, India, 208001
    - Not yet recruiting
    - Research Site
  - Kochi, India, 682018
    - Not yet recruiting
    - Research Site
  - Kochi, India, 682040
    - Not yet recruiting
    - Research Site
  - Kolkata, India, 700020
    - Not yet recruiting
    - Research Site
  - Kolkata, India, 700014
    - Not yet recruiting
    - Research Site
  - Ludhiana, India, 141001
    - Not yet recruiting
    - Research Site
  - Meerut, India, 250005
    - Not yet recruiting
    - Research Site
  - Mumbai, India, 400012
    - Not yet recruiting
    - Research Site
  - Nagpur, India, 441108
    - Not yet recruiting
    - Research Site
  - New Delhi, India, 110017
    - Not yet recruiting
    - Research Site
  - Rudrapur, India, 263153
    - Not yet recruiting
    - Research Site
  - Vadodara, India, 390002
    - Not yet recruiting
    - Research Site
Italy
- - Ancona, Italy, 60100
    - Not yet recruiting
    - Research Site
  - Bergamo, Italy, 24127
    - Not yet recruiting
    - Research Site
  - Brescia, Italy, 25123
    - Not yet recruiting
    - Research Site
  - Milan, Italy, 20132
    - Not yet recruiting
    - Research Site
  - Pavia, Italy, 27100
    - Not yet recruiting
    - Research Site
  - Perugia, Italy, 06132
    - Not yet recruiting
    - Research Site
  - Riccione, Italy, 47838
    - Not yet recruiting
    - Research Site
  - Salerno, Italy, 84131
    - Not yet recruiting
    - Research Site
  - Sesto San Giovanni, Italy, 20099
    - Not yet recruiting
    - Research Site
  - Vizzolo Predabissi, Italy, 20070
    - Not yet recruiting
    - Research Site
Japan
- - Aomori, Japan, 030-8553
    - Not yet recruiting
    - Research Site
  - Chikushino-shi, Japan, 818-8516
    - Not yet recruiting
    - Research Site
  - Chūōku, Japan, 103-0027
    - Not yet recruiting
    - Research Site
  - Fukui-shi, Japan, 910-8526
    - Not yet recruiting
    - Research Site
  - Fukushima, Japan, 960-1295
    - Not yet recruiting
    - Research Site
  - Higashiibaraki-gun, Japan, 311-3193
    - Not yet recruiting
    - Research Site
  - Higashiohmi-shi, Japan, 527-8505
    - Not yet recruiting
    - Research Site
  - Iwakuni-shi, Japan, 740-8510
    - Not yet recruiting
    - Research Site
  - Kagoshima, Japan, 890-8760
    - Not yet recruiting
    - Research Site
  - Kamakura-shi, Japan, 247-8533
    - Not yet recruiting
    - Research Site
  - Kanazawa, Japan, 920-8650
    - Not yet recruiting
    - Research Site
  - Kashihara-shi, Japan, 634-8522
    - Not yet recruiting
    - Research Site
  - Kasugai-shi, Japan, 486-8510
    - Not yet recruiting
    - Research Site
  - Kawagoe-shi, Japan, 350-8550
    - Not yet recruiting
    - Research Site
  - Kishiwada-shi, Japan, 596-0042
    - Not yet recruiting
    - Research Site
  - Kitakyusyu-shi, Japan, 806-8501
    - Not yet recruiting
    - Research Site
  - Kobe, Japan, 654-0155
    - Not yet recruiting
    - Research Site
  - Kobe, Japan, 650-0017
    - Not yet recruiting
    - Research Site
  - Kobe, Japan, 650-0047
    - Not yet recruiting
    - Research Site
  - Kobe, Japan, 654-0081
    - Not yet recruiting
    - Research Site
  - Kure-shi, Japan, 737-0193
    - Not yet recruiting
    - Research Site
  - Kyoto, Japan, 604-8845
    - Not yet recruiting
    - Research Site
  - Kyoto, Japan, 605-0981
    - Not yet recruiting
    - Research Site
  - Maebashi, Japan, 371-8511
    - Not yet recruiting
    - Research Site
  - Matsusaka-shi, Japan, 515-8557
    - Not yet recruiting
    - Research Site
  - Minatoku, Japan, 108-0073
    - Not yet recruiting
    - Research Site
  - Mito, Japan, 311-4198
    - Recruiting
    - Research Site
  - Morioka, Japan, 020-0066
    - Not yet recruiting
    - Research Site
  - Nagasaki, Japan, 851-0301
    - Not yet recruiting
    - Research Site
  - Nagoya, Japan, 454-8502
    - Not yet recruiting
    - Research Site
  - Nagoya, Japan, 466-8560
    - Not yet recruiting
    - Research Site
  - Nagoya, Japan, 467-8602
    - Not yet recruiting
    - Research Site
  - Osaka, Japan, 558-8558
    - Withdrawn
    - Research Site
  - Sagamihara-shi, Japan, 252-0315
    - Not yet recruiting
    - Research Site
  - Sapporo, Japan, 003-0026
    - Recruiting
    - Research Site
  - Sayama-shi,, Japan, 350-1305
    - Not yet recruiting
    - Research Site
  - Sendai, Japan, 981-3133
    - Not yet recruiting
    - Research Site
  - Shibuya-ku, Japan, 150-0013
    - Not yet recruiting
    - Research Site
  - Shizuoka, Japan, 420-8630
    - Not yet recruiting
    - Research Site
  - Shizuoka, Japan, 420-8527
    - Withdrawn
