Short-Axis Versus Long-Axis Ultrasound-Guided Radial Artery Cannulation

August 31, 2026 updated by: Fikret Salık, Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Comparison of Short-Axis and Long-Axis Approaches for Ultrasound-Guided Radial Artery Cannulation: The Effect of Radial Artery Depth on Technique Selection-A Randomized Controlled Trial

This randomized controlled study aims to compare short-axis/out-of-plane and long-axis/in-plane ultrasound-guided techniques for radial artery cannulation in adult patients undergoing elective surgery. The study will also investigate whether the depth of the radial artery from the skin is associated with cannulation success and may help guide the selection of the ultrasound-guided cannulation technique.

Participants will be randomly assigned to either the short-axis/out-of-plane group or the long-axis/in-plane group. Radial artery depth will be measured using ultrasound before cannulation. The two techniques will be compared in terms of cannulation success, including first-attempt success, number of punctures and needle redirections, time to successful cannulation, failed cannulation, and procedure-related complications.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

144

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Turkey (Türkiye)
      • Diyarbakır, Turkey (Türkiye)
        • Recruiting
        • Gazi Yasargil Training and Research Hospital
        • Contact:
    • Diyarbakır
      • Diyarbakır, Diyarbakır, Turkey (Türkiye)
        • Recruiting
        • Dicle University Faculty of Medicine
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

nclusion Criteria:

Age 18 years or older Patients with an indication for radial artery cannulation for invasive arterial monitoring Undergoing a surgical or interventional procedure Radial artery suitable for visualization by ultrasound Provision of written informed consent

Exclusion Criteria:

Age younger than 18 years Infection, burn, scar, or skin lesion at the planned cannulation site Previous vascular surgery involving the study extremity Advanced peripheral arterial disease or radial artery occlusion Inadequate collateral circulation as assessed by the Allen test or ultrasound Severe coagulopathy Presence of an arteriovenous fistula in the study extremity Severe hemodynamic instability Multiple previous failed radial artery cannulation attempts in the same extremity Pregnancy Allergy to ultrasound gel Refusal to participate in the study

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Short-Axis/Out-of-Plane Approach
Participants assigned to this group will undergo ultrasound-guided radial artery cannulation using the short-axis/out-of-plane approach.
Procedure: Short-Axis/Out-of-Plane Radial Artery Cannulation
Ultrasound-guided radial artery cannulation will be performed using the short-axis/out-of-plane approach. The radial artery will be visualized in the short-axis view, and the needle will be advanced using an out-of-plane technique until successful arterial cannulation.
Active Comparator: Long-Axis/In-Plane Approach
Participants assigned to this group will undergo ultrasound-guided radial artery cannulation using the long-axis/in-plane approach.
Procedure: Long-Axis/In-Plane Radial Artery Cannulation
Ultrasound-guided radial artery cannulation will be performed using the long-axis/in-plane approach. The radial artery will be visualized in the long-axis view, and the needle will be advanced using an in-plane technique until successful arterial cannulation.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Success Rate of Short-Axis/Out-of-Plane Versus Long-Axis/In-Plane Radial Artery Cannulation
Time Frame: During the radial artery cannulation procedure
The success rates of ultrasound-guided radial artery cannulation using the short-axis/out-of-plane and long-axis/in-plane approaches will be compared. Successful cannulation is defined according to the study protocol as successful radial artery catheter placement within the predefined procedural criteria.
During the radial artery cannulation procedure

Secondary Outcome Measures

Outcome Measure
Time Frame
First-Attempt Cannulation Success
Time Frame: During the radial artery cannulation procedure
During the radial artery cannulation procedure

Other Outcome Measures

Outcome Measure
Time Frame
Number of Puncture Attempts
Time Frame: Time to Successful Radial Artery Cannulation
Time to Successful Radial Artery Cannulation
Procedure-Related Complications
Time Frame: During the radial artery cannulation procedure
During the radial artery cannulation procedure
Number of Needle Redirections
Time Frame: During the radial artery cannulation procedure
During the radial artery cannulation procedure

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Investigators

  • Principal Investigator: Fikret Salik, MD, Dicle University Faculty of Medicine

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

August 25, 2026

Primary Completion (Estimated)

December 15, 2026

Study Completion (Estimated)

December 30, 2026

Study Registration Dates

First Submitted

August 31, 2026

First Submitted That Met QC Criteria

August 31, 2026

First Posted (Actual)

September 3, 2026

Study Record Updates

Last Update Posted (Actual)

September 3, 2026

Last Update Submitted That Met QC Criteria

August 31, 2026

Last Verified

August 1, 2026

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 399

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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