Predictors of Mesh Infection After Open Incisional Hernioplasty

To determine the frequency of mesh infection in patient with open Incisional hernioplasty and to compare factors contributing with and without mesh infection

Study Overview

• Status: Completed
• Conditions: Predictor of Mesh Condition

Detailed Description

This prospective observational study will evaluate predictors of mesh infection following open incisional hernioplasty. Eligible patients with incisional hernia undergoing open mesh repair will be consecutively enrolled at the Department of Surgery, Dr. Faisal Masood Teaching Hospital, Sargodha. Demographic, clinical, anthropometric, and relevant perioperative factors will be recorded using a structured data collection form.

Patients will be followed postoperatively at 1 month, 3 months, and 1 year to assess the development of mesh infection and other related outcomes. Patients who develop mesh infection will be compared with those who remain infection-free to identify significant predictors. Data will be analyzed using SPSS version 26, with appropriate statistical tests and logistic regression to determine independent predictors of mesh infection.

• Study Type: Observational
• Enrollment (Actual): 62

Contacts and Locations

Study Locations

• Pakistan
  • Punjab Province
    • Sargodha, Punjab Province, Pakistan, 40100
      • Dr Faisal Masood teaching Hospital Sargodha

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Patient of all age group and both genders with Incisional hernia undergoing open mesh hernioplasty will be consecutively enrolled and followed postoperative to access the development of mesh infection and associated predictors

Description

Inclusion Criteria:

1. All age group patient will be included
2. Both genders will be involved in this study
3. Incisional hernia as per operational definition

Exclusion Criteria:

1. Co- Morbid condition including hypertension, Tuberculosis and Autoimmune disease
2. Parents refusing for consent
3. Immunocompromised patient

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Mesh infection; Participants undergoing open Incisional hernioplasty who develop mesh related infection during the postoperative followup period

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number and percentage of participants with Mesh related infection following open Incisional hernioplasty	Development of mesh related infection following open Incisional hernioplasty assessed during postoperative followup will be accessed by clinical examination of the surgical site. The outcome will be measured as the number of participants who developed mesh related infection and percentage of mesh related infection.	1 month, 3 months and 1 year after surgery

Collaborators and Investigators

• Sponsor: Sargodha Medical College

Study record dates

Study Major Dates

• Study Start (Actual): September 22, 2025
• Primary Completion (Actual): July 25, 2026
• Study Completion (Actual): July 29, 2026

Study Registration Dates

• First Submitted: August 22, 2026
• First Submitted That Met QC Criteria: August 25, 2026
• First Posted (Actual): August 27, 2026

Study Record Updates

• Last Update Posted (Actual): August 27, 2026
• Last Update Submitted That Met QC Criteria: August 25, 2026
• Last Verified: August 1, 2026

More Information

Terms related to this study

• Other Study ID Numbers: SMC-GS-2026-012

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No