    - Research Site
  - Suginami City, Japan, 168-0065
    - Not yet recruiting
    - Research Site
  - Suita, Japan, 565-0862
    - Not yet recruiting
    - Research Site
  - Suzuka-shi, Japan, 513-8630
    - Not yet recruiting
    - Research Site
  - Tachikawa-shi, Japan, 190-8531
    - Not yet recruiting
    - Research Site
  - Takaoka-shi, Japan, 933-8555
    - Not yet recruiting
    - Research Site
  - Takatsuki-shi, Japan, 569-8686
    - Not yet recruiting
    - Research Site
  - Tokushima, Japan, 770-8503
    - Not yet recruiting
    - Research Site
  - Toshima-ku, Japan, 171-0014
    - Not yet recruiting
    - Research Site
  - Toyama, Japan, 930-8550
    - Not yet recruiting
    - Research Site
  - Ueda-shi, Japan, 386-8610
    - Not yet recruiting
    - Research Site
  - Urasoe-Shi, Japan, 901-2102
    - Not yet recruiting
    - Research Site
  - Urayasu-shi, Japan, 279-0021
    - Not yet recruiting
    - Research Site
  - Uruma, Japan, 904-2293
    - Not yet recruiting
    - Research Site
  - Utsunomiya, Japan, 320-8580
    - Not yet recruiting
    - Research Site
  - Wakayama, Japan, 640-8158
    - Not yet recruiting
    - Research Site
  - Yakushi, Japan, 581-0011
    - Not yet recruiting
    - Research Site
  - Yokohama, Japan, 236-0004
    - Not yet recruiting
    - Research Site
  - Yokohama, Japan, 236-0037
    - Not yet recruiting
    - Research Site
  - Yokohama, Japan, 224-8503
    - Not yet recruiting
    - Research Site
  - Yokohama, Japan, 231-8682
    - Not yet recruiting
    - Research Site
  - Ōmihachiman, Japan, 523-0082
    - Not yet recruiting
    - Research Site
Malaysia
- - Alor Star, Malaysia, 05460
    - Not yet recruiting
    - Research Site
  - Cheras, Malaysia, 56000
    - Not yet recruiting
    - Research Site
  - Kajang, Malaysia, 43000
    - Not yet recruiting
    - Research Site
  - Kuala Lumpur, Malaysia, 50586
    - Not yet recruiting
    - Research Site
  - Kuala Lumpur, Malaysia, 59100
    - Not yet recruiting
    - Research Site
  - Kuala Lumpur, Malaysia, 50400
    - Not yet recruiting
    - Research Site
  - Kuala Terengganu, Malaysia, 20400
    - Not yet recruiting
    - Research Site
  - Kuantan, Malaysia, 25100
    - Not yet recruiting
    - Research Site
  - Kuching, Malaysia, 93586
    - Not yet recruiting
    - Research Site
  - Miri, Malaysia, 98000
    - Not yet recruiting
    - Research Site
  - Sungai Buloh, Malaysia, 47000
    - Not yet recruiting
    - Research Site
Mexico
- - Guadalajara, Mexico, 44676
    - Not yet recruiting
    - Research Site
  - Monterrey, Mexico, 64460
    - Not yet recruiting
    - Research Site
  - Monterrey, Mexico, 64060
    - Not yet recruiting
    - Research Site
  - Monterrey, Mexico, 64030
    - Not yet recruiting
    - Research Site
  - México, Mexico, 14080
    - Not yet recruiting
    - Research Site
  - México, Mexico, 06090
    - Not yet recruiting
    - Research Site
  - Querétaro, Mexico, 76000
    - Not yet recruiting
    - Research Site
  - San Luis Potosí City, Mexico, 78200
    - Not yet recruiting
    - Research Site
  - Tijuana, Mexico, 22150
    - Withdrawn
    - Research Site
  - Xalapa, Mexico, 91193
    - Not yet recruiting
    - Research Site
  - Zapopan, Mexico, 45070
    - Not yet recruiting
    - Research Site
Netherlands
- - Alkmaar, Netherlands, 1815 JD
    - Not yet recruiting
    - Research Site
  - Almere Stad, Netherlands, 1315 RA
    - Not yet recruiting
    - Research Site
  - Amstelveen, Netherlands, 1186 AM
    - Not yet recruiting
    - Research Site
  - Doetinchem, Netherlands, 7009 BL
    - Not yet recruiting
    - Research Site
  - Leeuwarden, Netherlands, 8934 AD
    - Not yet recruiting
    - Research Site
  - Rotterdam, Netherlands, 3015
    - Not yet recruiting
    - Research Site
  - Sneek, Netherlands, 8601 ZR
    - Not yet recruiting
    - Research Site
  - The Hague, Netherlands, 2545 AA
    - Not yet recruiting
    - Research Site
  - Tilburg, Netherlands, 5042 AD
    - Not yet recruiting
    - Research Site
  - Zutphens, Netherlands, 7207 AE
    - Not yet recruiting
    - Research Site
  - Zwolle, Netherlands, 8025 AB
    - Not yet recruiting
    - Research Site
Poland
- - Bialystok, Poland, 15-375
    - Not yet recruiting
    - Research Site
  - Bialystok, Poland, 15-481
    - Not yet recruiting
    - Research Site
  - Częstochowa, Poland, 42-217
    - Not yet recruiting
    - Research Site
  - Gdynia, Poland, 81-338
    - Not yet recruiting
    - Research Site
  - Gdynia, Poland, 81-157
    - Not yet recruiting
    - Research Site
  - Katowice, Poland, 40-635
