The DREAM-VR Study: Does a Virtual Reality Tool Help Dental Students Master Acute Medical Emergencies Better? (DREAM-VR)

September 3, 2026 updated by: Denise van Diermen

The DREAM-VR Study: Dental Students' Readiness for Emergency Assessment and Management Through Virtual Reality

The goal of this prospective educational cross-over study is to compare the competency and self-reported confidence in managing acute medical emergencies in fourth year dental students at the Academic Centre for Dentistry (ACTA) after training with a Virtual Reality (VR) training tool. The main questions it aims to answer are:

  • Do students who were trained with the VR tool perform better or equally good as students who were trained with a traditional training, in managing acute medical emergencies?
  • Do students who were trained with the VR tool score higher in self-reported confidence scores? Researchers will compare the group who trained with the VR tool with a group who received a traditional training with a mannikin to see if students from one of these methods performs better at a clinical exam in managing an acute emergency that is played by a trained actor. They will also be compared with themselves, since after 4 weeks the groups will be crossed-over and will receive the other training with different clinical scenarios.

Half of the participants will

  • In week 1-4:
  • Play a VR scenario and watch peer students play other VR scenario's
  • Fill out a written peer-feedback form and discuss this with peers
  • Fill out 3 short online questionnairs, before the training, just before the formative clinical exam and just after the formative clinical exam
  • Participate in a formative clinical exam with a trained actor
  • In week 5-8:
  • Play a scenario with a mannikin and watch peer students play other scenario's*
  • Fill out a written peer-feedback form and discuss this with peers
  • Fill out 2 short online questionnairs, just before the summative clinical exam and just after the summative clinical exam
  • Participate in a summative clinical exam with a trained actor* The other half of the participants will participate in the same protocol, but in the reverse order. They start with the traditional training with a mannikin in week 1-4 and cross-over to VR in week 5-8.

    • The training program with a mannikin and the summative clinical exam is part of the regular curriculum.

Study Overview

Study Type

Interventional

Enrollment (Estimated)

140

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

    • North Holland
      • Amsterdam, North Holland, Netherlands, 1081 LA
        • Academic Center for Dentistry Amsterdam

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • 4th year dental students at ACTA who participate in the course Medical Dental Interaction in september-october 2026

Exclusion Criteria:

  • students who experience severe side-effects of the VR tool, such as severe dizziness, nausea or headche
  • students who do not provide informed consent

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Non-Randomized
  • Interventional Model: Crossover Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: VR group
Dental students that practice with a VR tool for managing acute medical emergencies
Students are immersed in a virtual dental clinic. They see a virtual patient in the dental chair (avatar). The avatar can be controlled by the teacher to show signs of acute medical emergencies. The student can talk to the avatar, the avatar can talk back. The student can use virtual tools, such as blood pressure device, oximeter, etc. to diagnose the emergency and can apply virtual medication such as epinephrine injection, oxigen, etc. They can play 7 different scenario's: fainting, asthma attack, anaphylaxis, stroke, heart attack, epilepsy, hypoglycemia. They can call 911/112 to ask for an ambulance and can do a medical handover to the ambulance personell.
Active Comparator: Mannikin group
Dental students that practice with a resuscitation mannikin for managing acute medical emergencies.
Students are told by the teacher that the mannikin is a dental patient that experiences an acute medical emergency, and what the patients' complaints are. The students can use diagnostic devices, such as blood pressure tool and oximeter, to practice. The teacher tells what the outcome of measurement is and the student proposes a diagnosis and treatment plan. They can give the mannikin test medication such as epinehrin or oxigen.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Competence in diagnosing and treating acute medical emergencies in the dental practice
Time Frame: From enrollment assessment takes place in Week 4 and week 8

In week 4 the students will do a formative clinical test with a trained actor, who plays an acute medical emergency scenario. The topic of the scenario will be randomly assigned by drawing a lot. The students will be scored using a validated scoring table, that measures all the necessary steps in the DRS ABCDE protocol. They can obtain a maximum score of 80 when they do all the necessary steps to manage the acute emergency.

Again in week 8 the students will do a summative clinical test with a trained actor. The topic of the scenario be randomly assigned. The students will be scored using the same validated scoring table. They will pass the test if they used the adequate diagnostic tools, made the correct diagnosis and communicated effectively with the ambulance personnel. The point score on the scoring table will only be used for research purposes.

From enrollment assessment takes place in Week 4 and week 8
Self-reported competence in managing acute medical emergencies
Time Frame: From enrollment until week 4 and 8

Students will be asked to fill out 5 online surveys to report on their experienced sense of competence. The questions will be on a 5 point likert scale.

T=0: before enrolling in the training T=1: just before the formative clinical test in week 4 T=2: just after the formative clinical test in week 4 T=3: just before the summative clinical test in week 8 T=4: just after the summative clinical test in week 8

From enrollment until week 4 and 8
Self-reported confidence in managing acute medical emergencies
Time Frame: From enrollment in week 4 and 8

Students will be asked to fill out 5 online surveys to report on their experienced sense of confidence. The questions will be on a 5 point likert scale.

T=0: before enrolling in the training T=1: just before the formative clinical test in week 4 T=2: just after the formative clinical test in week 4 T=3: just before the summative clinical test in week 8 T=4: just after the summative clinical test in week 8

From enrollment in week 4 and 8

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Effects of order and carry-over effects in the cross-over design
Time Frame: From enrollment until week 8
To assess whether the order in which participants receive the virtual reality training and the comparator training affects outcome scores, and whether exposure to the first intervention has a residual effect on outcomes measured after the second intervention. Intervention sequence (VR-first versus comparator-first), study period, and prior intervention exposure will be evaluated in a mixed-effects model, accounting for repeated measurements within participants.
From enrollment until week 8

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Students' subjective experiences with the use of the VR tool
Time Frame: From enrollment until week 8
A short online questionnaire with closed questions with a 5 point Liket scale and open questions will evaluate the subjective experiences and feedback of the students who participated in the study
From enrollment until week 8

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Investigators

  • Principal Investigator: Denise E van Diermen, MD, PhD, Academic Centrer for Dentistry Amsterdam

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

August 31, 2026

Primary Completion (Estimated)

October 31, 2026

Study Completion (Estimated)

October 31, 2026

Study Registration Dates

First Submitted

August 30, 2026

First Submitted That Met QC Criteria

September 3, 2026

First Posted (Actual)

September 10, 2026

Study Record Updates

Last Update Posted (Actual)

September 10, 2026

Last Update Submitted That Met QC Criteria

September 3, 2026

Last Verified

September 1, 2026

More Information

Terms related to this study

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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