    - Not yet recruiting
    - Research Site
  - Katowice, Poland, 40-600
    - Not yet recruiting
    - Research Site
  - Krakow, Poland, 31-271
    - Not yet recruiting
    - Research Site
  - Krakow, Poland, 30-082
    - Suspended
    - Research Site
  - Krakow, Poland, 30-901
    - Not yet recruiting
    - Research Site
  - Poznan, Poland, 61-848
    - Not yet recruiting
    - Research Site
  - Przemyśl, Poland, 37-700
    - Not yet recruiting
    - Research Site
  - Radzionków, Poland, 41-922
    - Not yet recruiting
    - Research Site
  - Skórzewo, Poland, 60-185
    - Not yet recruiting
    - Research Site
  - Szczecin, Poland, 71-526
    - Not yet recruiting
    - Research Site
  - Torun, Poland, 87-100
    - Not yet recruiting
    - Research Site
  - Warsaw, Poland, 02-758
    - Not yet recruiting
    - Research Site
  - Warsaw, Poland, 04-628
    - Not yet recruiting
    - Research Site
  - Wroclaw, Poland, 50-981
    - Not yet recruiting
    - Research Site
  - Włocławek, Poland, 87-800
    - Not yet recruiting
    - Research Site
Romania
- - Baia Mare, Romania, 430124
    - Not yet recruiting
    - Research Site
  - Brasov, Romania, 500102
    - Not yet recruiting
    - Research Site
  - Bucharest, Romania, 050098
    - Not yet recruiting
    - Research Site
  - Bucharest, Romania, 031441
    - Not yet recruiting
    - Research Site
  - Bucharest, Romania, 050659
    - Not yet recruiting
    - Research Site
  - Craiova, Romania, 200505
    - Not yet recruiting
    - Research Site
  - Satu Mare, Romania, 440055
    - Not yet recruiting
    - Research Site
  - Timișoara, Romania, 300002
    - Not yet recruiting
    - Research Site
  - Timișoara, Romania, 300024
    - Not yet recruiting
    - Research Site
  - Timișoara, Romania, 300362
    - Not yet recruiting
    - Research Site
Slovakia
- - Bratislava, Slovakia, 83101
    - Not yet recruiting
    - Research Site
  - Bratislava, Slovakia, 82107
    - Not yet recruiting
    - Research Site
  - Bratislava, Slovakia, 83101
    - Withdrawn
    - Research Site
  - Brezno, Slovakia, 977 01
    - Not yet recruiting
    - Research Site
  - Košice, Slovakia, 04001
    - Not yet recruiting
    - Research Site
  - Košice, Slovakia, 04022
    - Not yet recruiting
    - Research Site
  - Lučenec, Slovakia, 984 01
    - Not yet recruiting
    - Research Site
  - Lučenec, Slovakia, 98401
    - Not yet recruiting
    - Research Site
  - Nitra, Slovakia, 949 11
    - Not yet recruiting
    - Research Site
  - Prešov, Slovakia, 08001
    - Not yet recruiting
    - Research Site
  - Svidník, Slovakia, 08901
    - Not yet recruiting
    - Research Site
  - Šahy, Slovakia, 93601
    - Not yet recruiting
    - Research Site
South Korea
- - Busan, South Korea, 49201
    - Not yet recruiting
    - Research Site
  - Busan, South Korea, 49267
    - Not yet recruiting
    - Research Site
  - Daegu, South Korea, 42601
    - Not yet recruiting
    - Research Site
  - Daejeon, South Korea, 35015
    - Not yet recruiting
    - Research Site
  - Gwangju, South Korea, 61469
    - Not yet recruiting
    - Research Site
  - Gyeonggi-do, South Korea, 13620
    - Not yet recruiting
    - Research Site
  - Incheon, South Korea, 22332
    - Not yet recruiting
    - Research Site
  - Incheon, South Korea, 21431
    - Not yet recruiting
    - Research Site
  - Seongbuk-Gu, South Korea, 02841
    - Not yet recruiting
    - Research Site
  - Seoul, South Korea, 3722
    - Not yet recruiting
    - Research Site
  - Seoul, South Korea, 06591
    - Not yet recruiting
    - Research Site
  - Seoul, South Korea, 5505
    - Not yet recruiting
    - Research Site
  - Seoul, South Korea, 04763
    - Not yet recruiting
    - Research Site
  - Seoul, South Korea, 05278
    - Not yet recruiting
    - Research Site
  - Suwon, South Korea, 16499
    - Not yet recruiting
    - Research Site
  - Uijeongbu-si, South Korea, 11765
    - Not yet recruiting
    - Research Site
  - Yangsan, South Korea, 50612
    - Not yet recruiting
    - Research Site
Spain
- - Barcelona, Spain, 08035
    - Not yet recruiting
    - Research Site
  - Barcelona, Spain, 08036
    - Not yet recruiting
    - Research Site
  - Barcelona, Spain, 08003
    - Not yet recruiting
    - Research Site
  - Jaén, Spain, 23007
    - Not yet recruiting
    - Research Site
  - Madrid, Spain, 28034
    - Not yet recruiting
    - Research Site
  - Madrid, Spain, 28041
    - Not yet recruiting
    - Research Site
  - Murcia, Spain, 30120
    - Not yet recruiting
    - Research Site
  - Salamanca, Spain, 37007
    - Not yet recruiting
    - Research Site
  - Sanlúcar de Barrameda (Cádiz), Spain, 11540
    - Not yet recruiting
    - Research Site
  - Seville, Spain, 41013
    - Not yet recruiting
    - Research Site
  - Valencia, Spain, 46014
    - Not yet recruiting
    - Research Site
  - Valencia, Spain, 46010
    - Not yet recruiting
    - Research Site
  - Valencia, Spain, 46026
    - Not yet recruiting
    - Research Site
  - Villamartín, Spain, 11650
    - Not yet recruiting
    - Research Site
Sweden
- - Gothenburg, Sweden, 416 85
    - Not yet recruiting
    - Research Site
  - Jönköping, Sweden, 553 05
    - Not yet recruiting
    - Research Site
  - Karlstad, Sweden, 651 85
    - Not yet recruiting
    - Research Site
  - Lund, Sweden, 222 21
    - Not yet recruiting
    - Research Site
  - Mölndal, Sweden, SE431 80
    - Not yet recruiting
    - Research Site
  - Stockholm, Sweden, 113 61
    - Not yet recruiting
    - Research Site
  - Stockholm, Sweden, 171 64
    - Not yet recruiting
    - Research Site
  - Stockholm, Sweden, 118 83
    - Withdrawn
    - Research Site
  - Stockholm, Sweden, 112 19
    - Not yet recruiting
    - Research Site
  - Uppsala, Sweden, 751 85
    - Not yet recruiting
    - Research Site
  - Örebro, Sweden, 701 85
    - Not yet recruiting
    - Research Site
Taiwan
- - Kaohsiung City, Taiwan, 80756
    - Not yet recruiting
    - Research Site
  - New Taipei City, Taiwan, 220
    - Not yet recruiting
    - Research Site
  - New Taipei City, Taiwan, 231
    - Not yet recruiting
    - Research Site
  - Taichung, Taiwan, 40201
    - Not yet recruiting
    - Research Site
  - Taichung, Taiwan, 40705
    - Not yet recruiting
    - Research Site
  - Taichung, Taiwan, 433004
    - Not yet recruiting
    - Research Site
  - Taipei, Taiwan, 11101
    - Not yet recruiting
    - Research Site
  - Taipei, Taiwan, 10002
    - Not yet recruiting
    - Research Site
  - Taipei, Taiwan, 11217
    - Not yet recruiting
    - Research Site
  - Taipei, Taiwan, 10449
    - Not yet recruiting
    - Research Site
  - Taipei, Taiwan, 11490
    - Not yet recruiting
    - Research Site
  - Taipei, Taiwan, 110
    - Withdrawn
    - Research Site
  - Taoyuan, Taiwan, 333
    - Not yet recruiting
    - Research Site
  - Yilan, Taiwan, 260
    - Not yet recruiting
    - Research Site
Thailand
- - Bangkok, Thailand, 10700
    - Not yet recruiting
    - Research Site
  - Bangkok, Thailand, 10330
    - Not yet recruiting
    - Research Site
  - Bangkok, Thailand, 10300
    - Not yet recruiting
    - Research Site
  - Changwat Sara Buri, Thailand, 18000
    - Not yet recruiting
    - Research Site
  - Chiang Mai, Thailand, 50200
    - Not yet recruiting
    - Research Site
  - Hat Yai, Thailand, 90110
    - Not yet recruiting
    - Research Site
  - Khlong Luang, Thailand, 12120
    - Not yet recruiting
    - Research Site
  - Khon Kaen, Thailand, 40002
    - Not yet recruiting
    - Research Site
  - Phitsanulok, Thailand, 65000
    - Not yet recruiting
    - Research Site
  - Ratchaburi, Thailand, 70000
    - Not yet recruiting
    - Research Site
Turkey (Türkiye)
- - Adana, Turkey (Türkiye), 01330
    - Not yet recruiting
    - Research Site
  - Ankara, Turkey (Türkiye), 06530
    - Not yet recruiting
    - Research Site
  - Antalya, Turkey (Türkiye), 07100
    - Not yet recruiting
    - Research Site
  - Center, Turkey (Türkiye), 23200
    - Not yet recruiting
    - Research Site
  - Center, Turkey (Türkiye), 78200
    - Not yet recruiting
    - Research Site
  - Istanbul, Turkey (Türkiye), 34300
    - Not yet recruiting
    - Research Site
  - Izmir, Turkey (Türkiye), 35330
    - Not yet recruiting
    - Research Site
  - Kahramanmaraş, Turkey (Türkiye), 46100
    - Withdrawn
    - Research Site
  - Kütahya, Turkey (Türkiye), 43100
    - Not yet recruiting
    - Research Site
  - Odunpazari, Turkey (Türkiye), 26080
    - Not yet recruiting
    - Research Site
  - Odunpazari, Turkey (Türkiye), 26040
    - Not yet recruiting
    - Research Site
  - Yenimahalle, Turkey (Türkiye), 06170
    - Not yet recruiting
    - Research Site
Ukraine
- - Kyiv, Ukraine, 02002
    - Not yet recruiting
    - Research Site
  - Kyiv, Ukraine, 03037
    - Not yet recruiting
    - Research Site
  - Kyiv, Ukraine, 04210
    - Not yet recruiting
    - Research Site
  - Kyiv, Ukraine, 03057
    - Not yet recruiting
    - Research Site
  - Kyiv, Ukraine, 04050
    - Not yet recruiting
    - Research Site
  - Kyiv, Ukraine, 03049
    - Not yet recruiting
    - Research Site
  - Kyiv, Ukraine, 01601
    - Not yet recruiting
    - Research Site
  - Kyiv, Ukraine, 03151
    - Not yet recruiting
    - Research Site
  - Kyiv, Ukraine, 04114
    - Not yet recruiting
    - Research Site
  - Lviv, Ukraine, 79016
    - Not yet recruiting
    - Research Site
  - Uzhhorod, Ukraine, 88014
    - Not yet recruiting
    - Research Site
  - Uzhhorod, Ukraine, 88002
    - Not yet recruiting
    - Research Site
United Arab Emirates
- - Abo Dhabi, United Arab Emirates, 20011
    - Not yet recruiting
    - Research Site
  - Abu Dhabi, United Arab Emirates, 11001
    - Not yet recruiting
    - Research Site
  - Abu Dhabi, United Arab Emirates, 48481
    - Not yet recruiting
    - Research Site
United Kingdom
- - Ashton-under-Lyne, United Kingdom, OL6 6EW
    - Not yet recruiting
    - Research Site
  - Basildon, United Kingdom, SS16 5NL
    - Not yet recruiting
    - Research Site
  - Belfast, United Kingdom, BT16 1RH
    - Not yet recruiting
    - Research Site
  - Birmingham, United Kingdom, B75 7RR
    - Not yet recruiting
    - Research Site
  - Brighton, United Kingdom, BN2 5BE
    - Not yet recruiting
    - Research Site
  - Bristol, United Kingdom, BS34 5TF
    - Not yet recruiting
    - Research Site
  - Cardiff, United Kingdom, CF14 4XW
    - Not yet recruiting
    - Research Site
  - Clydebank, United Kingdom, G81 4DY
    - Not yet recruiting
    - Research Site
  - Dundee, United Kingdom, DD1 9SY
    - Not yet recruiting
    - Research Site
  - Glasgow, United Kingdom, G51 4TF
    - Not yet recruiting
    - Research Site
  - Kings Lynn, United Kingdom, PE30 4ET
    - Not yet recruiting
    - Research Site
  - Leeds, United Kingdom, LS1 3EX
    - Not yet recruiting
    - Research Site
  - London, United Kingdom, EC1M 6BQ
    - Not yet recruiting
    - Research Site
  - Sandbach, United Kingdom, CW11 1EQ
    - Not yet recruiting
    - Research Site
  - Southampton, United Kingdom, SO303JB
    - Not yet recruiting
    - Research Site
  - Woodbridge, United Kingdom, IP136TH
    - Not yet recruiting
    - Research Site
United States
- Alabama
  - Fairhope, Alabama, United States, 36532
    - Recruiting
    - Research Site
- Alaska
  - Anchorage, Alaska, United States, 99508
    - Not yet recruiting
    - Research Site
- Arizona
  - Gilbert, Arizona, United States, 85295
    - Not yet recruiting
    - Research Site
  - Surprise, Arizona, United States, 85374
    - Not yet recruiting
    - Research Site
- California
  - Beverly Hills, California, United States, 90211
    - Not yet recruiting
    - Research Site
  - Huntington Beach, California, United States, 92647
    - Not yet recruiting
    - Research Site
  - Huntington Park, California, United States, 90255
    - Not yet recruiting
    - Research Site
  - Loma Linda, California, United States, 92354
    - Not yet recruiting
    - Research Site
  - Lomita, California, United States, 90717
    - Not yet recruiting
    - Research Site
  - Mather, California, United States, 95655
    - Not yet recruiting
    - Research Site
  - Northridge, California, United States, 91324
    - Not yet recruiting
    - Research Site
  - Palo Alto, California, United States, 94304
    - Not yet recruiting
    - Research Site
  - Redding, California, United States, 96001
    - Not yet recruiting
    - Research Site
  - San Diego, California, United States, 92117
    - Not yet recruiting
    - Research Site
  - Tarzana, California, United States, 91356
    - Withdrawn
    - Research Site
- Colorado
  - Colorado Springs, Colorado, United States, 80909
    - Not yet recruiting
    - Research Site
- Connecticut
  - New Haven, Connecticut, United States, 06519
    - Not yet recruiting
    - Research Site
- Florida
  - Bradenton, Florida, United States, 34209
    - Withdrawn
    - Research Site
  - Hallandale, Florida, United States, 33009
    - Not yet recruiting
    - Research Site
  - Jacksonville, Florida, United States, 32209
    - Not yet recruiting
    - Research Site
  - Lakeland, Florida, United States, 33813
    - Not yet recruiting
    - Research Site
  - Miami, Florida, United States, 33125
    - Not yet recruiting
    - Research Site
  - Miami, Florida, United States, 33144
    - Not yet recruiting
    - Research Site
  - Miami, Florida, United States, 33176
    - Not yet recruiting
    - Research Site
  - Miami Lakes, Florida, United States, 33016
    - Recruiting
    - Research Site
  - Miami Lakes, Florida, United States, 33014
    - Withdrawn
    - Research Site
  - Ocoee, Florida, United States, 34761
    - Withdrawn
    - Research Site
  - Palmetto Bay, Florida, United States, 33157
    - Not yet recruiting
    - Research Site
  - Riverview, Florida, United States, 33578
    - Not yet recruiting
    - Research Site
- Georgia
  - Atlanta, Georgia, United States, 30303
    - Not yet recruiting
    - Research Site
  - Columbus, Georgia, United States, 31904
    - Not yet recruiting
    - Research Site
  - Tucker, Georgia, United States, 30084
    - Not yet recruiting
    - Research Site
- Illinois
  - Champaign, Illinois, United States, 61822
    - Withdrawn
    - Research Site
  - Chicago, Illinois, United States, 60640
    - Not yet recruiting
    - Research Site
  - Gurnee, Illinois, United States, 60031
    - Not yet recruiting
    - Research Site
  - Melrose Park, Illinois, United States, 60160
    - Not yet recruiting
    - Research Site
  - Moline, Illinois, United States, 61265
    - Not yet recruiting
    - Research Site
  - Niles, Illinois, United States, 60714
    - Not yet recruiting
    - Research Site
  - Rockford, Illinois, United States, 61107
    - Not yet recruiting
    - Research Site
  - Schaumburg, Illinois, United States, 60173
    - Not yet recruiting
    - Research Site
  - Winfield, Illinois, United States, 60190
    - Not yet recruiting
    - Research Site
- Indiana
  - Indianapolis, Indiana, United States, 46254
    - Not yet recruiting
    - Research Site
- Iowa
  - Waterloo, Iowa, United States, 50701
    - Not yet recruiting
    - Research Site
- Kansas
  - Leavenworth, Kansas, United States, 66048
    - Not yet recruiting
    - Research Site
  - Wichita, Kansas, United States, 67214
    - Not yet recruiting
    - Research Site
- Kentucky
  - Owensboro, Kentucky, United States, 42301
    - Not yet recruiting
    - Research Site
- Louisiana
  - Bossier City, Louisiana, United States, 71111
    - Not yet recruiting
    - Research Site
  - Covington, Louisiana, United States, 70433
    - Not yet recruiting
    - Research Site
  - Lafayette, Louisiana, United States, 70503
    - Not yet recruiting
    - Research Site
  - New Orleans, Louisiana, United States, 70121
    - Not yet recruiting
    - Research Site
  - Shreveport, Louisiana, United States, 71105
    - Not yet recruiting
    - Research Site
  - Zachary, Louisiana, United States, 70791
    - Not yet recruiting
    - Research Site
- Maryland
  - Annapolis, Maryland, United States, 21401
    - Not yet recruiting
    - Research Site
  - Baltimore, Maryland, United States, 21229
    - Not yet recruiting
    - Research Site
  - Lanham, Maryland, United States, 20706
    - Not yet recruiting
    - Research Site
  - Oxon Hill, Maryland, United States, 20745
    - Not yet recruiting
    - Research Site
- Massachusetts
  - Boston, Massachusetts, United States, 02114
    - Not yet recruiting
    - Research Site
  - Boston, Massachusetts, United States, 02118
    - Not yet recruiting
    - Research Site
  - New Bedford, Massachusetts, United States, 02740
    - Not yet recruiting
    - Research Site
  - Worcester, Massachusetts, United States, 01655
    - Withdrawn
    - Research Site
- Michigan
  - Flint, Michigan, United States, 48503
    - Not yet recruiting
    - Research Site
  - Southfield, Michigan, United States, 48075
    - Not yet recruiting
    - Research Site
  - Southfield, Michigan, United States, 48076
    - Not yet recruiting
    - Research Site
  - Troy, Michigan, United States, 48098
    - Not yet recruiting
    - Research Site
- Missouri
  - Bridgeton, Missouri, United States, 63044
    - Not yet recruiting
    - Research Site
  - Kansas City, Missouri, United States, 64111
    - Not yet recruiting
    - Research Site
  - Kansas City, Missouri, United States, 64111
    - Withdrawn
    - Research Site
- Nebraska
  - Lincoln, Nebraska, United States, 68510
    - Not yet recruiting
    - Research Site
- New Jersey
  - Bridgewater, New Jersey, United States, 08807
    - Not yet recruiting
    - Research Site
  - Millville, New Jersey, United States, 08332
    - Not yet recruiting
    - Research Site
  - Sewell, New Jersey, United States, 08080
    - Not yet recruiting
    - Research Site
  - Trenton, New Jersey, United States, 08690
    - Not yet recruiting
    - Research Site
  - Vineland, New Jersey, United States, 08360
    - Not yet recruiting
    - Research Site
- New York
  - Brooklyn, New York, United States, 11220
    - Recruiting
    - Research Site
  - Buffalo, New York, United States, 14215
    - Not yet recruiting
    - Research Site
  - New York, New York, United States, 10019
    - Not yet recruiting
    - Research Site
  - New York, New York, United States, 10001
    - Not yet recruiting
    - Research Site
  - Rosedale, New York, United States, 11422
    - Not yet recruiting
    - Research Site
  - The Bronx, New York, United States, 10451
    - Not yet recruiting
    - Research Site
  - The Bronx, New York, United States, 10455
    - Not yet recruiting
    - Research Site
- North Carolina
  - Chapel Hill, North Carolina, United States, 27514
    - Not yet recruiting
    - Research Site
  - Durham, North Carolina, United States, 27710
    - Not yet recruiting
    - Research Site
  - Greensboro, North Carolina, United States, 27401
    - Not yet recruiting
    - Research Site
  - Statesville, North Carolina, United States, 28677
    - Not yet recruiting
    - Research Site
  - Wilmington, North Carolina, United States, 28401
    - Not yet recruiting
    - Research Site
- North Dakota
  - Fargo, North Dakota, United States, 58104
    - Not yet recruiting
    - Research Site
  - Grand Forks, North Dakota, United States, 58201
    - Not yet recruiting
    - Research Site
- Ohio
  - Columbus, Ohio, United States, 43215
    - Not yet recruiting
    - Research Site
  - Columbus, Ohio, United States, 43228
    - Withdrawn
    - Research Site
  - Dayton, Ohio, United States, 45435
    - Not yet recruiting
    - Research Site
  - Maumee, Ohio, United States, 43537
    - Not yet recruiting
    - Research Site
- Oklahoma
  - Oklahoma City, Oklahoma, United States, 73134
    - Not yet recruiting
    - Research Site
- Pennsylvania
  - Bethlehem, Pennsylvania, United States, 18015
    - Withdrawn
    - Research Site
  - Media, Pennsylvania, United States, 19063
    - Not yet recruiting
    - Research Site
  - Philadelphia, Pennsylvania, United States, 19104
    - Not yet recruiting
    - Research Site
  - Philadelphia, Pennsylvania, United States, 19107
    - Not yet recruiting
    - Research Site
  - Smithfield, Pennsylvania, United States, 15478
    - Not yet recruiting
    - Research Site
  - Yardley, Pennsylvania, United States, 19067
    - Not yet recruiting
    - Research Site
- Rhode Island
  - East Providence, Rhode Island, United States, 02914
    - Not yet recruiting
    - Research Site
- South Carolina
  - Spartanburg, South Carolina, United States, 29303
    - Not yet recruiting
    - Research Site
- South Dakota
  - Rapid City, South Dakota, United States, 57701
    - Not yet recruiting
    - Research Site
- Texas
  - Dallas, Texas, United States, 75216
    - Not yet recruiting
    - Research Site
  - DeSoto, Texas, United States, 75115
    - Not yet recruiting
    - Research Site
  - El Paso, Texas, United States, 79905
    - Not yet recruiting
    - Research Site
  - Houston, Texas, United States, 77025
    - Not yet recruiting
    - Research Site
  - Houston, Texas, United States, 77082
    - Not yet recruiting
    - Research Site
  - Humble, Texas, United States, 77338
    - Not yet recruiting
    - Research Site
  - Plano, Texas, United States, 75093
    - Withdrawn
    - Research Site
  - San Antonio, Texas, United States, 78231
    - Not yet recruiting
    - Research Site
  - San Antonio, Texas, United States, 78257
    - Not yet recruiting
    - Research Site
  - Tomball, Texas, United States, 77375
    - Recruiting
    - Research Site
  - Tyler, Texas, United States, 75701
    - Not yet recruiting
    - Research Site
  - Victoria, Texas, United States, 77901
    - Not yet recruiting
    - Research Site
- Vermont
  - Burlington, Vermont, United States, 05401
    - Withdrawn
    - Research Site
- Virginia
  - Arlington, Virginia, United States, 22205
    - Not yet recruiting
    - Research Site
- Washington
  - Redmond, Washington, United States, 98052
    - Recruiting
    - Research Site
- West Virginia
  - Kingwood, West Virginia, United States, 26537
    - Not yet recruiting
    - Research Site
  - Morgantown, West Virginia, United States, 26505
    - Not yet recruiting
    - Research Site
Vietnam
- - Can Tho, Vietnam, 900000
    - Not yet recruiting
    - Research Site
  - Hanoi, Vietnam, 100000
    - Not yet recruiting
    - Research Site
  - Ho Chi Minh City, Vietnam, 70000
    - Not yet recruiting
    - Research Site
  - Ho Chi Minh City, Vietnam, 700000
    - Not yet recruiting
    - Research Site
  - Ho Chi Minh City, Vietnam, 700000
    - Withdrawn
    - Research Site
  - Hochiminh, Vietnam, 700000
    - Not yet recruiting
    - Research Site
  - Hochiminh City, Vietnam, 700000
    - Not yet recruiting
    - Research Site
  - Hà Nội, Vietnam, 100000
    - Not yet recruiting
    - Research Site

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

Adult
Older Adult

Accepts Healthy Volunteers

Description

Inclusion Criteria:

Left ventricular ejection fraction (LVEF) of > 40% within 12 months prior to screening.
Structural heart disease evidence.
HF diagnosed with New York Heart Association (NYHA) Class II-IV at the time of screening.

Exclusion Criteria:

BMI <25 kg/m² at screening.
Diabetes exclusions:
History of type 1 diabetes.
HbA1c ≥10% at screening.
Currently receiving or anticipated to receive therapeutic intervention for diabetic retinopathy and/or macular edema.
more than 1 episode of severe hypoglycemic event within 180 days prior to screening, or hypoglycemia unawareness/poor recognition.
Renal exclusions:
On a prespecified renal replacement therapy, or eGFR below a prespecified threshold at screening
Cardiovascular exclusions:
Major cardiac surgery, coronary revascularization, valvular repair/replacement, AF/AFL ablation, CRT implantation, or ICD without CRT within 90 days prior to screening, or planned after randomization.
Heart failure due to infiltrative cardiomyopathy, active myocarditis, constrictive pericarditis, cardiac tamponade, genetic hypertrophic cardiomyopathy (including obstructive), or arrhythmogenic right ventricular cardiomyopathy/dysplasia.
GI exclusions:
Clinically significant upper GI condition affecting gastric emptying, drug absorption, or safety/tolerability interpretation; chronic use of drugs directly affecting GI motility; severe disease or prior surgery.
History of acute or chronic pancreatitis.
Endocrine exclusions:
History/ family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2, or basal calcitonin ≥35 ng/L at screening.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Quadruple

Number of Arms

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Elecoglipron Elecoglipron tablet once daily	Drug: Elecoglipron Elecoglipron tablet
Active Comparator: Placebo Placebo matching Elecoglipron tablet once daily	Drug: Placebo Placebo tablet

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of CV death or HHF/urgent HF visit Time Frame: Up to 42 months	Time to first event of the composite of: CV death HHF Urgent HF visit	Up to 42 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
To evaluate the effect of elecoglipron compared with placebo in reducing the rate of HF events (HHF or urgent HF visit) Time Frame: Up to 42 months	Total occurrences (first and recurrent) of: HF events HHF Urgent HF visit	Up to 42 months
To evaluate the effect of elecoglipron compared to placebo on improving patient-reported outcomes using a questionnaire. Time Frame: Baseline and 52 weeks	Change from baseline to Week 52	Baseline and 52 weeks
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of the 4-point composite of all-cause death, HHF, MI, or stroke Time Frame: Up to 42 months	Time to first event of the composite of: All-cause death HHF MI Stroke	Up to 42 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

AstraZeneca

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 24, 2026

Primary Completion (Estimated)

September 3, 2029

Study Completion (Estimated)

September 3, 2029

Study Registration Dates

First Submitted

August 3, 2026

First Submitted That Met QC Criteria

August 7, 2026

First Posted (Actual)

August 12, 2026

Study Record Updates

Last Update Posted (Actual)

September 9, 2026

Last Update Submitted That Met QC Criteria

September 4, 2026

Last Verified

September 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

D7266C00001
2026-526304-79-00 (Ctis)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

Qualified researchers can request access to anonymized individual patient-level data from AstraZeneca group of companies sponsored clinical trials via the request portal Vivli.org. All requests will be evaluated as per the AZ disclosure commitment: https://astrazenecagrouptrials.pharmacm.com/ST/Submission/Disclosure.

Yes, indicates that AZ are accepting requests for IPD, but this does not mean all requests will be shared.

IPD Sharing Time Frame

AstraZeneca will meet or exceed data availability as per the commitments made to the EFPIA PhRMA Data Sharing Principles. For details of our timelines, please rerefer to our disclosure commitment at https://astrazenecagrouptrials.pharmacm.com/ST/Submission/Disclosure.

IPD Sharing Access Criteria

When a request has been approved AstraZeneca will provide access to the anonymized individual patient-level data via secure research environment Vivli.org. Signed Data Usage Agreement (non-negotiable contract for data accessors) must be in place before accessing requested information.

IPD Sharing Supporting Information Type

STUDY_PROTOCOL
SAP

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF (Elevate-HF)

A Phase III, Randomized, Double-blind, Parallel-group, Placebo-controlled, Multicenter Study to Evaluate the Effect of Elecoglipron in Reducing Cardiovascular Outcomes in Participants With HFpEF and HFmrEF (Elevate-HF)

Study Overview

Status

Conditions

Intervention / Treatment

Study Type

Enrollment (Estimated)

Phase

Contacts and Locations

Study Contact

Study Locations

Participation Criteria

Eligibility Criteria

Ages Eligible for Study

Accepts Healthy Volunteers

Description

Study Plan

How is the study designed?

Design Details

Number of Arms

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Secondary Outcome Measures

Outcome Measure

Measure Description

Time Frame

Collaborators and Investigators

Sponsor

Study record dates

Study Major Dates

Study Start (Actual)

Primary Completion (Estimated)

Study Completion (Estimated)

Study Registration Dates

First Submitted

First Submitted That Met QC Criteria

First Posted (Actual)

Study Record Updates

Last Update Posted (Actual)

Last Update Submitted That Met QC Criteria

Last Verified

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

IPD Plan Description

IPD Sharing Time Frame

IPD Sharing Access Criteria

IPD Sharing Supporting Information Type

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Studies a U.S. FDA-regulated device product